' Average' genotype' frequencies' in' the' model' with ...

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The! frequencies! are! color;coded! according! to! the! legend! on! the! right.! Stars! indicate! an! excess! of! homozygotes.! ! ch value. Genotype at. B4galnt2 ch=0.
ch value

Genotype at B4galnt2

ch=0

ch=ci/2

ch=ci

1

1 0.9

CC individuals

1 0

0.7 0.6 0.5 0.4

1 0

Heterozygotes

Cost of bleeding (cb)

0.8

0.3 0.2

RR individuals 0.1

0

0

0

10

10

Cost of infection (ci)

1

! Figure' S4:' Average' genotype' frequencies' in' the' model' with' a' frequencyBdependent' environment.' The! frequencies! are! displayed!according! to! the! value! of! ch,! the! cost! of! bleeding! (y! axis)! and! of! infection! (x! axis).! The! average! genotype! frequencies! across! 100! simulations! using! the! HWE;process,! each! with! 10000! generations,! are! displayed.! The! frequencies! are! color;coded! according! to! the! legend! on! the! right.! Stars! indicate! an! excess! of! homozygotes.! !

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