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IL10+IL4 synergy. + IL4 inhibition. No inhibition. 0. 200. 400. 600. 800. 0. 100. 200. 300. 400. 500. 600. 700. 800. 900. Time in Days. Bacteria. IL10+IL4 synergy.
800

900 IL10+IL4 synergy + IL4 inhibition No inhibition

600

800 700

300

400 300 200

100

100 0

200

400 600 Time in Days

0

800

5000

400 200

0

200

400 600 Time in Days

0

800

CFU

IL−10

300

200

400 600 Time in Days

800

0

800

40 30 20

100

0

400 600 Time in Days

IL10+IL4 synergy + IL4 inhibition No inhibition

50

200

1000

200

60

400

2000

0

70 +IL4 inhibition No inhibition IL10+IL4 synergy

500

3000

0

600

600 IL10+IL4 synergy + IL4 inhibition No inhibition

4000

Th2 cells

500

200

0

800 Th1 cells

400

No inhibiton +Th1 IL4 inhibition IL10+IL4 synergy

1000

600

500

Bacteria

Infected macrophages

700

1200 IL10+IL4 synergy + IL4 inhibition No inhibition

10 0

200

400 600 Time in Days

800

0

0

200

400 600 Time in Days

800