Figure S4. (A). (B). 0. 250. 500. 0. 4. 8 x 10. −3. T (min). Density. 0. 50. 100. 150. 0. 0.5. 1 t (min). Scaled concentration. MAPKKK*. MAPKK−PP. MAPK−PP.
Figure S4 (A)
(B) −3
x 10
Scaled concentration
Density
8
4
0 0
250 T (min)
500
MAPKKK* MAPKK−PP MAPK−PP
1
0.5
0 0
50
100
150
t (min)
(A) Distribution of the periods of oscillatory solutions for the MAPK cascade. For each “Oscillatory” bifurcation diagram, a single oscillatory solution is evaluated at the point xm as defined in Figure S3C and the corresponding period is computed. The peak of the distribution is around 30 minutes. (B) One typical oscillatory solution for the MAPK cascade. The vertical axis corresponds to the concentrations of MAPKKK*, MAPKK-PP and MAPK-PP, scaled by the corresponding total concentrations of MAPKKK, MAPKKK and MAPK respectively.
