PQF LRWF E EWAEE F CR I KK I KLGKVKEACR - - DDSKKL - YCSHNGYDCTKT I RNKD I LSDNPKCTGCSVKCKVYE LWLRNQRNE F EKQKKKY PQF LRWF T EWAEE F CR I RK I KLGKVKNECR - - GE TSGKRYCSGDGYDCTKTD I SRN I F YMDLDCPRCE EECRKYDEW I ENKENELDKQKNKY PQF LRWF E EWAEE F CR I KK I KL ENVKNACR - - DEKKRK - YCSLNGFDCTQT I WKKKVFGRGNDCTNCSF KCF PYE I WLGNQREAFRKQKEKY PQF LRWFDEWAEE F CRRNK I K I DKTKE ECR - - GGNNGK - NCSREGYDCKRTDLGNN I I FMDL ECPNCADACKMYNRW I ENKKSE FNKQKQKY PQF LRWFNEWAEDF CR I KN I K I EHVTKTCT - - GESNNK - HCSREGYDCKRTDLKKNE I FMDLECPRCE E ECTSYNEWLKKKEGE FNKQKKKY PQF LRWFNEWAEE F CRVREHKLKK I KEACR - - GGNNKK - ECSKEGYDCKKTN I KRNE I F VDLDCPRCE EECTSYNEWLKKKEGE FNKQNNKY PQF LRWFDEWADDF CR I RNHKLQKVKEACR - - DERRGK - YCSLNGFDCTQT I WKKGVLHWSNECTDCSVKCNLYE I WLGNQREAFRKQKEKY PQYLRWFQEWAEDF CR I KK I KL E LAKKACR - - DESSKL - YCSHNGYDCTKR I EKGKSCSRDSKCTECSTKC I PYEYWLEKQQNE FNMQKDKY PQF LRWF E EWAEE F CRKKK I KLGNVKKACR - - DESSKL - YCSHNGYDCTQT I RNKD I C I RESKCTDCSTKCKLYE LWL EKQENE F KKQTKKY PQF LRWFNEWAEE F CR I RK I K I DKTKEEC I - - GENNGK - NCSREGYDCNKTNLKLNE I F VDLDCPRCEKACTSYNEW I ENKKKE F KKQKRKY PQYLRWF E EWAEDF CRKRN I KLKSAKNACR - - NESKQL - YCSHNGYDCTKR I EKGKSCSRDSKCT ECSTKC I PYEYWL EKQQNE FNMQKDKY PQF LRWFDEWSEDF CR I KK I KLGRVKKACR - - DESSKL - YCSHNGYDCTKT I RNKD I C I RESKCTGCLVKCNPYE I WLENQRKE FDKQKEKY PQF LRWYDEWAE E F CR I RK I K I EN I KKVCR - - DESNE I - YCSGDGHDCTQTNLSHNQ I F VDLDCPRCQDQC I KYNEW I VKKLE E F SKQKKKY PQYLRWFDEWGEE F CRKRN I KLKKVKDSCC - - NDKERL - YCCHDGYDCT TT I WKKGSLHLDNKCTDCL TKCKVF EVWLGNQQEAF KKQKEKY PQYLRWFDEWGEE F CRKRN I KLKKVKDSCR - - NYKERL - YCSHNGYDCTT T I WRKG I LHLDNKCTDCSTKCKVF EVWLGNQQEAF KKQKEKY PQF LRWFDEWSEE F CRKRN I TLKSAKEECQ - - NDSKKL - YCSLNGYNCTRL I PNKNYCSRDP I CTPCSNKC I PYDLWLRNRRDE FNMQKGKY PQF LRWYDEWADDF CR I RNHKLQKVKDTCQGYNNSGYR I YCSGDGEDCTN I LKQNFN I VSDF F CPSCKT ECTNYKKW I NKKQGE FNKQKKKY PQF LRWFDEWAEE F CR I RK I KL ENVKKECR - - DEPNNK - YCSGDGHDCKRTYLKDNT I F I DLNCPRCENACSNYTKW I E I QRKQFDKQKRKY PQF LRWF E EWSEE F CR I KK I K I DKVKKECR - - DEQNKK - YCSGDGHDCTQTNLSHNQ I F VDLDCPRCQDQC I KYNEW I VKKLE E F YKQNLKY PQF LRWF E EWAEE F CR I KK I KL ENVKKACR - - DESSKL - YCSHNGYDCTQT I RNKD I C I RESKCTDCSTKCKLYELWLEKQENE F KKQKQKY PQF LRWYDEWAEDF CR I RYHKLKR I KDACR - - NEKNGK - YCSHNGYDCRQMSWKKN I ESREHYCTGCF SACS I YNMWVDKQKKE F EKQKEKY PQYLRWFDEWAEDF CR I RKDKLKK I KNACR - - NYANNL - YCSFNGYDCTK I I WKEHNF SNDSKCTKCHNECLRYENW I KDQKLKF EKQRDKY PQF LRWFNEWAEE F CR I RK I KLGRVKKACR - - DESSKL - YCSHNGYDCTKT I RNKD I C I RESKCTDCSTKCKLYE I WLGNQRKE F EKQTKKY PQF LRWF E EWAEE F CR I RYHKLKR I KDACR - - NDSKKL - YCSHNGYDCTKTSWKKGVLHWSNECTDCSVKCKLYE I WLGNQREAFRKQKEKY PQYLRWFDEWSEE F CR I KN I K I GKVKNACR - - GEKHEK - DCSREGYDCKRTDLKKNE I FMDLECPNCADACKMYNRW I ENKKSE FNKQKQKY PQF LRWFNEWAEE F CR I RK I KL ENVKKACR - - DDSKKL - YCSHNGYDC I E T I RNED I LSDNPKCTGCSVKCKVYELWLRNQRNE F EKQKKKY PQF LRWFDEWADDF CR I KK I KL ENVKNACR - - DEKKRK - YCSLNGFDCTQT I WKKGVLHRSNECTGCLVKCNPYE I WLGNQREAFRKQKEKY PQF VRWF E EWADDF CR I RKHKLKN I KDVCR - - NESKPL - YCSLNGYDCTKTSWKNDF ESREHYCTPCF SACSLYK I WVANQKKE F EKQKKKY PQF LRWFDEWAEE F CR I KN I K I GN I KKSCT - - GESNNK - HCSREGYDCNKTNLRLNE I FMDL ECPRCADDCKSYE TWVENKKKE FNKQKEKY PQF LRWLNEWSE E F CR I KN I K I GN I KKSCT - - GESNNK - HCSREGYDCNKTNLRLNE I FMDL ECPRCADDCKSYE TWVEKKKKE FNKQKKKY PQF LRWFDEWAEE F CR I RNHKLRK I KDACR - - NDKERL - YCSQNGYDCTKR I EKGSSCSRENKCTGCSNKCVDYDFWL EKQQNE F K I QKDKY PQYLRWFDEWGEE F CRKRK I KL ENVEKACR - - KDSEKL - YCRHNGYDCTKT I KNEN I L FDDPKCTDCL I KCSLYE I WLDNQQKE F EKQKEKY -
PQYLRWF E EWAEDF CRKKKKYVD I VKTNCR - - NY - - SRNLYCSGNGLDCQE T I RV I GHHV I GSECSKCSVWCRRYKKW I DNQKEE F LKQKKKC PQYLRWF E EWAEDF CRKRKKK I ENA I KNCRGE - K - GNER - YCDLNGYNCEE TARGAE I F VKGDDCHKCSVACDRF VKW I DNQRKE FDKQKKKY PQF LRWF E EWAEDF CRLRKHKLKDA I QKCREKHK - GAKKLYCDLNRYDCEQTASGKHDF F EEDDCKGCQYSCARF VNW I DNQKKE F LKQKKKY PQYLRWF E EWAEDF CRKKKKKL ENL EKQCRGKD - KSDEYRYCSRNGYDCEQT I SRKGKVRMGKGCTDCF F ACHSYENW I DNQRKQFDKQKKYT PQYLRWF E EWAEDF CR I KQLKLQNVKNSCRG - EDD - - - NKYCSRNGYDCEQT I NK I GHRRFGNGC I KCL F ECNPYVKW I GNKEKDF EKQKKKC PQYLRWF E EWAEDF CRLRKHKL ENAKNKCRKPN - - - GVEKYCDLNRYDCEKTASGKHDF F EDDVCKDCQYSCAP F VDW I DNQKLE F LKQRNKY PQYLRWF E EWAEDF CTKRKHKLQNA I K I CRGDS - - - GNDRYCDLNGYDCTKTARGKNKRF SNDECYKCSLPCDHF VPW I DNQQKE F EKQKKKY PQYLRWF E EWAEDF CRKKKHKLKDA I DKCRGQYQ - D - ADRYCDLNGYDCEKTKRG I NMYRWDHKCTGCF LSCSHFRTW I DNQKEQFHKQKK I Y PQYLRWF E EWAE E F CR I KE LKL ENVKTRCRG - EKDG - - EKYCSRNGYDCTGT I I KRN I FRPDPECTNCL F ECNHYQDW I DNKKKE F EKQKKKC PQYLRWF E EWAEDF CRKKNKKLKDVKTNCRGDSG - - - TDRYCSGNGYDCTQT I RA I GKLV I GEHCTNCSVWCRLYEKW I DNQKLE F LKQRNKY PQYLRWF E EWAEDF CRKKKKKLPNVKTNCR - GEN - - NK - KYCSGDGFDCTKT I RAKY I YA I GDECTKCSFWCGF YKKWLENQKQE F LKQKKKY PQYLRWF E EWAEDF CRKKNKKLNDVKKQCR - GDN - - GTDRYCSGNGYDCTKT I RA I GKYA I GDECTKCSFWCRMYETW I DNQKKE F LKQKRKY PQYLRWF E EWAEDF CRKKK I YVG I VKKYCL - - - DE T E - EKYCSLNGCDCTQTVRAKGKLRYGNRCTDCL F ACHRYEKW I DNQRKQF LKQRNKY PQYLRWF E EWAEDF CRLRKHKLKDA I DKCRGGS - - - SNDKYCSGNGFDCVE TVRGDEHF VEK - DCHDCSYSCSP F VKW I DNQKLE LDKQKKKY PQYLRWFDEWT EDF CRKRKSQL ENA I QNCRGKDE - YGE EKYCSPNGHDCKT T I RAKD I YS I SKECAKCF F SCHRYVKW I DNQKLE F EKQKENY PQYLRWF E EWAEDF CRKKKKF LD I VKTNCR - GEN - - GSERYCSFNGYDCEKT I NK I DHLVMGNNCTKCSVACRLYQKW I ENQKQE F I KQKKKY PQYLRWLQEWAEDF CTKRKHKLKDA I QKCRGQYQ - - GKERYCDLNGYDCKGTARGKNKYKYEHDC I ECSF SC I P F TNW I DNQKLE F LKQKEKY PQYLRWF E EWAEDF CRKREYKL ENAKNKCRGNYE - NGEPKYCSRNGYDCKKTVRGKN I LVSDT ECTKCSVVCTP F VKW I DNQKEE F LKQKEKY PQYLRWF E EWAEDF CRKRKHKL ENA I QKCRYN - E - NGE EKYCSRNGYDCTRT I RGKNKL F SDT ECTNCSVVCTP F VDW I DNKKKE F EKQKGKY PQYLRWF E EWAEDF CRKKKKKL ENLDTQCRGTDA - SKEPRYCSLNGCDCTKTVRARGKLRYGNRCTDCL F ACNPYVHW I DKKKEE FNKQVKKY PQYLRWFDEWSEDF CRKKKKKL ENVQKQCRGKYGDDDT ERYCSRNGYDCEQTVNARGKLRYGKQC I SCLYACNPYVEW I DKQRKQFDKQKNRY PQF LRWF E EWSEDF CRKKNKK I KDVKRNCRGER - - - DGEKYCSRNGYDCEKTKRA I GKYHMGNQCTKCL F ACNPYVEW I DNQRKQFDKQVKKY PQYLRWF E EWAE E F CTKRKHKLQNA I TNCR - DY - - - AQNLYCSGNGYNCKE T I RAENKLVEGDDCHKCSVSCKP F VKW I DNQKLE F EKQKKKY PQYLRWF E EWAEDF CRKRKHKL ENA I KNCRGE - - - KGNERYCSRNGYDC I NTVR I QGKLVKGSECDDCYSSCTP F VKW I DDKKQE F LKQKKKY PQYLRWF E EWAEDF CGKKKKF LD I VKTNCR - GKN - - GTDRYCSFNGYDCEKT I NK I DHLVMGNNCTKCSVACRLYQKW I ENQKQE F I KQKKKY PQF LRWF E EWAEDF CRKKKKKL ENL EQQCRGEG - - - GKERYCSGNGYDCEKT I YKKGKLV I SSECTKCSVWCRMYETW I DNQKKE F I KQKRKY PQYLRWF E EWAEDF CRKRKRKL EDA I QKCRKPK - - - GQPKYCDLNRHDCVE T I RGNHVF F EEDDCKDCQYSCSHF VNW I DNQKLE F LKQKEKY PQYLRWF E EWAEDF CRKRKKKL ENA I KNCRY - DE - SGEPKYCDLNGYNCEE TARGRNKF APDSNCNKCSVACKP F VEWLDNQQKE F EKQKKKY PQYLRWF E EWAEDF CRKKKKYVN I VKK FCRE - - GENGE EKYCSRNGYDCTKTKPA I GKYRMGNQCTKCL F ACNPYVEW I EKQKEQFDKQKEKY PQYLRWF E EWAEDF CRKKKKKVENLQKQCRGQY - Q - GEKRYCSRNGCDCTKTVRAKGKLRYGKQC I SCLYACNPYVEW I DNQKEQFDKQKQRY PQF LRWF E EWAEDF CRLRKRKLKDA I QKCRGKDK - DGKKLYCDLNRYDCEKTASGKHDF F EEDDCKDCHF SCARF VKW I DNQKLE F LKQKQKY PQYLRWF E EWAEDF CRKKNKKVENVKKQCRKKDN - SSDDRYCSRNGYDCEKTKRA I GKLRYGKGCTECF F ACNPYVEW I EKQKEQFDKQKKKY PQYLRWF E EWAEDF CRKRKKQL ENAKKYCRGEDG - SGKELYCDLNRYDCKKT I SAEQKLVKGDDCNKCSVVC I P FGPW I DNQKLE F LKQKNKY PQYLRWF E EWAEDF CRLRKHKLQNAKNKCREKHK - DGKKLYCDLNGFDCTQTARGKNKYKYEHDC I ECYSSCDHF VHW I DNQKKE F EKQKNKY PQHLRWFDEWSEE F CRKRKDQLK I SL EKCRGKNK - D - - - KYCSLNGCNCKTTVRGKKKFDYQQECNDCLVACDP F VHW I DNEKLE F LKQKKKY PQYLRWF E EWAEDF CRKKK I KVENVKKSCRGEDK - ESKDRYCSRNGYDCEKTKRA I GKLRYGKQC I SCLYGCNPYVDW I EKQKEQFDKQKK I Y PQYLRWF E EWAEDF CRKKKKYVD I VKTNCR - GES - - GKDKYCSGDGFDCTKTVRAKG I YA I GDDCHKCSFWCGF YKKWLANQKQE F LKQKKKC PQF LRWF E EWAEDF CRKRKHKL ENA I DKCRGKN - 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B 1 10 20 30 40 50 60 70 80 90 . . . . | . . . . | . . . . | . . . . | . . . . | . . . . | . . . . | . . . . | . . . . | . . . . | . . . . | . . . . | . . . . | . . . . | . . . . | . . . .| . . . . | . . . . | . . . SD3 Group A P Q F L R W F x E W x E x F C R x x x x K L x x x K x x C x - - x x x x x x - - Y C S x x G Y D C x x x x x x x x x x x x x x x C x x C x x x C x x Y x x W xx x x x x x F x K Q K x K Y SD3 Group B P Q Y L R W F E E W A E D F C R K x K x K x x x x x x x C R x x x x x x x x x x Y C x x N G x D C x x T x x x x x x x x x x x x C x x C x x x C x x x x x W I D N Q K x x F x K Q K x KY
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SD3 Group B 1 10 20 30 40 50 60 70 80 90 . . . . | . . . . | . . . . | . . . . | . . . . | . . . . | . . . . | . . . . | . . . . | . . . . | . . . . | . . . . | . . . . | . . . . | . . . . | . . . . |. . . . | . . . . | . .. P Q Y L R W F E E W A E D F C R K x K x K x x x x x x x C R x x x x x x x x x x Y C x x N G x D C x x T x x x x x x x x x x x x C x x C x x x C x x x x x W I D N Q K x x F x K Q K x KY