42 Vitamin D Deficiency in Patients with Systemic Lupus Erythematosus

1 downloads 0 Views 901KB Size Report
Sep 30, 2012 - deficiency in Saudi married couples. Eur J Clin Nutr 2012 Jun;66(6):742-745. 28. Walport MJ. Complement and systemic lupus erythematosus.
Oman Medical Journal (2013) Vol. 28, No. 1:42-47 DOI 10. 5001/omj.2013.10


Vitamin D Deficiency in Patients with Systemic Lupus Erythematosus Suzan M. Attar and Aisha M. Siddiqui Received: 30 Sep 2012 / Accepted: 16 Nov 2012 © OMSB, 2013



Objectives: Hypovitaminosis D is common in the general population. Many studies that have been conducted to show the association between vitamin D deficiency and systemic lupus erythematosus (SLE) reveal that deficiencies in vitamin D are common in this group of patients. Our aim was to study the relationship between 25(OH)D and disease activity in patients with SLE. Methods: Retrospective cohort study of patients with SLE who were followed up at King Abdulaziz University Hospital, Jeddah, from January 2007 to November 2010. Demographic and clinical data were recorded and the 25(OH)D levels of the patients were measured. Chi square tests, Student’s t-test, ANOVA and Pearson tests were used for data analysis. ANOVA test was followed by Bonferroni correction. A p-value 120 mmol/L or estimated glomerular filtration rate 801 IU/mL. Complement components 3 and 4 (C3 and C4) were measured by nephelometry, and hypocomplementemia was defined as a level below the lower normal value (C3