International Journal of Pharmacy and Pharmaceutical Sciences ISSN- 0975-1491
Vol 9, Issue 2, 2017
Original Article
A COMPARATIVE STUDY OF EFFICACY AND SAFETY OF LORNOXICAM AND DICLOFENAC AS POSTOPERATIVE ANALGESICS AFTER MASTOIDECTOMY SURGERY R. NALINI1, J. EZHILRAMYA2 1,2Government
Tirunelveli Medical College, Department of Pharmacology, Tirunelveli Email:
[email protected]
Received: 07 Sep 2016 Revised and Accepted: 07 Dec 2016 ABSTRACT Objective: The objective of the research was to evaluate the efficacy and safety of lornoxicam compared to diclofenac in the management of postoperative pain following mastoidectomy surgery. Methods: The present study was a prospective, single-blinded, randomised study. 80 mastoidectomy patients were randomised into two groups. Group A received lornoxicam 8 mg and group B received diclofenac 75 mg intramuscularly twice daily for 3 consecutive days. The primary parameter was to analyse the postoperative pain using visual analogue scale (VAS) and Wong Bakers scale (WBS). The secondary parameters were the usage of rescue medication and time to use rescue medication. Results: There was a significant reduction in the postoperative pain in the lornoxicam group than the diclofenac group (p value
