a feasibility study

1,4

, Tai Strike1,4, Andrew Routh2, David Gaze3

1

4

Zoological Society of London

4

biomarker, cardiac pathology, cTnI, handheld analyser

OPEN ACCESS

Received: 11 September 2015 Accepted: 4 April 2016 Published online: 30 April 2016

health checks at the Zoological Society of London,

availability of equipment and a lack of recognised reference

provide a useful tool in the diagnosis and management of heart

for the assessment of myocardial damage in both humans and

tailed deer (Odocoileus virginianus

been suggested that the same assay used for humans and

Journal of Zoo and Aquarium Research 4(2) 2016

99

n Red billed toucan

1 1 Dendrocygna arborea

2

Cygnus atratus

1

Rockhopper penguin

2 1 1

bleeding of the coronary vessels at post-mortem

canine, feline and equine species, individual data from animals

Methods

Of these 22 mammals, 14 had

alaotrensis, one black-tailed silvery marmoset argentata, one meerkat Leptailurus serval

and one serval

Discussion

alkaline phosphatase and is captured onto the surface of the

cTnI above

Specialised equipment and anaesthesia is usually th

marker of cardiac pathology that can be measured at the pointa cornerstone in the diagnosis of cardiac disease in humans and

100

Journal of Zoo and Aquarium Research 4(2) 2016

cTnI range n

cTnI

Asian elephant Aye-aye

7

0

1

0

0

2

2

0

5

1

0

0

12

11

0

1

3

0

0

3

1

1

0

0

7

3

3

1

1

1

0

0

1

1

0

0

4

2

1

1

2

0

1

1

4

0

3

1

1

0

1

0

2

0

1

1

2

Alaotran gentle lemur

7 Sanguinus bicolor

1

Dasyprocta leporina

i

Hanuman langur

spp

Red-faced spider monkey Ring-tailed lemur

Serval

0

1

0

1

0

10

7

1

2

2

1

1

0

1

1

0

0

1

1

0

0

1

0

0

1

Nasua nasua

4

0

4

0

Leptailurus serval

1

0

0

1

1

1

0

0

2

1

0

1

1

1

0

0

2

1

1

0

Gorilla gorilla gorilla

persistent viral insult to the heart golden-headed lion tamarin ( )

) had a

Alaotran gentle lemurs troglodytes) undergoing a health

elephant (

Journal of Zoo and Aquarium Research 4(2) 2016

101

Individual samples th

n Asian elephant

1 virus

Aye-aye

2

Alaotran gentle lemur

5

1 3

1

Sudden cardiac death

1 1 1 Hanuman langur

spp

1 2

Ring-tailed lemur Serval

1 Leptailurus serval

1 1

histopathology) to have severe myocardial damage and cardiac )

of the coronary vessels on post-mortem Cygnus atratus also had undetectable

) and black-capped squirrel monkey ( boliviensis

diagnosis, prognosis and monitoring of cardiac disease in some of Odocoileus virginianus) validated

measurement may be useful in the assessment of cardiac damage cardiac pathology

102

cardiac troponin I analysers have not been standardised and because each vendor

Journal of Zoo and Aquarium Research 4(2) 2016

values obtained on one assay may not be directly comparable to

(2012) Longitudinal studies of cardiac

their approach to the assessment of cTn and if possible generate

10:

and skeletal muscle from various species in a cardiac troponin I

Clinical Cardiology 34: 723–

References

of Cardiology

herpesvirus-1 viremia in Asian elephants

endocrine and biochemical markers in childhood: establishment of pediatric reference intervals using healthy community children from

(Odocoileus virginianus

band in racing camels

46: troglodytes)

Care Clinical

Journal of Zoo and Aquarium Research 4(2) 2016

103