A study on relationship between elderly

European Journal of Medical Research

Bian et al. Eur J Med Res (2017) 22:25 DOI 10.1186/s40001-017-0266-9

Open Access

RESEARCH

A study on relationship between elderly sarcopenia and inflammatory factors IL‑6 and TNF‑α Ai‑Lin Bian*, Hui‑Ying Hu, Yu‑Dong Rong, Jian Wang, Jun‑Xiong Wang and Xin‑Zi Zhou

Abstract  Background:  This report aims to study the relationship between sarcopenia of elderly in community and inflamma‑ tory factors IL-6 and TNF-α. Methods:  A total of 441 elders who undertook physical examinations were included into this study. The age of these subjects were >60, in which 235 subjects were male and 206 subjects were female. According to the diagnostic standards of sarcopenia set by EWGSOP and AWGS, these subjects were divided into two groups: sarcopenia, and non-sarcopenia groups. The living habits, disease status, biochemical indexes, and levels of IL-6 and TNF-α of these subjects were investigated. Results:  The morbidity rate of sarcopenia was 17.02% in male subjects and 18.9% in female subjects. In elderly sub‑ jects >80 years old, morbidity rate was 25.3% in male subjects and 35.1% in female subjects. The history of smoking in patients with sarcopenia was long, and their regular exercise history was short (P