An open-source software framework for food safety ...

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platform (www.knime.org ). - scientific workflow management system ... repository, Wiki, File download (e.g.sample files), Ticket system. • Exchange of workflows ...
FEDERAL INSTITUTE FOR RISK ASSESSMENT

An open-source software framework for food safety analysis and modeling

Matthias Filter, Christian Thoens, Alexander Falenski, Bernd Appel, Annemarie Kaesbohrer, Armin A. Weiser Federal Institute for Risk Assessment (BfR), Germany

Outline: Motivation Introduction to PMM-Lab, FoodProcess-Lab, (FoodChain-Lab) Current work

Matthias Filter, 26 November 2014, EFFoST 2014 Uppsala

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Vision Food safety community resources (containing data, models, tools) supporting state-of-the-art risk assessments along the food chain

animal disease models

Food processing and distribution

Environmental factors

Matthias Filter, 26 November 2014, EFFoST 2014 Uppsala

human disease models

Processing parameters

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Current situation Plenty of predictive microbial models / risk assessment models published A number of predictive microbial / risk assessment software tools (ComBase Predictor, PMP, FSSP, MRV .... / FDA-iRISK, @Risk, R, rrisk …) A number of data, information and model repositories (ComBase, SymPrevius, GroPIN, ICRA, foodrisk.org …)

But • • • • • • •

NO integrated software tools for data management, model generation, scenario simulation and documentation Quality control in documentation of models / data still a major challenge NO harmonized file format for exchange of data / models / scenarios / simulations NO information exchange between predictive microbial modelling / risk assessment software tools FEW open-source software solutions FEW models implemented into tools (compared to number published) => Re-use of existing data, information and models HAMPERED

Matthias Filter, 26 November 2014, EFFoST 2014 Uppsala

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Conclusion Extension of

community resources in the field of food safety modeling needed •

Improve transparency, quality control and real information exchange with respect to data, models and the “art” of model generation



Support lab scientists / QM professionals to make use of their data and to contribute data and models to the community



Support standardization of data / model description and information exchange between tools



Support establishment of curated community model repositories

Matthias Filter, 26 November 2014, EFFoST 2014 Uppsala

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Open-source food-safety modeling framework

Tracing Analysis and Visualization

Predictive Microbiology

http://silebat.github.io/BfROpenLab

http://sourceforge.net/projects/pmmlab/

DB http://sourceforge.net/projects/foodprocesslab/

www.knime.org

Rind fleisch

Data Mining and Reporting

Matthias Filter, 26 November 2014, EFFoST 2014 Uppsala

Food Process Simulation

Nierenfett

Vorschneiden

Kuttern Froster Kuttern

Verpackungsmaterial

Füller Därme

Lager

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Verschweißen

Reiferaum

Raucherzeugung

What is KNIME (Konstanz Information Miner)?

- free, open source data integration and analysis platform (www.knime.org ) - scientific workflow management system - created and hosted by KNIME.com - community tool for data integration, transformation, modeling and visualization - Development framework for PMM-Lab, FoodProcess-Lab and FoodChain-Lab

Matthias Filter, 26 November 2014, EFFoST 2014 Uppsala

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PMM-Lab Predictive Microbiology Modeling-Lab

Matthias Filter, 26 November 2014, EFFoST 2014 Uppsala

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PMM-Lab – Database Integrated data management

Matthias Filter, 26 November 2014, EFFoST 2014 Uppsala

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PMM-Lab – Use case: model generation

Matthias Filter, 26 November 2014, EFFoST 2014 Uppsala

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PMM-Lab – Use case: predictions

Matthias Filter, 26 November 2014, EFFoST 2014 Uppsala

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FoodProcess-Lab Collection of information on food processing

Tetra Pak Handbuch der Milch- und Molkereitechnik, Gösta Bylund, 2003, Verlag Th. Mann GmbH & Co. KG

Matthias Filter, 26 November 2014, EFFoST 2014 Uppsala

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FoodProcess-Lab Design and run scenarios

Matthias Filter, 26 November 2014, EFFoST 2014 Uppsala

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Advantages of proposed software framework •

Free, open-source, transparent



Data management integrated (raw data, model generation process, estimated models, food process chains, scenario simulations)



Modular, highly flexible, easy-to-extend, easy-to-reuse



Integrated into KNIME (provides integration of „R“, MATLAB, Data mining, Report generation etc.)



Infrastructure for community contributions available: Code repository, Wiki, File download (e.g.sample files), Ticket system



Exchange of workflows -> sharing of knowledge with others

Matthias Filter, 26 November 2014, EFFoST 2014 Uppsala

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Current work Predictive Modeling in Food Markup Language (PMF-ML)

Glna Fit GlnaF it

Gro PIN FILT REX

FILT REX

DB DB GroP IN

FISH MAP

DB FISH MAP

Dairy Product Safety Predictor

Dairy Product Safety Predictor

=> Soon available at: http://sourceforge.net/projects/microbialmodelingexchange/ Matthias Filter, 26 November 2014, EFFoST 2014 Uppsala

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FEDERAL INSTITUTE FOR RISK ASSESSMENT

Thanks to the BfR team Armin A. Weiser, Christian Thöns, Alexander Falenski, Arvid Heise, Carolina Plaza-Rodriguez, Annemarie Käsbohrer, Bernd Appel

Thank you for your attention Matthias Filter Federal Institute for Risk Assessment Max-Dohrn-Str. 8-10

10589 Berlin, GERMANY

Tel. +49 30 - 184 12 - 2209

Fax +49 30 - 184 12 - 47 41

[email protected]

www.bfr.bund.de

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