Nov 18, 2014 - the groups other than group I daily at a dose of (500 mg/kg p.o.). ..... Khan, Department of Clinical Biochemistry, Shadan Institute of Medical ...
A Journal of the Bangladesh Pharmacological Society (BDPS); www.bdps.info Bangladesh J Pharmacol 2014; 9: 588-94 Journal homepage: www.banglajol.info Abstracted/indexed in Academic Search Complete, Agroforestry Abstracts, Asia Journals Online, Bangladesh Journals Online, Biological Abstracts, BIOSIS Previews, CAB Abstracts, Current Abstracts, Directory of Open Access Journals, EMBASE/Excerpta Medica, Google Scholar, HINARI (WHO), International Pharmaceutical Abstracts, Open J-gate, Science Citation Index Expanded, SCOPUS and Social Sciences Citation Index ISSN: 1991-0088; DOI: 10.3329/bjp.v9i4.20515
Amelioration of carbon tetrachloride- and paracetamol- induced hepatotoxicity in rats by Ficus dalhousiae Syed Safiullah Ghori1,3, Mohib Khan2 and Shaikh Abdul Rahman3 1
Department of Pharmacology, Himalayan University,Naharlagun, Itanagar, Arunachal Pradesh, India; 2Department of Pharmacognosy and Phytochemistry, Oriental College of Pharmacy, Sanpada (E), Navi Mumbai, India; 3 Department of Pharmacology & Pharmaceutical Chemistry, Anwarul Uloom College of Pharmacy, New Mallepally, Hyderabad 500001, Andhra Pradesh, India.
Article Info
Abstract
Received: 22 September 2014 Accepted: 7 October 2014 Available Online: 18 November 2014
The present study was undertaken to investigate hepatoprotective activity of Ficus dalhousiae leaves ethanolic extract based on its traditional claim. Paracetamol- and carbon tetrachloride-induced hepatotoxicity in albino Wistar rats, experimental models was used for the evaluation. Various biochemical parameters like SGPT, SGOT, serum albumin, alkaline phosphatase, total bilirubin, direct bilirubin and total protein were estimated. Oral treatment with the extract 250 and 500 mg/kg, significantly (p
