Dec 23, 2003 - Antioxidant and nitric oxide synthase activation properties of Auricularia auricula. Krishnendu Acharya*, Krishnendu Samui,. Manjula Rai, Bani ...
Indian Journal of Experimental Biology Vol. 42, May 2004, pp. 538-540
Antioxidant and nitric oxide synthase activation properties of Auricularia auricula Krishnendu Acharya*, Krishnendu Samui , Manjula Rai, Bani Brata Dutta & Rupa Acharya Biotechnology Researc h Laboratory, Post Graduate Department of Botany, Darjeeling Government College, Daljeeling 734 101 , Ind ia
Received 10 September 2003; revised 23 December 2003
III vitro evaluation of antioxidant acti vities of Auricularia I./uricula showed signifi cant inhibition of lipid peroxidation, and pote nt hydroxyl radical scavenging activity when compared with ;tamlard drug catechin. lC 50 value of crude, boiled and ethanolic -Principles and actions, edited by J Lancaster (Academic Pre~ " New York) 1996, 111. 8 Fledman P L, Griffith 0 W & Stuchr D J, The surprising life of nitric oxide, Chelll Eng News. 20 (1993) 26. 9 McDonald B, Reep P , Lapetina E G & Vedia L M, Glyceraldehyde-3-phosphate dehydrogenase is required for the transport of nitric oxide in platelets, Proc Natl Acad Sci, USA, 90 (1993) 11122. 10 Beckman J S, The physiological and pathological chemistry of nitric oxide. in Nitric Oxide. Principles and actions, edited by J Lancaster (Academic Press, New York) 1996, \. 11 Sinha A K, Acharya K, Bhattacharya S, Mazumder S, Bawmann A W & Kahn N N, Prevention of thrombosis in vivo by nitric oxide, Indian J Physiol Allied Sci, 52 (1998) 148. 12 Kahn N N, Acharya K, Bhattacharya S, Acharya R, Mazumder S, Bawmann A W & Sinha A K, Nitric oxide: The second messenger of insulin, IUBMB Life, 49 (2000) 441. 13 Ramsbottom J, A handbook of larget Britishfungi, (Alden & Mowbray Ltd, Great Britain) 1965. 14 HalIwelI B, Gutteridge J M L & Aruoma 0 I, The deoxyribose method: A sample test tube assay for determination of rate constants for reactions of hydroxyl radicals, Anal Biochem, 165 (1987) 215. 15 Buege J & Aust D S, Microsomal lipid peroxidation. in Methods in Enzymology, vol. 52, edited by S Flei sscher and L Packer, (Academic Press, New York) 1978,302. 16 Martin J P, Daiby M & Sugrman E, Negative and positive assays of superoxide dismutase based on hematoxilin autooxidation, Arch Biochelll Biophys, 208 (1987) 329. 17 Jia L, Bonaventua, C, Bonaventura J & Stamler S J, Snitrosohemoglobin: A dynamic activity of blood involved in vascular control, Nature, 380 (1996) 221. 18 Schmidt H H H W, Lohmann S M & Walter U, The nitric oxide and cGMP signal transduction system-regulation and mechanism of action, Biochim Biophys Acta, 1178 (1993) 153. 19 Sprague R S, Stephenson A H, Dimmitt R A, Branch C A, McMurado L & Lonigro A J, Inhibition of nitric oxide synthesis results in a selective increase in arterial resistance in rabbit lung, Pol J Pharmacol, 46 (1994) 579. 20 Acharya K, Samui K, Yon zone P & Mukherjee S, Nutritional composition of two medicinally importants mushrooms, Indian J Applied Pure Bioi, 17 (2002) 144. 4
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