Associations of plasma atrial natriuretic peptide and ...
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Associations of plasma atrial natriuretic peptide and ...
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EXPERIMENTAL AND THERAPEUTIC MEDICINE 5: 1439-1443, 2013
Associations of plasma atrial natriuretic peptide and electrolyte levels with essential hypertension GUANGMEI HU1, XINJUAN XU1,2, XIAOHUI LIANG1, XIAOPING YANG1, JUNSHI ZHANG1, ZHULEPIYA SIMAYI1 and YULAN CHEN1 1
State Key Laboratory Incubation Base of Xinjiang Major Diseases Research; First Affiliated Hospital of Xinjiang Medical University, Urumchi, Xinjiang 830054, P.R. China
2
Received November 19, 2012; Accepted January 22, 2013 DOI: 10.3892/etm.2013.991 Abstract. This study aimed to investigate the associations among the levels of plasma atrial natriuretic peptide (ANP) and electrolytes and essential hypertension (EH) in Uygur, Han and Kazakh populations in Xinjiang. A total of 724 hypertensive participants of different ethnicities from Xinjiang (208 Uygur, 287 Han and 229 Kazakh) and 741 normal controls (208 Uygur, 267 Han and 266 Kazakh) were enrolled. The associations of ANP with serum potassium, serum sodium and blood pressure were assessed. In the normal control (NT) group, the concentration of ANP was higher in the Uygur population than in the Han population, and the concentration in the Han population was higher than that in the Kazakh population (P