11/12/17, 9;04 PM. Abstract 15598: Brain Activity Within Regions Involved in Stress Percâ¦T/CT in a Resource-limited, Community-based Population | ...
Abstract 15598: Brain Activity Within Regions Involved in Stress Perc…T/CT in a Resource-limited, Community-based Population | Circulation
SCIENCE VOLUNTEER
WARNING SIGNS
Search
11/12/17, 9(04 PM
Advanced Search
DONATE
Hello, Guest!
Circulation HOME
ABOUT THIS JOURNAL
RESOURCES
ALL ISSUES
MY ALERTS
SUBJECTS
SIGN IN
JOIN
BROWSE FEATURES
AHA JOURNALS
Abstracts and presentations are embargoed for release at date and time of presentation or time of AHA/ASA news event. Failure to honor embargo policies (http://newsroom.heart.org/newsmedia/embargo-policy) will result in the abstract being withdrawn and barred from presentation. LIFESTYLE & BEHAVIORAL MEDICINE SESSION TITLE: CLINICAL RISK FACTORS AND BIOMARKERS IN RISK PREDICTION
Abstract 15598: Brain Activity Within Regions Involved in Stress Perception Associates Directly With Vascular Inflammation by 18-FDG PET/CT in a Resource-limited, Community-based Population Joshua P Rivers, Valerie Mitchell, Abhishek Chaturvedi, Aditya A Joshi, Amit K Dey, Faren Grant, Joel Adu-Brimpong, Samantha Thomas, Chaarushi Ahuja, Nehal N Mehta, Tiffany M Powell-Wiley
Circulation. 2017;136:A15598
Article
Info & Metrics
Abstract
http://circ.ahajournals.org/content/136/Suppl_1/A15598
This Issue Circulation November 1, 2017, Volume 136, Issue Suppl 1 Page 1 of 4
Abstract 15598: Brain Activity Within Regions Involved in Stress Perc…T/CT in a Resource-limited, Community-based Population | Circulation
Background: Psychosocial stress and depression correlate with cardiovascular (CV) events; however, association of objective physiologic measures of these psychological stressors with the development of CV disease is unclear. Thus, we examined the relationship between resting-state stress perception center activation, as measured by amygdala FDG uptake, and vascular inflammation (VI) by 18-FDG PET/CT in a resource-limited community-based (CB) cohort. Hypothesis: We hypothesized that amygdala activity by FDG uptake would directly associate with VI by 18-FDG PET/CT in a resource-limited CB cohort.
11/12/17, 9(04 PM
Table of Contents
Previous Article
Jump to Article Info & Metrics
Methods: Patients from the Washington, D.C. Cardiovascular Health and Needs Assessment, an assessment in predominantly African-American churches in resource-limited D.C. areas, underwent detailed phenotyping with cardiometabolic markers and whole-body 18-FDG PET/CT to measure VI and stress perception center activity (amygdala activity). Results: The cohort (N=31) was consecutively recruited, African American, middle-aged, and predominantly female (Table 1). These patients were obese, pre-hypertensive, and had abnormal lipid levels. In univariable analyses, VI significantly associated with sex, hypertension treatment, and CV disease risk by Framingham risk score (FRS) (p
