Carayol 2013 MASCC Supportive Care in Cancer suppl

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(66 %), by their relatives (50 %) or their regular doctor (37 %). Supportive care multi-professionnal meetings are held in 25 % of the institutes. The.
Support Care Cancer (2013) 21 (Suppl 1):S1–S301

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(66 %), by their relatives (50 %) or their regular doctor (37 %). Supportive care multi-professionnal meetings are held in 25 % of the institutes. The main participants are: doctors (96 %), psychologists (90 %), social workers (79 %), health managers (72 %), nurses (65 %), dietitians (65 %), junior doctors (62 %). 47 % of the institutes or departments have tools to evaluate the needs of supporting care. According to 56 % of the respondents, there are no specific case for supportive care in their department. 54 % of the respondents relate an efficient collaboration with home caregivers Conclusions: Interdisciplinarity is highly represented. Identification and coverage of the needs are provided by a set of participants. Supportive care meetings have to be developed, particularly for complex care where social workers help is needed. Coordination is underdeveloped: lack of evaluation tools, of traceability and of coordination within the departments. An AFSOS workgroup is studying the possibilities of organization and coordination of supportive care in and outside the hospital

MASCC-0532 A meta-analysis on the interest of exercise in adjuvant breast cancer patients: are the guidelines based on evidence? M. Carayol1, C. Delpierre2, G. Ninot1 1 Epsylon Laboratory EA4556, University of Montpellier, Montpellier, France, 2INSERM UMR 1027, Paul Sabatier University, Montpellier, France Introduction: Exercise has been recommended to relieve fatigue as category 1 in cancer patients with active treatment by the National Comprehensive Cancer Network [NCCN, 2011]. A recent meta-

Meta-regression β P-value Fatigue Intervention length (wk) No. of experiment patients Total targeted dose (MET.h) Journal Inpact factor Intent-to-treat analysis Quality-of-life Intervention length (wk) No. of experimental patients No. of sessions/week Intent-to-treat analysis Depression Intervention length (wk) Supervised exercise sessions (%) Individual exercise sessions Journal impact factor Intent-to-treat analusis Concealed randomization

analysis reported significant improvements on fatigue, depression and quality-of-life (QoL) in patients with exercise intervention compared to controls [Carayol et al., 2013]. However, significant amount of heterogeneity among pooled randomized controlled trials (RCTs) was observed, suggesting that some characteristics regarding study methodology and/or intervention may influence the effect of exercise interventions Objectives: To identify methodological and intervention factors that influence exercise efficacy on fatigue, QoL and depression in breast cancer patients receiving chemotherapy and/or radiotherapy Methods: RCTs testing exercise intervention were systematically identified. Characteristics regarding exercise intervention and methodological quality were coded and tested as moderators of exercise effect estimates in meta-regression models. Psychological outcomes summary effect sizes were then computed by pooling subgroup of RCTs based on categorized identified moderators. Results: Nineteen RCTs were included. Intervention length, use of intention-to-treat analysis and journal impact factor were significantly and negatively associated with exercise interventions efficacy on the improvement of psychological factors. Number of experimental patients was also negatively related to fatigue and QoL (P