Changes in ascending aorta dimensions, aortic valve function and ...
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Changes in ascending aorta dimensions, aortic valve function and systolic ventricular function over time in patients with congenital aortic stenosis Alexia Rossi*, Denise van der Linde, Tirza Springeling, Adriaan Moelker, Gabriel P Krestin, Robert J van Geuns, Jolien Roos-Hesselink From 2011 SCMR/Euro CMR Joint Scientific Sessions Nice, France. 3-6 February 2011 Introduction Bicuspid aortic valve (BAV) is one of the most common congenital heart malformations and is a frequent cause of aortic valve stenosis (AoS). Purpose The aim of this study was to evaluate the progression of aortic dilatation, aortic valve function, and ventricular function in patients with congenital AoS. Methods Twenty-five patients with congenital AoS were prospectively followed with ECG-gated cine-MRI. Aortic root and ascending aorta diameters were measured. Peak aortic velocity and mean gradient were assessed using a retrospectively gated phase contrast sequence. Left ventricular hemodynamic parameters and myocardial mass were calculated using steady-state free precession images. Results Sixteen men and 9 women were included in the study (mean age 32.6±7.6 years). The mean time (±SD) between baseline and follow-up study was 33.7±6.1 months. During follow-up aortic diameters significantly increased at aortic annulus by 1.4 mm (p=0.014), at sinus of Valsava by 2.0 mm (p=0.003) and at ascending aorta level by 2.0 mm (p
