Jan 2, 2002 - City University Graduate School of Medical Sciences, Nagoya, and .... GTC TAG ACT CGT GGT GGA CTT CTC TC ..... Genotypes, nt 1858.
JOURNAL OF VIROLOGY, June 2002, p. 6131–6137 0022-538X/02/$04.00⫹0 DOI: 10.1128/JVI.76.12.6131–6137.2002 Copyright © 2002, American Society for Microbiology. All Rights Reserved.
Vol. 76, No. 12
Characteristics of Hepatitis B Virus Isolates of Genotype G and Their Phylogenetic Differences from the Other Six Genotypes (A through F) Hideaki Kato,1,2 Etsuro Orito,1 Robert G. Gish,3 Fuminaka Sugauchi,1,2 Seiji Suzuki,1,2 Ryuzo Ueda,1 Yuzo Miyakawa,4 and Masashi Mizokami2* Department of Internal Medicine and Molecular Science1 and Department of Clinical Molecular Informative Medicine,2 Nagoya City University Graduate School of Medical Sciences, Nagoya, and Miyakawa Memorial Research Foundation, Tokyo,4 Japan, and Department of Hepatology and Gastroenterology, California Pacific Medical Center, San Francisco, California3 Received 2 January 2002/Accepted 14 March 2002
Eight hepatitis B virus (HBV) isolates of genotype G were recovered from patients and sequenced over the entire genome. Six of them had a genomic length of 3,248 bp and two had genomic lengths of 3,239 bp (USG15) and 3,113 bp (USG18) due to deletions. The 10 HBV/G isolates, including the 8 sequenced isolates as well as the original isolate (AF160501) and another isolate (B1-89), had a close sequence homology of 99.3 to 99.8% among themselves (excluding USG18 with a long deletion) but of
