Characterization of porcine simple sequence repeat ...

Characterization of porcine simple sequence repeat variation on a population scale with genome resequencing data Congcong Liu1, Yan Liu1, Xinyi Zhang1, Xuewen Xu1,2,*, Shuhong Zhao1,2 1

Key Lab of Agricultural Animal Genetics, Breeding, and Reproduction of the Ministry of Education &

Key Lab of Swine Genetics and Breeding of the Ministry of Agriculture, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, 430070 Hubei, PR China 2

The Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430070, China

*Corresponding author Contact information Xuewen Xu College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, 430070 Hubei, China Tel.: +86 27 87388470 Fax: +86 27 87280408 Email: [email protected]

Supplementary Table S1. Distribution of each kind of SSRs in pig genome. Chromosome 1 1 1 1 1 2 2 2 2 2 3 3 3 3 3 4 4 4 4 4 5 5 5 5 5 6 6 6 6 6 7 7 7 7 7 8 8 8 8 8 9 9 9 9 9 10 10 10 10 10 11 11 11

SSR Type SSR Count Dinucleotide 46900 Trinucleotide 24229 Tetranucleotide 59311 Pentanucleotide 33042 Hexanucleotide 24604 Dinucleotide 24529 Trinucleotide 13209 Tetranucleotide 32234 Pentanucleotide 17750 Hexanucleotide 14319 Dinucleotide 22044 Trinucleotide 12165 Tetranucleotide 29068 Pentanucleotide 15995 Hexanucleotide 13973 Dinucleotide 21996 Trinucleotide 11723 Tetranucleotide 28391 Pentanucleotide 15629 Hexanucleotide 12503 Dinucleotide 16763 Trinucleotide 9472 Tetranucleotide 21750 Pentanucleotide 12238 Hexanucleotide 9637 Dinucleotide 23181 Trinucleotide 13657 Tetranucleotide 31856 Pentanucleotide 17490 Hexanucleotide 15072 Dinucleotide 20227 Trinucleotide 11504 Tetranucleotide 26943 Pentanucleotide 15119 Hexanucleotide 12704 Dinucleotide 23586 Trinucleotide 11493 Tetranucleotide 28623 Pentanucleotide 15801 Hexanucleotide 12250 Dinucleotide 23709 Trinucleotide 12367 Tetranucleotide 29440 Pentanucleotide 16485 Hexanucleotide 12236 Dinucleotide 12618 Trinucleotide 6558 Tetranucleotide 15955 Pentanucleotide 8909 Hexanucleotide 8056 Dinucleotide 13576 Trinucleotide 6827 Tetranucleotide 16851

Count/Mbp Density(bp/Mbp) 148.737 2997.076 76.839 1397.803 188.097 3771.753 104.788 2147.679 78.028 1816.823 150.883 3033.646 81.251 1473.586 198.278 3981.715 109.184 2232.395 88.079 2053.246 152.251 3095.955 84.02 1533.719 200.763 4109.849 110.472 2291.319 96.507 2270.33 153.319 3114.725 81.713 1476.803 197.894 3995.345 108.939 2261.645 87.15 2030.092 150.332 3005.988 84.946 1542.53 195.056 3908.16 109.752 2252.247 86.426 2007.274 146.933 2981.474 86.565 1593.776 201.92 4130.349 110.861 2284.522 95.534 2230.607 150.091 3051.575 85.364 1560.344 199.927 4047.757 112.188 2326.458 94.268 2203.028 158.837 3233.538 77.398 1414.933 192.758 3883.46 106.41 2203.098 82.496 1927.756 154.285 3109.822 80.478 1466.042 191.579 3794.522 107.275 2189.501 79.625 1875.569 159.515 3281.798 82.905 1509.854 201.701 4151.961 112.626 2330.904 101.843 2406.97 154.817 3111.965 77.853 1420.837 192.164 3893.714

11 11 12 12 12 12 12 13 13 13 13 13 14 14 14 14 14 15 15 15 15 15 16 16 16 16 16 17 17 17 17 17 18 18 18 18 18 X X X X X Y Y Y Y Y All All All All All

Pentanucleotide Hexanucleotide Dinucleotide Trinucleotide Tetranucleotide Pentanucleotide Hexanucleotide Dinucleotide Trinucleotide Tetranucleotide Pentanucleotide Hexanucleotide Dinucleotide Trinucleotide Tetranucleotide Pentanucleotide Hexanucleotide Dinucleotide Trinucleotide Tetranucleotide Pentanucleotide Hexanucleotide Dinucleotide Trinucleotide Tetranucleotide Pentanucleotide Hexanucleotide Dinucleotide Trinucleotide Tetranucleotide Pentanucleotide Hexanucleotide Dinucleotide Trinucleotide Tetranucleotide Pentanucleotide Hexanucleotide Dinucleotide Trinucleotide Tetranucleotide Pentanucleotide Hexanucleotide Dinucleotide Trinucleotide Tetranucleotide Pentanucleotide Hexanucleotide Dinucleotide Trinucleotide Tetranucleotide Pentanucleotide Hexanucleotide

9272 7488 9015 5990 13282 7586 7058 33032 16782 42751 23367 17311 23893 13315 31416 17150 14146 24274 11872 30296 16773 12422 13865 6755 16625 9178 6774 10542 5778 14511 7895 6642 9373 5035 11533 6529 5600 22613 11096 26716 14991 12369 207 144 315 181 144 395943 209971 507867 281380 225308

105.735 85.391 141.771 94.199 208.874 119.298 110.995 151.083 76.758 195.536 106.877 79.178 155.299 86.544 204.196 111.471 91.946 153.943 75.291 192.134 106.373 78.779 159.553 77.734 191.314 105.617 77.953 151.245 82.896 208.188 113.269 95.292 153.103 82.244 188.386 106.648 91.473 156.721 76.902 185.157 103.896 85.724 126.396 87.927 192.341 110.52 87.927 152.483 80.863 195.586 108.363 86.769

2164.736 1981.148 2811.622 1714.836 4145.336 2448.144 2583.672 3031.648 1385.495 3930.711 2207.023 1837.952 3171.893 1593.122 4136.288 2287.459 2139.394 3129.198 1363.038 3906.01 2196.255 1821.455 3248.197 1420.592 3846.443 2158.61 1815.74 3141.464 1537.713 4371.723 2360.406 2233.45 3033.401 1561.106 3662.377 2176.214 2135.231 3250.66 1439.14 3725.703 2135.691 1999.193 2383.808 1599.789 4142.965 2308.703 2430.824 3089.982 1477.24 3947.496 2230.945 2024.533

Supplementary Table S2. Distribution of SSRs in different genomic regions. unit length 2 2 2 2 2 2 2 3 3 3 3 3 3 3 4 4 4 4 4 4 4 5 5 5 5 5 5 5 6 6 6 6 6 6 6 all all all all all all all

feature 3'utr 5'utr cds exon intron promoter intergenic 3'utr 5'utr cds exon intron promoter intergenic 3'utr 5'utr cds exon intron promoter intergenic 3'utr 5'utr cds exon intron promoter intergenic 3'utr 5'utr cds exon intron promoter intergenic 3'utr 5'utr cds exon intron promoter intergenic

count 1971 354 845 238 115445 8901 295353 1011 1485 6832 312 65568 6452 145963 2153 719 1470 212 159129 12208 368982 1616 740 1333 183 89952 8091 200977 1046 392 2045 145 76767 6082 157203 7797 3690 12525 1090 506861 41734 1168478

count/Mb length length/Mb 146.447 37085 2755.445 122.389 6409 2215.788 26.083 11397 351.794 122.989 5740 2966.203 153.526 2273707 3023.714 159.578 176721 3168.263 154.093 6046489 3154.604 75.118 17745 1318.468 513.41 30788 10644.356 210.885 131087 4046.291 161.229 6371 3292.278 87.196 1185662 1576.766 115.672 121658 2181.09 76.153 2667311 1391.602 159.97 37031 2751.433 248.58 12413 4291.555 45.375 23956 739.455 109.553 3963 2047.92 211.619 3121794 4151.552 218.866 240685 4315.012 192.507 7533565 3930.448 120.07 30652 2277.468 255.841 15136 5232.979 41.146 23705 731.707 94.567 3408 1761.118 119.624 1835760 2441.306 145.056 164774 2954.076 104.855 4158150 2169.41 77.719 23363 1735.889 135.526 9180 3173.807 63.123 49450 1526.384 74.93 3670 1896.509 102.089 1775897 2361.696 109.038 142212 2549.584 82.017 3677799 1918.799 579.323 145876 10838.702 1275.746 73926 25558.485 386.612 239595 7395.632 563.268 23152 11964.029 674.055 10192820 13555.034 748.209 846050 15168.025 609.624 24083314 12564.864

Supplementary Table S3. Information of 102 individuals. Run SRR1004277 SRR1004278 SRR1004279 ERR173171 ERR173172 ERR173173 ERR173174 ERR173175 ERR173179 SRR652374 SRR652375 SRR652376 ERR173180 ERR173181 ERR173182 ERR173183 ERR173184 ERR173185 ERR173186 ERR173187 ERR173188 ERR173189 ERR173191 ERR173192 ERR173193 ERR173194 ERR173195 ERR173196 ERR173197 ERR173198 SRR1178916 SRR1178923 SRR1178925 ERR173199 ERR173200 ERR173201 ERR173202 SRR652357 SRR652363 SRR652348 SRR652350 ERR173204 ERR173205 ERR173206 ERR173207 ERR173208 ERR173209 ERR173211 SRR652258 SRR652264 SRR652343 SRR652344 SRR652345 SRR652346 SRR652347 SRR652262 SRR652265 SRR652327 SRR652339 SRR652340 SRR652341 SRR652342

Bases 13.4G 11.5G 11.4G 23.5G 12.3G 15.4G 23.4G 20.6G 21.4G 11.6G 12.4G 10.6G 19G 28.1G 18.4G 15.1G 15.5G 11.2G 20.8G 20.8G 20.8G 19.2G 19.5G 20.9G 20.3G 17.3G 18G 19.2G 17.5G 17.6G 40.9G 63.2G 41.8G 18.9G 18.8G 17.9G 20.8G 15.7G 11.4G 11.8G 14.1G 21.4G 21.7G 17.2G 11.3G 22.7G 20.2G 25.9G 12.2G 11.8G 11.5G 18.6G 14.5G 18.5G 15.1G 16G 17.6G 15.6G 12G 12.9G 12.5G 11.7G

Study SRP030626 SRP030626 SRP030626 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 SRP018123 SRP018123 SRP018123 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 SRP039012 SRP039012 SRP039012 ERP001813 ERP001813 ERP001813 ERP001813 SRP018123 SRP018123 SRP018123 SRP018123 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 SRP018123 SRP018123 SRP018123 SRP018123 SRP018123 SRP018123 SRP018123 SRP018123 SRP018123 SRP018123 SRP018123 SRP018123 SRP018123 SRP018123

BioSample SAMN02364505 SAMN02364506 SAMN02364507 SAMEA1557419 SAMEA1557423 SAMEA1557434 SAMEA1557391 SAMEA1557400 SAMEA1557388 SAMN01894455 SAMN01894456 SAMN01894457 SAMEA1557405 SAMEA1557416 SAMEA1557426 SAMEA1557436 SAMEA1557390 SAMEA1557412 SAMEA1557415 SAMEA1557431 SAMEA1557413 SAMEA1557402 SAMEA1557435 SAMEA1557422 SAMEA1557406 SAMEA1557404 SAMEA1557383 SAMEA1557425 SAMEA1557427 SAMEA1557399 SAMN02665306 SAMN02665304 SAMN02665305 SAMEA1557420 SAMEA1557428 SAMEA1557395 SAMEA1557410 SAMN01894447 SAMN01894452 SAMN01894438 SAMN01894440 SAMEA1557430 SAMEA1557432 SAMEA1557392 SAMEA1557408 SAMEA1557397 SAMEA1557409 SAMEA1557384 SAMN01894346 SAMN01894369 SAMN01894412 SAMN01894434 SAMN01894435 SAMN01894436 SAMN01894437 SAMN01894367 SAMN01894370 SAMN01894407 SAMN01894408 SAMN01894409 SAMN01894410 SAMN01894411

Breed Berkshire Berkshire Berkshire Duroc Duroc Duroc Hampshire Hampshire Jiangquhai Jinhua Jinhua Jinhua Landrace Landrace Landrace Landrace Landrace LargeWhite LargeWhite LargeWhite LargeWhite LargeWhite LargeWhite LargeWhite LargeWhite LargeWhite LargeWhite LargeWhite LargeWhite LargeWhite mangalica mangalica mangalica Meishan Meishan Meishan Meishan Neijiang Neijiang Penzhou Penzhou Pietrain Pietrain Pietrain Pietrain Pietrain SusCebifrons SusVerrucosus Tibetan Tibetan TibetanABa TibetanABa TibetanABa TibetanABa TibetanABa TibetanDiqing TibetanDiqing TibetanGannan TibetanGannan TibetanGannan TibetanGannan TibetanGannan

SRR652257 SRR652259 SRR652260 SRR652261 SRR652267 SRR652268 SRR652269 SRR652270 SRR652302 SRR652303 SRR652304 SRR652305 SRR652306 SRR652307 SRR1172563 SRR1172577 SRR1216635 SRR1216636 ERR173217 ERR173212 ERR173215 ERR173216 ERR173213 ERR173214 ERR173221 ERR173222 ERR173219 ERR173220 SRR652377 SRR652378 SRR652379 ERR173218 SRR652351 SRR652352 SRR652353 ERR173223 ERR173224 SRR652354 SRR652355 SRR652356

12G 10.6G 14.3G 14.2G 9.8G 19G 13.4G 12.2G 17.9G 14.7G 11.5G 15G 12.4G 14.9G 22.5G 24.4G 17.5G 16.6G 19.2G 22.5G 10.9G 16.3G 18.8G 23.5G 9.8G 20.2G 10.3G 20.8G 12G 16.3G 16.3G 29.4G 15.9G 14.2G 12G 18.4G 18.1G 12.1G 11.1G 13.1G

SRP018123 SRP018123 SRP018123 SRP018123 SRP018123 SRP018123 SRP018123 SRP018123 SRP018123 SRP018123 SRP018123 SRP018123 SRP018123 SRP018123 SRP038221 SRP038221 SRP038221 SRP038221 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 ERP001813 SRP018123 SRP018123 SRP018123 ERP001813 SRP018123 SRP018123 SRP018123 ERP001813 ERP001813 SRP018123 SRP018123 SRP018123

SAMN01894345 SAMN01894349 SAMN01894360 SAMN01894361 SAMN01894387 SAMN01894388 SAMN01894389 SAMN01894390 SAMN01894391 SAMN01894392 SAMN01894393 SAMN01894394 SAMN01894395 SAMN01894406 SAMN02646543 SAMN02646545 SAMN02646544 SAMN02646546 SAMEA1557401 SAMEA1557411 SAMEA1557394 SAMEA1557387 SAMEA1557424 SAMEA1557433 SAMEA1557437 SAMEA1557421 SAMEA1557386 SAMEA1557396 SAMN01894458 SAMN01894459 SAMN01894460 SAMEA1557403 SAMN01894441 SAMN01894442 SAMN01894443 SAMEA1557398 SAMEA1557385 SAMN01894444 SAMN01894445 SAMN01894446

TibetanGanzi TibetanGanzi TibetanGanzi TibetanGanzi TibetanNyingchi TibetanNyingchi TibetanNyingchi TibetanNyingchi TibetanNyingchi TibetanShigatse TibetanShigatse TibetanShigatse TibetanShigatse TibetanShigatse Tongcheng Tongcheng Tongcheng Tongcheng WildBoarFrance WildBoarJapan WildBoarNetherlandsMeinweg WildBoarNetherlandsMeinweg WildBoarNetherlandsVeluwe WildBoarNetherlandsVeluwe WildBoarNorthChina WildBoarNorthChina WildboarSouthChina WildBoarSouthChina WildBoarSouthChina WildBoarSouthChina WildBoarSouthChina WildBoarSwitzerlandMalcantone Wujin Wujin Wujin Xiang Xiang Yanan Yanan Yanan

Supplementary Table S4. Information of polymorphic SSRs. motif chromosome AC.GT 1 AC.GT 1 AC.GT 1 AAAAG.CTTTT 1 AAAAC.GTTTT 1 AG.CT 1 AC.GT 1 ACAG.CTGT 1 AC.GT 1 AAAT.ATTT 1 AAC.GTT 1 AAAT.ATTT 1 AAAC.GTTT 1 AG.CT 1 AT.AT 1 AAAAC.GTTTT 1 AC.GT 1 AAAC.GTTT 1 AAAC.GTTT 1 AC.GT 1 AAT.ATT 1 AAAT.ATTT 1 AAAC.GTTT 1 AG.CT 1 AAAAT.ATTTT 1 AC.GT 1 AAAAC.GTTTT 1 ACAT.ATGT 1 AGC.GCT 1 AC.GT 1 AC.GT 1 AAGG.CCTT 1 AT.AT 1 AAAAC.GTTTT 1 AATG.CATT 1 AAAGG.CCTTT 1 AAAAC.GTTTT 1 AAAC.GTTT 1 AAAC.GTTT 1 AAAC.GTTT 1 AAG.CTT 1 AC.GT 1 AG.CT 1 AAAC.GTTT 1 AAC.GTT 1 AC.GT 1 AC.GT 1 AAG.CTT 1 AAAT.ATTT 1 AC.GT 1 AG.CT 1 ATC.GAT 1 AAGC.GCTT 1 AAAAAC.GTTTTT 1 AC.GT 1 AAAAC.GTTTT 1 AAAAC.GTTTT 1 AC.GT 1 AC.GT 1 AAAT.ATTT 1 AAAT.ATTT 1 AC.GT 1 AAC.GTT 1 AAAG.CTTT 1 AAAC.GTTT 1 AC.GT 1 AAAAAC.GTTTTT 1 AT.AT 1 AAAAC.GTTTT 1 AC.GT 1 AT.AT 1 AT.AT 1 AAAC.GTTT 1 AAT.ATT 1 AG.CT 1 AG.CT 1 AC.GT 1 AAAAC.GTTTT 1 AG.CT 1 AT.AT 1 AAAAAG.CTTTTT 1 AC.GT 1 AC.GT 1

start 1084452 1084452 1969878 2874375 3226034 4062541 4336676 4883530 5054068 6199497 6344042 6600847 6603990 6775793 6887154 6975470 7131330 7302256 7317717 7494020 7500466 7537649 7711651 7841421 7966978 7968585 8390257 8410522 8517259 8829617 9540541 9555317 9656766 9842832 9931936 9995403 10140516 10201654 10652559 10762186 11460374 11553654 11671921 11713500 11742438 11922585 12403704 12611170 12627427 12666645 12960924 13437854 13495642 13599074 13613107 13697925 13697925 13700410 13700410 13791250 14407955 14600614 14623134 14896538 14928503 15405845 15519417 15564918 15580047 15730042 15811346 16037898 16043276 16106484 16168442 16168442 16243125 16407160 16522300 16954338 17064141 17125793 17125793

end ref repeat 1084463 6 1084463 6 1969899 11 2874390 3.2 3226057 4.8 4062553 6.5 4336697 11 4883563 8.5 5054086 9.5 6199513 4.25 6344055 4.66667 6600862 4 6604006 4.25 6775814 11 6887167 7 6975501 6.4 7131362 16.5 7302284 7.25 7317738 5.5 7494032 6.5 7500483 6 7537666 4.5 7711665 3.75 7841430 5 7966992 3 7968610 13 8390276 4 8410536 3.75 8517276 6 8829630 7 9540555 7.5 9555342 6.5 9656775 5 9842857 5.2 9931959 6 9995419 3.4 10140533 3.6 10201677 6 10652572 3.5 10762204 4.75 11460392 6.33333 11553668 7.5 11671931 5.5 11713515 4 11742451 4.66667 11922604 10 12403725 11 12611183 4.66667 12627439 3.25 12666680 18 12960936 6.5 13437869 5.33333 13495664 5.75 13599091 3 13613119 6.5 13697948 4.8 13697948 4.8 13700420 5.5 13700420 5.5 13791270 5.25 14407973 4.75 14600627 7 14623147 4.66667 14896549 3 14928516 3.5 15405859 7.5 15519443 4.5 15564941 12 15580070 4.8 15730053 6 15811364 9.5 16037909 6 16043290 3.75 16106503 6.66667 16168455 7 16168455 7 16243136 6 16407182 4.6 16522309 5 16954351 7 17064166 4.33333 17125812 10 17125812 10

transcript id ENSSSCT00000004431 ENSSSCT00000004434 . . . . . . . . . . . . . . . ENSSSCT00000004459 ENSSSCT00000004459 ENSSSCT00000004459 ENSSSCT00000004459 ENSSSCT00000004459 ENSSSCT00000004459 . . . ENSSSCT00000004461 ENSSSCT00000004461 ENSSSCT00000004465 ENSSSCT00000004467 . . . ENSSSCT00000004480 . . ENSSSCT00000004483 . . ENSSSCT00000027733 . . . ENSSSCT00000004492 ENSSSCT00000004492 . . . . . . . . ENSSSCT00000031943 ENSSSCT00000031943 ENSSSCT00000004494 ENSSSCT00000027128 ENSSSCT00000004494 ENSSSCT00000027128 . ENSSSCT00000004500 ENSSSCT00000004501 . . . . . . . . . . . ENSSSCT00000004510 ENSSSCT00000004510 ENSSSCT00000030512 . ENSSSCT00000004511 . . . ENSSSCT00000004518 ENSSSCT00000030322

alleles gene name feature conservation dbSNP WDR27 intron -0.432 . 3 ERMARD intron -0.432 . 3 . intergenic . rs788463500 4 . intergenic 0.134 602872 rs7888 2 . intergenic -0.132 . 4 . intergenic -0.332 rs791046496 2 . intergenic -0.303 rs792187070 2 . intergenic -0.032 rs790720923 2 . intergenic -0.235 rs792589336 2 . intergenic . rs790148838 2 . intergenic . rs706466330 2 . intergenic -0.749 rs788323413 2 . intergenic -0.032 889601 rs7893 2 . intergenic -0.211 355022 rs7902 4 . intergenic 0.147 750062 rs7863 3 . intergenic 0.207 rs788965134 2 . intergenic -0.023 rs702403861 3 PARK2 intron 0.165 943149 rs7871 2 PARK2 intron -0.268 580533 rs7878 2 PARK2 intron . rs787554650 3 PARK2 intron 0.017 rs789938892 2 PARK2 intron -0.607 rs790609900 2 PARK2 intron . 703991 rs7932 2 . intergenic -0.132 rs697031563 2 . intergenic . rs791064598 2 . intergenic 0.018 842666 rs7885 2 AGPAT4 intron -0.069 rs786341973 2 AGPAT4 intron -0.036 rs793406062 2 . intron -0.465 rs793698502 2 SLC22A3 intron -0.075 rs790865956 2 . intergenic . rs792066398 2 . intergenic -0.011 rs793646991 2 . intergenic -0.004 rs697943185 2 FNDC1 intron -0.125 rs789382973 2 . intergenic -0.174 rs789660373 2 . intergenic -0.107 rs790741907 2 RSPH3 intron . rs787080539 2 . intergenic 0.198 981079 rs7896 2 . intergenic . rs786371742 2 . intron . . 2 . intergenic -0.223 rs791901651 2 . intergenic -0.039 . 2 . intergenic . . 2 . intron 0.215 rs789509937 2 . intron . rs790544711 2 . intergenic . . 4 . intergenic 0.31 rs789806900 2 . intergenic -0.028 rs791506100 2 . intergenic 0.048 rs791486872 2 . intergenic 0.164 101909 rs7934 2 . intergenic 0.124 rs703979254 5 . intergenic 0.185 rs790889517 2 . intergenic . 066385 rs7894 2 TFB1M intron . 690558 rs7917 2 TFB1M intron -0.067 403028 rs7885 2 TIAM2 intron -0.2 rs787491324 2 TIAM2 intron -0.2 rs787491324 2 TIAM2 intron -0.1 . 3 TIAM2 intron -0.1 . 3 . intergenic . . 2 . intron 0.247 rs788683343 2 . intron 0 rs793563016 2 . intergenic -0.119 527592 rs7892 5 . intergenic -0.021 . 2 . intergenic 0.028 rs792568041 2 . intergenic . 802227 rs7870 2 . intergenic -0.061 rs692048080 2 . intergenic 0.537 465066 rs7899 2 . intergenic 0.181 rs791463609 2 . intergenic . . 2 . intergenic 0.12 rs793636148 2 . intergenic -0.133 233206 rs7886 2 . intergenic 0.074 545834 rs7894 2 . intron 0.052 rs690406510 2 . intron -0.009 994057 rs7025 6 . intron -0.009 994057 rs7025 6 . intergenic 0.38 rs699214597 3 . intron -0.279 765270 rs7924 2 . intergenic . rs793887413 2 . intergenic . 129803 rs7864 2 . intergenic -0.014 508143 rs7918 2 CCDC170 intron 0.201 . 2 CCDC170 intron 0.201 . 2

AAATG.CATTT AT.AT AAATG.CATTT AC.GT AAAC.GTTT AAC.GTT AT.AT AC.GT AAAAAC.GTTTTT AC.GT AAAAT.ATTTT AAAC.GTTT AAAT.ATTT AC.GT AC.GT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AAAC.GTTT AAAT.ATTT AAAC.GTTT AAAG.CTTT AT.AT AAAAT.ATTTT AAT.ATT AT.AT AT.AT AAAT.ATTT AG.CT AAAC.GTTT AC.GT AAAC.GTTT AAC.GTT AAAT.ATTT AT.AT AT.AT AAC.GTT AAT.ATT AG.CT AC.GT AAAC.GTTT AAC.GTT AC.GT AAC.GTT AT.AT AC.GT AC.GT AAAG.CTTT AG.CT AAAAC.GTTTT AT.AT AAAC.GTTT AT.AT AAAC.GTTT AAT.ATT AAAT.ATTT AC.GT AC.GT AC.GT AAAG.CTTT AT.AT AT.AT AAC.GTT AG.CT AT.AT AAAC.GTTT AC.GT AG.CT AT.AT AG.CT AAG.CTT ATC.GAT AAG.CTT AAG.CTT AAAC.GTTT AT.AT AAAC.GTTT AGC.GCT AC.GT AAAT.ATTT AAAG.CTTT AT.AT AAC.GTT

1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

17190714 17229949 17234709 17247561 17252969 17347418 17495488 17796962 17915438 17916678 18035005 18085891 18193220 18491402 18513426 18580440 18677125 18677125 19290976 19333443 19528921 19833214 20078640 20307776 20409587 20511284 20619863 20828987 20921656 21268672 21500670 21532888 21542962 21700070 21742006 21778438 21913731 21951985 22044955 22056323 22192928 22218097 22359082 22974449 22985964 23021299 23277319 23456794 23476616 24048324 24066376 24086598 24454377 24457904 25210781 25572131 25814878 26089473 26292786 26440793 26610706 26832123 26958549 27308104 27348221 27376830 27580717 27604864 27705511 27835615 27871328 27881079 28304800 28727401 28727401 28767210 28773510 28894274 28948150 29013044 29034708 29084804 29087476 29097477

17190734 17229964 17234727 17247570 17252987 17347431 17495500 17796983 17915457 17916689 18035027 18085906 18193234 18491426 18513440 18580468 18677140 18677140 19290999 19333460 19528945 19833239 20078662 20307807 20409601 20511298 20619873 20829001 20921684 21268694 21500688 21532920 21542978 21700084 21742026 21778448 21913741 21952007 22044969 22056338 22192940 22218121 22359100 22974468 22985980 23021309 23277345 23456806 23476641 24048333 24066394 24086612 24454397 24457924 25210795 25572151 25814895 26089501 26292796 26440805 26610724 26832132 26958582 27308123 27348231 27376847 27580745 27604877 27705521 27835624 27871337 27881096 28304821 28727418 28727418 28767228 28773536 28894292 28948167 29013054 29034731 29084831 29087513 29097490

4.2 8 3.8 5 4.75 4.66667 6.5 11 3.33333 6 4.6 4 3.75 12.5 7.5 5.8 4 4 4.8 4.5 6.25 6.5 5.75 16 3 5 5.5 7.5 7.25 11.5 4.75 16.5 4.25 5 5.25 5.5 5.5 7.66667 5 8 6.5 6.25 6.33333 10 5.66667 5.5 13.5 6.5 6.5 5 3.8 7.5 5.25 10.5 3.75 7 4.5 14.5 5.5 6.5 4.75 5 17 6.66667 5.5 9 7.25 7 5.5 5 5 6 7.33333 6 6 4.75 13.5 4.75 6 5.5 6 7 19 4.66667

ENSSSCT00000004519 C6orf211 3'utr ENSSSCT00000004520 RMND1 intron ENSSSCT00000004520 RMND1 intron ENSSSCT00000004520 RMND1 intron ENSSSCT00000004520 RMND1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000004526 PPP1R14C intron . . intergenic . . intergenic ENSSSCT00000004536 LRP11 intron ENSSSCT00000004536 LRP11 intron ENSSSCT00000004540 NUP43 intron ENSSSCT00000023948 . intron ENSSSCT00000024741 PPIL4 intron . . intergenic ENSSSCT00000024450 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000004548 . intron . . intergenic . . intergenic . . intergenic ENSSSCT00000004554 GRM1 intron ENSSSCT00000004554 GRM1 intron ENSSSCT00000004554 GRM1 intron ENSSSCT00000004554 GRM1 intron ENSSSCT00000004554 GRM1 intron ENSSSCT00000004554 GRM1 intron ENSSSCT00000004555 SHPRH intron . . intergenic . . intergenic ENSSSCT00000004557 EPM2A intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000004558 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000004576 NMBR intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000004583 ECT2L intron ENSSSCT00000023305 ECT2L intron ENSSSCT00000004583 ECT2L promoter . . intergenic ENSSSCT00000004585 NHSL1 intron ENSSSCT00000004585 NHSL1 intron ENSSSCT00000004585 NHSL1 intron ENSSSCT00000004585 NHSL1 intron ENSSSCT00000004585 NHSL1 intron ENSSSCT00000004585 NHSL1 intron ENSSSCT00000004585 NHSL1 intron

0.311 0.058 -0.251 -0.021 . 0.251 -0.187 . 0.231 . -0.083 -0.096 . . 0.166 0.13 4.141 4.141 -0.059 -0.315 0.109 . 0.149 0.083 . 0.027 . . -0.034 -0.001 -0.067 0.332 . 0.084 0.206 0.068 0.068 . 0.141 0.127 0.006 . 0.22 0.025 0.065 0.086 0.007 . 0.14 . . 0.202 -0.157 -0.039 0.084 -0.01 -0.043 . 0.172 -0.099 -0.02 0.115 0.067 0.022 0.09 -0.256 -0.137 1.286 -0.118 0.056 0.207 0.174 -0.022 -0.067 -0.067 0.057 0.003 0.196 -0.389 0.189 0.028 . 0.154 0.172

474168 rs7910 rs707573049 471975 rs7913 rs789218113 rs790570326 rs693832947 497810 rs7882 rs790238141 rs792853253 rs790410673 rs790941110 rs793875210 rs790840692 183637 rs7053 rs786633528 rs792767079 rs787759203 rs787759203 rs787645188 . rs788127697 123306 rs7937 rs788232476 rs787681869 rs788275668 . rs792095552 rs786808095 rs788394548 rs792573785 rs790826708 690770 rs7874 rs792676375 rs793139146 rs787679935 . . . rs791863290 rs787195960 rs788252448 428732 rs7927 rs792767503 201761 rs7892 rs789724657 rs791010547 rs787716774 rs791239132 046967 rs7874 rs706863033 . 926209 rs7902 rs788971360 rs790840906 rs788312525 rs788738300 . rs793098374 . 538694 rs7912 rs789844007 . 043435 rs7882 . 177742 rs7875 rs786224763 rs788389829 266483 rs7868 . rs787806904 rs789872320 088913 rs7901 rs693039343 346615 rs7900 346615 rs7900 rs787937088 684548 rs7876 740607 rs7890 687813 rs7880 rs791549308 798660 rs7879 235900 rs7876 rs787786393 rs792277197

2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 3 2 2 2 4 2 2 2 3 2 2 2 2 4 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 3 3 2 3 2 2 2 2 2 2 2 2 2 4 4 2 2 2 2 2 2

AGAT.ATCT AAT.ATT AG.CT AT.AT AG.CT AG.CT AT.AT AAT.ATT AAT.ATT AAC.GTT AAAT.ATTT AAC.GTT AG.CT AAAC.GTTT AC.GT AC.GT AC.GT AAAAT.ATTTT AC.GT AAAG.CTTT AAAG.CTTT AC.GT AG.CT AT.AT AAAT.ATTT AAAT.ATTT AC.GT AAAC.GTTT AT.AT AC.GT AG.CT AC.GT AAC.GTT AC.GT AG.CT AT.AT AAAAC.GTTTT AAAAC.GTTTT AT.AT AC.GT AAC.GTT AAC.GTT AAAG.CTTT AAAAAC.GTTTTT AAAAC.GTTTT AG.CT AC.GT AG.CT AAAAT.ATTTT AC.GT AC.GT AC.GT AG.CT AAAC.GTTT ACCC.GGGT ACATAT.ATATGT AAT.ATT AG.CT AG.CT AG.CT AAAC.GTTT AT.AT AAAAAT.ATTTTT AC.GT AC.GT AC.GT ACCT.AGGT AAAAG.CTTTT AT.AT AAAC.GTTT AT.AT AAAAT.ATTTT AAAC.GTTT AC.GT AAAT.ATTT AG.CT AT.AT AATT.AATT AC.GT AAAT.ATTT AAT.ATT AT.AT AAC.GTT AAAAC.GTTTT

1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

29519836 29698715 29745805 29812304 30174340 30200631 30447306 30811903 30811903 30900483 31006824 31039621 31105306 31191487 31295451 31461209 31466850 31617834 31631155 31803525 31826720 31939315 31964740 32037086 32360390 32402539 32483080 32554196 32870857 32938888 32972569 33044810 33103392 33238752 33355327 33448520 33663032 33690056 33975908 34001299 34169566 34244945 34361506 34703924 34917240 35014407 35037599 35604637 35707441 35781903 36220332 36257153 36387088 36418105 36499250 36577899 36779877 36914123 36951166 36972239 36998013 37114618 37126147 37469021 37501715 37979270 38408590 38665448 38668295 38694394 38731088 38790209 38790423 39040859 39292573 39425336 39625199 39838847 39847813 39872694 39873337 40017272 40201536 40218686

29519854 29698731 29745818 29812316 30174354 30200649 30447320 30811919 30811919 30900497 31006839 31039637 31105316 31191507 31295462 31461221 31466862 31617851 31631167 31803551 31826734 31939329 31964755 32037097 32360412 32402555 32483096 32554222 32870866 32938907 32972579 33044822 33103420 33238762 33355337 33448531 33663074 33690076 33975918 34001311 34169580 34244968 34361523 34703943 34917259 35014428 35037612 35604648 35707460 35781938 36220344 36257185 36387100 36418122 36499264 36577927 36779900 36914133 36951175 36972248 36998048 37114644 37126168 37469044 37501725 37979294 38408616 38665488 38668306 38694430 38731102 38790238 38790444 39040885 39292588 39425353 39625213 39838872 39847843 39872717 39873368 40017297 40201555 40218710

4.75 5.66667 7 6.5 7.5 9.5 7.5 5.66667 5.66667 5 4 5.66667 5.5 5.25 6 6.5 6.5 3.6 6.5 6.75 3.75 7.5 8 6 5.75 4.25 8.5 6.75 5 10 5.5 6.5 9.66667 5.5 5.5 6 8.6 4.2 5.5 6.5 5 8 4.5 3.33333 4 11 7 6 4 18 6.5 16.5 6.5 4.5 3.75 4.83333 8 5.5 5 5 9 13.5 3.66667 12 5.5 12.5 6.75 8.2 6 9.25 7.5 6 5.5 13.5 4 9 7.5 6.5 15.5 6 10.6667 13 6.66667 5

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000025418 . intron ENSSSCT00000034480 MAP3K5 intron ENSSSCT00000025418 . intron ENSSSCT00000025418 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000004608 HBS1L intron ENSSSCT00000029261 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000004611 SLC2A12 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000004629 STX7 promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000004646 . intron ENSSSCT00000004646 . intron ENSSSCT00000004648 . intron ENSSSCT00000004648 . intron . . intergenic ENSSSCT00000004650 PTPRK intron ENSSSCT00000004650 PTPRK intron ENSSSCT00000004650 PTPRK intron ENSSSCT00000004650 PTPRK intron ENSSSCT00000004650 PTPRK intron ENSSSCT00000004650 PTPRK intron ENSSSCT00000004650 PTPRK intron . . intergenic . . intergenic ENSSSCT00000004657 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

. -0.136 -0.162 -0.048 -0.036 -0.103 . 0.346 0.346 . 0.311 0.264 -0.162 0.033 . 0.318 0.004 0.172 0.096 0.468 0.184 0.184 0.095 0.065 0.16 0.307 0.1 -0.018 0.022 0.109 . . 0.129 . 0.165 0.082 0.122 0.193 0.025 -0.218 0.747 . 0.028 . 0.136 0.098 -0.124 . -0.028 0.204 0.205 0.04 . 0.432 -0.137 0.06 . -0.196 -0.134 0.419 . -0.136 0.187 0.054 0.093 . 0.519 0.057 . 0.038 -0.038 4.065 3.643 0.018 . 0.027 0.16 -0.046 0.16 0.095 0.127 0.172 0.128 .

. . rs791800352 rs786479551 . rs792468410 503564 rs7927 rs789892211 rs789892211 378393 rs7932 rs789938523 rs791577097 585323 rs7882 rs786286157 rs695309575 rs792518567 rs691964012 rs791663684 . 794696 rs7910 rs792727813 rs793539951 469178 rs7872 rs791285537 . rs792721706 . rs788908377 rs789465370 rs793587743 rs789858920 rs789977224 rs696764037 955231 rs7924 900187 rs7894 566407 rs6963 rs692570749 180519 rs7879 rs787694904 rs702970519 rs792874633 rs791734867 . rs786759960 rs791576210 . rs790592337 rs788086882 rs790491269 . 780242 rs7893 rs791413266 096972 rs7933 rs792313104 rs792523257 rs789959299 rs790741775 . . 388982 rs7881 rs790793036 . 716399 rs7911 rs789237962 rs789994649 rs790658527 rs793397346 rs698167926 rs789406737 rs793156035 rs789238536 rs792994735 . rs787402741 403547 rs7880 894044 rs7869 rs786232848 rs793138401 rs790933277 rs792178259 rs789883712 427596 rs7938 rs786287949 rs792066293

2 3 2 2 3 3 2 2 2 2 2 2 2 2 2 3 2 3 3 3 2 2 2 3 2 2 3 2 2 2 2 2 2 3 3 3 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 4 2 2 2 2 2 2 2 3 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 3 2 2 2 2 2

AAAAC.GTTTT AC.GT AC.GT ACTCT.AGAGT AAAC.GTTT AC.GT AC.GT AAC.GTT AAAAT.ATTTT AAAC.GTTT ACGC.GCGT AT.AT AAT.ATT AG.CT AAAC.GTTT AC.GT AAT.ATT AC.GT AC.GT AAAT.ATTT AAAAG.CTTTT AC.GT AAC.GTT AAT.ATT AAT.ATT AAT.ATT AAAC.GTTT AAAC.GTTT AG.CT AC.GT AAAT.ATTT AAAC.GTTT AT.AT AAC.GTT AAAC.GTTT AATT.AATT AG.CT AAAT.ATTT AAAC.GTTT AT.AT AAAT.ATTT AG.CT AAC.GTT AT.AT AAC.GTT AC.GT AAAT.ATTT AAAC.GTTT AAC.GTT AAAAC.GTTTT AG.CT AT.AT AAAC.GTTT AAAC.GTTT AAG.CTT AATG.CATT AAAAC.GTTTT AAAAC.GTTTT AC.GT AT.AT AATAC.GTATT AT.AT AAAG.CTTT AAAAC.GTTTT AAC.GTT AT.AT AG.CT AG.CT AAT.ATT AAAC.GTTT AT.AT AT.AT AAC.GTT AT.AT AAC.GTT AAAT.ATTT AAAC.GTTT AT.AT AC.GT AT.AT AAAAT.ATTTT AAAC.GTTT AC.GT AAAC.GTTT

1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

40581538 40607227 40934783 41026982 41479169 42040798 42327669 42448247 42714130 42874049 42938175 42958453 43186991 43275152 43297277 43466116 43502935 43566732 43616051 43697562 43932329 43937111 43974992 44089536 44089536 44089536 44159818 44171450 44736625 45030265 45163763 45175722 45222384 45252182 45333005 45433128 45499676 45739199 45784509 45792245 45807102 45981913 45990524 46224422 46480135 47167554 47340700 47406087 47496552 47984615 48202205 48281554 48333168 48592701 48819457 48984816 49028360 49257643 49312173 49540762 49565727 49591149 49594084 49723035 49781713 49814565 49816006 49821229 49881944 50031303 50090476 50112443 50965905 51030264 51415020 51490970 51535089 51568236 51820026 51998574 52085844 52148276 52149954 52418691

40581566 40607241 40934801 41026996 41479192 42040807 42327679 42448260 42714146 42874063 42938193 42958462 43187014 43275161 43297303 43466134 43502948 43566744 43616071 43697579 43932353 43937124 43975005 44089552 44089552 44089552 44159848 44171472 44736654 45030278 45163786 45175740 45222406 45252196 45333018 45433149 45499688 45739213 45784555 45792260 45807128 45981925 45990539 46224432 46480157 47167565 47340716 47406113 47496570 47984632 48202235 48281564 48333186 48592720 48819473 48984847 49028377 49257666 49312188 49540776 49565755 49591158 49594097 49723052 49781736 49814591 49816016 49821241 49881973 50031325 50090496 50112457 50965928 51030275 51415035 51490987 51535103 51568249 51820040 51998585 52085865 52148290 52149972 52418717

5.8 7.5 9.5 3 6 5 5.5 4.66667 3.4 3.75 4.75 5 8 5 6.75 9.5 4.66667 6.5 10.5 4.5 5 7 4.66667 5.66667 5.66667 5.66667 7.75 5.75 15 7 6 4.75 11.5 5 3.5 5.5 6.5 3.75 11.75 8 6.75 6.5 5.33333 5.5 7.66667 6 4.25 6.75 6.33333 3.6 15.5 5.5 4.75 5 5.66667 8 3.6 4.8 8 7.5 5.8 5 3.5 3.6 8 13.5 5.5 6.5 10 5.75 10.5 7.5 8 6 5.33333 4.5 3.75 7 7.5 6 4.4 3.75 9.5 6.75

. . ENSSSCT00000027938 . . . . . . . . . . . . . ENSSSCT00000029492 . . . ENSSSCT00000004677 ENSSSCT00000004677 ENSSSCT00000004677 ENSSSCT00000033012 ENSSSCT00000034434 ENSSSCT00000004678 . . . . . . . . . . . ENSSSCT00000004689 ENSSSCT00000004689 ENSSSCT00000004689 ENSSSCT00000004689 . . . . . . . . ENSSSCT00000004691 ENSSSCT00000004692 . ENSSSCT00000004693 . . ENSSSCT00000004697 ENSSSCT00000004697 . . . ENSSSCT00000004699 ENSSSCT00000004701 ENSSSCT00000004701 . ENSSSCT00000029401 ENSSSCT00000029401 ENSSSCT00000029401 ENSSSCT00000029401 ENSSSCT00000004703 . . . . . . . . . . . . . . .

. . NCOA7 . . . . . . . . . . . . . TRDN . . . CLVS2 CLVS2 CLVS2 SMPDL3A SMPDL3A SMPDL3A . . . . . . . . . . . TBC1D32 TBC1D32 TBC1D32 TBC1D32 . . . . . . . . MAN1A1 FAM184A . MCM9 . . SLC35F1 SLC35F1 . . . . GOPC GOPC . ROS1 ROS1 ROS1 ROS1 VGLL2 . . . . . . . . . . . . . . .

intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intron intergenic intergenic intron intron intergenic intergenic intergenic intron intron intron intergenic intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

-0.154 -0.028 -0.106 0.193 -0.083 0.247 -0.124 0.71 0.105 -0.005 -0.18 -0.179 -0.08 0.275 0.192 0.531 -0.221 -0.131 -0.144 . -0.009 0.044 0.139 -0.154 -0.154 -0.154 . 0.08 -0.029 -0.049 -0.062 0.125 0.009 0.138 0.03 -0.015 1.35 . 0.099 . . 0.369 0.068 0.03 . 0.055 -0.033 -0.127 0.08 0.031 0.123 . 0.134 0.285 0.182 -0.049 -0.14 0.267 0.763 . 0.192 0.027 . . 1.769 0.236 -0.052 0.072 0.237 0.393 0.009 . 0.115 -0.286 -0.112 . -0.25 0.066 . . -0.016 -0.063 -0.078 0.499

rs791198671 rs792296636 rs791588396 rs789251351 rs789018301 rs793294116 rs792718851 rs791578037 rs792758029 rs789692543 rs792144167 rs790256328 . rs793015065 rs791827495 183380 rs7876 . rs790494770 rs787543403 rs791628028 167133 rs7894 . rs791614704 rs788892991 rs788892991 rs788892991 rs789277234 rs786973217 622824 rs7867 rs793291164 071294 rs7906 rs788602046 rs788705357 rs786255226 rs787514789 rs789200495 . rs788758978 rs788627854 rs788964391 rs792553793 . 230982 rs7875 rs791374551 rs792875546 . 531314 rs7915 667789 rs7884 850954 rs7938 . 125083 rs7919 rs793280148 259831 rs7932 rs787781254 471355 rs7934 rs793239753 rs793206570 rs789687289 800714 rs7929 rs792540454 rs786871772 rs791762296 rs788965010 731484 rs7863 rs793825776 299273 rs7930 rs791713439 792624 rs7867 270292 rs7912 rs792271105 rs789890725 rs792997640 418470 rs7937 . rs787793039 rs790714614 rs787218245 626012 rs7891 rs787905262 rs789870168 278586 rs7906 rs788204617 . rs788152693

2 3 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 3 2 4 2 2 2 2 3 2 2 2 2 2 2 4 2 2 2 2 2 2 3 2 2 2 2 2 3 2 2 2 2 2 2 3 2 2 4 2

AG.CT AAAC.GTTT AT.AT AC.GT AG.CT AAAT.ATTT AAAT.ATTT AAT.ATT AAAT.ATTT AG.CT AAGG.CCTT AAC.GTT AT.AT AT.AT AAAAC.GTTTT AC.GT AAAC.GTTT AAAT.ATTT AG.CT AT.AT AT.AT AT.AT AAAC.GTTT AT.AT AAAAC.GTTTT AAC.GTT AT.AT AAAC.GTTT AAAAAC.GTTTTT AG.CT AAAAC.GTTTT AT.AT AAATAG.CTATTT AT.AT AAAC.GTTT ACAT.ATGT AAAAT.ATTTT AC.GT AAT.ATT ATC.GAT AG.CT AAAC.GTTT AT.AT AAAAG.CTTTT AG.CT AG.CT AC.GT AG.CT AAAC.GTTT AAAG.CTTT ACC.GGT AAAAC.GTTTT AAT.ATT AAAG.CTTT AAAAC.GTTTT AT.AT AT.AT AAC.GTT AC.GT AC.GT AT.AT AAT.ATT ATCC.GGAT AAAAT.ATTTT AAT.ATT AAAT.ATTT AAAC.GTTT AC.GT AG.CT AT.AT AAAG.CTTT AAAT.ATTT AAAT.ATTT AAAC.GTTT AATT.AATT AAAC.GTTT AT.AT AAAAT.ATTTT AG.CT AAAAC.GTTTT AC.GT AAG.CTT AC.GT AAAAC.GTTTT

1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

52433160 52521132 52602233 52609675 52809987 52961824 52981958 53063505 53152663 53411464 53665506 54007386 54125420 54756818 54766526 54829662 54853395 55042066 55068231 55088385 55292363 55388423 55419931 55557246 55674261 55842785 55949280 55978380 56065330 56322836 56766781 56835837 57020516 57284988 57345496 57388624 57394415 57576736 57619904 57823485 57857687 57899650 57901826 57939720 58141913 58320254 58404370 58566974 58636080 58671786 58866687 59037392 59051657 59092158 59328526 59366349 59366349 59551967 59739540 60039276 60214391 60558740 60751412 60889906 60905397 61006591 61539589 61556464 62012587 62024381 62062816 62379993 62407926 62436537 62440067 62790015 62817841 62900592 63071982 63307658 63374393 63383771 63447148 63473963

52433172 52521150 52602244 52609687 52810009 52961844 52982001 53063531 53152679 53411473 53665521 54007401 54125431 54756829 54766545 54829675 54853407 55042088 55068243 55088394 55292372 55388435 55419949 55557257 55674289 55842797 55949296 55978406 56065352 56322859 56766802 56835846 57020535 57284997 57345518 57388644 57394430 57576746 57619922 57823505 57857705 57899673 57901844 57939741 58141928 58320265 58404380 58566993 58636096 58671805 58866703 59037421 59051668 59092176 59328541 59366359 59366359 59551979 59739552 60039302 60214403 60558758 60751439 60889930 60905414 61006617 61539611 61556478 62012603 62024395 62062831 62380006 62407947 62436556 62440089 62790030 62817866 62900606 63071992 63307681 63374402 63383782 63447162 63473986

6.5 4.75 6 6.5 11.5 5.25 11 9 4.25 5 4 5.33333 6 6 4 7 3.25 5.75 6.5 5 5 6.5 4.75 6 5.8 4.33333 8.5 6.75 3.83333 12 4.4 5 3.33333 5 5.75 5.25 3.2 5.5 6.33333 7 9.5 6 9.5 4.4 8 6 5.5 10 4.25 5 5.66667 6 4 4.75 3.2 5.5 5.5 4.33333 6.5 13.5 6.5 6.33333 7 5 6 6.75 5.75 7.5 8.5 7.5 4 3.5 5.5 5 5.75 4 13 3 5.5 4.8 5 4 7.5 4.8

. . . . . . . . . . . . . . . . . . . . . ENSSSCT00000004719 ENSSSCT00000004719 ENSSSCT00000004719 ENSSSCT00000004719 . . . ENSSSCT00000004721 ENSSSCT00000004722 ENSSSCT00000004723 . . ENSSSCT00000024170 ENSSSCT00000024170 . . . . . . . . . . . ENSSSCT00000004730 ENSSSCT00000004730 . . . . . . . ENSSSCT00000004740 ENSSSCT00000023321 . ENSSSCT00000004742 . ENSSSCT00000004744 . . . ENSSSCT00000004747 ENSSSCT00000004748 . . . . . ENSSSCT00000029112 . . . ENSSSCT00000004762 . . . . . . . .

. . . . . . . . . . . . . . . . . . . . . BAI3 BAI3 BAI3 BAI3 . . . LMBRD1 COL19A1 COL9A1 . . B3GAT2 B3GAT2 . . . . . . . . . . . RIMS1 RIMS1 . . . . . . . DDX43 CYB5R4 . KIAA1009 . TBX18 . . . SNX14 SYNCRIP . . . . . ZNF292 . . . AKIRIN2 . . . . . . . .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intron intron intron intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intron intergenic intron intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic 3'utr intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

0.241 0.037 -0.011 0.272 . . -0.151 . . . -0.053 . -0.046 0.213 . . . . 0.284 -0.109 0.05 0.021 . . -0.037 . 0.08 0.11 0.066 0.017 0.301 0.153 0.086 . . . . 0.214 . -0.005 -0.077 . -0.019 0.641 0.261 0.032 0.053 -0.3 0.023 0.157 0.023 . 0.088 . . -0.184 -0.184 . 0.109 0.201 0.38 0.097 -0.076 0.178 1.934 4.12 0.1 0.124 0.563 . 0.035 0.293 -0.049 0.166 0.159 . 0.2 0.027 0.009 0.216 -0.222 0.398 0.32 0.182

rs792664890 rs786645131 . rs787436227 rs792994759 . rs786384731 rs792150368 rs791317766 . rs693352739 rs791944749 080604 rs7871 rs790436411 892297 rs7901 . rs787786107 rs786786479 . rs788165428 rs789434919 rs788590703 rs789873526 093585 rs7936 rs788855722 rs793884080 rs787560591 rs790761851 rs790238799 rs790666988 rs786217443 . rs786972921 . rs791689238 rs789294864 rs789500911 rs793791655 rs789518475 rs787917129 431688 rs7934 rs786533512 . rs704974494 rs787229297 997603 rs7862 rs792964788 rs790102141 rs787043340 828174 rs7938 rs791299335 rs788144130 rs791788582 rs792035886 rs788688388 rs789954417 rs789954417 . rs786526874 rs787927710 . . 198232 rs7877 rs792451913 372845 rs7929 093812 rs7932 rs789077953 rs791191714 rs792872172 . . rs786818103 rs786672980 146663 rs7917 rs793147507 573312 rs7928 . rs792325963 . rs789573594 rs788338558 059288 rs7888 rs793252978 rs788417584

4 2 3 4 2 2 2 2 2 3 2 2 2 2 2 3 3 2 3 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 4 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 3 3 2 2 2 2 2 2 2 2 3 2 2 4 2 2

AAAAC.GTTTT AC.GT AT.AT AT.AT AAC.GTT AAAAC.GTTTT AAAAC.GTTTT AATG.CATT AAAG.CTTT AG.CT AC.GT AT.AT AC.GT AT.AT AT.AT AC.GT AC.GT AAAT.ATTT AT.AT AAAAG.CTTTT AAG.CTT AT.AT AAT.ATT AAAC.GTTT AT.AT AC.GT ATC.GAT AG.CT AG.CT AC.GT AG.CT AT.AT AC.GT AC.GT AT.AT AAT.ATT AG.CT ACAT.ATGT AT.AT AT.AT AT.AT AAG.CTT ACAG.CTGT AC.GT AAAC.GTTT AC.GT AT.AT AT.AT AT.AT AAAAAC.GTTTTT AAAC.GTTT AAT.ATT AAAAAT.ATTTTT AAAT.ATTT AG.CT AAAT.ATTT AG.CT AC.GT AT.AT AAAAC.GTTTT AGG.CCT AG.CT AC.GT AG.CT AAC.GTT AT.AT AG.CT AAAC.GTTT AAAC.GTTT AC.GT AAAT.ATTT AACT.AGTT AAAC.GTTT AAAC.GTTT AAAG.CTTT AAAG.CTTT AT.AT AT.AT AAAAC.GTTTT AAAAC.GTTTT AAAT.ATTT AAAT.ATTT AAT.ATT AAT.ATT

1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

63673626 64362444 64741617 64741617 64979479 65192289 65224399 65311927 65367475 65763250 66048304 66123484 66224158 66265022 66445628 66457452 66744550 67058682 67244439 67359354 67549563 68132123 68874901 68886557 69105307 69598605 69610242 69642707 69807950 70032511 70144263 70192148 70374929 70908997 71100499 71129560 71138631 71193879 71430084 71452036 71629379 71851218 71947359 71994527 72272987 72380406 72408881 72408881 72883454 72917693 73691003 73849452 73874251 73895895 73952002 74214254 74215940 74274815 74330827 74453887 74926707 74942943 75177547 75460762 75634314 76097926 76106519 76555888 76749396 76947261 76973342 77101986 77186796 77186796 77200534 77200534 77206723 77206723 77223155 77223155 77345200 77345200 77517036 77517036

63673642 64362456 64741628 64741628 64979491 65192304 65224422 65311947 65367518 65763259 66048320 66123494 66224190 66265035 66445644 66457466 66744591 67058696 67244450 67359369 67549576 68132147 68874912 68886575 69105325 69598618 69610264 69642732 69807961 70032524 70144297 70192160 70374948 70909008 71100512 71129577 71138645 71193899 71430093 71452046 71629389 71851249 71947377 71994541 72273000 72380416 72408894 72408894 72883471 72917715 73691038 73849471 73874272 73895909 73952013 74214267 74215956 74274825 74330836 74453901 74926721 74942957 75177565 75460779 75634333 76097938 76106530 76555909 76749415 76947281 76973362 77101999 77186822 77186822 77200561 77200561 77206749 77206749 77223178 77223178 77345220 77345220 77517062 77517062

3.4 6.5 6 6 4.33333 3.2 4.8 5.25 11 5 8.5 5.5 16.5 7 8.5 7.5 21 3.75 6 3.2 4.66667 12.5 4 4.75 9.5 7 7.66667 13 6 7 17.5 6.5 10 6 7 6 7.5 5.25 5 5.5 5.5 10.6667 4.75 7.5 3.5 5.5 7 7 9 3.83333 9 6.66667 3.66667 3.75 6 3.5 8.5 5.5 5 3 5 7.5 9.5 9 6.66667 6.5 6 5.5 5 10.5 5.25 3.5 6.75 6.75 7 7 13.5 13.5 4.8 4.8 5.25 5.25 9 9

ENSSSCT00000029164 . intron . . intergenic ENSSSCT00000027915 . intron ENSSSCT00000004785 . intron ENSSSCT00000004788 BACH2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000029077 NDUFAF4 intron ENSSSCT00000004798 NDUFAF4 intron ENSSSCT00000004802 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000004804 FBXL4 intron . . intergenic ENSSSCT00000004805 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000032833 GRIK2 intron ENSSSCT00000004819 GRIK2 intron ENSSSCT00000032833 GRIK2 intron ENSSSCT00000004819 GRIK2 intron ENSSSCT00000032833 GRIK2 intron ENSSSCT00000004819 GRIK2 intron ENSSSCT00000032833 GRIK2 intron ENSSSCT00000004819 GRIK2 intron ENSSSCT00000032833 GRIK2 intron ENSSSCT00000004819 GRIK2 intron ENSSSCT00000035045 GRIK2 intron ENSSSCT00000004819 GRIK2 intron

. 0.275 . . 0.305 -0.089 -0.044 0.031 0.314 . 0.164 0.151 0.034 0.025 0.119 0.537 -0.15 . -0.061 -0.025 . -0.081 0.032 . -0.021 -0.018 -0.151 0.006 . -0.03 0.039 . -0.024 0.101 0.095 0.256 . . 0.121 -0.084 0.142 0.109 0.398 0.083 0.148 0.551 0.083 0.083 . . 0.054 0.086 -0.179 0.032 0.137 -0.001 0.314 0.21 0.114 0.149 0.07 0.08 . 0.176 . 0.151 -0.022 . . 0.368 -0.019 . -0.086 -0.086 1.065 1.065 0.075 0.075 . . 0.422 0.422 -0.036 -0.036

rs789276901 rs789515298 rs793485844 rs793485844 rs786290649 rs791835771 rs792420111 rs793870556 rs790552560 rs793044469 001117 rs7915 rs790986049 rs793249009 rs793733624 rs788273912 898088 rs7930 605125 rs7884 rs790428743 . rs791119865 rs789044493 rs712254206 rs786663249 142729 rs7871 rs790754580 rs692181455 . rs791158789 . rs787530510 rs789190993 rs793278755 844603 rs7872 rs791088007 rs791520505 rs791957658 rs786552360 964225 rs7936 rs789459557 rs789796795 . rs789240231 rs790216507 . 842770 rs7884 rs788473725 rs787641866 rs787641866 . rs790450543 rs793281321 . 406965 rs7883 . rs787510403 rs790450786 rs789160924 rs789534369 . . . rs791406515 rs789045638 rs702096286 797363 rs7903 rs790737973 rs788078783 rs790972507 rs789418874 033003 rs7898 . rs789726133 208126 rs7865 208126 rs7865 271576 rs7891 271576 rs7891 . . rs786385099 rs786385099 rs790811796 rs790811796 rs787870500 rs787870500

2 2 3 3 2 2 2 2 2 2 4 2 4 2 2 2 2 3 2 2 2 2 2 3 2 3 3 4 4 2 2 2 3 4 2 2 2 2 2 2 4 2 2 3 2 2 2 2 3 2 2 2 2 2 2 2 3 2 3 2 2 2 6 3 2 3 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2

AC.GT AT.AT AG.CT AG.CT AG.CT AG.CT AAAAT.ATTTT AAAAAC.GTTTTT AC.GT AT.AT AT.AT AG.CT AG.CT AC.GT AAAAAT.ATTTTT AC.GT AG.CT AAAT.ATTT AAAAAT.ATTTTT AAAAG.CTTTT AC.GT AAAC.GTTT AAAC.GTTT AAAT.ATTT AAAT.ATTT AAC.GTT AT.AT AAAG.CTTT AAAAAT.ATTTTT AC.GT AAAC.GTTT AATG.CATT AAG.CTT AG.CT AT.AT AC.GT AAAT.ATTT AAC.GTT AC.GT AC.GT AT.AT AT.AT AAAC.GTTT AG.CT AAAAAC.GTTTTT AT.AT AAAAC.GTTTT AAAAT.ATTTT AATG.CATT AC.GT AAAG.CTTT AT.AT AT.AT AAAC.GTTT AC.GT AG.CT AAAC.GTTT AGG.CCT AAAAC.GTTTT AAAC.GTTT AT.AT AAC.GTT AAC.GTT AAC.GTT AC.GT AAAAC.GTTTT AAG.CTT AC.GT AAAAGC.GCTTTT AAAAGC.GCTTTT AAAAGC.GCTTTT AGAT.ATCT AGAT.ATCT AGAT.ATCT AAAG.CTTT AG.CT AAAAC.GTTTT AAC.GTT AT.AT AC.GT AT.AT AAT.ATT AAAG.CTTT AG.CT

1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

77967026 78067448 78073332 78363036 78376790 78434834 78444928 78559613 78621379 78871183 78956582 79026382 79096147 79452380 79556831 79568793 79622915 79919873 79975403 80213002 80294279 80409159 80425859 80665016 80665016 80745434 80893253 81155518 81286437 81386354 81388698 81883838 82131564 82169733 82306148 82428557 82652788 82665154 82719863 82845362 83007068 83210423 83523580 83618869 83721148 83852158 83989803 84027916 84175909 84176691 84405669 84512121 84512121 84655744 84671844 84802871 84877908 85162623 85186920 85199328 86000503 86046218 86076678 86320573 86353179 86921610 87126065 87140027 87249168 87249168 87249168 87377759 87377759 87377759 87519823 87648187 87735253 87735353 87759643 88470564 88605136 88903340 89168891 89171593

77967036 78067458 78073345 78363061 78376818 78434848 78444942 78559638 78621389 78871197 78956608 79026400 79096157 79452390 79556856 79568804 79622926 79919895 79975430 80213035 80294300 80409172 80425888 80665036 80665036 80745448 80893263 81155539 81286473 81386364 81388720 81883857 82131581 82169744 82306162 82428571 82652806 82665173 82719876 82845373 83007078 83210433 83523601 83618893 83721169 83852168 83989840 84027937 84175936 84176703 84405699 84512130 84512130 84655758 84671856 84802881 84877934 85162635 85186936 85199371 86000512 86046229 86076700 86320596 86353193 86921633 87126082 87140039 87249191 87249191 87249191 87377786 87377786 87377786 87519835 87648198 87735275 87735367 87759665 88470587 88605147 88903355 89168922 89171613

5.5 5.5 7 13 14.5 7.5 3 4.33333 5.5 7.5 13.5 9.5 5.5 5.5 4.33333 6 6 5.75 4.66667 6.8 11 3.5 7.5 5.25 5.25 5 5.5 5.5 6.16667 5.5 5.75 5 6 6 7.5 7.5 4.75 6.66667 7 6 5.5 5.5 5.5 12.5 3.66667 5.5 7.6 4.4 7 6.5 7.75 5 5 3.75 6.5 5.5 6.75 4.33333 3.4 11 5 4 7.66667 8 7.5 4.8 6 6.5 4 4 4 7 7 7 3.25 6 4.6 5 11.5 12 6 5.33333 8 10.5

. . . . . . . . . . . . . . . . . . . . ENSSSCT00000004823 . . ENSSSCT00000004826 ENSSSCT00000004825 . ENSSSCT00000004829 . . . . . ENSSSCT00000004835 . . . . . . . . . . . ENSSSCT00000004848 . ENSSSCT00000004849 ENSSSCT00000004849 . . . ENSSSCT00000004854 ENSSSCT00000029999 ENSSSCT00000004878 ENSSSCT00000004878 . ENSSSCT00000004874 . . . . ENSSSCT00000004862 . ENSSSCT00000004857 ENSSSCT00000004856 ENSSSCT00000025331 . . ENSSSCT00000004886 ENSSSCT00000004884 ENSSSCT00000004885 ENSSSCT00000004886 ENSSSCT00000004884 ENSSSCT00000004885 . . . . ENSSSCT00000004890 . . . . .

. . . . . . . . . . . . . . . . . . . . HACE1 . . BVES BVES . PREP . . . . . . . . . . . . . . . . . . . FOXO3A FOXO3A . . . CEP57L1 CEP57L1 . . . ZBTB24 . . . . SLC22A16 . RPF2 GTF3C6 . . . FYN FYN FYN FYN FYN FYN . . . . . . . . . .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intron intron intergenic promoter intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intron intron intergenic intergenic intergenic intron intron intron intron intergenic promoter intergenic intergenic intergenic intergenic intron intergenic intron 3'utr intron intergenic intergenic intron intron intron intron intron intron intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic

. 0.169 0.019 -0.084 0.461 0.511 0.229 0.287 0.4 -0.019 . . . 0.098 0.232 . . 0.003 1.101 0.19 0.373 0.266 0.247 0.266 0.266 . 0.109 0.073 . 0.271 -0.28 0.049 0.376 . . -0.148 0.211 0.081 . 0.784 . 0.02 0.248 0.198 . . 0.107 . -0.023 . 0.292 . . . -0.052 0.196 . 0.359 0.146 0.312 . 0.2 -0.002 -0.167 0.075 0.324 0.245 1.152 1.697 1.697 1.697 . . . -0.045 . . . . 0.55 -0.021 0.063 -0.009 0.197

rs787761492 rs790838868 rs789803196 rs790316557 rs786837778 . . 315042 rs7870 . rs789040157 rs793506424 . . . rs788252706 rs791259860 . rs788944966 rs792619341 800033 rs7900 rs793069219 604889 rs7866 rs786527673 rs789174196 rs789174196 . . . rs787782609 rs791121836 rs789920509 rs787241279 rs786761030 rs792644708 130261 rs7866 rs791114306 . . rs791464634 rs792805843 rs788674184 088642 rs7887 968876 rs7886 rs788534522 rs790787126 rs790709432 . rs789098840 rs793573133 . . . . rs793515583 rs790155291 . rs789530094 rs792037026 rs789988478 rs789903018 rs788967357 rs787798329 001817 rs7890 rs793814625 rs788608643 rs790923989 169834 rs7868 rs694281725 rs789466128 rs789466128 rs789466128 rs791976396 rs791976396 rs791976396 . rs694852576 . 016768 rs7909 rs787062072 rs793871696 rs790173143 rs789223752 . rs788834601

2 4 2 2 2 4 2 2 2 2 2 4 4 2 2 3 4 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 4 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 3 2 2 2 2 2 2 2 2

AAAC.GTTT AAAT.ATTT AAAG.CTTT AT.AT AC.GT AAAC.GTTT AAAG.CTTT AAAT.ATTT AT.AT AAAC.GTTT AAAAT.ATTTT AT.AT AAAAC.GTTTT AT.AT AAT.ATT AAAT.ATTT AC.GT AAGG.CCTT AAAT.ATTT AAAT.ATTT AG.CT AG.CT AAAT.ATTT AAAG.CTTT AAAAC.GTTTT AG.CT AT.AT AG.CT AAC.GTT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AT.AT AAAC.GTTT AC.GT AT.AT AAAC.GTTT AG.CT AAAT.ATTT AAAT.ATTT AAAC.GTTT AAAT.ATTT AATG.CATT AC.GT AC.GT AAAT.ATTT AG.CT AT.AT AC.GT AT.AT AAC.GTT AT.AT AAAC.GTTT AAG.CTT AAT.ATT AC.GT AAAC.GTTT AG.CT AAAC.GTTT AAAAC.GTTTT AT.AT AT.AT AAAAC.GTTTT AAAC.GTTT AC.GT AATG.CATT AG.CT AAC.GTT AC.GT ACACCC.GGGTG AAAC.GTTT AGG.CCT AAT.ATT AAAC.GTTT AG.CT AG.CT AAAC.GTTT AGAT.ATCT AAC.GTT AG.CT AT.AT AC.GT AC.GT

1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

89413203 89745706 89930963 90128062 90292671 90480271 90648749 90737138 90752481 90903351 90942753 90960110 91101568 91118153 91190574 91452983 91703290 91851864 91860756 91860756 91992465 91992465 92228771 92267185 92519700 92842886 93040784 93044288 93176165 93224461 93287068 93287068 93287068 93460078 93508292 94094725 94126276 94369344 94455768 94539328 94539328 94614765 94694546 94709038 94952399 95164223 95379225 95562729 95583481 95631515 95790417 95892966 96056338 96317126 96332481 96494262 97129394 97184041 97192209 97336648 97546417 97829824 97865297 97868685 98545862 98630326 98631106 98789885 98822636 98980696 99156830 99422196 99440523 99509313 99888903 99977410 100041632 100253088 100277892 100311826 100362367 100413357 100520500 100524315

89413220 89745723 89930976 90128081 90292681 90480298 90648763 90737156 90752492 90903364 90942771 90960123 91101593 91118164 91190595 91452996 91703308 91851878 91860778 91860778 91992475 91992475 92228801 92267218 92519727 92842897 93040795 93044305 93176179 93224499 93287086 93287086 93287086 93460101 93508314 94094738 94126286 94369363 94455780 94539357 94539357 94614787 94694573 94709055 94952429 95164237 95379244 95562748 95583493 95631530 95790446 95892981 96056349 96317154 96332494 96494293 97129412 97184060 97192225 97336675 97546444 97829865 97865308 97868709 98545880 98630345 98631136 98789895 98822657 98980706 99156854 99422222 99440537 99509327 99888929 99977430 100041646 100253106 100277903 100311839 100362376 100413371 100520512 100524333

4.5 4.5 3.5 10 5.5 7 3.75 4.75 6 3.5 3.8 7 5.2 6 7.33333 3.5 9.5 3.75 5.75 5.75 5.5 5.5 7.75 8.5 5.6 6 6 9 5 7.8 4.75 4.75 4.75 12 5.75 7 5.5 5 6.5 7.5 7.5 5.75 7 4.5 15.5 7.5 5 10 6.5 8 15 5.33333 6 7.25 4.66667 10.6667 9.5 5 8.5 7 5.6 21 6 5 4.75 10 7.75 5.5 7.33333 5.5 4.16667 6.75 5 5 6.75 10.5 7.5 4.75 3 4.66667 5 7.5 6.5 9.5

. . intergenic . . intergenic ENSSSCT00000004897 HDAC2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000004900 NT5DC1 promoter ENSSSCT00000035653 NT5DC1 promoter ENSSSCT00000035653 NT5DC1 intron ENSSSCT00000004900 NT5DC1 intron . . intergenic ENSSSCT00000004906 DSE intron . . intergenic ENSSSCT00000004918 SNAP91 intron . . intergenic . . intergenic ENSSSCT00000004920 ME1 intron ENSSSCT00000004920 ME1 intron ENSSSCT00000035912 DOPEY1 intron ENSSSCT00000004923 DOPEY1 intron ENSSSCT00000022952 DOPEY1 intron ENSSSCT00000032416 . intron ENSSSCT00000025129 UBE3D intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000004926 IBTK intron ENSSSCT00000021698 SNORD112 promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000024946 BCKDHB intron . . intergenic . . intergenic . . intergenic ENSSSCT00000004936 LCA5 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

0.698 . . 0.105 0.343 . 0.039 -0.271 -0.073 -0.127 0.088 -0.253 0.579 0.002 -0.035 0.16 -0.015 0.115 0.084 0.084 0.187 0.187 0.355 . . -0.047 0.513 . . 0.058 0.238 0.238 0.238 0.39 0.083 0.09 . 0.177 0.381 -0.095 -0.095 . . 0.104 0.252 0.222 0.136 . -0.317 -0.083 . -0.002 . 0.022 0.142 0.007 . -0.201 -0.053 0.14 . -0.094 0.187 0.099 . 0.079 0.06 . . . 0.002 . . 0.178 . . . 0.251 0.165 . . . 0.006 0.036

rs791435727 rs793270621 890355 rs7863 . rs790990254 rs793244422 rs791190943 rs787229695 rs788909394 . rs789057237 rs789817240 220656 rs7867 rs792534764 rs700471871 rs790173712 . rs790550013 773771 rs7867 773771 rs7867 rs792074774 rs792074774 rs708434469 rs790557641 rs792614937 rs789250221 204508 rs7907 . rs792484034 rs787861998 rs789532639 rs789532639 rs789532639 . rs787501743 rs793085506 . 918074 rs7923 rs792648033 rs793297516 rs793297516 rs786298667 rs788118469 . rs788197600 . rs793238310 rs791537104 rs791821044 rs790223518 rs789568397 rs790286441 rs788789194 048889 rs7907 rs788172496 rs790914807 rs793306491 rs787623495 486374 rs7886 rs787117732 rs789252979 rs790211222 rs792790144 rs790692992 971501 rs7914 rs792249373 711505 rs7899 . 777318 rs7935 . rs792715940 rs788734692 rs788903210 rs793795513 rs793687577 rs787679454 rs789698475 605251 rs7931 472777 rs7894 rs791186672 rs789249129 . rs786946960 rs706172646

2 2 2 4 4 2 2 2 2 3 2 2 2 2 2 2 4 3 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 3 2 4 2 3 2 2 2 3 2 2 2 2 2 2 2 2 3 2

AAAC.GTTT AAGG.CCTT AAAC.GTTT AG.CT AAAAC.GTTTT ACAT.ATGT AT.AT AAAC.GTTT AAACC.GGTTT AC.GT AC.GT AC.GT AT.AT AC.GT AC.GT AC.GT AAC.GTT AAAAT.ATTTT AC.GT AC.GT AATG.CATT AAAC.GTTT AT.AT AAAT.ATTT AAG.CTT AC.GT AC.GT AAG.CTT AT.AT AAAC.GTTT AG.CT AG.CT AAG.CTT AAT.ATT AC.GT AAAAAC.GTTTTT AATG.CATT AAGG.CCTT AG.CT AG.CT AAAAC.GTTTT AT.AT AATG.CATT ATC.GAT ACC.GGT AAAC.GTTT AAAC.GTTT AAT.ATT ATC.GAT AT.AT AAAAT.ATTTT AGGG.CCCT AAAC.GTTT AT.AT AAAC.GTTT AT.AT AAAAC.GTTTT AC.GT AAAC.GTTT AC.GT AAAAG.CTTTT AAAC.GTTT AAAT.ATTT AT.AT AC.GT AAC.GTT AAAC.GTTT AC.GT AAAAC.GTTTT AT.AT AC.GT AC.GT AAT.ATT AAAC.GTTT AAC.GTT AAAAAC.GTTTTT AC.GT AAAC.GTTT AT.AT AG.CT AAAAC.GTTTT AAGG.CCTT AT.AT AT.AT

1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

101291815 101345322 101501462 101625294 102002980 102165762 102449738 102627186 102657847 103175127 103175127 103175127 103363625 103667558 103685722 104155184 104675818 104937520 104950580 105269509 105438596 105900826 105921955 105929361 106097505 106147009 106761598 106978525 107009267 107048037 107131892 107182157 107284891 107386051 107450784 107475981 107562149 107606974 107626845 107677091 107783811 107926894 108006850 108040423 108062550 108210151 108327711 108363617 108380999 108763075 109260733 109672566 109674731 109742803 109815609 109931016 110428109 110554404 110567061 110601493 110739714 110979348 110989580 111321430 111333173 112151793 112314873 112485332 112596416 112649623 112876668 113027818 113139576 113307237 113575862 113879872 113903797 114102739 114111969 114329334 114560756 114737550 115122403 115122403

101291826 101345335 101501489 101625306 102003004 102165775 102449750 102627230 102657863 103175137 103175137 103175137 103363634 103667568 103685732 104155193 104675831 104937538 104950590 105269529 105438644 105900850 105921964 105929376 106097517 106147022 106761610 106978538 107009278 107048056 107131908 107182168 107284907 107386063 107450795 107476010 107562166 107607023 107626865 107677109 107783831 107926905 108006873 108040434 108062565 108210166 108327732 108363635 108381019 108763093 109260750 109672580 109674747 109742812 109815627 109931030 110428131 110554420 110567082 110601505 110739733 110979366 110989596 111321439 111333198 112151812 112314904 112485348 112596438 112649640 112876681 113027835 113139606 113307261 113575884 113879899 113903807 114102752 114111978 114329344 114560784 114737562 115122413 115122413

3 3.5 7 6.5 5 3.5 6.5 11.25 3.4 5.5 5.5 5.5 5 5.5 5.5 5 4.66667 3.8 5.5 10.5 12.25 6.25 5 4 4.33333 7 6.5 4.66667 6 5 8.5 6 5.66667 4.33333 6 5 4.5 12.5 10.5 9.5 4.2 6 6 4 5.33333 4 5.5 6.33333 7 9.5 3.6 3.75 4.25 5 4.75 7.5 4.6 8.5 5.5 6.5 4 4.75 4.25 5 13 6.66667 8 8.5 4.6 9 7 9 10.3333 6.25 7.66667 4.66667 5.5 3.5 5 5.5 5.8 3.25 5.5 5.5

. . intergenic . . intergenic . . intergenic ENSSSCT00000004949 FILIP1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000035901 CD109 intron ENSSSCT00000004956 CD109 intron ENSSSCT00000035127 CD109 intron ENSSSCT00000004957 SLC17A5 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000004963 SLC14A1 intron . . intergenic ENSSSCT00000004969 HAUS1 intron ENSSSCT00000004969 HAUS1 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000004977 SMAD2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000004978 CTIF intron ENSSSCT00000004978 CTIF intron ENSSSCT00000004978 CTIF intron ENSSSCT00000004978 CTIF intron . . intergenic . . intergenic . . intergenic ENSSSCT00000004980 . intron . . intergenic . . intergenic . . intergenic ENSSSCT00000004983 MYO5B intron ENSSSCT00000004990 SKA1 intron ENSSSCT00000004990 SKA1 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000004997 SMAD4 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000005003 POLI intron . . intergenic . . intergenic ENSSSCT00000005007 RAB27B intron ENSSSCT00000036505 TCF4 intron ENSSSCT00000036325 TCF4 intron

0.437 . -0.025 -0.049 . . . 0.163 . -0.302 -0.302 -0.302 . . . -0.3 . 0.921 0.617 0.047 0.017 . -0.095 0.11 . -0.039 . . . 0.621 -0.085 -0.275 -0.087 . 0.104 0.339 0.002 . 0.284 0.144 -0.18 . -0.008 . -0.281 . 0.234 . 0.447 -0.139 -0.171 0.307 -0.049 . . . . . 1.245 -0.126 . 0.109 0.256 0.047 0.088 -0.077 -0.268 -0.05 -0.096 -0.048 . 0.145 . 0.106 -0.045 0.268 -0.14 -0.025 . 0.312 0.123 0.031 0.086 0.086

781628 rs7909 rs786302860 rs792963588 rs790580784 rs790302266 rs792867680 rs793814351 383320 rs7906 . . . . . rs790666734 rs792886333 . 317624 rs7894 rs793464536 rs787710023 rs787636788 689852 rs7937 rs792765820 rs793579115 rs789664012 . . rs788419756 rs792020409 rs788189960 rs793249720 rs791501235 rs791610942 rs792121340 rs789005855 . rs787397115 rs789634613 rs787606811 rs790048786 rs788888514 rs786720488 rs790581810 rs793349418 . rs786897073 rs787631705 rs788830916 472519 rs7929 rs786987620 878689 rs7912 rs792007039 rs789045417 rs791288558 rs792216251 rs787939488 rs793540813 339554 rs7911 rs789540428 rs787805463 581936 rs7873 rs792222964 rs789912785 rs792405517 . rs786858880 rs791681359 240740 rs7900 . 381147 rs7938 rs789862355 rs789398152 rs793145327 608373 rs7924 663540 rs7890 rs790551132 rs792590366 . 349616 rs7887 rs787834152 rs791405627 482675 rs7873 rs793709834 . .

2 2 2 2 2 2 4 2 2 2 2 2 2 3 3 2 2 2 2 2 2 2 2 2 2 3 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 3 2 2 2 4 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2

AT.AT AAT.ATT AAT.ATT AG.CT AAAC.GTTT AG.CT AAAC.GTTT AT.AT ACC.GGT AAC.GTT AAAG.CTTT AAG.CTT AC.GT AC.GT AAGG.CCTT AGG.CCT AAG.CTT AT.AT AAAC.GTTT ACAT.ATGT AG.CT AGGG.CCCT AT.AT AT.AT AT.AT AC.GT AAAC.GTTT AT.AT AC.GT AC.GT AAT.ATT AGG.CCT AT.AT AG.CT AG.CT AAAAAC.GTTTTT AAAAAC.GTTTTT AC.GT AC.GT AAAT.ATTT AG.CT AAT.ATT AAC.GTT AT.AT AG.CT AG.CT AAAC.GTTT AAAAT.ATTTT AAAT.ATTT AAAC.GTTT AAAT.ATTT AAAAC.GTTTT AAAC.GTTT AC.GT ACAG.CTGT AAAC.GTTT ACAT.ATGT AAC.GTT AT.AT AC.GT AT.AT AAC.GTT AAAG.CTTT AAC.GTT AAACC.GGTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAAT.ATTTT AAAAAC.GTTTTT AAAC.GTTT AAAT.ATTT AT.AT AAAG.CTTT AC.GT AAAT.ATTT AAC.GTT AG.CT AAAT.ATTT AG.CT AAGG.CCTT AC.GT AAAC.GTTT AAC.GTT

1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

115122403 115178667 115178667 115383141 115932111 117491782 117840938 118140098 118302572 118358881 118547522 118713651 118926227 119054849 119174347 120045958 120098873 120157050 120284076 120302025 120414585 120461889 120641380 120654633 121512667 121528720 121633098 121738649 121807241 122303330 122369258 122529827 122664146 123304883 123304883 123313980 123313980 123391935 123391935 123434676 123563826 124116134 124172764 124532099 124578472 124614557 124660569 124664976 124698307 124712766 124763674 124963871 125470996 125614624 125721839 125964933 126019389 126097524 126160436 126295054 126403488 126496513 126553233 126713586 126860915 126929973 126929973 126929973 127061154 127531468 127687551 128141091 128246359 128577153 128583741 128784833 129119486 129218734 129278268 129359895 129616778 129781445 129792957 129847071

115122413 115178679 115178679 115383152 115932135 117491791 117840966 118140114 118302584 118358894 118547544 118713665 118926242 119054875 119174364 120045971 120098884 120157060 120284094 120302043 120414594 120461906 120641390 120654643 121512676 121528734 121633125 121738660 121807255 122303345 122369277 122529847 122664156 123304897 123304897 123314001 123314001 123391952 123391952 123434696 123563837 124116151 124172777 124532127 124578482 124614568 124660583 124664991 124698334 124712788 124763691 124963894 125471013 125614635 125721859 125964961 126019411 126097544 126160448 126295082 126403498 126496524 126553255 126713608 126860946 126929999 126929999 126929999 127061176 127531487 127687567 128141114 128246369 128577169 128583753 128784855 129119502 129218746 129278291 129359904 129616790 129781455 129792969 129847087

5.5 4.33333 4.33333 6 6.25 5 7.25 8.5 4.33333 4.66667 5.75 5 8 13.5 4.5 4.66667 4 5.5 4.75 4.75 5 4.5 5.5 5.5 5 7.5 7 6 7.5 8 6.66667 7 5.5 7.5 7.5 3.66667 3.66667 9 9 5.25 6 6 4.66667 14.5 5.5 6 3.75 3.2 7 5.75 4.5 4.8 4.5 6 5.25 7.25 5.75 7 6.5 14.5 5.5 4 5.75 7.66667 6.4 6.75 6.75 6.75 4.6 3.33333 4.25 6 5.5 4.25 6.5 5.75 5.66667 6.5 6 5 3.25 5.5 3.25 5.66667

ENSSSCT00000005009 TCF4 intron ENSSSCT00000036505 TCF4 intron ENSSSCT00000036325 TCF4 intron . . intergenic . . intergenic ENSSSCT00000005017 NARS promoter ENSSSCT00000005020 ANKDD1A intron . . intergenic ENSSSCT00000005027 ZNF609 intron ENSSSCT00000005027 ZNF609 intron . . intergenic ENSSSCT00000005035 . intron ENSSSCT00000005037 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000031480 . intron . . intergenic . . intergenic ENSSSCT00000028902 . intron ENSSSCT00000028902 . 3'utr . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000005056 NARG2 intron ENSSSCT00000025364 NARG2 intron ENSSSCT00000005056 NARG2 intron ENSSSCT00000025364 NARG2 intron ENSSSCT00000034155 ANXA2 intron ENSSSCT00000005057 ANXA2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000005065 FAM81A intron ENSSSCT00000005065 FAM81A intron . . intergenic . . intergenic ENSSSCT00000005066 MYO1E intron ENSSSCT00000005066 MYO1E intron ENSSSCT00000005066 MYO1E intron ENSSSCT00000005070 RNF111 intron . . intergenic ENSSSCT00000005077 . intron . . intergenic . . intergenic . . intergenic ENSSSCT00000027950 ALDH1A2 intron ENSSSCT00000024465 . intron . . intergenic . . intergenic ENSSSCT00000005079 MYZAP intron . . intergenic . . intergenic ENSSSCT00000005081H242-58J12 intron ENSSSCT00000005081H242-58J12 intron ENSSSCT00000034080H242-58J12 intron ENSSSCT00000035899H242-58J12 intron ENSSSCT00000005081H242-58J12 intron . . intergenic ENSSSCT00000028724 ZNF280D intron . . intergenic ENSSSCT00000029885 . intron . . intergenic . . intergenic ENSSSCT00000005088 PYGO1 intron ENSSSCT00000005093 RAB27A intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000005095 UNC13C intron ENSSSCT00000005095 UNC13C intron

0.086 0.117 0.117 -0.006 . 0.941 0.043 . 0.38 0.677 . 0.135 . . -0.09 -0.138 . . . 0.038 -0.005 -0.092 -0.018 -0.143 -0.045 0.197 -0.006 0.099 -0.121 -0.058 0.28 -0.253 -0.002 . . 0.202 0.202 0.005 0.005 -0.097 -0.012 0.125 -0.046 . -0.064 0.102 -0.13 . -0.101 0.418 -0.199 0.04 0.074 -0.31 -0.05 0.165 -0.015 -0.015 0.67 0.393 . 0.137 -0.307 -0.123 0.211 . . . 0.133 0.135 0.309 . 0.194 -0.144 -0.163 0.09 . 0.209 . 0.579 . 0.181 -0.032 .

. . . rs789809284 rs793832595 746752 rs7863 rs790324971 rs786926125 rs789740323 rs786367323 362916 rs7923 rs789783703 rs793876140 065577 rs7931 rs792695785 rs792798500 rs792332831 rs790021466 280168 rs7867 rs788842614 rs786398777 . rs791821700 rs793540228 rs790829188 rs788729051 rs786810350 611292 rs7886 . rs786858064 rs792523759 rs789947701 rs790856163 rs786862388 rs786862388 rs793477378 rs793477378 233630 rs7887 233630 rs7887 rs791372657 rs786910972 . rs790093526 rs788644968 rs793475618 . 939523 rs7879 . rs792867664 rs793746688 rs786287793 269572 rs7862 . rs793132949 rs792165466 rs790415115 581133 rs7917 rs790208815 rs792298211 rs792205332 rs787419712 rs793097661 rs792380013 rs786943153 rs790049578 rs790042938 rs790042938 rs790042938 rs789517459 rs786691686 rs787186319 rs791534032 154525 rs7879 . rs790998674 rs790598978 rs788469444 294120 rs7895 rs791571327 rs788337842 . rs792314728 . .

2 2 2 2 2 2 3 2 3 2 2 2 2 2 2 2 2 2 2 3 3 2 2 5 3 2 2 2 3 8 2 2 3 2 2 2 2 2 2 2 2 2 2 3 3 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 3 2 2 2 2 2 2 2 2 2 4 2 3 2 2 3 2 3 2 4 2 2

AC.GT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAAG.CTTTT AAAC.GTTT AC.GT AAAC.GTTT AAC.GTT AAGG.CCTT ACAT.ATGT AT.AT AAC.GTT AAAAC.GTTTT AAAAC.GTTTT AT.AT AAAC.GTTT AT.AT AACC.GGTT AAAAC.GTTTT AC.GT AC.GT AAAC.GTTT ATC.GAT AAAC.GTTT AAC.GTT AAC.GTT AC.GT AC.GT AC.GT AAAT.ATTT AAAT.ATTT AC.GT AAAT.ATTT AAT.ATT AAAC.GTTT AC.GT AG.CT AATG.CATT AAAAC.GTTTT ATC.GAT AGG.CCT AAAC.GTTT AAC.GTT AT.AT AC.GT AAAAT.ATTTT AG.CT AT.AT AG.CT AAAG.CTTT AAAC.GTTT AC.GT AC.GT AG.CT AAC.GTT AAAT.ATTT AAAAC.GTTTT AAAC.GTTT AT.AT AAGC.GCTT AAAT.ATTT AAAC.GTTT AC.GT AAAC.GTTT AAAG.CTTT AAAG.CTTT AAAG.CTTT AAAG.CTTT AAGGG.CCCTT AAG.CTT AAAC.GTTT AAAT.ATTT AC.GT AC.GT AGC.GCT AAC.GTT AAAT.ATTT AAAAC.GTTTT AAC.GTT AAAG.CTTT AAAG.CTTT AAAC.GTTT AAAT.ATTT

1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

129847543 130088643 130088643 130278811 130287302 130580645 130684716 130812912 132018054 132157932 132446344 132595155 132835053 133098178 133243899 133520794 134270026 134346735 134366223 134424181 134501137 134627686 135676894 135912391 135920264 136059356 136181735 136226815 136281060 136589391 136754175 136754175 137280383 137616509 137658629 137874450 137904531 137934728 137975676 138261322 138290999 138362227 138444536 138454916 139008614 139252838 139328335 139362732 139363422 139393253 139496192 139672521 139765876 139946796 140195013 140250250 140351942 140515798 140529589 140898877 141068932 141114594 141205239 141585216 141603737 141728541 141728541 141767356 141767356 141818305 141893949 141996154 142242687 142311289 142528849 142665492 142945665 142963277 143054985 143123580 143270561 143270561 143371157 143635070

129847565 130088659 130088659 130278830 130287316 130580675 130684733 130812931 132018072 132157952 132446370 132595165 132835077 133098206 133243921 133520803 134270039 134346747 134366234 134424201 134501150 134627695 135676914 135912410 135920294 136059377 136181753 136226840 136281074 136589400 136754202 136754202 137280397 137616528 137658642 137874464 137904542 137934743 137975706 138261348 138291016 138362242 138444550 138454930 139008643 139252847 139328362 139362748 139363440 139393266 139496207 139672544 139765885 139946809 140195022 140250267 140351962 140515826 140529604 140898906 141068954 141114612 141205253 141585226 141603751 141728560 141728560 141767374 141767374 141818329 141893962 141996167 142242713 142311303 142528859 142665508 142945691 142963299 143055008 143123598 143270582 143270582 143371183 143635088

11.5 4.25 4.25 5 3 7.75 9 5 6.33333 5.25 6.75 5.5 8.33333 5.8 4.6 5 3.5 6.5 3 4.2 7 5 5.25 6.66667 7.75 7.33333 6.33333 13 7.5 5 7 7 7.5 5 4.66667 3.75 6 8 7.75 5.4 6 5.33333 3.75 5 15 5 5.6 8.5 9.5 7 4 6 5 7 5 6 5.25 5.8 4 15 5.75 4.75 3.75 5.5 3.75 5 5 4.75 4.75 5 4.66667 3.5 6.75 7.5 5.5 5.66667 9 5.75 4.8 6.33333 5.5 5.5 6.75 4.75

ENSSSCT00000005095 ENSSSCT00000005095 ENSSSCT00000032068 ENSSSCT00000005095 ENSSSCT00000005095 . . ENSSSCT00000005096 ENSSSCT00000005097 ENSSSCT00000005098 ENSSSCT00000005103 ENSSSCT00000005104 ENSSSCT00000005107 ENSSSCT00000005113 ENSSSCT00000005111 ENSSSCT00000005116 . . . . . ENSSSCT00000005121 . . . . ENSSSCT00000005136 ENSSSCT00000005136 ENSSSCT00000005136 ENSSSCT00000005140 ENSSSCT00000029380 ENSSSCT00000005142 ENSSSCT00000005143 . ENSSSCT00000005147 . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000005157 . . ENSSSCT00000005162 . ENSSSCT00000028050 ENSSSCT00000025826 ENSSSCT00000005181 ENSSSCT00000025826 ENSSSCT00000005180 ENSSSCT00000025826 ENSSSCT00000025826 . . . ENSSSCT00000005185 ENSSSCT00000005193 ENSSSCT00000005201 ENSSSCT00000005202 ENSSSCT00000005205 ENSSSCT00000005206 ENSSSCT00000032277 ENSSSCT00000005209 ENSSSCT00000005210 .

UNC13C intron UNC13C intron . promoter UNC13C intron UNC13C intron . intergenic . intergenic . intron ONECUT1 intron FAM214A intron MYO5A intron MYO5C intron MAPK6 intron SCG3 intron TMOD2 intron GLDN intron . intergenic . intergenic . intergenic . intergenic . intergenic TRPM7 intron . intergenic . intergenic . intergenic . intergenic GALK2 intron GALK2 intron GALK2 intron SHC4 intron CEP152 intron CEP152 intron FBN1 intron . intergenic MYEF2 intron . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic SPATA5L1 intron . intergenic . intergenic DUOXA2 3'utr . intergenic . intron CASC4 intron EIF3J intron CASC4 intron CTDSPL2 intron CASC4 intron CASC4 intron . intergenic . intergenic . intergenic WDR76 intron STRC cds ZSCAN29 intron ADAL intron TGM5 intron EPB42 intron UBR1 intron UBR1 intron TTBK2 intron . intergenic

. . . 0.091 . . -0.071 -0.002 -0.075 0.228 0.009 -0.156 0.314 0.184 0.282 . . . 0.286 0.071 . 0.211 0.124 . 0.204 . -0.022 0.094 1.519 . 0.087 0.087 -0.077 0.176 0.242 . . 0.217 0.122 0.896 0.227 0.923 0.009 0.094 0.122 0.32 0.36 0.275 0.017 0.092 . . -0.049 . . . . . . . . 0.057 -0.244 . -0.083 . . 0.332 0.332 0.066 . 0.182 0.791 . . 0.427 0.44 . 0.194 -0.285 0.4 0.4 0.302 .

652912 rs7934 rs793329662 rs793329662 rs792422066 . rs789914029 rs793632274 rs791713190 rs786478979 . rs789746199 rs792269429 238225 rs7902 125829 rs7886 rs790653184 . rs791174336 rs793220282 . . rs793452660 . rs787335075 664520 rs7874 rs788332169 . rs792696986 . rs791602164 . 531853 rs7889 531853 rs7889 rs791275074 rs786371088 rs791703459 rs786582093 . 200224 rs7936 rs786525994 rs791359567 rs790469347 rs791604818 rs788707269 rs791243477 rs704391296 . 933318 rs7869 rs789147906 . . 260431 rs7906 rs787578220 . 123716 rs7889 . rs790189511 rs788051368 rs703663377 893023 rs7889 rs789898881 rs788614685 rs792509535 174743 rs7932 rs788651008 rs792090377 rs792611395 rs792611395 rs793077787 rs793077787 095256 rs7883 rs790172176 rs787182697 779283 rs7889 rs789409078 rs790891936 rs786894502 939312 rs7892 rs787330722 rs786450617 rs789279781 rs791433863 rs791433863 rs793617146 rs791408965

2 2 2 3 2 2 2 2 2 2 2 3 4 4 2 3 2 2 2 2 2 2 2 2 5 2 2 2 8 3 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 3 2 2 2 2 3 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2

AAC.GTT AAAAAC.GTTTTT AC.GT AAAT.ATTT AAAC.GTTT AAC.GTT AAAC.GTTT AAAC.GTTT AAAAT.ATTTT AGGG.CCCT AAAG.CTTT AGATCC.GGATC AT.AT AAT.ATT AAACT.AGTTT AAAC.GTTT AAAAC.GTTTT AAAAC.GTTTT AT.AT AAAC.GTTT AAAAC.GTTTT AAT.ATT AAG.CTT AATG.CATT AATG.CATT AT.AT AG.CT AAAAAG.CTTTTT AAC.GTT AT.AT AG.CT AT.AT AC.GT AT.AT AT.AT AG.CT AT.AT AAAAC.GTTTT AC.GT AC.GT AAAT.ATTT AAAAC.GTTTT AAAAC.GTTTT AAAC.GTTT AAAT.ATTT AAT.ATT AT.AT AAC.GTT AG.CT AC.GT AAAAC.GTTTT AC.GT AC.GT AAC.GTT AG.CT AAAAAT.ATTTTT AAAAAC.GTTTTT AC.GT AAAT.ATTT AAAT.ATTT AT.AT AC.GT AC.GT AAAC.GTTT AC.GT AAAAG.CTTTT AAAC.GTTT AC.GT AAAC.GTTT AC.GT AAAC.GTTT AG.CT AAAC.GTTT AC.GT AT.AT AAC.GTT AAAAG.CTTTT AAAC.GTTT AT.AT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AT.AT AG.CT

1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

143643702 143647975 143821806 143942296 144152998 144249755 144510463 144510463 144627944 145026193 146176423 146181902 146665914 146773948 146979366 147033637 147142239 147199769 147331572 147366943 147371381 147375806 147387886 147950123 148493013 148499712 148518103 148597037 148753162 148819045 148888633 148931206 148957124 149047892 149076683 149597650 149637454 149796299 149853167 150238861 150251839 150254564 150293785 150308264 150620332 151009854 151019445 151143794 151325689 151536059 151791751 151859918 151861239 151885423 151935641 152097439 152342234 152599168 152635065 152635065 152873848 153145273 153158181 153247867 153321263 153386424 153486451 153625926 153733206 153969007 154048315 154078047 154151676 154310111 154725207 154815235 154902756 155027752 155872821 155879448 155924299 155974660 156046282 156445683

143643730 143648002 143821820 143942310 144153025 144249772 144510487 144510487 144627959 145026207 146176445 146181923 146665926 146773964 146979382 147033656 147142263 147199789 147331582 147366965 147371399 147375819 147387903 147950150 148493035 148499721 148518119 148597071 148753178 148819055 148888647 148931233 148957140 149047905 149076695 149597659 149637467 149796321 149853176 150238873 150251854 150254587 150293813 150308278 150620349 151009867 151019478 151143810 151325700 151536076 151791775 151859928 151861248 151885442 151935660 152097461 152342272 152599177 152635082 152635082 152873857 153145296 153158196 153247885 153321282 153386438 153486463 153625939 153733225 153969021 154048335 154078058 154151699 154310124 154725218 154815249 154902782 155027770 155872832 155879469 155924311 155974683 156046292 156445697

9.66667 4.66667 7.5 3.75 7 6 6.25 6.25 3.2 3.75 5.75 3.66667 6.5 5.66667 3.4 5 5 4.2 5.5 5.75 3.8 4.66667 6 7 5.75 5 8.5 5.83333 5.66667 5.5 7.5 14 8.5 7 6.5 5 7 4.6 5 6.5 4 4.8 5.8 3.75 4.5 4.66667 17 5.66667 6 9 5 5.5 5 6.66667 10 3.83333 6.5 5 4.5 4.5 5 12 8 4.75 10 3 3.25 7 5 7.5 5.25 6 6 7 6 5 5.4 4.75 6 5.5 3.25 4.8 5.5 7.5

. . intergenic . . intergenic ENSSSCT00000005218 ZNF106 intron ENSSSCT00000005225 GANC intron ENSSSCT00000005228 PLA2G4F intron . . intergenic ENSSSCT00000005234 . intron ENSSSCT00000005241 . intron ENSSSCT00000022785 EHD4 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000005286 GPR176 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000005292 SPRED1 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000005293 TMCO5A intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000029836 DPH6 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000005301 . intron . . intergenic ENSSSCT00000005305ARHGAP11B cds ENSSSCT00000005305ARHGAP11B intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000030424 FAM169B intron . . intergenic ENSSSCT00000005310 PGPEP1L intron ENSSSCT00000005311 IGF1R intron ENSSSCT00000005311 IGF1R intron . . intergenic . . intergenic ENSSSCT00000005313 TTC23 intron ENSSSCT00000005313 TTC23 intron ENSSSCT00000005314 LRRC28 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000005327 CHSY1 intron . . intergenic . . intergenic

. 0.197 0.253 -0.067 -0.184 . 0.329 0.329 . 0.122 . -0.084 0.361 0.136 . 0.128 -0.164 0.044 0.216 0.272 0.322 . 0.104 0.009 0.139 0.173 . 0.276 . 0.135 2.815 0.234 3.645 0.482 0.169 . 0.2 0.375 1.314 1.888 0.621 0.412 0.435 0.074 0.131 . . 0.155 . 0.19 0.067 . . 0.485 0.176 -0.106 0.146 . . . 0.359 0.442 0.126 0.134 0.068 . . 0.067 -0.036 0.007 -0.069 -0.056 . . . 0.078 -0.172 -0.249 -0.012 . -0.007 -0.001 . .

rs793631431 rs788085651 670280 rs7933 rs787790810 035472 rs7894 rs787067792 633439 rs7903 633439 rs7903 rs786843519 rs788609414 402095 rs7933 127303 rs7937 308044 rs7109 rs793051324 rs787257115 rs790405531 rs788624398 rs789568756 rs793015433 rs793063140 rs790611037 . rs788860185 rs788041245 rs790577236 . . rs786372638 rs791863593 rs789973232 . rs788910442 823640 rs7884 rs788309855 rs786335864 . rs792735777 . . rs793145154 rs791163837 rs787388315 rs787846915 rs790636657 rs786997038 . . rs790501882 rs791304498 . 134360 rs7862 rs790169309 . . rs786736069 rs786658485 rs791149149 rs789623042 rs788980568 rs788980568 rs789410452 rs791222687 rs790240910 rs788230104 . rs789797939 rs793678263 221873 rs7882 rs786556133 rs786789619 018950 rs7902 357375 rs7935 rs788508336 rs791650790 rs790361806 rs793613062 rs789912694 892711 rs7870 142507 rs7938 rs793371509 rs788910619 rs790703459 810590 rs7872 .

2 2 4 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 3 2 2 2 2 2 3 2 3 2 2 2 2 2 2 2 3 2 2 4 2 2 4 3 2 2 2 2 2 2 4 4 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 3 2

AAAC.GTTT AT.AT AAC.GTT AG.CT AG.CT AG.CT AGATAT.ATATCT AAAT.ATTT AC.GT AAAC.GTTT AT.AT AC.GT AAAC.GTTT AC.GT AAAC.GTTT AAAAC.GTTTT AAAC.GTTT AAAG.CTTT AC.GT AC.GT AC.GT AT.AT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AG.CT AG.CT AG.CT AG.CT AAAC.GTTT AAT.ATT AAC.GTT AAAT.ATTT AAAAAT.ATTTTT AC.GT AC.GT AAAAGC.GCTTTT AAAC.GTTT AT.AT AC.GT AAAC.GTTT AAAT.ATTT AAAC.GTTT AT.AT AAAC.GTTT ATC.GAT AGGG.CCCT AAAC.GTTT AAAAC.GTTTT AGG.CCT AG.CT AAG.CTT AC.GT AAAC.GTTT AAAAT.ATTTT AATG.CATT AT.AT AAAAT.ATTTT AT.AT AC.GT AAAAT.ATTTT AT.AT AAT.ATT AG.CT AC.GT AC.GT AC.GT AT.AT AG.CT AAAC.GTTT AAAAAT.ATTTTT AAT.ATT AG.CT AC.GT AC.GT AGAT.ATCT AC.GT AAC.GTT AAG.CTT AT.AT AT.AT AGG.CCT

1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

156538581 156577123 156723902 157336713 157562807 157602843 157603016 158189442 158252861 158355549 158430195 158532975 158802221 158826152 158953479 159078067 159347439 159461779 160199442 160199442 160726571 161566603 161601430 161601430 161601430 161672512 161672512 161737307 161737307 162682422 162690223 162937743 163035112 163066837 163287225 163389289 163439034 163571655 163944029 163965180 164092182 164196505 164254714 164338445 164348524 164459041 164461132 164798142 165233636 165511379 165581724 166065938 166159160 166244280 166285160 166481782 166869375 167122718 167279724 167405203 167882325 168133223 168171992 168198082 168232363 168601575 168776246 169146782 169876852 170038296 170171635 170321890 170341859 170448568 170454081 170464352 170518582 170528236 170565703 170768783 170847703 170854504 170858462 170865338

156538594 156577149 156723918 157336730 157562817 157602856 157603036 158189466 158252875 158355573 158430205 158532987 158802254 158826166 158953505 159078086 159347462 159461801 160199452 160199452 160726587 161566618 161601450 161601450 161601450 161672524 161672524 161737317 161737317 162682440 162690243 162937765 163035134 163066855 163287246 163389308 163439047 163571667 163944055 163965208 164092191 164196516 164254744 164338464 164348550 164459050 164461146 164798178 165233653 165511401 165581751 166065950 166159188 166244310 166285176 166481797 166869398 167122741 167279734 167405229 167882345 168133242 168172011 168198094 168232380 168601584 168776259 169146793 169876866 170038308 170171651 170321916 170341883 170448597 170454093 170464367 170518591 170528250 170565723 170768798 170847719 170854515 170858474 170865353

3.5 13.5 5.66667 9 5.5 7 3.5 6.25 7.5 6.25 5.5 6.5 8.5 7.5 6.75 4 6 5.75 5.5 5.5 8.5 8 5.25 5.25 5.25 3.25 3.25 5.5 5.5 9.5 10.5 5.75 7.66667 6.33333 5.5 3.33333 7 6.5 4.5 7.25 5 6 7.75 5 6.75 5 3.75 12.3333 4.5 5.75 5.6 4.33333 14.5 10.3333 8.5 4 4.8 6 5.5 5.4 10.5 10 4 6.5 6 5 7 6 7.5 6.5 8.5 6.75 4.16667 10 6.5 8 5 3.75 10.5 5.33333 5.66667 6 6.5 5.33333

. . . . . . . . . . . . . . . . ENSSSCT00000005342 ENSSSCT00000032440 ENSSSCT00000005353 ENSSSCT00000022624 . ENSSSCT00000005362 ENSSSCT00000005362 ENSSSCT00000005360 ENSSSCT00000005363 ENSSSCT00000005360 ENSSSCT00000005363 ENSSSCT00000005360 ENSSSCT00000005363 . . . . . ENSSSCT00000025136 . . . ENSSSCT00000005365 . . . . . . . . . . . ENSSSCT00000005375 ENSSSCT00000005379 . . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000005390 . . . .

. . . . . . . . . . . . . . . . OTUD7A KLF13 APBA2 . . NFATC1 NFATC1 ATP9B ATP9B ATP9B ATP9B ATP9B ATP9B . . . . . . . . . ZNF516 . . . . . . . . . . . CNDP1 FBXO15 . . . . . . . . . . . . . . . . . . . . . . . . . . . TMX3 . . . .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron promoter intergenic intron intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic

. . -0.198 0.062 0.088 . . . . . . . . . . . . . 0.251 0.251 -0.137 . . . . . . . . . -0.281 -0.227 -0.242 . 0.012 . -0.045 . -0.519 -0.081 . 0.062 0.926 . 0.421 -0.123 . -0.351 -0.203 -0.211 -0.064 -0.347 -0.289 -0.063 -0.128 . . -0.176 -0.186 . . -0.043 0.07 0.056 . -0.263 0.045 0.371 -0.131 -0.314 -0.039 0.02 -0.04 . 0.294 -0.048 . -0.311 0.188 0.91 0.04 -0.161 . .

rs786470848 rs791157969 rs789733672 rs790244316 rs788438470 . 546068 rs7897 rs789332202 . rs793429476 rs788057471 rs788731524 rs790699565 . rs790236687 rs790362289 rs792550873 rs790639506 rs790568248 rs790568248 rs786723885 rs788854904 rs790337423 rs790337423 rs790337423 rs791089037 rs791089037 rs788364538 rs788364538 640763 rs7889 . rs788277955 rs791111207 367397 rs7863 rs789276387 383864 rs7886 926020 rs7917 . rs690563562 732906 rs7905 . rs792770799 rs692494150 rs793443539 . rs787864527 242823 rs7913 rs790802063 . rs792904995 rs790475319 . 668285 rs7912 rs789603253 . 797450 rs7874 rs791842718 rs793483334 . 638381 rs7916 . . 047078 rs7936 523928 rs7894 rs789925926 . 981612 rs7035 rs789118399 rs790362646 rs793800538 . rs791733318 742635 rs7895 rs786603503 rs787415394 028961 rs7888 rs789951961 rs788810646 rs790139300 rs791581063 rs787435088 815644 rs7900 698456 rs7889 rs793685331

3 2 2 2 2 2 2 2 4 2 2 2 2 7 2 2 2 2 3 3 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 3 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 4 2 3 2 3 2 2 2 2 4 2 2 2 2 2 2 2 2 2 3 2 2 2

AT.AT AC.GT AAAAT.ATTTT AAAAT.ATTTT AAAT.ATTT AAAC.GTTT AG.CT AAAAC.GTTTT AC.GT AC.GT AAC.GTT AT.AT AAAAC.GTTTT AT.AT AAAG.CTTT AT.AT AAAC.GTTT AC.GT AAT.ATT AAAT.ATTT AAAAC.GTTTT AAAT.ATTT AT.AT AAAC.GTTT AT.AT AAAAC.GTTTT AC.GT AT.AT AC.GT AT.AT AG.CT AAAAC.GTTTT AAAC.GTTT AC.GT AC.GT AAAC.GTTT AAAC.GTTT AAAC.GTTT AC.GT AT.AT AAAC.GTTT AC.GT AAAAG.CTTTT AAAAT.ATTTT AAAAC.GTTTT AAT.ATT AAT.ATT AG.CT AAAC.GTTT AC.GT AC.GT AAAC.GTTT AG.CT AT.AT AC.GT AC.GT ACAG.CTGT AAAC.GTTT AAAC.GTTT AAC.GTT AG.CT AAAC.GTTT AAAG.CTTT AAAC.GTTT AATG.CATT AC.GT AAAC.GTTT AAAC.GTTT AAC.GTT AC.GT AAT.ATT AAAAG.CTTTT AAAT.ATTT AG.CT AG.CT AG.CT AG.CT AAC.GTT AAC.GTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAAAC.GTTTTT

1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

171350655 171353292 171694381 171789096 171790761 171840646 171896511 172001952 172507364 172968941 173066013 173101498 173147904 173147987 173159897 173221795 173232072 173307841 173448163 173574612 173924154 173929750 174292009 174348080 174354756 174590982 174899125 174971280 174974799 175084494 175498517 176062518 176071265 176254328 176450792 176522062 176608228 176608228 176652757 176693494 176727809 176764225 177231963 177287503 177740137 178101164 178202438 178292479 178309217 178491253 178567203 178571671 178725070 178736924 178996543 179084651 179187730 179332717 179466820 179583516 179612428 179798167 180110591 180358208 180496477 180529638 180544811 180590683 180700035 180895939 180917186 180947395 180968770 180997071 180997071 181104316 181104316 181190076 182000106 183341070 183341070 183350924 183350924 183385859

171350666 171353305 171694401 171789119 171790789 171840657 171896523 172001969 172507386 172968970 173066026 173101509 173147923 173147997 173159934 173221820 173232083 173307851 173448174 173574624 173924170 173929769 174292022 174348103 174354766 174591009 174899154 174971291 174974809 175084506 175498526 176062542 176071288 176254341 176450819 176522076 176608246 176608246 176652767 176693505 176727827 176764243 177231988 177287532 177740160 178101185 178202451 178292491 178309234 178491271 178567216 178571698 178725089 178736936 178996558 179084670 179187748 179332739 179466851 179583532 179612440 179798185 180110619 180358234 180496494 180529663 180544836 180590697 180700054 180895952 180917211 180947417 180968787 180997086 180997086 181104325 181104325 181190098 182000127 183341088 183341088 183350945 183350945 183385884

6 7 4.2 4.8 7.25 3 6.5 3.6 11.5 15 4.66667 6 4 5.5 9.5 13 3 5.5 4 3.25 3.4 5 7 6 5.5 5.6 15 6 5.5 6.5 5 5 6 7 14 3.75 4.75 4.75 5.5 6 4.75 9.5 5.2 6 4.8 7.33333 4.66667 6.5 4.5 9.5 7 7 10 6.5 8 10 4.75 5.75 8 5.66667 6.5 4.75 7.25 6.75 4.5 13 6.5 3.75 6.66667 7 8.66667 4.6 4.5 8 8 5 5 7.66667 7.33333 4.75 4.75 5.5 5.5 4.33333

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000005391 CDH19 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000028414TNFRSF11A intron ENSSSCT00000005404TNFRSF11A intron . . intergenic ENSSSCT00000005405 KIAA1468 intron ENSSSCT00000005405 KIAA1468 intron ENSSSCT00000005405 KIAA1468 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000005413 CCBE1 intron ENSSSCT00000005413 CCBE1 intron ENSSSCT00000005415 LMAN1 intron ENSSSCT00000005418 . intron . . intergenic . . intergenic . . intergenic ENSSSCT00000005427 ALPK2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000005437 CLPX intron ENSSSCT00000005439 PARP16 promoter . . intergenic ENSSSCT00000005442 IGDCC3 intron . . intergenic ENSSSCT00000005441 IGDCC4 intron ENSSSCT00000025179 IGDCC4 intron ENSSSCT00000025793 PTPLAD1 intron ENSSSCT00000005446 PTPLAD1 intron . . intergenic . . intergenic ENSSSCT00000024115 MAP2K5 intron ENSSSCT00000036194 MAP2K5 intron ENSSSCT00000024115 MAP2K5 intron ENSSSCT00000036194 MAP2K5 intron ENSSSCT00000024115 MAP2K5 intron

. -0.042 . -0.038 . . -0.045 . -0.117 . -0.136 0.309 -0.079 -0.014 . 0.116 . -0.001 -0.093 0.298 -0.079 . . -0.133 -0.054 . 0.093 . -0.121 0.054 -0.116 0.114 0.086 0.173 . 0.238 0.236 0.236 -0.005 0.19 0.199 . 0.237 . -0.05 0.732 0.04 . 0.042 0.108 0.016 -0.008 . 0.213 0.165 -0.031 0.055 -0.114 -0.054 0 . -0.051 -0.183 -0.008 0.082 -0.008 . . 1.762 0.089 -0.064 -0.198 . 0.06 0.06 0.361 0.361 . . 1.841 1.841 . . 0.146

. . rs793207176 929074 rs7935 937287 rs7899 rs786880792 573178 rs7865 . rs788505708 . rs787918431 rs787999112 . rs791475690 rs788185469 116357 rs7902 813978 rs7907 707616 rs7919 rs789704377 rs789574028 . rs791642673 647431 rs7936 746845 rs7897 rs787073884 rs790203361 rs793217450 904696 rs7928 . 675316 rs7869 rs791138280 rs790528443 rs791904300 rs791711792 rs786301829 rs791968880 rs786887881 rs786887881 rs793039609 rs787342210 rs788429704 790591 rs7871 rs786808743 610110 rs7913 rs787373162 . 666211 rs7902 rs788486597 505324 rs7916 . rs793326887 rs712428425 298765 rs7913 rs786672848 757324 rs7929 137573 rs7937 . 608942 rs7880 rs790535280 495441 rs7863 rs787466048 rs791566553 rs793239157 333479 rs7907 . . rs791262304 rs792732569 rs786495487 rs791393309 rs791685764 727224 rs7938 rs789478509 rs690634157 rs690634157 rs793449393 rs793449393 476732 rs7913 rs788331612 rs793132451 rs793132451 rs791304572 rs791304572 rs790131245

4 4 2 2 2 2 2 2 2 2 2 3 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 3 2 2 3 3 2 2 4 2 2 2 3 2 3 2 2 2 3 2 2 2 2 2 2 2 2 2 3 2 2 2 3 2 2 2 2 2 2 2 3 2 2 2 2 2 2

AAAAAC.GTTTTT AAC.GTT AAC.GTT AAAC.GTTT AC.GT AC.GT AG.CT AAAT.ATTT AAAC.GTTT AC.GT AAAAC.GTTTT AAAAT.ATTTT AC.GT AC.GT AT.AT AAG.CTT AAAT.ATTT AAAC.GTTT AAC.GTT AAAAC.GTTTT ACAG.CTGT AC.GT AT.AT AAAT.ATTT AG.CT AAAAC.GTTTT AAAC.GTTT AAAAC.GTTTT AAAAC.GTTTT AT.AT AT.AT AT.AT AT.AT AT.AT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AAAT.ATTT AT.AT AC.GT AAC.GTT AAC.GTT AAT.ATT AC.GT AT.AT AGGG.CCCT AAC.GTT AC.GT AAAC.GTTT AC.GT AAAC.GTTT AAAC.GTTT AT.AT AT.AT AC.GT AT.AT AC.GT AC.GT AAAG.CTTT AGAT.ATCT AT.AT AAAC.GTTT AAAG.CTTT AT.AT AAAC.GTTT AAAAC.GTTTT AT.AT AT.AT AG.CT AT.AT AC.GT AAC.GTT AT.AT AT.AT AC.GT AT.AT AAAC.GTTT AAAC.GTTT AAC.GTT AT.AT AATG.CATT AC.GT AC.GT

1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

183385859 183408755 183408755 183413325 183441453 183441453 183536295 183570728 183620423 183668820 183700977 183800756 183879619 183879619 184634317 184660837 184865624 184922219 184991326 185126532 186422281 186455618 186623585 186714496 187470242 187496419 187706319 187855960 187855960 187885190 187885190 187947406 187947406 187947406 187977182 187977182 187977182 188350937 188392734 189035388 189379993 189441866 189506550 189560761 189655007 190254244 191191723 191413840 191582012 191740920 191891408 191893060 191905397 192161413 192218334 192242646 192454012 192669665 192677290 192705621 192721736 192906274 192915158 192947872 192952095 193508312 193532521 193583870 194192567 194488613 194719892 194968899 195138697 195540292 195640969 195700583 195816954 196021226 196038262 196677276 196996720 197863377 197931492 197944929

183385884 183408771 183408771 183413338 183441467 183441467 183536305 183570749 183620443 183668840 183700995 183800784 183879637 183879637 184634330 184660861 184865645 184922237 184991339 185126555 186422299 186455636 186623596 186714516 187470258 187496435 187706341 187855987 187855987 187885199 187885199 187947437 187947437 187947437 187977206 187977206 187977206 188350959 188392759 189035399 189380013 189441879 189506563 189560776 189655027 190254253 191191739 191413853 191582037 191740942 191891421 191893078 191905416 192161423 192218354 192242657 192454021 192669678 192677301 192705633 192721753 192906285 192915178 192947886 192952109 193508339 193532535 193583880 194192576 194488627 194719903 194968929 195138716 195540311 195640980 195700592 195816963 196021243 196038276 196677292 196996736 197863402 197931503 197944941

4.33333 5.66667 5.66667 3.5 7.5 7.5 5.5 5.5 5.25 10.5 3.8 5.8 9.5 9.5 7 8.33333 5.5 4.75 4.66667 4.8 4.75 9.5 6 5.25 8.5 3.4 5.75 5.6 5.6 5 5 16 16 16 6.25 6.25 6.25 4.6 6.5 6 10.5 4.66667 4.66667 5.33333 10.5 5 4.25 4.66667 13 5.75 7 4.75 5 5.5 10.5 6 5 7 6 3.25 4.5 6 5.25 3.75 7.5 7 3 5.5 5 7.5 6 15.5 6.66667 10 6 5 5 4.5 3.75 5.66667 8.5 6.5 6 6.5

ENSSSCT00000036194 ENSSSCT00000024115 ENSSSCT00000036194 ENSSSCT00000036194 ENSSSCT00000036194 ENSSSCT00000025567 ENSSSCT00000005468 . . . . ENSSSCT00000005470 ENSSSCT00000005469 ENSSSCT00000005470 . . ENSSSCT00000005478 . ENSSSCT00000022924 . . . . . . ENSSSCT00000023869 . ENSSSCT00000005492 ENSSSCT00000005493 ENSSSCT00000005492 ENSSSCT00000005493 ENSSSCT00000005492 ENSSSCT00000005493 ENSSSCT00000026271 ENSSSCT00000026271 ENSSSCT00000005492 ENSSSCT00000005493 ENSSSCT00000005496 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000005510 ENSSSCT00000025268 . . . . . . . ENSSSCT00000005517 . . .

MAP2K5 MAP2K5 MAP2K5 MAP2K5 MAP2K5 . SKOR1 . . . . . CLN6 . . . . . GLCE . . . . . . . . THSD4 THSD4 THSD4 THSD4 THSD4 THSD4 . . THSD4 THSD4 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . KLHL28 FAM179B . . . . . . . . . . .

intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intron 3'utr intron intergenic intergenic intron intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intron intron intron intron intron intron intron 3'utr intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic

0.146 0.149 0.149 0.296 0.019 0.019 -0.129 . . 0.147 -0.013 . 0.962 0.962 0.211 . -0.34 0.069 0.458 -0.204 -0.201 -0.077 -0.13 0.099 0.002 0.268 0.159 0.081 0.081 . . 0.167 0.167 0.167 1.155 1.155 1.155 -0.054 . 0.113 0.14 . . 0.08 . -0.001 -0.193 0.061 -0.042 0.033 0.233 . . -0.037 . . -0.285 . . . . 0.128 . . . -0.254 . . . . . 0.201 . 0.253 0.279 0.45 0.337 0.241 . 0.003 0.057 . -0.053 -0.064

rs790131245 rs788845914 rs788845914 rs793250612 rs791711193 rs791711193 . . rs699586630 rs789935561 rs788031561 rs787486974 rs793746344 rs793746344 . rs789485578 rs792883147 943127 rs7888 rs791768499 rs791784911 rs786567202 . . rs793443737 rs789499584 rs792005652 rs793027883 rs790257501 rs790257501 . . rs788500093 rs788500093 rs788500093 rs789958075 rs789958075 rs789958075 673123 rs7882 rs792353224 rs792426573 436330 rs7863 rs788988144 933736 rs7917 . . rs707784002 . 954526 rs7873 rs792561874 rs793338035 970907 rs7918 rs789762398 rs790644929 . rs789457805 . . 381653 rs7928 133315 rs7918 rs789996090 . rs792005388 rs788792217 rs793717397 624459 rs7923 rs792092763 rs789763699 rs787019036 . rs787784979 rs786319888 405783 rs7883 rs786512632 rs791625421 rs788880404 . rs791610709 rs788683265 rs789677907 rs792974690 . 054171 rs7921 rs790533878 rs791920090

2 2 2 2 2 2 3 2 2 2 2 2 2 2 3 2 2 2 2 2 2 3 4 2 2 2 2 3 3 2 2 2 2 2 2 2 2 2 2 2 3 3 2 2 3 3 2 2 2 2 2 2 2 4 2 2 3 4 2 2 4 2 2 3 2 2 2 2 3 2 2 3 2 2 3 3 2 2 3 3 4 2 3 2

AAAC.GTTT AAAC.GTTT AT.AT AAAC.GTTT AAT.ATT AAAC.GTTT AAC.GTT AC.GT AAC.GTT AAC.GTT AAAC.GTTT AAAC.GTTT AAT.ATT AC.GT AG.CT AGC.GCT AC.GT AAAAT.ATTTT AG.CT AC.GT AAC.GTT AT.AT AT.AT AAAT.ATTT AAAT.ATTT AAC.GTT AAG.CTT AAAAC.GTTTT AC.GT AG.CT AG.CT AC.GT AT.AT AG.CT ATC.GAT AAAC.GTTT AAAAC.GTTTT AT.AT AT.AT AAAC.GTTT AAC.GTT AAC.GTT AAAC.GTTT AGC.GCT AG.CT AAAAC.GTTTT AAAC.GTTT AAAAC.GTTTT AAAAC.GTTTT AC.GT AAC.GTT AG.CT AAGG.CCTT AAG.CTT AAAT.ATTT AAC.GTT AAG.CTT AT.AT AT.AT AATG.CATT AAT.ATT AAG.CTT AAAT.ATTT AT.AT AAT.ATT AAAG.CTTT AAC.GTT AAAC.GTTT AAAT.ATTT AG.CT AC.GT AG.CT AAAC.GTTT AATT.AATT AAG.CTT AAAT.ATTT AG.CT AAT.ATT AG.CT AG.CT AT.AT AC.GT AAAAAC.GTTTTT ACCT.AGGT

1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

197954676 198008393 198254633 198805835 199762214 199875331 200330787 200602609 200939159 200939159 201078448 201078448 201225055 201247526 201352926 201470442 201606825 201811107 202057531 202215971 202318531 202462682 202462682 202481560 202481560 202726988 202875596 202883727 202891414 203043706 203100535 203706580 204166497 204447640 204511141 204616524 204771869 204903892 204907741 204978256 205407371 205414840 205491318 205517979 205645061 205713396 205764701 205929633 205930807 206135419 206244502 206368580 206459729 206519216 206544031 206593487 206655708 206771264 206862083 207149186 207218733 208077876 208180167 208632597 208710310 208719834 208749320 208778179 209535158 209926313 210116887 210124832 210237958 210484658 210550666 210592544 210708214 211165013 211365904 211499520 211782165 212767376 212782017 213029287

197954695 198008423 198254644 198805869 199762225 199875346 200330809 200602619 200939178 200939178 201078470 201078470 201225068 201247538 201352936 201470453 201606848 201811130 202057543 202215987 202318551 202462692 202462692 202481583 202481583 202727001 202875621 202883749 202891436 203043722 203100550 203706595 204166514 204447649 204511156 204616539 204771889 204903901 204907754 204978278 205407390 205414855 205491334 205518000 205645070 205713410 205764717 205929653 205930828 206135434 206244513 206368593 206459753 206519230 206544053 206593504 206655721 206771276 206862093 207149218 207218748 208077890 208180190 208632610 208710321 208719848 208749333 208778201 209535192 209926325 210116899 210124841 210237977 210484674 210550684 210592577 210708226 211165026 211365933 211499530 211782176 212767394 212782037 213029308

5 7.75 6 8.75 4 4 7.66667 5.5 6.66667 6.66667 5.75 5.75 4.66667 6.5 5.5 4 12 4.8 6.5 8.5 7 5.5 5.5 6 6 4.66667 8.66667 4.6 11.5 8.5 8 8 9 5 5.33333 4 4.2 5 7 5.75 6.66667 5.33333 4.25 7.33333 5 3 4.25 4.2 4.4 8 4 7 6.25 5 5.75 6 4.66667 6.5 5.5 8.25 5.33333 5 6 7 4 3.75 4.66667 5.75 8.75 6.5 6.5 5 5 4.25 6.33333 8.5 6.5 4.66667 15 5.5 6 9.5 3.5 5.5

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000005523 DNAAF2 intron ENSSSCT00000005531 SOS2 intron ENSSSCT00000005536 . intron ENSSSCT00000005539 ABHD12B intron ENSSSCT00000023698 ABHD12B intron ENSSSCT00000005541 TRIM9 intron ENSSSCT00000022907 TRIM9 intron ENSSSCT00000028405 TMX1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000027583 . intron ENSSSCT00000005553 ERO1L intron ENSSSCT00000027583 . intron ENSSSCT00000005553 ERO1L intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000024259 SAMD4A intron ENSSSCT00000024259 SAMD4A intron ENSSSCT00000024259 SAMD4A intron . . intergenic . . intergenic ENSSSCT00000005571 MAPK1IP1L promoter . . intergenic . . intergenic . . intergenic ENSSSCT00000005577 KTN1 intron ENSSSCT00000005577 KTN1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000029724 PELI2 intron . . intergenic . . intergenic ENSSSCT00000005579 TMEM260 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000022854 RTN1 intron ENSSSCT00000005600 LRRC9 intron ENSSSCT00000005600 LRRC9 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000005616 PKC intron . . intergenic . . intergenic ENSSSCT00000005628 NTRK3 intron

. . -0.018 . . 0.534 . 0.187 0.191 0.191 0.219 0.219 0.121 . 0.023 0.088 0.153 . 1.153 0.169 0.08 . . 0.339 0.339 0.122 -0.3 0.419 0.111 0.116 . 0.305 0.159 0.161 0.076 -0.1 0.912 0.713 . 0.409 0.101 0.108 1.083 0.472 . . 0.317 0.203 -0.021 -0.064 . . 0.305 0.078 0.17 0.047 1.128 0.121 . -0.038 0.084 . 0.11 0.512 0.132 . 0.068 0.123 -0.024 . 0.16 0.241 0.165 0.193 . . 0.161 . 0.1 -0.233 0.268 0.033 . 0.035

018262 rs7931 rs791781768 361785 rs7889 592011 rs7911 . rs789743133 323261 rs7909 . rs789750270 rs789750270 rs788550861 rs788550861 rs790530994 . . . rs793833170 rs791088850 . rs788024309 352276 rs7895 rs791431380 rs791431380 rs789361988 rs789361988 rs791353349 rs789440178 rs789929565 001869 rs7917 042342 rs7879 rs691587047 975065 rs7874 909110 rs7931 rs790935450 rs787804043 926414 rs7922 506037 rs7937 . 449046 rs7876 rs787778147 rs788870542 352414 rs7898 rs786498266 315934 rs7937 rs789073244 rs792757370 187259 rs7921 rs786536401 rs787544441 . rs792205585 rs788263694 417692 rs7895 rs790785391 703454 rs7894 . 661931 rs7879 rs790093025 rs789719415 704162 rs7906 rs792124243 rs792132198 rs694024205 rs788199673 rs787409374 155505 rs7874 508579 rs7914 415876 rs7872 rs790848758 013079 rs7865 rs791548185 . rs787661908 rs793356513 rs787730643 . . rs790808553 rs792968484 . rs713454280 rs791448163 814404 rs7937 rs792426465

2 2 2 2 4 2 2 3 2 2 2 2 2 3 3 2 2 2 5 3 2 2 2 2 2 2 4 2 4 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 4 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2

ATC.GAT AG.CT ATC.GAT AAC.GTT AAC.GTT AAC.GTT AAAT.ATTT AT.AT AC.GT AAAC.GTTT AAT.ATT AGATAT.ATATCT AC.GT AT.AT AG.CT AC.GT AAGG.CCTT AATC.GATT AAAC.GTTT AC.GT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AGG.CCT AT.AT AG.CT AG.CT AC.GT AC.GT AC.GT AC.GT AAAAT.ATTTT AAAAT.ATTTT AAAATT.AATTTT AAG.CTT AC.GT AAAC.GTTT AT.AT AC.GT AT.AT AT.AT AAAC.GTTT AAAC.GTTT AG.CT AAC.GTT ACAT.ATGT AT.AT AAAT.ATTT AG.CT AT.AT AAAT.ATTT AC.GT AC.GT AT.AT AG.CT AT.AT AATC.GATT AAAC.GTTT AG.CT AG.CT AAT.ATT AC.GT AAC.GTT AAATT.AATTT AG.CT AAAC.GTTT AC.GT AC.GT AC.GT AAAAAC.GTTTTT AC.GT AAAAAG.CTTTTT AAAC.GTTT AG.CT AC.GT ACCC.GGGT AAAAC.GTTTT AATG.CATT AAAT.ATTT AC.GT AAAC.GTTT AAAC.GTTT AG.CT AT.AT

1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

213044664 213076717 213120147 213742957 213743642 214050188 214201215 214275929 214297370 214360158 214422808 214636492 214800703 214895023 214941374 215049402 215322847 215413963 215501516 215749522 216098066 216108849 216130083 216952038 217479920 217502675 217533612 218472319 218472319 218472319 218472319 218578907 218578907 218980835 219029074 219817655 219886165 219932429 220253323 220293658 220385436 220746731 220970674 221033521 221245641 221489944 221495167 221516759 221646071 221923773 222260416 222477096 223010462 223694787 223695304 223952510 224087266 224138972 224227937 224371169 224389797 225582074 225677718 225712461 225848812 226229551 226666639 226712261 227091879 227233477 227425344 227433448 227581108 228027148 228066062 228162439 228337478 229009264 229045143 229849194 230414008 230431837 230476385 230583643

213044680 213076729 213120159 213742972 213743658 214050200 214201239 214275938 214297382 214360193 214422819 214636520 214800715 214895037 214941384 215049416 215322874 215413995 215501531 215749535 216098082 216108861 216130109 216952049 217479930 217502685 217533624 218472331 218472331 218472331 218472331 218578939 218578939 218980858 219029099 219817666 219886187 219932449 220253333 220293682 220385459 220746750 220970692 221033537 221245652 221489966 221495179 221516775 221646084 221923783 222260434 222477108 223010472 223694799 223695316 223952519 224087286 224139002 224227948 224371183 224389811 225582083 225677743 225712475 225848826 226229565 226666667 226712272 227091889 227233499 227425367 227433473 227581124 228027159 228066076 228162455 228337507 229009300 229045162 229849224 230414026 230431857 230476395 230583653

5.66667 6.5 4.33333 5.33333 5.66667 4.33333 6.25 5 6.5 9 4 4.83333 6.5 7.5 5.5 7.5 7 8.25 4 7 3.4 3.25 6.75 4 5.5 5.5 6.5 6.5 6.5 6.5 6.5 6.6 6.6 4 8.66667 6 5.75 10.5 5.5 12.5 12 5 4.75 8.5 4 5.75 6.5 4.25 7 5.5 4.75 6.5 5.5 6.5 6.5 5 5.25 7.75 6 7.5 5 5 8.66667 3 7.5 3.75 14.5 6 5.5 3.83333 12 4.33333 4.25 6 7.5 4.25 6 9.25 5 15.5 4.75 5.25 5.5 5.5

ENSSSCT00000005628 ENSSSCT00000005628 ENSSSCT00000005628 . . . . . . . . . . . . . . . . ENSSSCT00000005632 . . . . . . . ENSSSCT00000035816 ENSSSCT00000036581 ENSSSCT00000005647 ENSSSCT00000033502 ENSSSCT00000005649 ENSSSCT00000005650 . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000005663 . . . . . . ENSSSCT00000028872 . ENSSSCT00000005694 ENSSSCT00000005695 ENSSSCT00000005695 . ENSSSCT00000005700 . . . . . . . . . ENSSSCT00000031467 . . . ENSSSCT00000005713

NTRK3 NTRK3 NTRK3 . . . . . . . . . . . . . . . . ER2 . . . . . . . TEK TEK TEK TEK IFT74 LRRC19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . MLLT3 SLC24A2 SLC24A2 . DENND4C . . . . . . . . . . . . . .

intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intron intron intron intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intron

0.018 0.233 0.084 . . -0.103 0.125 -0.168 -0.06 -0.055 -0.109 -0.042 -0.006 0.096 0.29 0.163 -0.029 0.58 -0.168 0.085 -0.604 0.15 0.344 0.014 0.379 -0.062 0.559 -0.058 -0.058 -0.058 -0.058 0.223 0.223 . 0.09 0.097 0.194 0.067 . . -0.056 . -0.047 . 0.049 . 0.16 0.327 . 0.319 0.044 -0.13 0.556 . . . . 0.06 0.003 0.019 0.287 . 0.361 . 0.26 0.066 0.307 -0.038 . . . 0.032 0.032 . 0.065 -0.162 0.65 -0.016 -0.114 4.063 0.001 0.005 0.505 0.025

rs790639664 . . . . 533184 rs7876 281426 rs7888 . rs793853763 rs788724601 rs791192165 rs791979364 rs790386629 rs793784045 . rs787940574 374749 rs7913 rs787057807 rs787393159 rs792130290 rs787045859 rs792767040 385682 rs7865 . rs787755021 rs793082133 . 816373 rs7888 816373 rs7888 816373 rs7888 816373 rs7888 rs787837741 rs787837741 062069 rs7880 rs786951786 rs792790458 rs791638553 rs792687691 . 071747 rs7902 164616 rs7886 rs788047428 rs790268891 293362 rs7884 rs792424746 rs786743081 369913 rs7865 rs787912607 487236 rs7923 rs790574856 rs790914660 . . 763147 rs7887 rs793684259 . 463242 rs7882 . . 610519 rs7925 rs791752331 . rs791536108 117541 rs7911 187877 rs7934 rs790641846 152378 rs7916 rs793039930 . rs792318383 372215 rs7937 rs787814633 rs793671225 rs789047047 533212 rs7031 . 025188 rs7926 345278 rs7895 rs787579796 rs788979451 rs793752163 rs788327913 . .

2 4 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 4 3 3 3 3 2 2 2 2 2 2 2 2 2 2 2 2 2 4 3 3 2 2 2 2 2 2 2 2 2 2 2 4 2 2 4 2 2 3 3 2 2 3 2 2 2 2 5 4 2 2 2 2 2 2 2 2 2

ACAC.GTGT AAAC.GTTT AAAT.ATTT AC.GT AG.CT AAAC.GTTT AAC.GTT AAAT.ATTT AAAAT.ATTTT AC.GT AAAAT.ATTTT AAAC.GTTT AG.CT AAAC.GTTT AAAAT.ATTTT AC.GT AT.AT AT.AT ACAG.CTGT AAAC.GTTT AT.AT AT.AT AC.GT AT.AT AAAAG.CTTTT AG.CT AAAC.GTTT AG.CT AT.AT AAAC.GTTT AAAAC.GTTTT AC.GT AT.AT AT.AT AC.GT AAG.CTT AAAC.GTTT AC.GT AT.AT AC.GT AAAC.GTTT AAAT.ATTT AT.AT AC.GT AAAC.GTTT AAC.GTT ACT.AGT AT.AT AT.AT AAAC.GTTT AC.GT AAG.CTT AAAAAC.GTTTTT AG.CT AC.GT AC.GT AC.GT AT.AT AC.GT AAAC.GTTT AGGGG.CCCCT ACAT.ATGT AT.AT AT.AT AT.AT AAT.ATT AAC.GTT AC.GT AAAAC.GTTTT AT.AT AC.GT AAAC.GTTT AAAAC.GTTTT AAAC.GTTT AC.GT AT.AT AAAT.ATTT AT.AT AC.GT AC.GT AAAT.ATTT AAAT.ATTT AAAAAC.GTTTTT AAAC.GTTT

1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

230649318 230706869 231360462 231521164 231839662 231871825 231879602 232449039 232526550 232551618 232625268 232787936 232912746 233156056 233306639 233961246 234056948 234090450 234175813 234470007 234497374 235084062 235113287 235792274 235891542 236044165 237038149 237144009 237250677 237863323 238252553 238351466 239200162 239774830 239986002 240474816 240601522 240802447 240861131 240880337 241247951 241704933 241967279 242411760 242566826 242771010 242779629 242846964 242872912 243100746 243408097 243431999 243692888 243696491 243966142 243966142 244075335 244096162 244435177 244523078 244599002 245532578 245701774 245711846 245745321 246494633 246775741 247134011 247424232 247457282 247564684 247697358 247829305 247878018 248031213 248318662 248328596 248619841 248718751 248718751 248738522 248738522 248974175 249128415

230649356 230706899 231360478 231521176 231839673 231871844 231879621 232449061 232526576 232551627 232625287 232787957 232912773 233156078 233306654 233961281 234056960 234090471 234175824 234470033 234497386 235084081 235113299 235792305 235891567 236044182 237038167 237144023 237250688 237863340 238252575 238351478 239200186 239774859 239986022 240474833 240601547 240802458 240861142 240880351 241247973 241704954 241967299 242411772 242566848 242771023 242779644 242846980 242872921 243100765 243408111 243432024 243692915 243696509 243966151 243966151 244075349 244096171 244435219 244523093 244599016 245532595 245701785 245711855 245745331 246494644 246775758 247134020 247424254 247457293 247564694 247697372 247829323 247878036 248031223 248318671 248328613 248619851 248718762 248718762 248738536 248738536 248974201 249128433

9.75 7.75 4.25 6.5 6 5 6.66667 5.75 5.4 5 4 5.5 14 5.75 3.2 18 6.5 11 3 6.75 6.5 10 6.5 16 5.2 9 4.75 7.5 6 4.5 4.6 6.5 12.5 15 10.5 6 6.5 6 6 7.5 5.75 5.5 10.5 6.5 5.75 4.66667 5.33333 8.5 5 5 7.5 8.66667 4.66667 9.5 5 5 7.5 5 21.5 4 3 4.5 6 5 5.5 4 6 5 4.6 6 5.5 3.75 3.8 4.75 5.5 5 4.5 5.5 6 6 3.75 3.75 4.5 4.75

ENSSSCT00000005713 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000005723 MPDZ intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000005730 . intron ENSSSCT00000005730 . intron ENSSSCT00000005730 . intron . . intergenic . . intergenic ENSSSCT00000005738 MLANA intron ENSSSCT00000005744 PDL1 intron . . intergenic ENSSSCT00000005748 JAK2 intron ENSSSCT00000005748 JAK2 intron . . intergenic . . intergenic ENSSSCT00000005752 CDC37L1 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000005757 GLIS3 intron ENSSSCT00000005758 GLIS3 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000005766 SMARCA2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000005769 . intron ENSSSCT00000005769 . intron ENSSSCT00000005774 DOCK8 intron ENSSSCT00000005774 DOCK8 intron . . intergenic . . intergenic ENSSSCT00000005777 PGM5 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000027067 FXN intron ENSSSCT00000005781 TJP2 intron ENSSSCT00000027067 FXN intron ENSSSCT00000005781 TJP2 intron ENSSSCT00000005783 FAM189A2 intron . . intergenic

. . 0.21 0.104 0.075 . 0.015 0.238 -0.183 -0.326 0.206 0.443 -0.211 -0.109 -0.219 0.446 . 0.443 . 0.016 -0.068 . . . . 0.025 -0.052 0.019 . 0.836 . 0.031 -0.211 . 0.113 0.071 . 0.253 2.917 0.378 0.13 0.044 . 0.11 . 0.061 . 0.384 . 0.19 -0.045 0.296 . . 0.561 0.561 . 0.238 0.15 . 0.056 0.026 0.24 0.017 0.097 -0.073 . -0.158 0.007 -0.078 0.102 0.206 . . 0.138 . -0.05 0.058 . . 1.356 1.356 . -0.333

rs793171914 rs787040612 905140 rs7930 . . rs793528775 rs786596121 rs791927119 352848 rs7911 . rs789525219 rs791601012 . 973183 rs7925 rs792299827 rs787775959 rs792552518 . rs789346276 262712 rs7881 . 163564 rs7925 . rs791961786 . rs792186575 rs791027208 rs787498964 rs788071634 rs792541702 . . 994070 rs7889 . . 141105 rs7928 rs792429494 . rs786938690 rs792139077 rs791760118 rs792519218 026367 rs7888 . 360500 rs7865 rs790680260 . . . rs790369434 rs788067360 263228 rs7866 . rs788325201 rs788442659 rs788442659 rs791346242 . rs787391441 rs788551564 rs790844808 rs793639137 rs788909449 rs786301555 rs692217869 rs789546339 rs789522032 rs699871035 685949 rs7901 356829 rs7938 rs787608350 113728 rs7908 648152 rs7884 rs790391453 . rs786921956 rs789370282 rs695132593 166570 rs7882 166570 rs7882 rs790489107 rs790489107 rs791108184 rs790909030

3 2 2 3 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 3 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 6 3 2 2 2 2 3 2 2 2 2 3 2 4 3 2 3 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 4 2 2 2 2 2 3 3 2 2

AAT.ATT AC.GT AAAC.GTTT AATG.CATT AG.CT AAAAC.GTTTT AT.AT AC.GT AT.AT AC.GT AAC.GTT AC.GT AC.GT AT.AT AAT.ATT AAGG.CCTT AG.CT AT.AT AC.GT AAAC.GTTT AC.GT AG.CT AC.GT AAAAC.GTTTT AAAT.ATTT AT.AT AAT.ATT AC.GT AG.CT AT.AT AC.GT AAAC.GTTT AATG.CATT AAAAC.GTTTT AAAAAC.GTTTTT AG.CT AAAAT.ATTTT AATG.CATT AAAC.GTTT AG.CT AGATAT.ATATCT AAAC.GTTT AG.CT ACAT.ATGT AATC.GATT AT.AT AC.GT AT.AT AT.AT AAAAC.GTTTT AAAC.GTTT AAAAC.GTTTT AAAC.GTTT AAAAC.GTTTT AAAT.ATTT AC.GT AC.GT AAGAG.CTCTT AG.CT ATCCCC.GGGGA AC.GT AAAC.GTTT AAAG.CTTT AT.AT AAAT.ATTT AC.GT AAAC.GTTT AC.GT AAGG.CCTT AC.GT AAAC.GTTT AAAC.GTTT AC.GT AAT.ATT AAAC.GTTT ACC.GGT AAAAGG.CCTTTT AAC.GTT ACAT.ATGT AAAC.GTTT AAAT.ATTT ACCT.AGGT AAAG.CTTT AAAC.GTTT

1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

249236709 249418897 249525150 249528006 249653827 249877356 250439790 250548949 250652573 250796974 250907551 250971063 250995438 251244818 251362325 251624335 251784811 251895491 251922983 251982959 251999913 252723742 252776100 252914639 253051200 253111632 253113130 253593166 253600941 254031336 254159280 254566628 254620865 254671474 254750669 254789402 254790145 255071859 255330464 255483015 255539086 255552880 255576468 255660920 255833271 256209346 256264906 256281712 256290092 256351327 256705340 256766231 257000970 257037351 257203942 257256139 257295261 257584258 257703587 257818486 257820102 257840482 257942074 258233761 258309934 258359134 258446892 258522622 258544900 259032204 259407745 259959067 260006911 260338753 260486784 260584626 260721999 260725490 261736431 261820417 262055649 262149642 262435099 262443239

249236722 249418922 249525170 249528029 249653836 249877372 250439802 250548959 250652591 250796990 250907566 250971073 250995456 251244828 251362342 251624356 251784820 251895510 251922997 251982978 251999923 252723752 252776109 252914664 253051212 253111643 253113143 253593175 253600953 254031346 254159294 254566655 254620887 254671492 254750697 254789417 254790169 255071872 255330499 255483029 255539122 255552899 255576489 255660944 255833294 256209361 256264917 256281747 256290122 256351348 256705358 256766256 257000992 257037374 257203960 257256152 257295272 257584277 257703599 257818509 257820124 257840510 257942095 258233782 258309952 258359150 258446907 258522646 258544920 259032214 259407759 259959094 260006931 260338770 260486804 260584660 260722017 260725509 261736458 261820444 262055670 262149664 262435113 262443261

4.66667 13 5.25 6 5 3.4 6.5 5.5 9.5 8.5 5.33333 5.5 9.5 5.5 6 5.5 5 10 7.5 5 5.5 5.5 5 5.2 3.25 6 4.66667 5 6.5 5.5 7.5 7 5.75 3.8 4.83333 8 5 3.5 9 7.5 6.16667 5 11 6.25 6 8 6 18 15.5 4.4 4.75 5.2 5.75 4.8 4.75 7 6 4 6.5 4 11.5 7.25 5.5 11 4.75 8.5 4 12.5 5.25 5.5 3.75 7 10.5 6 5.25 11.6667 3.16667 6.66667 7 7 5.5 5.75 3.75 5.75

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000022526 . intron ENSSSCT00000005792 . intron ENSSSCT00000005792 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000026837 C9orf85 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000005803 RORB intron ENSSSCT00000005803 RORB intron ENSSSCT00000005804 TRPM6 intron ENSSSCT00000005804 TRPM6 intron ENSSSCT00000005804 TRPM6 intron ENSSSCT00000005808 OSTF1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000024731 PCSK5 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000005813 PRUNE2 intron . . intergenic . . intergenic ENSSSCT00000005817 VPS13A intron ENSSSCT00000005817 VPS13A intron ENSSSCT00000005819 GNA14 intron ENSSSCT00000005819 GNA14 intron ENSSSCT00000005819 GNA14 intron . . intergenic . . intergenic ENSSSCT00000005824 PSAT1 intron ENSSSCT00000005824 PSAT1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000005828 TLE1 intron . . intergenic . . intergenic . . intergenic . . intergenic

0.013 0.153 0.097 0.055 . . . 0.508 0.011 -0.16 0.044 0.282 . . 0.196 0.095 0.185 . . . . 0.073 -0.093 -0.009 -0.003 . . -0.02 -0.214 0.338 -0.064 -0.209 0.095 0.908 0.193 -0.009 -0.035 0.3 0.03 . . . 0.056 0.345 . . -0.347 . . 0.387 -0.008 0.363 0.056 . -0.198 . 0.191 0.498 0.046 2.169 -0.172 0.126 -0.042 . . 0.146 0.034 1.472 0.062 1.851 0.117 -0.061 0.117 0.353 . -0.015 0.047 0.13 0.513 0.312 -0.002 0.223 0.15 0.203

rs791701819 . rs787553139 037784 rs7913 rs788910759 . 154485 rs7892 rs696600665 . . 800332 rs7921 575181 rs7903 rs790124857 rs792453852 rs789509170 rs790048187 . rs789192313 rs786877099 937391 rs7906 . rs789462631 . rs792673784 112016 rs7878 rs702742460 671066 rs7873 . . . . rs792903289 rs790316738 rs788203651 rs711263056 rs787072607 rs792209822 . rs786259474 166360 rs7902 596306 rs7868 rs792175322 571338 rs7925 rs791410765 rs789507914 rs787640429 rs789636832 . rs792886975 609520 rs7880 054834 rs7917 428187 rs7868 rs792266996 rs786388844 007180 rs7936 900032 rs7919 . 613519 rs7891 rs791754582 rs789398984 988211 rs7934 rs789096332 874865 rs7892 rs789587549 rs789410528 984886 rs7901 384397 rs7864 006470 rs7921 rs786857248 rs791440978 rs791402252 rs793461800 . 850525 rs7136 rs786872240 rs711012884 611333 rs7918 rs791670677 rs787657392 197019 rs7930 rs787692642 rs791979606 . rs788174140

2 4 2 2 2 2 2 2 2 5 2 4 2 2 2 2 2 2 2 2 4 2 2 2 2 4 3 2 3 4 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2

AG.CT AC.GT AC.GT AAC.GTT AAAAC.GTTTT AT.AT AG.CT AAAG.CTTT AC.GT AAC.GTT AAAT.ATTT AAC.GTT AAC.GTT AC.GT AAAAC.GTTTT AAC.GTT AG.CT AAAAAC.GTTTTT AT.AT AC.GT AAG.CTT AAG.CTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAT.ATTT AATC.GATT AAAG.CTTT AAAAC.GTTTT AC.GT AAAC.GTTT ACAG.CTGT AG.CT AC.GT AAC.GTT AATG.CATT AG.CT AAAT.ATTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AAAAC.GTTTT AC.GT AAAAC.GTTTT AAAC.GTTT AT.AT AC.GT AC.GT AG.CT AT.AT AC.GT AG.CT AAC.GTT AAAAC.GTTTT AT.AT AAAC.GTTT AG.CT AT.AT AAAAG.CTTTT AT.AT AAAC.GTTT AAAT.ATTT ACAT.ATGT AAC.GTT AG.CT AAAAAT.ATTTTT AAAC.GTTT AT.AT AT.AT AC.GT AC.GT AAAG.CTTT AAAT.ATTT AAAC.GTTT AT.AT AC.GT AAT.ATT AAAAG.CTTTT AT.AT AT.AT AAAAC.GTTTT AAT.ATT AC.GT

1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

262617368 262713548 263326543 263364936 263846716 263963666 264132460 264205318 264309440 264328482 264700907 264737354 264973757 265001384 265003129 265192041 265235969 265307146 265352792 265392411 265399580 265405209 265418912 265435029 265486462 265586830 266026484 266234926 266383443 266435026 266677477 266876858 266962429 267235082 267261615 267310940 267402394 267405219 267591764 267591764 267591764 267632306 267632306 267691007 267918577 268067250 268075050 268077804 268174386 268214730 268223127 268284288 268315441 268383105 268388170 268444287 269309624 269838617 270006928 270248909 270542615 270574196 270742806 270831601 270983569 270991754 271021687 271180161 271357851 271401980 271439660 271498404 271651716 271835521 271878992 271953083 272174674 272233128 272292274 272746581 272758026 272996971 273024467 273061239

262617381 262713559 263326552 263364953 263846745 263963677 264132470 264205339 264309450 264328506 264700928 264737368 264973782 265001394 265003144 265192053 265235981 265307166 265352813 265392435 265399592 265405233 265418931 265435043 265486479 265586851 266026495 266234938 266383457 266435042 266677503 266876879 266962440 267235098 267261631 267310972 267402404 267405250 267591789 267591789 267591789 267632328 267632328 267691023 267918599 268067264 268075062 268077814 268174396 268214740 268223138 268284307 268315450 268383118 268388193 268444313 269309646 269838630 270006938 270248930 270542626 270574223 270742827 270831628 270983582 270991763 271021712 271180183 271357869 271401992 271439671 271498417 271651730 271835542 271879012 271953115 272174689 272233139 272292290 272746591 272758043 272996986 273024488 273061248

7 6 5 6 6 6 5.5 5.5 5.5 8.33333 5.5 5 8.66667 5.5 3.2 4.33333 6.5 3.5 11 12.5 4.33333 8.33333 5 3.75 4.5 5.5 3 3.25 3 8.5 6.75 5.5 6 8.5 5.66667 8.25 5.5 8 6.5 6.5 6.5 4.6 4.6 8.5 4.6 3.75 6.5 5.5 5.5 5.5 6 10 5 4.66667 4.8 13.5 5.75 7 5.5 4.4 6 7 5.5 7 4.66667 5 4.33333 5.75 9.5 6.5 6 7 3.75 5.5 5.25 16.5 8 4 3.4 5.5 9 3.2 7.33333 5

. . . . ENSSSCT00000005843 ENSSSCT00000005845 ENSSSCT00000005854 . . . ENSSSCT00000005877 . . . . ENSSSCT00000005883 ENSSSCT00000005883 . . . . . . . ENSSSCT00000005884 ENSSSCT00000005884 . ENSSSCT00000005889 ENSSSCT00000005892 ENSSSCT00000005892 . . . . ENSSSCT00000027712 ENSSSCT00000027712 ENSSSCT00000005904 ENSSSCT00000005904 ENSSSCT00000005906 ENSSSCT00000027470 ENSSSCT00000005906 ENSSSCT00000005906 ENSSSCT00000027470 ENSSSCT00000005908 . ENSSSCT00000005913 ENSSSCT00000005913 ENSSSCT00000005913 . ENSSSCT00000005916 . ENSSSCT00000025444 ENSSSCT00000025444 ENSSSCT00000005917 ENSSSCT00000005917 ENSSSCT00000005917 . ENSSSCT00000005925 . ENSSSCT00000005931 ENSSSCT00000005933 ENSSSCT00000005934 . . . . . . . . . ENSSSCT00000005936 . . ENSSSCT00000005943 ENSSSCT00000005943 . . . . . . . .

. . . . UNC13B . TPM2 . . . RECK . . . . MELK MELK . . . . . . . PAX5 PAX5 . . FRMPD1 FRMPD1 . . . . CCDC180 CCDC180 TDRD7 TDRD7 NCBP1 TMOD1 NCBP1 NCBP1 TMOD1 XPA . NANS NANS NANS . TBC1D2 . . . . . . . NOR-1 . INVS MSANTD3 . . . . . . . . . . . . . GRIN3A GRIN3A . . . . . . . .

intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intron intron intron intergenic intergenic intergenic intergenic intron intron intron intron cds intron intron intron intron intron intergenic intron intron intron intergenic intron intergenic intron intron intron intron intron intergenic intron intergenic intron intron promoter intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

. 0.239 0.163 . 0.233 . 0.475 . -0.066 . 0.302 . -0.035 . 0.155 0.152 . 0.221 0.168 -0.324 0.227 0.644 0.956 0.075 . 0.13 . . 0.053 1.516 -0.007 0.351 -0.059 -0.141 . -0.081 0.021 0.137 3.377 3.377 3.377 -0.113 -0.113 . . . . 0.126 -0.243 -0.183 0.154 0.021 -0.199 0.157 0.061 0.355 -0.136 2.63 0.131 . . 0.31 -0.228 0.016 . 0.135 . 0.061 0.823 . 0.016 -0.027 0.007 . 0.192 0.157 0.078 0.607 0.044 . . -0.145 0.169 .

855894 rs7909 . rs793751484 rs793742188 rs787910726 rs791555299 rs793794750 rs792390355 011413 rs7881 rs786917869 rs787193157 . rs787315253 rs786232991 900363 rs7909 rs788533262 rs790142761 rs788128816 rs790715294 . rs787448143 . rs790025999 rs788067110 rs788991063 rs787423838 . rs793669994 rs790531402 rs792541181 rs787440082 rs792698595 rs793372049 rs786939698 rs791532007 406422 rs7929 rs787468622 . rs793548265 rs793548265 rs793548265 rs792019976 rs792019976 rs788452866 . 675527 rs7881 rs792571617 493746 rs7934 rs793646951 rs788208773 694296 rs7881 . . rs788512954 . rs790663100 693562 rs7927 rs790788355 rs790203602 rs788083919 rs788433485 . 299017 rs7927 rs787611906 rs789231471 . rs790976326 rs789856446 rs786495799 rs788845460 . 004455 rs7934 rs790009438 856295 rs7896 rs792118443 rs790922929 503970 rs7884 . rs789093622 rs788850838 . rs790174932 rs791537208 .

2 3 2 2 2 3 2 3 4 2 2 2 3 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 3 2 2 2 4 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 3 2 3 2 2 2 2 3 2 3 2 3 2 2 2 2 2 7 2 2 2 2 2 2 2 4

AAAAC.GTTTT AAC.GTT AT.AT AAAC.GTTT AT.AT AT.AT AC.GT AAC.GTT AAC.GTT AAT.ATT AAAAC.GTTTT AAAT.ATTT AT.AT AAT.ATT AAT.ATT AAT.ATT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AGAT.ATCT AAAC.GTTT AT.AT AT.AT AAAC.GTTT AAAC.GTTT AC.GT AAC.GTT AATG.CATT AT.AT AT.AT AAAT.ATTT AC.GT AG.CT AT.AT ACAT.ATGT AAAT.ATTT AAT.ATT AAAC.GTTT AG.CT AAG.CTT AC.GT AAT.ATT AT.AT AC.GT AG.CT AAAG.CTTT AAAT.ATTT AAAT.ATTT AAAAG.CTTTT AAAC.GTTT ATC.GAT AAAT.ATTT AAAAAT.ATTTTT AATT.AATT AATT.AATT ACCT.AGGT AATG.CATT AAAC.GTTT AAT.ATT AG.CT AAC.GTT AAAG.CTTT AAG.CTT AAT.ATT AAAC.GTTT AT.AT AAAC.GTTT AAAC.GTTT AT.AT AAAT.ATTT AT.AT AAAC.GTTT AC.GT AAC.GTT AAT.ATT AT.AT AT.AT AAAG.CTTT AAAT.ATTT AAC.GTT AC.GT AAC.GTT AAAC.GTTT

1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

273085229 273289902 273616322 273625203 273673546 273680718 274669091 274702357 275762746 275883692 275918634 275934031 276122793 276228672 276228672 276228672 276343188 276343188 276343188 276343188 276921343 277209481 278345247 278652579 278696633 278721639 278736955 278919031 278981242 279115732 279169476 279308067 279316784 279373943 279530627 279999791 280010475 280096310 280216619 280293377 280319828 280323233 280774865 281393587 281423614 281829450 281879360 282041284 282081817 282103096 282166986 282326357 282411724 282421330 282488774 282488774 282567854 282577821 282891846 282954869 283090760 283092347 283178294 283223732 283289688 283363874 283461861 283464372 283477321 283733410 283869449 283882974 283899942 284342716 284360126 284404144 284474631 284517141 284570995 284891476 284963048 285069130 285487791 285558479

273085245 273289913 273616336 273625221 273673559 273680729 274669115 274702372 275762759 275883717 275918653 275934064 276122803 276228685 276228685 276228685 276343204 276343204 276343204 276343204 276921372 277209508 278345257 278652589 278696655 278721656 278736969 278919047 278981262 279115748 279169486 279308094 279316797 279373956 279530639 279999816 280010512 280096323 280216642 280293394 280319845 280323243 280774878 281393598 281423628 281829459 281879388 282041300 282081846 282103116 282167000 282326371 282411746 282421347 282488804 282488804 282567866 282577862 282891860 282954887 283090773 283092360 283178316 283223750 283289702 283363897 283461871 283464388 283477334 283733431 283869471 283882987 283899961 284342742 284360145 284404163 284474640 284517153 284571009 284891496 284963076 285069139 285487802 285558497

3.4 4 7.5 4.75 7 6 12.5 5.33333 4.66667 8.66667 4 8.5 5.5 4.66667 4.66667 4.66667 4.25 4.25 4.25 4.25 7.5 7 5.5 5.5 5.75 4.5 7.5 5.66667 5.25 8.5 5.5 7 7 7 6.5 6.5 9.5 4.66667 6 9 6 5.5 4.66667 6 7.5 5 7.25 4.25 7.5 4.2 3.75 5 5.75 3 7.75 7.75 3.25 10.5 3.75 6.33333 7 4.66667 5.75 6.33333 5 6 5.5 4.25 3.5 11 5.75 7 5 13.5 6.66667 6.66667 5 6.5 3.75 5.25 9.66667 5 4 4.75

. . . . . . . . ENSSSCT00000005966 . . . . ENSSSCT00000034909 ENSSSCT00000033541 ENSSSCT00000033835 ENSSSCT00000034909 ENSSSCT00000005968 ENSSSCT00000033541 ENSSSCT00000033835 . . . . . . . ENSSSCT00000005980 . . . . . . . . . . . . . . ENSSSCT00000005990 . . . . ENSSSCT00000005998 . . ENSSSCT00000006000 . . . ENSSSCT00000025482 ENSSSCT00000006001 . . . . ENSSSCT00000006004 ENSSSCT00000006004 ENSSSCT00000028358 ENSSSCT00000006005 . . ENSSSCT00000024726 ENSSSCT00000024726 ENSSSCT00000024726 ENSSSCT00000006011 . . . ENSSSCT00000006017 . . . . . ENSSSCT00000006026 ENSSSCT00000006026 . . .

. . . . . . . . . . . . . SLC44A1 SLC44A1 SLC44A1 SLC44A1 SLC44A1 SLC44A1 SLC44A1 . . . . . . . RAD23B . . . . . . . . . . . . . . EPB41L4B . . . . TXN . . SVEP1 . . . MUSK MUSK . . . . KIAA0368 KIAA0368 PTGR1 DNAJC25 . . UGCG UGCG UGCG SUSD1 . . . SNX30 . . . . . . . . . .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intron intergenic intergenic intron intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intron intron promoter intron intergenic intergenic intron intron 3'utr intron intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic

. . 0.072 -0.223 -0.048 0.086 0.278 . 0.048 0.381 0.167 0.147 0.099 0.188 0.188 0.188 0.071 0.071 0.071 0.071 0.249 0.083 0.096 0.116 0.349 -0.051 0.35 . 0.124 . -0.083 . 0.119 -0.01 0.075 0.553 0.221 0.097 -0.002 -0.056 0.144 -0.009 . . 0.333 0.121 0.202 . 0.072 0.027 -0.012 0.231 . . . . 0.208 0.057 0.013 0.306 1.526 . . 0.202 0.295 . 0.236 0.325 1.93 0.248 . 0.35 . 0.054 -0.018 . 0.19 0.167 0.174 -0.064 0.088 -0.655 0.262 0.311

rs791563778 rs793754918 rs787501189 rs793874584 rs786591841 rs788371582 rs786270839 rs696427781 rs787056651 rs787438476 rs786940753 rs793853871 683203 rs7869 rs786637055 rs786637055 rs786637055 rs793358438 rs793358438 rs793358438 rs793358438 871417 rs7888 rs792208659 rs787439489 rs790065614 404650 rs7933 879079 rs7881 rs786495878 rs791349395 rs791643113 rs789305394 . rs789897842 rs787084421 045498 rs7924 . rs786621692 rs790768977 rs790737867 rs791761796 . rs793810552 . rs789057314 rs790322732 . rs792685861 253050 rs7899 098121 rs7927 rs793717781 364056 rs7925 rs789545329 280614 rs7901 rs710638899 806559 rs7883 rs790848194 rs790848194 . 304598 rs7895 rs792713268 rs787482397 519986 rs7898 rs793404741 036130 rs7926 rs789806971 . rs792781549 rs786291314 862195 rs7874 rs787158087 rs788429302 575160 rs7935 930035 rs7919 rs789052328 rs789017796 812570 rs7888 rs792705242 . rs792495533 288560 rs7898 rs792882540 rs787802400 . rs791873223 779104 rs7902

2 2 2 2 4 2 2 3 3 2 2 2 2 2 2 2 2 2 2 2 4 4 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 4 2 2 2 2 3 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 3 2 2

AAAT.ATTT AC.GT AT.AT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAC.GTT AAC.GTT AAC.GTT AAAC.GTTT AG.CT AAC.GTT AG.CT AC.GT ACAT.ATGT AT.AT AAGG.CCTT AG.CT AC.GT AAAC.GTTT AC.GT AT.AT AAAAG.CTTTT AT.AT ACGC.GCGT AAAC.GTTT AC.GT ACAC.GTGT AC.GT AG.CT AG.CT AAG.CTT AC.GT ATC.GAT AC.GT AC.GT AAAC.GTTT AAC.GTT AT.AT AAC.GTT AT.AT AC.GT AAAC.GTTT AC.GT AC.GT AAAAC.GTTTT AG.CT AT.AT AC.GT AG.CT AAAC.GTTT AAAAAC.GTTTTT AC.GT AAAAC.GTTTT AGG.CCT AAAC.GTTT AT.AT AC.GT AG.CT AATC.GATT AG.CT AGG.CCT AATG.CATT AGG.CCT AT.AT AG.CT AATG.CATT AG.CT AG.CT AAAC.GTTT AT.AT AT.AT AAAT.ATTT AC.GT AAAAC.GTTTT AAT.ATT AC.GT AAAAT.ATTTT AT.AT AG.CT AT.AT AT.AT ACAGGC.GCCTG AG.CT

1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

285580537 285670647 286276872 286288627 286326333 286519198 286807205 286807205 286807205 286923768 287135699 287171776 287189685 287221589 287461760 287509281 287698199 287711404 287730480 287795870 288029383 288148049 288494238 288530434 288688171 288688537 288760297 288807693 288947099 289224476 289368182 289500062 289555814 289556037 289625280 289755390 289758880 289865782 289903713 289919959 290032652 290277736 290497811 290530984 290677590 290728920 291071081 291125695 291134333 291197612 291251807 291298850 291669887 291677942 291690642 291718521 291898230 291967518 291978400 291984413 291993539 292010135 292190872 292677756 292761509 292777473 292838423 292846040 292864642 292953275 293041864 293041864 293337997 293339779 293392809 293488217 293759147 294783616 294802876 295356903 295500128 295601010 296004340 296231881

285580559 285670659 286276881 286288639 286326348 286519221 286807229 286807229 286807229 286923782 287135712 287171795 287189721 287221601 287461779 287509292 287698212 287711413 287730492 287795890 288029392 288148058 288494262 288530457 288688182 288688563 288760307 288807734 288947112 289224488 289368191 289500078 289555836 289556055 289625293 289755409 289758898 289865796 289903723 289919977 290032663 290277747 290497825 290531009 290677605 290728953 291071104 291125705 291134344 291197623 291251825 291298877 291669900 291677968 291690658 291718561 291898244 291967530 291978412 291984440 291993551 292010165 292190900 292677767 292761521 292777487 292838455 292846049 292864652 292953295 293041875 293041875 293338011 293339792 293392828 293488233 293759164 294783635 294802889 295356915 295500144 295601021 296004359 296231893

5.75 6.5 5 3.25 4 6 8.33333 8.33333 8.33333 3.75 7 6.66667 18.5 6.5 5 6 3.5 5 6.5 5.25 5 5 5 12 3 6.75 5.5 10.5 7 6.5 5 5.66667 11.5 6.33333 7 10 4.75 5 5.5 6.33333 6 6 3.75 13 8 6.8 12 5.5 6 6 4.75 4.66667 7 5.4 5.66667 10.25 7.5 6.5 6.5 7 6.5 10.3333 7.25 4 6.5 7.5 8.25 5 5.5 5.25 6 6 3.75 7 4 5.66667 9 4 7 6.5 8.5 6 3.33333 6.5

. ENSSSCT00000006030 . . . . ENSSSCT00000023943 ENSSSCT00000006041 ENSSSCT00000032138 . . . . . . . . . . . ENSSSCT00000006045 . . ENSSSCT00000006050 ENSSSCT00000006050 ENSSSCT00000006050 ENSSSCT00000006050 ENSSSCT00000006050 . ENSSSCT00000023014 ENSSSCT00000023014 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000025473 ENSSSCT00000006055 ENSSSCT00000006055 . . . ENSSSCT00000006057 ENSSSCT00000023007 ENSSSCT00000006061 . . . ENSSSCT00000006064 . . . . . . . .

. ZNF618 . . . . . . . . . . . . . . . . . . PAPPA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . MEGF9 MEGF9 . . . . . . . . . RAB14 . . . . . . . .

intergenic intron intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intron intron intron intron intron intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

-0.284 -0.003 0.092 . 0.809 0.159 . . . . 0.303 0.285 0.245 -0.177 -0.253 -0.157 0.038 -0.013 . . -0.02 . . -0.167 . . 0.001 0.099 0.153 -0.273 0.066 -0.235 -0.098 -0.121 0.271 0.599 0.044 . -0.189 0.662 -0.212 -0.171 0.295 . 0.274 . . -0.051 . -0.052 -0.146 . -0.031 0.076 0.095 -0.093 . 0.022 -0.061 -0.091 1.286 . -0.235 -0.293 0.353 0.081 0.021 -0.048 . 0.152 0.095 0.095 0.085 0.289 -0.02 1.56 -0.149 . . . . . . .

585862 rs7912 rs791785667 rs791057608 685712 rs7928 051780 rs7874 rs792932811 684868 rs7866 684868 rs7866 684868 rs7866 rs792050705 rs792386815 rs792353633 803416 rs7921 013579 rs7900 rs788480697 rs694102459 . . rs789526364 rs788440889 . rs786610255 812169 rs7891 512343 rs7883 749062 rs6976 . rs790746535 rs793220131 rs710188634 rs788950590 516996 rs7868 440133 rs7905 rs788481234 rs786703233 rs786812479 rs790469535 rs789446321 rs788026427 655432 rs7937 102767 rs7882 653670 rs7888 rs791923935 rs787120072 . rs791323491 rs790543834 rs793229422 rs789983271 . rs787666624 377804 rs7887 541807 rs7892 . 920638 rs7926 970044 rs7910 645386 rs7933 rs787185369 rs787632424 rs787155767 598359 rs7908 rs790537206 rs790249687 rs791571219 rs788712895 155830 rs7896 321603 rs7920 rs697109109 . . rs787821196 239028 rs7894 239028 rs7894 rs790124314 rs793780291 . 458347 rs7920 rs792204132 466385 rs7877 152872 rs7929 rs791801771 . . rs711021477 rs787907250

2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 4 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 3 2 5 6 2 4 2 2 2 2 2 2 2 3 3 2 2 2 3 2 2 2 3 2 2 2 2 2 2 2 3 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2

AG.CT AG.CT AAC.GTT AC.GT AAAC.GTTT AAAC.GTTT AG.CT AAAAC.GTTTT AT.AT AAAG.CTTT AG.CT AC.GT AAC.GTT AAAC.GTTT AGG.CCT AAT.ATT AAAC.GTTT AAAC.GTTT AC.GT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AAAAC.GTTTT AC.GT AAAT.ATTT AC.GT AAC.GTT AC.GT AC.GT AC.GT AAAAC.GTTTT AAAAAC.GTTTTT AAAAAG.CTTTTT AAAT.ATTT AT.AT AC.GT AC.GT AAAAC.GTTTT AAAC.GTTT AG.CT AAC.GTT AT.AT ATCC.GGAT AC.GT AAAAT.ATTTT AAGG.CCTT AAAT.ATTT AAACC.GGTTT AAC.GTT AC.GT AG.CT AAAC.GTTT AC.GT AAAT.ATTT AAAC.GTTT ACAG.CTGT AAAT.ATTT AT.AT AG.CT ATCC.GGAT AC.GT AGG.CCT AAAT.ATTT AAAT.ATTT AAAT.ATTT AG.CT AAC.GTT AAAAC.GTTTT AG.CT AC.GT AAAAAG.CTTTTT AC.GT AG.CT AAAAC.GTTTT AAC.GTT AAAT.ATTT AG.CT AGAT.ATCT AAAT.ATTT AAAC.GTTT AC.GT AAAC.GTTT AAAG.CTTT AAT.ATT

1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

296306983 296745361 296765741 296808879 296844296 297147722 297181655 297224903 297443813 297473997 297579969 297604061 297724275 297734558 298064435 298417588 298643920 299018728 299069742 299082218 299338165 299377781 299377781 299448983 299664011 299734059 299755357 299824668 299827524 299889118 299892976 299944209 300171334 300178057 300341631 300363853 300388316 300808794 300827048 300873670 300901071 301017333 301185432 301197891 301291059 301294104 301380062 301691448 301822455 302064138 302391661 302724749 302810153 303185103 303448136 303622789 304007127 304252498 304508171 304569547 304577406 304622235 304990828 304990828 305442780 306192405 306224057 306299923 306571573 307007849 307280607 308233598 309977506 310072676 310137370 310139339 310833055 310847880 310858723 311076812 311142963 311336146 311897732 311929960

296306993 296745371 296765761 296808906 296844313 297147740 297181678 297224917 297443824 297474021 297579991 297604071 297724294 297734571 298064451 298417600 298643932 299018747 299069770 299082244 299338179 299377801 299377801 299448993 299664036 299734070 299755369 299824681 299827545 299889132 299892996 299944233 300171354 300178074 300341642 300363869 300388325 300808812 300827063 300873686 300901087 301017344 301185452 301197909 301291087 301294133 301380076 301691474 301822471 302064148 302391672 302724766 302810163 303185122 303448153 303622806 304007145 304252510 304508187 304569588 304577440 304622249 304990845 304990845 305442805 306192423 306224069 306299944 306571600 307007860 307280625 308233607 309977520 310072697 310137387 310139356 310833067 310847891 310858749 311076842 311142977 311336174 311897744 311929988

5.5 5.5 7 14 4.5 4.75 12 3 6 6.25 11.5 5.5 6.66667 3.5 5.66667 4.33333 3.25 5 14.5 6.75 3.75 4.2 4.2 5.5 6.5 6 4.33333 7 11 7.5 4.2 4.16667 3.5 4.5 6 8.5 5 3.8 4 8.5 5.66667 6 5.25 9.5 5.8 7.5 3.75 5.4 5.66667 5.5 6 4.5 5.5 5 4.5 4.5 4.75 6.5 8.5 10.5 17.5 5 4.5 4.5 6.5 9.5 4.33333 4.4 14 6 3.16667 5 7.5 4.4 6 4.5 6.5 3 6.75 7.75 7.5 7.25 3.25 9.66667

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000006127 . promoter ENSSSCT00000023452 . promoter ENSSSCT00000023452 . intron ENSSSCT00000006135 STRBP intron ENSSSCT00000006135 STRBP intron . . intergenic . . intergenic . . intergenic ENSSSCT00000006139 DENND1A intron . . intergenic . . intergenic . . intergenic ENSSSCT00000006145 NR6A1 intron ENSSSCT00000029437 NR6A1 intron ENSSSCT00000033935 NR6A1 intron ENSSSCT00000029437 NR6A1 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000006159 HSPA5 intron ENSSSCT00000006160 GAPVD1 intron ENSSSCT00000006160 GAPVD1 intron ENSSSCT00000006160 GAPVD1 intron ENSSSCT00000006160 GAPVD1 intron ENSSSCT00000006160 GAPVD1 intron ENSSSCT00000027058 . intron ENSSSCT00000027058 . promoter ENSSSCT00000006162 PBX3 intron ENSSSCT00000006162 PBX3 intron ENSSSCT00000006162 PBX3 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000006168 . intron ENSSSCT00000006177 STXBP1 intron . . intergenic . . intergenic ENSSSCT00000006207 . intron ENSSSCT00000006225 C9orf114 promoter . . intergenic . . intergenic ENSSSCT00000006256 FNBP1 intron . . intergenic ENSSSCT00000006270 ASS1 intron . . intergenic ENSSSCT00000006271 FUBP3 intron ENSSSCT00000006271 FUBP3 intron ENSSSCT00000006279 LAMC3 intron ENSSSCT00000006282 LAMC3 intron ENSSSCT00000006286 POMT1 intron ENSSSCT00000006294 SETX intron ENSSSCT00000006294 SETX intron . . intergenic . . intergenic ENSSSCT00000022734 ADAMTS13 intron ENSSSCT00000006315 VAV2 intron . . intergenic . . intergenic ENSSSCT00000006349 RBFA intron ENSSSCT00000006353 TXNL4A intron ENSSSCT00000006353 TXNL4A intron . . intergenic . . intergenic . . intergenic ENSSSCT00000006357 TARSL2 3'utr . . intergenic ENSSSCT00000029763 . promoter . . intergenic . . intergenic

. . . . . . . 0.21 0.114 0.172 0.318 0.27 . . -0.031 . 0.092 . 0.232 . 0.486 0.459 0.459 0.349 -0.054 0.25 4.587 -0.069 0.042 0.368 0.145 0.122 0.121 0.232 0.252 2.358 0.216 0.162 1.472 . -0.5 -0.441 -0.228 0.439 0.261 -0.237 . 0.062 1.286 0.576 -0.008 . 0.281 . -0.344 -0.333 0.148 0.093 0.048 . 0.222 -0.633 . . -0.29 . 1.09 -0.262 1.652 1.68 0.019 -0.307 . . . . . . . 0.484 . . . .

rs790386439 . . 764711 rs7934 rs786528438 014732 rs7923 rs793402115 rs791630919 . rs787634728 . . rs792626000 rs790101678 . rs789979951 rs792727121 090514 rs7927 . . 589655 rs7904 rs791455385 rs791455385 rs793150925 rs788479754 rs793648857 111438 rs7876 rs792877127 rs705994651 rs791340267 rs791521330 rs791040032 rs786869189 rs786859504 787970 rs7925 491117 rs7877 582310 rs7876 376713 rs7867 369055 rs7865 rs791464182 . rs790576264 rs787745189 rs788722446 rs789161390 . rs793314843 rs789195748 rs791456528 rs788473073 . rs792959720 rs789003993 rs789065348 rs793282743 rs793193415 rs790913661 rs788245287 . 484992 rs7938 rs789082484 rs791878078 rs791500988 rs791500988 rs786331726 rs786801295 rs793595646 487055 rs7889 540137 rs7906 rs787239809 rs786570512 . rs786517412 rs793227167 rs792914287 rs791733339 rs789655674 rs792442818 rs790857695 rs695509989 rs788713628 907273 rs7929 rs789177870 rs792376082

3 3 2 2 4 2 3 2 3 2 3 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 4 4 4 2 2 3 2 2 2 2 3 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 3 3 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2

AC.GT AC.GT AAAAT.ATTTT AAAT.ATTT AC.GT AT.AT AAT.ATT AG.CT AT.AT AC.GT AAC.GTT AG.CT AAAAC.GTTTT AG.CT AAAT.ATTT AAAC.GTTT AAAAC.GTTTT AAAC.GTTT AAAG.CTTT AC.GT AC.GT AC.GT AAAAC.GTTTT ACAT.ATGT AAAT.ATTT AAC.GTT AAAC.GTTT AT.AT AAAT.ATTT AT.AT AT.AT AAAAAG.CTTTTT AAAC.GTTT AG.CT AG.CT AAAC.GTTT AAG.CTT AAC.GTT AC.GT AAAT.ATTT AAAC.GTTT AAGG.CCTT AAC.GTT AT.AT AAAC.GTTT AT.AT AAAC.GTTT AC.GT AG.CT ACT.AGT AGG.CCT AC.GT ACAT.ATGT AAAC.GTTT AC.GT AC.GT AT.AT AAAC.GTTT AAC.GTT ACAT.ATGT AAC.GTT AAG.CTT AG.CT AC.GT AAAAC.GTTTT AAC.GTT AC.GT AG.CT AGG.CCT AAAC.GTTT AT.AT AAC.GTT AATC.GATT AAAC.GTTT AC.GT AG.CT AAC.GTT AATG.CATT AAAC.GTTT AAAAC.GTTTT AC.GT AAAAT.ATTTT AAAAC.GTTTT AC.GT

1 1 1 1 1 1 1 1 1 1 1 1 1 1 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10

312205548 312264615 312300085 312333791 312357739 312361685 312607522 312826748 313147182 313505206 314849237 315205481 315209256 315314217 45277 51881 74596 183123 208539 518496 579486 861830 862125 876903 879528 926935 1096889 1675392 1701587 1721260 2091846 2158501 2311719 2401047 2487658 2690250 2783087 2827044 3276260 3551073 3773778 3830249 3950750 4026232 4184355 4257892 4362296 4911952 4929648 4933803 4933852 5108443 5132219 5181949 5204906 5410462 5838717 5868245 5874152 6012990 6035977 6051977 6282297 6388369 7032655 7033545 7118711 7145045 7178559 7263139 7278949 7300614 7320196 7593401 7878020 7888261 8012796 8199005 8317091 8407285 8465879 8577080 8652363 8783517

312205562 312264635 312300103 312333808 312357750 312361696 312607535 312826758 313147192 313505224 314849248 315205500 315209277 315314240 45300 51903 74618 183135 208557 518526 579496 861843 862144 876914 879552 926950 1096907 1675405 1701603 1721283 2091858 2158534 2311730 2401059 2487670 2690272 2783101 2827057 3276282 3551096 3773795 3830277 3950768 4026241 4184369 4257906 4362308 4911966 4929659 4933819 4933871 5108456 5132237 5181970 5204931 5410474 5838726 5868260 5874171 6013009 6035993 6051989 6282331 6388379 7032673 7033561 7118720 7145059 7178572 7263161 7278966 7300628 7320207 7593416 7878032 7888275 8012819 8199032 8317109 8407300 8465890 8577103 8652387 8783528

7.5 10.5 3.8 4.5 6 6 4.66667 5.5 5.5 9.5 4 10 4.4 12 6 5.75 4.6 3.25 4.75 15.5 5.5 7 4 3 6.25 5.33333 4.75 7 4.25 12 6.5 5.66667 3 6.5 6.5 5.75 5 4.66667 11.5 6 4.5 7.25 6.33333 5 3.75 7.5 3.25 7.5 6 5.66667 6.66667 7 4.75 5.5 13 6.5 5 4 6.66667 5 5.66667 4.33333 17.5 5.5 3.8 5.66667 5 7.5 4.66667 5.75 9 5 3 4 6.5 7.5 8 7 4.75 3.2 6 4.8 5 6

ENSSSCT00000006371 OR10AG1 promoter ENSSSCT00000006373 . cds . . intergenic . . intergenic ENSSSCT00000006377 . promoter . . intergenic . . intergenic . . intergenic ENSSSCT00000006399 . promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011811 NDUFAB1 intron ENSSSCT00000011812 UBFD1 3'utr ENSSSCT00000011815 COG7 intron ENSSSCT00000011815 COG7 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011818 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011825 BRINP3 intron ENSSSCT00000011825 BRINP3 intron ENSSSCT00000011825 BRINP3 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011830 ESRRG intron ENSSSCT00000011830 ESRRG intron

. . . . -0.074 . . . . . . . . . . 0.098 4.025 . . . . . . 0.004 . -0.153 . 0.051 -0.233 -0.086 . 0.169 0.116 0.259 . -0.158 . -0.141 -0.222 -0.057 . 0.06 -0.328 0.166 0.086 . . . 0.327 -0.167 -0.207 -0.107 0 0.335 -0.162 -0.099 -0.207 -0.081 -0.139 -0.136 -0.079 0.223 -0.107 -0.175 -0.088 -0.192 . 0.036 -0.125 -0.009 . -0.185 -0.163 . 0.297 0.043 . -0.049 -0.238 . . -0.146 0.125 0.063

rs791844213 459435 rs7931 . rs699408104 rs793230177 708862 rs7895 rs790484225 . rs790166632 rs789508903 812056 rs7900 543382 rs7907 rs786282086 . rs792373976 rs791455171 rs786218814 rs786755422 rs789022093 144473 rs7891 rs786886041 . 217621 rs7911 . rs791031652 rs791386715 910257 rs7928 rs788357198 rs789265533 . rs790664076 rs787548172 rs790076880 . rs787028695 rs789099648 rs792532332 rs790105288 rs788196815 686692 rs6958 rs790238737 . rs786477753 rs789575508 rs786741293 rs793079454 rs787121554 rs790773764 rs789468717 . . 202663 rs7869 rs793420717 906470 rs7931 rs787420647 350471 rs7892 . 329724 rs7920 rs791540704 . 102995 rs7928 515745 rs7888 340880 rs7874 rs787569450 rs791859959 . . 050539 rs7913 667829 rs7095 rs792531132 . rs791188810 rs790170023 rs790557827 rs792715015 rs790813199 203712 rs7909 652233 rs7908 rs790050469 197562 rs7890 . rs791053155 rs790156236 rs787869528

2 2 2 2 2 2 2 4 2 3 3 2 2 3 2 2 2 2 2 4 4 2 3 3 2 2 2 4 2 4 2 2 2 3 2 4 2 2 3 2 2 2 2 2 2 3 2 4 3 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 3 2 2 2 2 2 3 2 2 2 2 4 2 2 2 2 2 2 2

AAT.ATT AAAT.ATTT AC.GT AGAT.ATCT AT.AT AAGG.CCTT AG.CT AG.CT AT.AT AG.CT AAT.ATT ACC.GGT AATG.CATT AT.AT AT.AT AC.GT AG.CT AT.AT AAAG.CTTT AAAAC.GTTTT AG.CT AC.GT AAAAC.GTTTT AC.GT AAC.GTT AC.GT AAAC.GTTT AAAC.GTTT AAAC.GTTT AG.CT AAG.CTT AAC.GTT AC.GT AAC.GTT AAAAG.CTTTT AAAAC.GTTTT AAAT.ATTT AAAAC.GTTTT AC.GT AAAC.GTTT AAAAT.ATTTT AAAC.GTTT AGC.GCT AAAG.CTTT AC.GT AC.GT AG.CT AC.GT AAAC.GTTT AAAC.GTTT AC.GT AAAAC.GTTTT AT.AT AGAT.ATCT AAAT.ATTT AAAAT.ATTTT AATG.CATT AAAC.GTTT AAAC.GTTT AT.AT AAAT.ATTT AC.GT AAT.ATT AAC.GTT AAAAC.GTTTT AAAAT.ATTTT AAC.GTT AG.CT AAC.GTT AT.AT AAAT.ATTT AAAT.ATTT AAAC.GTTT AAAC.GTTT AAT.ATT AC.GT AAAC.GTTT AG.CT AAC.GTT AC.GT AAAC.GTTT AC.GT AC.GT AAAG.CTTT

10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10

8811335 8885213 8947357 9090155 9093616 9155413 9295064 9361545 9374394 9412632 9443807 9530761 9711455 9725585 9733545 9772882 9892614 9955964 10005953 10027488 10132674 10143409 10249604 10419206 10578024 10636105 10702368 10982823 11121634 11232724 11448812 11466193 11512468 11546640 11982895 12000598 12115803 12291980 12499149 12747432 12931770 13043059 13050995 13110005 13157205 13214057 13231867 13259906 13267265 13324777 13365961 13400645 13616368 13655956 13660845 14020510 14751923 14963667 14980771 14987802 15045968 15142079 15164865 15169584 15207380 15314950 15319411 15633769 15656879 15707441 15899251 15964402 16207111 16403436 16516611 16762421 16828804 16851009 16991445 17766994 17846363 17970243 18017369 18343206

8811349 8885232 8947369 9090176 9093637 9155426 9295076 9361554 9374406 9412642 9443823 9530785 9711481 9725594 9733555 9772902 9892627 9955988 10005969 10027504 10132684 10143425 10249625 10419217 10578040 10636115 10702382 10982841 11121653 11232734 11448825 11466204 11512480 11546658 11982916 12000613 12115821 12292002 12499180 12747446 12931792 13043073 13051008 13110020 13157215 13214071 13231878 13259917 13267292 13324797 13365975 13400669 13616379 13655969 13660859 14020538 14751941 14963693 14980793 14987813 15045990 15142090 15164881 15169598 15207404 15314967 15319424 15633783 15656895 15707451 15899265 15964426 16207125 16403450 16516630 16762461 16828826 16851022 16991458 17767004 17846377 17970256 18017379 18343224

5 5 6.5 5.5 11 3.5 6.5 5 6.5 5.5 5.66667 8.33333 6.75 5 5.5 10.5 7 12.5 4.25 3.4 5.5 8.5 4.4 6 5.66667 5.5 3.75 4.75 5 5.5 4.66667 4 6.5 6.33333 4.4 3.2 4.75 4.6 16 3.75 4.6 3.75 4.66667 4 5.5 7.5 6 6 7 5.25 7.5 5 6 3.5 3.75 5.8 4.75 6.75 5.75 6 5.75 6 5.66667 5 5 3.6 4.66667 7.5 5.66667 5.5 3.75 6.25 3.75 3.75 6.66667 20.5 5.75 7 4.66667 5.5 3.75 7 5.5 4.75

ENSSSCT00000011830 ESRRG intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000025633 GPATCH2 intron ENSSSCT00000025633 GPATCH2 intron ENSSSCT00000025633 GPATCH2 intron ENSSSCT00000025633 GPATCH2 intron ENSSSCT00000026746 SPATA17 intron ENSSSCT00000026746 SPATA17 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011833 TGFB2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011847 1-Mar intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011854 AIDA intron . . intergenic . . intergenic ENSSSCT00000011858 . intron . . intergenic ENSSSCT00000029068 ZNF596 intron . . intergenic . . intergenic ENSSSCT00000025010 DEGS1 intron ENSSSCT00000011871 WDR26 intron ENSSSCT00000011871 WDR26 intron ENSSSCT00000011871 WDR26 intron . . intergenic ENSSSCT00000027767 CNIH3 intron ENSSSCT00000027767 CNIH3 intron ENSSSCT00000024654 . intron ENSSSCT00000024654 . intron ENSSSCT00000029429 . intron ENSSSCT00000011880 SDE2 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000028613 ITPKB intron . . intergenic . . intergenic ENSSSCT00000011884 CDC42BPA intron ENSSSCT00000011891 PLD5 intron . . intergenic ENSSSCT00000011894 AKT3 intron ENSSSCT00000011894 AKT3 intron ENSSSCT00000028157 . intron

-0.026 -0.18 0.991 -0.118 0.249 -0.33 -0.342 -0.101 0.083 -0.2 0.042 0.069 0.652 -0.036 1.214 -0.225 0.146 -0.136 1.408 . -0.063 . . -0.281 0.688 -0.202 . -0.024 . 0.103 -0.053 0.009 0.248 -0.036 -0.13 0.213 . . -0.23 -0.165 -0.159 -0.109 . -0.009 -0.203 0.093 -0.081 -0.032 0.874 -0.008 . . 0.053 0.153 0.194 0.374 -0.113 0.159 . . -0.069 -0.265 0.314 0.049 0.036 0.015 0.142 0.275 . 0.201 0.014 . 0.025 . . -0.225 0.463 . 1.345 0.043 0.219 0.007 0.112 .

rs707590475 rs790819958 871854 rs7911 874061 rs7911 rs788783901 . rs786767916 . rs788304655 rs791458282 349376 rs7873 068934 rs7889 rs789479694 . rs793307899 rs786323567 rs792441139 . . rs792739626 . rs793105625 rs793627903 rs789976916 rs789938844 rs695037902 rs793265678 rs793031380 rs791078934 673643 rs7925 rs790299823 rs791721078 . rs791811106 rs792026381 . 820260 rs7864 rs789563382 rs789824821 945240 rs7892 rs790836235 rs787538384 rs789025652 042582 rs7928 . 399172 rs7929 . . 715607 rs7894 rs787490101 831426 rs6945 531210 rs7910 rs793846089 . rs786287104 799700 rs7874 rs786703479 rs793337367 rs793834344 084828 rs7901 081344 rs7885 840518 rs7873 rs789333623 194882 rs7926 rs692419319 rs712705666 rs787654037 . 916037 rs7909 rs789508405 530922 rs7905 843949 rs7886 . . rs793058454 rs788617966 rs790876086 . rs696314909 385695 rs7055 rs790619580 rs787597184 . 650219 rs7866

2 2 2 4 4 4 2 2 3 2 2 2 2 2 2 3 2 2 2 2 2 5 3 3 2 3 2 2 2 3 2 2 4 2 2 2 2 3 4 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 3 2 2 2 2 2 2 2 3 2 2 2 2 2 4 2 3 2 2 2 2

AC.GT AAAAC.GTTTT AC.GT AC.GT AAT.ATT AAGAG.CTCTT AAC.GTT AAAC.GTTT AAAT.ATTT AAAT.ATTT AAAAAT.ATTTTT AC.GT AAAC.GTTT AAAC.GTTT AAAG.CTTT AAAG.CTTT AAAG.CTTT AG.CT AAC.GTT AG.CT AG.CT AC.GT AG.CT AG.CT AAAC.GTTT AAC.GTT AG.CT ACAG.CTGT AT.AT AC.GT AC.GT AAAAT.ATTTT AT.AT AT.AT AAAAT.ATTTT AC.GT AC.GT AAAT.ATTT AAAT.ATTT AAGG.CCTT AAAG.CTTT AAATT.AATTT AC.GT AT.AT AAC.GTT AC.GT AAAAC.GTTTT ACCT.AGGT AGG.CCT AC.GT AG.CT AAAAG.CTTTT AAT.ATT AT.AT AC.GT AAAAAG.CTTTTT AAAC.GTTT AAAAC.GTTTT AAAT.ATTT AAAC.GTTT AAAAAC.GTTTTT AAAC.GTTT AAAG.CTTT AAAC.GTTT AC.GT AAT.ATT AAAC.GTTT AC.GT GGGGC.GCCCC AAAAC.GTTTT AAAAG.CTTTT AAC.GTT AAG.CTT AAAC.GTTT AT.AT AATGAT.ATCATT AC.GT AC.GT AAC.GTT AAC.GTT AG.CT AAAAC.GTTTT AT.AT AT.AT

10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10

19030750 19060492 19083231 19113272 19285308 19290095 19494059 19721761 19839670 20147358 20344443 20382343 20415968 20415968 20633614 20633614 20633614 20846287 21128379 21320237 21478014 21544872 21660657 21660657 21805698 21830700 22046115 22056932 22076577 23483977 23563738 23575950 23680614 23688141 24103504 24481188 24743814 24954372 25205779 25413041 25473766 25715672 25813640 25878822 25888851 25969868 26423656 26454479 26572109 26684828 26729457 26732812 26757359 26827090 26957983 27078634 27087987 27104376 27320475 27546613 27732636 27747018 27748502 27750930 28451562 28606450 28852543 29093010 29170931 29196193 29359330 29574906 29816101 29944023 30009603 30130645 30154518 30235194 30346780 30392044 30596947 30750516 30941517 31046603

19030775 19060514 19083262 19113284 19285328 19290127 19494079 19721795 19839682 20147377 20344461 20382354 20415987 20415987 20633629 20633629 20633629 20846308 21128391 21320248 21478026 21544884 21660668 21660668 21805716 21830719 22046128 22056947 22076597 23483989 23563748 23575965 23680627 23688151 24103521 24481198 24743825 24954388 25205811 25413074 25473780 25715708 25813652 25878834 25888868 25969884 26423679 26454493 26572120 26684849 26729470 26732829 26757372 26827100 26957994 27078651 27088001 27104393 27320497 27546628 27732658 27747040 27748520 27750944 28451578 28606464 28852561 29093038 29170951 29196210 29359348 29574920 29816112 29944041 30009615 30130674 30154542 30235205 30346793 30392055 30596962 30750530 30941535 31046612

13 4.6 16 6.5 7 6.6 7 8.75 3.25 5 3.16667 6 5 5 4 4 4 11 4.33333 6 6.5 6.5 6 6 4.75 6.66667 7 4 10.5 6.5 5.5 3.2 7 5.5 3.6 5.5 6 4.25 8.25 8.5 3.75 7.4 6.5 6.5 6 8.5 4.8 3.75 4 11 7 3.6 4.66667 5.5 6 3 3.75 3.6 5.75 4 3.83333 5.75 4.75 3.75 8.5 5 4.75 14.5 3.5 3.6 3.8 5 4 4.75 6.5 5 12.5 6 4.66667 4 8 3 9.5 5

. . . . . . . ENSSSCT00000011898 . . . . ENSSSCT00000011902 ENSSSCT00000026658 ENSSSCT00000011902 ENSSSCT00000026658 ENSSSCT00000022970 . . . ENSSSCT00000032587 ENSSSCT00000032587 ENSSSCT00000011908 ENSSSCT00000025284 . . ENSSSCT00000011910 . . . . . . . . ENSSSCT00000011919 . . . . . ENSSSCT00000011931 . . . . . . . . . . . . . . . . ENSSSCT00000026077 . . ENSSSCT00000030669 ENSSSCT00000030669 ENSSSCT00000030669 . ENSSSCT00000026899 ENSSSCT00000011955 ENSSSCT00000011958 . . ENSSSCT00000011960 ENSSSCT00000030381 . . ENSSSCT00000011969 ENSSSCT00000011969 ENSSSCT00000011969 . . ENSSSCT00000011974 . . . .

. . . . . . . DESI2 . . . . KIF26B KIF26B KIF26B KIF26B . . . . . . . . . . . . . . . . . . . TP53BP2 . . . . . NEK7 . . . . . . . . . . . . . . . . NR5A2 . . CAMSAP2 CAMSAP2 CAMSAP2 . IPO9 UBE2T SYT2 . . . CDC14B . . HSD17B3 HSD17B3 HSD17B3 . . ERCC6L2 . . . .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intron intron intron intron promoter intergenic intergenic intergenic intron intron intron intron intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic 3'utr intron intron intergenic intron intron intron intergenic intergenic intron intron intergenic intergenic intron intron intron intergenic intergenic intron intergenic intergenic intergenic intergenic

0.082 . . -0.33 0.658 0.012 -0.072 0.286 -0.125 0.005 -0.252 0.001 0.036 0.036 0.251 0.251 0.251 0.475 . . . . . . . 0.104 0.296 -0.16 0.037 . . 0.064 0.02 . -0.096 -0.466 0.286 . -0.007 0.399 0.006 . . 0.022 . 0.009 -0.078 -0.127 -0.208 -0.137 0.05 -0.163 -0.002 0.227 . . . 0.175 -0.174 0.318 0.006 1.108 3.734 -0.141 -0.28 0.116 1.786 -0.495 -0.284 . . . . . 0.166 0.111 -0.064 0.717 0.138 . -0.102 0.043 . .

. rs792851272 . rs787023993 . 266415 rs7899 rs791604414 rs789435300 . rs691945452 rs787630331 rs792471802 rs787097923 rs787097923 rs790802809 rs790802809 rs790802809 . rs790180302 rs791021197 rs789416626 . rs790051654 rs790051654 rs791237464 rs791240903 . . . rs789506852 . rs787339688 332796 rs7913 rs791323503 rs790065989 rs788311382 rs791515574 rs791153079 rs787858034 rs790980759 656464 rs7898 450971 rs7892 rs786834065 955283 rs7883 187122 rs7876 rs793233399 rs791824894 . rs790749820 597436 rs7905 948074 rs7906 rs792222761 189779 rs7884 rs787308746 rs790813389 rs786428495 rs787513680 . rs788467062 rs792056328 rs789571944 rs786717134 104251 rs7899 rs792312322 . rs791878670 rs786396032 rs791399731 974407 rs7922 rs788005751 rs793228739 052026 rs7874 . 173428 rs7879 rs791408508 . 270812 rs7865 rs792392932 rs790472787 rs792141902 rs792138543 . rs790881526 rs790445697

3 2 3 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 3 2 4 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 3 2 4 2 2 2 2 2 3 2

AAC.GTT AT.AT AG.CT AT.AT AAT.ATT AG.CT AC.GT AAAT.ATTT AC.GT AAAC.GTTT AAAC.GTTT AAC.GTT AC.GT AT.AT AT.AT AAAAT.ATTTT AAC.GTT AG.CT ACAT.ATGT AC.GT AC.GT AAAC.GTTT AAAG.CTTT AC.GT AAAC.GTTT AAAC.GTTT AAAC.GTTT AC.GT AT.AT AAAAT.ATTTT AAAAG.CTTTT AAT.ATT AAAC.GTTT ACC.GGT AAAG.CTTT AAAT.ATTT AG.CT AAAT.ATTT AAAT.ATTT AAAAC.GTTTT AAAAT.ATTTT AC.GT AATG.CATT AAG.CTT AAAAG.CTTTT AT.AT AAAAT.ATTTT AAAAAC.GTTTTT AG.CT AAAAC.GTTTT AC.GT AT.AT AC.GT AAAC.GTTT AT.AT AC.GT AC.GT AC.GT AAAC.GTTT AT.AT AAC.GTT AAAAAC.GTTTTT AAAAAC.GTTTTT AC.GT AC.GT AATC.GATT AAAT.ATTT AT.AT AAAC.GTTT AAAC.GTTT AAAC.GTTT AG.CT AC.GT AAAG.CTTT AT.AT AT.AT AGGG.CCCT AC.GT AT.AT AC.GT AC.GT AC.GT AT.AT AG.CT

10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10

31050640 31180813 31224357 31251517 31480790 31692892 31802041 31851266 31976701 31996849 31996849 32156204 32163926 32335382 32503085 32604334 32765995 32830312 32923147 32927870 32942866 32958465 32966547 33011054 33195079 33199519 33428441 33442343 33471020 33621572 33736479 33781409 34055560 34066589 34097263 34220671 34223293 34264504 34264504 34345284 34417999 34532000 34773258 34839027 34909221 35050049 35371334 35445376 35468402 35469040 35490880 35546911 35557876 35732493 35775502 35805499 35808865 36040314 36068403 36113255 36498424 37107687 37107687 37208291 37356048 37410805 37477310 37480574 37655646 37666431 37788592 38113167 38246547 38248250 38362200 38800439 38870894 39047295 39407315 39409019 39431874 39488831 39513791 39682266

31050653 31180823 31224375 31251532 31480811 31692903 31802055 31851284 31976720 31996867 31996867 32156224 32163949 32335391 32503094 32604355 32766015 32830323 32923162 32927881 32942895 32958479 32966565 33011068 33195093 33199533 33428457 33442365 33471033 33621588 33736502 33781424 34055586 34066610 34097277 34220692 34223303 34264530 34264530 34345307 34418023 34532012 34773280 34839042 34909243 35050063 35371353 35445410 35468427 35469067 35490900 35546921 35557888 35732511 35775521 35805510 35808875 36040340 36068417 36113273 36498439 37107716 37107716 37208304 37356063 37410828 37477335 37480596 37655665 37666449 37788616 38113179 38246557 38248277 38362211 38800449 38870912 39047318 39407329 39409038 39431889 39488860 39513820 39682280

4.66667 5.5 9.5 8 7.33333 6 7.5 4.75 10 4.75 4.75 7 12 5 5 4.4 7 6 4 6 15 3.75 4.75 7.5 3.75 3.75 4.25 11.5 7 3.4 4.8 5.33333 6.75 7.33333 3.75 5.5 5.5 6.75 6.75 4.8 5 6.5 5.75 5.33333 4.6 7.5 4 5.83333 13 5.6 10.5 5.5 6.5 4.75 10 6 5.5 13.5 3.75 9.5 5.33333 5 5 7 8 6 6.5 11.5 5 4.75 6.25 6.5 5.5 7 6 5.5 4.75 12 7.5 10 8 15 15 7.5

. . intergenic . . intergenic . . intergenic ENSSSCT00000031684 . promoter . . intergenic . . intergenic ENSSSCT00000011979 FBP1 intron ENSSSCT00000011982 FBP2 intron ENSSSCT00000026142 DAPK1 intron ENSSSCT00000026142 DAPK1 intron ENSSSCT00000011985 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011991 GOLM1 intron ENSSSCT00000011991 GOLM1 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000011993 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011996 NTRK2 intron ENSSSCT00000011995 NTRK2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000027988 UBQLN1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011999 FRMD3 intron ENSSSCT00000011999 FRMD3 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000012001 RASEF intron . . intergenic ENSSSCT00000012026 UBAP2 intron ENSSSCT00000025202SNORD121Apromoter . . intergenic . . intergenic ENSSSCT00000012035 . intron ENSSSCT00000012036 CHMP5 intron ENSSSCT00000012036 CHMP5 intron ENSSSCT00000012041 SMU1 intron ENSSSCT00000012041 SMU1 intron ENSSSCT00000012043 APTX intron ENSSSCT00000012045 NDUFB6 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

. . . 0.044 -0.181 0.035 -0.022 . . . . 0.041 . 0.828 -0.1 0.003 -0.312 0.17 -0.461 -0.12 0.145 0.589 . 0.724 . . . . . 0.13 -0.227 . -0.089 -0.281 -0.17 -0.064 0.1 -0.077 -0.077 0.746 . -0.029 0.211 0.247 . -0.035 -0.043 0.135 0.082 0.153 . . 0.157 -0.189 -0.23 . . 0.352 0.017 0.038 0.232 -0.231 -0.231 . 0.336 . 0.165 -0.333 . 0.316 0.186 0.008 -0.045 . 0.183 0.103 0.138 0.151 0.12 0.203 . -0.245 0.056 -0.188

rs788473766 rs793333513 rs786876858 180529 rs7911 rs793455068 rs791478951 rs788895371 999286 rs7898 rs790915979 rs792578163 rs792578163 rs791813333 . . rs793617288 rs789304099 rs790527237 . 532140 rs7898 rs790392673 rs792398287 rs786812595 rs793845191 rs793569321 881843 rs7867 rs787216146 rs787884701 . rs788560314 895555 rs7913 rs792376736 rs786972405 rs788715586 rs789839184 rs788584249 rs786530455 . 096454 rs7866 096454 rs7866 . rs786382970 319025 rs6905 rs793576689 rs788329598 143411 rs7868 156289 rs7899 rs786760116 rs787078489 045595 rs7867 rs791130341 163309 rs7929 rs793622590 . rs790744873 . rs786465848 297622 rs7918 969498 rs7900 rs694323775 977930 rs7921 rs793701877 . . rs786784548 . rs787755876 rs792920474 rs789806657 rs787365275 787172 rs7875 rs791910246 rs788084693 rs690988480 340732 rs7920 773173 rs7925 rs787349895 rs787116052 rs792957186 rs787020106 . rs786463274 . 350459 rs7864 rs793433799

2 2 2 3 2 4 5 2 2 2 2 2 4 2 2 2 3 2 3 2 2 2 2 3 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 4 2 2 2 2 2 2 4 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 4 2 4 4 2 2 2

AAG.CTT AC.GT AT.AT AAAC.GTTT AAC.GTT AAAT.ATTT AAAT.ATTT AAAC.GTTT AG.CT AGAT.ATCT AC.GT AT.AT AAAG.CTTT AAAT.ATTT AT.AT AAAT.ATTT AC.GT AT.AT AAT.ATT AAATT.AATTT AT.AT AC.GT AT.AT AT.AT AG.CT AAAAC.GTTTT AAAAG.CTTTT AT.AT AAC.GTT AAAC.GTTT AAAT.ATTT AT.AT AAC.GTT AG.CT AT.AT ATCC.GGAT AATT.AATT AT.AT AAAG.CTTT AAAC.GTTT AC.GT AAAAAT.ATTTTT AT.AT AAAC.GTTT AAAG.CTTT AAC.GTT AAAC.GTTT AGG.CCT AG.CT AT.AT AAAAAG.CTTTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AC.GT ACTC.GAGT ACTC.GAGT AC.GT AC.GT AAC.GTT AAC.GTT AGGG.CCCT AAAAG.CTTTT AAC.GTT AAC.GTT AC.GT AC.GT AC.GT AC.GT AC.GT AAAT.ATTT AT.AT AT.AT AAC.GTT AAAC.GTTT AC.GT AT.AT AT.AT AAAG.CTTT ACAG.CTGT AAAAT.ATTTT AG.CT AC.GT AAC.GTT

10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10

39725120 39881437 40117962 40255975 40282082 40379626 40388506 40394036 40414050 40587363 40628276 40806803 40840925 40845190 40878006 41051394 41103005 41197409 41390706 41433941 41490324 41703941 41785739 41814503 41971237 41984045 42094548 42238136 42307921 42572964 42579574 42710756 42715172 42803133 43057593 43092041 43410121 43527201 43684762 43760330 43805459 43806696 43913986 43925829 44024024 44053925 44657796 44693898 44755711 44826432 45029561 45118050 45118050 45118050 45243640 45385967 45385967 45394370 45394370 45424173 45424173 45571974 45716852 45917218 45917218 45945136 45945136 45984606 45984606 46130066 46170265 46301895 46482587 46576031 46616398 46947134 46957538 46973893 47281806 47282471 47953291 48014021 48252393 48386158

39725135 39881447 40117991 40255997 40282099 40379640 40388527 40394073 40414070 40587404 40628291 40806830 40840939 40845207 40878017 41051423 41103023 41197420 41390729 41433955 41490333 41703954 41785748 41814517 41971251 41984065 42094573 42238147 42307936 42572978 42579594 42710778 42715188 42803163 43057607 43092055 43410135 43527218 43684777 43760343 43805471 43806721 43913996 43925847 44024044 44053937 44657814 44693916 44755722 44826442 45029588 45118066 45118066 45118066 45243652 45385981 45385981 45394384 45394384 45424186 45424186 45571994 45716868 45917244 45917244 45945146 45945146 45984634 45984634 46130084 46170287 46301905 46482601 46576047 46616410 46947153 46957548 46973905 47281824 47282497 47953306 48014039 48252407 48386171

5.33333 5.5 15 5.75 6 3.75 5.5 9.5 10.5 10.5 8 14 3.75 4.5 6 7.5 9.5 6 8 3 5 7 5 7.5 7.5 4.2 5.2 6 5.33333 3.75 5.25 11.5 5.66667 15.5 7.5 3.75 3.75 9 4 3.5 6.5 4.33333 5.5 4.75 5.25 4.33333 4.75 6.33333 6 5.5 4.66667 4.25 4.25 4.25 6.5 3.75 3.75 7.5 7.5 4.66667 4.66667 5.25 3.4 9 9 5.5 5.5 14.5 14.5 9.5 5.75 5.5 7.5 5.66667 3.25 10 5.5 6.5 4.75 6.75 3.2 9.5 7.5 4.66667

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000034425 ENSSSCT00000033487 ENSSSCT00000033089 . ENSSSCT00000024823 ENSSSCT00000012062 ENSSSCT00000024823 ENSSSCT00000012062 ENSSSCT00000024823 ENSSSCT00000012062 . . ENSSSCT00000012064 ENSSSCT00000012066 ENSSSCT00000012064 ENSSSCT00000012066 ENSSSCT00000012064 ENSSSCT00000012066 . . . . ENSSSCT00000035562 ENSSSCT00000035562 . . . ENSSSCT00000012069 ENSSSCT00000012069 ENSSSCT00000012072 . . .

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . MAP3K8 MAP3K8 MAP3K8 . KIAA1462 KIAA1462 KIAA1462 KIAA1462 KIAA1462 KIAA1462 . . SVIL SVIL SVIL SVIL SVIL SVIL . . . . ZEB1 ZEB1 . . . KIF5B KIF5B CUBN . . .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic promoter promoter intron intron intron intron intergenic intergenic intron intron intron intron intron intron intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic

. . . . . 0.157 . . . 0.036 0.044 -0.089 . . -0.131 0.116 . -0.042 . . 0.174 . 0.445 0.18 . 0.168 0.113 . -0.161 -0.076 -0.05 . . 0.069 0.024 0.142 -0.169 . -0.085 0.242 . . . . 0.097 0.106 -0.271 -0.064 0.009 -0.035 . 0.492 0.492 0.492 . -0.17 -0.17 -0.066 -0.066 -0.157 -0.157 . -0.082 -0.084 -0.084 -0.653 -0.653 -0.273 -0.273 . 0.308 . 0.239 0.267 0.116 . . 0.141 0.291 . 0.05 -0.073 0.215 0.77

rs788722477 rs793397347 . 610030 rs7899 rs788220660 . rs792137424 rs791673532 rs788254004 rs788132469 758910 rs7919 rs788584603 . . 282637 rs7888 rs788506665 rs790867697 rs792852727 . 071375 rs7894 rs789519210 rs789643408 702068 rs7917 rs792953018 rs791942931 rs790168878 rs786694622 rs787338091 rs789324582 rs792021027 566930 rs7893 704899 rs7926 rs708403384 894620 rs7891 . . rs792797493 rs789051924 870954 rs7907 rs792541828 378933 rs7921 rs790717523 rs792944589 160805 rs7916 rs793786850 603606 rs7926 rs791141472 . . 733091 rs7865 rs792891109 rs793489797 rs793489797 rs793489797 268936 rs7911 rs790486082 rs790486082 . . rs790099975 rs790099975 rs789875897 rs788109735 rs791084106 rs791084106 rs789625042 rs789625042 rs789703627 rs789703627 . rs790796770 rs789540306 . rs792287309 rs793107734 . 380583 rs7908 . 455021 rs7863 358657 rs7865 rs787458564 376695 rs7902 060711 rs7873 rs788364054

2 2 2 2 2 2 2 2 2 4 3 4 2 2 3 2 7 3 2 2 2 5 2 2 4 2 2 2 2 2 2 2 2 2 4 2 2 2 4 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 3 2 2 2 2 2 4 2 2 3 2 2 2 2 2 2 4 2

AAAAAG.CTTTTT AGAT.ATCT AG.CT AAC.GTT AC.GT AAAC.GTTT AACC.GGTT AAAC.GTTT AC.GT AAAG.CTTT AAAT.ATTT AT.AT AC.GT AAT.ATT AAAG.CTTT AAT.ATT AT.AT AAAAC.GTTTT AAAG.CTTT AC.GT AAAC.GTTT AGATAT.ATATCT ACATG.CATGT AAAT.ATTT AT.AT AAAT.ATTT AC.GT ATCC.GGAT AT.AT AG.CT AGGG.CCCT AGG.CCT AGG.CCT AAAT.ATTT AC.GT ACAG.CTGT AG.CT AC.GT AT.AT AG.CT AG.CT AT.AT AG.CT AC.GT AC.GT AAAT.ATTT AAAAG.CTTTT AT.AT AAAC.GTTT AAC.GTT AAAT.ATTT ATC.GAT AAAT.ATTT AAAT.ATTT AAAG.CTTT AT.AT AAAAAC.GTTTTT AAAT.ATTT AC.GT AAAT.ATTT AAAAAC.GTTTTT AG.CT AAC.GTT AAAC.GTTT AT.AT AAG.CTT AAAT.ATTT AT.AT ACAG.CTGT ACAG.CTGT ACAG.CTGT AC.GT AAAT.ATTT AATG.CATT AAAT.ATTT AAC.GTT AAC.GTT AAAC.GTTT AAT.ATT AG.CT AAC.GTT AG.CT AAC.GTT AAAAG.CTTTT

10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10

48607761 48625461 48730794 48758514 48893453 48901524 48970206 49086444 49231913 49412392 49461371 49654268 49665013 49734174 49925942 50013983 50073533 50169484 50174660 50218384 50395728 50471954 50603290 50678361 50738139 50802875 50835571 50986655 51182090 51212597 51455957 51595725 51595725 51809083 51855840 52068045 52391721 52396442 52397734 52467943 52491127 52547146 52550689 52797217 53122060 53357554 53696426 53808752 54023464 54120513 54560177 54565508 54574195 54599132 54725088 54812566 54818557 54822690 54926351 54942573 54971915 55015962 55030349 55104315 55497997 55566380 55778706 55872840 56063685 56063685 56063685 56257227 56422321 56518488 57350240 57578893 57650685 57687456 57691147 57789047 58155533 58199022 58219431 58325441

48607786 48625483 48730803 48758534 48893463 48901546 48970219 49086462 49231926 49412407 49461387 49654279 49665032 49734187 49925954 50014000 50073544 50169502 50174674 50218396 50395749 50471986 50603314 50678378 50738148 50802894 50835590 50986677 51182100 51212611 51455975 51595741 51595741 51809098 51855850 52068071 52391734 52396463 52397745 52467960 52491144 52547157 52550707 52797227 53122074 53357574 53696452 53808761 54023482 54120532 54560195 54565527 54574212 54599146 54725106 54812577 54818575 54822712 54926360 54942584 54971941 55015972 55030365 55104330 55498017 55566394 55778720 55872850 56063707 56063707 56063707 56257247 56422337 56518507 57350254 57578906 57650702 57687478 57691161 57789064 58155549 58199035 58219450 58325461

4.33333 5.75 5 7 5.5 5.75 3.5 4.75 7 4 4.25 6 10 4.66667 3.25 6 6 3.8 3.75 6.5 5.5 5.5 5 4.5 5 5 10 5.75 5.5 7.5 4.75 5.66667 5.66667 4 5.5 6.75 7 11 6 9 9 6 9.5 5.5 7.5 5.25 5.4 5 4.75 6.66667 4.75 6.66667 4.5 3.75 4.75 6 3.16667 5.75 5 3 4.5 5.5 5.66667 4 10.5 5 3.75 5.5 5.75 5.75 5.75 10.5 4.25 5 3.75 4.66667 6 5.75 5 9 5.66667 7 6.66667 4.2

ENSSSCT00000012078 . intron . . intergenic . . intergenic ENSSSCT00000012080 . intron ENSSSCT00000012082 H242-21O2 intron ENSSSCT00000012082 H242-21O2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000012085 . intron ENSSSCT00000012085 . intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000026176 . intron ENSSSCT00000026176 . intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000012089 FAM188A intron ENSSSCT00000012089 FAM188A intron . . intergenic ENSSSCT00000012090 ITGA8 intron ENSSSCT00000012090 ITGA8 intron ENSSSCT00000012091 FAM171A1 intron ENSSSCT00000012091 FAM171A1 intron ENSSSCT00000024077 RPP38 intron ENSSSCT00000012093 DCLRE1C cds ENSSSCT00000012093 DCLRE1C intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000012100 . intron ENSSSCT00000012114 MPP7 intron ENSSSCT00000026458 . intron . . intergenic . . intergenic ENSSSCT00000012110 YME1L1 promoter ENSSSCT00000012112 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000012103 MYO3A intron ENSSSCT00000012103 MYO3A intron ENSSSCT00000012103 MYO3A intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000012116 . intron ENSSSCT00000012118 ARHGAP21 intron ENSSSCT00000029464 ARHGAP21 intron ENSSSCT00000028075 ARHGAP21 intron ENSSSCT00000012119 KIAA1217 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000012124 ARMC3 intron ENSSSCT00000012124 ARMC3 intron ENSSSCT00000012124 ARMC3 intron . . intergenic ENSSSCT00000012127 SPAG6 intron ENSSSCT00000012127 SPAG6 intron ENSSSCT00000012127 SPAG6 intron . . intergenic

0.015 0.16 -0.129 -0.682 -0.27 -0.831 -0.012 . -0.092 -0.111 . . . . 0.103 -0.192 2.941 0.331 -0.165 -0.033 -0.089 -0.157 . 0.225 . -0.015 -0.03 -0.044 0.433 0.016 -0.121 0.731 0.731 . 0.079 0.143 0.156 -0.141 0.259 0.211 0.894 0.356 -0.067 . -0.032 . 0.181 . 0.181 0.134 0.352 0.067 0.138 0.2 . 0.075 1.311 0.323 0.208 0.265 -0.172 0.146 0.058 0.004 . . 0.022 0.28 0.125 0.125 0.125 . -0.129 -0.094 . -0.085 -0.069 0.223 . . . 0.119 0.1 0.059

rs694656015 623197 rs7929 rs793568983 983319 rs7922 . 799126 rs7903 591073 rs7876 rs790377612 rs691181848 rs786465961 rs789197907 114463 rs7862 rs791153623 rs789756776 872807 rs7931 977612 rs7869 rs788079614 rs792572016 rs787673008 529005 rs7862 163229 rs7862 rs788052573 rs791614895 rs790602660 rs790275020 819793 rs7921 . rs791287109 rs792364023 533993 rs7886 699592 rs7899 rs787346006 rs787346006 rs792459203 . 600737 rs7930 204346 rs7883 rs786860558 rs789271449 789224 rs7893 rs787756435 774432 rs7907 248980 rs7885 . rs789666518 387048 rs7887 902542 rs7869 . 075231 rs7883 345183 rs7865 714390 rs7902 rs790550532 rs790365345 264326 rs7938 rs793236715 . 464480 rs7897 rs788770853 . rs786557547 rs788357612 . 307906 rs7891 rs789420311 183017 rs7877 rs790324247 rs789331382 rs786577071 467272 rs7917 467272 rs7917 467272 rs7917 385117 rs7906 rs787226325 rs789791161 rs790037726 rs790361585 rs790802988 rs786264790 rs791591205 rs696633143 rs788912012 rs787436733 095354 rs7923 790618 rs7923

2 2 2 2 3 2 2 2 2 2 2 3 2 2 2 2 2 2 2 3 2 2 2 2 2 2 3 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 4 2 2 2 2 2 2 2 2 2 2 3 2 2 4 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 3 2 4 2 3 2 2

AAAAT.ATTTT AAAT.ATTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AG.CT AAAAG.CTTTT AAAAC.GTTTT AG.CT AAAG.CTTT AC.GT AAC.GTT AAAAT.ATTTT AAG.CTT AAG.CTT AAAC.GTTT AG.CT AAC.GTT AAC.GTT AAC.GTT AAAC.GTTT AT.AT AAGG.CCTT AGGGG.CCCCT AT.AT AT.AT AT.AT AT.AT AT.AT AT.AT AAAC.GTTT AAAAAC.GTTTTT AAAAAC.GTTTTT AAAC.GTTT AG.CT AC.GT AAAC.GTTT AC.GT AGG.CCT AAAC.GTTT AC.GT AC.GT AAAC.GTTT AAAT.ATTT AG.CT AAAAAG.CTTTTT AT.AT AGG.CCT AC.GT AC.GT AC.GT AC.GT AC.GT AC.GT AAC.GTT AAAAC.GTTTT AAAC.GTTT AC.GT AC.GT AAAAC.GTTTT AAGG.CCTT AC.GT AATG.CATT AAAAAT.ATTTTT ACCT.AGGT AAC.GTT ACAT.ATGT AAAT.ATTT AAAC.GTTT AAAG.CTTT AAAG.CTTT AC.GT AAAT.ATTT AAC.GTT AC.GT AT.AT AG.CT AAAT.ATTT AAAG.CTTT AG.CT AC.GT AC.GT AAAAC.GTTTT AAAC.GTTT

10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10

58406797 58508637 58526593 58745639 58853788 59146851 59451101 59529835 59756863 59791967 59807604 59899710 60015353 60463494 60540849 60665727 60842415 61035875 61047727 61151849 61388243 61417063 61528058 61544575 61759165 61759165 61759165 61759165 61759165 61759165 62129018 62169044 62191755 62840569 62869065 62973016 63094677 63303295 63349981 63628210 63753703 64327260 64461332 64510426 64728963 64754619 64755201 64993474 65042410 65149791 65264057 65294551 65300508 65359386 65403253 65668150 65900890 66200998 66335186 66530778 66676695 66738092 66907552 66985185 67260177 67803496 67929356 68008222 68193298 68206481 68302056 68330167 68336632 68416466 68639189 68782001 68883534 68951816 68996931 69106337 69139759 69229467 69232996 69394781

58406819 58508666 58526612 58745656 58853803 59146871 59451115 59529850 59756884 59791988 59807613 59899725 60015368 60463510 60540861 60665740 60842426 61035891 61047750 61151860 61388266 61417072 61528082 61544594 61759180 61759180 61759180 61759180 61759180 61759180 62129044 62169073 62191781 62840592 62869075 62973032 63094701 63303305 63349996 63628231 63753735 64327274 64461350 64510450 64728973 64754637 64755212 64993489 65042423 65149806 65264070 65294572 65300519 65359397 65403271 65668170 65900910 66201008 66335199 66530803 66676708 66738105 66907571 66985208 67260198 67803514 67929386 68008236 68193313 68206508 68302070 68330179 68336647 68416478 68639216 68782017 68883546 68951830 68996953 69106353 69139771 69229489 69233020 69394798

4.6 7.5 5 4.5 4 10.5 3 3.2 11 5.5 5 5.33333 3.2 5.66667 4.33333 3.5 6 5.66667 8 4 6 5 6.25 4 8 8 8 8 8 8 6.75 5 4.5 6 5.5 8.5 6.25 5.5 5.33333 5.5 16.5 7.5 4.75 6.25 5.5 3.16667 6 5.33333 7 8 7 11 6 6 6.33333 4.2 5.25 5.5 7 5.2 3.5 7 5 4 5.5 6.33333 7.75 3.75 4 7 3.75 6.5 4 4.33333 14 8.5 6.5 3.75 5.75 8.5 6.5 11.5 5 4.5

. . . ENSSSCT00000012132 ENSSSCT00000012132 . . . . . . . . . . . . . . . . . . . ENSSSCT00000033235 ENSSSCT00000035993 ENSSSCT00000012149 ENSSSCT00000034324 ENSSSCT00000034108 ENSSSCT00000035186 . . . ENSSSCT00000012150 ENSSSCT00000012150 ENSSSCT00000012150 . ENSSSCT00000012151 . ENSSSCT00000012155 . . . . . . . . . . . . . . . ENSSSCT00000029333 . . . . . . . . . . . . . . . . . . . . . . . . . . . .

. . . MLLT10 MLLT10 . . . . . . . . . . . . . . . . . . . NRP1 NRP1 NRP1 NRP1 NRP1 NRP1 . . . PARD3 PARD3 PARD3 . CUL2 . CCNY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intergenic intergenic intergenic intron intron intron intergenic 3'utr intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

. -0.072 0.357 0.409 0.103 0.216 -0.075 0.3 -0.004 0.243 -0.052 0.367 . -0.079 . . -0.098 . 0.208 0.008 . 0.299 0.165 -0.063 0.469 0.469 0.469 0.469 0.469 0.469 1.038 0.159 0.058 -0.062 -0.316 0.552 -0.045 0.192 . 0.042 0.201 -0.09 -0.104 0.041 . 0.341 0.27 0.077 -0.185 . . -0.582 . . -0.08 0.228 . 0.039 -0.306 . 0.085 -0.012 0.076 . -0.184 0.959 . 0.451 0.424 . 0.045 0.283 . . -0.045 0.524 . -0.036 . 0.31 -0.077 0.047 0.073 0.296

rs789959223 . rs788295614 rs787896746 rs793812793 . rs787115558 rs793106034 rs790861400 rs788438908 . rs793225345 . 285394 rs7920 rs786290967 rs792175717 940956 rs7920 430326 rs7867 rs791790437 189753 rs7868 rs789507038 . rs792621719 826061 rs7881 rs787042928 rs787042928 rs787042928 rs787042928 rs787042928 rs787042928 408966 rs7918 . rs697076905 . . . 982864 rs7937 . rs787349103 973215 rs7869 rs786733782 . rs787801440 rs793375663 rs786250222 rs792599884 rs789314756 825583 rs7938 736390 rs7892 . rs787257547 . rs788604638 . 737714 rs7883 rs787288743 rs789292636 . 297468 rs7930 rs791009543 020656 rs7931 rs787018054 rs787622682 923300 rs7870 rs790142788 524468 rs7918 rs792488980 904169 rs7932 rs787711089 . rs787058390 . rs790969819 . 402155 rs7923 . . rs787374607 564384 rs7894 rs786736389 . . 747801 rs7886 rs787423545

2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 3 3 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 3 2 2 3 2 4 2 3 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 3 6 2 3 2 2 4 4 4 2 2

AACT.AGTT AC.GT AAAC.GTTT AAAAAG.CTTTTT AC.GT AT.AT AC.GT AAAG.CTTT AAG.CTT AG.CT AAAC.GTTT AT.AT AAAAC.GTTTT AC.GT AAAC.GTTT AAAAC.GTTTT AAAAG.CTTTT AAAC.GTTT AAAT.ATTT AAAC.GTTT AC.GT AAAAAT.ATTTTT AC.GT AC.GT AAAGC.GCTTT AT.AT AG.CT AC.GT AT.AT AAG.CTT AAAAG.CTTTT AAAT.ATTT AAAC.GTTT AT.AT AAG.CTT AAAAAC.GTTTTT AAAG.CTTT AAAAC.GTTTT AATG.CATT AAAT.ATTT AAAAT.ATTTT AC.GT AC.GT AGG.CCT AAC.GTT AC.GT AC.GT AAC.GTT AAC.GTT AAAAC.GTTTT AAGAG.CTCTT AAAAT.ATTTT AAAT.ATTT AAAC.GTTT AAT.ATT AC.GT AC.GT AAC.GTT AAACC.GGTTT AAAAC.GTTTT AC.GT AAAC.GTTT AAAAT.ATTTT AT.AT AC.GT AAAAC.GTTTT AAAC.GTTT AAAG.CTTT AAAC.GTTT AC.GT AC.GT AAAC.GTTT AGC.GCT AAAC.GTTT AAAAC.GTTTT AAAG.CTTT AC.GT AC.GT AC.GT AC.GT AT.AT AC.GT AC.GT AAAC.GTTT

10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 10 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11

69430469 69646208 69759936 69779442 69889437 69919784 70006509 70291679 70390471 70582338 70824252 70826704 70990863 71470792 71700955 72158058 72206739 72263403 72272502 72446649 72935764 72972121 73123504 74091722 74098179 74468600 75274833 75663532 75980130 76123979 76234735 76304158 76416463 76603122 76845150 76992808 77000415 77246982 77330262 77396937 77513083 77692029 78597958 78604603 48127 173765 173765 179545 179545 526787 629980 713097 1161722 1220048 1287713 2031634 2074625 2084873 2454264 2728499 2839620 3082399 3121848 3606511 3717410 3865911 4073777 4240543 4542370 5092717 5335328 5409527 5497293 5620441 5915402 5924888 6172173 6172173 6224898 6577039 6762968 6813037 7113892 7240921

69430483 69646219 69759950 69779464 69889447 69919794 70006520 70291694 70390488 70582348 70824271 70826718 70990887 71470808 71700968 72158076 72206758 72263422 72272522 72446668 72935776 72972138 73123517 74091732 74098202 74468610 75274845 75663542 75980145 76123990 76234750 76304180 76416485 76603135 76845168 76992830 77000433 77247005 77330278 77396954 77513099 77692045 78597971 78604623 48142 173778 173778 179560 179560 526810 629997 713117 1161750 1220062 1287737 2031647 2074644 2084889 2454284 2728514 2839640 3082410 3121865 3606520 3717422 3865940 4073797 4240559 4542391 5092727 5335339 5409545 5497309 5620459 5915422 5924900 6172187 6172187 6224910 6577052 6762984 6813051 7113904 7240947

3.75 6 3.75 3.83333 5.5 5.5 6 4 6 5.5 5 7.5 5 8.5 3.5 3.8 4 5 5.25 5 6.5 3 7 5.5 4.8 5.5 6.5 5.5 8 4 3.2 5.75 5.75 7 6.33333 3.83333 4.75 4.8 4.25 4.5 3.4 8.5 7 7 5.33333 7 7 5.33333 5.33333 4.8 3.6 4.2 7.25 3.75 8.33333 7 10 5.66667 4.2 3.2 10.5 3 3.6 5 6.5 6 5.25 4.25 5.5 5.5 6 4.75 5.66667 4.75 4.2 3.25 7.5 7.5 6.5 7 8.5 7.5 6.5 6.75

. ENSSSCT00000012178 . ENSSSCT00000012181 . . . . . ENSSSCT00000012183 . . . . . . . . . . . . . . . . ENSSSCT00000012222 ENSSSCT00000012224 . . ENSSSCT00000012228 ENSSSCT00000012228 . . . . ENSSSCT00000012233 . . . . ENSSSCT00000023307 . ENSSSCT00000028985 ENSSSCT00000010149 ENSSSCT00000024896 ENSSSCT00000030327 ENSSSCT00000024896 ENSSSCT00000030327 . . ENSSSCT00000010161 . . . . ENSSSCT00000010177 ENSSSCT00000010177 . . ENSSSCT00000031012 . . . . . . . . . ENSSSCT00000010212 ENSSSCT00000010212 . . ENSSSCT00000024217 ENSSSCT00000024217 ENSSSCT00000029859 ENSSSCT00000010215 . . ENSSSCT00000010220 . . .

. TAF3 . . . . . . . PRKCQ . . . . . . . . . . . . . . . . ADARB2 LARP4B . . ZYMND11 ZYMND11 . . . . CTSL . . . . OPTN . . GULDH IL17D IL17D IL17D IL17D . . FGF9 . . . . . . . . . . . . . . . . . . FLT1 FLT1 . . . . MTUS2 MTUS2 . . KATNAL1 . . .

intergenic intron intergenic intron intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intron intron intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intron intergenic exon intron intron intron intron intron intergenic intergenic intron intergenic intergenic intergenic intergenic intron intron intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intron intron intron intron intergenic intergenic intron intergenic intergenic intergenic

-0.02 -0.002 -0.05 -0.004 -0.155 -0.064 0.82 -0.136 0.431 . -0.305 0.128 . 0.152 . . 0.205 0.292 -0.16 0.008 . -0.501 -0.251 -0.159 -0.114 . -0.007 -0.197 0.152 . . -0.233 . . . -0.092 0.307 . 0.186 0.073 0.243 -0.099 . . . . . . . 0.114 0.315 0.579 0.043 -0.069 . . . . -0.27 -0.128 -0.157 -0.145 . . 0.032 . -0.112 -0.247 . . -0.119 0.085 0.212 0.039 -0.078 . -0.186 -0.186 -0.027 0.423 0.103 0.176 . -0.2

017687 rs7936 rs791090906 rs789222515 rs789232732 rs786962421 . rs788105202 rs789849736 rs790943582 765738 rs7865 958095 rs7891 rs793280060 rs787727998 rs790157304 rs789310337 . 487674 rs7870 815794 rs7937 rs786863476 . rs786588170 rs793361411 rs793192092 286392 rs7891 rs787337571 rs789126447 529966 rs7919 rs788506794 rs790993763 rs786493516 rs788569249 rs792192209 rs793492560 rs792796894 rs787378782 941328 rs7871 631463 rs7892 476478 rs7880 rs790105139 rs787882693 rs788604446 681484 rs7920 rs787085042 . rs791505587 . . . . 240979 rs7896 rs792550281 rs792382611 rs792859607 rs791323010 312886 rs7863 rs787994511 rs786953761 rs791918534 rs787189329 rs790783683 rs788563464 927783 rs7870 rs786298174 628213 rs7866 069621 rs7877 rs786657393 rs690065995 rs786762049 rs792330356 rs788819692 rs791393148 rs791998111 rs788173357 rs789381153 rs787130959 923595 rs7902 rs788825312 rs788825312 rs788871162 rs792182315 rs790535074 . rs786795307 440471 rs7928

2 2 2 3 2 2 2 2 2 4 2 2 2 3 2 2 2 2 2 3 2 2 2 3 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 4 3

AG.CT AAAT.ATTT AAT.ATT AAAAAC.GTTTTT AAAAC.GTTTT AT.AT AT.AT AC.GT AAAC.GTTT AG.CT AAAC.GTTT AG.CT AAG.CTT AT.AT AAAG.CTTT AT.AT AC.GT AAAC.GTTT ATC.GAT AC.GT ACAT.ATGT AAC.GTT AAC.GTT AAAT.ATTT AAAAT.ATTTT AC.GT AAAT.ATTT AAAC.GTTT AAAAT.ATTTT AC.GT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAG.CTT AG.CT AG.CT AAG.CTT AC.GT AAAT.ATTT AC.GT AC.GT AT.AT AC.GT AAAC.GTTT AAC.GTT AG.CT AAC.GTT AG.CT AT.AT AT.AT AC.GT AAACC.GGTTT AGG.CCT AC.GT AAC.GTT ACACTC.GAGTG AC.GT AAAC.GTTT AAAAC.GTTTT AT.AT AACC.GGTT AC.GT AAAC.GTTT AAAAC.GTTTT AT.AT AG.CT AG.CT AAAC.GTTT AAAG.CTTT AC.GT AC.GT AAAAAG.CTTTTT AT.AT AAAAC.GTTTT AAT.ATT AC.GT AT.AT AAC.GTT AAAC.GTTT AAAC.GTTT AC.GT AAC.GTT AAT.ATT AG.CT

11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11

7261798 7265500 7327657 7370972 7761984 7807629 8386484 8495208 8505761 8638241 8884963 9192876 9800493 9878160 10123165 10171645 10303756 10385783 10431280 10512727 11028749 11128046 11380132 11450710 11517590 11527631 11558725 11640659 12072180 12333658 12463676 12530159 12670543 12718804 12770068 12949265 12977745 13272953 13305521 13429379 13473100 13618282 13697316 13832392 13856430 13996940 14108541 14196016 14293417 14293417 14680800 14954957 14979844 15131694 15358219 15492873 15544903 15685085 15892168 15901059 16093944 16133664 16199636 16276011 16338317 16384835 16441365 16450065 16564139 16684915 16740223 16758952 16777069 16896321 17124401 17232563 18311367 18325102 18478741 18529356 18564081 18613504 19000744 19089767

7261810 7265525 7327668 7370994 7762007 7807641 8386493 8495222 8505780 8638257 8884986 9192886 9800514 9878170 10123185 10171662 10303771 10385801 10431295 10512737 11028764 11128059 11380145 11450728 11517608 11527643 11558756 11640673 12072197 12333672 12463694 12530178 12670565 12718817 12770080 12949278 12977760 13272967 13305540 13429395 13473118 13618291 13697325 13832406 13856446 13996972 14108554 14196030 14293444 14293444 14680812 14954971 14979859 15131705 15358232 15492895 15544917 15685107 15892191 15901077 16093960 16133676 16199650 16276034 16338326 16384847 16441374 16450079 16564168 16684931 16740233 16758971 16777078 16896335 17124414 17232576 18311380 18325118 18478755 18529378 18564097 18613522 19000761 19089777

6.5 6.5 4 3.83333 4.8 6.5 5 7.5 5 8.5 6 5.5 7.33333 5.5 5.25 9 8 4.75 5.33333 5.5 4 4.66667 4.66667 4.75 3.8 6.5 8 3.75 3.6 7.5 4.75 5 5.75 4.66667 6.5 7 5.33333 7.5 5 8.5 9.5 5 5 3.75 5.66667 16.5 4.66667 7.5 14 14 6.5 3 5.33333 6 4.66667 3.83333 7.5 5.75 4.8 9.5 4.25 6.5 3.75 4.8 5 6.5 5 3.75 7.5 8.5 5.5 3.33333 5 3 4.66667 7 7 5.66667 3.75 5.75 8.5 6.33333 6 5.5

ENSSSCT00000010224 ENSSSCT00000010224 . . . ENSSSCT00000010230 . ENSSSCT00000010234 ENSSSCT00000010234 ENSSSCT00000032040 . . . . ENSSSCT00000010246 ENSSSCT00000010246 . . . . . . . ENSSSCT00000010247 ENSSSCT00000010247 ENSSSCT00000010247 ENSSSCT00000010247 ENSSSCT00000010247 . . . . ENSSSCT00000010254 . . . . . ENSSSCT00000010259 ENSSSCT00000010259 ENSSSCT00000010259 . . . . ENSSSCT00000010261 ENSSSCT00000010261 ENSSSCT00000010261 ENSSSCT00000010264 ENSSSCT00000024776 . . . . . . ENSSSCT00000010267 ENSSSCT00000010267 ENSSSCT00000010271 . . ENSSSCT00000010277 ENSSSCT00000010279 . . . . . . . ENSSSCT00000010282 ENSSSCT00000010282 ENSSSCT00000010282 . . . ENSSSCT00000010292 ENSSSCT00000010292 ENSSSCT00000023143 ENSSSCT00000010295 ENSSSCT00000010295 . ENSSSCT00000026092 ENSSSCT00000028831

ALOX5AP ALOX5AP . . . B3GALTL . FRY FRY . . . . . RFC3 RFC3 . . . . . . . . . . . . . . . . SMAD9 . . . . . TRPC4 TRPC4 TRPC4 . . . . FREM2 FREM2 FREM2 . . . . . . . . FOXO1 FOXO1 . . . NEK5 ALG11 . . . . . . . INTS6 INTS6 INTS6 . . . EBPL EBPL RCBTB1 PHF11 PHF11 . FNDC3A .

intron intron intergenic intergenic intergenic intron intergenic intron promoter intron intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intergenic promoter intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic 3'utr intron intron intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intron intron intron intron intron intergenic intron intron

-0.037 . 0.152 -0.242 0.161 0.371 . 1.264 1.618 -0.042 . 0.059 0.435 0.073 0.003 . -0.1 0.1 0.067 0.035 0.036 -0.025 0.125 -0.104 . -0.155 -0.223 0.448 0.101 -0.053 . 0.152 0.057 0.024 . 0.214 0.132 -0.142 -0.129 0.032 . -0.521 . . . 0.004 0.063 -0.072 -0.082 -0.082 -0.092 0.135 0.204 0.076 0.146 0.092 1.03 0.18 -0.784 -0.986 . 0.048 0.287 0.111 . -0.126 -0.058 0.134 0.271 0.201 0.347 0.033 1.368 . 0.297 0.048 0.079 . -0.224 0.851 0.141 -0.182 0.187 .

367292 rs7912 rs787577610 . rs789092509 rs788713702 rs793226828 rs790016370 rs793092356 . 675220 rs7928 rs792037397 624280 rs7869 rs790766612 rs788356695 608077 rs7932 . . 429296 rs7930 . rs789388232 . . rs790500902 rs786547237 rs790064464 rs787336372 rs789870668 rs787251379 rs789085784 rs787914685 194290 rs7888 rs792622607 353914 rs7938 rs791623841 rs792815622 rs791273572 . rs787500556 rs789084227 415444 rs7916 rs696734017 rs788121657 . 794689 rs7926 . rs708630237 rs786551136 rs793509467 rs789313544 rs789313544 027918 rs7927 683008 rs7885 rs787098870 . rs792733912 rs788445609 457116 rs7887 976749 rs7917 520434 rs7901 . rs789986051 280659 rs7864 746274 rs7875 rs696233964 rs788637544 rs790796250 . rs787115795 . rs789649934 . rs791808133 rs787718591 rs793238884 rs791755326 rs790302347 rs788887634 rs792964408 rs789709781 rs711546293 . 719806 rs7904 rs791535583 rs790528832

3 2 2 2 2 2 2 2 2 2 2 3 2 3 2 2 4 2 2 2 2 3 2 2 2 2 2 2 2 4 3 2 3 2 2 2 2 2 4 3 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 3 3 2 3 2 3 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 3

AAAC.GTTT AT.AT AAAG.CTTT AAAAC.GTTTT AC.GT AGC.GCT AC.GT AC.GT AT.AT AAAC.GTTT AAAC.GTTT AAC.GTT AAG.CTT AAAAT.ATTTT AAAG.CTTT AAAAG.CTTTT AAAC.GTTT AC.GT AAAT.ATTT AAAAT.ATTTT AGAT.ATCT AAC.GTT AAAC.GTTT AT.AT AAAC.GTTT AAAC.GTTT AAAT.ATTT AATT.AATT AAAAT.ATTTT AC.GT AG.CT AC.GT AG.CT AAAT.ATTT AAAAC.GTTTT AAT.ATT AC.GT AAT.ATT AAT.ATT AAAT.ATTT AG.CT AG.CT AC.GT AC.GT AAAC.GTTT AAC.GTT AC.GT AT.AT AG.CT AAAC.GTTT AC.GT AG.CT AAAC.GTTT AGC.GCT AAAC.GTTT AT.AT AAAAAC.GTTTTT AC.GT AC.GT AAAC.GTTT AT.AT AAAC.GTTT AAAG.CTTT AAT.ATT AAAC.GTTT AAAAC.GTTTT AAC.GTT AT.AT AT.AT AAAT.ATTT AC.GT AT.AT AT.AT AAAC.GTTT AAC.GTT AC.GT AC.GT AT.AT AAAT.ATTT AAAAC.GTTTT AG.CT AG.CT AAT.ATT AT.AT

11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11

19114449 19139264 19253226 19853189 20183804 20446227 20455025 20640661 20749734 21268858 21310697 21468078 21469497 21484118 21689334 22082573 22337264 22337353 22461467 22468046 22509881 22660462 22768463 22806354 23449346 23654817 23755167 23785863 23903742 24147051 24473218 24535137 24541251 24554565 24663852 24830001 24877976 25005858 25247825 25274744 25436112 25914662 26101626 26185231 26225702 26589647 26643171 26983119 27303606 27397440 27747312 27799677 27843783 27855336 28135635 28341554 28350372 28467898 28518661 28546012 28565917 28580062 28792035 28809634 28967218 28988196 29091869 29104105 29211050 29388288 29436202 29475683 29572459 29575436 29614715 29635635 29668971 29712914 29816187 29964172 30376827 30640523 30679625 30861001

19114470 19139274 19253239 19853212 20183814 20446238 20455053 20640670 20749745 21268877 21310715 21468092 21469510 21484140 21689348 22082590 22337282 22337367 22461493 22468078 22509906 22660489 22768493 22806367 23449364 23654839 23755181 23785882 23903765 24147061 24473227 24535147 24541270 24554586 24663870 24830012 24877986 25005870 25247859 25274765 25436124 25914673 26101640 26185244 26225724 26589660 26643215 26983134 27303616 27397463 27747323 27799716 27843803 27855349 28135651 28341567 28350390 28467910 28518684 28546027 28565932 28580076 28792048 28809650 28967251 28988222 29091885 29104118 29211067 29388310 29436213 29475693 29572469 29575448 29614735 29635644 29668981 29712927 29816209 29964196 30376844 30640537 30679636 30861013

5.5 5.5 3.5 4.8 5.5 4 14.5 5 6 5 4.75 5 4.66667 4.6 3.75 3.6 4.75 7.5 6.75 6.6 6.5 9.33333 7.75 7 4.75 5.75 3.75 5 4.8 5.5 5 5.5 10 5.5 3.8 4 5.5 4.33333 11.6667 5.5 6.5 6 7.5 7 5.75 4.66667 22.5 8 5.5 6 6 20 5.25 4.66667 4.25 7 3.16667 6.5 12 4 8 3.75 3.5 5.66667 8.5 5.4 5.66667 7 9 5.75 6 5.5 5.5 3.25 7 5 5.5 7 5.75 5 9 7.5 4 6.5

ENSSSCT00000028831 . intron ENSSSCT00000028831 . intron . . intergenic ENSSSCT00000010302 ITM2B intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000010309 LRCH1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000022928 ENOX1 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000010334 DNAJC15 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000010337 AKAP11 intron ENSSSCT00000026550 . intron ENSSSCT00000031457 . intron . . intergenic . . intergenic ENSSSCT00000010343 MTRF1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

. . 0.721 0.085 0.057 -0.072 0.035 -0.085 . -0.03 0.415 . -0.089 0.243 -0.003 0.063 . . . -0.082 0.11 . 0.389 . 0.075 0.129 0.225 . -0.296 0.177 . -0.142 -0.155 0.123 0.168 . 0.009 0.406 . 0.025 0.229 0.101 0.304 0.532 . 1.243 0.977 -0.035 . 0.039 1.074 0.007 . 0.117 -0.005 . -0.116 0.008 . 0.088 -0.119 . -0.121 . 0.059 -0.075 1.44 . 0.017 . 0.169 -0.245 0.065 -0.033 0.279 -0.031 -0.019 0.292 . . -0.179 . . .

rs788346310 506124 rs7879 rs792397382 109866 rs7928 . rs789013524 099580 rs7913 . rs786823539 rs788881331 757241 rs7870 389123 rs7930 rs792867354 660002 rs7889 rs793141889 rs791741317 876684 rs7881 043048 rs7934 203537 rs7868 629457 rs7873 rs789987469 rs788091861 . rs788749462 . 412966 rs7923 rs789236549 rs793537936 rs788816977 rs792666490 rs710177075 944770 rs7908 rs793735416 rs792419758 rs788599592 rs793261158 . rs793614763 rs790576500 741642 rs7892 582247 rs7885 rs787756192 rs791177682 rs793359705 rs792635502 426583 rs7916 rs788493465 . rs790940477 rs693251157 986571 rs7905 rs787464622 rs791395234 . 846219 rs7935 839519 rs7874 rs789440481 rs788163006 034754 rs7917 rs793334926 836808 rs7888 rs786935309 rs709145132 227700 rs7905 rs790728000 rs791863553 251637 rs7872 rs792251561 rs788655755 795049 rs7905 rs792688635 390741 rs7905 rs793620402 rs792652355 rs790282037 rs792745543 rs788952389 . rs791466976 . rs791092084 rs792809471 rs786472790 789015 rs7918

2 2 2 2 5 2 3 3 2 3 2 2 2 2 2 2 2 5 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 3 2 2 2 2 2 2 2 2 2 2 2 2 3 4 3 2 2 2 2 2 4 2 2 3 2 2 2 2 2 2 2 3 2 2 3 2 2 2 2 2 2 3 2 5 2 2 3 2 2 2

AAAT.ATTT AT.AT AGGGG.CCCCT AC.GT AAT.ATT AAAAG.CTTTT AC.GT AAG.CTT AC.GT AAC.GTT AAAAC.GTTTT AC.GT AC.GT AT.AT AATG.CATT AC.GT AAT.ATT AAAG.CTTT AAAC.GTTT AC.GT AC.GT AAAC.GTTT ATAT.ATAT ACAT.ATGT AT.AT AG.CT AT.AT AC.GT AAAC.GTTT AAATAT.ATATTT AGAT.ATCT AT.AT AAAAC.GTTTT AGAT.ATCT AT.AT AAG.CTT AAAT.ATTT AAAT.ATTT AT.AT AAAC.GTTT AG.CT AAAAT.ATTTT AAAC.GTTT AAT.ATT AG.CT AT.AT AT.AT AAAT.ATTT AC.GT AAAAT.ATTTT AT.AT AATAC.GTATT AT.AT AAC.GTT AAT.ATT ATC.GAT AGG.CCT AAAC.GTTT AAAG.CTTT AT.AT AT.AT AC.GT AAAAAT.ATTTTT AATAT.ATATT AAAAAC.GTTTTT AC.GT AAAT.ATTT AAAC.GTTT AAC.GTT AAAC.GTTT AG.CT AAAAC.GTTTT AG.CT AT.AT ATCC.GGAT ACT.AGT AATT.AATT AAC.GTT AAAC.GTTT AAT.ATT AG.CT AAAAT.ATTTT AAAT.ATTT AAAAC.GTTTT

11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11

30969266 31292577 31514450 31691283 31955490 32344667 32435281 32567683 32722876 33185590 33548942 34495438 34576472 34658097 34769824 34817022 34964720 34972418 34978823 35011621 35510234 35518972 35809341 35900093 36016472 36029218 36179750 36605840 37129483 37367079 37975459 38284630 38495732 38583636 38996381 39582532 39741814 39844699 39909345 40122611 40599107 40749454 40989959 41048767 41139631 41184854 41606341 41737912 41765641 41891818 42068362 43094348 43252442 43407566 43420842 43452068 43490723 43558387 43585769 43886811 43975755 44041750 44175417 44401061 45005977 45042696 45054624 45554345 45627809 45643444 46116611 46141477 46149492 46221614 46268482 46287713 46293142 46463108 46553538 46672825 46734785 46777723 47215934 47548665

30969285 31292595 31514466 31691297 31955509 32344688 32435301 32567697 32722891 33185603 33548970 34495462 34576486 34658112 34769848 34817031 34964733 34972432 34978842 35011634 35510262 35518995 35809382 35900107 36016481 36029232 36179761 36605872 37129506 37367104 37975479 38284652 38495750 38583672 38996396 39582548 39741829 39844733 39909357 40122625 40599121 40749477 40989980 41048781 41139642 41184872 41606351 41737926 41765653 41891846 42068385 43094365 43252458 43407582 43420855 43452087 43490735 43558419 43585781 43886825 43975776 44041769 44175439 44401077 45006005 45042709 45054659 45554367 45627828 45643460 46116621 46141508 46149508 46221636 46268524 46287733 46293154 46463121 46553562 46672842 46734796 46777742 47215956 47548691

5 9.5 3.4 7.5 6.66667 4.4 10.5 5 8 4.66667 5.8 12.5 7.5 8 6.25 5 4.66667 3.75 5 7 14.5 6 10.5 3.75 5 7.5 6 16.5 6 4.33333 5.25 11.5 3.8 9.25 8 5.66667 4 8.75 6.5 3.75 7.5 4.8 5.5 5 6 9.5 5.5 3.75 6.5 5.8 12 3.6 8.5 5.66667 4.66667 6.66667 4.33333 8.25 3.25 7.5 11 10 3.83333 3.4 4.83333 7 9 5.75 6.66667 4.25 5.5 6.4 8.5 11.5 10.75 7 3.25 4.66667 6.25 6 6 4 5.75 5.4

. . . . . . . . . . . . . ENSSSCT00000010357 . . . . . ENSSSCT00000010359 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000010366 ENSSSCT00000010366 ENSSSCT00000010366 ENSSSCT00000010366 . . . . . .

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . KLHL1 KLHL1 KLHL1 KLHL1 . . . . . .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic

-0.047 0.051 . -0.063 . -0.111 . . 0.043 -0.029 -0.05 -0.275 -0.179 0.003 0.077 0.49 0.166 -0.014 . . 0.217 0.224 0.172 -0.245 . . . 0.088 1.031 . -0.1 . . 0.568 -0.306 0.128 . . . . -0.315 . . 0.084 -0.068 . -0.065 -0.105 . -0.031 0.029 0.714 . 0.337 -0.071 0.192 0.411 . -0.02 . -0.165 -0.043 . 0.096 -0.055 -0.014 . -0.426 . -0.004 0.104 -0.059 . -0.103 -0.177 0.036 0.069 -0.144 . -0.116 . -0.108 . .

. . . . 182780 rs7937 rs789114717 108267 rs7915 rs792108250 rs788594733 rs787864838 085462 rs7862 rs787504577 rs792083088 rs793469890 022008 rs7894 rs791821248 257744 rs7915 rs791606493 rs792404293 801514 rs7867 543058 rs7921 rs786229412 rs790830185 . rs793502107 rs691576979 rs789547208 212166 rs7913 696007 rs7887 . 311169 rs7878 rs787350232 427205 rs7911 . rs788231268 rs791639838 rs788040796 rs698100049 . . rs792043943 987226 rs7866 956349 rs7913 . . 166002 rs7932 rs793638147 rs788686791 . rs791500176 rs792871787 rs789114243 . . rs787352257 . 806342 rs7892 954101 rs7895 740128 rs7862 . 480922 rs7874 rs703129254 . . rs791573445 045889 rs7885 rs788414690 rs790907355 737671 rs7871 986492 rs7863 rs787909042 rs792684620 834297 rs7932 252566 rs7920 . rs793674111 460961 rs7887 rs792991936 rs791298226 rs792431749 rs787390780 rs787883830 206494 rs7886 996341 rs7866

2 2 2 2 2 2 2 3 2 3 2 2 2 2 2 2 2 2 2 4 4 3 2 2 2 2 2 3 2 2 2 2 2 2 3 2 2 2 2 4 2 2 2 2 2 2 4 2 3 2 2 2 3 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 3 3 3 2 4 2 2 2 2 2 2 2 2 2 2 2

AT.AT AT.AT AG.CT AAC.GTT AC.GT AAAC.GTTT ATC.GAT AAAG.CTTT AAC.GTT AT.AT AAAC.GTTT AC.GT AC.GT AACC.GGTT AAG.CTT AG.CT AG.CT AC.GT AAC.GTT AT.AT AAAC.GTTT AC.GT AAAC.GTTT AAAT.ATTT ATC.GAT AC.GT AAC.GTT AAT.ATT AT.AT AAAT.ATTT AAC.GTT AAC.GTT AAAC.GTTT AC.GT AT.AT AAC.GTT AAC.GTT AC.GT AAAT.ATTT AGC.GCT AC.GT AAAAT.ATTTT AG.CT AAAAC.GTTTT AAGG.CCTT AC.GT AAAT.ATTT AT.AT AC.GT AAAT.ATTT AG.CT AG.CT AAAT.ATTT AACC.GGTT AAC.GTT AAAC.GTTT AATG.CATT AT.AT AAAC.GTTT AAAC.GTTT AG.CT AAAAGG.CCTTTT AAAT.ATTT AG.CT AC.GT AAAAT.ATTTT AATT.AATT AAAT.ATTT AC.GT AC.GT AAC.GTT AAAC.GTTT AAAG.CTTT AAAC.GTTT AAAG.CTTT AT.AT AAAC.GTTT AAAAT.ATTTT AAAC.GTTT AT.AT AAAC.GTTT AC.GT AAT.ATT AAAC.GTTT

11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11

47619016 47688815 48334572 48357999 48470428 48641735 48701428 48847621 49058300 49331813 49545561 49605902 49707438 49952386 50012522 50033239 50310928 50414537 50476785 50597519 50597680 50708521 50999526 51214738 51247168 51325981 51456482 51700830 51717635 51795711 51854588 51893871 52026323 52111800 52161404 52303351 52443163 52452549 52522101 52803192 52834914 52886072 52931932 53042330 53105710 53197847 53202335 53369470 53589105 53611573 53635741 53718369 53822698 53846986 54142031 54157089 54211064 54259468 54260098 54295849 54305366 54312315 54585047 54598648 54675583 54707881 54714515 54876345 54996153 54998951 55094415 55222290 55245598 55248945 55506610 55964566 56228851 56397614 56730133 57088580 57315026 57949716 57993939 58121424

47619034 47688839 48334582 48358019 48470440 48641750 48701443 48847649 49058314 49331842 49545575 49605918 49707449 49952420 50012533 50033251 50310943 50414548 50476804 50597544 50597692 50708530 50999544 51214752 51247180 51325991 51456496 51700843 51717645 51795738 51854599 51893887 52026355 52111809 52161426 52303366 52443185 52452558 52522117 52803204 52834928 52886096 52931943 53042345 53105740 53197856 53202357 53369482 53589124 53611605 53635769 53718383 53822725 53847007 54142048 54157101 54211083 54259478 54260117 54295863 54305376 54312335 54585066 54598658 54675593 54707905 54714535 54876364 54996163 54998963 55094435 55222308 55245612 55248963 55506623 55964576 56228869 56397634 56730147 57088604 57315048 57949733 57993954 58121440

9.5 12.5 5.5 7 6.5 4 5.33333 7.25 5 15 3.75 8.5 6 8.75 4 6.5 8 6 6.66667 13 3.25 5 4.75 3.75 4.33333 5.5 5 4.66667 5.5 7 4 5.66667 8.25 5 11.5 5.33333 7.66667 5 4.25 4.33333 7.5 5 6 3.2 7.75 5 5.75 6.5 10 8.25 14.5 7.5 7 5.5 6 3.25 5 5.5 5 3.75 5.5 3.5 5 5.5 5.5 5 5.25 5 5.5 6.5 7 4.75 3.75 4.75 3.5 5.5 4.75 4.2 3.75 12.5 5.75 9 5.33333 4.25

. . intergenic . . intergenic ENSSSCT00000010367 . intron ENSSSCT00000010367 . intron ENSSSCT00000010367 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000010370 DIS3 intron ENSSSCT00000025113 . intron . . intergenic . . intergenic ENSSSCT00000010373 KLF5 promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000010376 . 3'utr . . intergenic ENSSSCT00000010377 UCHL3 intron ENSSSCT00000010377 UCHL3 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000010382 . intron ENSSSCT00000010386 MYCBP2 intron ENSSSCT00000010386 MYCBP2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000010387 SCEL promoter ENSSSCT00000010387 SCEL intron . . intergenic . . intergenic . . intergenic ENSSSCT00000010390 EDNRB intron ENSSSCT00000010390 EDNRB intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

-0.094 0.465 0.126 0.225 0.158 0.105 0.03 0.184 . 0.12 . 0.245 0.074 0.35 . -0.447 0.126 . 0.162 -0.048 0.004 -0.101 0.003 0.442 0.135 1.054 . . 0.859 0.262 . . 0.302 0.046 1.223 0.178 0.994 0.161 0.225 0.058 -0.046 0.038 -0.137 -0.036 0.127 0.008 0.165 0.092 0.188 . 0.098 0.066 3.303 0.182 0.229 . -0.024 -0.012 0.014 -0.105 0.189 0.044 . 0.097 . 0.011 0.253 0.104 0.52 . 0.015 0.068 0.031 0.27 0.15 . . . 0.324 -0.382 0.105 . 0.016 .

. 358123 rs7916 . 910035 rs7927 319428 rs7882 336576 rs7925 336282 rs7866 896798 rs7913 rs789915022 rs791672511 rs791290065 866436 rs7872 rs792514803 540418 rs7866 . 383083 rs7917 rs792201362 . rs789454701 . . rs786476259 rs789037479 rs790146137 rs791451231 rs693516300 . rs788659090 297748 rs7868 rs789639136 . rs791205663 rs792280597 rs790249605 rs788854435 rs787407054 rs788554344 581217 rs7930 rs792502294 rs791454439 . . rs786357461 rs786937544 rs787443944 . rs787320216 rs786717608 290420 rs7869 rs786477143 rs793689260 rs789601831 rs788500524 . rs791807607 rs792531550 609688 rs7889 rs791600090 163856 rs7928 rs789180678 rs791294894 506143 rs7933 559178 rs7923 rs791961709 rs790811785 rs793728456 rs787308011 rs787373665 362625 rs7879 . rs711970894 rs793672930 . rs789503557 rs790021609 rs788370548 rs793509576 533393 rs7916 rs788545978 rs789107174 245168 rs7930 rs786316012 rs787313452 307428 rs7898

4 3 2 4 3 2 2 2 2 2 3 2 2 2 4 2 2 3 2 2 2 2 2 2 2 2 2 2 3 2 2 3 2 2 2 3 3 2 2 2 4 2 3 2 2 3 2 2 2 2 3 2 2 2 2 3 2 2 2 2 3 2 2 4 2 2 2 2 4 3 4 2 2 2 2 3 2 2 2 2 2 2 2 2

AT.AT AAAT.ATTT AC.GT AC.GT ACAT.ATGT AC.GT AC.GT ACAT.ATGT AC.GT ACAT.ATGT AC.GT AAT.ATT AAAAAC.GTTTTT AAC.GTT AAC.GTT AGAT.ATCT AT.AT AGATAT.ATATCT AAT.ATT AC.GT AC.GT ACT.AGT AC.GT AAC.GTT AC.GT AATCAT.ATGATT AAT.ATT AC.GT AAAT.ATTT AT.AT AT.AT AG.CT AAAC.GTTT AT.AT AAAC.GTTT AC.GT AAAC.GTTT AAAAC.GTTTT AAAC.GTTT AG.CT AAAC.GTTT AAAAG.CTTTT AG.CT AAAT.ATTT AAT.ATT AAAT.ATTT AG.CT AGAT.ATCT AAAAG.CTTTT AAAAT.ATTTT AC.GT AAC.GTT AT.AT AAAT.ATTT AAAT.ATTT AT.AT AG.CT AAC.GTT AAAC.GTTT AT.AT AC.GT AGG.CCT AC.GT AAAT.ATTT AC.GT AAAC.GTTT AAAAAG.CTTTTT AC.GT AG.CT AC.GT AATG.CATT AG.CT AT.AT AAAAC.GTTTT AT.AT AACAC.GTGTT AT.AT AAAC.GTTT AAAC.GTTT AG.CT AAAG.CTTT AAAC.GTTT AC.GT AAAT.ATTT

11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11

58121878 58349296 58606794 58673662 58757785 58784694 58908779 59027556 59107172 59239166 59742691 59865388 59880261 59881878 59914265 60002283 60071584 60273524 60290366 60954777 61009553 61317930 61478654 61863097 62040996 62057913 62379063 62407235 62413126 62511453 62624152 62732136 62931150 63053264 63397968 63491168 63983089 63994264 64362345 64478616 64711838 64713743 64726172 64864352 64878754 65196714 65203040 65233463 65238356 65486311 65519291 65558343 65787088 66022913 66129072 66362320 66401370 66511995 66575337 66632955 66784757 67193534 67488093 67678307 67749266 67851292 67868619 67892707 67973037 67977820 68355150 68472410 68582233 68582815 68737766 68906543 68912984 69169147 69434036 69477431 69532691 69707678 69723506 69848910

58121911 58349322 58606806 58673693 58757800 58784707 58908790 59027571 59107190 59239178 59742703 59865418 59880283 59881892 59914279 60002303 60071604 60273546 60290383 60954790 61009572 61317948 61478669 61863111 62041008 62057933 62379078 62407256 62413143 62511470 62624161 62732150 62931164 63053273 63397990 63491190 63983111 63994287 64362379 64478638 64711853 64713761 64726182 64864373 64878773 65196744 65203057 65233479 65238374 65486331 65519306 65558360 65787097 66022928 66129098 66362330 66401382 66512007 66575361 66632972 66784778 67193552 67488103 67678321 67749278 67851318 67868637 67892727 67973048 67977848 68355168 68472424 68582245 68582837 68737776 68906571 68912994 69169160 69434064 69477445 69532707 69707701 69723516 69848936

17 . . 6.75 . . 6.5 . . 16 . . 4 . . 7 . . 6 . . 4 . . 9.5 . . 3.25 . . 6.5 . . 10.3333 . . 3.83333 . . 5 . . 5 . . 5.25 . . 10.5 . . 3.83333 . . 6 . . 7 . . 10 . . 6.33333 . . 8 . . 5 . . 6.5 . . 3.5 . . 5.33333 . . 11 . . 4.5 . . 9 . . 5 . . 7.5 . . 3.75 . . 5 . . 5.75 . . 11.5 . . 5.75 . . 4.8 . . 8.75 . . 11.5 . . 4 . . 3.8 . . 5.5 . . 5.5 . . 6.66667 . . 7.75 . . 9 . . 4.25 . . 3.8 . . 4.2 . . 8 . . 6 . . 5 . . 4 . . 6.75 . . 5.5 . . 6.5 . . 4.33333 . . 6.25 . . 9 . . 11 . . 6.33333 . . 5.5 . . 3.75 . . 6.5 . . 6.75 . . 3.16667 . . 10.5 . . 6 . . 14.5 . . 4.75 . . 7.5 . . 6.5 . . 4.6 . . 5.5 . . 5.8 . . 5.5 . . 3.5 . . 7.25 . . 7.5 . . 4.25 . . 6 ENSSSCT00000010405 DCT 5.5 . . 6.75 ENSSSCT00000010408 GPR180

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intron

0.196 -0.113 0.08 . -0.151 . -0.192 . . . . 0.075 . . . 0.046 . . -0.093 -0.043 -0.405 -0.045 -0.013 -0.001 -0.119 0.202 0.14 . . -0.064 -0.014 0.004 . . -0.167 -0.124 . . -0.227 0.262 -0.169 -0.206 . -0.277 0.06 . 1.02 0.052 0.101 0.138 0.124 . . . -0.273 0.256 0.086 -0.039 0.186 -0.028 0.22 . -0.176 -0.152 . -0.429 -0.345 . 0.012 . -0.202 0.278 -0.074 0.186 -0.008 0.448 0.126 . 0.046 0.001 0.281 -0.255 -0.002 0.241

814409 rs7877 rs789532993 . 856959 rs7925 rs791184979 rs691559367 rs786845773 rs788360019 030628 rs7903 rs788779542 rs789374600 353318 rs7908 . . rs788778989 497159 rs7934 rs789108428 265274 rs7924 rs789915760 rs786947221 694753 rs7896 rs789375038 269140 rs7935 rs793124347 . rs786219681 925893 rs7926 rs791102912 . 013196 rs7896 . . . . rs793389302 324493 rs7913 rs788934121 925198 rs7916 rs709452796 rs704841174 603776 rs7875 742676 rs7866 rs786941530 432501 rs7930 . . rs788201781 rs791444215 585114 rs7926 812239 rs7932 rs791642038 413773 rs7929 rs790976266 rs787815930 651977 rs7881 rs786529796 . rs793801072 rs793716412 rs791316118 . . 997547 rs7882 . . rs791567489 . rs789948154 rs786492754 . 411436 rs7867 694360 rs7884 . rs787296748 rs707645564 rs789001271 . rs786651440 rs790327218 614870 rs7882 rs791247442 rs792256572 rs791912599 rs787185847

2 2 3 4 2 4 4 3 2 2 2 2 2 2 3 2 2 2 3 2 2 3 3 2 4 2 2 2 2 3 2 4 2 3 2 3 2 2 2 5 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 3 2 2 2 3 2 2 2 2 2 2 2 2 3 2 3 2 2 2 2 3 2 2 2 3

AC.GT AG.CT AAAAT.ATTTT AAAAAG.CTTTTT AG.CT AAAC.GTTT AT.AT AAC.GTT AC.GT AAAAT.ATTTT AC.GT AAC.GTT AAAC.GTTT AG.CT AAAT.ATTT AAT.ATT AAT.ATT AAC.GTT AT.AT AGC.GCT AAAC.GTTT AAAT.ATTT AC.GT AAACC.GGTTT AC.GT AG.CT AAAT.ATTT AAAC.GTTT AC.GT AAC.GTT AAT.ATT AC.GT AAAG.CTTT AC.GT AAAT.ATTT AC.GT AC.GT AC.GT AAAAAT.ATTTTT AAAC.GTTT AG.CT AC.GT AAAC.GTTT AATG.CATT AC.GT AC.GT AC.GT AAC.GTT AATG.CATT AAAAC.GTTTT AG.CT AAG.CTT AAAAAC.GTTTTT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AT.AT AT.AT AAAAC.GTTTT AAAG.CTTT ACAT.ATGT AAAG.CTTT ATC.GAT AAAT.ATTT AAAG.CTTT AAG.CTT AAAC.GTTT AAT.ATT AAAAAC.GTTTTT AG.CT AC.GT AAAC.GTTT AAAG.CTTT AAC.GTT AG.CT AAAC.GTTT AAAG.CTTT AT.AT AT.AT AAC.GTT AT.AT AC.GT AG.CT AAC.GTT

11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11

69869604 69941011 70175986 70314269 70521523 70529195 70541994 71917759 72017533 72139752 72314489 72320921 72322321 72768891 72774616 72814559 72905260 72989873 72994098 73193202 73527940 73770058 73933915 73989425 74021094 74212264 74221469 74230730 75208489 75314389 75377074 75390494 75895940 75953709 76143429 76231063 76308780 76381404 76816230 76919733 77175607 77242977 77251967 77445298 77625537 77632003 77724250 77758256 77761670 77901503 78231661 78299348 78313038 78331377 78420040 78420040 78484023 78484023 78519624 78524238 78674647 78689232 79181897 79206302 79218586 79701328 79706393 79790607 79812053 79813009 79851296 79916107 79938641 79952384 80232406 80542937 80605644 80620465 81012620 81237191 81333534 81361726 81380623 81498183

69869616 69941025 70176005 70314289 70521534 70529217 70542005 71917780 72017543 72139778 72314500 72320935 72322344 72768902 72774635 72814572 72905271 72989893 72994113 73193219 73527961 73770075 73933927 73989448 74021103 74212284 74221486 74230743 75208505 75314401 75377086 75390505 75895961 75953720 76143448 76231072 76308794 76381414 76816248 76919751 77175616 77242987 77251981 77445313 77625547 77632012 77724261 77758269 77761695 77901519 78231671 78299362 78313059 78331394 78420067 78420067 78484032 78484032 78519648 78524252 78674661 78689255 79181910 79206318 79218598 79701340 79706430 79790622 79812072 79813018 79851322 79916127 79938664 79952405 80232423 80542959 80605668 80620476 81012631 81237206 81333558 81361737 81380637 81498195

6.5 7.5 4 3.5 6 5.75 6 7.33333 5.5 5.4 6 5 6 6 5 4.66667 4 7 8 6 5.5 4.5 6.5 4.8 5 10.5 4.5 3.5 8.5 4.33333 4.33333 6 5.5 6 5 5 7.5 5.5 3.16667 4.75 5 5.5 3.75 4 5.5 5 6 4.66667 6.5 3.4 5.5 5 3.66667 3.6 7 7 5 5 5 3.75 3.75 6 4.66667 4.25 3.25 4.33333 9.5 5.33333 3.33333 5 13.5 5.25 6 7.33333 9 5.75 6.25 6 6 5.33333 12.5 6 7.5 4.33333

ENSSSCT00000010407 TGDS intron . . intergenic ENSSSCT00000032528 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000010418 DZIP1 intron ENSSSCT00000026790 DNAJC3 intron ENSSSCT00000010419 . intron ENSSSCT00000010419 . intron ENSSSCT00000010419 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000010422 MBNL2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000010434 UBAC2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000010440 . intron . . intergenic . . intergenic ENSSSCT00000024376 . intron . . intergenic . . intergenic ENSSSCT00000010444 ITGBL1 intron ENSSSCT00000010445 FGF14 intron ENSSSCT00000010445 FGF14 intron ENSSSCT00000010445 FGF14 intron ENSSSCT00000010445 FGF14 intron ENSSSCT00000010445 FGF14 intron . . intergenic . . intergenic ENSSSCT00000010446 . intron ENSSSCT00000010446 . intron ENSSSCT00000010447 . intron ENSSSCT00000026999 . intron ENSSSCT00000010450 . intron ENSSSCT00000026999 . intron ENSSSCT00000010450 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

-0.098 0.044 . 0.016 . . . 0.045 -0.144 . -0.111 0.187 0.275 0.478 -0.14 0.352 0.323 -0.123 0.007 0.309 0.187 0.301 0.224 0.188 0.246 . -0.107 0.172 0.109 0.074 0.092 -0.037 0.051 0.062 . . -0.094 0.056 0.233 -0.17 . 0.056 0.033 0.105 0.027 -0.006 0.005 . -0.128 0.069 -0.07 0.021 -0.265 -0.025 0.061 0.061 . . -0.099 -0.318 . . -0.025 0.056 0.055 -0.183 0.151 . . -0.098 . -0.369 -0.619 0.275 -0.21 -0.199 0.082 0.8 . 0.615 -0.136 -0.01 -0.035 -0.189

rs792281924 113412 rs7877 rs789342337 . rs791325381 751623 rs7881 571644 rs7892 869937 rs7881 rs788837795 rs787696529 . rs786503617 561972 rs7927 rs786439971 . . . 526151 rs7883 . rs792296959 895830 rs7872 rs791595196 539533 rs7931 . . . rs791219053 231748 rs7890 577462 rs7874 rs793870879 rs710583847 rs786385243 251452 rs7928 898311 rs7913 rs791827958 . . 029591 rs7899 . 769905 rs7877 rs792511496 . rs793818437 rs786896676 . . . 627079 rs7926 236497 rs7897 rs790677206 . rs790753732 rs793834621 rs788387988 rs786275002 rs786275002 rs789775285 rs789775285 rs788555922 394180 rs7894 rs790923508 . 301607 rs7889 rs790383575 305972 rs7889 rs792633361 752879 rs7901 . rs792631240 rs789993801 rs788489213 rs787942919 rs786544994 389220 rs7873 rs791976986 rs792340603 934138 rs7917 rs786793877 rs789475347 . rs696997454 rs787971803 rs793520924 .

2 3 2 2 2 2 2 2 2 3 2 2 2 2 2 3 2 2 2 2 2 2 3 2 3 2 2 2 2 2 2 2 2 2 2 4 2 3 2 2 2 4 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 4 2 2 3 4 2 2 4 4 2 2 2 2 2

AAC.GTT AG.CT AC.GT AAAC.GTTT AAAT.ATTT AC.GT AT.AT AC.GT AG.CT AC.GT AC.GT AC.GT AAAT.ATTT AC.GT AGGC.GCCT AACCCT.AGGGT AC.GT AAAC.GTTT AAAC.GTTT AC.GT AC.GT AC.GT AAAT.ATTT AAAT.ATTT AT.AT AG.CT AC.GT AG.CT AAAG.CTTT AC.GT AAAAC.GTTTT AC.GT AAAG.CTTT AG.CT AAAT.ATTT AC.GT AAAG.CTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AC.GT AAC.GTT AG.CT AAAT.ATTT AAC.GTT ACAG.CTGT AATG.CATT AAAC.GTTT AG.CT AAG.CTT AAAAG.CTTTT AC.GT AAAAC.GTTTT AG.CT AAAC.GTTT AAAAAC.GTTTTT AC.GT AC.GT AGG.CCT AC.GT AAAT.ATTT AAAC.GTTT AC.GT AAC.GTT AG.CT AG.CT AAAC.GTTT AAAG.CTTT AG.CT AAAT.ATTT AC.GT AC.GT AC.GT AAAT.ATTT AAAT.ATTT AC.GT AAC.GTT AAGG.CCTT AAAC.GTTT AG.CT AAAAC.GTTTT AT.AT AAAC.GTTT AAAC.GTTT

11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12

81554787 81725018 81977432 82306410 82429193 82879037 82998551 83238529 83478416 83536413 84377604 84508348 84714694 84757422 86485271 86616589 86734704 87143341 379850 777100 1234609 1234609 1490750 1490750 2494898 2606583 3694988 3770214 4614506 4627442 4768423 4770636 5070979 5134357 5409776 5501731 5552484 5676979 5676979 5676979 6241924 7032192 7787417 7984803 8385690 8393053 8393725 8482615 8814490 8977494 9087997 9229715 9436628 9542873 9774590 9827241 10204451 10244368 10369330 10391354 10443746 10482611 10730599 10754794 10816149 10910990 10936176 10957759 10969663 11116567 11149616 11193889 11193889 11204602 11204602 11246306 11268388 11372101 11654947 11904317 11935854 12019960 12109421 12187916

81554800 81725030 81977441 82306430 82429213 82879047 82998561 83238551 83478436 83536427 84377614 84508359 84714706 84757432 86485289 86616607 86734719 87143355 379866 777111 1234636 1234636 1490764 1490764 2494913 2606592 3694999 3770224 4614525 4627453 4768444 4770645 5070992 5134367 5409798 5501745 5552506 5676994 5676994 5676994 6241936 7032206 7787437 7984821 8385712 8393071 8393740 8482634 8814516 8977513 9088035 9229729 9436645 9542882 9774605 9827260 10204462 10244386 10369359 10391364 10443764 10482638 10730609 10754817 10816161 10911004 10936194 10957771 10969674 11116584 11149632 11193901 11193901 11204617 11204617 11246320 11268405 11372122 11654963 11904333 11935868 12019969 12109439 12187932

4.66667 6.5 5 5.25 5.25 5.5 5.5 11.5 10.5 7.5 5.5 6 3.25 5.5 4.75 3.16667 8 3.75 4.25 6 14 14 3.75 3.75 8 5 6 5.5 5 6 4.4 5 3.5 5.5 5.75 7.5 5.75 4 4 4 6.5 5 10.5 4.75 7.66667 4.75 4 5 13.5 6.66667 7.8 7.5 3.6 5 4 3.33333 6 9.5 10 5.5 4.75 7 5.5 8 6.5 7.5 4.75 3.25 6 4.5 8.5 6.5 6.5 4 4 7.5 6 5.5 4.25 8.5 3 5 4.75 4.25

. . . . . . . . ENSSSCT00000010461 ENSSSCT00000010461 ENSSSCT00000010462 . . ENSSSCT00000029690 . ENSSSCT00000010486 ENSSSCT00000010488 . ENSSSCT00000018654 . ENSSSCT00000027597 ENSSSCT00000023942 ENSSSCT00000023391 ENSSSCT00000018660 ENSSSCT00000018683 . . . . ENSSSCT00000022358 . . ENSSSCT00000018709 ENSSSCT00000018711 . . ENSSSCT00000018726 ENSSSCT00000018730 ENSSSCT00000023832 ENSSSCT00000025315 ENSSSCT00000018742 . ENSSSCT00000018773 . ENSSSCT00000018779 ENSSSCT00000018779 ENSSSCT00000018779 . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000035633 ENSSSCT00000034463 ENSSSCT00000018783 ENSSSCT00000034463 ENSSSCT00000018783 ENSSSCT00000018783 . . . . . . ENSSSCT00000018787 ENSSSCT00000018789

. . . . . . . . MYO16 MYO16 COL4A1 . . . . GAS6 RASA3 . TBCD . . . AATK AATK TBC1D16 . . . . MFSD11 . . PRPSAP1 RNF157 . . UNK SAP30BP SAP30BP RECQL5 KCTD2 . SDK2 . SLC39A11 SLC39A11 SLC39A11 . . . . . . . . . . . . . . . . . . . . . . . MKK6 MKK6 MKK6 MKK6 MKK6 MKK6 . . . . . . FAM20A WIPI1

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intron intergenic promoter intron intergenic intron intergenic intron intron intron intron intron intergenic intergenic intergenic intergenic 3'utr intergenic intergenic intron intron intergenic intergenic intron intron intron promoter intron intergenic intron intergenic intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic promoter intron

-0.404 . -0.452 -0.068 . -0.236 . 0.119 0.405 0.093 -0.273 -0.161 . . -0.053 -0.024 -0.351 . . . -0.446 -0.446 -0.084 -0.084 -0.026 -0.073 0.088 -0.252 . 0.046 . . . -0.123 . . -0.09 0.625 0.625 0.625 -0.235 . -0.265 . . -0.224 0.196 . -0.092 -0.075 -0.05 0.519 -0.181 -0.143 0.11 -0.022 -0.167 0.073 -0.325 -0.206 0.416 -0.08 -0.106 -0.067 0.055 0.208 0.304 -0.146 0.05 -0.136 0.242 . . 0.206 0.206 0.233 0.141 0.1 0.099 -0.156 . . -0.046 0.125

rs790140784 rs792236205 rs789656395 rs789788399 100140 rs7873 rs792923445 rs790896202 315591 rs7880 383154 rs7877 rs793463374 . 286132 rs7879 . rs791770753 rs788141475 428578 rs7913 . 662958 rs7915 rs787646222 . 758095 rs7885 758095 rs7885 210732 rs7882 210732 rs7882 . rs789782727 . . rs788589848 . rs791456632 rs791608894 rs788340760 . rs790076277 897295 rs7927 rs791163156 rs790962948 rs790962948 rs790962948 rs788603062 463279 rs7899 341615 rs7903 830541 rs7921 722006 rs7938 245741 rs7887 . 763786 rs7864 rs788320892 rs786527230 892071 rs7903 rs789675738 185345 rs7902 . 215024 rs7922 700848 rs7928 rs791002237 . . . 738438 rs7906 rs786331727 . rs792444481 . . rs787097161 877431 rs7895 . rs789572496 rs787496064 rs789825134 rs789825134 rs791367607 rs791367607 983186 rs7893 365557 rs7925 821510 rs7865 rs792430399 129982 rs7917 rs792207455 rs791888597 rs788746754 rs792690484

2 2 2 4 2 2 3 2 2 2 3 2 2 3 2 2 2 3 2 2 2 2 2 2 4 2 4 2 2 3 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 3 2 2 2 2 2 3 2 2 3 2 2 4 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2

AAAC.GTTT AAAT.ATTT AT.AT AT.AT AAAC.GTTT AC.GT AT.AT AC.GT AC.GT AAC.GTT AT.AT AAATG.CATTT AAAAAC.GTTTTT AT.AT AAAT.ATTT AAAG.CTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AT.AT AC.GT AAAAC.GTTTT AAAAC.GTTTT AAAAAC.GTTTTT AAGGAG.CTCCT AAAAAG.CTTTTT AG.CT AAAG.CTTT AAAT.ATTT AAAAC.GTTTT AAAC.GTTT AC.GT AG.CT AC.GT AAAAC.GTTTT AAAG.CTTT AAAG.CTTT AAC.GTT AAAC.GTTT AAAG.CTTT AAC.GTT AAC.GTT AC.GT AT.AT AAAAC.GTTTT AAAC.GTTT AC.GT AG.CT AAC.GTT AC.GT AAAT.ATTT ACACTC.GAGTG AAAC.GTTT AAAT.ATTT AAAG.CTTT AG.CT AG.CT AC.GT AAAC.GTTT AC.GT AG.CT AAAT.ATTT AC.GT AC.GT AT.AT AC.GT AAAG.CTTT AAAG.CTTT AG.CT AAAAT.ATTTT AC.GT AAAT.ATTT AAAT.ATTT AT.AT AC.GT AAC.GTT AAC.GTT AAAT.ATTT AC.GT AC.GT AAAT.ATTT AG.CT AAC.GTT

12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12

12415914 12838802 12873323 12989539 12990761 13042016 13048999 13137379 13437776 13526697 13896725 14012826 14112774 14165378 14184560 14228023 14262647 14356137 14464199 14511937 14593979 14837796 15353089 15353089 15467426 15475025 15492197 15583684 15714029 15890017 16066096 16160606 16221175 16370338 16435610 16472177 16703915 16703915 16714611 16780068 16791109 16852963 17098964 17275518 17487094 17520958 18182019 18477473 18735329 18991927 19492272 19536391 19581046 19995727 20074109 20163618 20283177 20516644 21303649 21721872 21964569 21977051 22041665 22137031 22231850 22305306 22402562 22536644 22699744 22825786 22828490 22865212 22914198 22914198 22950810 23133618 23194643 23258603 23385555 24267147 24640470 24656615 24709947 24932985

12415928 12838834 12873334 12989548 12990787 13042045 13049009 13137391 13437787 13526737 13896736 14012844 14112795 14165387 14184578 14228046 14262671 14356153 14464211 14511961 14593992 14837806 15353111 15353111 15467453 15475045 15492221 15583698 15714055 15890045 16066124 16160621 16221187 16370348 16435621 16472205 16703938 16703938 16714631 16780086 16791123 16852976 17098981 17275529 17487105 17520980 18182031 18477487 18735339 18991949 19492284 19536407 19581066 19995749 20074126 20163662 20283186 20516653 21303663 21721893 21964579 21977068 22041696 22137041 22231868 22305318 22402579 22536676 22699763 22825798 22828509 22865226 22914215 22914215 22950828 23133637 23194658 23258616 23385576 24267170 24640486 24656637 24709956 24933000

3.75 8.25 6 5 6.75 15 5.5 6.5 6 13.6667 6 3.8 3.66667 5 4.75 6 6.25 4.25 3.25 5 7 5.5 4.6 4.6 4.66667 3.5 4.16667 7.5 6.75 7.25 5.8 4 6.5 5.5 6 5.8 6 6 7 4.75 3.75 4.66667 6 6 6 4.6 3.25 7.5 5.5 7.66667 6.5 4.25 3.5 5.75 4.5 11.25 5 5 7.5 5.5 5.5 9 8 5.5 9.5 6.5 9 8.25 5 6.5 4 7.5 4.5 4.5 9.5 10 5.33333 4.66667 5.5 12 8.5 5.75 5 5.33333

ENSSSCT00000018792 ENSSSCT00000018795 ENSSSCT00000018795 . . ENSSSCT00000027357 ENSSSCT00000027357 . . ENSSSCT00000018798 ENSSSCT00000018802 ENSSSCT00000018802 ENSSSCT00000018804 ENSSSCT00000018804 ENSSSCT00000018804 ENSSSCT00000018804 ENSSSCT00000018804 ENSSSCT00000018804 . . . ENSSSCT00000018810 ENSSSCT00000018827 ENSSSCT00000029983 ENSSSCT00000018832 ENSSSCT00000018832 ENSSSCT00000018832 ENSSSCT00000018832 . . ENSSSCT00000018837 ENSSSCT00000018840 . . . . ENSSSCT00000027689 ENSSSCT00000018841 . . . ENSSSCT00000018844 ENSSSCT00000018846 . . . ENSSSCT00000018861 . ENSSSCT00000018882 . . ENSSSCT00000018911 ENSSSCT00000024088 . ENSSSCT00000025436 . ENSSSCT00000018927 ENSSSCT00000018941 . . . . . . . . . . . ENSSSCT00000019043 ENSSSCT00000019043 . ENSSSCT00000019046 ENSSSCT00000025164 ENSSSCT00000019047 . . ENSSSCT00000019057 ENSSSCT00000019059 . . . . .

GNA13 intron . intron . intron . intergenic . intergenic . intron . intron . intergenic . intergenic PRKCA intron HELZ intron HELZ intron PITPNC1 intron PITPNC1 intron PITPNC1 intron PITPNC1 intron PITPNC1 intron PITPNC1 intron . intergenic . intergenic . intergenic TEX2 intron KCNH6 intron KCNH6 intron TANC2 intron TANC2 intron TANC2 intron TANC2 intron . intergenic . intergenic TLK2 intron EFCAB3 intron . intergenic . intergenic . intergenic . intergenic EFCAB13 promoter EFCAB13 promoter . intergenic . intergenic . intergenic CDC27 intron KANSL1 intron . intergenic . intergenic . intergenic PLEKHM1 intron . intergenic EFTUD2 intron . intergenic . intergenic MPP3 intron DUSP3 3'utr . intergenic PIGBRCA1 intron . intergenic WNK4 intron . intron . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intron . intron . intergenic ZPBP2 intron ZPBP2 intron IKZF3 intron . intergenic . intergenic CDK12 intron FBXL20 intron . intergenic . intergenic . intergenic . intergenic . intergenic

. 0.2 . . . 0.344 -0.513 . -0.02 -0.089 . . 0.071 0.276 0.036 . -0.113 . . 0.16 . 0.039 -0.19 -0.19 2.397 . 0.257 0.096 . 0.066 -0.464 0.881 . . . . 0.528 0.528 0.049 0.154 0.652 0.281 0.076 . . . 0.143 0.218 1.442 . -0.11 -0.565 0.004 . 0.282 . 1.741 -0.011 -0.731 . . 0.149 -0.092 0.223 0 -0.021 0.335 0.114 0.084 0.809 0.768 0.34 . . . 0.175 0.2 2.584 0.025 0.151 0.198 0.386 0.341 -0.141

. . 506061 rs7879 rs787370227 622623 rs7938 . 946841 rs7863 . rs789466189 rs792679305 858151 rs7904 rs786988064 . . rs789941461 795966 rs7896 rs786336558 rs790438582 952708 rs7896 525604 rs7922 rs793837668 . rs793853612 rs793853612 rs790996112 . 936077 rs7879 . rs787008094 rs789286792 rs787564705 rs786826650 rs789299486 rs787371421 rs792081110 rs789052850 rs790237671 rs790237671 rs786740483 785182 rs7892 rs791701690 rs789868521 rs792698204 345493 rs7862 766269 rs7937 . rs788009974 rs791298802 rs790573875 rs787891582 rs788628203 rs793050085 rs792613631 rs792697774 rs788880834 rs790885245 . rs787196663 . rs696776831 rs788827895 rs786324393 rs791118502 rs786777208 rs791826496 rs788671773 590455 rs7877 rs787144341 rs791737909 . rs788203953 rs788052736 . . . rs789224789 rs790545834 rs790879186 rs791007275 254262 rs7889 rs790325760 rs793742545 rs789729137 rs789750965

2 2 4 2 2 2 2 2 2 2 2 2 2 4 2 3 2 3 2 3 2 2 2 2 2 3 2 2 2 2 2 2 3 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 4 2 4 2 2 2 4 2 2 2 2 2 2 2 2

AC.GT AC.GT AC.GT AAAAC.GTTTT AAAT.ATTT AT.AT AGG.CCT AC.GT AAAAT.ATTTT AC.GT AG.CT AT.AT AAATG.CATTT AAC.GTT AC.GT AG.CT AAAAAC.GTTTTT AT.AT AG.CT AT.AT AG.CT AAAC.GTTT AAAC.GTTT AAG.CTT AG.CT AAC.GTT AC.GT AAC.GTT AT.AT AATG.CATT AC.GT AT.AT AT.AT AT.AT AT.AT AAG.CTT AAG.CTT AAAC.GTTT AAAC.GTTT AC.GT AAAAC.GTTTT AAG.CTT AAAAAT.ATTTTT AATG.CATT AAT.ATT AAG.CTT AC.GT AC.GT AAAT.ATTT AGG.CCT AAAC.GTTT AC.GT AAGC.GCTT AT.AT AT.AT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAT.ATTT AAAC.GTTT AAAAC.GTTTT AAGC.GCTT AAAT.ATTT AAC.GTT AAATT.AATTT AAAAG.CTTTT AT.AT AAAAG.CTTTT AAC.GTT AT.AT AT.AT AT.AT AAAC.GTTT AG.CT AAT.ATT AAAAC.GTTTT AAC.GTT AG.CT AC.GT AAC.GTT AAAT.ATTT AT.AT

12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12

25144760 25186685 25796529 25831965 25967341 25984950 26067776 27185680 27194261 27527051 27860823 28230612 28258058 28460147 28466762 28493260 28506123 28537583 28631466 28638193 28693427 29249064 29250638 29608147 29684077 30203681 30765123 30872794 31140567 31228906 31591223 31696961 31696961 31704792 31704792 31713654 31713654 32180681 32322834 32514008 32598156 32618212 32693149 33227193 33295024 33499875 33945689 34001817 34112515 34703358 35029108 35386959 35840318 35881938 35881938 36028941 36028941 36545469 36545469 36684039 36687870 36725812 36742404 36934513 36938172 37055851 37164709 37316378 37331185 37361871 37592850 37707120 37707120 37742198 37996370 38451809 38487306 38538113 38539045 38559044 38575375 38582480 38653005 38677341

25144781 25186698 25796539 25831986 25967358 25984965 26067790 27185693 27194281 27527060 27860848 28230626 28258101 28460160 28466775 28493302 28506144 28537592 28631479 28638203 28693436 29249093 29250655 29608163 29684089 30203695 30765142 30872816 31140576 31228927 31591240 31696978 31696978 31704812 31704812 31713667 31713667 32180697 32322853 32514033 32598180 32618232 32693166 33227210 33295039 33499887 33945703 34001827 34112535 34703372 35029122 35386972 35840330 35881949 35881949 36028959 36028959 36545495 36545495 36684059 36687884 36725827 36742432 36934533 36938190 37055864 37164732 37316405 37331206 37361893 37592864 37707129 37707129 37742207 37996390 38451823 38487336 38538144 38539058 38559053 38575393 38582501 38653032 38677350

11 7 5.5 4.4 4.5 8 5 7 4.2 5 13 7.5 8.8 4.66667 7 21.5 3.66667 5 7 5.5 5 7.5 4.5 5.66667 6.5 5 10 7.66667 5 5.5 9 9 9 10.5 10.5 4.66667 4.66667 4.25 5 13 5 7 3 4.5 5.33333 4.33333 7.5 5.5 5.25 5 3.75 7 3.25 6 6 4.75 4.75 6.75 6.75 5.25 3.75 4 5.8 5.25 4.75 4.66667 4.8 5.6 11 4.6 5 5 5 5 5.25 7.5 10.3333 6.4 4.66667 5 9.5 7.33333 7 5

. ENSSSCT00000022825 . ENSSSCT00000030769 . ENSSSCT00000019107 . . . ENSSSCT00000019153 . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000019162 ENSSSCT00000031451 ENSSSCT00000019162 ENSSSCT00000031451 ENSSSCT00000019162 ENSSSCT00000031451 . . . . . . . . ENSSSCT00000019171 ENSSSCT00000034924 ENSSSCT00000019179 ENSSSCT00000019177 . . ENSSSCT00000027876 . ENSSSCT00000019208 ENSSSCT00000019209 ENSSSCT00000035676 ENSSSCT00000035025 ENSSSCT00000033129 ENSSSCT00000024586 . . . . ENSSSCT00000027408 ENSSSCT00000027408 ENSSSCT00000026532 . ENSSSCT00000019232 ENSSSCT00000019232 ENSSSCT00000019233 . ENSSSCT00000019236 ENSSSCT00000024721 ENSSSCT00000019238 . . . . . . . . ENSSSCT00000019240 ENSSSCT00000019240

. . . . . KAT7 . . . MBTD1 . . . . . . . . . . . . . . . . . . . . . TOM1L1 TOM1L1 TOM1L1 TOM1L1 TOM1L1 TOM1L1 . . . . . . . . ANKFN1 C17orf67 SCPEP1 DGKE . . DYNLL2 . TEX14 TEX14 4-Sep 4-Sep TRIM37 TRIM37 . . . . GDPD1 GDPD1 PRR11 . ssc-mir-21 ssc-mir-21 TUBD1 . MED13 MED13 . . . . . . . . . BCAS3 BCAS3

intergenic intron intergenic intron intergenic intron intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intergenic intergenic intron intergenic intron intron promoter promoter intron intron intergenic intergenic intergenic intergenic intron intron intron intergenic intron intron intron intergenic intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron

. . 0.511 0.233 0.296 0.333 0.012 . -0.154 0.08 . . . -0.082 0.839 -0.163 0.005 0.041 -0.117 0.007 . 0.018 0.146 . . . -0.171 -0.321 . -0.038 -0.035 0.908 0.908 0.069 0.069 . . 0.489 -0.158 0.069 . 0.053 . 0.07 0.065 . -0.227 0.783 -0.153 0.251 0.47 0.214 . 0.273 0.273 0.403 0.403 0.319 0.319 . 0.328 0.147 -0.038 . . 0.161 . 0.279 . . . . . 2.268 . . 0.263 0.226 0.105 1.567 -0.092 1.471 -0.065 0.146

989849 rs7884 . 748609 rs7929 rs786842842 rs790825254 rs789977908 rs791341717 857943 rs7895 rs788710853 036363 rs7884 rs790064443 559157 rs7871 519409 rs7924 153982 rs7910 rs790559473 . rs788485916 . rs789654058 rs793270913 . 697706 rs7871 rs787725711 rs701620606 rs789207399 . . 329748 rs7923 rs789612612 rs791181123 . rs792154637 rs792154637 . . rs789690233 rs789690233 rs788878701 rs791492486 rs792459905 rs701326797 rs712737905 rs786246456 rs706132842 rs791707497 rs786550046 649169 rs7936 413477 rs7871 rs790167855 rs790467068 rs787488879 . rs791503096 rs790322415 rs790322415 rs793729884 rs793729884 rs786418078 rs786418078 rs793141766 . 561001 rs7883 rs789014010 804215 rs7921 rs792667601 511715 rs7894 rs792732175 rs786524572 763270 rs7908 rs790157563 764395 rs7912 070560 rs7907 070560 rs7907 rs791722157 964869 rs7930 rs793578196 583077 rs7862 rs787509228 . rs791757850 rs792209293 rs793134338 rs789984582 rs792459785

2 4 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 4 2 4 3 2 2 2 2 4 2 3 2 3 2 2 4 4 2 2 2 2 2 2 2 2 2 4 2 3 3 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 4 2

AAAC.GTTT ACAT.ATGT AAAC.GTTT AT.AT AAAG.CTTT AGG.CCT AAAT.ATTT AAAAC.GTTTT AC.GT AATG.CATT AC.GT AGGC.GCCT AAAG.CTTT AAAC.GTTT AAT.ATT AAAC.GTTT AC.GT AG.CT AAAC.GTTT AC.GT AG.CT AAAT.ATTT AC.GT AGG.CCT AG.CT AAAAAG.CTTTTT AAAG.CTTT AAAAC.GTTTT AAAC.GTTT AAC.GTT AAAC.GTTT AAAAC.GTTTT AC.GT AAAT.ATTT ATC.GAT AC.GT AAAC.GTTT AG.CT AAAC.GTTT AT.AT AC.GT AAAC.GTTT AG.CT AC.GT AAAC.GTTT AT.AT AC.GT AG.CT AG.CT AT.AT AATC.GATT AAAC.GTTT AGG.CCT AC.GT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AGGGC.GCCCT AACC.GGTT AATG.CATT AATG.CATT AT.AT AT.AT AAAC.GTTT AAAC.GTTT AAAT.ATTT AAAT.ATTT AAAAAC.GTTTTT AAAG.CTTT AC.GT AT.AT AC.GT AAAT.ATTT AAAAAC.GTTTTT AAT.ATT AAAT.ATTT AAC.GTT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AC.GT AG.CT

12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12

38741107 38752023 38785982 38859892 39051837 39453175 39590462 39744686 39799779 39836954 39843919 39923448 39940428 40149335 40176921 40236718 40239266 40287688 40381313 40390180 40610670 40624183 40882274 41052856 41124840 41203480 41249894 41288610 41389243 41393894 41398945 41611702 41783363 41867355 42198817 42217457 42421066 42671223 42890016 43011533 43078544 43094947 43402482 43464270 43983327 44127207 44138270 44327467 44486173 44883637 44976045 44989176 45011709 45052019 45062633 45110917 45121283 45150048 45294222 45377650 45377650 45473082 45473082 45480355 45480355 45546826 45607586 46172195 46247574 46287149 46294405 46401794 46831894 47121489 47200394 47458769 47489387 47507605 47620086 47842712 47842712 47842712 48030886 48303667

38741133 38752053 38786003 38859907 39051857 39453205 39590476 39744700 39799789 39836974 39843944 39923464 39940441 40149358 40176941 40236732 40239277 40287698 40381329 40390192 40610679 40624204 40882288 41052868 41124852 41203502 41249909 41288628 41389274 41393908 41398957 41611719 41783377 41867377 42198828 42217477 42421083 42671232 42890042 43011544 43078567 43094963 43402500 43464309 43983339 44127217 44138298 44327477 44486185 44883652 44976065 44989193 45011746 45052029 45062649 45110933 45121314 45150063 45294241 45377672 45377672 45473093 45473093 45480391 45480391 45546839 45607601 46172214 46247599 46287171 46294415 46401803 46831906 47121522 47200410 47458787 47489400 47507635 47620101 47842734 47842734 47842734 48030899 48303677

6.75 7.75 5.5 8 5.25 10.3333 3.75 3 5.5 5.25 13 4.25 3.5 6 7 3.75 6 5.5 4.25 6.5 5 5.5 7.5 4.33333 6.5 3.83333 4 3.8 8 5 3.25 3.6 7.5 5.75 4 10.5 4.5 5 6.75 6 12 4.25 9.5 20 3.25 5.5 14.5 5.5 6.5 8 5.25 4.5 12.6667 5.5 3.4 4.25 8 3.2 5 5.75 5.75 6 6 9.25 9.25 3.5 4 3.33333 6.5 11.5 5.5 5 3.25 5.66667 5.66667 4.75 4.66667 6.2 4 5.75 5.75 5.75 7 5.5

ENSSSCT00000019240 BCAS3 intron ENSSSCT00000019240 BCAS3 intron ENSSSCT00000019240 BCAS3 intron ENSSSCT00000019240 BCAS3 intron . . intergenic . . intergenic ENSSSCT00000032517 ZNHIT3 promoter ENSSSCT00000019255 MRM1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000019257 AATF intron ENSSSCT00000019257 AATF intron ENSSSCT00000019259 ACACA intron ENSSSCT00000019259 ACACA intron ENSSSCT00000019259 ACACA intron . . intergenic . . intergenic ENSSSCT00000029194 DUSP14 intron ENSSSCT00000028499 SYNRG intron . . intergenic ENSSSCT00000019265 . promoter . . intergenic . . intergenic ENSSSCT00000019272 C17orf66 intron . . intergenic ENSSSCT00000019278 . intron ENSSSCT00000019278 . intron ENSSSCT00000019278 . intron . . intergenic ENSSSCT00000027932 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000019295 MYO1D intron ENSSSCT00000019295 MYO1D intron . . intergenic . . intergenic ENSSSCT00000019302 RHOT1 intron ENSSSCT00000019314 COPRS intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000019316 RAB11FIP4 intron ENSSSCT00000023079 NF1 intron ENSSSCT00000019317 NF1 intron ENSSSCT00000023079 NF1 intron ENSSSCT00000019317 NF1 intron ENSSSCT00000023079 NF1 intron ENSSSCT00000019317 NF1 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000030105 NLK intron ENSSSCT00000030105 NLK intron ENSSSCT00000030105 NLK intron ENSSSCT00000019329 SPAG5 intron ENSSSCT00000019351 PHF12 intron . . intergenic ENSSSCT00000019357 NUFIP2 promoter . . intergenic . . intergenic ENSSSCT00000019362 . intron ENSSSCT00000033840 SSH2 intron ENSSSCT00000019363 SSH2 intron ENSSSCT00000034147 SSH2 intron . . intergenic ENSSSCT00000019366 EFCAB5 intron

-0.102 0.161 . 0.184 . . -0.017 0.224 1.539 0.464 1.644 -0.023 . 1.132 0.174 1.698 0.272 0.642 . 0.159 . . 0.207 -0.202 . . 0.114 . 0.265 0.383 0.393 0.347 . 0.541 -0.127 0.409 -0.249 -0.132 0.169 . -0.158 0.41 0.112 0.174 -0.082 0.183 . . 0.384 0.142 0.204 -0.132 . 0.101 0.002 . 0.007 -0.121 -0.269 0.08 0.08 0.162 0.162 . . . . 0.667 0.227 0.309 0.33 . . 0.177 0.466 1.779 0.467 . . 1.882 1.882 1.882 0.29 0.416

827388 rs7909 117082 rs7870 rs788279875 rs790975632 rs789610886 . . 709855 rs7899 rs793104148 rs790317292 rs791084697 rs791517462 rs788954969 rs786900806 . 802047 rs7914 rs790869966 rs790746766 746257 rs7896 rs704531194 . . 828102 rs7910 rs792544423 rs791703721 rs791339384 rs788461490 rs792372491 rs792957057 036759 rs7926 rs787885580 rs786542148 . 371467 rs7889 . rs698586585 rs786992900 275417 rs7920 rs791350412 rs792905070 215089 rs7876 rs788078807 rs791162974 rs793463094 rs789967368 rs698222345 . rs791026089 rs793276948 rs788017689 907136 rs7927 rs792093192 rs696607077 rs786393542 rs792811989 411335 rs7904 rs787259524 321165 rs7895 rs793293142 rs787406297 rs787406297 . . rs791397445 rs791397445 988342 rs7925 rs786458511 535853 rs7881 rs788360378 497998 rs7926 . rs790209380 073846 rs7876 rs793198860 rs792511012 967108 rs7925 . 032058 rs7904 rs788409646 rs793172005 rs793172005 rs793172005 rs789635737 929311 rs7927

2 3 2 2 2 2 2 2 4 4 2 2 2 2 2 2 2 2 2 2 3 3 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 5 4 2 2 2 2 2 2 2 2 4 2 2 2 3 3 3 3 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2

ACC.GGT AAT.ATT AAT.ATT AC.GT AAAC.GTTT AAAT.ATTT AAAC.GTTT AC.GT AAAAC.GTTTT AAAC.GTTT AT.AT AAAG.CTTT AC.GT AG.CT AAC.GTT AAC.GTT AAAT.ATTT AC.GT AAG.CTT AC.GT AG.CT AGAT.ATCT AC.GT AT.AT AC.GT AC.GT AC.GT AG.CT AATT.AATT AC.GT AAAT.ATTT AC.GT AAAC.GTTT AAG.CTT AAG.CTT AAAG.CTTT AAC.GTT AAG.CTT AAT.ATT AC.GT AAAAT.ATTTT AAAAT.ATTTT AAAAC.GTTTT AAC.GTT AAAAC.GTTTT AG.CT AC.GT AGGG.CCCT AT.AT AATG.CATT AAAT.ATTT AAAAC.GTTTT AAC.GTT AC.GT AT.AT AC.GT AAATT.AATTT AAAC.GTTT AAC.GTT AAC.GTT AAC.GTT AAAC.GTTT AC.GT AG.CT AC.GT AT.AT AAACC.GGTTT AC.GT AAC.GTT ACC.GGT AAGG.CCTT AAAG.CTTT AAAAG.CTTTT AC.GT AC.GT AC.GT AAC.GTT AC.GT AAAC.GTTT AAC.GTT AAAG.CTTT AC.GT ACACTC.GAGTG AC.GT

12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 13 13 13 13 13

48435141 48675911 48675911 48866081 49295671 49431364 49964320 49988786 50055570 50151382 50181340 50312479 50380701 50500538 50544675 50544675 50622498 50833317 50904772 51061205 51261121 51284642 51345393 51489369 51495388 51807567 51807567 51974585 52025159 52255639 52298112 52432100 52533567 52917085 53316721 53432543 53540751 53747620 53946738 54066487 54642280 55927165 56530287 56541639 56693943 57044577 57247691 57251861 57358858 57572655 57636117 57936488 58025266 58622338 58651517 58922908 59135178 59141572 59154545 59243575 59363735 59598949 59648689 60441140 60473048 60535724 60804993 60824865 61567027 61617124 61764919 61993853 62134942 62457880 62532845 62725893 62925204 63083567 63428133 39146 105570 500072 518521 599873

48435152 48675939 48675939 48866121 49295690 49431377 49964337 49988803 50055591 50151396 50181352 50312503 50380716 50500548 50544691 50544691 50622521 50833333 50904783 51061225 51261136 51284682 51345404 51489379 51495397 51807580 51807580 51974599 52025178 52255650 52298126 52432113 52533587 52917099 53316738 53432557 53540767 53747632 53946755 54066501 54642296 55927180 56530305 56541651 56693962 57044596 57247708 57251874 57358876 57572683 57636130 57936507 58025284 58622350 58651527 58922922 59135192 59141590 59154567 59243592 59363746 59598979 59648699 60441153 60473068 60535734 60805014 60824888 61567051 61617140 61764937 61993867 62134963 62457897 62532873 62725911 62925218 63083583 63428150 39170 105584 500086 518549 599890

4 9.66667 9.66667 20.5 5 3.5 4.5 9 4.4 3.75 6.5 6.25 8 5.5 5.66667 5.66667 6 8.5 4 10.5 8 10.25 6 5.5 5 7 7 7.5 5 6 3.75 7 5.25 5 6 3.75 5.66667 4.33333 6 7.5 3.4 3.2 3.8 4.33333 4 10 9 3.5 9.5 7.25 3.5 4 6.33333 6.5 5.5 7.5 3 4.75 7.66667 6 4 7.75 5.5 7 10.5 5.5 4.4 12 8.33333 5.66667 4.75 3.75 4.4 9 14.5 9.5 5 8.5 4.5 8.33333 3.75 7.5 4.83333 9

ENSSSCT00000019366 EFCAB5 intron ENSSSCT00000036665 GOSR1 intron ENSSSCT00000030283 GOSR1 intron . . intergenic . . intergenic ENSSSCT00000019386 VPS53 intron . . intergenic . . intergenic ENSSSCT00000019401 SMG6 intron ENSSSCT00000019401 SMG6 intron ENSSSCT00000019401 SMG6 intron ENSSSCT00000019407 . intron . . intergenic ENSSSCT00000019411 PAFAH1B1 intron ENSSSCT00000019409 . intron ENSSSCT00000025005 . intron . . intergenic ENSSSCT00000019412 RAP1GAP2 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000019432 OR1K1 promoter . . intergenic ENSSSCT00000019437 ASPA intron . . intergenic ENSSSCT00000035080 ITGAE intron ENSSSCT00000034272 ITGAE intron . . intergenic . . intergenic ENSSSCT00000019455 UBE2G1 intron . . intergenic ENSSSCT00000019457 SPNS3 intron ENSSSCT00000019461 TEKT1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000027166 CTC1 promoter . . intergenic . . intergenic ENSSSCT00000019577 PIK3R6 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000019584 USP43 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000031516 . intron ENSSSCT00000031516 . intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000019610 . intron ENSSSCT00000019611 MAP2K4 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000019634 NCOR1 intron ENSSSCT00000019634 NCOR1 intron ENSSSCT00000019641 SLC47A1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000029249 . intron . . intergenic ENSSSCT00000033415 CPNE4 intron

0.237 0.32 0.32 0.123 . -0.122 0.089 0.251 0.198 0.25 0.228 0.234 . 1.283 . . -0.085 1.372 . . -0.088 0.161 0.021 1.886 0.612 -0.085 -0.085 -0.067 . . -0.033 -0.251 . -0.083 . . 0.338 . . -0.029 0.006 0.211 0.383 -0.105 0.115 -0.049 0.536 0.124 -0.123 -0.233 -0.237 -0.081 . -0.165 0.234 -0.307 0.161 . 1.098 0.216 0.265 0.081 . 0.027 -0.159 0.093 -0.095 -0.025 0.046 -0.244 -0.058 . . -0.082 -0.114 . . . 0.004 . . . 0.215 0.295

rs790684128 485348 rs7905 485348 rs7905 137784 rs7891 rs793286927 rs792616556 rs790891720 862981 rs7905 rs791273615 . rs789830421 rs789489416 rs786288043 . rs787401046 rs787401046 420283 rs7933 334682 rs7901 rs788884371 rs712730120 675180 rs7896 rs710759770 rs791672849 239033 rs7898 rs790218254 893147 rs7896 893147 rs7896 . . 946679 rs7883 369347 rs7897 . rs788102791 rs788256184 rs791135501 rs791605492 rs789979757 rs789051959 rs788622937 469178 rs7884 rs790632275 rs789506559 rs791171316 rs792689631 141153 rs7893 609108 rs7913 155983 rs7882 rs789857361 893808 rs7872 rs786740873 rs791938622 . rs792865829 rs790830628 . rs789141193 rs792503636 235694 rs7904 615865 rs7874 902789 rs7884 rs793334950 581924 rs7908 617766 rs7890 rs792830425 rs791730749 rs789907191 rs787746681 907293 rs7903 . rs788355862 626002 rs7897 rs792563320 rs788670008 . . . rs788281346 794969 rs7885 rs790542815 rs790008254 rs790254515 rs792810317 943350 rs7900 .

2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 3 2 3 2 2 2 2 4 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 3 2 2 4

AC.GT AAAT.ATTT AAAAAC.GTTTTT AT.AT AG.CT AG.CT AG.CT AAAC.GTTT AT.AT AAAT.ATTT AC.GT AG.CT AAAT.ATTT AAAAT.ATTTT AAAC.GTTT AAAT.ATTT AAAC.GTTT AAAC.GTTT AAAAG.CTTTT AAAAC.GTTTT AT.AT AATT.AATT AAAT.ATTT AC.GT AAAAC.GTTTT AAAC.GTTT AAAAAT.ATTTTT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AAAAT.ATTTT AAAG.CTTT AC.GT AT.AT AAT.ATT AAAT.ATTT AC.GT AT.AT AAAT.ATTT AC.GT AG.CT AC.GT AT.AT AT.AT AAAC.GTTT AG.CT AAAC.GTTT AT.AT AAAT.ATTT AAT.ATT AC.GT ATC.GAT AG.CT AC.GT AC.GT AC.GT AAAC.GTTT AG.CT ACAG.CTGT AC.GT AAAT.ATTT AT.AT AG.CT AC.GT AAAAC.GTTTT AT.AT AAC.GTT AG.CT AG.CT AC.GT AT.AT AAC.GTT AAAAC.GTTTT AC.GT AAAC.GTTT AAC.GTT AC.GT AAAC.GTTT AATG.CATT AAAT.ATTT AAT.ATT

13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13

599873 820512 1129743 1203798 1258937 1314683 1379723 1551721 1844201 1859405 1873879 1885079 2040367 2461221 2559642 3120540 3139849 3147930 3168080 3263899 3266147 3309997 3360831 3681161 3884788 4222431 4350184 4614734 4614734 4709792 4709792 4767890 4767890 5102173 5507943 5785976 5808278 5909329 6047996 6148248 6544587 6603564 6691988 6783130 6894184 7122707 7159836 7370956 7373920 7446351 7469347 7737381 7754691 7758740 8010418 8033940 8140578 8328347 8933057 8933920 8935884 8961621 9081598 9210172 9443173 9475381 9724766 9857103 9874269 9890559 10027194 10037041 10098806 10292816 10308360 10337845 10452923 10582141 10714072 10811241 11049814 11164218 11225614 11247484

599890 820530 1129773 1203810 1258947 1314702 1379732 1551734 1844231 1859420 1873891 1885093 2040386 2461252 2559655 3120554 3139895 3147947 3168098 3263921 3266157 3310011 3360846 3681171 3884808 4222453 4350204 4614748 4614748 4709812 4709812 4767911 4767911 5102188 5507959 5786008 5808288 5909344 6048010 6148263 6544615 6603581 6692000 6783139 6894198 7122716 7159854 7370970 7373929 7446363 7469373 7737398 7754703 7758751 8010432 8033950 8140587 8328357 8933066 8933938 8935899 8961637 9081608 9210196 9443183 9475395 9724776 9857123 9874289 9890577 10027204 10037057 10098833 10292826 10308379 10337861 10452935 10582159 10714088 10811253 11049832 11164246 11225631 11247495

9 4.75 5.16667 6.5 5.5 10 5 3.5 15.5 4 6.5 7.5 5 6.4 3.5 3.75 11.75 4.5 3.8 4.6 5.5 3.75 4 5.5 4.2 5.75 3.5 3.75 3.75 4.2 4.2 5.5 5.5 3.2 4.25 16.5 5.5 5.33333 3.75 8 14.5 4.5 6.5 5 7.5 5 9.5 3.75 5 3.25 13.5 4.5 4.33333 6 5 5.5 5 5.5 5 4.75 8 4.25 5.5 6.25 5.5 7.5 5.5 4.2 10.5 6.33333 5.5 8.5 14 5.5 6.66667 3.4 6.5 4.75 5.66667 6.5 4.75 7.25 4.5 4

ENSSSCT00000012241 . ENSSSCT00000012246 ENSSSCT00000012246 . . . . ENSSSCT00000012249 ENSSSCT00000012249 ENSSSCT00000012249 . . ENSSSCT00000032548 . ENSSSCT00000012259 ENSSSCT00000012259 ENSSSCT00000012259 ENSSSCT00000012259 . . . . . . . . ENSSSCT00000012264 ENSSSCT00000012265 ENSSSCT00000012264 ENSSSCT00000012265 ENSSSCT00000012264 ENSSSCT00000012265 . . . . . ENSSSCT00000012267 . . . . . . . . . . ENSSSCT00000012270 ENSSSCT00000012270 ENSSSCT00000012271 ENSSSCT00000012271 ENSSSCT00000012271 ENSSSCT00000024917 ENSSSCT00000024917 . . . . . . . . . . ENSSSCT00000012274 . . . . . . . . . . . . . . . . .

CPNE4 . ATP2C1 ATP2C1 . . . . COL6A5 COL6A5 COL6A5 . . SH3BP5 . ANKRD28 ANKRD28 ANKRD28 ANKRD28 . . . . . . . . TBC1D5 TBC1D5 TBC1D5 TBC1D5 TBC1D5 TBC1D5 . . . . . SATB1 . . . . . . . . . . KCNH8 KCNH8 EFHB EFHB EFHB KAT2B KAT2B . . . . . . . . . . ZNF385D . . . . . . . . . . . . . . . . .

intron intergenic intron intron intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intron intergenic intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

0.295 . 0.032 . 0.618 -0.155 0.289 -0.047 0.103 0.852 0.087 . . -0.108 . 0.194 0.048 0.181 . . . . 0.154 0.41 0.057 0.136 -0.059 0.408 0.408 0.145 0.145 0.102 0.102 0.3 0.425 0.113 0.471 . -0.241 0.207 -0.09 0.416 -0.229 0.51 -0.033 -0.108 . -0.087 0.074 0.059 0.148 . 0.181 0.594 . -0.255 . 0.044 . . -0.13 -0.202 . 0.134 . 0.367 0.205 -0.111 . -0.04 -0.186 . 0.038 . . 0.042 -0.087 0.07 0.345 0.081 -0.025 . 0.135 -0.063

. rs793535439 844126 rs7864 193548 rs7921 . rs789654903 rs791633651 rs791994657 694311 rs7913 rs789354620 . rs790708406 rs788789861 rs787533892 rs792967134 rs790320256 840974 rs7902 rs793117341 359180 rs7902 rs788376436 . rs789013397 394961 rs7935 rs791505356 rs790731392 218848 rs7909 rs793254451 rs790715038 rs790715038 rs793804749 rs793804749 rs787642185 rs787642185 675718 rs7863 976534 rs7874 901165 rs7922 rs792279375 . rs792776629 . 272536 rs7894 rs793343215 rs793242763 rs786348939 031236 rs7936 rs792159334 011652 rs7909 425800 rs7894 . rs786779855 . rs787868331 rs709925234 rs787086315 rs793575345 rs789588750 rs787232243 . rs791392229 812116 rs7887 447951 rs7871 rs788098360 . rs793625084 544007 rs7878 rs788928957 . . rs790582602 041657 rs7937 rs788795698 rs787336068 . rs790301135 370213 rs7932 rs789246528 rs792119252 481239 rs7881 rs792440453 rs789177049 . . rs792929112 .

4 2 2 2 2 3 3 2 2 2 3 3 2 2 3 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 4 4 2 2 3 4 2 2 2 2 2 2 2 7 2 2 2 3 2 2 2 2 2 2 3 2 4 3 2 2 3 7 2 2 2 4 2 2 3 2 2 2 2 2 2 4 2 2 2 2 2 2 2

AG.CT AAAT.ATTT AG.CT AAAAG.CTTTT AAAC.GTTT AAAC.GTTT AG.CT ATC.GAT AC.GT AC.GT AG.CT AC.GT AC.GT AAAAGG.CCTTTT AC.GT AC.GT AT.AT AC.GT AT.AT AAAC.GTTT AG.CT AAT.ATT AGATAT.ATATCT AAAAT.ATTTT AAAAT.ATTTT AC.GT AAT.ATT AG.CT AG.CT AAAG.CTTT AT.AT AAAAAC.GTTTTT AAT.ATT AG.CT AAAC.GTTT AAAT.ATTT AAC.GTT AAAAAT.ATTTTT AAC.GTT AAAC.GTTT AT.AT AAAT.ATTT AATT.AATT AATT.AATT AAAC.GTTT AAAC.GTTT AAAG.CTTT AAAG.CTTT AT.AT AAAAC.GTTTT ACAG.CTGT AAC.GTT AC.GT AT.AT AC.GT AC.GT AC.GT AC.GT AAAC.GTTT AC.GT AAT.ATT AC.GT AG.CT AC.GT AAC.GTT AT.AT AT.AT AAAAT.ATTTT AG.CT AGG.CCT AC.GT AAAAC.GTTTT AC.GT AAAAAC.GTTTTT AC.GT AAT.ATT AAC.GTT AT.AT AAC.GTT AT.AT AAAC.GTTT AC.GT AC.GT AAAC.GTTT

13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13

11267607 11293284 11338888 11432752 11475723 11566215 11649728 11653998 11707485 11707485 11863531 12188318 12338607 12436621 12493057 12540012 12659955 12800126 12954072 13000721 13042411 13185781 13243319 13327848 13346123 13360656 13378917 13474705 13827964 13922930 14172457 14279431 14639389 14762658 14819146 14861327 14923909 15050479 15120208 15166107 15166250 15264875 15439573 15439573 15470473 15470473 15499308 16007952 16226120 16326862 16550752 16613380 17000409 17249037 17405196 17428581 17444931 17563590 17701480 17770440 18466822 18594917 18694510 18730094 18870291 19169060 19415332 19453310 19503297 19637750 19682684 19830763 19906288 19913016 20001883 20086769 20091838 20103954 20124742 20257325 20419022 20490591 20490591 20586775

11267618 11293302 11338900 11432768 11475737 11566239 11649738 11654017 11707494 11707494 11863541 12188334 12338619 12436641 12493077 12540030 12659967 12800143 12954099 13000739 13042426 13185792 13243350 13327872 13346138 13360672 13378934 13474730 13827979 13922949 14172470 14279453 14639401 14762667 14819160 14861347 14923936 15050502 15120223 15166125 15166260 15264899 15439594 15439594 15470487 15470487 15499325 16007968 16226135 16326878 16550764 16613394 17000421 17249046 17405207 17428595 17444942 17563600 17701494 17770451 18466846 18594936 18694541 18730112 18870308 19169070 19415341 19453328 19503309 19637766 19682696 19830792 19906299 19913036 20001893 20086787 20091855 20103964 20124754 20257337 20419038 20490601 20490601 20586789

6 4.75 6.5 3.4 3.75 6.25 5.5 6.66667 5 5 5.5 8.5 6.5 3.5 10.5 9.5 6.5 9 14 4.75 8 4 5.33333 5 3.2 8.5 6 13 8 5 7 3.83333 4.33333 5 3.75 5.25 9.33333 4 5.33333 4.75 5.5 6.25 5.5 5.5 3.75 3.75 4.5 4.25 8 3.4 3.25 5 6.5 5 6 7.5 6 5.5 3.75 6 8.33333 10 16 9.5 6 5.5 5 3.8 6.5 5.66667 6.5 6 6 3.5 5.5 6.33333 6 5.5 4.33333 6.5 4.25 5.5 5.5 3.75

. . . . . . . . ENSSSCT00000012275 ENSSSCT00000035075 . . . ENSSSCT00000012277 ENSSSCT00000012277 . . . . . . . . . . . . . . . ENSSSCT00000012279 ENSSSCT00000012280 . . . . . . . . . . ENSSSCT00000012284 ENSSSCT00000012283 ENSSSCT00000012284 ENSSSCT00000012283 ENSSSCT00000012285 . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000012296 ENSSSCT00000012297 ENSSSCT00000012297 ENSSSCT00000012297 ENSSSCT00000012297 ENSSSCT00000012297 ENSSSCT00000012297 ENSSSCT00000012297 ENSSSCT00000012297 . . ENSSSCT00000026794 ENSSSCT00000030407 .

. . . . . . . . UBE2E2 UBE2E2 . . . THRB THRB . . . . . . . . . . . . . . . TOP2B NGLY1 . . . . . . . . . . NEK10 NEK10 NEK10 NEK10 SLC4A7 . . . . . . . . . . . . . . . . . . . . . . . STT3B OSBPL10 OSBPL10 OSBPL10 OSBPL10 OSBPL10 OSBPL10 OSBPL10 OSBPL10 . . CMTM8 CMTM8 .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intron intron intron intergenic intergenic intron intron intergenic

0.336 0.414 -0.003 0.259 0.099 0.356 0.161 -0.003 . . . -0.079 . 0.591 0.769 0.137 0.127 -0.123 0.165 . 0.075 0.068 . -0.089 -0.267 -0.037 -0.067 0.009 -0.047 . 0.183 0.266 -0.075 -0.095 . 0.186 . 0.188 -0.075 0.182 0.107 0.214 0.528 0.528 0.117 0.117 2.153 -0.151 0.008 . -0.422 . -0.021 . -0.278 -0.264 0.092 -0.031 0.024 0.934 0.047 -0.202 -0.173 0.134 0.115 0.194 0.107 -0.024 . 0.206 0.116 -0.063 . . -0.091 0.343 -0.004 -0.315 -0.053 . 0.095 0.02 0.02 .

. rs786645934 rs787007697 rs786903113 765599 rs7923 . . rs791592517 . . rs791006428 . rs792620503 820136 rs7873 148160 rs7921 rs793545909 168273 rs7888 413926 rs7863 . . rs791126904 rs788261872 rs789131309 rs789529248 rs789228912 rs786937662 rs791836680 533439 rs7903 rs787657263 rs792412171 915503 rs7893 rs787035754 rs791581923 . rs789595618 303616 rs7895 rs792869017 rs793199945 . rs789200198 rs787484679 rs788616890 rs792253824 rs792253824 rs787813529 rs787813529 rs788542756 rs787614402 rs787375335 609853 rs6900 rs793381989 . 824500 rs7877 rs788275271 . . . rs790212611 rs790221028 . . rs789050651 rs789137709 rs790393039 088608 rs7915 rs789410952 rs786790125 rs792708129 rs789822881 rs788980750 735707 rs7938 rs789579719 . rs700450684 rs792618394 rs792979632 rs707838022 rs792862113 . 223348 rs7878 962779 rs7886 rs690275310 rs690275310 rs790077680

4 2 2 2 2 2 2 2 2 2 2 4 3 2 2 2 2 4 4 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 5 2 2 2 2 2 2 2 2 2 2 3 2 2 3 2 2 2 2 3 2 2 2 2 2 2 4 2 4 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2

AT.AT AT.AT AAAAAC.GTTTTT AAAAAC.GTTTTT AC.GT AT.AT AC.GT AT.AT AC.GT AAAC.GTTT AAAC.GTTT AGAT.ATCT AC.GT AG.CT AC.GT AAAC.GTTT AAAAC.GTTTT AT.AT AG.CT AAAC.GTTT AAAT.ATTT AC.GT AAAT.ATTT AAAAT.ATTTT AC.GT AATG.CATT AC.GT AG.CT AC.GT AAC.GTT AC.GT AC.GT AAAC.GTTT AC.GT AAAT.ATTT AC.GT AT.AT AAT.ATT AAAG.CTTT AT.AT AT.AT AAAAAC.GTTTTT ATCC.GGAT AT.AT AAGG.CCTT AT.AT AAAAC.GTTTT AAAAT.ATTTT AC.GT AAAG.CTTT AT.AT AAAC.GTTT AAAC.GTTT ATCC.GGAT AC.GT AAC.GTT AC.GT AAAAG.CTTTT AAC.GTT AC.GT AG.CT AAAT.ATTT AAAC.GTTT AT.AT AG.CT AT.AT AAAC.GTTT AAC.GTT AC.GT AAC.GTT AT.AT AAAAC.GTTTT ACC.GGT AAAG.CTTT AAAG.CTTT AT.AT AATCAT.ATGATT AG.CT AG.CT AC.GT AG.CT AAAAC.GTTTT AAAAC.GTTTT AAAC.GTTT

13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13

21034786 21034786 21096735 21096735 21403631 22057288 22129813 22158238 22642202 22791856 22811373 23166871 23288776 23499149 23528267 23533664 23556659 23636741 23798289 23825414 24000568 24666870 24719539 25473356 25597883 25614771 25741247 25797457 25983994 26044919 26073005 26073005 26302383 26449628 26583128 26657314 26689813 27030611 27391519 27547545 27553434 27589977 27599815 27634646 27687245 27783683 27845862 27907846 27916849 28166147 28175575 28203800 28487920 28493356 28500128 28564660 28603760 28865856 28949406 29109597 29708209 29753039 29930167 29955403 30055044 30085698 30224034 30629480 30723803 30811178 30866688 30955083 31302836 31329055 31435242 31562695 31581192 32197752 32298166 32542826 32717675 33094126 33094126 33310562

21034800 21034800 21096763 21096763 21403651 22057302 22129825 22158255 22642221 22791873 22811386 23166907 23288788 23499173 23528277 23533684 23556695 23636750 23798301 23825428 24000586 24666892 24719557 25473379 25597900 25614800 25741256 25797479 25984004 26044930 26073017 26073017 26302398 26449638 26583145 26657332 26689823 27030631 27391536 27547558 27553444 27590000 27599841 27634657 27687280 27783693 27845879 27907863 27916858 28166165 28175590 28203819 28487940 28493392 28500140 28564680 28603770 28865881 28949434 29109607 29708224 29753053 29930184 29955419 30055053 30085707 30224059 30629493 30723814 30811191 30866714 30955121 31302849 31329073 31435260 31562706 31581214 32197765 32298193 32542837 32717701 33094149 33094149 33310580

7.5 7.5 4.83333 4.83333 10.5 7.5 6.5 9 10 4.5 3.5 9.25 6.5 12.5 5.5 5.25 7.4 5 6.5 3.75 4.75 11.5 4.75 4.8 9 7.5 5 11.5 5.5 4 6.5 6.5 4 5.5 4.5 9.5 5.5 7 4.5 7 5.5 4 6.75 6 9 5.5 3.6 3.6 5 4.75 8 5 5.25 9.25 6.5 7 5.5 5.2 9.66667 5.5 8 3.75 4.5 8.5 5 5 6.5 4.66667 6 4.66667 13.5 7.8 4.66667 4.75 4.75 6 3.83333 7 14 6 13.5 4.8 4.8 4.75

ENSSSCT00000012303 ENSSSCT00000025077 ENSSSCT00000012303 ENSSSCT00000025077 . . . . . ENSSSCT00000012305 ENSSSCT00000012305 . . . . . . ENSSSCT00000027443 . . . ENSSSCT00000030803 ENSSSCT00000030803 ENSSSCT00000012326 ENSSSCT00000012327 . ENSSSCT00000012328 . . ENSSSCT00000028766 ENSSSCT00000022750 ENSSSCT00000012331 ENSSSCT00000029630 ENSSSCT00000012335 . ENSSSCT00000012336 ENSSSCT00000012336 . . . . . . ENSSSCT00000012342 . . . . . . . ENSSSCT00000029576 . . . ENSSSCT00000012347 ENSSSCT00000012347 . ENSSSCT00000012360 . ENSSSCT00000012366 ENSSSCT00000012366 . . . . . . ENSSSCT00000012375 ENSSSCT00000012379 ENSSSCT00000012380 . ENSSSCT00000024122 . . ENSSSCT00000012384 ENSSSCT00000012384 ENSSSCT00000035018 . . . ENSSSCT00000025127 ENSSSCT00000012405 .

CLASP2 CLASP2 CLASP2 CLASP2 . . . . . ARPP21 ARPP21 . . . . . . MLH1 . . . . . EXOG SCN5A . SCN10A . . GORASP1 TTC21A TTC21A SLC25A38 MOBP . . . . . . . . . CTNNB1 . . . . . . . . . . . TRAK1 TRAK1 . HIGD1A . ANO10 ANO10 . . . . . . ZNF197 KIAA1143 KIF15 . . . . . . FYCO1 . . . . . .

intron intron promoter promoter intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intron intron intron intron intergenic intron intergenic intergenic 3'utr intron intron intron promoter intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intron 3'utr intergenic intron intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic promoter promoter intron intergenic intron intergenic intergenic intron intron intron intergenic intergenic intergenic intron intron intergenic

. . -0.318 -0.318 0.073 0.191 0.71 -0.146 . 0.004 -0.267 . . 0.004 . 0.257 . . 0.397 . 0.226 0.207 2.45 0.188 -0.039 0.095 -0.042 0.078 . 1.079 -0.127 -0.127 -0.045 0.013 0.086 -0.077 0.193 . 0.512 -0.12 -0.094 0.045 . -0.017 . . . . 0.065 0.03 -0.019 . . 0.477 -0.203 -0.093 0.473 . 0.171 0.193 0.182 0.228 -0.062 -0.004 -0.068 0.183 -0.044 . 0.189 0.162 0.022 . -0.124 0.132 -0.236 0.021 0.057 -0.486 -0.068 -0.23 -0.153 -0.052 -0.052 0.127

rs791571602 rs791571602 rs701351268 rs701351268 rs789289119 . . . 672120 rs7893 rs788596871 892823 rs7932 263530 rs7866 405065 rs7881 . . rs789821148 rs790044559 . . rs792261865 rs789058024 . rs787443306 766845 rs7906 . rs792519025 860217 rs7111 615796 rs7892 rs788203292 rs791676965 rs788352832 rs788352832 rs791835222 rs793000087 rs787080389 rs789092451 rs789364549 rs791501570 rs790338659 227807 rs7869 . 871176 rs7866 259229 rs7915 rs787241206 795207 rs7864 . rs710615137 . . rs790362967 rs789808395 481202 rs7906 522589 rs7903 rs792471742 533455 rs7908 rs793476475 rs786550572 rs791011066 rs787505788 rs790846018 314575 rs7894 492068 rs7862 rs792970677 rs786291030 rs791213493 . 232060 rs7870 254839 rs7911 rs790066577 rs790562658 rs787287836 rs790020294 338420 rs7904 rs790795922 rs791510199 rs788364185 rs789956898 244643 rs7886 rs792986480 rs792264969 rs793629680 rs788524594 rs788524594 rs790291429

2 2 2 2 2 2 4 3 2 2 2 2 2 4 2 2 2 4 3 2 2 4 2 2 2 2 4 2 2 2 2 2 2 2 2 2 3 2 2 2 3 2 2 2 2 3 2 2 3 2 3 3 2 2 2 4 2 2 2 2 2 2 2 2 2 4 2 2 3 3 2 3 3 2 2 2 3 2 2 2 4 2 2 2

AC.GT AAAC.GTTT AAC.GTT AATG.CATT AAAT.ATTT AAAT.ATTT AC.GT AATC.GATT AC.GT AC.GT AAAC.GTTT AG.CT AG.CT AC.GT AAAAC.GTTTT AAAC.GTTT AAAG.CTTT AAAAC.GTTTT AC.GT AAAAT.ATTTT AG.CT AC.GT AC.GT AG.CT AGCCC.GGGCT GGCCC.GGGCC AAAT.ATTT AC.GT AAAAC.GTTTT AAAT.ATTT AC.GT AAGG.CCTT AT.AT AG.CT AAC.GTT ACC.GGT AAAC.GTTT AAAC.GTTT AT.AT AAAC.GTTT AG.CT AAAG.CTTT AAAG.CTTT AAC.GTT AAAT.ATTT AT.AT AG.CT AAAAAC.GTTTTT AAACC.GGTTT AAACC.GGTTT AT.AT ACAT.ATGT AC.GT AAC.GTT AT.AT AC.GT AAAC.GTTT AAAC.GTTT AC.GT AT.AT AC.GT AG.CT AAAC.GTTT AAAT.ATTT AT.AT AG.CT AC.GT AAT.ATT AAGG.CCTT AG.CT AG.CT AC.GT AAT.ATT AC.GT AC.GT AG.CT AG.CT ATC.GAT AAAAC.GTTTT AGG.CCT AC.GT AC.GT AC.GT AAAC.GTTT

13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13

33312926 33437611 33533443 33555282 33729264 33729264 33798903 34006501 34028286 34495018 35531933 35814319 35968380 36217366 36477339 36486841 36872806 36890017 37686813 38046664 38167587 38648424 38685415 38744672 38942621 38943801 39233286 39382690 39914601 40205123 40625837 40929189 41522244 41533755 41769319 41972450 42178222 42242870 42243463 42348829 42412112 42772852 42856153 43007976 43331626 43447055 44059671 44141302 44755043 44755043 44943325 45150495 45325393 45406956 45567727 45882309 45988116 46017568 46130984 46328112 46402002 46457090 47291955 47312699 47318549 47656411 47714460 47732354 48212530 48755712 48853984 48878673 49325975 49532102 49549173 49571998 49679548 49738268 49764492 50084104 50101760 50162419 50162419 50274277

33312937 33437631 33533456 33555316 33729287 33729287 33798913 34006523 34028296 34495030 35531964 35814341 35968396 36217381 36477362 36486856 36872820 36890041 37686828 38046687 38167606 38648433 38685429 38744689 38942643 38943823 39233301 39382716 39914621 40205141 40625858 40929208 41522263 41533767 41769338 41972462 42178241 42242890 42243474 42348852 42412121 42772870 42856164 43007992 43331653 43447067 44059681 44141329 44755063 44755063 44943335 45150510 45325404 45406972 45567739 45882326 45988145 46017582 46131014 46328137 46402018 46457100 47291973 47312718 47318559 47656420 47714470 47732365 48212542 48755723 48853998 48878682 49326004 49532114 49549183 49572007 49679572 49738282 49764513 50084127 50101772 50162442 50162442 50274291

6 5.25 4.66667 8.75 6 6 5.5 5.75 5.5 6.5 8 11.5 8.5 8 4.8 4 3.75 5 8 4.8 10 5 7.5 9 4.6 3.83333 4 13.5 4.2 4.75 11 5 10 6.5 6.66667 4.33333 5 5.25 6 6 5 4.75 3 5.66667 7 6.5 5.5 4.66667 4.2 4.2 5.5 4 6 5.66667 6.5 9 7.5 3.75 15.5 13 8.5 5.5 4.75 5 5.5 5 5.5 4 3.25 6 7.5 5 10 6.5 5.5 5 12.5 5 4.4 8 6.5 12 12 3.75

. . . . ENSSSCT00000023426 ENSSSCT00000012417 ENSSSCT00000012417 . . ENSSSCT00000012430 . . ENSSSCT00000029394 . . . . . ENSSSCT00000025398 ENSSSCT00000012526 . . . . ENSSSCT00000012536 ENSSSCT00000012536 . . ENSSSCT00000023696 ENSSSCT00000024071 . . ENSSSCT00000030632 ENSSSCT00000030632 ENSSSCT00000028128 . . . . ENSSSCT00000028725 . . . . ENSSSCT00000012546 . ENSSSCT00000012556 . ENSSSCT00000012564 ENSSSCT00000012565 . . . . . . . . . . . . . . . . . ENSSSCT00000012568 ENSSSCT00000012572 . . . . ENSSSCT00000023657 ENSSSCT00000023657 ENSSSCT00000023657 ENSSSCT00000012575 . . . ENSSSCT00000012578 ENSSSCT00000012578 ENSSSCT00000020410 .

. . . . . . . . . PFKFB4 . . IFRD2 . . . . . DNAH1 NEK4 . . . . . . . . . . . . . . . . . . . FAM208A . . . . PDE12 . PXK . C3orf67 C3orf67 . . . . . . . . . . . . . . . . . PTPRG CADPS . . . . SYNPR SYNPR SYNPR SNTN . . . PRICKLE2 PRICKLE2 7SK .

intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intron intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intron intron intergenic intergenic intron intron intergenic intergenic intron intron intron intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic 3'utr intergenic intron intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intron intron promoter intergenic

0.142 . . . . . 2.621 -0.046 0.248 0.877 . -0.247 -0.026 0.436 0.173 . 0.214 1.252 -0.243 0.288 . -0.691 -0.031 -0.086 -0.076 -0.244 . 0.087 -0.057 -0.065 0.564 0.086 0.189 0.25 0.059 0.101 . 0.469 -0.351 0.002 . -0.163 0.074 . 0.461 0.123 . -0.101 . . . 0.381 . 1.155 . 0.024 0.392 -0.393 0.464 0.052 . 1.064 . 0.977 -0.064 -0.126 -0.026 -0.233 0.073 -0.094 0.049 0.121 0.008 0.061 0.301 0.074 -0.199 -0.023 -0.017 0.029 -0.001 -0.159 -0.159 .

rs793592069 rs791748963 145069 rs7932 303525 rs7913 405113 rs7888 405113 rs7888 rs696260336 010919 rs7876 rs793491676 rs792183956 rs790231630 . . rs790515932 rs789667610 rs786308065 rs792150056 555610 rs7886 rs787490335 610602 rs7909 rs712945353 . rs789075309 rs793601963 427140 rs7884 rs787102476 rs787355941 . rs791793745 rs786360471 . rs786739210 . . rs791743426 rs786313758 rs790442654 rs788475631 rs786719828 rs790243017 rs787030650 rs790003471 rs788981400 901050 rs7889 rs788681578 353666 rs7863 . rs791912056 rs790525899 rs790525899 rs786255695 rs787310034 883237 rs7867 rs790696620 rs788609955 rs791011441 368409 rs7875 rs789395611 rs788772261 rs786746624 . . rs789083373 073343 rs7892 rs787985369 . 066835 rs7910 rs787181173 . . rs789117854 . 229219 rs7916 rs786878749 rs786613344 rs692533966 rs791347164 rs792101039 138311 rs7921 rs787886527 rs787582462 . . 514076 rs7923

2 2 2 2 2 2 4 2 2 3 2 4 3 4 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 4 2 2 3 2 2 2 2 3 3 2 3 2 2 2 2 2 3 2 2 2 2 4 3 3 2 3 2 4 2 2 2 3 2 2 2 2 2 3 3 3

AAAC.GTTT AAAC.GTTT AC.GT AAT.ATT AAAC.GTTT AT.AT AAAC.GTTT AAAAAC.GTTTTT AAAT.ATTT AAG.CTT AATG.CATT AAAAG.CTTTT ACAT.ATGT AAAG.CTTT AAAT.ATTT AG.CT AAAG.CTTT AAAG.CTTT AT.AT AAC.GTT AG.CT AAAAT.ATTTT ACAT.ATGT AACAC.GTGTT AAAT.ATTT AC.GT AAAAC.GTTTT AAAAC.GTTTT AC.GT AAAC.GTTT ATC.GAT AC.GT AC.GT AC.GT AAACC.GGTTT AAC.GTT AAG.CTT AAT.ATT AAC.GTT AAAC.GTTT AAG.CTT AATG.CATT AC.GT AG.CT AG.CT AAAC.GTTT AT.AT AT.AT AT.AT AT.AT AT.AT AC.GT AC.GT AC.GT ACC.GGT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AG.CT AAAC.GTTT AAAC.GTTT ACAT.ATGT AT.AT AAAAT.ATTTT AC.GT AAAT.ATTT ACAT.ATGT AAAAAG.CTTTTT AAATT.AATTT AAAC.GTTT AT.AT AC.GT AC.GT AG.CT AAC.GTT AAAT.ATTT AAAAC.GTTTT AAAG.CTTT AT.AT AAAAG.CTTTT AT.AT AAAG.CTTT AAAC.GTTT AG.CT

13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13

50317993 50375451 50375879 50940234 51006787 51132467 51390483 51755788 51855328 51924829 52020468 52048922 52112916 52285023 52444143 52882811 53138151 53268364 53915841 54122260 54146399 54672903 55172700 55873707 55993370 56055724 56068553 56397756 56439631 56728682 56813348 57191947 57380990 57773298 57893084 58553913 58672860 58829741 58934280 58981208 59209195 59431092 59578169 59681886 59772469 59847718 59945999 59945999 60006780 60006780 60109083 60298782 60410003 60528516 60534823 60538022 60612891 60645765 61106715 61219753 61471390 61605868 61885989 61911220 61965120 62525769 63001840 63062302 63243666 63252226 63267140 63483337 63509129 63526322 64274214 64834916 64845159 65050157 65141367 65644426 65740502 65767130 65787763 65819747

50318020 50375477 50375899 50940253 51006805 51132476 51390499 51755816 51855353 51924841 52020490 52048939 52112934 52285048 52444166 52882825 53138168 53268382 53915850 54122273 54146408 54672918 55172722 55873730 55993392 56055736 56068581 56397776 56439648 56728711 56813365 57191966 57381011 57773307 57893116 58553926 58672876 58829765 58934312 58981232 59209209 59431124 59578189 59681897 59772481 59847748 59946024 59946024 60006790 60006790 60109101 60298792 60410026 60528528 60534840 60538042 60612910 60645783 61106732 61219767 61471406 61605882 61886004 61911243 61965130 62525783 63001862 63062319 63243688 63252240 63267151 63483349 63509140 63526336 64274225 64834939 64845181 65050171 65141379 65644448 65740513 65767148 65787781 65819757

7 6.75 10.5 6.66667 4.75 5 4.25 4.83333 6.5 4.33333 5.75 3.6 4.75 6.5 6 7.5 4.5 4.75 5 4.66667 5 3.2 5.75 4.8 5.75 6.5 5.8 4.2 9 7.5 6 10 11 5 6.6 4.66667 5.66667 8.33333 11 6.25 5 8.25 10.5 6 6.5 7.75 13 13 5.5 5.5 9.5 5.5 12 6.5 6 5.25 5 3.8 9 3.75 4.25 3.75 8 4.8 5.5 3.75 5.75 3 4.6 3.75 6 6.5 6 7.5 4 6 4.6 3.75 6.5 4.6 6 4.75 4.75 5.5

. . . . . . . ENSSSCT00000012581 . . . . . . . . . . ENSSSCT00000012586 . . . . ENSSSCT00000012598 . . . . . . . . . . ENSSSCT00000022793 . . . . . . . . . ENSSSCT00000012605 ENSSSCT00000012605 ENSSSCT00000024001 ENSSSCT00000012607 ENSSSCT00000024001 ENSSSCT00000012607 . . . . . . . . . . . ENSSSCT00000012610 . . . . . . . . . . . . . . . . . . . . . .

. . . . . . . MAGI1 . . . . . . . . . . SUCLG2 . . . . FRMD4B . . . . . . . . . . . . . . . . . . . . SHQ1 SHQ1 GXYLT2 GXYLT2 GXYLT2 GXYLT2 . . . . . . . . . . . CNTN3 . . . . . . . . . . . . . . . . . . . . . .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

0.355 -0.13 . -0.494 0.524 0.085 0.163 0.707 -0.145 . -0.052 0.092 -0.101 -0.141 . -0.399 -0.349 . 0.001 . -0.228 . . -0.045 0.098 -0.021 0.189 0.085 0.044 0.154 0.08 0.157 -0.195 -0.091 -0.192 -0.131 -0.058 . 0.149 0.007 -0.056 -0.21 . -0.098 0.234 0.126 . . -0.119 -0.119 0.145 -0.037 -0.061 -0.062 -0.284 -0.382 -0.09 -0.165 . 0.007 . -0.125 0.028 0.027 -0.126 . 0.11 -0.06 -0.23 -0.105 -0.171 -0.014 -0.119 . -0.071 0.098 -0.164 0.577 -0.192 0.416 0.272 0.587 -0.078 0.161

. rs787025699 . rs787336480 470768 rs7897 rs791389124 rs791270571 rs704150598 959390 rs7883 830978 rs7938 rs792183963 . . rs787159703 rs789811949 rs793455553 678822 rs7892 . rs790885087 rs792541616 . rs792250497 884859 rs7932 852894 rs7898 747772 rs7936 rs792922318 rs788508069 556492 rs7897 429265 rs7868 754937 rs7890 rs786327247 rs701370608 364485 rs7884 . 674033 rs7870 rs791148983 . rs793496951 193924 rs7026 rs789561223 170744 rs7865 rs792205396 062378 rs7869 rs790919278 rs793190558 rs790783651 196400 rs7916 196400 rs7916 411582 rs7863 411582 rs7863 rs786925911 rs704071348 rs790172442 rs786278605 rs788710245 567711 rs7903 rs788630418 rs788634207 627868 rs7871 476763 rs7905 rs793855624 . rs789468932 rs792404628 rs786889732 rs788026106 rs790475416 rs786961117 rs790880635 rs789625145 rs792413675 . 220841 rs7932 179272 rs7883 rs789668333 rs790192565 158096 rs7883 rs792726466 066379 rs7932 585191 rs7897 rs787566944 rs788857402 983522 rs7885 rs791993592

2 2 4 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 3 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 6 2 3 2 2 2 2 2 2 2 2 2 3 4 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 4 3 2 2 4 2 2 2 2 2 2

AAAC.GTTT AC.GT AAAT.ATTT AAAAC.GTTTT AAAAT.ATTTT AAAC.GTTT AAC.GTT AAT.ATT AAGAGG.CCTCT AAAC.GTTT AAAAT.ATTTT AAAT.ATTT AC.GT AC.GT AAAC.GTTT AAAT.ATTT AAC.GTT AAAT.ATTT AT.AT AG.CT AT.AT AC.GT AAAC.GTTT AGAT.ATCT AG.CT AAG.CTT AAAAC.GTTTT AG.CT AAAC.GTTT AAT.ATT AAAT.ATTT AAAG.CTTT ACAT.ATGT AAAAC.GTTTT AAT.ATT AAAC.GTTT AGAT.ATCT AAAGAG.CTCTTT AAAAT.ATTTT AG.CT AC.GT AGG.CCT AT.AT AT.AT AGAGGG.CCCTC AAAC.GTTT AAAAC.GTTTT AAAT.ATTT CCCCC.GGGGG AT.AT AT.AT AAAC.GTTT AAAC.GTTT AAAT.ATTT AC.GT AAAC.GTTT AAC.GTT AC.GT AATG.CATT AAC.GTT AAAC.GTTT AAAC.GTTT AC.GT AAC.GTT AAAT.ATTT AAAT.ATTT AAC.GTT AAAC.GTTT AG.CT AAAAC.GTTTT AC.GT AAAC.GTTT AT.AT AAC.GTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AC.GT AAAC.GTTT AAAG.CTTT AAT.ATT AAAC.GTTT AAAAC.GTTTT AAAT.ATTT

13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13

65896023 65944338 65995850 66169775 66503751 66717698 66868541 66896419 67337864 67352732 67845643 67982374 68170289 68183825 68211672 68246111 68251274 68526303 68824348 69031669 69236359 69291988 69462333 69626060 69629850 69665943 70356290 70533132 70595017 70697249 70754559 70930557 71255699 71356395 71402307 71815706 72192588 72789793 72905961 73210770 73588113 73863692 74409593 74415513 74707410 74762683 74876573 74968446 74989473 75440072 75568087 76042237 76042237 76835228 77154110 77497413 78671702 78686757 78999136 79399924 79756435 79811698 79873323 79892784 79907799 80948079 81054073 81125911 81184245 81435127 81644410 81705442 81751732 81952558 82041611 82335551 82420795 82517483 82881653 82961383 82970523 83063280 83085858 83250505

65896037 65944362 65995874 66169792 66503771 66717724 66868552 66896436 67337886 67352754 67845668 67982396 68170308 68183842 68211690 68246126 68251293 68526321 68824358 69031681 69236372 69292012 69462351 69626089 69629861 69665956 70356308 70533142 70595032 70697273 70754577 70930591 71255713 71356418 71402326 71815724 72192602 72789811 72905975 73210789 73588128 73863704 74409607 74415524 74707435 74762699 74876588 74968459 74989489 75440081 75568096 76042259 76042259 76835250 77154121 77497449 78671715 78686768 78999162 79399940 79756459 79811715 79873340 79892796 79907818 80948098 81054098 81125922 81184255 81435148 81644422 81705461 81751743 81952573 82041625 82335569 82420811 82517494 82881668 82961405 82970536 83063298 83085881 83250531

3.75 12.5 6.25 3.6 4.2 6.75 4 6 3.83333 5.75 5.2 5.75 10 9 4.75 4 6.66667 4.75 5.5 6.5 7 12.5 4.75 7.5 6 4.66667 3.8 5.5 4 8.33333 4.75 8.75 3.75 4.8 6.66667 4.75 3.75 3.16667 3 10 8 4.33333 7.5 6 4.33333 4.25 3.2 3.5 2.83333 5 5 5.75 5.75 5.75 6 9.25 4.66667 6 6.75 5.66667 6.25 4.5 9 4.33333 5 5 8.66667 3 5.5 4.4 6.5 5 6 5.33333 3.75 4.75 4.25 6 4 5.75 4.66667 4.75 4.8 6.75

. . . ENSSSCT00000012620 . . . . ENSSSCT00000012622 . . . . . . . . . . . . . . . . . . . ENSSSCT00000031304 ENSSSCT00000031304 ENSSSCT00000031304 ENSSSCT00000031304 . . . . . . ENSSSCT00000012630 ENSSSCT00000012645 ENSSSCT00000013960 . . ENSSSCT00000027036 ENSSSCT00000012667 ENSSSCT00000012667 ENSSSCT00000012667 . . . . ENSSSCT00000012675 ENSSSCT00000031032 ENSSSCT00000012690 . ENSSSCT00000012696 ENSSSCT00000012707 ENSSSCT00000012707 . ENSSSCT00000012708 . ENSSSCT00000012719 . ENSSSCT00000012717 ENSSSCT00000012717 . . . ENSSSCT00000012725 ENSSSCT00000012730 . . . . ENSSSCT00000012735 ENSSSCT00000023415 . ENSSSCT00000012738 ENSSSCT00000012743 . . . . .

. . . CRBN . . . . SUMF1 . . . . . . . . . . . . . . . . . . . GRM7 GRM7 GRM7 GRM7 . . . . . . SETD5 RPUSD3 ATP2B2 . . . ATG7 ATG7 ATG7 . . . . . . NR2C2 . . NUP210 NUP210 . HMCES . KBTBD12 . . . . . . DNAJC13 . . . . . BFSP2 . . RAB6B RYK . . . . .

intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intron promoter intron intergenic intergenic promoter intron intron intron intergenic intergenic intergenic intergenic intron intron intron intergenic intron intron intron intergenic intron intergenic intron intergenic intron intron intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intron intron intergenic intron intron intergenic intergenic intergenic intergenic intergenic

0.358 -0.039 . 1.182 -0.041 0.075 . 0.244 0.352 . 0.106 . 0.061 -0.086 -0.151 -0.097 0.002 -0.055 -0.147 . -0.226 -0.16 0.046 . -0.049 0.154 -0.197 0.468 0.035 0.04 0.561 -0.117 -0.08 -0.289 -0.119 -0.066 0.175 . 0.084 . -0.228 . . . 0.069 0.254 0.529 0.005 -0.021 0.091 0.284 -0.059 -0.059 . . . . -0.256 -0.323 . 0.108 0.739 . . . . . 0.18 0.275 2.485 0.092 0.14 . . . . . -0.442 0.153 -0.018 0.203 -0.146 . -0.004

rs789252641 rs789834090 rs793481838 rs786861271 rs792030496 rs792500441 rs788100655 rs790450337 rs787683635 rs792634699 831062 rs7936 rs788438406 rs792083379 175907 rs7881 rs788196845 rs789843072 rs793547420 rs789562208 . rs790513826 . rs793185893 . . . 359982 rs7862 391661 rs7911 062936 rs7929 rs787703290 . rs791854810 . rs786736555 rs786541371 rs792036414 rs792777511 rs793810941 . 338028 rs7870 rs791498941 037325 rs7906 . rs786963284 rs786808150 rs790299824 rs791868246 002889 rs7902 809457 rs7901 981955 rs7933 rs788357200 rs792496486 461243 rs7885 461243 rs7885 rs793836431 rs713599403 935243 rs7873 . . rs786658083 rs793691100 858739 rs7899 514511 rs7865 rs792789795 314628 rs7924 827698 rs7893 rs791585417 185624 rs7875 rs786466500 rs792803571 . rs792351155 281174 rs7912 . 214072 rs7863 827679 rs7908 rs789738351 450223 rs7879 . 604892 rs7920 rs787472562 rs792650354 rs786367340 rs788694178 674274 rs7921

2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 5 2 2 2 2 2 4 2 2 4 2 2 2 2 2 2 2 2 2 3 2 2 4 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 5 2 2 2 2 2 2 3 2 2 2 2 4 2 2 2 3 2 2 2 2 4 2 2 2 2 2 2

AC.GT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AAG.CTT AAAAC.GTTTT AAAAC.GTTTT AAAC.GTTT AAATC.GATTT AG.CT AAAAAC.GTTTTT AT.AT AAAC.GTTT AAAAC.GTTTT AT.AT AAAT.ATTT AC.GT AAAC.GTTT AAAC.GTTT AAAC.GTTT AATT.AATT AAAC.GTTT AAAC.GTTT AAT.ATT AAAAC.GTTTT ACC.GGT AT.AT AAAT.ATTT AC.GT AC.GT AAGG.CCTT AC.GT AAAC.GTTT AG.CT AAAC.GTTT AC.GT AATG.CATT AAAC.GTTT AAAAC.GTTTT AAT.ATT AAAC.GTTT AAAC.GTTT AAAAG.CTTTT AGC.GCT AG.CT AG.CT AG.CT AAAAC.GTTTT ATCC.GGAT AAAC.GTTT AAC.GTT AG.CT AG.CT AAAC.GTTT AAC.GTT AC.GT ACAT.ATGT AT.AT AAAT.ATTT AAAC.GTTT AT.AT AAAC.GTTT AAC.GTT ATC.GAT AT.AT AAAC.GTTT AC.GT AC.GT AAAT.ATTT ATC.GAT AACAGT.ACTGTT AC.GT AAAC.GTTT AAT.ATT AAAC.GTTT AC.GT AG.CT AC.GT AAG.CTT AAAC.GTTT AAC.GTT AT.AT AC.GT AC.GT

13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13

83409746 83446694 83587504 83677560 84183182 84277344 84582171 84621035 84993461 85046287 85059932 85079479 85225842 85238798 85242521 85551837 85733328 85753086 85849666 85955109 86162027 86164736 86317101 86675562 86748699 86952825 86974857 87707094 87750073 88016142 88424832 88484285 88495417 88531723 88569210 88660362 88788458 89024381 89077381 89166103 89342727 89402502 89553956 89565530 89616104 89616104 89616104 89685931 89800614 89932661 89968783 90035741 90308822 90361168 90371830 90499600 90660474 90686315 90733627 90910803 91024055 91168383 91263290 91361588 91408276 91476357 91645543 91651231 91779415 91950711 92077128 92202203 92232917 92439574 92669253 92831955 93063159 93287819 93392922 93427507 93491659 93516600 93668819 93686785

83409758 83446712 83587522 83677586 84183219 84277362 84582199 84621046 84993479 85046298 85059950 85079489 85225860 85238816 85242535 85551859 85733348 85753119 85849680 85955129 86162044 86164750 86317126 86675582 86748715 86952840 86974869 87707113 87750091 88016158 88424858 88484309 88495430 88531738 88569228 88660373 88788486 89024399 89077396 89166118 89342741 89402516 89553991 89565545 89616114 89616114 89616114 89685956 89800642 89932684 89968804 90035758 90308834 90361191 90371870 90499611 90660489 90686324 90733641 90910822 91024072 91168397 91263304 91361602 91408286 91476375 91645584 91651250 91779433 91950731 92077159 92202217 92232931 92439590 92669271 92831965 93063169 93287845 93392934 93427525 93491683 93516609 93668829 93686821

6.5 3.8 4.75 6.75 12.6667 3.8 5.8 3 3.8 6 3.16667 5.5 4.75 3.8 7.5 5.75 10.5 8.5 3.75 5.25 4.5 3.75 6.5 7 3.4 5.33333 6.5 5 9.5 8.5 6.75 12.5 3.5 8 4.75 6 7.25 4.75 3.2 5.33333 3.75 3.75 7.2 5.33333 5.5 5.5 5.5 5.2 7.25 6 7.33333 9 6.5 6 13.6667 6 4 5 3.75 5 9 3.75 5 5 5.5 4.75 21 10 4.75 7 5.33333 7.5 3.75 5.66667 4.75 5.5 5.5 13.5 4.33333 4.75 8.33333 5 5.5 18.5

. . ENSSSCT00000012749 . . . . ENSSSCT00000012757 ENSSSCT00000012754 ENSSSCT00000012754 ENSSSCT00000012754 ENSSSCT00000012754 . . . . . . . . . . . ENSSSCT00000012762 . ENSSSCT00000023265 ENSSSCT00000023265 . . . . . . . . . . . . ENSSSCT00000012771 . ENSSSCT00000012773 . . ENSSSCT00000030064 ENSSSCT00000012774 ENSSSCT00000021586 . . . . . . . . ENSSSCT00000012782 . . . ENSSSCT00000012784 ENSSSCT00000012786 ENSSSCT00000012787 ENSSSCT00000012789 ENSSSCT00000012791 . . . . ENSSSCT00000024870 ENSSSCT00000024870 ENSSSCT00000012794 ENSSSCT00000012794 ENSSSCT00000012794 . . . . . . . . . . .

. . . . . . . PCCB . . . . . . . . . . . . . . . . . CEP70 CEP70 . . . . . . . . . . . . CLSTN2 . TRIM42 . . SLC25A36 SLC25A36 snoU13 . . . . . . . . . . . . XRN1 ATR PLS1 TRPC1 PCOLCE2 . . . . . . . . . . . . . . . . . . . .

intergenic intergenic promoter intergenic intergenic intergenic intergenic intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intron intergenic intergenic intron intron promoter intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intron intron intron intron intron intergenic intergenic intergenic intergenic intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

-0.048 . 0.387 0.039 0.639 0.214 . . 0.106 . . 0.083 0.221 0.221 0.242 . -0.106 -0.016 0.194 . . 0.938 . 0.223 0.078 1.148 0.02 0.156 0.429 0.227 0.005 0.101 0.022 -0.057 0.05 0.232 -0.015 0.444 0.098 . . 0.089 . -0.102 -0.001 -0.001 -0.001 . 0.141 0.144 0.681 0.481 -0.018 . 0.239 . . 0.933 -0.001 1.559 0.235 0.313 . . 0.122 0.141 -0.02 -0.052 0.071 0.323 0.237 0.116 0.073 . 0.201 -0.085 -0.58 -0.006 -0.153 -0.098 0.001 . . 0.032

. rs792554614 rs792061168 rs792786960 . rs791785441 827029 rs7909 rs788636489 rs791218747 . 256474 rs7920 . 873146 rs7912 rs789399556 . rs792965579 rs789941590 784509 rs7872 rs789473158 rs787416508 rs792607108 rs791295750 rs789645413 rs788142371 934780 rs7935 263142 rs7893 rs791972279 069714 rs7913 . rs698980167 240880 rs7931 350340 rs7917 rs791396297 rs787116124 428928 rs7864 . rs786885058 rs790328009 rs790746502 . rs790070956 rs787502755 rs788806531 rs793396417 . . . rs787717808 227191 rs7936 216734 rs7883 235713 rs7868 . rs793498384 rs789950470 rs793888058 rs789769223 . rs791899573 rs789090883 rs792428307 rs789334603 . rs788175362 rs790276611 rs790799013 rs695024171 rs792419344 . . rs789042023 rs787637315 rs787506942 rs788529157 rs703710880 rs790584829 . . rs791429930 rs788978063 rs789601794 rs787392972 rs786920882 rs790468821 .

3 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 7 2 3 2 2 2 2 2 3 4 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 3 2 4 2 4 3 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 3 2 2 3 3 2 2 2 2 2 3

AAG.CTT AT.AT AC.GT AT.AT AC.GT ATC.GAT ATC.GAT AC.GT AAAC.GTTT AAAC.GTTT AAAT.ATTT AAAC.GTTT AAAC.GTTT AC.GT AAAAC.GTTTT AT.AT AT.AT AC.GT AAAAG.CTTTT AAT.ATT AGG.CCT AC.GT AT.AT AAAAC.GTTTT AAAAC.GTTTT AAC.GTT AAGC.GCTT AATG.CATT AAC.GTT ACAT.ATGT AC.GT AAAAG.CTTTT AC.GT AAAT.ATTT AAAT.ATTT AAT.ATT AT.AT AC.GT AC.GT AAAAC.GTTTT AAG.CTT AAAAC.GTTTT AC.GT AAC.GTT AAAT.ATTT AG.CT AAAC.GTTT AAAC.GTTT AC.GT AT.AT AAAAC.GTTTT AAG.CTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AAAAAT.ATTTTT AAAT.ATTT AAAAC.GTTTT AAC.GTT AC.GT AGGG.CCCT AT.AT AT.AT AAAT.ATTT AAAC.GTTT AAAAAC.GTTTTT AG.CT AATT.AATT AAAT.ATTT AAAC.GTTT AAAC.GTTT AT.AT AAAC.GTTT AAAC.GTTT AG.CT AG.CT AT.AT AAAT.ATTT AAAAC.GTTTT AC.GT AT.AT AATG.CATT AG.CT

13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13

94223493 94500039 94501685 94622522 94678460 94692366 95321166 95589370 95657831 95708304 96043730 96304155 96409003 96662275 96861412 96960641 96960641 98114656 98171159 98247217 98278197 98597788 98689160 98731433 98731433 98943235 99139451 99317028 99663649 99711413 99720108 99864451 99931117 99944830 99989335 100020177 100171414 100197935 100211900 100246331 100501796 100644662 100761073 100968179 101069996 101092237 101213987 101282129 101336308 101688092 101723363 101930451 102101672 102374342 102374342 102493612 102553299 102661899 102669466 102704558 102718545 102826124 102906032 102963974 103010913 103287420 103395404 103561467 103741311 103927942 104115063 104210745 104314401 104748272 104776291 104949441 105290920 105303909 105353537 106083206 106394767 106751717 106840502 107102539

94223507 94500053 94501704 94622540 94678476 94692382 95321186 95589382 95657855 95708324 96043749 96304189 96409017 96662298 96861448 96960656 96960656 98114672 98171187 98247232 98278211 98597804 98689170 98731460 98731460 98943252 99139474 99317044 99663668 99711444 99720123 99864469 99931128 99944843 99989350 100020190 100171424 100197947 100211913 100246359 100501812 100644688 100761092 100968210 101070016 101092246 101214009 101282143 101336327 101688103 101723390 101930465 102101698 102374370 102374370 102493634 102553318 102661917 102669483 102704578 102718555 102826140 102906042 102963987 103010938 103287439 103395431 103561478 103741329 103927969 104115081 104210769 104314412 104748292 104776304 104949452 105290930 105303924 105353560 106083233 106394785 106751728 106840525 107102555

5 7.5 10 9.5 8.5 5.66667 7 6.5 6.25 5.25 5 8.75 3.75 12 7.4 8 8 8.5 5.8 5.33333 5 8.5 5.5 5.6 5.6 6 6 4.25 6.66667 8 8 3.8 6 3.5 4 4.66667 5.5 6.5 7 5.8 5.66667 5.4 10 10.6667 5.25 5 5.75 3.75 10 6 5.6 5 6.75 7.25 7.25 4.6 3.33333 4.75 3.6 7 5.5 4.25 5.5 7 6.5 5 4.66667 6 4.75 7 4.75 6.25 6 5.25 3.5 6 5.5 8 6 5.6 9.5 6 6 8.5

ENSSSCT00000012797 PLOD2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000035119 AGTR1 intron ENSSSCT00000034453 AGTR1 intron ENSSSCT00000022374 RNF13 intron ENSSSCT00000022374 RNF13 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000030003 TSC22D2 intron ENSSSCT00000012818 TSC22D2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000012827 IGSF10 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000012830 MBNL1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000012832 RAP2B intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000027576 DHX36 intron ENSSSCT00000023601 DHX36 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000027200 SLC33A1 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000027152 . intron . . intergenic . . intergenic ENSSSCT00000024993 . intron ENSSSCT00000012836 VEPH1 intron ENSSSCT00000012836 VEPH1 intron ENSSSCT00000012836 VEPH1 intron ENSSSCT00000025053 SHOX2 intron ENSSSCT00000030951 . intron . . intergenic . . intergenic . . intergenic

-0.004 0.011 -0.062 -0.097 0.07 . -0.03 0.707 0.056 -0.091 -0.262 . -0.02 0.381 0.264 0.276 0.276 0.179 . 0.095 0.027 0.11 0.334 0.253 0.253 . 0.147 0.27 -0.125 -0.218 -0.026 . . 0.059 . 0.089 . -0.013 . . 0.108 -0.027 0.061 -0.275 0.005 0.096 . . . 0.025 -0.038 . . -0.055 -0.055 0.307 0.263 . . 0.144 0.016 . -0.219 0.147 0.263 0.417 0.261 0.001 0.197 0.251 0.58 . 0.018 -0.006 0.038 . 0.247 0.051 . 0.675 0.465 . -0.033 .

rs793366082 . . rs792811636 . rs787642696 711841 rs7892 rs792650624 118219 rs7912 rs792283550 rs793070054 258533 rs7880 rs787486474 393334 rs7936 795703 rs7886 rs791226358 rs791226358 . rs789672418 rs791052462 . rs792157493 rs789232657 rs788721684 rs788721684 rs789782396 783909 rs7932 rs786637988 rs792463131 772259 rs7882 813252 rs7867 rs790409434 . rs790129980 rs793820697 rs791736690 rs792904633 . rs786942442 786858 rs7867 rs788028937 069012 rs7925 rs792853589 rs791539892 rs792614520 . 435571 rs7876 . rs791796784 rs788142846 rs790340187 rs789186517 rs792934231 rs786751763 rs786751763 rs793657473 rs787460942 rs792694393 . rs793010317 rs786625468 rs792443788 rs793305148 . rs789090036 rs792138217 rs792980948 rs792563150 rs790585426 rs789226357 rs791098528 rs792656031 rs788011014 rs790809350 rs787171606 rs791614510 . . rs787928575 rs792821710 rs790114922 rs791720596 rs791213632 rs790112905

2 4 5 2 3 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 3 4 2 2 2 3 2 2 2 2 2 4 2 3 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 4 2 2 2 3 2 4 2 2 2 2 2 2 4 2 2 2 4 2 2 3

AAAG.CTTT AG.CT AAAC.GTTT AAAC.GTTT AC.GT AT.AT AAAC.GTTT AAAC.GTTT AG.CT AAAT.ATTT AAAC.GTTT AAC.GTT AT.AT AAT.ATT AAAT.ATTT AAAC.GTTT AT.AT AAAC.GTTT AG.CT AAAC.GTTT AAAG.CTTT AT.AT AAAAC.GTTTT AT.AT AC.GT AAAT.ATTT AT.AT AT.AT AC.GT AG.CT AG.CT AAC.GTT AATC.GATT AAAC.GTTT AAC.GTT AT.AT AAAC.GTTT AC.GT AT.AT AC.GT AC.GT AAAT.ATTT AAAAAT.ATTTTT AAAAT.ATTTT AG.CT AC.GT AT.AT AT.AT AC.GT AT.AT AG.CT ACTAT.ATAGT AT.AT AAAC.GTTT AC.GT AAAAT.ATTTT AT.AT AAT.ATT AG.CT AT.AT AAAAC.GTTTT ACAT.ATGT AAAC.GTTT AT.AT AAAC.GTTT AAC.GTT AAC.GTT AC.GT AC.GT AAATG.CATTT AC.GT AAAC.GTTT AC.GT AATG.CATT AAAAG.CTTTT AAAAC.GTTTT AC.GT AC.GT AAAAAT.ATTTTT AAAC.GTTT AAAC.GTTT AAC.GTT AAC.GTT AAAT.ATTT

13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13

107121143 107356280 107399680 107498666 107536938 107756509 107820545 107955136 107997559 108011306 108017582 108087899 108684956 109179431 109207148 109250690 109422859 109485440 109525191 109593400 109598521 109751279 110063107 110105536 110780330 110848577 111389934 111510711 111584310 111937897 111986963 112018107 112080497 112112328 112348479 112473487 112483537 112514175 112679362 112762236 112762236 112791651 112800426 113009972 113057640 113096583 113117345 113246286 113250244 113748731 114048040 114465225 114892571 114904949 115066551 115212633 115307415 115761554 116170768 116211173 116250305 116370713 116663391 116986260 117486241 117577815 117577815 117581998 117581998 117695069 117813639 118425912 118570920 118583925 118935359 119033297 119059799 119177905 119405015 119876823 119876823 119878516 119878516 119942603

107121165 107356290 107399704 107498681 107536969 107756519 107820562 107955152 107997569 108011323 108017603 108087912 108684965 109179449 109207167 109250711 109422879 109485454 109525203 109593424 109598544 109751288 110063131 110105551 110780349 110848597 111389950 111510723 111584326 111937921 111986973 112018121 112080519 112112340 112348504 112473497 112483567 112514189 112679374 112762246 112762246 112791662 112800453 113009993 113057652 113096597 113117376 113246300 113250254 113748741 114048051 114465251 114892584 114904963 115066567 115212655 115307425 115761571 116170785 116211182 116250328 116370727 116663408 116986279 117486259 117577828 117577828 117582007 117582007 117695107 117813649 118425939 118570931 118583946 118935376 119033319 119059813 119177916 119405032 119876846 119876846 119878532 119878532 119942619

5.75 5.5 6.25 4 16 5.5 4.5 4.25 5.5 4.5 5.5 4.66667 5 6.33333 5 5.5 10.5 3.75 6.5 6.25 6 5 5 8 10 5.25 8.5 6.5 8.5 12.5 5.5 5 5.75 3.25 8.66667 5.5 7.75 7.5 6.5 5.5 5.5 3 4.66667 4.4 6.5 7.5 16 7.5 5.5 5.5 6 5.4 7 3.75 8.5 4.6 5.5 6 9 5 4.8 3.75 4.5 10 4.75 4.66667 4.66667 5 5 7.8 5.5 7 6 5.5 3.6 4.6 7.5 6 3 6 6 5.66667 5.66667 4.25

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000012839QCJ-SCHIP intron . . intergenic . . intergenic . . intergenic ENSSSCT00000032569 . intron . . intergenic . . intergenic . . intergenic ENSSSCT00000024911 NMD3 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000032326 . intron ENSSSCT00000012846 SI intron ENSSSCT00000012846 SI intron ENSSSCT00000012846 SI intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000012848 SERPINI2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000027451 PHC3 intron ENSSSCT00000029926 PHC3 intron ENSSSCT00000027451 PHC3 intron ENSSSCT00000029926 PHC3 intron ENSSSCT00000012856 PKC promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000012861 PLD1 intron ENSSSCT00000012862 TMEM212 intron ENSSSCT00000032717 TNFSF10 intron ENSSSCT00000025711 TNFSF10 intron ENSSSCT00000032717 TNFSF10 intron ENSSSCT00000025711 TNFSF10 intron . . intergenic

0.237 -0.139 . -0.094 -0.107 -0.054 0.109 -0.134 . 0.134 0.097 -0.07 0.174 . . . 0.078 0.256 . 0.19 0.343 0.684 0.188 0.591 . . . 0.055 -0.042 . . . 0.104 -0.042 . -0.139 . -0.026 0.016 . . -0.411 0.541 -0.139 -0.034 0.056 . -0.116 0.06 -0.155 -0.216 -0.001 -0.114 0.542 0.122 0.252 . 0.062 -0.12 0.021 -0.052 -0.083 -0.056 1.03 . 0.208 0.208 0.269 0.269 0.333 0.094 0.356 0.22 0.173 0.058 0.093 . . -0.033 0.071 0.071 0.132 0.132 .

rs791464063 . rs787084423 241643 rs7929 . . rs788623457 . 547214 rs7915 932429 rs7887 rs793807983 rs787642274 rs788397120 . rs792303534 rs788276520 rs786688734 rs790814299 rs791394089 rs792571797 rs786911075 rs789324854 rs792269303 506736 rs7877 rs792036269 130273 rs7919 rs792574996 584116 rs7893 . 742434 rs7895 . . rs787030142 . rs792642979 rs786973025 rs786664261 290704 rs7879 . . . rs786953802 039880 rs7924 746755 rs7896 rs790512242 rs793189608 rs787246812 350294 rs7895 rs788306182 . rs708232354 rs793144495 671214 rs7932 rs790929373 rs789443203 . rs792665880 rs786403961 rs792756598 rs791701574 rs787147634 rs792515796 rs791072884 rs792186808 291156 rs7938 rs786912536 rs786912536 . . . rs790356292 rs792738519 . rs696016252 rs793627670 rs792358020 rs787642771 364904 rs7872 rs790645566 393336 rs7886 393336 rs7886 rs793024408 rs793024408 rs788195025

2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 3 2 2 2 2 2 2 3 5 2 4 2 2 2 2 2 2 2 3 3 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2

AT.AT AT.AT AAAC.GTTT AC.GT AC.GT AG.CT AG.CT AAT.ATT AT.AT ACC.GGT AAAAAG.CTTTTT AAAAAC.GTTTTT AAC.GTT AAAC.GTTT AAC.GTT AC.GT AG.CT AAAC.GTTT AT.AT AG.CT AATC.GATT AT.AT AAAC.GTTT AAC.GTT AAAAAG.CTTTTT AAC.GTT AAAG.CTTT AC.GT AAAC.GTTT AGC.GCT AG.CT AT.AT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AC.GT AAC.GTT AG.CT AT.AT AAC.GTT AT.AT AAAC.GTTT ACACAT.ATGTGT AT.AT AT.AT AAG.CTT AAG.CTT AAAT.ATTT AATC.GATT AAAATC.GATTTT AAAT.ATTT AT.AT AAC.GTT AC.GT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AC.GT AAACC.GGTTT AT.AT AT.AT AC.GT AAAT.ATTT AAT.ATT AAGG.CCTT AAAAT.ATTTT AAAAT.ATTTT AAC.GTT AC.GT AC.GT AAAAC.GTTTT AC.GT AC.GT AG.CT AC.GT AC.GT AC.GT AATG.CATT AATG.CATT AAC.GTT AAAT.ATTT AAC.GTT AC.GT

13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13

119975726 120180940 120261803 120639395 120686315 120784799 120818340 121219370 121295031 121310641 121341970 121497017 121668771 121697134 121883546 121896331 122027241 122520749 122792084 122822063 122853256 122854733 123114005 123278462 123285637 123352048 123649881 123911817 123927818 124253148 124504948 124521424 124660839 125133918 125171216 125366980 125524022 125904034 125924036 125996320 126007610 126206451 126241107 126742251 126930210 126963303 127163765 127213121 127335764 127461748 127479934 127521978 127652543 127822043 127827950 128102344 128102344 128102344 129037773 129063729 129486712 129703643 129851225 130321916 130472086 130554696 130966135 131034758 131239859 131279363 131299173 131555759 131561974 131632998 131798573 131961865 132269857 132282470 132319820 132319820 132598580 132681196 133161636 133188493

119975746 120180949 120261822 120639429 120686334 120784808 120818349 121219395 121295043 121310654 121341991 121497052 121668793 121697152 121883564 121896340 122027254 122520775 122792094 122822075 122853285 122854746 123114027 123278489 123285654 123352064 123649893 123911829 123927842 124253162 124504957 124521435 124660877 125133936 125171249 125366994 125524035 125904044 125924048 125996333 126007626 126206468 126241148 126742260 126930220 126963325 127163779 127213148 127335783 127461767 127479948 127521987 127652571 127822059 127827979 128102358 128102358 128102358 129037788 129063766 129486724 129703663 129851235 130321944 130472103 130554730 130966157 131034792 131239874 131279377 131299185 131555791 131561984 131633010 131798589 131961887 132269866 132282481 132319850 132319850 132598594 132681212 133161651 133188502

10.5 5 5 17.5 10 5 5 8.66667 6.5 4.66667 3.66667 6 7.66667 4.75 6.33333 5 7 6.75 5.5 6.5 7.5 7 5.75 9.33333 3 5.66667 3.25 6.5 6.25 5 5 6 9.75 4.75 6.8 7.5 4.66667 5.5 6.5 4.66667 8.5 4.5 7 5 5.5 7.66667 5 7 5 3.33333 3.75 5 9.66667 8.5 7.5 3.75 3.75 3.75 8 7.6 6.5 10.5 5.5 7.25 6 8.75 4.6 7 5.33333 7.5 6.5 6.6 5.5 6.5 8.5 11.5 5 6 7.75 7.75 5 4.25 5.33333 5

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000026159 NAALADL2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000012874 MRPL47 intron . . intergenic ENSSSCT00000012877 PEX5L intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000012878 TTC14 intron . . intergenic ENSSSCT00000027605 FXR1 intron ENSSSCT00000027021 FXR1 intron ENSSSCT00000012881 FXR1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000012887 KLHL24 intron ENSSSCT00000012891 PARL intron ENSSSCT00000012892 . intron ENSSSCT00000012893 . promoter . . intergenic . . intergenic ENSSSCT00000024405 PSMD2 intron . . intergenic ENSSSCT00000023583 EPHB3 intron ENSSSCT00000012900 . intron ENSSSCT00000012900 . intron ENSSSCT00000012900 . intron ENSSSCT00000024055 . intron . . intergenic ENSSSCT00000024873 EHHADH intron . . intergenic . . intergenic

. . . . -0.153 -0.075 0.028 -0.069 . 0.01 -0.272 0.012 0.695 0.141 0.121 0.122 . 0.049 0.027 0.204 0.213 -0.21 0.11 . -0.002 . -0.035 . . -0.193 -0.005 0.023 0.095 0.141 . 0.132 . . 0.037 0.278 -0.162 0.089 0.191 0.194 1.591 . 0.294 . 0.25 0.285 -0.171 0.153 0.356 -0.151 0.297 0.12 0.12 0.12 0.15 0.298 0.373 0.221 . . 0.3 . . . . 0.209 -0.11 . . 2.544 . 0.222 0.121 0.318 1.366 1.366 . 0.351 . -0.192

. . 698737 rs7897 rs793813400 rs788684324 . . rs790738475 076764 rs7863 . rs792584036 805784 rs7905 rs786884213 rs790778976 rs787038629 rs791388723 rs792172764 rs787512344 rs786807495 rs792434871 rs791403288 rs787327342 rs792705176 rs787130627 rs790779402 rs792221827 rs789359651 rs788518138 rs790713979 rs790396244 rs786669639 rs789120604 rs793568017 rs790723897 774173 rs7904 600109 rs7869 . . rs793428464 rs788469901 351534 rs7905 rs791468118 rs787176727 rs789124362 rs789657565 rs787535207 . . rs788930436 rs788240153 rs788574207 rs792663588 rs790112653 rs787291697 rs791880697 rs792271396 rs792271396 rs792271396 . rs791808672 rs790052494 rs786718245 . . rs792273139 rs793175875 rs789731998 . . rs790657095 248674 rs7927 940599 rs7921 rs788915122 rs792578807 rs788012927 . rs786893416 rs787021117 rs792621711 rs792621711 . rs787772567 rs786338350 rs787311838

2 3 3 3 2 3 3 2 2 2 2 2 2 5 2 2 2 2 2 2 2 3 2 4 2 2 4 4 2 2 2 2 3 2 3 4 5 3 2 2 3 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 4 2 6 2 2 2 2 2 2 2 5 2 2 2 2 2 2 2 2 3 2 2 3 2 2 2

AC.GT AG.CT AC.GT AAAC.GTTT AAAAC.GTTTT AATG.CATT AT.AT AAAAAG.CTTTTT AAC.GTT AC.GT AAAC.GTTT AAAAC.GTTTT AG.CT AT.AT AG.CT AG.CT AC.GT AAAC.GTTT AT.AT AT.AT AT.AT AAAT.ATTT AAAT.ATTT AG.CT AC.GT AG.CT AG.CT AAAC.GTTT AAG.CTT AAG.CTT AAAAT.ATTTT AT.AT AG.CT AAAT.ATTT AC.GT AAAAC.GTTTT AC.GT AT.AT AC.GT AT.AT AAAT.ATTT AG.CT AC.GT AT.AT AG.CT AAAAT.ATTTT AT.AT ACAG.CTGT ATC.GAT AG.CT AG.CT AAC.GTT AT.AT AAAT.ATTT AC.GT AAAC.GTTT AAGG.CCTT AAAT.ATTT AAAAC.GTTTT AC.GT AC.GT AAAC.GTTT AAAAT.ATTTT AC.GT AGAGG.CCTCT AAAC.GTTT AT.AT AG.CT AAAC.GTTT AAAAC.GTTTT AATG.CATT ACAG.CTGT AAAAT.ATTTT AG.CT AAAAT.ATTTT AC.GT AG.CT AAC.GTT AAC.GTT AAC.GTT AAAC.GTTT AGG.CCT AAC.GTT AC.GT

13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13

133459799 133734300 133743610 134015870 134144433 134150450 134394341 134409793 134456468 134612007 134988391 135029061 135127252 135198265 135769869 135784246 135830244 135927635 136354209 136360218 136361212 136373033 136756941 136783404 136826938 136864967 136900863 137527098 137626597 137626597 137686253 137714086 137771377 137867229 138021424 138047026 138292995 138360831 138528131 138545691 138589260 138633750 138778830 138938693 139009543 139010395 139134083 139155024 139687826 139722928 139724373 139732841 139893792 139903906 140210010 140215587 140223436 140536540 140609956 140726174 140873369 140994605 141144459 141185431 141271842 141279582 141304003 141355537 141496653 141644694 141719591 142058289 142109883 142166196 142178470 142192310 142312085 142450287 142450287 142450287 142692703 142791558 142853788 142930813

133459828 133734316 133743621 134015892 134144452 134150480 134394350 134409821 134456483 134612016 134988408 135029087 135127264 135198276 135769880 135784271 135830257 135927663 136354224 136360227 136361227 136373051 136756959 136783416 136826952 136864977 136900875 137527128 137626614 137626614 137686272 137714095 137771388 137867248 138021443 138047046 138293012 138360841 138528142 138545702 138589287 138633767 138778855 138938708 139009554 139010414 139134092 139155037 139687846 139722941 139724384 139732860 139893823 139903923 140210028 140215609 140223457 140536556 140609984 140726185 140873386 140994627 141144476 141185443 141271865 141279600 141304012 141355549 141496676 141644719 141719621 142058302 142109907 142166210 142178489 142192334 142312099 142450303 142450303 142450303 142692726 142791574 142853803 142930825

15 8.5 6 5.75 4 7.75 5 4.83333 5.33333 5 4.5 5.4 6.5 6 6 13 7 7.25 8 5 8 4.75 4.75 6.5 7.5 5.5 6.5 7.75 6 6 4 5 6 5 10 4.2 9 5.5 6 6 7 9 13 8 6 4 5 3.5 7 7 6 6.66667 16 4.5 9.5 5.75 5.5 4.25 5.8 6 9 5.75 3.6 6.5 4.8 4.75 5 6.5 6 5.2 7.75 3.5 5 7.5 4 12.5 7.5 5.66667 5.66667 5.66667 6 5.66667 5.33333 6.5

ENSSSCT00000024619 . . . . . ENSSSCT00000012917 . . . ENSSSCT00000026129 ENSSSCT00000026129 ENSSSCT00000026129 ENSSSCT00000026129 . . . . . . . . ENSSSCT00000012925 ENSSSCT00000012925 ENSSSCT00000012925 . . . ENSSSCT00000031033 ENSSSCT00000027738 . . . . . ENSSSCT00000012929 . . . . . . ENSSSCT00000023418 ENSSSCT00000023418 . . . . . . . . ENSSSCT00000031000 ENSSSCT00000031000 ENSSSCT00000012934 ENSSSCT00000012934 ENSSSCT00000012934 . . . . ENSSSCT00000012937 . ENSSSCT00000012938 . . . . . . . . . . . . . ENSSSCT00000034060 ENSSSCT00000012945 ENSSSCT00000033279 . . ENSSSCT00000012953 ENSSSCT00000012955

DGKG . . . . . RTP1 . . . . . . . . . . . . . . . LEPREL1 LEPREL1 LEPREL1 . . . GMNC GMNC . . . . . CCDC50 . . . . . . FGF12 FGF12 . . . . . . . . ATP13A5 ATP13A5 OPA1 OPA1 OPA1 . . . . ATP13A3 . TMEM44 . . . . . . . . . . . . . DLG1 DLG1 DLG1 . . SENP5 .

intron intergenic intergenic intergenic intergenic intergenic promoter intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intergenic intergenic intergenic intergenic intron intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intron intron

-0.051 . -0.229 -0.035 -0.012 0.121 -0.016 . . 0.058 0.037 . -0.145 -0.018 0.081 0.077 0.334 -0.034 0.092 0.85 . -0.008 . -0.274 -0.153 -0.099 -0.206 -0.056 0.467 0.467 . . . . 0.344 . 0.308 -0.185 . 0.032 0.024 0.014 . -0.127 0.119 0.073 0.051 0.027 . -0.009 0.043 0.06 0.404 -0.001 0.223 0.073 0.029 0.16 0.192 1.113 -0.171 0.129 . 0.123 0.52 0.217 . -0.132 0.12 . -0.147 0.248 0.554 0.142 0.003 -0.18 0.089 . . . . . 0.152 0.041

. rs791765889 rs792006591 rs789797566 rs793858143 430446 rs7916 rs786672394 rs788982483 rs789654620 . rs786337215 689136 rs7888 rs698227816 rs788135865 rs790652703 rs789471454 . rs787611826 . rs787012219 rs789903405 . rs788834472 rs789974312 rs791568582 rs792998124 759088 rs7875 rs787917532 rs793620339 rs793620339 rs791898150 . 357577 rs7876 rs789619657 rs787678322 . rs787517496 rs709617218 rs791816415 . rs792402764 rs793518551 268595 rs7865 rs786606950 rs789916304 rs788600753 rs790934105 rs789854648 rs792304406 rs792628484 . rs786803869 . rs791164603 528844 rs7899 rs789471023 910921 rs7872 rs793068272 rs793667527 rs789724059 rs790801237 rs788348379 975044 rs7879 rs786784052 602734 rs7886 rs787324582 rs791348176 rs787486498 335428 rs7934 rs790714713 650182 rs7928 rs789340117 rs790353432 rs789232144 rs787425972 rs788991606 rs786911351 rs788547417 rs788547417 rs788547417 rs791195127 rs792097994 rs793863528 477736 rs7938

2 2 3 2 2 2 3 2 2 2 2 2 3 2 3 2 3 4 4 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 5 2 2 2 4 4 2 2 3 3 2 2 2 2 3 2 2 3 4 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2

AAT.ATT AAAAC.GTTTT AC.GT AC.GT AC.GT AAAAC.GTTTT AGGC.GCCT AAC.GTT AAAG.CTTT AAAG.CTTT AAAAC.GTTTT AAAAC.GTTTT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AG.CT AT.AT AT.AT AG.CT AAAC.GTTT AAAT.ATTT AAAT.ATTT AAAAAG.CTTTTT AAAC.GTTT AAAAC.GTTTT ATC.GAT AAAT.ATTT AT.AT AGG.CCT AAAAT.ATTTT AAAC.GTTT AAAGG.CCTTT AT.AT AT.AT AC.GT AC.GT AC.GT AC.GT AC.GT AC.GT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAC.GTT AAC.GTT AT.AT AAGG.CCTT AAAC.GTTT AAC.GTT AAAC.GTTT AAG.CTT AAAT.ATTT AAC.GTT AT.AT AAAC.GTTT AAC.GTT AAAC.GTTT AT.AT AT.AT AT.AT AT.AT AAAT.ATTT AC.GT AC.GT AC.GT ACAT.ATGT AT.AT AAAC.GTTT AC.GT AC.GT AAAC.GTTT AT.AT AC.GT AT.AT AC.GT ACAT.ATGT AATG.CATT AAT.ATT AG.CT AAC.GTT

13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13

143073994 143177138 143627339 143739728 143836549 143997771 144104670 144175430 144591312 144678474 145055246 145129233 145129233 145169844 145190513 145291425 145461833 145461833 145946976 145960014 146172486 146181176 146655987 147250196 147331504 147438046 147489070 147527557 147621806 147766094 147774497 147914053 148003591 148035260 148076877 148076877 148076877 148076877 148076877 148076877 148083231 148083231 148083231 148083231 148083231 148083231 148083231 148326723 148539457 148570084 149118429 149251682 149313625 149329403 149373063 149475743 149894909 150021411 150103149 150361287 150617008 150693668 150708276 150954994 151318004 151396601 151867762 152048102 152204542 152797969 152808638 152961942 153239777 153308795 153622839 153712761 153739483 153904957 153947288 154016772 154305306 154318192 154898781 154943397

143074008 143177155 143627349 143739741 143836558 143997796 144104692 144175448 144591327 144678492 145055266 145129261 145129261 145169870 145190526 145291435 145461842 145461842 145946988 145960028 146172498 146181196 146656013 147250210 147331528 147438060 147489087 147527566 147621819 147766109 147774513 147914075 148003602 148035272 148076894 148076894 148076894 148076894 148076894 148076894 148083249 148083249 148083249 148083249 148083249 148083249 148083249 148326734 148539476 148570095 149118443 149251705 149313639 149329420 149373080 149475770 149894934 150021423 150103167 150361298 150617023 150693678 150708292 150955004 151318014 151396622 151867773 152048112 152204559 152797987 152808651 152961968 153239787 153308809 153622863 153712772 153739497 153904983 153947317 154016794 154305334 154318211 154898792 154943413

5 3.6 5.5 7 5 5.2 5.75 6.33333 4 4.75 4.2 5.8 5.8 6.75 3.5 5.5 5 5 6.5 3.75 3.25 5.25 4.5 3.75 5 5 4.5 5 4.66667 3.2 4.25 4.6 6 6.5 9 9 9 9 9 9 4.75 4.75 4.75 4.75 4.75 4.75 4.75 4 6.66667 6 3.75 6 5 4.5 6 7 8.66667 6.5 4.75 4 4 5.5 8.5 5.5 5.5 5.5 6 5.5 9 4.75 7 6.75 5.5 7.5 6.25 6 7.5 13.5 15 5.75 7.25 6.66667 6 5.66667

ENSSSCT00000023388 . . . ENSSSCT00000012962 . ENSSSCT00000012966 ENSSSCT00000012968 . ENSSSCT00000012973 . ENSSSCT00000012978 ENSSSCT00000027472 ENSSSCT00000023434 ENSSSCT00000023434 ENSSSCT00000023434 ENSSSCT00000029280 ENSSSCT00000023434 . . . . ENSSSCT00000029344 . . ENSSSCT00000012988 . ENSSSCT00000012989 . ENSSSCT00000030693 ENSSSCT00000030693 ENSSSCT00000012993 . . ENSSSCT00000012992 ENSSSCT00000036378 ENSSSCT00000034076 ENSSSCT00000033968 ENSSSCT00000012991 ENSSSCT00000034541 ENSSSCT00000012992 ENSSSCT00000036378 ENSSSCT00000034076 ENSSSCT00000033968 ENSSSCT00000012991 ENSSSCT00000034541 ENSSSCT00000034788 ENSSSCT00000012997 . . . . ENSSSCT00000013005 ENSSSCT00000013005 . ENSSSCT00000013006 . . ENSSSCT00000013023 . . . . . . . . . . . . . ENSSSCT00000021219 . ENSSSCT00000030211 ENSSSCT00000030211 ENSSSCT00000030211 . . . . . . .

CEP19 . . . MUC4 . LRCH3 IQCG . SLC12A8 . UMPS UMPS . . . . . . . . . ADCY5 . . PARP14 . PARP15 . CCDC58 CCDC58 CASR . . CD86 CD86 CD86 CD86 CD86 CD86 CD86 CD86 CD86 CD86 CD86 CD86 CD86 IQCB1 . . . . GPR156 GPR156 . GSK3B . . TMEM39A . . . . . . . . . . . . . SNORD12 . LSAMP LSAMP LSAMP . . . . . . .

3'utr intergenic intergenic intergenic intron intergenic intron intron intergenic intron intergenic intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intron intergenic intergenic intron intergenic intron intergenic intron intron intron intergenic intergenic intron intron intron intron intron intron intron intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intron intron intergenic intron intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic promoter intergenic intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic

2.103 . 0.25 0.08 -0.164 -0.087 0.728 . 0.258 0.187 -0.061 . . . 0.177 . 0.017 0.017 0.334 -0.153 0.117 . 0.103 . 0.082 . . -0.22 0.137 0.193 0.277 0.149 . . 0.217 0.217 0.217 0.217 0.217 0.217 0.116 0.116 0.116 0.116 0.116 0.116 0.116 . . . 0.299 0.249 0.356 . 0.213 . . 0.098 0.047 . 0.017 0.357 1.38 . 0.086 0.014 1.072 0.232 -0.112 -0.075 0.6 -0.088 -0.197 0.155 . . 0.339 . 0.143 . 0.222 . 1.265 0.393

rs787893637 rs791771041 rs699935854 rs788174837 . 674002 rs7898 rs790765043 rs791332749 rs789586877 rs793270485 rs787102930 rs786225280 rs786225280 rs791065965 . rs790370032 . . rs789325940 rs786573524 rs792250699 rs790864816 rs786979273 109542 rs7874 rs792631141 rs788994819 336254 rs7908 rs792600023 rs790038331 rs691169158 rs787959677 rs786937055 . rs793053275 rs791900845 rs791900845 rs791900845 rs791900845 rs791900845 rs791900845 rs788596982 rs788596982 rs788596982 rs788596982 rs788596982 rs788596982 rs788596982 rs790725308 440389 rs7881 rs787269734 rs791311114 rs788647036 rs791623059 827338 rs7895 175357 rs7911 rs786974269 rs787055834 rs792989684 rs792128773 . rs787979579 . rs791831087 rs712127282 366683 rs7867 rs788454805 . . 755740 rs7871 . rs786280746 rs792070512 . . . rs787696803 rs786357110 rs696175118 rs699793355 rs792635342 894868 rs7899 rs789434079 rs788641945 332922 rs7868

3 2 4 2 4 2 2 2 3 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 3 3 3 3 3 3 3 2 2 2 2 2 2 2 2 2 2 2 2 3 4 2 3 3 3 2 2 2 3 4 2 2 2 2 2 2 2 3 4 2 2 2 2 2

AAC.GTT AAT.ATT AC.GT AAT.ATT AAAG.CTTT AT.AT AAT.ATT AC.GT AC.GT AAC.GTT AAAC.GTTT ACC.GGT AAC.GTT AAT.ATT AAT.ATT AAG.CTT AC.GT AAAAG.CTTTT AC.GT AAAAG.CTTTT AAAAG.CTTTT AT.AT AG.CT AAC.GTT AG.CT AAAT.ATTT AAG.CTT AAAC.GTTT AAAC.GTTT AAAAT.ATTTT AG.CT AT.AT AAAT.ATTT AAAT.ATTT AC.GT AAAT.ATTT AAC.GTT AC.GT AAAG.CTTT AGG.CCT AAAT.ATTT ACCT.AGGT AT.AT AAAC.GTTT AAG.CTT AAAAC.GTTTT AAAC.GTTT AAC.GTT AAC.GTT AAGG.CCTT AAAC.GTTT AC.GT ATC.GAT AT.AT AAAAC.GTTTT AAAAAG.CTTTTT AT.AT AAGG.CCTT AT.AT AT.AT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAG.CTT AAAC.GTTT AGAT.ATCT AAAC.GTTT AAAC.GTTT AC.GT AT.AT AT.AT AGG.CCT AC.GT AT.AT AAAC.GTTT AAT.ATT AAC.GTT AAC.GTT AT.AT AAAC.GTTT AAAT.ATTT AC.GT AAAAC.GTTTT AC.GT

13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13

155027825 155348367 155534032 155560966 155766722 155769527 156235908 156934258 157474396 157637754 157716108 157771634 157972944 158043035 158081632 158806181 158920709 159002448 159082620 159275738 159275738 159313066 159830276 159954451 160108386 160110786 160189915 160321123 160409508 160513422 160544654 160683677 160695791 160782423 160814541 161062984 161154826 161162491 161472337 161556855 161559694 161897561 161958460 162051542 162141772 162547865 162706954 162726972 163328634 163443520 163662165 163684540 163853861 163887139 163947372 163967058 163975536 164152034 164179286 164252760 164269080 164371706 164541418 164559987 164564030 164566557 164601685 164611175 164872284 164996689 165042092 165091901 165272797 165282781 165406862 165411436 165684375 165881342 165913500 165940639 166234697 166459971 166740307 166994230

155027839 155348386 155534048 155560979 155766735 155769536 156235924 156934276 157474420 157637767 157716119 157771650 157972970 158043061 158081662 158806192 158920719 159002464 159082630 159275769 159275769 159313079 159830286 159954466 160108402 160110833 160189947 160321142 160409535 160513449 160544666 160683689 160695816 160782438 160814555 161063002 161154842 161162501 161472353 161556869 161559719 161897583 161958472 162051562 162141786 162547892 162706969 162726990 163328654 163443535 163662187 163684549 163853882 163887150 163947398 163967077 163975547 164152077 164179296 164252769 164269104 164371721 164541447 164560002 164564048 164566595 164601703 164611210 164872299 164996708 165042103 165091919 165272809 165282793 165406880 165411449 165684388 165881373 165913520 165940661 166234722 166459983 166740330 166994240

5 6.66667 8.5 4.66667 3.5 5 5.66667 9.5 12.5 4.66667 3 5.66667 9 9 10.3333 4 5.5 3.4 5.5 6.4 6.4 7 5.5 5.33333 8.5 12 11 5 7 5.6 6.5 6.5 6.5 4 7.5 4.75 5.66667 5.5 4.25 5 6.5 5.75 6.5 5.25 5 5.6 4 6.33333 7 4 5.75 5 7.33333 6 5.4 3.33333 6 11 5.5 5 6.25 4 7.5 5.33333 4.75 9.75 4.75 9 8 10 6 6.33333 6.5 6.5 4.75 4.66667 4.66667 10.6667 10.5 5.75 6.5 6.5 4.8 5.5

. . intergenic ENSSSCT00000013034 . intron ENSSSCT00000013036 . intron ENSSSCT00000013036 . intron ENSSSCT00000013040 ATP6V1A intron ENSSSCT00000013040 ATP6V1A intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000013059 . intron ENSSSCT00000013058 PLCXD2 intron . . intergenic ENSSSCT00000031200 DPPA4 intron ENSSSCT00000027112 DPPA4 intron . . intergenic . . intergenic ENSSSCT00000013065 DZIP3 intron ENSSSCT00000027252 MYH15 intron ENSSSCT00000027252 MYH15 intron ENSSSCT00000027252 MYH15 intron . . intergenic . . intergenic ENSSSCT00000013068 CD47 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000013069 . intron ENSSSCT00000013069 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000023448 CBLB intron ENSSSCT00000023448 CBLB intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000032455 . intron

0.652 . 0.724 . 0.297 0.141 0.009 . -0.007 0.863 . . . -0.098 0.063 -0.123 -0.042 0.336 0.113 1.16 1.16 . -0.264 0.36 . . . 0.382 0.206 0.055 -0.078 0.219 . 0.316 0.156 0.325 0.238 0.113 . 0.872 0.127 -0.01 -0.033 . 0.224 0.029 0.208 0.211 . 0.084 -0.193 0.095 -0.093 -0.037 0.239 -0.102 . -0.048 -0.005 0.147 . -0.081 -0.112 -0.246 0.018 0.116 . . -0.158 -0.794 . . -0.069 -0.123 0.027 0.035 0.103 0.609 -0.1 0.167 0.157 0.179 0.102 .

rs786823913 rs791675414 rs786744009 rs792161369 rs788858587 rs792942614 341520 rs7916 . 176408 rs7916 rs793211901 469038 rs7934 . 913156 rs7868 rs789535702 205113 rs7899 643761 rs7936 . 830656 rs7883 . rs788466515 rs788466515 rs791748282 rs792844859 rs792296243 . 925848 rs7891 rs793582277 rs787184927 rs788900157 419380 rs7893 493601 rs7917 rs787859164 rs791651928 rs791156694 . 748752 rs7905 rs792185447 498190 rs7870 358713 rs7887 rs789205550 rs792272132 261995 rs7897 368608 rs7934 rs789681176 rs792238671 rs787095509 rs789067102 718077 rs7924 641565 rs7874 rs790592012 rs790541607 rs786954588 rs789411713 . 269576 rs7933 rs787190325 rs711374830 rs792804608 953214 rs7874 rs786300329 rs791689337 rs789621187 rs788781691 rs787841569 228210 rs7913 rs697092002 337343 rs7862 956820 rs7878 . rs787828684 rs786714749 rs791749649 rs789846434 . rs790289507 rs793275597 . rs788256489 rs787176383 941470 rs7908 rs791926704 230905 rs7911 rs786817495 rs793426165

2 2 3 2 2 2 3 2 3 2 2 2 2 2 2 2 3 2 2 2 2 4 2 2 4 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 4 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 4 2 2 4 2 2 2 2 3 2 3

AG.CT AG.CT AT.AT AAAC.GTTT AAAT.ATTT AAAT.ATTT AT.AT AC.GT AC.GT AC.GT AC.GT AC.GT AC.GT AC.GT AT.AT AAAC.GTTT AAAC.GTTT AC.GT AC.GT AAAG.CTTT AAAT.ATTT AAC.GTT AATT.AATT AT.AT AC.GT AAAAG.CTTTT AAAC.GTTT AAAC.GTTT AAAAT.ATTTT AAAC.GTTT AAG.CTT AAAAAT.ATTTTT AT.AT AG.CT AAAAG.CTTTT AT.AT AAT.ATT AAACC.GGTTT AAAT.ATTT AAAC.GTTT AAAT.ATTT AAAC.GTTT AG.CT AAAG.CTTT AC.GT AT.AT AG.CT AAC.GTT AAAAC.GTTTT AT.AT AT.AT AC.GT AAAAT.ATTTT AAGC.GCTT AC.GT AAAG.CTTT AC.GT AC.GT AG.CT AG.CT AAT.ATT AAAT.ATTT AC.GT AC.GT AATG.CATT AT.AT AAAC.GTTT AT.AT AACT.AGTT AAAC.GTTT AC.GT AAAAC.GTTTT ACAT.ATGT AAAT.ATTT AT.AT AT.AT AAAC.GTTT AATT.AATT AAAC.GTTT AAAC.GTTT AG.CT AAGG.CCTT AC.GT AG.CT

13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13

166995067 167075180 167113665 167165438 167418393 167428811 167441552 167554799 167567178 167599518 167702326 167818135 168101607 168262494 168451131 168490392 168994126 169218953 169750579 169965337 170101700 170116315 170326156 170358493 170407659 170488620 170839623 170849056 170876561 171009845 172054849 172085437 172086787 172117459 172169401 172330565 172585699 172589411 172600913 172987201 173111418 173397982 173439583 173610590 173613279 173725002 173956726 174067340 174079262 174176462 174328263 174421629 174593187 174788714 174796616 175020246 175027241 175086213 175324466 175368524 175537984 175543232 175580072 175832274 176089746 176704777 176785169 177398847 177509216 177700784 177737271 178092405 178349598 178354087 178820371 179313362 180017939 180029841 180137870 180269532 180280587 180320261 180385452 180419076

166995078 6 ENSSSCT00000032455 . intron 167075191 6 ENSSSCT00000022387 SENP7 intron 167113676 6 ENSSSCT00000022387 SENP7 intron 167165464 6.75 . . intergenic 167418420 7 . . intergenic 167428828 4.5 . . intergenic 167441561 5 . . intergenic 167554811 6.5 . . intergenic 167567192 7.5 . . intergenic 167599546 14.5 . . intergenic 167702337 6 . . intergenic 167818155 10.5 ENSSSCT00000013085 . intron 168101637 15.5 ENSSSCT00000013092 . intron 168262507 7 . . intergenic 168451144 7 . . intergenic 168490410 4.75 ENSSSCT00000013098 CMSS1 intron 168994140 3.75 . . intergenic 169218968 8 . . intergenic 169750591 6.5 . . intergenic 169965369 8.25 . . intergenic 170101725 6.5 . . intergenic 170116328 4.66667 . . intergenic 170326170 3.75 . . intergenic 170358503 5.5 ENSSSCT00000013106 DCBLD2 intron 170407688 15 . . intergenic 170488638 3.8 . . intergenic 170839651 7.25 . . intergenic 170849077 5.5 . . intergenic 170876581 4.2 . . intergenic 171009867 5.75 . . intergenic 172054864 5.33333 . . intergenic 172085460 4 . . intergenic 172086797 5.5 . . intergenic 172117477 9.5 . . intergenic 172169419 3.8 . . intergenic 172330574 5 . . intergenic 172585719 7 . . intergenic 172589433 4.6 . . intergenic 172600936 6 . . intergenic 172987223 5.75 . . intergenic 173111437 5 . . intergenic 173398004 5.75 . . intergenic 173439594 6 . . intergenic 173610608 4.75 . . intergenic 173613288 5 . . intergenic 173725016 7.5 . . intergenic 173956746 10.5 . . intergenic 174067353 4.66667 . . intergenic 174079286 5 . . intergenic 174176476 7.5 . . intergenic 174328276 7 . . intergenic 174421651 11.5 . . intergenic 174593205 3.8 . . intergenic 174788734 5.25 . . intergenic 174796628 6.5 . . intergenic 175020264 4.75 . . intergenic 175027252 6 . . intergenic 175086253 20.5 . . intergenic 175324476 5.5 . . intergenic 175368543 10 . . intergenic 175538001 6 . . intergenic 175543253 5.5 . . intergenic 175580081 5 . . intergenic 175832289 8 . . intergenic 176089775 7.5 . . intergenic 176704791 7.5 . . intergenic 176785183 3.75 . . intergenic 177398858 6 . . intergenic 177509230 3.75 ENSSSCT00000022760 EPHA3 intron 177700805 5.5 ENSSSCT00000022760 EPHA3 intron 177737286 8 ENSSSCT00000022760 EPHA3 intron 178092427 4.6 . . intergenic 178349617 5 . . intergenic 178354106 5 . . intergenic 178820394 12 . . intergenic 179313371 5 . . intergenic 180017969 7.75 . . intergenic 180029858 4.5 . . intergenic 180137892 5.75 . . intergenic 180269563 8 . . intergenic 180280602 8 . . intergenic 180320277 4.25 . . intergenic 180385468 8.5 . . intergenic 180419098 11.5 . . intergenic

0.258 0.342 0.323 0.377 . . . 0.056 . -0.077 -0.054 0.12 0.241 . -0.33 0.329 . 0.254 . . . . . 0.044 -0.07 . . . . . . . . . . . . . . . -0.103 -0.035 -0.207 . . 0.172 0.041 . . 0.003 . 0.081 . . 0.205 -0.42 . . . . 0.031 0.273 . 0.004 -0.111 0.125 -0.007 -0.05 -0.061 . 0.015 -0.047 . 0.664 0.173 . 0.1 . 0.015 0.01 0.359 -0.118 -0.102 -0.043

. . 811458 rs7916 034131 rs7863 rs791737886 . rs787955841 920706 rs7864 rs793315119 rs789213025 740885 rs7922 721935 rs7929 . rs786433717 220478 rs7866 . rs787751584 049646 rs7880 . rs790371034 787780 rs7889 rs790417242 . rs793258559 rs791588820 rs788397586 rs791981861 rs787926568 rs789840925 . . rs787891574 075525 rs7909 419068 rs7936 rs792176964 . rs791397198 rs791807898 rs787390909 rs790743569 . rs790118779 . rs790215600 . 007137 rs7915 646186 rs7872 rs792439866 920788 rs7933 . rs786853853 rs789992706 rs788374711 rs791433753 . . . rs788968407 . 128681 rs7929 . rs787988287 rs787491961 rs786965035 rs788386163 . 444121 rs7864 rs790870880 rs788167573 995078 rs7908 . rs793032312 rs793573974 rs789947326 rs788370904 . rs787412785 rs791901012 rs791300628 rs793195554 779359 rs7880 864231 rs7866 rs786902806 rs792869260

2 2 3 2 2 2 2 2 2 3 2 3 4 2 2 2 2 2 3 2 2 3 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 4 2 2 2 3 2 3 3 2 2 2 2 2 3 4 2 4 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2

AC.GT AT.AT AC.GT AAAAT.ATTTT ACC.GGT AC.GT AC.GT AT.AT AAAC.GTTT AC.GT AATG.CATT AAAT.ATTT AAAC.GTTT AC.GT AC.GT ATC.GAT AAAT.ATTT AT.AT AC.GT AAAT.ATTT AAT.ATT AT.AT AT.AT AT.AT AT.AT AT.AT AT.AT AGGG.CCCT AAC.GTT AT.AT AAC.GTT AAAAAT.ATTTTT AC.GT AAC.GTT AAAT.ATTT AAAT.ATTT AC.GT AAAC.GTTT AG.CT AC.GT AAAAAC.GTTTTT AG.CT AAAAAC.GTTTTT AAAG.CTTT AGG.CCT AAC.GTT AT.AT AT.AT AT.AT AC.GT AC.GT AAAAC.GTTTT AAAT.ATTT ACC.GGT ACT.AGT AT.AT AC.GT AAAC.GTTT AT.AT AAAT.ATTT AAAC.GTTT AAAC.GTTT AAAT.ATTT AAC.GTT AC.GT AATG.CATT AAAAG.CTTTT AAAAT.ATTTT AC.GT AC.GT AC.GT AG.CT AC.GT AAAT.ATTT AT.AT AAAT.ATTT AC.GT AC.GT AG.CT AG.CT AT.AT AT.AT AAGG.CCTT AT.AT

13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13

180663171 180903079 180908583 181204815 181707449 181832325 181922151 181942523 182363857 182600228 182777057 182811126 182849847 183036252 183036540 183077980 183105168 183218057 183368374 183799448 183821078 183838534 184222968 184283269 184290050 184353022 184482449 184506333 185268220 185465502 185653203 185682341 185722995 185819861 185917490 185939521 186006330 186064544 186232457 186316281 186452254 186637551 186638095 186643327 186715826 186767983 186804229 186957102 187005368 187063117 187120459 187130860 187194932 187517857 187518006 187630196 187868628 187956200 188092742 188185701 188408283 188455871 188677960 188690428 188691157 188695629 188718612 188787949 188803175 188908058 188952346 189021291 189265792 189305517 189376683 189529890 189710263 189750950 189758305 190000518 190389953 190429103 190497012 190503808

180663204 180903089 180908594 181204842 181707461 181832338 181922163 181942539 182363879 182600247 182777083 182811141 182849861 183036264 183036550 183078001 183105182 183218077 183368400 183799475 183821093 183838545 184222978 184283281 184290073 184353049 184482468 184506346 185268241 185465511 185653219 185682373 185723007 185819874 185917501 185939535 186006346 186064562 186232472 186316300 186452274 186637560 186638132 186643350 186715842 186768014 186804240 186957117 187005387 187063132 187120471 187130880 187194963 187517879 187518020 187630221 187868640 187956222 188092751 188185716 188408309 188455896 188677976 188690444 188691166 188695646 188718630 188787979 188803194 188908068 188952356 189021300 189265803 189305536 189376701 189529913 189710282 189750972 189758319 190000528 190389962 190429117 190497047 190503819

17 5.5 6 5.6 4.33333 7 6.5 8.5 5.75 10 6.75 4 3.75 6.5 5.5 7.33333 3.75 10.5 13.5 7 5.33333 6 5.5 6.5 12 14 10 3.5 7.33333 5 5.66667 5.5 6.5 4.66667 3 3.75 8.5 4.75 8 10 3.5 5 6.33333 6 5.66667 10.6667 6 8 10 8 6.5 4.2 8 7.66667 5 13 6.5 5.75 5 4 6.75 6.5 4.25 5.66667 5 4.5 3.8 6.2 10 5.5 5.5 5 6 5 9.5 6 10 11.5 7.5 5.5 5 7.5 9 6

. . intergenic ENSSSCT00000013130 CADM2 intron ENSSSCT00000013130 CADM2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000024901 . intron ENSSSCT00000031865 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000013132 . intron ENSSSCT00000013132 . intron ENSSSCT00000013132 . intron ENSSSCT00000013132 . intron ENSSSCT00000013132 . intron ENSSSCT00000013132 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000013136 . intron ENSSSCT00000013137 . intron ENSSSCT00000013139 SAMSN1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

0.273 -0.257 0.004 -0.242 -0.053 . . . . . 0.017 . -0.085 -0.066 -0.24 . 0.268 . . 0.834 0.032 . 0.141 0.417 0.056 . -0.084 -0.097 -0.009 -0.116 -0.059 0.054 . -0.054 0.026 -0.121 . -0.095 . 0.104 0.008 -0.102 . -0.271 0.223 0.153 -0.006 -0.12 . 0.461 0.002 0.505 0.58 . . -0.058 0.045 -0.055 0.261 0.106 0.165 -0.06 0.17 0.099 -0.023 -0.172 . 0.051 -0.127 -0.107 -0.212 -0.014 . . 0.533 0.062 0.539 0.101 0.034 0.05 0.603 0.095 -0.044 .

. rs786543319 rs788824551 rs787771507 . . rs793740087 . 826086 rs7871 . rs787425028 rs787889767 020475 rs7902 . rs791853220 rs792575305 rs787801344 rs789143462 rs787270395 rs786996946 rs788416194 rs788864876 rs790648650 rs788649801 rs793240004 rs791978160 . rs788296666 . rs791772427 626994 rs7904 rs791340111 rs787289738 . rs791274622 rs787117823 807256 rs7893 504833 rs7906 . rs786853194 rs786645395 . rs792286979 445745 rs7886 rs787835464 904951 rs7897 rs793489650 . rs787571072 405705 rs7937 . rs789856921 278228 rs7872 rs788239117 . . . 663464 rs7915 . 896992 rs7888 549785 rs7913 rs787546872 281382 rs7902 rs786901222 . 755616 rs7889 375903 rs7905 839512 rs7875 . rs789499107 rs786410731 rs788455001 rs786333872 rs793119984 . 478839 rs7880 rs792869020 357129 rs7921 058699 rs7915 rs786946961 rs790968432 . 862714 rs7900 rs787924237

2 2 2 2 2 2 3 4 2 4 2 2 4 3 5 2 2 2 2 2 2 2 2 2 2 3 3 2 2 4 2 2 4 2 2 2 2 2 4 2 2 3 2 2 2 2 3 2 2 2 4 2 2 2 2 2 4 2 2 2 2 2 2 3 4 2 2 2 4 2 2 2 2 2 2 2 3 2 2 4 2 2 2 2

AAAT.ATTT AC.GT AAC.GTT AC.GT AC.GT AAG.CTT AAAG.CTTT AAAAT.ATTTT AAC.GTT AAAC.GTTT AAC.GTT AC.GT AG.CT AAC.GTT AAT.ATT AAAC.GTTT AT.AT AAAG.CTTT AAAAC.GTTTT AC.GT AAG.CTT AAC.GTT AG.CT AT.AT AAAAC.GTTTT AC.GT AAT.ATT AAAC.GTTT AAT.ATT AT.AT AC.GT AC.GT AAAC.GTTT AATC.GATT AAT.ATT AAC.GTT AAC.GTT AC.GT AAAAAC.GTTTTT AG.CT AT.AT AAAC.GTTT AAAT.ATTT AAGGAG.CTCCT AT.AT AT.AT AAAC.GTTT AT.AT AAC.GTT AAC.GTT AG.CT AAAT.ATTT AC.GT AAAT.ATTT AC.GT AG.CT ACACC.GGTGT AAAC.GTTT AG.CT AG.CT AC.GT AC.GT AG.CT AAAT.ATTT AAAT.ATTT AAT.ATT AAT.ATT AC.GT AC.GT AC.GT AC.GT AAAC.GTTT ACATAT.ATATGT AAC.GTT AG.CT AAAT.ATTT AG.CT AC.GT AAAC.GTTT AT.AT AC.GT AG.CT AAC.GTT AAAT.ATTT

13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13

190584657 190673038 190784126 190940456 190940456 191111954 191135786 191215604 191311224 191456023 191485310 191704124 191704770 192191520 192232476 192443773 192721722 193447154 193826089 193835521 193900001 193948385 194009399 194324615 194637270 194693330 194784637 194806327 194820470 194958050 194981890 195248468 195406707 195415639 195597064 195632254 195799932 196002250 196146120 196245121 196304031 196305223 196320746 196465850 196574569 196746481 196966995 196982628 197195550 197235143 197603757 197680317 197729230 197844661 198163399 198397962 198437969 198656597 198733550 198960852 199060709 199061623 199081571 199160277 199160277 199293529 199293529 199341044 199341044 199462061 199462061 199578943 199583909 199708897 199778956 199935182 200383482 200396760 200421551 200495344 200523610 200538067 200618448 200838629

190584673 190673048 190784139 190940466 190940466 191111970 191135802 191215618 191311237 191456044 191485330 191704134 191704790 192191534 192232498 192443785 192721731 193447184 193826112 193835546 193900016 193948398 194009413 194324631 194637288 194693343 194784649 194806345 194820504 194958059 194981902 195248478 195406727 195415660 195597085 195632281 195799948 196002273 196146144 196245132 196304058 196305234 196320758 196465878 196574579 196746492 196967009 196982638 197195561 197235156 197603769 197680347 197729242 197844686 198163410 198397974 198437991 198656623 198733559 198960864 199060718 199061641 199081581 199160299 199160299 199293542 199293542 199341065 199341065 199462076 199462076 199578957 199583928 199708913 199778968 199935200 200383491 200396770 200421573 200495362 200523626 200538076 200618460 200838647

4.25 5.5 4.66667 5.5 5.5 5.66667 4.25 3 4.66667 5.5 7 5.5 10.5 5 7.66667 3.25 5 7.75 4.8 13 5.33333 4.66667 7.5 8.5 3.8 7 4.33333 4.75 11.6667 5 6.5 5.5 5.25 5.5 7.33333 9.33333 5.66667 12 4.16667 6 14 3 3.25 4.83333 5.5 6 3.75 5.5 4 4.66667 6.5 7.75 6.5 6.5 6 6.5 4.6 6.75 5 6.5 5 9.5 5.5 5.75 5.75 4.66667 4.66667 11 11 8 8 3.75 3.33333 5.66667 6.5 4.75 5 5.5 5.75 9.5 8.5 5 4.33333 4.75

. . intergenic . . intergenic . . intergenic ENSSSCT00000022689 USP25 intron ENSSSCT00000027672 USP25 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000013151 . intron ENSSSCT00000013151 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000024945 JAM2 intron ENSSSCT00000023520 JAM2 intron ENSSSCT00000013154 APP intron ENSSSCT00000013153 APP intron ENSSSCT00000013154 APP intron ENSSSCT00000013153 APP intron ENSSSCT00000013154 APP intron ENSSSCT00000013153 APP intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000013159 ADAMTS5 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

-0.077 -0.024 0.138 -0.006 -0.006 . 0.092 0.168 1.913 -0.021 0.173 0.038 . . . . 0.128 0.053 0.05 . 0.532 -0.228 -0.023 0.137 0.075 -0.094 -0.037 0.185 0.063 0.072 -0.023 -0.139 0.025 0.252 0.047 -0.111 0.091 0.14 . -0.058 . 0.063 0.089 . -0.082 -0.161 -0.034 . . . -0.312 -0.2 . . -0.105 0.097 -0.058 0.095 -0.046 . . . 0.209 . . -0.055 -0.055 0.259 0.259 . . 0.02 . 0.071 0.09 0.058 0.315 0.113 -0.095 -0.025 . -0.022 0.032 -0.18

rs791717364 rs789356326 365959 rs7927 rs790287437 rs790287437 rs793778958 rs790141548 rs789476969 rs792272271 rs787888337 rs788616681 . rs787993722 rs700207044 641077 rs7918 rs789897803 rs792425644 rs791420001 253225 rs7908 rs787890387 . rs787181926 rs791459050 rs793588797 rs791091127 732209 rs7890 rs786525791 rs791412263 rs793093181 . rs786813782 rs790762832 rs788320697 141903 rs7925 rs792666218 rs787739408 148260 rs7921 . rs789152540 . rs789851275 rs790755632 rs792436606 rs786407122 rs787038350 240159 rs7868 rs791415801 rs793398620 rs788973873 . rs786705444 rs786292750 rs793810963 . . rs789371945 208068 rs7863 rs790791967 . rs791948569 . 404104 rs7929 868658 rs7915 rs788922203 rs788922203 401061 rs7935 401061 rs7935 . . . . rs788087639 rs786708689 rs791922989 rs791652846 rs788779893 rs786883431 rs791556412 404227 rs7887 . . rs791242765 rs788010440 rs793553889

2 2 2 3 3 2 2 2 4 2 2 2 6 5 4 2 3 2 2 3 2 2 3 2 2 2 2 2 2 4 3 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 3 2 3 2 3 2 3 2 2 2 2 2 3 3 2 2 2 2 2 5 5 2 2 2 2 2 2 4 4 2 5 4 2 2 2 2

AT.AT AAAT.ATTT AT.AT AAAC.GTTT AT.AT AAAC.GTTT AT.AT AC.GT AAC.GTT AAAC.GTTT AT.AT AAAG.CTTT AAAAC.GTTTT AAAG.CTTT AC.GT AAAC.GTTT AAAT.ATTT AT.AT AAAT.ATTT AAT.ATT AAAC.GTTT AAAG.CTTT AC.GT AT.AT AAC.GTT AC.GT AAC.GTT AG.CT AG.CT AAAAAT.ATTTTT AAAAC.GTTTT AAAAG.CTTTT AAAC.GTTT AAAC.GTTT AC.GT AAC.GTT AAAC.GTTT AAAG.CTTT AAAAC.GTTTT AATG.CATT AAAAAG.CTTTTT AAG.CTT AC.GT AAAAC.GTTTT AAAAC.GTTTT AAAG.CTTT AAAC.GTTT AG.CT AAAG.CTTT AAG.CTT AATC.GATT AG.CT AC.GT AT.AT AC.GT AAAG.CTTT AAAT.ATTT AAAT.ATTT AAAG.CTTT AAAAC.GTTTT AC.GT AAC.GTT AT.AT AC.GT AAAC.GTTT AC.GT AC.GT AC.GT AAC.GTT AAAT.ATTT AAAT.ATTT AT.AT AAAG.CTTT AGG.CCT AAAAAT.ATTTTT AAAAAG.CTTTTT AT.AT AAAC.GTTT AAAT.ATTT AAT.ATT AC.GT AT.AT AG.CT AG.CT

13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13

201031400 201109699 201113579 201165716 201313985 201329519 201336149 201347467 201589868 201592872 201628048 201716303 201865237 201903525 202182805 202191391 202248909 202274814 202492783 202515507 202594350 202795869 203056723 203074622 203421784 203679867 203790256 204089632 204132804 204219076 204232873 204240795 204268035 204273839 204422172 204487881 204526320 204883713 204949871 204961716 204964003 205082796 205138695 205296172 205296172 205467442 205763565 206107102 206203995 206530178 206630483 206631644 206781403 207022997 207248334 207477130 207514368 207677284 207750034 207901674 207994317 208028379 208106886 208120666 208191402 208251515 208427282 208432676 208725599 209069656 209111459 209219948 209382692 209459003 209587413 209603207 209612569 209851008 210092848 210236980 210306230 210328189 210419903 210536423

201031409 201109731 201113603 201165727 201313998 201329537 201336160 201347488 201589887 201592888 201628065 201716327 201865256 201903539 202182814 202191406 202248936 202274828 202492800 202515520 202594368 202795885 203056732 203074633 203421799 203679882 203790277 204089646 204132825 204219096 204232888 204240817 204268061 204273873 204422182 204487900 204526336 204883725 204949889 204961738 204964032 205082813 205138706 205296187 205296187 205467464 205763593 206107120 206204013 206530203 206630500 206631653 206781417 207023006 207248346 207477161 207514381 207677300 207750050 207901700 207994328 208028395 208106896 208120677 208191422 208251524 208427296 208432692 208725614 209069682 209111482 209219969 209382721 209459021 209587445 209603229 209612581 209851026 210092878 210237003 210306243 210328198 210419935 210536441

5 8.25 12.5 3 7 4.75 6 11 6.66667 4.25 9 6.25 4 3.75 5 4 7 7.5 4.5 4.66667 4.75 4.25 5 6 5.33333 8 7.33333 7.5 11 3.5 3.2 4.6 6.75 8.75 5.5 6.66667 4.25 3.25 3.8 5.75 5 6 6 3.2 3.2 5.75 7.25 9.5 4.75 8.66667 4.5 5 7.5 5 6.5 8 3.5 4.25 4.25 5.4 6 5.66667 5.5 6 5.25 5 7.5 8.5 5.33333 6.75 6 11 7.5 6.33333 5.5 3.83333 6.5 4.75 7.75 8 7 5 16.5 9.5

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000028121 GRIK1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000031132 TIAM1 intron ENSSSCT00000013166 TIAM1 intron . . intergenic ENSSSCT00000020619 U6 promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000030581 CRYZL1 intron ENSSSCT00000027819 ITSN1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000029780 CLIC6 intron ENSSSCT00000029780 CLIC6 intron . . intergenic ENSSSCT00000013183 RUNX1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000013185 CBR3 intron ENSSSCT00000013188 CHAF1B intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000013191 HLCS intron

-0.085 . -0.154 -0.171 0.026 . 0.036 0.212 0.12 . 0.037 -0.041 -0.127 -0.009 0.2 . -0.056 0.116 . . . . -0.045 0.212 -0.173 -0.105 0.054 -0.017 0.03 -0.278 0.146 -0.043 -0.063 -0.152 -0.177 . . 0.385 -0.193 -0.01 -0.022 -0.031 -0.066 0.564 0.564 0.199 0.307 . . -0.118 -0.184 0.541 . 0.148 . 0.161 . 0.05 0.043 0.128 -0.148 0.058 -0.1 -0.422 . -0.173 -0.201 0.307 0.031 . . 1.342 0.351 . . 0.857 -0.013 0.032 . -0.131 0.102 . 0.005 .

. rs786582733 . rs787155108 . 079034 rs7900 481791 rs7881 836113 rs7902 rs792082553 rs789383768 358266 rs6929 . rs787725045 rs791460764 . 739831 rs7921 rs788091367 . 249906 rs7894 . 206142 rs7881 rs788349071 rs786428414 519799 rs7884 rs789008871 722358 rs7925 rs788447758 rs788205154 rs789338498 rs793472911 444599 rs7912 rs787802660 . 862597 rs7919 rs786996933 262280 rs7891 . rs786588080 752954 rs7932 250519 rs7900 rs786633817 rs792116373 679667 rs7864 rs788361589 rs788361589 633711 rs7869 033865 rs7878 rs791389258 rs789128252 rs786669695 . . 654738 rs7879 rs790470125 . 274108 rs7933 . rs793535537 rs791612070 166809 rs7889 . rs791968424 . rs791441099 743090 rs7868 . . rs787994677 . . rs791019842 rs788984758 . 276756 rs7880 rs788175848 . 829253 rs7907 777432 rs7927 969543 rs7924 rs786563502 rs789108495 676826 rs7874 rs793792561 rs788782271

2 2 4 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 3 4 2 3 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 6 2 2 6 4 2 6 2 4 2 2 2 3 3 2 2 2 2 2 2 2 2 2 2

AAAAAC.GTTTTT AAAT.ATTT AC.GT AAAAC.GTTTT AAAC.GTTT AAAT.ATTT AG.CT AAAAG.CTTTT AC.GT ACAG.CTGT AC.GT AAT.ATT AC.GT AC.GT AG.CT AGAT.ATCT AAC.GTT AAC.GTT AC.GT AAAAC.GTTTT AC.GT AAAT.ATTT AC.GT AC.GT AG.CT AT.AT AC.GT GGGGG.CCCCC GGGGG.CCCCC GGGGG.CCCCC GGGGG.CCCCC GGGGG.CCCCC AG.CT AC.GT AAAC.GTTT AC.GT AAC.GTT AAAC.GTTT AC.GT AAAC.GTTT ACACC.GGTGT AGC.GCT AAAAG.CTTTT AC.GT AAAT.ATTT AT.AT AAAT.ATTT AC.GT AC.GT AAAC.GTTT AAAAT.ATTTT AAAT.ATTT ACC.GGT AG.CT AG.CT AC.GT AC.GT AAAC.GTTT AG.CT AAC.GTT AT.AT AC.GT AGG.CCT AAAAT.ATTTT AAAAAC.GTTTTT AT.AT AAAAT.ATTTT AAAC.GTTT AAAAT.ATTTT AAAAAC.GTTTTT AC.GT AATC.GATT AAAG.CTTT AAAC.GTTT AT.AT ACC.GGT AAAC.GTTT AC.GT AG.CT AG.CT AC.GT AATT.AATT AAAG.CTTT AAC.GTT

13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14

210628052 210632449 210690573 210785420 211089086 211294470 211510958 211763829 211798288 211886647 212122187 212140928 212398252 212466232 212474292 212622917 213306279 213514380 213552501 213745621 213969582 214189060 214216783 214370798 214440756 214560631 214919425 214999457 214999457 214999457 214999457 214999457 215023402 215073406 215246630 215474134 215481237 215486947 216397426 216544105 216636925 216744253 217284384 218139850 491997 608566 778302 790321 1483716 1508227 1536844 1666663 2018100 2737880 2949759 3051851 3055809 3183102 3494595 3538529 3673512 3705230 3736736 3810693 3830594 3986912 3992310 4097610 4123637 4139248 4298003 4482547 4663716 4884657 5047952 5073333 5482203 5566676 5577092 5703411 6075191 6779768 6868798 7149260

210628077 210632467 210690588 210785434 211089109 211294491 211510968 211763847 211798298 211886661 212122197 212140943 212398263 212466242 212474313 212622932 213306293 213514399 213552510 213745650 213969594 214189083 214216801 214370825 214440765 214560642 214919442 214999475 214999475 214999475 214999475 214999475 215023411 215073428 215246648 215474156 215481252 215486962 216397438 216544121 216636939 216744269 217284410 218139860 492010 608582 778324 790332 1483727 1508249 1536881 1666677 2018113 2737898 2949771 3051868 3055820 3183120 3494626 3538543 3673523 3705246 3736756 3810710 3830612 3986923 3992327 4097628 4123655 4139270 4298014 4482565 4663744 4884673 5047962 5073349 5482220 5566686 5577101 5703420 6075200 6779786 6868812 7149274

4.33333 4.75 8 3 6 5.5 5.5 3.8 5.5 3.75 5.5 5.33333 6 5.5 11 4 5 6.66667 5 6 6.5 6 9.5 14 5 6 9 3.16667 3.16667 3.16667 3.16667 3.16667 5 11.5 4.75 11.5 5.33333 4 6.5 4.25 3 5.66667 5.4 5.5 3.5 8.5 5.75 6 6 5.75 7.6 3.75 4.66667 9.5 6.5 9 6 4.75 16 5 6 8.5 7 3.6 3.16667 6 3.6 4.75 3.8 3.83333 6 4.75 7.25 4.25 5.5 5.66667 4.5 5.5 5 5 5 4.75 3.75 5

ENSSSCT00000013191 ENSSSCT00000013191 . ENSSSCT00000013194 . . . . . . ENSSSCT00000023594 ENSSSCT00000023594 . . . . ENSSSCT00000029140 . . ENSSSCT00000013204 ENSSSCT00000013204 . . . . . . ENSSSCT00000034038 ENSSSCT00000034940 ENSSSCT00000034771 ENSSSCT00000013211 ENSSSCT00000035557 . ENSSSCT00000013208 . ENSSSCT00000013217 . . ENSSSCT00000025792 . ENSSSCT00000028037 . ENSSSCT00000025447 . . . . . . . . . . . . . . ENSSSCT00000010511 . . . . . . . ENSSSCT00000010516 ENSSSCT00000010516 . . . ENSSSCT00000010524 ENSSSCT00000010521 ENSSSCT00000010526 . . . . . . . ENSSSCT00000010528 ENSSSCT00000010536 . .

HLCS HLCS . . . . . . . . ERG ERG . . . . SH3BGR . . DSCAM DSCAM . . . . . . MX1 MX1 MX1 MX1 MX1 . FAM3B . RIPK4 . . PDE9A . RRP1B . . . . . . . . . . . . . . . . . . . . . . . . SPTLC1 SPTLC1 . . . SLC18A1 . . . . . . . . . GFRA2 DMTN . .

intron intron intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intron intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron promoter intergenic promoter intergenic intron intergenic intergenic intron intergenic intron intergenic promoter intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intron promoter intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic

. 0.198 0.023 0.241 0.425 -0.155 0.052 . -0.022 -0.236 0.026 -0.017 0.244 . -0.57 -0.061 -0.169 . 0.217 0.027 -0.199 -0.117 0.065 -0.135 -0.113 . -0.054 -0.288 -0.288 -0.288 -0.288 -0.288 . . . -0.429 . . . 0.221 -0.338 . . . . . . . -0.355 -0.117 -0.212 . . . . -0.415 -0.259 . 0.555 -0.097 0.148 0.029 -0.249 . 0.714 -0.207 . . . . 1.457 -0.047 -0.145 0.008 -0.119 . 0.168 0.18 . -0.06 . 0.194 0.07 .

rs791400967 rs793386197 rs793096321 . rs788773152 rs792464813 . rs789008293 rs786934131 . . rs790747085 rs791140140 rs787373127 . rs791883580 . rs787682840 . rs788468602 rs791766852 rs793643402 rs793807641 rs713152239 . 606734 rs7884 . rs791546487 rs791546487 rs791546487 rs791546487 rs791546487 356985 rs7871 125581 rs7869 rs790450637 . rs788724109 rs790000996 . rs791203542 rs788508458 rs793284669 rs787075361 rs789658886 rs792157345 rs793520912 315963 rs7867 rs786985176 516276 rs7881 289546 rs7897 rs789489002 223218 rs7884 rs792925621 860680 rs7867 849589 rs7862 . 362035 rs7930 rs792282895 . rs788624018 rs787915505 802860 rs6911 rs793085551 . rs792472184 rs789511956 384429 rs7863 rs793082015 rs786403505 866311 rs7875 rs793824270 . 002078 rs7936 457611 rs7882 rs788832415 rs791904975 965302 rs7869 rs790193301 . . . rs788835676 649361 rs7896 rs790209760

2 2 2 2 2 2 4 2 2 2 4 2 3 2 2 2 2 2 2 2 2 2 2 3 3 2 4 2 2 2 2 2 2 4 2 3 2 2 2 2 2 3 2 2 2 2 2 2 3 2 2 2 2 2 2 2 3 2 5 2 2 4 2 2 2 2 4 2 3 2 3 2 2 2 2 2 2 2 2 2 2 2 3 2

AT.AT AATG.CATT AG.CT AAC.GTT AAAAC.GTTTT AG.CT AC.GT AT.AT AAC.GTT AAT.ATT AAAC.GTTT AC.GT AGAT.ATCT AT.AT AC.GT AAATG.CATTT AT.AT AC.GT AC.GT AG.CT AC.GT AC.GT AC.GT AAAC.GTTT ATC.GAT AAAC.GTTT AAGG.CCTT ATCC.GGAT AAAAC.GTTTT AAT.ATT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AC.GT AG.CT AAAT.ATTT AAAT.ATTT AC.GT AG.CT AAAG.CTTT AC.GT AAAAC.GTTTT AGC.GCT AAAAC.GTTTT AAG.CTT AAAT.ATTT AAAC.GTTT AT.AT AT.AT AC.GT AC.GT AAAAG.CTTTT AC.GT AG.CT AC.GT AAT.ATT AAAG.CTTT AAAAT.ATTTT ATC.GAT AC.GT AAC.GTT AAGG.CCTT AAC.GTT AG.CT AG.CT AC.GT AAAAAC.GTTTTT AAAAC.GTTTT AAAC.GTTT AC.GT AAAG.CTTT AC.GT AAAT.ATTT AC.GT AAAC.GTTT AAAC.GTTT AC.GT AAAG.CTTT AAAC.GTTT AAAT.ATTT AAT.ATT AAAAT.ATTTT

14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14

7346536 7448191 7729173 8409667 8412002 8946417 8975508 9376934 9403020 9584228 9686706 9703663 9730791 9913438 10363270 10569334 10747817 10792086 10816991 10970817 11114367 11215250 11319149 11456361 11458887 11498762 11588508 11858503 11954616 12000129 12524230 12524230 12524230 12524230 12524230 12570705 12606676 12690849 12731791 12800633 13194254 13396395 13420516 13614573 13620387 13637459 13681054 13686069 13714065 14031371 14031371 14158960 14225686 14228378 14244067 14257015 14318289 14409639 14680014 14978734 15160949 15193452 15421106 15601723 15907738 15954581 15992530 16385033 16473012 16694142 17074002 17194365 17331605 17390198 17578013 17785426 17848733 17922341 17941638 18018293 18199148 18204844 18552646 18563196

7346560 7448211 7729187 8409692 8412031 8946440 8975518 9376944 9403039 9584240 9686720 9703681 9730802 9913452 10363282 10569352 10747826 10792096 10817009 10970829 11114377 11215261 11319161 11456381 11458911 11498776 11588526 11858531 11954636 12000141 12524243 12524243 12524243 12524243 12524243 12570716 12606687 12690872 12731809 12800648 13194266 13396407 13420537 13614593 13620403 13637478 13681066 13686099 13714085 14031389 14031389 14158970 14225719 14228394 14244084 14257025 14318299 14409658 14680035 14978770 15160963 15193472 15421122 15601740 15907754 15954593 15992544 16385047 16473046 16694160 17074016 17194386 17331631 17390210 17578027 17785439 17848749 17922370 17941657 18018311 18199168 18204861 18552659 18563218

12.5 5.25 7.5 8.66667 6 12 5.5 5.5 6.66667 4.33333 3.75 9.5 3 7.5 6.5 3.8 5 5.5 9.5 6.5 5.5 6 6.5 5.25 8.33333 3.75 4.75 7.25 4.2 4.33333 4.66667 4.66667 4.66667 4.66667 4.66667 6 6 6 4.75 8 6.5 3.25 11 4.2 5.66667 4 4.33333 7.75 5.25 9.5 9.5 5.5 17 3.4 9 5.5 5.5 6.66667 5.5 7.4 5 10.5 5.66667 4.5 5.66667 6.5 7.5 7.5 5.83333 3.8 3.75 11 6.75 6.5 3.75 7 4.25 7.5 10 4.75 5.25 4.5 4.66667 4.6

ENSSSCT00000010555 ENSSSCT00000010558 . . . . . . . . . . . . . ENSSSCT00000010579 . . . . ENSSSCT00000010585 . . . . ENSSSCT00000010590 . ENSSSCT00000010593 . . ENSSSCT00000010601 ENSSSCT00000036649 ENSSSCT00000035611 ENSSSCT00000033441 ENSSSCT00000034107 ENSSSCT00000025007 . ENSSSCT00000010603 ENSSSCT00000010604 . . ENSSSCT00000010612 ENSSSCT00000010612 . . . ENSSSCT00000010614 ENSSSCT00000010614 . ENSSSCT00000010617 ENSSSCT00000010616 ENSSSCT00000010618 ENSSSCT00000010618 ENSSSCT00000010618 ENSSSCT00000010618 ENSSSCT00000010618 ENSSSCT00000010618 . ENSSSCT00000010619 ENSSSCT00000010619 . . ENSSSCT00000010627 . . . . . . . ENSSSCT00000010637 . . . . . . ENSSSCT00000010641 . . . . . .

CCAR2 PEBP4 . . . . . . . . . . . . . DOCK5 . . . . . . . . . BNIP3L . ALPHA-1A . . CLU CLU CLU CLU CLU SCARA3 . ESCO2 PBK . . FBXO16 FBXO16 . . . EXTL3 EXTL3 . HMBOX1 HMBOX1 KIF13B KIF13B KIF13B KIF13B KIF13B KIF13B . MSRA MSRA . . PINX1 . . . . . . . FBXO8 . . . . . . GALNT7 . . . . . .

intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intron intergenic intron intergenic intergenic intron intron intron intron intron intron intergenic intron intron intergenic intergenic intron intron intergenic intergenic intergenic intron intron intergenic intron intron intron intron intron intron intron intron intergenic intron intron intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic

0.164 -0.023 . -0.317 . 0.071 -0.077 -0.032 -0.005 -0.077 . 0.032 0.026 . . -0.059 0.016 0.245 0.043 0.269 1.097 -0.924 0.088 . . . -0.032 0.162 0.592 0.202 0.084 0.084 0.084 0.084 0.084 . 0.109 1.388 . . -0.144 . 0.113 . 0.134 0.087 0.031 . -0.014 0.187 0.187 -0.434 0.79 -0.064 0.607 -0.12 0.134 . 0.664 0.012 -0.166 . -0.206 0.848 . -0.524 -0.067 . -0.08 . 0.074 0.23 0.569 -0.048 0.378 . . -0.212 -0.289 0.579 . . -0.111 0.609

rs786551605 rs792639896 944106 rs7888 rs793256105 rs789983743 rs791342469 . . rs792614825 rs787453619 rs790177688 . 838996 rs7931 . rs791593380 rs788392806 rs691686128 . rs789879639 rs790529710 . 984958 rs7879 259853 rs7923 rs792550318 rs788087016 rs788977131 220305 rs7915 . 624917 rs7871 . rs791657364 rs791657364 rs791657364 rs791657364 rs791657364 rs789247999 . rs787127579 rs787919085 rs789511203 rs790538808 rs788573208 rs788584938 874685 rs7906 rs786240165 . . 571316 rs7927 rs787364606 . . rs791671713 241762 rs7869 . 459424 rs7906 rs787173718 . rs787439291 rs792994866 rs786729596 rs790538630 . 303208 rs7895 151197 rs7910 rs789981557 . . rs788738459 162645 rs7873 rs793771081 rs790870194 rs786685005 254720 rs7875 rs791834067 . 855858 rs7934 328175 rs7873 832852 rs7920 760526 rs7868 rs694348998 rs792350932 rs788864451 rs793629881 rs791845355

2 2 3 2 2 4 3 2 2 2 2 2 3 3 3 2 3 4 5 4 2 2 2 2 2 2 2 2 2 2 3 3 3 3 3 4 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 3 2 2 2 3 3 2 2 2 2 2 4 2 3 2 3 2 2 2 2 2 2 2 2

AC.GT AC.GT AAAAG.CTTTT AAC.GTT AATT.AATT AAAC.GTTT AC.GT AAAC.GTTT AC.GT AAAC.GTTT AAAC.GTTT AC.GT AAAAG.CTTTT AC.GT AG.CT AT.AT AC.GT AAGG.CCTT AC.GT AT.AT AGAT.ATCT AT.AT AAAT.ATTT AAC.GTT AC.GT AC.GT AAAAAC.GTTTTT AAAG.CTTT AG.CT AC.GT AC.GT AAAAC.GTTTT AAAAC.GTTTT ACAG.CTGT AAAC.GTTT AATC.GATT AAAAT.ATTTT AC.GT AT.AT AAC.GTT AC.GT AC.GT AC.GT AT.AT AT.AT AT.AT AC.GT AGG.CCT AAAAC.GTTTT AC.GT AC.GT AC.GT AAAAAG.CTTTTT AAAC.GTTT AAAC.GTTT AAT.ATT AG.CT AAAT.ATTT AAAT.ATTT AAAAG.CTTTT AAC.GTT AAAC.GTTT AAAAAG.CTTTTT AAAC.GTTT AAAC.GTTT AATG.CATT AT.AT AAAAC.GTTTT AC.GT AAAT.ATTT AC.GT AAAG.CTTT ACAGAG.CTCTG AT.AT AC.GT AAGG.CCTT AG.CT AAAC.GTTT AC.GT AT.AT AAAAC.GTTTT AAAT.ATTT AAAC.GTTT AC.GT

14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14

18589239 18653884 18752222 18831613 18841086 19042125 19088453 19315090 19356786 19429363 19561761 19569198 19577819 19758999 19830168 20049437 20093861 20167717 20319374 20629761 20667271 20808313 20820541 20862779 20964314 21025418 21213633 21368830 21412970 21451964 21451964 21505393 21505393 21648148 21823957 21925644 21953362 22005038 22280701 22367009 22424991 22605403 22605403 22641696 22641696 22741629 22978953 23029128 23102685 23164160 23210920 23256471 23275043 23425674 23426916 23473095 23575885 23597428 23768268 23781906 23851398 23851723 24102116 24233232 24524288 24685331 25766927 25996283 26021986 26022292 26432079 26448401 26724931 26889663 26905253 27158328 27239740 27256606 27301601 27322624 27344249 27378811 27403463 27444284

18589251 18653898 18752246 18831635 18841100 19042150 19088463 19315115 19356796 19429377 19561777 19569228 19577847 19759008 19830197 20049453 20093871 20167732 20319394 20629770 20667290 20808324 20820556 20862790 20964330 21025427 21213654 21368848 21412982 21451974 21451974 21505418 21505418 21648166 21823980 21925660 21953392 22005048 22280715 22367025 22425016 22605416 22605416 22641721 22641721 22741640 22978971 23029145 23102706 23164176 23210966 23256483 23275065 23425692 23426937 23473110 23575895 23597450 23768285 23781921 23851415 23851745 24102134 24233254 24524305 24685353 25766942 25996297 26022000 26022312 26432098 26448431 26724954 26889672 26905267 27158360 27239749 27256620 27301616 27322643 27344280 27378825 27403481 27444298

6.5 7.5 5 7.66667 3.75 6.5 5.5 6.5 5.5 3.75 4.25 15.5 5.8 5 15 8.5 5.5 4 10.5 5 5 6 4 4 8.5 5 3.66667 4.75 6.5 5.5 5.5 5.2 5.2 4.75 6 4.25 6.2 5.5 7.5 5.66667 13 7 7 13 13 6 9.5 6 4.4 8.5 23.5 6.5 3.83333 4.75 5.5 5.33333 5.5 5.75 4.5 3.2 6 5.75 3.16667 5.75 4.5 5.75 8 3 7.5 5.25 10 7.75 4 5 7.5 8.25 5 3.75 8 10 6.4 3.75 4.75 7.5

. . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000010649 ENSSSCT00000027721 ENSSSCT00000010651 ENSSSCT00000010650 ENSSSCT00000010651 ENSSSCT00000010650 . ENSSSCT00000010652 ENSSSCT00000010653 . ENSSSCT00000022985 . ENSSSCT00000010657 . ENSSSCT00000028371 ENSSSCT00000028014 ENSSSCT00000028371 ENSSSCT00000028014 . . . ENSSSCT00000010659 ENSSSCT00000010659 ENSSSCT00000010659 ENSSSCT00000010659 ENSSSCT00000010659 ENSSSCT00000010659 ENSSSCT00000010659 ENSSSCT00000010659 . . . . . . ENSSSCT00000010671 . . ENSSSCT00000010677 ENSSSCT00000010684 . . . . . . . . . . . . . . . . .

. . . . . . . . . . . . . . . . . . . . . . . . . . . CLCN3 . NEK1 NEK1 NEK1 NEK1 . SH3RF1 CBR4 . PALLD . DDX60 . ANXA10 ANXA10 ANXA10 ANXA10 . . . SPOCK3 SPOCK3 SPOCK3 SPOCK3 SPOCK3 SPOCK3 SPOCK3 SPOCK3 . . . . . . . . . GALNT9 GPR133 . . . . . . . . . . . . . . . . .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron promoter intron intron intron intron intergenic intron intron intergenic intron intergenic promoter intergenic intron intron intron intron intergenic intergenic intergenic intron intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

-0.011 0.033 . -0.234 -0.061 -0.135 0.215 -0.226 . 0.034 . . . . -0.136 -0.041 -0.268 . . -0.222 . . 0.16 . 0.013 . 0.06 0.267 0.175 . . 0.117 0.117 . . . . 0.195 0.228 0.068 0.196 0.133 0.133 -0.003 -0.003 0.086 . 0.06 . -0.024 . -0.033 -0.133 . . . . -0.194 . . . . . . . . -0.529 -0.094 . . -0.538 -0.047 . -0.49 . -0.205 -0.32 -0.307 . . -0.193 . -0.306 -0.328

621859 rs7864 rs790245846 362392 rs7059 rs699130384 . rs693177946 rs692694970 . rs793080581 rs789048652 rs793238902 949804 rs7918 rs700674711 . rs789885277 rs787800268 rs790093673 rs787530512 rs787198196 . . rs793849147 rs788371100 rs792883743 . rs695436509 799153 rs7898 297380 rs7916 . rs793443492 rs793443492 rs787036419 rs787036419 rs788813491 rs792986608 rs792754673 823792 rs7903 rs791130042 . 142492 rs7879 . rs788678528 rs788678528 rs791995613 rs791995613 rs790354788 rs709886859 491036 rs7926 275413 rs7875 . rs793855535 . rs789014607 rs791960229 111232 rs7885 rs788100199 rs792998908 070692 rs7893 rs791902483 948428 rs7879 rs786991550 071263 rs7916 rs705486960 rs789414433 rs791166863 rs790960525 . rs790555062 673898 rs7904 rs788040466 rs792377483 rs786237452 rs786415066 rs788859356 629658 rs7882 rs786768159 . 982196 rs7918 776856 rs7928 045473 rs7927 rs788653703 rs789132968 rs787427900 649421 rs7899

2 2 2 3 2 2 2 2 2 2 2 4 2 2 3 2 2 2 2 4 2 2 2 2 2 4 2 2 3 3 3 2 2 2 2 2 2 3 2 4 2 2 2 2 2 2 3 3 3 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 4 2 2 3 2 2 2 2 2 2 2

AC.GT AT.AT AG.CT AAAT.ATTT AG.CT AAAAAC.GTTTTT AAAAC.GTTTT AAAC.GTTT AAT.ATT AATC.GATT AAG.CTT AAAC.GTTT AC.GT AAG.CTT AAG.CTT AAC.GTT AC.GT AG.CT AAAC.GTTT AAAAC.GTTTT AT.AT AT.AT AAAC.GTTT AC.GT AAAAG.CTTTT AC.GT AAAC.GTTT ACACC.GGTGT AT.AT AAAAT.ATTTT AAAAT.ATTTT AATC.GATT AAAT.ATTT AG.CT AAG.CTT AAAC.GTTT AAAC.GTTT AAC.GTT AAC.GTT AAAAC.GTTTT AGG.CCT AC.GT AC.GT AC.GT AT.AT AAT.ATT AAAT.ATTT AAAT.ATTT AAAC.GTTT AAAT.ATTT AT.AT ACACGC.GCGTG AC.GT AAAC.GTTT AC.GT AC.GT AG.CT AAC.GTT AAC.GTT AAAC.GTTT AAAC.GTTT AT.AT AAGG.CCTT AAGG.CCTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AG.CT AAAAAT.ATTTTT AAG.CTT AAAAC.GTTTT AC.GT AG.CT AAAC.GTTT AAC.GTT AAAC.GTTT AAAAAC.GTTTTT AAAAC.GTTTT AAAT.ATTT AAC.GTT AG.CT ACACAT.ATGTGT AC.GT

14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14

27794635 27985563 28111956 28259852 28342004 28362320 28437992 28449894 28473061 28578047 28673450 28689932 28731121 28825250 28889873 28963522 29027868 29110487 29212623 29385614 29485409 29492382 29547350 29713365 29792190 29834340 30072056 30624973 30895586 31046795 31046795 31094434 31472204 31497228 31531640 31578479 31578479 31767757 32459654 32469770 32529921 32530718 32728680 32977113 33103827 33275436 33463361 33514604 33832291 33885094 33955323 34054889 34086389 34095289 34115278 34319820 35014844 35034973 35047205 35090480 35090480 35184594 35316114 35432144 35472678 35606563 35636920 35846325 36035650 36067667 36137721 36162962 36253606 36416628 36468295 36675923 36801165 36880274 36884560 37041926 37049149 37207730 37300488 37365171

27794649 27985573 28111972 28259876 28342016 28362343 28438020 28449912 28473077 28578066 28673466 28689947 28731152 28825275 28889906 28963543 29027878 29110503 29212639 29385637 29485418 29492401 29547372 29713384 29792213 29834349 30072074 30624987 30895596 31046810 31046810 31094457 31472226 31497240 31531656 31578493 31578493 31767771 32459670 32469790 32529937 32530742 32728694 32977147 33103849 33275451 33463387 33514637 33832312 33885109 33955336 34054922 34086405 34095312 34115290 34319834 35014854 35034992 35047226 35090502 35090502 35184604 35316135 35432166 35472697 35606586 35636951 35846339 36035659 36067689 36137742 36162990 36253616 36416645 36468314 36675947 36801183 36880291 36884583 37041942 37049164 37207746 37300508 37365183

7.5 5.5 8.5 6.25 6.5 4 5.8 4.75 5.66667 5 5.66667 4 16 8.66667 11.3333 7.33333 5.5 8.5 4.25 4.8 5 10 5.75 10 4.8 5 4.75 3 5.5 3.2 3.2 6 5.75 6.5 5.66667 3.75 3.75 5 5.66667 4.2 5.66667 12.5 7.5 17.5 11.5 5.33333 6.75 8.5 5.5 4 7 5.66667 8.5 6 6.5 7.5 5.5 6.66667 7.33333 5.75 5.75 5.5 5.5 5.75 5 6 8 3.75 5 3.83333 7.33333 5.8 5.5 9 5 8.33333 4.75 3 4.8 4.25 5.33333 8.5 3.5 6.5

ENSSSCT00000031300 SLC15A4 intron ENSSSCT00000010692 . intron ENSSSCT00000010692 . intron ENSSSCT00000010692 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000010693 TMEM132B intron ENSSSCT00000010693 TMEM132B intron ENSSSCT00000010693 TMEM132B intron . . intergenic . . intergenic ENSSSCT00000010695 AACS intron ENSSSCT00000010699 SCARB1 intron . . intergenic ENSSSCT00000010707 DNAH10 intron ENSSSCT00000010711 GTF2H3 intron ENSSSCT00000010712 EIF2B1 promoter ENSSSCT00000010714 TMED2 promoter ENSSSCT00000010723 PITPNM2 intron ENSSSCT00000010723 PITPNM2 intron ENSSSCT00000010723 PITPNM2 intron ENSSSCT00000010725 OGFOD2 3'utr ENSSSCT00000010724 ARL6IP4 promoter ENSSSCT00000010730 DENR intron . . intergenic . . intergenic ENSSSCT00000010744 WDR66 intron ENSSSCT00000010744 WDR66 intron ENSSSCT00000010751 TMEM120B intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000010768 PPTC7 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000010773 CCDC63 intron ENSSSCT00000010773 CCDC63 intron ENSSSCT00000010773 CCDC63 intron . . intergenic . . intergenic ENSSSCT00000010783 . intron ENSSSCT00000010783 . intron ENSSSCT00000032561 . intron ENSSSCT00000010783 . intron . . intergenic ENSSSCT00000010786 CCDC60 intron . . intergenic . . intergenic ENSSSCT00000010791 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000010795 SUDS3 intron ENSSSCT00000010796 TAOK3 intron . . intergenic ENSSSCT00000010801 RFC5 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000010802 KSR2 promoter ENSSSCT00000010802 KSR2 intron ENSSSCT00000010802 KSR2 intron . . intergenic

-0.284 . -0.058 -0.347 -0.344 . . -0.128 0.188 . -0.172 -0.259 -0.212 -0.243 -0.245 -0.348 -0.01 . -0.273 -0.262 . . -0.263 . 0.063 -0.873 -0.318 -0.051 1.273 0.024 0.024 0.26 -0.19 -0.374 -0.15 0.761 0.761 0.783 . 1.984 -0.342 -0.047 . -0.321 . -0.13 . -0.134 0.464 . -0.15 -0.028 0.318 -0.156 -0.229 -0.129 0.049 0.046 0.259 . . -0.021 . -0.083 -0.059 0.019 -0.18 . -0.372 0.031 0.224 . 0.042 -0.16 0.252 0.135 3.75 . 0.075 . . 0.14 -0.131 0.098

rs792549984 rs786416081 . rs792344317 rs790440171 rs788236202 rs789802100 rs790890270 309163 rs7920 rs786228866 701323 rs7900 rs786903841 rs790154934 224344 rs7919 rs790224340 rs793055253 rs793271609 rs793088220 rs792247471 041514 rs7925 rs793380917 351348 rs7933 . rs789449130 rs789507887 rs791104563 rs787983158 rs793553618 rs791367805 . . rs790856767 597962 rs7899 . 974442 rs7935 206850 rs7891 206850 rs7891 rs788325933 rs788828337 rs789658381 rs791556020 rs792585074 rs788492582 176531 rs7934 rs793436139 279469 rs7910 . rs786723958 rs790637939 rs790167385 rs787154267 305490 rs7888 rs787190365 rs786319378 650690 rs7887 rs791342430 507804 rs7915 rs787110337 rs787303554 295117 rs7913 295117 rs7913 . . rs787131861 810811 rs7879 rs787153454 rs786665708 305515 rs7884 740847 rs7929 048625 rs7934 731484 rs7896 rs786410909 . rs789423461 924293 rs7868 . 787379 rs7937 rs789551600 316121 rs7893 rs786544802 . rs786724561 692364 rs7938 .

2 2 2 2 2 2 3 2 2 2 2 2 5 4 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 4 4 2 2 2 3 2 2 2 2 5 2 2 2 3 3 2 2 2 4 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 3

AC.GT AC.GT AAAC.GTTT AAT.ATT AAAG.CTTT AAAT.ATTT AATG.CATT AC.GT ATC.GAT AC.GT AC.GT AC.GT AAAAC.GTTTT AAG.CTT AT.AT ACC.GGT AAAC.GTTT AGC.GCT AC.GT AAC.GTT AAAG.CTTT AG.CT AC.GT AG.CT AAAG.CTTT AAAT.ATTT AAAT.ATTT AATT.AATT AATG.CATT AC.GT AC.GT AAAAAG.CTTTTT AAG.CTT AAG.CTT AG.CT AAAAC.GTTTT AATG.CATT AAAC.GTTT ACAT.ATGT AAAC.GTTT AAG.CTT AC.GT AAAT.ATTT AAAAC.GTTTT AGG.CCT ACATAT.ATATGT AAAAT.ATTTT AAAAT.ATTTT AG.CT AAT.ATT AT.AT AGATG.CATCT AG.CT AGGG.CCCT AG.CT ACAG.CTGT AG.CT AAAAC.GTTTT AAAT.ATTT AG.CT AAAG.CTTT AC.GT AC.GT AC.GT AAG.CTT AAC.GTT AT.AT AAAAC.GTTTT AAAAG.CTTTT AC.GT AAC.GTT AG.CT AT.AT AG.CT AAC.GTT AG.CT AAAT.ATTT AAAC.GTTT AAAAT.ATTTT AAAC.GTTT AC.GT AAT.ATT AAAAC.GTTTT AG.CT

14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14

37708265 37796511 37865409 37899157 38104877 38190417 38226107 38835985 38990094 39128627 39160406 39560869 39887268 39942876 40190075 40204379 40406374 40428174 40624618 40758863 41140437 41178119 41197041 41396191 41740851 41802040 42047711 42246914 42293366 42714187 42714187 42859192 43256748 43256748 43907937 43915620 44190440 44274738 44437688 44445092 44469823 44529382 44619629 44825679 45178781 45559715 45580927 45580927 45711196 46087367 46120815 46291799 46672192 46730717 46878423 47089193 47186504 47190251 47242402 47388628 47587267 47754732 48195004 48470305 48797958 48906003 48916516 49155954 49224464 49252594 49279601 49659653 50047974 50049213 50107447 51166637 51300782 51733380 52149971 52263311 53392097 53997385 54660068 55466834

37708283 37796534 37865427 37899173 38104899 38190429 38226140 38835996 38990118 39128643 39160417 39560879 39887296 39942911 40190086 40204397 40406393 40428186 40624627 40758875 41140459 41178138 41197053 41396202 41740875 41802062 42047724 42246928 42293396 42714202 42714202 42859214 43256767 43256767 43907948 43915643 44190461 44274757 44437710 44445111 44469837 44529397 44619646 44825698 45178801 45559733 45580948 45580948 45711206 46087378 46120827 46291828 46672207 46730731 46878432 47089219 47186519 47190270 47242419 47388642 47587281 47754746 48195015 48470323 48797976 48906019 48916526 49155976 49224481 49252608 49279617 49659662 50047994 50049228 50107460 51166648 51300799 51733403 52149987 52263335 53392119 53997401 54660091 55466843

9.5 12 4.75 5.66667 5.75 3.25 8.5 6 8.33333 8.5 6 5.5 5.8 12 6 6.33333 5 4.33333 5 4.33333 5.75 10 6.5 6 6.25 5.75 3.5 3.75 7.75 8 8 3.83333 6.66667 6.66667 6 4.8 5.5 5 5.75 5 5 8 4.5 4 7 3.16667 4.4 4.4 5.5 4 6.5 6 8 3.75 5 6.75 8 4 4.5 7.5 3.75 7.5 6 9.5 6.33333 5.66667 5.5 4.6 3.6 7.5 5.66667 5 10.5 8 4.66667 6 4.5 6 3.4 6.25 11.5 5.66667 4.8 5

ENSSSCT00000010808 ENSSSCT00000010808 ENSSSCT00000010810 ENSSSCT00000010810 . . . . . . . . . . . . . . ENSSSCT00000010816 . ENSSSCT00000010826 ENSSSCT00000028773 ENSSSCT00000010831 . ENSSSCT00000030697 . ENSSSCT00000036207 ENSSSCT00000010843 ENSSSCT00000010843 ENSSSCT00000010848 ENSSSCT00000031208 . ENSSSCT00000010867 ENSSSCT00000010868 ENSSSCT00000010885 ENSSSCT00000010885 ENSSSCT00000010889 . ENSSSCT00000010893 ENSSSCT00000010893 . ENSSSCT00000010895 . . ENSSSCT00000025264 . ENSSSCT00000010902 ENSSSCT00000010901 . . . ENSSSCT00000010912 . . ENSSSCT00000010913 . . . . . . . . ENSSSCT00000010924 . . . . ENSSSCT00000010928 ENSSSCT00000010928 ENSSSCT00000010928 ENSSSCT00000010945 ENSSSCT00000010951 ENSSSCT00000010951 . . ENSSSCT00000010986 ENSSSCT00000010991 . . . ENSSSCT00000011056 . .

FBXW8 intron FBXW8 promoter RNFT2 intron RNFT2 intron . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic RBM19 intron . intergenic IQCD promoter . intron OAS2 intron . intergenic PTPN11 intron . intergenic TRAFD1 intron TMEM116 intron TMEM116 3'utr GCN1L1 3'utr PLA2G1B intron . intergenic SPPL3 intron SPPL3 intron UBE3B intron UBE3B intron ACACB intron . intergenic SVOP intron SVOP intron . intergenic SSH1 intron . intergenic . intergenic . cds . intergenic PIWIL3 intron PIWIL3 intron . intergenic . intergenic . intergenic MYO18B promoter . intergenic . intergenic SEZ6L intron . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic TTC28 intron . intergenic . intergenic . intergenic . intergenic KREMEN1 intron KREMEN1 intron KREMEN1 intron NIPSNAP1 intron MTMR3 intron MTMR3 intron . intergenic . intergenic DRG1 intron DEPDC5 intron . intergenic . intergenic . intergenic CRKL intron . intergenic . intergenic

. . 0.657 . 0.178 0.036 0.152 -0.126 -0.036 -0.135 -0.112 -1.032 -0.182 . . -0.386 0.07 -0.206 0.223 . . -0.05 0.011 -0.162 . 0.233 . . 0.347 1.687 1.687 . 0.342 0.342 -0.162 -0.292 -0.214 0.033 . -0.137 0.21 -0.261 0.278 0.38 1.204 . 0.252 0.252 0.193 0.017 0.299 0.389 -0.116 -0.106 0.838 -0.401 0.058 -0.432 -0.35 . -0.17 -0.041 . . . -0.046 . . 0.918 0.157 3.551 0.961 . 0.134 0.327 0.368 . . 0.116 -0.344 . 0.196 0.254 -0.295

rs789012904 rs787879530 rs792049674 rs792810188 rs704686469 . 448110 rs7914 351490 rs7925 rs791452340 rs793269571 rs789341322 080831 rs7891 rs790707045 rs790947642 143107 rs7928 339528 rs7872 932376 rs7936 . 553828 rs7893 399829 rs7914 rs792780690 rs702371938 . . rs787756673 rs706831724 rs793007621 rs787524876 rs786443693 rs787251512 rs787251512 rs787301223 853217 rs7874 853217 rs7874 . rs792842594 005232 rs7868 rs786309900 661055 rs7877 rs793124446 rs788106308 143326 rs7883 rs786693161 172457 rs7894 . 079489 rs7888 585741 rs7911 585741 rs7911 rs792999089 rs791493530 rs793335668 rs788284879 . rs792914076 . 744720 rs7916 rs790713086 848211 rs7868 493714 rs7916 909771 rs7877 rs793127006 232411 rs7937 080170 rs7893 . rs786797027 rs791950653 . rs793796845 362256 rs7935 . rs791359179 . . . . . rs791167560 200311 rs7923 307926 rs7868 809737 rs7924 rs790645052 rs792322926 709429 rs7913 .

2 4 2 2 3 2 2 2 2 2 2 2 2 2 2 3 3 2 2 2 2 2 2 2 2 2 2 2 2 4 4 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2

AAAAC.GTTTT AAAG.CTTT AT.AT AAAT.ATTT AAC.GTT AAC.GTT AAAC.GTTT AT.AT AC.GT AT.AT AAG.CTT AAAC.GTTT AAAC.GTTT AATG.CATT AT.AT AAC.GTT AT.AT AAAAT.ATTTT AC.GT AC.GT AT.AT AAAAT.ATTTT AG.CT AG.CT AAAC.GTTT AG.CT ATCC.GGAT AAAAG.CTTTT AAAG.CTTT AAAG.CTTT AAAC.GTTT AAAC.GTTT AAAT.ATTT AAAC.GTTT AC.GT AT.AT AAG.CTT AAAC.GTTT AC.GT AAAT.ATTT AT.AT AAAG.CTTT AAAAG.CTTTT AG.CT AT.AT AC.GT AAAT.ATTT AAAAG.CTTTT ACCT.AGGT AT.AT AT.AT AG.CT AAC.GTT AC.GT AC.GT AC.GT AAAATT.AATTTT AATT.AATT AAAC.GTTT AAAT.ATTT AC.GT AC.GT AAAAC.GTTTT AC.GT AAAAC.GTTTT AC.GT ATC.GAT AAAG.CTTT AAAAAC.GTTTTT AT.AT AAAC.GTTT AAAC.GTTT AGAT.ATCT AAG.CTT AAAT.ATTT AAC.GTT AAAAAC.GTTTTT AAAT.ATTT ATC.GAT AG.CT AAAAT.ATTTT AC.GT ATCC.GGAT ATCC.GGAT

14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14

55561108 55617123 55629490 55895676 55949181 55951230 56118621 56261061 56382889 56461715 56463037 56604111 57373211 57479662 57607025 57736288 57785478 57793380 57806744 58004232 58324508 58382575 58587129 58598233 58629044 58911423 58936981 59080753 59264227 59264227 59280607 59280607 59292865 59526486 59661432 59696807 59808750 59845277 60014694 60093206 60642261 60698437 60796641 60818495 60886581 60886985 60922251 60967650 61088156 61107249 61400723 61585177 61607126 61858659 61858659 62053365 62297429 62299697 63624089 63908512 64356815 64514633 64702165 64912818 65140502 65552838 65565541 65653747 65818104 66111694 66118693 66217529 66240465 66405489 67031394 67463260 67465040 67497612 67502697 67702152 67746438 68353956 68565028 68565028

55561129 55617141 55629499 55895691 55949197 55951246 56118637 56261072 56382898 56461732 56463050 56604127 57373222 57479681 57607037 57736304 57785489 57793403 57806758 58004242 58324518 58382595 58587147 58598243 58629058 58911443 58937003 59080769 59264249 59264249 59280618 59280618 59292883 59526502 59661446 59696817 59808763 59845306 60014711 60093224 60642297 60698453 60796663 60818507 60886602 60886997 60922273 60967674 61088186 61107259 61400734 61585193 61607139 61858682 61858682 62053375 62297459 62299709 63624112 63908533 64356828 64514656 64702185 64912832 65140530 65552850 65565559 65653761 65818129 66111718 66118717 66217548 66240484 66405512 67031411 67463275 67465065 67497623 67502712 67702163 67746465 68353968 68565055 68565055

4.4 4.75 5 4 5.66667 5.66667 4.25 6 5 9 4.66667 4.25 3 5 6.5 5.66667 6 4.8 7.5 5.5 5.5 4.2 9.5 5.5 3.75 10.5 5.75 3.4 5.75 5.75 3 3 4.75 4.25 7.5 5.5 4.66667 7.5 9 4.75 18.5 4.25 4.6 6.5 11 6.5 5.75 5 7.75 5.5 6 8.5 4.66667 12 12 5.5 5.16667 3.25 6 5.5 7 12 4.2 7.5 5.8 6.5 6.33333 3.75 4.33333 12.5 6.25 5 5 8 4.5 5.33333 4.33333 3 5.33333 6 5.6 6.5 7 7

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011103 RYR2 intron ENSSSCT00000011103 RYR2 intron ENSSSCT00000011103 RYR2 intron ENSSSCT00000011103 RYR2 intron ENSSSCT00000011103 RYR2 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000011105 MTR intron ENSSSCT00000011105 MTR intron . . intergenic ENSSSCT00000030665 EDARADD intron ENSSSCT00000030665 EDARADD intron ENSSSCT00000011111 ERO1LB promoter ENSSSCT00000011112 . intron ENSSSCT00000011114 . intron ENSSSCT00000011112 . intron ENSSSCT00000011114 . intron ENSSSCT00000011112 . intron . . intergenic ENSSSCT00000011115 LYST intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011120 ARID4B intron . . intergenic . . intergenic ENSSSCT00000011124 TARBP1 intron . . intergenic ENSSSCT00000011127 SLC35F3 intron ENSSSCT00000011127 SLC35F3 intron ENSSSCT00000011127 SLC35F3 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011130 . intron ENSSSCT00000026272 PCNXL2 intron ENSSSCT00000011131 PCNXL2 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011142 C1orf131 intron ENSSSCT00000011149 COG2 intron . . intergenic . . intergenic ENSSSCT00000011151 GALNT2 intron ENSSSCT00000011154 ABCB10 intron . . intergenic . . intergenic ENSSSCT00000023762 ZNF33B intron ENSSSCT00000011162 . intron . . intergenic . . intergenic ENSSSCT00000011166 SGALNACT intron ENSSSCT00000011166 SGALNACT intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011175 FAM13C intron . . intergenic . . intergenic . . intergenic ENSSSCT00000035859 ANK3 intron ENSSSCT00000033954 ANK3 intron

-0.019 -0.397 0.003 -0.365 -0.158 -0.122 0.026 -0.145 -0.167 -0.068 -0.092 0.029 . -0.074 . -0.233 -0.174 -0.208 -0.398 -0.167 . 0.133 0.347 -0.104 0.289 0.145 0.004 0.008 . . . . -0.134 0.093 0.169 -0.097 . -0.007 . 1.154 . 0.32 0.188 0.267 . -0.011 -0.136 -0.073 0.046 -0.257 0.15 . -0.144 . . 0.054 -0.033 -0.02 . -0.12 -0.132 0.12 . -0.189 . 0.116 . . . 0.093 0.167 0.284 0.17 . 0.011 . 0.124 0.952 0.186 -0.13 . . 1.869 1.869

334216 rs7927 003832 rs7924 rs786774931 011153 rs7889 . rs793024995 rs787524929 . rs790903453 rs792627774 rs789512375 rs786657623 . rs786286746 963039 rs7937 rs787859271 rs790185061 731952 rs7930 . rs792604062 rs787725610 rs792053458 rs787918567 rs792269431 625766 rs7878 rs788693512 517874 rs7915 512501 rs7912 786373 rs7862 786373 rs7862 rs789456907 rs789456907 rs789541292 rs792408674 582102 rs7932 rs786306465 845200 rs7897 292281 rs7909 . rs787868089 rs792712968 rs789424707 959279 rs7913 . rs792321760 rs789536151 rs786274974 rs789105536 799633 rs7897 rs786726686 rs787819139 . rs789533263 rs790514914 rs790514914 . . rs791026695 rs792424976 222599 rs7896 147338 rs7913 929451 rs7895 rs789287231 rs789489793 rs787373638 rs791210534 . rs789057917 828826 rs7872 195140 rs7883 075810 rs7877 964553 rs7874 382214 rs7899 rs788739417 . rs787408063 . 245449 rs7878 658724 rs7871 rs787404107 rs787011245 203044 rs7867 rs793886336 rs793886336

2 2 2 2 2 2 2 2 3 2 2 2 2 2 4 2 2 2 4 2 2 2 2 2 2 2 2 2 3 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 3 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 4 2 2 2 2 2 2 2 3 2 2

ATCC.GGAT ATCC.GGAT AC.GT AC.GT AC.GT AC.GT AAGG.CCTT AAC.GTT AAAAC.GTTTT AAAT.ATTT AC.GT AAC.GTT AC.GT AAAAC.GTTTT AAAT.ATTT AAAAT.ATTTT AT.AT AAAT.ATTT AG.CT AC.GT AC.GT AAG.CTT AAAC.GTTT AT.AT AT.AT AATG.CATT AAAAC.GTTTT AT.AT AC.GT AAAT.ATTT AC.GT AAAT.ATTT AAAAAC.GTTTTT AAAAAC.GTTTTT AAAC.GTTT AAAC.GTTT AC.GT AG.CT AT.AT AC.GT AAT.ATT AC.GT AC.GT AATAT.ATATT AAC.GTT AAAAC.GTTTT AAAC.GTTT AT.AT ACCT.AGGT AAC.GTT AAAT.ATTT AAAT.ATTT AAAC.GTTT AT.AT AT.AT ACATAT.ATATGT AC.GT AC.GT AAAAC.GTTTT AAAAC.GTTTT AG.CT AAAT.ATTT AAAC.GTTT AAAC.GTTT AAAT.ATTT AG.CT AAAAG.CTTTT AT.AT AT.AT AAAACC.GGTTTT AAC.GTT AAT.ATT AAAT.ATTT AAAAC.GTTTT AC.GT AAAAT.ATTTT AAAAG.CTTTT AAATG.CATTT AT.AT AC.GT AT.AT AC.GT AC.GT AC.GT

14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14

68565028 68565028 68576094 68576094 68576094 68576094 68842892 68922243 68991509 69033177 69034895 69050442 69090986 69537438 69679552 69814080 69852533 69933898 70234861 70253450 70407149 70573041 70720505 70930847 70938686 71284906 71326612 71651129 71659411 71743493 71828414 71896763 71973501 72022208 72143776 72328157 72377526 72589187 72623243 72627660 72901475 72935348 72954610 73028434 73144093 73191458 73354317 73472766 73511764 73545303 73644145 73659194 73669069 73814234 74224832 74301281 74988612 75387469 75581200 75634451 75763495 75833610 75977367 76016891 76034957 76048170 76280556 76388256 76418829 76830991 77057385 78398506 78404085 78434191 78864023 79005244 79032162 79034210 79398856 79712021 79793432 79811844 79840980 79915906

68565055 68565055 68576115 68576115 68576115 68576115 68842918 68922260 68991529 69033194 69034919 69050455 69090996 69537466 69679569 69814098 69852543 69933918 70234871 70253462 70407161 70573057 70720525 70930864 70938696 71284934 71326645 71651138 71659421 71743514 71828423 71896787 71973531 72022231 72143804 72328180 72377540 72589210 72623252 72627672 72901493 72935358 72954623 73028449 73144105 73191500 73354334 73472792 73511783 73545323 73644165 73659212 73669081 73814244 74224842 74301307 74988622 75387502 75581218 75634469 75763508 75833632 75977393 76016905 76034976 76048181 76280572 76388265 76418839 76831011 77057396 78398521 78404103 78434211 78864033 79005264 79032181 79034227 79398867 79712037 79793443 79811859 79841002 79915917

7 7 11 11 11 11 6.75 6 4.2 4.5 12.5 4.66667 5.5 5.8 4.5 3.8 5.5 5.25 5.5 6.5 6.5 5.66667 5.25 9 5.5 7.25 6.8 5 5.5 5.5 5 6.25 5.16667 4 7.25 6 7.5 12 5 6.5 6.33333 5.5 7 3.2 4.33333 8.6 4.5 13.5 5 7 5.25 4.75 3.25 5.5 5.5 4.5 5.5 17 3.8 3.8 7 5.75 6.75 3.75 5 6 3.4 5 5.5 3.5 4 5.33333 4.75 4.2 5.5 4.2 4 3.6 6 8.5 6 8 11.5 6

ENSSSCT00000011178 ANK3 intron ENSSSCT00000034950 ANK3 intron ENSSSCT00000035859 ANK3 intron ENSSSCT00000033954 ANK3 intron ENSSSCT00000011178 ANK3 intron ENSSSCT00000034950 ANK3 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011188 ZNF365 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011192 JMJD1C intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011202 SIRT1 intron ENSSSCT00000024082 . promoter ENSSSCT00000024082 . intron ENSSSCT00000024082 . intron ENSSSCT00000011226 COL13A1 intron ENSSSCT00000011229 TYSND1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

1.869 1.869 -0.097 -0.097 -0.097 -0.097 0.014 0.123 0.205 -0.066 . 0.244 . -0.017 -0.09 0.098 0.489 -0.104 . 0.141 . -0.134 . . 0.288 0.04 0.11 . -0.11 . 0.273 3.567 0.152 . . 0.054 0.355 0.344 . 0.128 -0.18 0.02 . . . . 0.045 . 0.423 0.018 0.06 . . 0.15 . -0.063 . 0.276 0.174 0.051 0.391 -0.045 0.006 0.105 -0.209 -0.123 0.227 0.282 . 0.167 0.154 -0.157 -0.096 -0.206 -0.035 -0.131 0.175 . . -0.111 -0.113 -0.164 . -0.157

rs793886336 rs793886336 . . . . 305094 rs7886 rs792992330 rs790618478 rs786709721 206841 rs7910 rs787770105 . rs786340202 012970 rs7938 720916 rs7902 rs791015605 . rs789031676 rs792916873 965633 rs7934 240374 rs7933 644143 rs7866 rs790855693 rs787896863 rs788248513 941555 rs7895 . rs792978989 rs790387962 rs790775511 062750 rs7938 003473 rs7862 . rs790150268 rs788443623 289795 rs7936 rs791874533 rs786352749 rs788346881 . rs787738198 rs788446582 658431 rs7893 . 181302 rs7862 rs790456899 247343 rs7913 rs789465383 884399 rs7915 . rs792268086 878525 rs7928 rs790273431 rs789960881 rs791649817 . . rs788113688 rs791234685 . 153304 rs7873 960376 rs7915 rs791761972 rs786710025 rs792597052 rs790739385 rs791383088 . rs792699909 rs791570588 rs786501554 rs791726745 rs787640133 rs791780673 rs790493403 446658 rs7901 rs793203243 rs787087365 570206 rs7920 rs791656049 489485 rs7893 rs791496715 rs789999213

2 2 4 4 4 4 2 2 2 3 3 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 3 3 2 2 4 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 3 2 2 3 2 2 2 2 3 2 2 2 2 2 3 2 2 3 4

AAAT.ATTT AC.GT AC.GT AAAC.GTTT AAT.ATT AAAAT.ATTTT AAAAT.ATTTT AC.GT AT.AT AT.AT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AG.CT AG.CT AC.GT AC.GT AAC.GTT AAAAT.ATTTT AAAG.CTTT AT.AT AG.CT AG.CT AAT.ATT AAAT.ATTT AAAC.GTTT AAAT.ATTT AG.CT AC.GT AC.GT ACCCC.GGGGT AG.CT AAC.GTT AAC.GTT AT.AT AAAAC.GTTTT AC.GT AATC.GATT AG.CT ACAT.ATGT AATG.CATT AAAT.ATTT AAAT.ATTT AC.GT AAGC.GCTT AACC.GGTT AAAT.ATTT AT.AT AATG.CATT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAAT.ATTTT AAAC.GTTT ACT.AGT AG.CT AT.AT AAAT.ATTT AC.GT AAC.GTT AC.GT AC.GT AT.AT AAAAC.GTTTT AAGG.CCTT AC.GT AAC.GTT AC.GT ACAG.CTGT AC.GT AAAC.GTTT AAAC.GTTT AC.GT AAAC.GTTT AAAT.ATTT AG.CT AC.GT AAAC.GTTT

14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14

79988084 80073785 80707962 80980447 81297619 81327175 81384252 81571230 82266813 82266813 82382897 82382897 82382897 82382897 82410716 82410716 82410716 82410716 82410716 82436676 82772844 82867954 82867954 83043173 83119341 83161330 83462665 83580890 83580890 83954144 84154335 84181988 84456708 85430208 85642623 85808100 85815230 85869613 86020799 86179042 86202923 86379296 86490041 86629343 86717625 86965671 87191553 87508699 87594018 87806828 87927799 87984439 88080627 88133434 88314988 88549551 88589639 88790306 89168391 89182534 89649831 89659847 89889153 89936186 90150739 90207129 90291486 90352338 90399958 90410196 90497879 90508999 90516633 90807495 90834316 90936658 90995703 91315791 91354362 91462365 92048108 92087386 92205970 92396054

79988111 80073795 80707976 80980474 81297641 81327190 81384270 81571253 82266825 82266825 82382908 82382908 82382908 82382908 82410730 82410730 82410730 82410730 82410730 82436685 82772853 82867967 82867967 83043188 83119359 83161359 83462686 83580904 83580904 83954155 84154349 84182006 84456725 85430217 85642635 85808115 85815244 85869622 86020813 86179053 86202933 86379312 86490053 86629364 86717637 86965706 87191594 87508713 87594032 87806840 87927810 87984450 88080658 88133444 88315019 88549565 88589655 88790320 89168406 89182553 89649857 89659859 89889165 89936204 90150751 90207143 90291502 90352349 90399977 90410217 90497890 90509013 90516651 90807507 90834334 90936672 90995721 91315804 91354374 91462385 92048124 92087401 92205979 92396074

7 5.5 7.5 7 7.66667 3.2 3.8 12 6.5 6.5 3 3 3 3 5 5 5 5 5 5 5 7 7 5.33333 3.8 7.5 11 7.5 7.5 4 3.75 4.75 4.5 5 6.5 8 3 5 5 4 5.5 3.4 6.5 5.5 6.5 9 10.5 3.75 3.75 6.5 3 3 8 5.5 8 3.75 4.25 3.75 3.2 5 9 6.5 6.5 4.75 6.5 5 8.5 6 10 4.4 3 7.5 6.33333 6.5 4.75 7.5 4.75 3.5 6.5 5.25 4.25 8 5 5.25

. ENSSSCT00000011248 . . ENSSSCT00000011261 ENSSSCT00000011261 ENSSSCT00000011261 . ENSSSCT00000011271 ENSSSCT00000022350 ENSSSCT00000036513 ENSSSCT00000011274 ENSSSCT00000035011 ENSSSCT00000035106 ENSSSCT00000011274 ENSSSCT00000035011 ENSSSCT00000035106 ENSSSCT00000035374 ENSSSCT00000036513 ENSSSCT00000011275 . ENSSSCT00000011290 ENSSSCT00000011289 ENSSSCT00000011292 ENSSSCT00000011292 ENSSSCT00000011292 . ENSSSCT00000011293 ENSSSCT00000019986 . . . . . . ENSSSCT00000011303 ENSSSCT00000011303 ENSSSCT00000011303 . . . . . . . ENSSSCT00000011305 . . . . . . ENSSSCT00000011307 ENSSSCT00000011307 . ENSSSCT00000028444 . ENSSSCT00000011318 . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000011325 ENSSSCT00000031701

. UNC5B . . MICU1 MICU1 MICU1 . TTC18 TTC18 PPP3CB PPP3CB PPP3CB PPP3CB PPP3CB PPP3CB PPP3CB PPP3CB PPP3CB USP54 . VCL VCL ADK ADK ADK . KAT6B . . . . . . . . . . . . . . . . . POLR3A . . . . . . . . . TMEM254 . DYDC1 . . . . . . . . . . . . . . . . . . . . . . . . GHITM CCSER2

intergenic intron intergenic intergenic intron intron intron intergenic intron intron intron intron intron intron intron intron intron intron intron intron intergenic intron intron intron intron intron intergenic intron promoter intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intron intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic 3'utr intron

. -0.11 . 0.092 . 0.169 0.445 . 0.321 0.321 0.744 0.744 0.744 0.744 0.495 0.495 0.495 0.495 0.495 0.199 . . . . . . . 0.33 0.33 . . . 0.591 . -0.234 . -0.066 0.102 . 0.034 -0.16 0.097 -0.077 -0.133 0.366 0.071 -0.142 0.709 0.123 0.037 -0.267 -0.249 -0.177 -0.182 -0.036 0.238 . -0.108 . . . 0.067 0.201 . -0.092 0.363 0.1 . -0.109 0.652 -0.098 -0.131 -0.156 0.013 . 0.016 0.084 0.324 -0.213 -0.107 . -0.135 0.022 .

rs791069397 rs692948756 rs790974054 rs792662472 548308 rs7879 601147 rs7889 rs791916371 rs793880295 656485 rs7914 656485 rs7914 . . . . rs709062871 rs709062871 rs709062871 rs709062871 rs709062871 . . . . 282633 rs7875 rs792265150 rs789807553 . rs792704379 rs792704379 rs788329588 rs792859739 368371 rs7899 rs793793518 rs787602118 rs789192341 rs789242773 rs787352680 rs789742298 rs793036972 rs789643678 rs792994569 rs789560223 . rs793681674 rs786712708 793750 rs7902 rs787971159 193187 rs7917 . rs791710585 rs790076155 . rs791491388 . rs788717088 165662 rs7879 rs787093511 799282 rs7895 rs792119254 rs788637539 rs790419937 rs789435181 rs789609006 rs791701347 579665 rs7904 rs790494052 rs790682706 781416 rs7002 rs787400110 . . rs788573072 rs786842063 rs790141700 rs787856072 . rs790383143 rs790866372 . 557598 rs7868 rs788991539 rs786212459 . rs786804769

4 2 2 2 2 2 2 2 2 2 2 2 2 2 4 4 4 4 4 2 2 2 2 2 2 2 2 4 4 2 2 2 2 2 2 4 2 2 3 2 2 2 4 2 2 3 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 4 2 2 2 3 2 4 2 2 2 2 2 2 2 4 2 2 4 2 2 2 2 2

AAAC.GTTT AAAAC.GTTTT AAAAC.GTTTT AAAAC.GTTTT AAAAC.GTTTT AT.AT AC.GT AC.GT AT.AT AT.AT AAAAC.GTTTT AC.GT AAAC.GTTT AAAT.ATTT AT.AT AAAC.GTTT AC.GT AAAG.CTTT ACACAT.ATGTGT AATG.CATT AAAC.GTTT AAG.CTT AAG.CTT AG.CT AG.CT AG.CT AAAC.GTTT AAAC.GTTT AC.GT AC.GT AAAAC.GTTTT AAT.ATT AC.GT AAC.GTT AAAG.CTTT AAAC.GTTT AT.AT AT.AT AT.AT AG.CT AC.GT AAG.CTT AG.CT AAC.GTT AAAC.GTTT AATG.CATT AC.GT ACC.GGT AAC.GTT AAAT.ATTT AAAC.GTTT AC.GT AT.AT AAAC.GTTT AT.AT AT.AT AAAC.GTTT AG.CT AGAT.ATCT AT.AT AAAC.GTTT AAAC.GTTT AAC.GTT AAAT.ATTT AAAC.GTTT AT.AT AG.CT AAG.CTT AC.GT AAAAAT.ATTTTT AAAAC.GTTTT AAAT.ATTT AG.CT AAAAAG.CTTTTT AAAC.GTTT AC.GT AC.GT AT.AT AT.AT AAAT.ATTT AC.GT AAAAT.ATTTT AT.AT AAAT.ATTT

14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14

92396054 92398141 92398141 92485911 92485911 92643720 92719156 92829745 92953164 93325443 93483178 93795645 93847917 93988794 95272150 95536449 95599054 95647723 96308749 96726165 96975533 97199323 97199323 97440054 97854520 98027435 98044157 98111632 98521325 98521325 98592958 98633025 98730443 98868066 99670176 99857852 99861498 99864545 99956006 100022843 100067471 100282168 100529761 100667740 100701532 100894636 101162196 101496084 101551959 101581886 101664934 101691517 101742021 101792034 101895978 102542728 102551989 102649493 102733821 102852359 102982258 103021225 103213483 103362014 103540965 103677008 103981747 104036803 104194502 104246333 104295986 104347013 104544963 104605831 104958024 105019560 105037794 105063799 105069922 105145571 105235331 105346500 105373119 105417987

92396074 92398165 92398165 92485926 92485926 92643729 92719177 92829755 92953176 93325459 93483202 93795674 93847931 93988808 95272161 95536473 95599068 95647748 96308787 96726192 96975547 97199336 97199336 97440065 97854531 98027445 98044184 98111652 98521336 98521336 98592983 98633041 98730453 98868083 99670190 99857882 99861527 99864556 99956016 100022869 100067485 100282179 100529777 100667753 100701559 100894651 101162228 101496098 101551971 101581903 101664949 101691534 101742032 101792054 101895988 102542741 102552017 102649516 102733842 102852369 102982285 103021248 103213499 103362035 103540986 103677024 103981759 104036821 104194513 104246353 104296000 104347031 104544972 104605853 104958038 105019572 105037810 105063819 105069931 105145585 105235343 105346523 105373128 105418005

5.25 5 5 3.2 3.2 5 11 5.5 6.5 8.5 5 15 3.75 3.75 6 6.25 7.5 6.5 6.5 7 3.75 4.66667 4.66667 6 6 5.5 7 5.25 6 6 5.2 5.66667 5.5 6 3.75 7.75 15 6 5.5 13.5 7.5 4 8.5 4.66667 7 4 16.5 5 4.33333 4.5 4 9 6 5.25 5.5 7 7.25 12 5.5 5.5 7 6 5.66667 5.5 5.5 8.5 6.5 6.33333 6 3.5 3 4.75 5 3.83333 3.75 6.5 8.5 10.5 5 3.75 6.5 4.8 5 4.75

ENSSSCT00000011332 ENSSSCT00000031701 ENSSSCT00000011332 ENSSSCT00000031701 ENSSSCT00000011332 . . . . . ENSSSCT00000011333 . . ENSSSCT00000022896 ENSSSCT00000011342 . ENSSSCT00000022588 . . ENSSSCT00000011362 ENSSSCT00000011364 ENSSSCT00000026607 ENSSSCT00000011366 . ENSSSCT00000011374 ENSSSCT00000011376 ENSSSCT00000011376 . ENSSSCT00000011380 ENSSSCT00000023429 ENSSSCT00000033578 ENSSSCT00000011385 ENSSSCT00000011386 ENSSSCT00000011387 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000011410 ENSSSCT00000011410 . . . . . . . . . .

CCSER2 CCSER2 CCSER2 CCSER2 CCSER2 . . . . . . . . . BMPR1A . FAM35A . . MAPK8 . WDFY4 WDFY4 . DRGX CHAT CHAT . PARG . MSMB . ZFAND4 8-Mar . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PCDH15 PCDH15 . . . . . . . . . .

intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intron intron intergenic promoter intergenic intergenic intron intron intron intron intergenic intron intron intron intergenic intron promoter intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

. . . 0.462 0.462 0.083 -0.16 0.067 -0.01 . -0.057 0.049 0.123 -0.249 -0.146 -1.228 . . . 0.328 -0.166 -0.032 -0.032 -0.317 . 0.057 . 0.362 -0.191 -0.191 . . 0.152 . 0.011 0.131 . 0.158 -0.083 . -0.477 -0.001 . . . 0.079 0.017 . 0.325 0.042 . . . . -0.104 0.11 0.176 . 0.052 . . -0.089 . . . -0.128 -0.236 -0.068 . . . . 0.035 -0.163 0.016 . 0.185 0.189 0.56 0.161 . . 0.196 -0.195

rs786804769 rs788469148 rs788469148 rs787290101 rs787290101 . rs786644501 . rs792209537 458113 rs7921 rs702369505 773179 rs7867 135552 rs7904 rs793086732 rs701455741 rs787861184 rs791214122 699004 rs7932 rs791343162 181931 rs7919 rs793612040 rs792651729 rs792651729 164255 rs7888 rs792323172 rs791707032 rs786407113 616341 rs7921 324687 rs7896 324687 rs7896 384817 rs7885 rs793283629 rs793262236 999189 rs6907 rs786338411 rs791447062 133677 rs7873 rs787349911 084933 rs7879 rs793354657 . . rs789087903 800333 rs7919 rs789375958 rs789490802 rs787691380 280305 rs7923 rs792074434 rs788126197 rs788074911 rs793882437 215311 rs7909 rs788728116 rs697260293 418918 rs7878 . rs789833803 rs792076121 rs792431709 rs792482719 rs789970035 rs698917760 . 988414 rs7916 . . rs792131669 rs791946096 843644 rs7865 145957 rs7890 rs787512565 . rs790506981 rs789198168 rs788378544 . rs791979319 . rs791063792 rs791178100 rs789046372 . .

2 2 2 2 2 3 2 6 2 2 2 2 2 2 3 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 4 2 2 2 2 2 2 2 3 2 3 2 2 2 2 3 2 2 2 2 2 2 3 2 3 2 2 2 3 2 2 2 2 2 3 2 2 2 2 2 2 2 3 2 3 3

AAAC.GTTT ACC.GGT AC.GT AAAAT.ATTTT AG.CT AAAT.ATTT AATG.CATT AAAAAC.GTTTTT AAAC.GTTT AC.GT AACC.GGTT AAAAC.GTTTT AAAAC.GTTTT AGC.GCT AAAT.ATTT AT.AT AC.GT AC.GT AG.CT AAAC.GTTT AATG.CATT AT.AT AC.GT AC.GT AC.GT AT.AT AAAAG.CTTTT AC.GT AAAT.ATTT AC.GT AAAAAG.CTTTTT AC.GT ACAT.ATGT AAT.ATT AT.AT AAAAAC.GTTTTT AAC.GTT ACC.GGT AG.CT AAAC.GTTT AC.GT AAAAC.GTTTT AAG.CTT AAAC.GTTT AGAT.ATCT AAAAC.GTTTT AAAG.CTTT AT.AT AGG.CCT AAAAAC.GTTTTT AAAC.GTTT AAAT.ATTT AAGC.GCTT AAAAAC.GTTTTT AAC.GTT AAAAAC.GTTTTT AT.AT AAC.GTT AGG.CCT AAC.GTT AAAC.GTTT AT.AT AAAC.GTTT AT.AT AC.GT AC.GT AT.AT AT.AT AT.AT AC.GT ACC.GGT ACAT.ATGT AT.AT AAAAC.GTTTT AAACC.GGTTT ACT.AGT ACC.GGT AATG.CATT AT.AT AAAC.GTTT AAAC.GTTT AAGG.CCTT AAC.GTT AT.AT

14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14

105423019 105441814 105938690 105987158 106069457 106290309 106335018 106708929 106794351 106803249 106821751 106865044 106878055 107457176 107491601 107552754 107581331 107590297 107593842 107608459 107612750 107650813 107728077 107770901 107903001 108063640 108176575 108308328 108323243 108381254 108408625 109378760 109378828 109569967 109707091 109979984 110000453 110024315 110030526 110079098 110297591 110700418 110927387 111250580 111655911 111775923 111782852 111949889 111987791 112573831 113079098 113095299 113391327 113857294 113885223 114093895 114505493 114557261 114574592 114594570 114819757 114887484 114939005 115004717 115491792 115556913 115633931 115633931 115853912 116524317 116687490 117030103 117269925 117303371 117522398 117649306 118061840 118260488 118282574 118408972 118408972 118462387 118649493 118898565

105423038 105441827 105938700 105987172 106069473 106290336 106335045 106708951 106794378 106803259 106821773 106865071 106878078 107457192 107491623 107552767 107581352 107590308 107593851 107608477 107612772 107650823 107728087 107770917 107903014 108063649 108176596 108308340 108323269 108381273 108408648 109378778 109378841 109569981 109707100 109980006 110000475 110024332 110030538 110079124 110297619 110700441 110927402 111250596 111655929 111775941 111782870 111949913 111987804 112573851 113079112 113095315 113391349 113857322 113885235 114093921 114505503 114557277 114574606 114594583 114819774 114887502 114939019 115004726 115491821 115556934 115633944 115633944 115853925 116524329 116687507 117030114 117269935 117303397 117522416 117649317 118061855 118260505 118282587 118408990 118408990 118462404 118649508 118898575

5 4.66667 5.5 3 8.5 7 7 3.83333 7 5.5 5.75 5.6 4.8 5.66667 5.75 7 11 6 5 4.75 5.75 5.5 5.5 8.5 7 5 4.4 6.5 6.75 10 4 9.5 3.5 5 5 3.83333 7.66667 6 6.5 6.75 14.5 4.8 5.33333 4.25 4.75 3.8 4.75 12.5 4.66667 3.5 3.75 4.25 5.75 4.83333 4.33333 4.5 5.5 5.66667 5 4.66667 4.5 9.5 3.75 5 15 11 7 7 7 6.5 6 3 5.5 5.4 3.8 4 5.33333 4.5 7 4.75 4.75 4.5 5.33333 5.5

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011414 PRKG1 intron ENSSSCT00000011414 PRKG1 intron ENSSSCT00000011414 PRKG1 promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000027836 . intron ENSSSCT00000027836 . intron ENSSSCT00000027836 . intron ENSSSCT00000027836 . intron ENSSSCT00000027836 . intron ENSSSCT00000027836 . intron ENSSSCT00000027836 . intron . . intergenic . . intergenic ENSSSCT00000011417 . intron ENSSSCT00000011418 SGMS1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011445 HTR7 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011455 . intron ENSSSCT00000011455 . intron . . intergenic . . intergenic . . intergenic ENSSSCT00000011461 . intron ENSSSCT00000011464 . intron ENSSSCT00000011464 . intron ENSSSCT00000011464 . intron ENSSSCT00000011464 . intron ENSSSCT00000011468 PDE6C intron ENSSSCT00000031763 FRA10AC1 intron . . intergenic . . intergenic ENSSSCT00000011471 PLCE1 intron ENSSSCT00000011471 PLCE1 intron ENSSSCT00000032028 NOC3L intron ENSSSCT00000011472 NOC3L intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011493 BLNK intron ENSSSCT00000011493 BLNK intron . . intergenic ENSSSCT00000011498 TM9SF3 intron . . intergenic ENSSSCT00000011504 RRP12 intron . . intergenic ENSSSCT00000027226 UBTD1 intron ENSSSCT00000011511 UBTD1 intron ENSSSCT00000011513 HOGA1 promoter . . intergenic ENSSSCT00000011521 R3HCC1L intron

-0.027 . -0.061 . 0.043 -0.014 0.03 -0.05 0.179 -0.153 0.044 0.255 -0.097 0.11 0.185 -0.022 1.253 . 0.176 -0.19 -0.042 0.123 -0.046 -0.056 0.437 0.021 -0.095 0.369 -0.168 -0.045 0.174 0.049 0.032 0.085 -0.036 . 0 -0.114 -0.031 -0.036 0.308 0.154 . . . . -0.11 0.098 -0.009 . . 0.266 0.057 0.124 . . 1.093 0.241 0.026 0.003 . . 0.072 . 0.165 0.042 . . . -0.212 0.246 0.164 . 0.795 1.065 0.158 0.495 1.016 0.358 -0.011 -0.011 -0.092 -0.121 0.315

rs789696022 . 134951 rs7892 . . 294540 rs7872 rs792930340 696042 rs7864 rs692239853 rs791772307 rs793585100 rs787784747 . 331774 rs7896 rs786423762 rs787378793 rs788578249 . 726989 rs7927 rs788935657 rs786829744 . rs789279910 946345 rs7931 rs792039466 rs793620830 206631 rs7876 rs787840612 893240 rs7901 686799 rs7884 rs792145478 . 887274 rs7902 rs788381207 rs787704779 . rs789148338 rs698361527 rs789092955 000779 rs7881 rs793751433 rs700669677 rs706636575 rs787674820 rs787651446 rs789568607 rs789250806 rs787986359 rs792142342 rs793203088 rs790417532 rs705196049 040556 rs7908 153678 rs7877 rs792646611 745228 rs7938 rs791845277 041506 rs7884 rs791316818 729927 rs7901 rs792741937 rs793724923 510025 rs7903 266687 rs7897 334012 rs7871 rs712757476 rs790359886 rs790359886 rs793798219 308071 rs7938 368440 rs7895 . rs788791413 172958 rs7898 rs793393327 . rs791251930 rs786905432 rs792330472 rs793471726 rs793471726 rs788623068 . rs789009323

3 2 3 2 4 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 4 2 2 5 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 3 2 2 3 2 2 2 3 2 2 4 4 2 2 2 3 2 2 2 2 2 2 2 3 3 2 2 2 2 2

AC.GT AAG.CTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AG.CT AAC.GTT AT.AT AC.GT AG.CT AAAT.ATTT AAAC.GTTT AATG.CATT AAAC.GTTT AAAC.GTTT AATG.CATT AAAAAC.GTTTTT AAC.GTT AG.CT AG.CT AAT.ATT AAAC.GTTT AC.GT AAAC.GTTT AAAAAC.GTTTTT AAAAC.GTTTT AAAC.GTTT AT.AT AGGGG.CCCCT AAAT.ATTT AAAAC.GTTTT AC.GT AT.AT AG.CT AAAAT.ATTTT AG.CT AAC.GTT AAAAC.GTTTT AAAC.GTTT AAACC.GGTTT ATC.GAT AACAT.ATGTT AAAG.CTTT AAC.GTT AAC.GTT AAAC.GTTT AC.GT AG.CT AGG.CCT AGC.GCT AAAAC.GTTTT AAT.ATT AC.GT AAGG.CCTT AAAC.GTTT AC.GT AT.AT AAAAC.GTTTT AAAAC.GTTTT AC.GT AT.AT AC.GT AC.GT AC.GT AAC.GTT AC.GT AAAG.CTTT AAT.ATT AAAAC.GTTTT AAAAC.GTTTT AAAAC.GTTTT AAAAC.GTTTT AAAAC.GTTTT AAAAC.GTTTT AAAAC.GTTTT AC.GT AC.GT AC.GT AC.GT AC.GT AC.GT AGG.CCT AGG.CCT AGG.CCT

14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14

118901816 119014723 119067026 119239711 119322182 119365646 119430253 119481458 119624100 119916725 120071347 120189675 120240636 120367606 120393238 120450868 120466290 120498474 120543982 120859741 120891363 121302844 121404084 121445300 121945031 122108588 122159299 122190322 122326979 122405679 122406782 122714560 122833681 122835007 122906716 123787273 124554069 124576072 124722826 124802367 124803353 124834121 124870127 124953709 125196158 125252589 125278483 125584945 125812228 126065383 126194364 126198191 126285097 126290094 126476072 126480669 127012927 127117986 127170584 127177753 127199743 127211656 127217902 127282937 127283321 127370080 127546472 127749028 127985871 127985871 127985871 127985871 127985871 127985871 127985871 128142382 128142382 128142382 128142382 128142382 128142382 128173537 128173537 128173537

118901830 119014737 119067044 119239725 119322202 119365657 119430277 119481467 119624112 119916737 120071366 120189695 120240654 120367624 120393264 120450888 120466310 120498492 120543995 120859751 120891388 121302864 121404103 121445322 121945059 122108603 122159317 122190340 122326998 122405697 122406804 122714569 122833691 122835019 122906735 123787282 124554082 124576094 124722844 124802391 124803370 124834136 124870149 124953727 125196177 125252609 125278494 125584956 125812240 126065399 126194378 126198206 126285107 126290114 126476094 126480683 127012937 127118002 127170610 127177768 127199761 127211678 127217920 127282955 127283351 127370090 127546486 127749053 127985889 127985889 127985889 127985889 127985889 127985889 127985889 128142403 128142403 128142403 128142403 128142403 128142403 128173553 128173553 128173553

7.5 5 4.75 3.75 5.25 6 8.33333 5 6.5 6.5 5 5.25 4.75 4.75 6.75 5.25 3.5 6.33333 7 5.5 8.66667 5.25 10 5.75 4.83333 3.2 4.75 9.5 4 4.75 4.6 5 5.5 6.5 4 5 4.66667 4.6 4.75 5 6 3.2 5.75 6.33333 6.66667 5.25 6 6 4.33333 5.66667 3 5.33333 5.5 5.25 5.75 7.5 5.5 3.4 5.4 8 9.5 11.5 9.5 9.5 10.3333 5.5 3.75 8.66667 3.8 3.8 3.8 3.8 3.8 3.8 3.8 11 11 11 11 11 11 5.66667 5.66667 5.66667

ENSSSCT00000011521 . . . ENSSSCT00000011525 ENSSSCT00000011525 . . . . ENSSSCT00000011527 . . . . ENSSSCT00000011534 ENSSSCT00000011534 ENSSSCT00000011535 ENSSSCT00000011535 ENSSSCT00000011542 ENSSSCT00000011542 ENSSSCT00000011547 . . . . ENSSSCT00000011555 ENSSSCT00000011555 ENSSSCT00000011555 ENSSSCT00000011558 ENSSSCT00000011558 ENSSSCT00000011562 ENSSSCT00000011564 ENSSSCT00000011564 ENSSSCT00000011564 . . . . . . ENSSSCT00000011602 ENSSSCT00000011602 . ENSSSCT00000011608 . ENSSSCT00000011610 . . ENSSSCT00000011613 . . . . . . . . . . . . . . . . . . ENSSSCT00000033867 ENSSSCT00000034837 ENSSSCT00000034800 ENSSSCT00000032873 ENSSSCT00000026529 ENSSSCT00000034580 ENSSSCT00000035864 ENSSSCT00000033867 ENSSSCT00000034837 ENSSSCT00000034800 ENSSSCT00000032873 ENSSSCT00000034580 ENSSSCT00000035864 ENSSSCT00000033867 ENSSSCT00000034837 ENSSSCT00000034800

R3HCC1L . . . HPSE2 HPSE2 . . . . GOT1 . . . . ABCC2 ABCC2 DNMBP DNMBP CWF19L1 CWF19L1 HIF1AN . . . . BTRC BTRC BTRC FBXW4 FBXW4 KCNIP2 C10orf76 C10orf76 C10orf76 . . . . . . SLK SLK . . . CCDC147 . . SORCS3 . . . . . . . . . . . . . . . . . . SORCS1 SORCS1 SORCS1 SORCS1 SORCS1 SORCS1 SORCS1 SORCS1 SORCS1 SORCS1 SORCS1 SORCS1 SORCS1 SORCS1 SORCS1 SORCS1

intron intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intron intron intron intron intron promoter intron intergenic intergenic intergenic intergenic intron intron 3'utr intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intron 3'utr intergenic intron intergenic intron intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intron intron intron intron intron intron intron intron intron intron

0.199 0.081 -0.257 0.118 0.079 . 0.234 . . 0.513 0.182 0.093 -0.167 0.224 . . 0.558 -0.058 0.404 0.178 0.302 . -0.061 0.053 -0.099 . 0.297 0.375 1.844 . . 0.18 0.09 0.446 . . -0.064 . 0.063 0.123 . 0.263 0.87 . . 0.379 -0.105 -0.103 -0.059 0.491 -0.277 0.019 -0.064 -0.143 -0.035 -0.182 . . -0.007 -0.033 -0.027 . . -0.091 -0.33 -0.125 . 0.057 -0.079 -0.079 -0.079 -0.079 -0.079 -0.079 -0.079 0.758 0.758 0.758 0.758 0.758 0.758 -0.11 -0.11 -0.11

rs789484336 342991 rs7866 040451 rs7864 rs791835811 085816 rs7935 rs790040572 rs792849015 rs788706902 . . rs792271819 rs791547111 rs789116003 252025 rs7862 rs789117889 rs786642206 180495 rs7866 rs787518318 rs788707019 . rs787918365 rs786209295 rs790191413 rs793370237 rs788392920 . 340511 rs7866 . 853888 rs7933 rs793299212 rs786408174 . . rs791035938 rs787621523 . rs693209044 rs787698717 156998 rs7915 810136 rs7932 681811 rs7924 458110 rs7905 837108 rs7874 rs793202717 rs787596396 rs793875581 rs786474874 rs792192136 rs787423546 . rs789628983 623765 rs7889 . rs791080255 227797 rs7926 780758 rs7878 rs790267295 rs788813745 718106 rs7871 rs786395924 rs791260306 rs787195489 . rs789054436 679303 rs7929 rs701905227 . 596249 rs7934 rs793554040 rs793554040 rs793554040 rs793554040 rs793554040 rs793554040 rs793554040 rs792692119 rs792692119 rs792692119 rs792692119 rs792692119 rs792692119 . . .

3 2 2 2 3 4 2 2 2 3 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 3 4 2 2 2 3 2 2 2 4 2 2 2 2 2 2 2 2 2 2 4 3 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2

AGG.CCT AGG.CCT AGG.CCT AC.GT AC.GT AC.GT AC.GT AC.GT AC.GT AACC.GGTT AATT.AATT AG.CT AC.GT AC.GT AC.GT AG.CT AAC.GTT AT.AT AAAC.GTTT AC.GT AAAT.ATTT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AAAAAC.GTTTTT AAAC.GTTT AAAT.ATTT AAAC.GTTT AAT.ATT AC.GT AG.CT AAAC.GTTT AC.GT AAC.GTT AC.GT AAAC.GTTT AC.GT AAAT.ATTT AAAC.GTTT AAAAT.ATTTT ACGC.GCGT AGG.CCT AGAT.ATCT AAAC.GTTT AAAG.CTTT AAC.GTT AC.GT AT.AT AATC.GATT AG.CT AT.AT AAAG.CTTT AGGG.CCCT AAAAAG.CTTTTT AC.GT AAGAG.CTCTT AC.GT AT.AT AAAC.GTTT AGC.GCT AAAG.CTTT AAAAC.GTTTT ATC.GAT AG.CT AT.AT AAC.GTT AAC.GTT AC.GT AT.AT AT.AT AAGG.CCTT AT.AT AT.AT AAC.GTT AAC.GTT AAT.ATT AAT.ATT AAAG.CTTT AAAG.CTTT AAAAT.ATTTT AG.CT AC.GT AAC.GTT AT.AT

14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14

128173537 128173537 128173537 128203044 128203044 128203044 128203044 128203044 128203044 128398599 128888242 128909642 129183649 129427195 129439839 129747941 129751987 129900364 129936756 130089656 130205241 130370709 130420255 130439463 130513951 130727746 130771078 130978847 131086391 131101101 131123069 131300445 131406600 131437560 131681037 131731559 131911509 131917580 131956028 131994908 132043429 132266364 132509450 132563949 132597529 132754347 132755146 132834708 132918427 133055554 133100105 133119554 133197342 133262039 133534443 134243290 134719860 134816149 134969851 135058500 135072952 135329922 135405515 135452710 135519560 135558128 135582756 135640640 135984017 136086450 136157156 136585208 136585208 136586085 136586085 136669884 136669884 136709472 136709472 136846474 136968878 137019383 137089312 137131150

128173553 128173553 128173553 128203058 128203058 128203058 128203058 128203058 128203058 128398618 128888268 128909651 129183680 129427221 129439854 129747955 129752011 129900374 129936771 130089665 130205273 130370727 130420269 130439480 130513984 130727758 130771093 130978866 131086425 131101112 131123078 131300457 131406617 131437576 131681061 131731582 131911521 131917601 131956046 131994926 132043446 132266379 132509469 132563963 132597542 132754360 132755159 132834728 132918454 133055564 133100114 133119567 133197359 133262065 133534453 134243307 134719897 134816162 134969865 135058514 135072977 135329952 135405528 135452724 135519581 135558147 135582771 135640651 135984028 136086468 136157189 136585223 136585223 136586101 136586101 136669895 136669895 136709491 136709491 136846489 136968890 137019394 137089344 137131159

5.66667 5.66667 5.66667 7.5 7.5 7.5 7.5 7.5 7.5 5 6.75 5 16 13.5 8 7.5 8.33333 5.5 4 5 8.25 4.75 3.75 3.6 5.66667 3.25 4 5 11.6667 6 5 3.25 9 5.66667 12.5 6 6.5 5.5 4.75 3.8 4.5 5.33333 5 3.75 3.5 4.66667 7 10.5 7 5.5 5 3.5 4.5 4.5 5.5 3.6 19 7 3.75 5 6.5 6.2 4.66667 7.5 11 6.66667 5.33333 6 6 9.5 8.5 8 8 5.66667 5.66667 4 4 5 5 3.2 6.5 6 11 5

ENSSSCT00000032873 ENSSSCT00000034580 ENSSSCT00000035864 ENSSSCT00000033867 ENSSSCT00000034837 ENSSSCT00000034800 ENSSSCT00000032873 ENSSSCT00000034580 ENSSSCT00000035864 . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000011616 ENSSSCT00000011617 ENSSSCT00000011617 . . . . . . . . ENSSSCT00000025919 . . . . . . . . . . . . . . ENSSSCT00000011635 . . . . ENSSSCT00000011644 . . ENSSSCT00000011646 . . ENSSSCT00000011647 ENSSSCT00000011650 ENSSSCT00000011650 . ENSSSCT00000032203 ENSSSCT00000011653 ENSSSCT00000032203 ENSSSCT00000011653 ENSSSCT00000032203 ENSSSCT00000011653 ENSSSCT00000032203 ENSSSCT00000011653 ENSSSCT00000032203 . . . .

SORCS1 SORCS1 SORCS1 SORCS1 SORCS1 SORCS1 SORCS1 SORCS1 SORCS1 . . . . . . . . . . . . . . . . . . . . . XPNPEP1 ADD3 ADD3 . . . . . . . . . . . . . . . . . . . . . . . TCF7L2 . . . . . . . ADRB1 . . C10orf118 ABLIM1 ABLIM1 . ATRNL1 ATRNL1 ATRNL1 ATRNL1 ATRNL1 ATRNL1 ATRNL1 ATRNL1 ATRNL1 . . . .

intron intron intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intron intergenic intergenic promoter intergenic intergenic intron intron intron intergenic intron intron intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic

-0.11 -0.11 -0.11 -0.32 -0.32 -0.32 -0.32 -0.32 -0.32 0.359 . -0.183 . -0.193 . . . 0.148 0.223 . . . . . 0.033 -0.134 0.076 0.021 1.494 0.188 -0.176 0.447 0.147 0.051 -0.085 -0.234 0.33 . 0.007 -0.057 0.007 0.115 0.079 -0.334 . -0.137 -0.028 . 0.123 -0.117 -0.558 0.004 0.093 0.102 . . 0.67 -0.007 -0.143 0 0.083 . 0.054 -0.141 0.298 0.253 . 0.08 -0.041 . 0.039 . . . . . . 0.374 0.374 . . -0.048 . 0.026

. . . . . . . . . 167089 rs7906 rs790250139 386356 rs7866 rs694951115 . . rs788911720 502965 rs7890 rs694790927 841259 rs7902 801527 rs7929 . . rs791334539 037042 rs7877 rs792459125 rs788417306 rs792037296 rs790638832 rs786944832 . . rs793717325 rs788032262 455825 rs7882 rs790244257 rs793202512 rs792535956 rs788096666 055875 rs7892 rs787454130 518249 rs7930 150061 rs7880 rs789317961 rs793544187 rs788770045 rs790406841 rs787670132 rs792604405 391143 rs7916 rs791101010 rs791229650 . 328305 rs7896 619437 rs7039 576447 rs7923 714170 rs7876 . rs789638631 rs787674942 . 602554 rs7922 922100 rs7901 rs790925042 . 821700 rs7878 rs792603298 rs792346789 rs787720560 rs789983681 rs788032883 rs788102461 579722 rs7917 579722 rs7917 201490 rs7917 201490 rs7917 rs793862343 rs793862343 717924 rs7925 717924 rs7925 rs790266147 . 870599 rs7873 286373 rs7927 rs790812728

2 2 2 3 3 3 3 3 3 2 2 3 4 4 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 4 2 2 2 2 2 4 2 2 2 2 2 2 6 2 4 4 2 2 2 2 2 2 3 3 2 2 2 3 2 2 3 2 3 2 2 2 4 2 2 2 2 3 3 2 2 2 2 2 2 2

AAAAC.GTTTT AC.GT AC.GT AACAC.GTGTT AAT.ATT AAAT.ATTT AATG.CATT AAC.GTT AAAT.ATTT AAT.ATT AAAC.GTTT AC.GT AAAAC.GTTTT AG.CT AAAT.ATTT AT.AT AAAC.GTTT AC.GT AC.GT AT.AT AAG.CTT AT.AT AC.GT AT.AT ATCC.GGAT ATCC.GGAT AC.GT AG.CT AT.AT AAGC.GCTT AC.GT AAAC.GTTT AAAG.CTTT AAAAAC.GTTTTT AAAAT.ATTTT AAG.CTT AAAC.GTTT AAAC.GTTT AAAT.ATTT AC.GT AC.GT AC.GT AAAC.GTTT AC.GT AAAC.GTTT AGG.CCT AG.CT AG.CT AGGG.CCCT AGGG.CCCT AGGG.CCCT AGGG.CCCT AGGG.CCCT AGGG.CCCT AGGG.CCCT AGGG.CCCT ATCC.GGAT ATCC.GGAT ATCC.GGAT ATCC.GGAT ATCC.GGAT ATCC.GGAT ATCC.GGAT ATCC.GGAT ATCC.GGAT ATCC.GGAT AAAAC.GTTTT AC.GT AAAAC.GTTTT AAAAAC.GTTTTT AC.GT AAT.ATT AAAAGC.GCTTTT AT.AT ATCC.GGAT AT.AT AT.AT AC.GT AC.GT AG.CT AC.GT AAAT.ATTT AAC.GTT AC.GT

14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14

137200199 137214977 137248721 137502657 137547162 137585171 137921886 137945226 137976791 138164546 138412122 138526992 138912961 138921640 138971146 139085725 139095682 139330725 139590043 139677316 139682159 139731415 139744331 139784283 139837932 139981861 140205779 140208359 140217676 140284624 140444876 140670705 140701901 140703401 140819316 140982667 141055944 141132515 141299420 141535497 141644981 141674001 141862139 142000537 142097645 142288992 142376511 142424998 142503749 142503749 142503749 142503749 142503749 142503749 142503749 142503749 142535400 142535400 142535400 142535400 142535400 142535400 142535400 142535400 142535400 142535400 142821353 142835110 142894050 143519950 143526896 144252883 144318818 144401311 144409808 144702509 144765075 144988261 145784030 145789795 145800366 146398871 146492762 146847678

137200228 137214987 137248732 137502673 137547180 137585186 137921918 137945239 137976804 138164559 138412138 138527009 138912979 138921650 138971162 139085734 139095697 139330739 139590055 139677332 139682176 139731428 139744342 139784298 139837949 139981880 140205803 140208368 140217686 140284640 140444885 140670736 140701927 140703424 140819341 140982681 141055970 141132533 141299452 141535512 141644997 141674013 141862153 142000549 142097656 142289007 142376522 142425009 142503762 142503762 142503762 142503762 142503762 142503762 142503762 142503762 142535442 142535442 142535442 142535442 142535442 142535442 142535442 142535442 142535442 142535442 142821373 142835124 142894073 143519974 143526909 144252898 144318837 144401323 144409851 144702520 144765085 144988283 145784041 145789808 145800388 146398886 146492785 146847691

6 5.5 6 3.4 6.33333 4 8.25 4.66667 3.5 4.66667 4.25 9 3.8 5.5 4.25 5 4 7.5 6.5 8.5 6 7 6 8 4.5 5 12.5 5 5.5 4.25 5 8 6.75 4 5.2 5 6.75 4.75 8.25 8 8.5 6.5 3.75 6.5 3 5.33333 6 6 3.5 3.5 3.5 3.5 3.5 3.5 3.5 3.5 10.75 10.75 10.75 10.75 10.75 10.75 10.75 10.75 10.75 10.75 4.2 7.5 4.8 4.16667 7 5.33333 3.33333 6.5 11 6 5.5 11.5 6 7 11.5 4 8 7

. . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011654 . intron ENSSSCT00000011654 . intron . . intergenic . . intergenic . . intergenic ENSSSCT00000011663 . intron ENSSSCT00000011666 KIAA1598 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011673 RAB11FIP2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000023068 . intron ENSSSCT00000023068 . intron ENSSSCT00000023068 . intron . . intergenic . . intergenic ENSSSCT00000011684 GRK5 intron ENSSSCT00000011684 GRK5 intron ENSSSCT00000011684 GRK5 intron ENSSSCT00000011684 GRK5 intron ENSSSCT00000011686 . intron ENSSSCT00000011687 BAG3 intron ENSSSCT00000011688 INPP5F intron ENSSSCT00000011691 . intron . . intergenic . . intergenic . . intergenic ENSSSCT00000011692 PPAPDC1A intron . . intergenic . . intergenic ENSSSCT00000011693 . intron . . intergenic . . intergenic ENSSSCT00000036109 FGFR2 intron ENSSSCT00000035425 FGFR2 intron ENSSSCT00000033576 FGFR2 intron ENSSSCT00000033651 FGFR2 intron ENSSSCT00000033270 FGFR2 intron ENSSSCT00000011702 FGFR2 intron ENSSSCT00000032653 FGFR2 intron ENSSSCT00000033856 FGFR2 intron ENSSSCT00000032653 FGFR2 intron ENSSSCT00000033856 FGFR2 intron ENSSSCT00000035980 FGFR2 intron ENSSSCT00000035159 FGFR2 intron ENSSSCT00000036109 FGFR2 intron ENSSSCT00000035425 FGFR2 intron ENSSSCT00000033270 FGFR2 intron ENSSSCT00000011702 FGFR2 intron ENSSSCT00000033576 FGFR2 intron ENSSSCT00000033651 FGFR2 intron ENSSSCT00000011705 ATE1 intron ENSSSCT00000011705 ATE1 intron . . intergenic ENSSSCT00000011709 HTRA1 intron ENSSSCT00000011709 HTRA1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011739 CPXM2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000011757 FANK1 intron

0.362 -0.146 -0.07 . 0.319 . -0.296 0.251 0.108 . -0.125 0.645 0.05 . 0.006 0.06 -0.176 0.352 0.443 0.162 1.94 0.035 0.11 1.294 0.004 0.139 . 0.053 0.103 -0.166 . -0.148 . 0.071 -0.34 0.041 0.154 0.305 . . -0.165 -0.003 . -0.024 . -0.217 0.144 -0.198 -0.077 -0.077 -0.077 -0.077 -0.077 -0.077 -0.077 -0.077 -0.22 -0.22 -0.22 -0.22 -0.22 -0.22 -0.22 -0.22 -0.22 -0.22 0.119 . . -0.402 -0.2 -0.068 . -0.028 -0.036 . . 0.152 0.142 -0.09 -0.032 -0.063 0.002 0.159

rs695589149 rs789674459 rs702446103 458225 rs7883 rs792827803 rs793605989 . rs791843766 rs790591097 rs787547669 rs789179311 rs792459179 rs789598444 rs789440631 rs791256751 195529 rs7879 rs792218735 rs787474716 703138 rs7877 rs793283664 rs792531021 . rs788409927 813304 rs7904 rs790258959 rs789215315 341455 rs7919 . rs793783198 685545 rs7924 rs788377222 778424 rs7923 594811 rs7924 234869 rs7902 . . rs786437605 rs792154506 779960 rs7862 rs791627779 rs792170167 rs786635185 136091 rs7923 444030 rs7865 rs790643193 . rs787016329 . rs786761694 rs786761694 rs786761694 rs786761694 rs786761694 rs786761694 rs786761694 rs786761694 322781 rs7926 322781 rs7926 322781 rs7926 322781 rs7926 322781 rs7926 322781 rs7926 322781 rs7926 322781 rs7926 322781 rs7926 322781 rs7926 rs786769470 670395 rs7899 rs790658812 rs791393909 rs707819821 rs789390171 rs787779039 . rs791077414 rs786688565 rs787302541 rs793738220 rs791480491 rs787045842 . . . 414173 rs7900

2 2 3 2 2 2 2 3 2 2 2 2 2 2 2 3 2 2 2 3 2 2 2 3 2 2 2 4 4 2 2 2 3 2 2 3 3 2 2 2 3 5 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 3 3 2 3 2 2 2 2 3 2 4 3

AAAAT.ATTTT AAAC.GTTT AAC.GTT AAAC.GTTT AG.CT ACTC.GAGT AAAC.GTTT AAAC.GTTT AAAT.ATTT AG.CT AAGG.CCTT AAC.GTT AC.GT AC.GT AC.GT AC.GT AG.CT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAAAC.GTTTTT AAAAT.ATTTT AT.AT AAAAC.GTTTT AC.GT AC.GT AACAC.GTGTT ATC.GAT AG.CT AAAT.ATTT AT.AT AG.CT AG.CT AG.CT AC.GT AT.AT AAAT.ATTT AAAT.ATTT AAAC.GTTT AAAT.ATTT AT.AT AT.AT AC.GT AT.AT AATG.CATT AAG.CTT AC.GT AGAT.ATCT AAAAC.GTTTT AAAC.GTTT AAT.ATT AAAC.GTTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAGG.CCTT AG.CT AAC.GTT AT.AT AAC.GTT AG.CT AT.AT AAAC.GTTT AAAT.ATTT AC.GT AC.GT AG.CT AC.GT AAAAAG.CTTTTT AT.AT AAAC.GTTT AAAAC.GTTTT AAGG.CCTT AAAAC.GTTTT AAC.GTT AAAAAC.GTTTTT AG.CT AAAAC.GTTTT AT.AT AAAT.ATTT AT.AT AG.CT AAAC.GTTT AATG.CATT

14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15

147098871 147678990 147796675 147901415 148006490 148316495 148360099 148890663 149238217 149570043 150784352 150836535 151168207 151409919 151415410 151486359 151532287 153137638 161163 212488 240548 790821 1029658 1043446 1154286 1365403 1419055 1807007 2429787 2598638 2622808 2721470 2755595 2827275 2829785 3009046 3289469 3331183 3558394 3734152 3744124 3838006 3914338 3970620 4436490 4703298 4869811 4877175 5015885 5402904 5454254 5508752 5652854 5655216 5744516 5854793 5934573 6140860 6344033 6344195 6499505 6555027 6759992 6821870 6836364 6846291 6975497 7121414 7225354 7264731 7289148 7322024 7333352 7335323 7485500 7527112 7549362 7590331 7664756 8563937 8867917 8882348 8891178 9076648

147098895 147679008 147796693 147901429 148006499 148316512 148360112 148890681 149238236 149570060 150784369 150836548 151168216 151409930 151415420 151486372 151532303 153137654 161182 212502 240566 790836 1029668 1043470 1154301 1365415 1419070 1807027 2429797 2598655 2622823 2721481 2755606 2827285 2829811 3009056 3289484 3331200 3558410 3734167 3744142 3838017 3914359 3970630 4436506 4703309 4869827 4877188 5015908 5402922 5454279 5508766 5652872 5655240 5744536 5854820 5934582 6140879 6344043 6344214 6499516 6555036 6760007 6821886 6836382 6846303 6975507 7121425 7225374 7264742 7289169 7322048 7333367 7335352 7485518 7527141 7549377 7590359 7664774 8563957 8867927 8882357 8891195 9076677

5 4.75 6.33333 3.75 5 4.5 3.5 4.75 5 9 4.5 4.66667 5 6 5.5 7 8.5 4.25 5 3.75 3.16667 3.2 5.5 5 8 6.5 3.2 7 5.5 4.5 8 6 6 5.5 13.5 5.5 4 4.5 4.25 4 9.5 6 11 5.5 4.25 4 8.5 3.5 4.8 4.75 8.66667 3.75 4.75 6.25 5.25 7 5 6.66667 5.5 6.66667 6 5 4 4.25 9.5 6.5 5.5 6 3.5 6 5.5 5 4 6 6.33333 5 8 5.8 9.5 5.25 5.5 5 4.5 7.5

. . . . . . . . . . ENSSSCT00000011768 ENSSSCT00000011768 . . . . . ENSSSCT00000011784 . . . . . . . . . . . . . . ENSSSCT00000023118 ENSSSCT00000023118 ENSSSCT00000023118 ENSSSCT00000028524 . . . . . ENSSSCT00000017067 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000017069 ENSSSCT00000027823 ENSSSCT00000027823 ENSSSCT00000027823 ENSSSCT00000017070

. . . . . . . . . . MGMT MGMT . . . . . KNDC1 . . . . . . . . . . . . . . KIF5C KIF5C KIF5C . . . . . . ACVR2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . GTDC1 . . . .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron

-0.041 0.517 0.009 0.021 -0.166 -0.364 -0.097 -0.085 -0.048 0.303 . . -0.302 -0.086 . -0.236 . . 0.034 . -0.015 . 0.478 0.039 0.297 0.187 -0.048 0.132 -0.149 0.544 0.367 0.106 -0.066 1.638 -0.604 0.2 . 0.738 . 0.249 0.203 0.054 0.236 0.458 0.05 . 0.06 -0.192 -0.044 0.05 0.014 0.157 -0.041 . -0.004 -0.244 0.054 -0.129 0.084 0.142 . -0.065 . -0.033 0.083 0.075 0.886 -0.021 0.746 -0.101 0.284 0.14 0.64 . 0.113 0.054 0.019 0.56 0.315 0.31 1.516 0.73 1.014 -0.043

rs786262518 rs792973326 rs787156282 rs791836864 rs792410233 rs788276817 213644 rs7882 rs788940214 rs791138178 . 829277 rs7925 rs789294994 . rs697147015 rs790433291 rs792011147 129718 rs7873 208650 rs7877 rs791935134 rs789856867 rs787791742 rs793766940 rs789380752 rs789744071 . rs787129316 781686 rs7869 rs793696946 rs793734884 rs793647362 913607 rs7906 . 319729 rs7911 . rs791744435 rs707442548 rs790750869 rs791678594 rs791923080 . rs788458313 rs788413974 rs786494723 754345 rs7886 rs790933998 rs790644887 rs790296310 rs790258735 rs787723120 247327 rs7866 . rs788112281 rs786685259 316864 rs7876 rs786431934 rs792965161 rs793591991 rs787161988 rs792479545 rs789287243 458206 rs7897 rs786910854 693513 rs7910 680831 rs7925 . rs792903518 rs787195071 . . 175406 rs7938 rs787384045 rs787757442 873375 rs7893 rs789821232 . . . rs791293089 rs786723364 rs787514427 . rs788038404 rs786247219 693333 rs7918

2 2 2 2 2 2 2 2 2 4 2 3 2 2 3 3 3 2 2 3 2 2 2 2 2 4 2 2 2 3 2 2 2 3 2 2 2 2 2 2 4 2 2 2 3 2 2 2 2 3 2 3 2 2 2 2 2 3 2 2 3 3 2 2 2 2 3 2 3 4 2 2 2 2 4 2 3 2 2 2 3 2 2 2

AT.AT AAAC.GTTT AC.GT AAAC.GTTT AAG.CTT AT.AT AAAAT.ATTTT AC.GT AAC.GTT AC.GT AT.AT AC.GT ACAT.ATGT AAAC.GTTT AC.GT AC.GT AAAC.GTTT AG.CT AAT.ATT AT.AT AAAC.GTTT AG.CT AC.GT AT.AT AAAG.CTTT AAAT.ATTT AC.GT AG.CT AC.GT AAAAT.ATTTT AAG.CTT AC.GT AC.GT AT.AT AAAC.GTTT AAAC.GTTT AG.CT AAC.GTT AC.GT AAAC.GTTT AG.CT AAC.GTT AAC.GTT AC.GT AG.CT AGAT.ATCT AG.CT AAAC.GTTT AAAC.GTTT AAAC.GTTT AT.AT AAT.ATT AT.AT AT.AT AAAT.ATTT AAAAC.GTTTT AG.CT AAAAC.GTTTT AT.AT AC.GT AAAAT.ATTTT AAT.ATT AAAAC.GTTTT AAC.GTT AAC.GTT AAAT.ATTT AAAC.GTTT AAC.GTT AAAT.ATTT AGC.GCT AGC.GCT AGC.GCT AT.AT AAAAC.GTTTT AAC.GTT AAT.ATT AC.GT AC.GT ATC.GAT AAAC.GTTT AAAC.GTTT AAAG.CTTT AAAC.GTTT AAT.ATT

15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15

9096196 9196573 9588167 9628528 9894703 9929113 10004594 10436658 10446699 10735343 10761545 11113986 11238617 11274324 12600292 12710618 12760774 13002516 13014687 13047546 13064361 13223439 13572389 13705298 13753457 13817342 14003157 14397991 14414818 14451713 14915434 15057337 15124184 15313580 15364312 15913072 15924426 16138137 16198155 16217770 16237369 16450428 16489858 16507307 16595245 16619836 16688198 16703889 16770737 16965605 17119360 17161874 17395174 17520820 17567963 17734467 18089572 18206178 18783143 18956024 18969836 18985220 19072232 19089584 19264470 19359558 19385971 19441378 19466235 19941803 19941803 19941803 21315368 21427583 21540971 21692422 21694496 22189143 22344590 22426468 22649228 22699815 22815052 22848562

9096212 9196584 9588190 9628539 9894714 9929125 10004608 10436680 10446714 10735365 10761564 11114002 11238632 11274363 12600306 12710627 12760789 13002547 13014708 13047559 13064385 13223449 13572401 13705309 13753479 13817371 14003168 14398001 14414833 14451732 14915447 15057354 15124198 15313591 15364339 15913091 15924436 16138157 16198167 16217786 16237386 16450443 16489871 16507317 16595261 16619863 16688207 16703909 16770759 16965624 17119370 17161887 17395195 17520829 17567980 17734506 18089581 18206206 18783160 18956037 18969860 18985231 19072260 19089597 19264487 19359580 19385995 19441389 19466256 19941819 19941819 19941819 21315377 21427608 21540984 21692450 21694507 22189152 22344609 22426487 22649245 22699832 22815086 22848575

8.5 3 12 3 4 6.5 3 11.5 5.33333 11.5 10 8.5 4 10 7.5 5 4 16 7.33333 7 6.25 5.5 6.5 6 5.75 7.5 6 5.5 8 4 4.66667 9 7.5 6 7 5 5.5 7 6.5 4.25 9 5.33333 4.66667 5.5 8.5 7 5 5.25 5.75 5 5.5 4.66667 11 5 4.5 8 5 5.8 9 7 5 4 5.8 4.66667 6 5.75 6.25 4 5.5 5.66667 5.66667 5.66667 5 5.2 4.66667 9.66667 6 5 6.66667 5 4.5 4.5 8.75 4.66667

ENSSSCT00000017070 . intron ENSSSCT00000017070 . intron . . intergenic ENSSSCT00000017072 KYNU intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000017081 . intron ENSSSCT00000017081 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000017083 SPOPL intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000017092 R3HDM1 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000017094 ZRANB3 intron ENSSSCT00000017094 ZRANB3 intron ENSSSCT00000017095 RAB3GAP1 intron . . intergenic ENSSSCT00000017096 MAP3K19 intron ENSSSCT00000017097 CCNT2 intron ENSSSCT00000017097 CCNT2 intron ENSSSCT00000017100 . intron ENSSSCT00000036620 . intron ENSSSCT00000034389 . intron . . intergenic ENSSSCT00000031658 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

. 1.308 -0.057 0.069 . 0.019 . 0.092 1.538 . 0.122 -0.125 -0.189 -0.092 . -0.169 -0.182 -0.233 -0.11 0.207 0.138 -0.101 -0.22 0.097 -0.058 0.144 0.072 . -0.009 0.026 -0.029 . -0.153 0.178 0.065 0.113 . . -0.181 0.138 . 0.145 0.459 -0.319 0.077 -0.116 . 0.108 0.156 -0.158 . 0.115 0.062 -0.004 . 0.204 0.077 0.255 0.073 0.232 0.528 . . 0.23 0.204 . 0.494 0.392 -0.099 -0.082 -0.082 -0.082 -0.021 -0.073 -0.098 -0.091 -0.131 0.086 -0.031 0.068 . 0.099 0.321 0.071

. rs788200412 . 163914 rs7862 187505 rs7931 rs790617741 rs793127213 . 486188 rs7928 rs793166489 rs786424310 rs793172882 rs793622745 rs791507954 408014 rs6992 . rs793519326 rs792712312 rs789218785 rs788810728 rs787913386 rs711487972 rs793418767 rs789386808 495666 rs7890 rs792267453 rs790352246 rs792386792 rs788782183 rs787065318 356832 rs7925 rs791310832 361603 rs7929 rs792737168 204587 rs7895 rs787877386 . rs793742344 . rs791817720 957870 rs7922 685449 rs7924 520542 rs7875 628008 rs7933 . 056436 rs7918 . 086328 rs7876 rs793732807 307310 rs7869 rs793674413 rs788521192 rs791049410 rs791190860 rs792425936 579135 rs7896 . rs788316744 rs788412391 rs789947965 339219 rs7905 rs691986805 rs793172458 rs787457884 rs791037470 rs790023183 968349 rs7915 rs787591063 rs793224032 rs789684041 rs789684041 rs789684041 rs786979248 rs793092527 937975 rs7920 . rs786492165 . rs793733994 rs789863994 rs792610614 . rs787300278 rs792225614

2 2 4 2 2 3 2 4 2 2 2 3 2 2 4 3 2 2 2 4 2 3 2 3 2 2 2 2 4 2 2 2 2 2 2 2 2 2 4 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 3 2 3 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 3 2

AT.AT AG.CT AC.GT AAAG.CTTT AATG.CATT AAAG.CTTT AC.GT AC.GT AT.AT AAAAT.ATTTT AT.AT AAAAT.ATTTT AT.AT AAAT.ATTT AC.GT AG.CT AC.GT ACAT.ATGT AT.AT AC.GT ACACCC.GGGTG AAAC.GTTT AAC.GTT AC.GT AGAT.ATCT AG.CT AAATT.AATTT AAAC.GTTT ACAT.ATGT ACAG.CTGT ACAG.CTGT ACAG.CTGT AT.AT AT.AT AT.AT ACC.GGT AAAG.CTTT AT.AT AAAT.ATTT AG.CT AG.CT AAAG.CTTT AGG.CCT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAT.ATT AAAAAC.GTTTTT AAAC.GTTT AC.GT AC.GT AAAT.ATTT AC.GT AT.AT AAT.ATT AGC.GCT AAC.GTT AAAT.ATTT AAAT.ATTT AC.GT ATC.GAT AT.AT AC.GT AC.GT AT.AT AAAC.GTTT AAAC.GTTT AAAAG.CTTTT AC.GT AAAC.GTTT AAAAC.GTTTT AAAC.GTTT AT.AT AAC.GTT AAC.GTT AG.CT AT.AT AAG.CTT AG.CT AAAT.ATTT AT.AT AC.GT AC.GT AAAAT.ATTTT

15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15

22853859 22890843 23018730 23141240 23250661 23271564 23460904 23731154 24340953 24522928 24540570 24623049 24647456 24647858 24710157 24744644 24895452 25095122 25181235 25253547 25464762 25562580 25911971 25944999 26261522 26285265 26351946 26365778 26788373 26804286 26804286 26804286 26810048 26810048 26810048 26936676 27209091 27233535 27686569 28145090 28145090 28230882 28330701 28530885 28539153 28597437 28715045 28739359 28797671 28850198 28850198 28902746 28917033 28918431 28980779 28983598 29233015 29299267 29819983 29838158 29977999 29995151 30004710 30202575 30244464 30987917 31054854 31060959 31073298 31261978 31692702 31778204 31789870 31791280 31799601 32048796 32246906 32262540 32377213 32474928 32501864 32576520 32845492 32875764

22853868 22890856 23018741 23141262 23250676 23271581 23460918 23731164 24340962 24522944 24540579 24623063 24647471 24647880 24710184 24744657 24895463 25095136 25181246 25253558 25464783 25562593 25911986 25945019 26261542 26285278 26351970 26365797 26788388 26804307 26804307 26804307 26810065 26810065 26810065 26936694 27209105 27233545 27686589 28145105 28145105 28230908 28330714 28530908 28539171 28597456 28715065 28739377 28797701 28850208 28850208 28902764 28917053 28918443 28980791 28983611 29233037 29299286 29820002 29838179 29978017 29995162 30004719 30202590 30244475 30987933 31054881 31060978 31073310 31261996 31692724 31778227 31789880 31791297 31799619 32048813 32246918 32262562 32377223 32474949 32501875 32576530 32845508 32875782

5 7 6 5.75 4 4.5 7.5 5.5 5 3.4 5 3 8 5.75 14 7 6 3.75 6 6 3.66667 3.5 5.33333 10.5 5.25 7 5 5 4 5.5 5.5 5.5 9 9 9 6.33333 3.75 5.5 5.25 8 8 6.75 4.66667 6 4.75 5 7 3.16667 7.75 5.5 5.5 4.75 10.5 6.5 4.33333 4.66667 7.66667 5 5 11 6.33333 6 5 8 6 4.25 7 4 6.5 4.75 4.6 6 5.5 6 6.33333 9 6.5 7.66667 5.5 5.5 6 5.5 8.5 3.8

. . . . . . . . . . . ENSSSCT00000031946 ENSSSCT00000031946 ENSSSCT00000031946 ENSSSCT00000031946 . . . . ENSSSCT00000017111 . . . . . . . . . ENSSSCT00000025125 ENSSSCT00000025310 ENSSSCT00000017112 ENSSSCT00000025125 ENSSSCT00000025310 ENSSSCT00000017112 ENSSSCT00000017114 . . . ENSSSCT00000034415 ENSSSCT00000017116 . . ENSSSCT00000017118 ENSSSCT00000017118 . . . ENSSSCT00000030086 ENSSSCT00000022881 ENSSSCT00000030086 ENSSSCT00000017121 . . . . . . . . . . . . . . . . . ENSSSCT00000017126 ENSSSCT00000017126 ENSSSCT00000017126 ENSSSCT00000017126 ENSSSCT00000017126 ENSSSCT00000017126 . . . . . . . . .

. . . . . . . . . . . . . . . . . . . DPP10 . . . . . . . . . . . . . . . CCDC93 . . . MARCO MARCO . . C2orf76 C2orf76 . . . MAP3K2 MAP3K2 MAP3K2 ERCC3 . . . . . . . . . . . . . . . . . CNTNAP5 CNTNAP5 CNTNAP5 CNTNAP5 CNTNAP5 CNTNAP5 . . . . . . . . .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic promoter promoter promoter intron intron intron intron intergenic intergenic intergenic intron intron intergenic intergenic intron intron intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

-0.271 -0.161 . 0.09 -0.104 . -0.22 0.277 0.066 0.025 -0.066 0.198 . . 0.069 -0.12 -0.059 -0.082 . -0.088 . . 0.074 . 0.296 . 0.084 -0.063 0.111 -0.07 -0.07 -0.07 -0.039 -0.039 -0.039 0.041 0.023 . -0.056 0.266 0.266 . -0.253 0.313 0.202 -0.207 0.135 0.216 . -0.027 -0.027 -0.058 . -0.072 -0.188 -0.038 . . . -0.032 0.016 . . -0.257 . -0.285 -0.105 -0.219 . 0.155 -0.2 -0.051 . . -0.291 -0.188 -0.198 -0.192 -0.253 0.012 -0.244 0.965 -0.171 .

. rs712694662 . rs788325089 rs789892012 rs786983271 . rs791871003 rs788059585 rs787779848 rs789408810 rs789946961 . rs788046773 rs792296320 rs790991562 . rs789442542 rs789433787 . rs789887254 102900 rs7866 rs788380040 . rs788168321 . rs789425375 rs787195877 089305 rs7913 962753 rs7875 962753 rs7875 962753 rs7875 551234 rs7882 551234 rs7882 551234 rs7882 rs789820615 . rs786638684 rs786400497 rs789921818 rs789921818 rs792062396 rs793740672 . rs791125899 rs791799615 rs787359478 rs791502899 rs787242923 . . 334504 rs7927 rs792890847 rs792548042 rs793114068 rs709651006 075472 rs7906 594866 rs7877 287617 rs7879 270888 rs7898 rs792009258 rs705197599 rs789239408 . 113731 rs7928 rs790916410 rs793728658 rs789376407 rs787812618 rs786602637 rs792579296 rs787199014 rs789752598 rs692704124 . rs790587798 . rs791287421 rs792528283 679005 rs7884 281946 rs7889 . 519343 rs7873 rs789631890

3 3 2 2 2 2 3 2 3 2 2 2 2 2 2 2 3 2 3 3 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 4 4 2 3 2 2 2 2 2 3 2 2 2 2 2 4 2 2 2 3 3 2 2 2 2 2 2 4 2 2 2 3 3 2 2

AT.AT AAAC.GTTT AT.AT AC.GT AC.GT AAAAT.ATTTT AT.AT AT.AT AAG.CTT AAC.GTT AC.GT ACCC.GGGT AG.CT AG.CT AAAT.ATTT AAC.GTT AG.CT AG.CT AG.CT AG.CT AAAAT.ATTTT AAAC.GTTT AAAAC.GTTTT AAC.GTT AAG.CTT AATG.CATT AG.CT AC.GT AAAC.GTTT AAAAT.ATTTT ACC.GGT AAAC.GTTT AT.AT AAC.GTT AAAC.GTTT AAAAT.ATTTT AAAC.GTTT AAAG.CTTT AT.AT AC.GT ACAC.GTGT AC.GT AAAAT.ATTTT AC.GT AC.GT AAG.CTT AAC.GTT AT.AT AAAAG.CTTTT AT.AT AGAT.ATCT ACAT.ATGT AC.GT AG.CT AT.AT AAT.ATT AT.AT AC.GT AC.GT AT.AT ATC.GAT AT.AT AT.AT AC.GT AC.GT AT.AT AT.AT AGG.CCT AG.CT AC.GT AACAC.GTGTT AAAG.CTTT AAC.GTT AAC.GTT AAC.GTT AC.GT AAC.GTT AC.GT AAAT.ATTT AG.CT AAC.GTT AC.GT AAT.ATT AAAT.ATTT

15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15

32938036 33061663 33081552 33196554 33398421 33521992 33528714 33588829 33594565 33600967 33638937 34265011 34655965 34723875 34750350 34985711 35040051 35040051 35040051 35040051 35276732 35434600 35459594 35534571 35541628 35627405 35767373 35955958 36104187 36128622 36186107 36187265 36262363 36504033 36585619 36595568 36700160 36800772 36925683 37435235 37531302 37569972 37768573 38069662 38191070 38683067 39273023 39298552 39391651 39425276 39699295 40123336 40147194 40159987 40208836 40379790 40415630 40613189 40642590 40999136 41065086 41069887 41076224 41156904 41219322 41255147 41531256 41749311 41951219 42137545 42268096 42689429 42723940 42723940 43316350 43324537 43947562 43980139 44386769 44514749 44534727 44704322 44989275 44994312

32938054 33061681 33081564 33196568 33398435 33522012 33528724 33588838 33594585 33600983 33638952 34265022 34655974 34723893 34750370 34985728 35040065 35040065 35040065 35040065 35276758 35434623 35459614 35534583 35541642 35627433 35767387 35955970 36104211 36128642 36186120 36187283 36262372 36504046 36585652 36595582 36700185 36800785 36925697 37435245 37531330 37569986 37768595 38069674 38191117 38683082 39273036 39298562 39391675 39425289 39699312 40123355 40147204 40160001 40208851 40379803 40415640 40613214 40642601 40999145 41065104 41069900 41076240 41156923 41219332 41255160 41531267 41749324 41951231 42137554 42268114 42689452 42723951 42723951 43316374 43324546 43947575 43980148 44386792 44514764 44534756 44704333 44989292 44994324

9.5 4.75 6.5 7.5 7.5 4.2 5.5 5 7 5.66667 8 3 5 9.5 5.25 6 7.5 7.5 7.5 7.5 5.4 6 4.2 4.33333 5 7.25 7.5 6.5 6.25 4.2 4.66667 4.75 5 4.66667 8.5 3 6.5 3.5 7.5 5.5 7.25 7.5 4.6 6.5 24 5.33333 4.66667 5.5 5 7 4.5 5 5.5 7.5 8 4.66667 5.5 13 6 5 6.33333 7 8.5 10 5.5 7 6 4.66667 6.5 5 3.8 6 4 4 8.33333 5 4.66667 5 6 8 10 6 6 3.25

. . . . . . . . . . . . ENSSSCT00000017129 . ENSSSCT00000024092 . ENSSSCT00000033491 ENSSSCT00000017132 ENSSSCT00000033811 ENSSSCT00000033192 ENSSSCT00000017133 ENSSSCT00000023874 ENSSSCT00000023874 . . . . . . ENSSSCT00000017141 . . . ENSSSCT00000025582 ENSSSCT00000027415 ENSSSCT00000027415 . . . . . . ENSSSCT00000027260 ENSSSCT00000017147 . . ENSSSCT00000027445 ENSSSCT00000027445 ENSSSCT00000017148 ENSSSCT00000017148 . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000017154 ENSSSCT00000017154 ENSSSCT00000017155 . . ENSSSCT00000031639 . ENSSSCT00000017167 . . . . .

. . . . . . . . . . . . TSN . . . TFCP2L1 TFCP2L1 TFCP2L1 TFCP2L1 GLI2 . . . . . . . . . . . . . . . . . . . . . CLN8 . . . . . CSMD1 CSMD1 . . . . . . . . . . . . . . . . . . . . . ANGPT2 ANGPT2 MCPH1 . . GPM6A . . . . . . .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intron intergenic intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic promoter promoter intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intron intergenic intron intergenic intergenic intergenic intergenic intergenic

. 0.33 . -0.221 -0.145 . -0.152 . -0.013 -0.186 0.004 -0.151 -0.344 . . . -0.009 -0.009 -0.009 -0.009 -0.143 . -0.156 -0.276 -0.124 -0.283 0.197 0.117 0.381 -0.283 -0.054 0.159 . 0.126 . . . . 0.199 -0.141 . -0.1 . -0.085 -0.342 . -0.028 -0.193 -0.05 -0.491 -0.667 . -0.183 . 0.798 -0.219 -0.324 -0.063 0.028 -0.228 -0.309 -0.664 -0.174 -0.283 -0.195 -0.195 -0.221 -0.122 -0.915 . . -0.514 -0.102 -0.102 . 0.292 . . -0.046 . 0.235 -0.015 . .

rs791873119 rs786707879 328966 rs7901 rs710349359 . rs790147072 147509 rs7938 653008 rs7892 976656 rs7882 727670 rs7905 rs788696658 rs789193614 . . . rs789497981 310178 rs7937 310178 rs7937 310178 rs7937 310178 rs7937 688237 rs7925 rs786303132 248054 rs7889 rs793312464 526130 rs7903 rs788004041 rs790729071 . rs788678908 rs791953879 265959 rs7930 242946 rs7876 179010 rs7895 rs791030721 rs698131914 rs788215203 550042 rs7904 rs695180008 404464 rs7875 . rs792825424 683858 rs7913 rs789223789 rs792367347 271685 rs7927 107144 rs7880 rs792333727 rs791391460 . 446036 rs7871 081747 rs7895 517965 rs7921 rs789835015 245674 rs7932 . rs793033774 477111 rs7868 . rs694550412 rs793692307 rs788961115 rs788759025 rs790995808 rs793518350 . rs787125306 986251 rs7933 906130 rs7876 . 754307 rs7883 rs793555802 rs790353193 . . 416613 rs7912 . . . . . 182480 rs7919 rs788177221 rs791319922 rs789801838

2 2 3 2 2 2 2 2 2 2 2 2 2 5 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 3 4 2 3 2 2 2 3 2 3 2 2 3 2 3 4 3 2 4 2 2 4 4 2 3 4 2 2 4 2 2 2 4 4 2 2 2 3 2 2 4 2 2 2

AC.GT AT.AT ACAG.CTGT AAAC.GTTT AT.AT AC.GT AT.AT AT.AT AAC.GTT AC.GT AAC.GTT AAAC.GTTT AG.CT AT.AT AAAC.GTTT AC.GT AAC.GTT AAAAC.GTTTT AT.AT AC.GT AG.CT AAAG.CTTT AAG.CTT AAAC.GTTT AG.CT AT.AT AAT.ATT AAAC.GTTT AAAC.GTTT AT.AT AC.GT AAAT.ATTT AC.GT AAAAT.ATTTT AC.GT ACAT.ATGT ACAT.ATGT ACAT.ATGT AAG.CTT AAAT.ATTT AG.CT AAT.ATT AAG.CTT AC.GT AT.AT AAAC.GTTT AAAC.GTTT AC.GT AAAT.ATTT AAAAG.CTTTT AC.GT AT.AT AGC.GCT AAAAC.GTTTT AAC.GTT AAAC.GTTT AC.GT AC.GT AC.GT AC.GT AC.GT AGC.GCT AAAAC.GTTTT AC.GT AAAC.GTTT AAAAC.GTTTT AAAT.ATTT AAAAG.CTTTT AAAAG.CTTTT AAAAG.CTTTT AAAC.GTTT AAT.ATT AT.AT AAAG.CTTT AAAAAC.GTTTTT AAC.GTT AACAC.GTGTT AC.GT AAAT.ATTT AAAAC.GTTTT AAAC.GTTT AG.CT AG.CT AAAT.ATTT

15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15

46075247 46319525 46455628 46506859 46513735 46540338 46621041 46646112 46905638 47336824 47453601 47681517 47739075 47787898 48745815 48811828 48825234 48844093 48888342 49180908 49305928 49342991 49680737 49680817 49749522 50167170 50254962 50277880 50343903 50513112 50591680 50607098 50660812 50817775 50834695 50937601 50937601 50937601 51002259 51067510 51124577 51148290 51247454 51348773 51398378 51525206 51534993 51571826 51621066 51646222 51679030 51694104 51698489 51742848 51909005 51955584 52210847 52210847 52210847 52434242 52442644 52518116 53067502 53677209 53700541 53767361 54136895 54412472 54412472 54412472 54503105 54513547 54956145 54992735 55165684 55780792 55833581 56162493 56349786 56563329 56564119 56668824 56814293 56860666

46075262 46319536 46455649 46506878 46513745 46540347 46621056 46646129 46905651 47336836 47453613 47681535 47739103 47787917 48745828 48811837 48825247 48844115 48888356 49180917 49305950 49343020 49680751 49680839 49749538 50167182 50254973 50277896 50343923 50513130 50591705 50607118 50660825 50817801 50834705 50937619 50937619 50937619 51002278 51067528 51124597 51148312 51247467 51348785 51398391 51525226 51535013 51571845 51621087 51646244 51679042 51694113 51698501 51742871 51909026 51955598 52210859 52210859 52210859 52434253 52442654 52518131 53067522 53677219 53700561 53767376 54136915 54412500 54412500 54412500 54503123 54513563 54956156 54992752 55165713 55780808 55833598 56162506 56349800 56563353 56564133 56668840 56814311 56860689

8 6 5.5 5 5.5 5 8 9 4.66667 6.5 4.33333 4.75 14.5 10 3.5 5 4.66667 4.6 7.5 5 11.5 7.5 5 5.75 8.5 6.5 4 4.25 5.25 9.5 13 5.25 7 5.4 5.5 4.75 4.75 4.75 6.66667 4.75 10.5 7.66667 4.66667 6.5 7 5.25 5.25 10 5.5 4.6 6.5 5 4.33333 4.8 7.33333 3.75 6.5 6.5 6.5 6 5.5 5.33333 4.2 5.5 5.25 3.2 5.25 5.8 5.8 5.8 4.75 5.66667 6 4.5 5 5.66667 3.6 7 3.75 5 3.75 8.5 9.5 6

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000017174 . intron . . intergenic . . intergenic ENSSSCT00000032149 . intron . . intergenic ENSSSCT00000022975 TENM3 intron ENSSSCT00000017175 TENM3 intron ENSSSCT00000026310 TENM3 intron . . intergenic ENSSSCT00000017176 DCTD intron . . intergenic . . intergenic ENSSSCT00000028500 WWC2 intron ENSSSCT00000028500 WWC2 intron ENSSSCT00000028500 WWC2 intron . . intergenic ENSSSCT00000025252 ING2 intron . . intergenic ENSSSCT00000017178 TRAPPC11 intron ENSSSCT00000017178 TRAPPC11 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000017181 STOX2 3'utr . . intergenic ENSSSCT00000035483 IRF2 intron ENSSSCT00000032886 IRF2 intron ENSSSCT00000017183 IRF2 intron ENSSSCT00000017188 . intron ENSSSCT00000017188 . intron ENSSSCT00000017189 . intron . . intergenic . . intergenic . . intergenic ENSSSCT00000017210 CYP4V2 intron . . intergenic ENSSSCT00000025294 . intron ENSSSCT00000017214 . intron ENSSSCT00000026211 . intron ENSSSCT00000017215 ADAM32 intron ENSSSCT00000017215 ADAM32 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

-0.028 -0.273 -0.313 . . -0.022 0.045 -0.002 0.069 . . -0.255 -0.035 -0.142 -0.392 0.214 0.088 0.45 -0.088 1.381 0.109 0.054 . . -0.124 -0.171 -0.041 -0.106 0.295 0.028 0.321 0.198 0.863 -0.004 0.066 0.163 0.163 0.163 . -0.368 . 0.41 . 0.12 0 0.06 0.291 0.139 0.177 0.021 -0.093 0.309 -0.128 0.071 3.499 -0.148 -0.184 -0.184 -0.184 0.204 -0.263 -0.053 -0.131 0.009 0.065 . . . . . . . -0.105 0.069 -0.116 0.383 -0.419 1.102 0.026 0.158 0.086 -0.057 0.1 -0.085

209062 rs7909 897195 rs7873 rs792690199 . rs787564632 . rs788313054 rs787969229 . . rs789415994 rs708008271 759423 rs7879 . rs791023537 rs786722007 406781 rs7885 rs790715284 . rs788081611 . 028109 rs7870 235071 rs7868 rs791498794 rs790090455 rs790540384 rs786737288 531453 rs7903 158651 rs7899 347295 rs7916 rs786777276 774165 rs7878 rs791672542 rs787383502 rs790371129 119700 rs7918 119700 rs7918 119700 rs7918 rs790360611 . rs791287402 rs787691304 rs788874186 rs790751410 251409 rs7937 rs787441060 rs792390087 rs790779597 rs792305290 rs788521723 rs793710507 rs793064055 rs790533610 rs787186952 316552 rs7907 423905 rs7917 rs787649232 rs787649232 rs787649232 rs793451454 . . rs789298160 rs787757306 rs705411007 rs787452369 rs791955098 rs705867287 rs705867287 rs705867287 rs790344781 . rs789183319 rs789076421 rs793825362 . rs790097439 . 264956 rs7872 . 833640 rs7866 rs790479984 . .

2 2 2 2 2 3 3 2 2 3 2 2 2 2 2 4 2 2 2 2 2 2 2 2 4 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 3 2 3 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 4 3 2 2 2 2 2 2 2 2 2 2 4 2 2 4 2 4 2 3 2 3 4 2

AAC.GTT AAC.GTT ACAT.ATGT AAAC.GTTT AAAT.ATTT AGGG.CCCT AAT.ATT AAAC.GTTT AAAC.GTTT AG.CT AAAAT.ATTTT AG.CT AAAT.ATTT AAAT.ATTT AAAAAT.ATTTTT AAAG.CTTT AAAAC.GTTTT AAAC.GTTT AT.AT AAAAC.GTTTT AC.GT AG.CT AC.GT AAAT.ATTT AT.AT AT.AT AAAAC.GTTTT AG.CT AAAC.GTTT AT.AT AT.AT AC.GT AAC.GTT AAC.GTT AT.AT AAAC.GTTT AAAT.ATTT AC.GT AAAC.GTTT AAC.GTT AGGG.CCCT AGGC.GCCT AAGT.ACTT AAAAT.ATTTT AC.GT AAAT.ATTT AAAC.GTTT AAAAT.ATTTT AAAAG.CTTTT AAAT.ATTT AC.GT AAG.CTT AAAGGG.CCCTT AATG.CATT AAAC.GTTT AAAC.GTTT AC.GT AT.AT AT.AT AT.AT AAAAG.CTTTT AAAAG.CTTTT AAAAG.CTTTT AG.CT AG.CT AG.CT AAAC.GTTT AAAC.GTTT AC.GT AC.GT AAAT.ATTT AAAT.ATTT AAAATC.GATTTT AT.AT AT.AT AT.AT AT.AT AAAAG.CTTTT AAAT.ATTT AAT.ATT AAC.GTT AT.AT AC.GT AG.CT

15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15

56916180 56998377 57492002 57639011 57711042 57926397 57977564 58123420 58186064 58468578 58939710 59242670 59458978 59473627 59502295 59821978 59877969 59913688 60303081 60959984 61308209 61665171 61896076 62188799 62255209 62255209 62350130 62443862 62602793 62676209 62971065 63003143 63066186 63093482 63102747 63143378 63298328 63673913 63703707 63790396 64030345 64242795 64287295 64340202 64547828 64716143 64861066 64884510 65114028 65313683 65472057 65700946 65857161 65984801 66418170 66456762 66633760 66733922 66733922 66733922 66832833 66832833 66832833 66874335 66874335 66874335 67542820 68091045 68182658 68598419 68881771 69299908 69425439 69659850 69699838 69886069 70383655 70618514 70955501 70993664 71027604 71292172 72235206 72379599

56916192 56998397 57492014 57639030 57711061 57926408 57977593 58123443 58186079 58468592 58939732 59242700 59458995 59473646 59502315 59821992 59877985 59913714 60303090 60960000 61308236 61665182 61896087 62188814 62255227 62255227 62350155 62443878 62602815 62676222 62971078 63003153 63066200 63093495 63102761 63143410 63298348 63673922 63703725 63790408 64030359 64242809 64287311 64340228 64547854 64716160 64861092 64884531 65114051 65313697 65472071 65700957 65857184 65984831 66418194 66456778 66633783 66733936 66733936 66733936 66832865 66832865 66832865 66874347 66874347 66874347 67542838 68091067 68182683 68598454 68881783 69299940 69425466 69659861 69699847 69886079 70383664 70618534 70955513 70993686 71027621 71292181 72235217 72379613

4.33333 7 3.25 5 5 3 10 6 4 7.5 4.6 15.5 4.5 5 3.5 3.75 3.4 6.75 5 3.4 14 6 6 4 9.5 9.5 5.2 8.5 5.75 7 7 5.5 5 4.66667 7.5 8.25 5.25 5 4.75 4.33333 3.75 3.75 4.25 5.4 13.5 4.5 6.75 4.4 4.8 3.75 7.5 4 4 7.75 6.25 4.25 12 7.5 7.5 7.5 6.6 6.6 6.6 6.5 6.5 6.5 4.75 5.75 13 18 3.25 8.25 4.66667 6 5 5.5 5 4.2 3.25 7.66667 6 5 6 7.5

. . intergenic . . intergenic ENSSSCT00000017238 UNC5D intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000017242 RNF122 promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000017253 GTF2E2 intron . . intergenic ENSSSCT00000017255 . intron ENSSSCT00000020631 7SK promoter . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000017259 TNKS intron ENSSSCT00000017259 TNKS intron ENSSSCT00000017259 TNKS intron ENSSSCT00000017259 TNKS intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000017261 . intron ENSSSCT00000017263 OCA2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000017277 FMNL2 intron ENSSSCT00000028547 FMNL2 intron ENSSSCT00000023011 FMNL2 intron ENSSSCT00000017277 FMNL2 intron ENSSSCT00000028547 FMNL2 intron ENSSSCT00000023011 FMNL2 intron ENSSSCT00000017277 FMNL2 intron ENSSSCT00000028547 FMNL2 intron ENSSSCT00000023011 FMNL2 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000024665 . intron . . intergenic ENSSSCT00000017281 KCNJ3 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000030069 GALNT5 intron . . intergenic . . intergenic

-0.015 -0.006 -0.116 -0.329 0.41 -0.151 0.482 -0.263 -0.113 -0.247 0.107 -0.04 . 0.525 . -0.09 0.784 0.003 . 0.132 0.236 0.14 0.161 -0.295 . . . 0.902 0.362 0.027 0.173 0.145 0.271 0.148 0.007 . -0.331 . -0.061 3.05 0.089 . . -0.207 -0.073 . 0.119 0.064 . . . . 0.04 . -0.2 -0.401 0.393 0.063 0.063 0.063 -0.336 -0.336 -0.336 0.018 0.018 0.018 0.164 . 0.048 -0.066 -0.16 0.165 -0.052 0.029 0.039 -0.003 -0.011 0.426 0.165 0.179 0.251 -0.049 0.109 0.296

rs791207099 rs793437287 . 351688 rs7877 117028 rs7924 rs786831642 rs788922088 rs787668439 rs793370232 rs792062571 rs792627637 . 804173 rs7886 rs791691049 rs793886459 rs705862048 901294 rs7882 rs788502728 rs788891968 002462 rs7888 586778 rs7863 rs786963312 882065 rs7870 018884 rs7888 rs792580461 rs792580461 180875 rs7919 . rs789197251 rs792910245 380939 rs7875 . rs787680408 rs788724942 rs788787126 . rs789503551 rs786292938 rs791778627 rs788533780 rs786898531 . 963964 rs7879 087618 rs7926 rs792864802 rs790652479 rs789036949 rs793802639 rs788037107 128435 rs7882 806051 rs7920 rs787772256 868449 rs7924 rs791615641 rs792190163 rs790952919 rs787836048 . . . rs792895920 rs792895920 rs792895920 . . . rs789077666 rs793405246 365207 rs7873 rs792974938 792336 rs7878 rs790492690 rs791624620 rs786500150 rs786429154 rs790211287 . rs789196978 rs787115166 rs792545337 107670 rs7901 rs791284862 rs787975119 .

4 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 3 2 4 2 3 2 2 2 2 2 2 4 2 2 2 3 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 3 3 2 2 2 3 2 2 2 2 2 4 4 2 2 2 2 4 2 4

AAAC.GTTT AAAC.GTTT AAAAT.ATTTT AT.AT AC.GT AAAC.GTTT AAAC.GTTT AT.AT AT.AT AT.AT AT.AT AT.AT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAC.GTT AAC.GTT AT.AT AT.AT AG.CT AG.CT AAAAG.CTTTT AAAAG.CTTTT AAAC.GTTT AC.GT ATCC.GGAT AAC.GTT AC.GT AAAC.GTTT AT.AT AC.GT AT.AT AAC.GTT AC.GT AAAG.CTTT AAAG.CTTT AAAG.CTTT AAAC.GTTT AAAT.ATTT AAAT.ATTT AT.AT AC.GT AAAT.ATTT AAAT.ATTT AC.GT AGAT.ATCT AT.AT AAAG.CTTT AT.AT AC.GT AAAAAC.GTTTTT AC.GT AG.CT AAAT.ATTT AT.AT AAAC.GTTT AAAG.CTTT AG.CT AAAT.ATTT AATG.CATT AT.AT AC.GT AAAT.ATTT AC.GT AAAC.GTTT AAAT.ATTT ACAT.ATGT AT.AT AT.AT AAAAC.GTTTT AAAC.GTTT AATC.GATT AAAC.GTTT AC.GT ATCC.GGAT AAAT.ATTT AAAT.ATTT AC.GT AC.GT AC.GT AAAC.GTTT AAAAAC.GTTTTT

15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15

72458615 72603682 72746081 72995134 73115258 73522615 73522615 73524535 73524535 73548841 73548841 73793986 73842117 73933343 73933343 73977874 73977874 73996718 73996718 74187338 74187338 74187754 74187754 74225024 74225024 74362371 74402823 74483032 74601236 74797072 75142603 75205413 75325781 75544741 75632980 75879495 76094741 76094741 76094741 76243187 76370770 76370770 76401215 76455829 76906922 76917099 77035172 77061375 77137064 77696008 77861867 78005735 78245393 78269224 78288429 78293773 78488708 79963856 80265602 80407277 80519837 80753242 80882873 81231015 82314956 82441259 82470634 82806875 82879341 82934548 83044400 83258950 83380323 83431914 83477699 83598049 84488147 84551181 84551181 84900144 85017895 85017895 85076661 85178218

72458634 72603700 72746105 72995149 73115285 73522642 73522642 73524544 73524544 73548853 73548853 73793998 73842145 73933364 73933364 73977890 73977890 73996736 73996736 74187355 74187355 74187770 74187770 74225043 74225043 74362389 74402835 74483059 74601258 74797081 75142634 75205425 75325807 75544756 75632991 75879508 76094778 76094778 76094778 76243209 76370792 76370792 76401225 76455845 76906933 76917112 77035199 77061400 77137077 77696029 77861877 78005758 78245411 78269234 78288438 78293798 78488730 79963892 80265632 80407286 80519859 80753270 80882883 81231028 82314975 82441271 82470654 82806892 82879378 82934559 83044411 83258972 83380336 83431938 83477722 83598059 84488170 84551205 84551205 84900167 85017914 85017914 85076683 85178245

5 4.75 5 8 14 7 7 5 5 6.5 6.5 6.5 7.25 5.5 5.5 4.25 4.25 6.33333 6.33333 9 9 8.5 8.5 4 4 4.75 6.5 7 7.66667 5 8 6.5 13.5 8 4 7 9.5 9.5 9.5 5.75 5.75 5.75 5.5 8.5 3 3.5 14 6.5 7 5.5 5.5 12 3.16667 5.5 5 6.5 11.5 9.25 7.75 5 5.75 7.25 5.5 7 5 6.5 5.25 4.5 9.5 6 6 4.6 3.5 6.25 6 5.5 6 6.25 6.25 12 10 10 5.75 4.66667

ENSSSCT00000017287 . ENSSSCT00000017290 . . ENSSSCT00000017294 ENSSSCT00000024565 ENSSSCT00000017294 ENSSSCT00000024565 ENSSSCT00000017294 ENSSSCT00000024565 . . ENSSSCT00000031773 ENSSSCT00000017295 ENSSSCT00000032142 ENSSSCT00000034209 ENSSSCT00000032142 ENSSSCT00000035518 ENSSSCT00000017297 ENSSSCT00000017298 ENSSSCT00000017297 ENSSSCT00000017298 ENSSSCT00000017297 ENSSSCT00000017298 . . ENSSSCT00000017300 . . . . . . . . ENSSSCT00000027600 ENSSSCT00000023989 ENSSSCT00000017305 . ENSSSCT00000017308 ENSSSCT00000036390 . ENSSSCT00000017310 . . . . . . . . . . . . . ENSSSCT00000029568 . ENSSSCT00000017318 . . . . . . . . . . . . . ENSSSCT00000030087 ENSSSCT00000030087 . ENSSSCT00000017341 ENSSSCT00000017343 ENSSSCT00000017342 . ENSSSCT00000025574 ENSSSCT00000017349 ENSSSCT00000017350 .

. . . . . BAZ2B BAZ2B BAZ2B BAZ2B BAZ2B BAZ2B . . 7-Mar 7-Mar LY75 LY75 LY75 LY75 PLA2R1 . PLA2R1 . PLA2R1 . . . RBMS1 . . . . . . . . SLC4A10 SLC4A10 SLC4A10 . FAP FAP . IFIH1 . . . . . . . . . . . . . SLC38A11 . SCN2A . . . . . . . . . . . . . . . . G6PC2 ABCB11 ABCB11 . FASTKD1 FASTKD1 PPIG .

intron intergenic intron intergenic intergenic intron intron intron intron intron intron intergenic intergenic intron intron intron intron intron intron intron intron intron intron intron intron intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intron intron intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intron intron intron intergenic intron intron intron intergenic

0.208 0.129 . -0.505 0.062 0.348 0.348 0.393 0.393 0.154 0.154 . . 1.29 1.29 0.283 0.283 0.374 0.374 0.202 0.202 1.185 1.185 . . 0.212 0.232 0.186 0.24 -0.017 0.056 0.395 1.392 0.292 0.592 0.297 0.196 0.196 0.196 0.262 1.153 1.153 0.122 1.335 0.088 0.085 -0.075 -0.121 0.078 0.123 0.619 0.759 3.479 0.127 . 0.21 -0.051 . 0.006 -0.15 -0.047 0.09 1.661 . . -0.096 . 0.022 0.167 0.129 . 0.181 . -0.241 -0.092 -0.107 0.139 0.232 0.232 . 0.936 0.936 0.102 .

. 854692 rs7925 rs790942855 . rs789963009 rs792748417 rs792748417 rs788391162 rs788391162 rs789836453 rs789836453 150977 rs7862 . 697980 rs7904 697980 rs7904 rs787108027 rs787108027 rs789953761 rs789953761 . . . . rs791069609 rs791069609 rs790596380 . rs791872527 719290 rs7910 rs790815387 rs789670136 . rs793032950 rs788671663 rs788692030 rs789048407 . . . 199002 rs7899 869708 rs7888 869708 rs7888 rs791991103 . rs787774824 rs788118856 rs788829849 480987 rs7883 rs790479520 rs787452153 . . 265482 rs7927 . . rs789811758 rs786710084 132216 rs7872 rs789941774 rs792919306 rs789385303 rs793039656 802423 rs7912 rs788150270 rs787912263 rs793867984 rs786743650 rs787295052 rs786975114 rs791708809 rs788922979 rs786816449 rs694912653 596061 rs7902 356906 rs7883 . rs793016709 rs789979812 rs789979812 . . . 112844 rs7873 rs791770524

3 2 2 2 2 2 2 2 2 3 3 2 2 2 2 2 2 2 2 3 3 3 3 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 4 2 4 2 2 2 2 2 2 2 2 2 3 2 2 3 2 2 2 2 2 3 2 2 2 2 2 3 2 2 2 2 2 2 2 2

AT.AT AAAC.GTTT AAC.GTT AC.GT AAAAAC.GTTTTT AATAT.ATATT AT.AT AAAAG.CTTTT AAG.CTT AAC.GTT AAAACC.GGTTTT AG.CT AAAC.GTTT AAAC.GTTT AAC.GTT AAAAAC.GTTTTT AT.AT AT.AT AG.CT AC.GT AAAAG.CTTTT AC.GT AT.AT AAAC.GTTT AC.GT AAAAC.GTTTT AT.AT AAAC.GTTT AAAAC.GTTTT AAAT.ATTT AAAT.ATTT AAAC.GTTT AAG.CTT AAAT.ATTT AT.AT AC.GT AAAC.GTTT AT.AT AAACC.GGTTT AC.GT AAAC.GTTT ATC.GAT AT.AT AC.GT AAAT.ATTT AC.GT AT.AT AT.AT AAAAC.GTTTT AGC.GCT AGG.CCT AAAAC.GTTTT AAAC.GTTT ACAG.CTGT AAAC.GTTT AC.GT AG.CT AATC.GATT AAC.GTT ATC.GAT AC.GT AAAG.CTTT AG.CT AAC.GTT AAAC.GTTT AAAT.ATTT AT.AT AC.GT AATG.CATT AC.GT AAAC.GTTT AT.AT AGC.GCT ACCT.AGGT AG.CT AC.GT AT.AT AAAT.ATTT ACCC.GGGT AAAAAG.CTTTTT AC.GT AAAT.ATTT AAAC.GTTT AATT.AATT

15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15

85479990 85498638 85542144 85639400 85793873 86281241 86429901 86460496 86509591 86525961 86574335 86886498 86952512 86952512 87146459 87164452 87368958 87368958 87649329 87757170 87966213 88130192 88132156 88169846 88250310 88287592 88307752 88472783 88518928 88537271 88554502 88573908 88602245 88620245 88786357 89301581 89415419 89739679 89826586 89887324 89909911 89983432 90130124 90133087 90289749 90323927 90354287 90457134 90745129 90807655 91471810 91483636 91520321 91639167 91750972 91963515 92019559 92072097 92190366 92225740 92274846 92344650 92901608 93329415 93498834 93571469 93592633 93649081 93678184 93747239 94160431 94240907 94718562 95047512 95246966 96072767 96479947 96505476 96818994 96996469 97018570 97021034 97227849 97392411

85479999 85498656 85542155 85639425 85793900 86281255 86429912 86460517 86509604 86525974 86574360 86886508 86952530 86952530 87146475 87164473 87368971 87368971 87649340 87757181 87966239 88130208 88132166 88169865 88250342 88287605 88307762 88472812 88518963 88537289 88554515 88573929 88602269 88620261 88786367 89301593 89415455 89739689 89826611 89887338 89909931 89983451 90130134 90133099 90289767 90323941 90354299 90457145 90745147 90807674 91471829 91483662 91520337 91639189 91750990 91963525 92019569 92072110 92190384 92225753 92274860 92344668 92901623 93329434 93498863 93571485 93592656 93649092 93678210 93747254 94160445 94240917 94718579 95047540 95246989 96072785 96479959 96505494 96819008 96996488 97018595 97021056 97227865 97392428

5 4.75 4 13 4.66667 3 6 4.4 4.66667 4.66667 4.33333 5.5 4.75 4.75 5.66667 3.66667 7 7 6 6 5.4 8.5 5.5 5 16.5 2.8 5.5 7.5 7.2 4.75 3.5 5.5 8.33333 4.25 5.5 6.5 9.25 5.5 5.2 7.5 5.25 6.66667 5.5 6.5 4.75 7.5 6.5 6 3.8 6.66667 6.66667 5.4 4.25 5.75 4.75 5.5 5.5 3.5 6.33333 4.66667 7.5 4.75 8 6.66667 7.5 4.25 12 6 6.75 8 3.75 5.5 6 7.25 12 9.5 6.5 4.75 3.75 3.33333 13 5.75 4.25 4.5

ENSSSCT00000017356 ENSSSCT00000017356 . . . . . . ENSSSCT00000017360 . ENSSSCT00000017361 ENSSSCT00000017362 ENSSSCT00000023821 ENSSSCT00000017364 . . ENSSSCT00000017366 ENSSSCT00000022813 ENSSSCT00000017371 . . ENSSSCT00000031710 ENSSSCT00000031710 ENSSSCT00000031710 ENSSSCT00000031710 . . . ENSSSCT00000017378 ENSSSCT00000017378 ENSSSCT00000017378 ENSSSCT00000017378 ENSSSCT00000017378 ENSSSCT00000017378 . . ENSSSCT00000017382 . ENSSSCT00000028507 . . . . . ENSSSCT00000017391 . . . . . . . . . . . . . . . . . ENSSSCT00000017415 ENSSSCT00000017417 . ENSSSCT00000027373 ENSSSCT00000027373 . ENSSSCT00000017418 . ENSSSCT00000017424 . . . . . . . . . ENSSSCT00000024180 ENSSSCT00000024180 ENSSSCT00000027867 ENSSSCT00000027867

. . . . . . . . GORASP2 . TLK1 METTL8 DCAF17 DCAF17 . . SLC25A12 SLC25A12 DLX2 . . . . . . . . . . . . . . . . . OLA1 . WIPF1 . . . . . ATF2 . . . . . . . . . . . . . . . . . PDE11A RBM45 . OSBPL6 OSBPL6 . PRKRA . CCDC141 . . . . . . . . . PDE1A PDE1A . .

intron intron intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intron intron intron intron intergenic intergenic intron intron promoter intergenic intergenic intron intron intron intron intergenic intergenic intergenic intron intron intron intron intron intron intergenic intergenic intron intergenic intron intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron promoter intergenic intron intron intergenic intron intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron

0.187 0.32 0.271 0.206 . 0.198 . 0.225 -0.17 . 0.263 0.308 . . 0.111 0.194 0.315 0.315 0.172 . . -0.125 0.048 0.746 0.186 0.048 . . 0.437 . . 0.158 0.483 0.269 0.175 0.273 0.25 0.568 . . 0.278 0.182 . -0.01 0.251 0.132 . 0.061 -0.089 0.024 . 0.742 -0.032 0.262 -0.041 0.025 0.229 0.271 0.284 0.239 0.204 . 0.236 0.079 0.202 0.167 0.237 . 0.011 0.202 0.547 . 0 0.059 0.103 -0.014 -0.124 0.056 -0.049 -0.05 0.087 3.665 0.085 0.085

254225 rs7910 rs786362079 rs788611896 140915 rs7930 rs790913809 rs792401315 rs788273603 128503 rs7874 rs789299780 rs788656375 rs788828621 . rs792236291 rs792236291 rs789802622 rs786450414 rs790816980 rs790816980 rs793282223 . rs787853369 463962 rs7863 rs787175452 797653 rs7872 409157 rs7932 rs788787474 810310 rs7921 472374 rs7905 098064 rs7926 rs787668762 rs792615612 rs788506805 . rs788964221 rs792295205 . rs790473872 rs790630708 rs789351396 rs792710524 rs791898113 . 436367 rs7935 001178 rs7893 rs788298288 405688 rs7919 080305 rs7870 rs699786243 342070 rs7931 rs788109430 891260 rs7878 186290 rs7929 rs789840246 900036 rs7024 646716 rs7864 . . rs792746758 rs789882563 rs789738242 rs791845995 rs786562538 rs788903860 117624 rs6904 rs787774825 397760 rs7892 358505 rs7886 rs786400176 647120 rs7919 . rs790311326 . 044752 rs7873 . rs791689812 rs787447913 rs786700754 631364 rs7925 . 344344 rs7870 . rs786510926 rs792953840 rs792139599

2 2 2 4 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 3 2 3 2 3 2 2 2 2 2 4 2 3 2 2 2 2 3 2 2 2 2 2 4 2 2 2 2 3 2 2 2 4 2 2 2 2 4 2 2 2

AAATT.AATTT AC.GT AAAC.GTTT AAATT.AATTT AG.CT AAAC.GTTT AAC.GTT AAAC.GTTT AATT.AATT AC.GT AC.GT AC.GT AAAAC.GTTTT AAAAT.ATTTT AAAC.GTTT AC.GT AATT.AATT AC.GT AAAG.CTTT AAAC.GTTT AT.AT AC.GT AAT.ATT AT.AT AC.GT AC.GT AC.GT AAAAT.ATTTT AAAC.GTTT AAC.GTT AG.CT AG.CT AAAT.ATTT AAAG.CTTT AAAG.CTTT AAAG.CTTT AAAG.CTTT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AC.GT AC.GT AAAAAC.GTTTTT AAAAT.ATTTT AAAG.CTTT AG.CT AT.AT AT.AT AC.GT AAAAT.ATTTT AT.AT AAAC.GTTT ATC.GAT AAAAG.CTTTT AAAC.GTTT AAAAAG.CTTTTT AAAC.GTTT AAAAT.ATTTT AAG.CTT AAAC.GTTT AC.GT AAC.GTT AG.CT AAAC.GTTT AC.GT AAAT.ATTT AG.CT AGGG.CCCT AC.GT AAAC.GTTT AAAAC.GTTTT AAAT.ATTT AAG.CTT AT.AT AC.GT AT.AT AC.GT ACAT.ATGT AC.GT AT.AT AAAAAG.CTTTTT AC.GT AT.AT

15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15

97625750 97644691 97752884 98100666 98317207 98380363 98398388 98844025 98975325 99097914 99298976 99318946 99389339 99457605 99536491 99571919 99651675 99657956 99723069 99731525 99954837 100369487 100570626 100574895 100596749 100610758 101143298 101151340 101276771 101325135 101494381 101538766 101622450 101684900 101684900 101684900 101684900 101712167 101712167 101712167 101712167 101721653 101731230 101731688 101798962 102048612 102219651 102232735 102247562 102253566 102263170 102350449 102554773 102574553 102603782 103075494 103471253 103575418 103645276 104526071 104529407 104683121 105463718 105474148 105721186 106372335 106380143 106799366 106885200 107100988 107270705 107292583 107333159 107463767 107627556 108241436 108359000 108503250 108512707 108608676 108640333 108722656 108814162 108956914

97625789 97644702 97752908 98100690 98317217 98380375 98398424 98844048 98975338 99097928 99298986 99318957 99389366 99457626 99536517 99571929 99651688 99657965 99723100 99731547 99954846 100369505 100570640 100574927 100596758 100610768 101143318 101151362 101276785 101325152 101494392 101538776 101622479 101684916 101684916 101684916 101684916 101712186 101712186 101712186 101712186 101721666 101731242 101731712 101798979 102048626 102219664 102232746 102247574 102253576 102263187 102350463 102554787 102574571 102603799 103075512 103471272 103575444 103645298 104526086 104529421 104683132 105463738 105474163 105721214 106372349 106380160 106799382 106885218 107101010 107270722 107292607 107333173 107463780 107627591 108241476 108359009 108503260 108512737 108608687 108640342 108722675 108814198 108956926

8 6 6.25 5 5.5 3.25 12.3333 6 3.5 7.5 5.5 6 5.6 4.4 6.75 5.5 3.5 5 8 5.75 5 9.5 5 16.5 5 5.5 10.5 4.6 3.75 6 6 5.5 7.5 4.25 4.25 4.25 4.25 6.66667 6.66667 6.66667 6.66667 7 6.5 4.16667 3.6 3.75 7 6 6.5 5.5 3.6 7.5 3.75 6.33333 3.6 4.75 3.33333 6.75 4.6 5.33333 3.75 6 7 8 7.25 7.5 4.5 8.5 4.75 11.5 4.5 5 3.75 4.66667 18 20.5 5 5.5 7.75 6 5 3.33333 18.5 6.5

. . ENSSSCT00000017440 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000017452 ENSSSCT00000017452 ENSSSCT00000035294 ENSSSCT00000035682 ENSSSCT00000034634 ENSSSCT00000017452 ENSSSCT00000035294 ENSSSCT00000035682 ENSSSCT00000034634 . ENSSSCT00000031268 ENSSSCT00000031268 ENSSSCT00000031268 . . . . . . . ENSSSCT00000017457 ENSSSCT00000017457 . . . . ENSSSCT00000017458 ENSSSCT00000017461 ENSSSCT00000017461 . ENSSSCT00000017470 ENSSSCT00000017470 . . . . . . ENSSSCT00000029791 . . . . ENSSSCT00000017490 ENSSSCT00000017490 . . . . . . .

. . DNAJC10 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ITGAV ITGAV ITGAV ITGAV ITGAV ITGAV ITGAV ITGAV ITGAV . FAM171B FAM171B FAM171B . . . . . . . TFPI TFPI . . . . . WDR75 WDR75 . PMS1 PMS1 . . . . . . . . . . . TMEFF2 TMEFF2 . . . . . . .

intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intron intron intron intergenic promoter promoter intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intron intron intron intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic

0.211 0.164 . 0.166 0.027 0.123 . -0.276 0.256 . 0.043 0.305 . -0.027 0.049 . . . . -0.177 . -0.011 0.083 -0.018 0.046 . 0.366 . 0.144 . 0.168 0.282 0.426 1.055 1.055 1.055 1.055 0.018 0.018 0.018 0.018 0.062 -0.209 0.028 0.789 . 0.004 . . 0.143 0.098 . 0.206 . -0.213 -0.06 . 0.117 0.088 . . . . 0.253 . 0.138 0.447 0.082 0.139 0.033 . -0.061 . -0.092 . 0.029 0.125 0.131 -0.345 -0.134 . . 0.43 0.091

438616 rs7933 790048 rs7890 354464 rs7889 rs790152023 . rs792282585 rs788991667 363203 rs7910 rs788493740 . rs791669658 . 739777 rs7933 rs789217690 789629 rs7921 . rs792122114 . rs787607789 939214 rs7908 rs787718106 634073 rs7912 . . rs792597673 . 938979 rs7895 514443 rs7938 116265 rs7923 rs787015818 rs789006702 . rs786596228 rs788391626 rs788391626 rs788391626 rs788391626 517364 rs7890 517364 rs7890 517364 rs7890 517364 rs7890 rs792945825 . rs788995502 rs793368581 rs789589410 rs791899848 rs791747265 rs788339154 rs790718071 . rs791204366 rs786564939 rs786917696 rs792673134 655684 rs7863 . rs789829095 rs791146168 rs789575893 . rs792737346 rs789011680 rs788857317 rs793235086 . 451923 rs7936 rs792941401 rs789960200 rs788611174 rs786849617 286016 rs7911 968439 rs7903 rs788759473 rs790116164 rs792369645 rs791250043 . rs793428285 . rs789282174 rs790286752 rs793817584 182863 rs7917

2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 4 2 2 3 2 2 2 3 3 3 2 2 2 2 2 2 2 2 2 4 2 2 2 2 4 2 3 2 2 2 2 2 2 2 2 2 2 2 2 4 2 4 2 2 2 4 2 2 2 2 2 2 2 4 3 3 2 3 3 2 2 3

AAT.ATT AAAAT.ATTTT AT.AT AT.AT AT.AT AAAT.ATTT AT.AT AGAT.ATCT AT.AT AAAT.ATTT AC.GT AAAC.GTTT AC.GT AAAC.GTTT AAAC.GTTT AC.GT AACCCT.AGGGT AC.GT AT.AT AAAAT.ATTTT AAAC.GTTT AAAT.ATTT AAAC.GTTT AAC.GTT AAAAAT.ATTTTT AC.GT AC.GT AAAC.GTTT AAC.GTT AC.GT AATG.CATT AAAG.CTTT AATG.CATT AAAAC.GTTTT AAT.ATT AC.GT AC.GT AC.GT AAAC.GTTT AAAC.GTTT AAAC.GTTT AT.AT AAAG.CTTT AAAC.GTTT AAAC.GTTT AAAAG.CTTTT AC.GT AAAC.GTTT AAAC.GTTT AT.AT AT.AT AAT.ATT AAC.GTT AT.AT AAAC.GTTT AC.GT AAAC.GTTT AAAC.GTTT AAAT.ATTT AAAG.CTTT AT.AT AG.CT AT.AT AT.AT AG.CT ATCC.GGAT AG.CT AATT.AATT AAT.ATT AAAC.GTTT AAAC.GTTT AC.GT AAAC.GTTT AT.AT AG.CT AC.GT AAAAC.GTTTT AT.AT AAAC.GTTT AG.CT AC.GT AC.GT AAC.GTT AAAAAT.ATTTTT

15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15

109191497 109403485 109410657 109549538 109573787 109841764 109874388 110295972 110306837 110310834 110347776 110781780 110838111 111051623 111064749 111999995 112024852 112089396 112130273 112332226 112354131 112451393 112483180 112506392 112553678 112868467 113022897 113077456 113195289 113199600 113275272 113532911 113593933 113616171 113725391 113762221 113932454 114124732 114160306 114602624 114810036 114813014 114938164 114975818 114977058 115273433 115297523 115358312 115491394 115498717 115589646 115729485 115737379 115827525 116098836 116118593 116212187 117416845 117445814 117461648 117748751 117761028 117858850 117944975 118505636 118706823 118816275 118857318 118881133 118991571 119178698 119186487 119249841 119274892 119283674 119307092 119387730 119651208 119807648 119823450 120472082 120666845 120709771 120942261

109191508 109403502 109410667 109549547 109573797 109841783 109874400 110296008 110306866 110310860 110347792 110781798 110838126 111051636 111064763 112000008 112024873 112089430 112130285 112332244 112354150 112451416 112483198 112506407 112553697 112868490 113022915 113077476 113195302 113199618 113275289 113532930 113593955 113616186 113725403 113762235 113932468 114124748 114160338 114602638 114810055 114813023 114938185 114975845 114977084 115273454 115297534 115358340 115491409 115498728 115589655 115729496 115737397 115827534 116098859 116118615 116212209 117416864 117445826 117461662 117748763 117761037 117858859 117944988 118505653 118706844 118816285 118857337 118881146 118991585 119178713 119186503 119249863 119274909 119283689 119307122 119387748 119651222 119807667 119823460 120472096 120666855 120709787 120942279

4 3.6 5.5 5 5.5 5 6.5 9.25 15 6.75 8.5 4.75 8 3.5 3.75 7 3.66667 17.5 6.5 3.8 5 6 4.75 5.33333 3.33333 12 9.5 5.25 4.66667 9.5 4.5 5 5.75 3.2 4.33333 7.5 7.5 8.5 8.25 3.75 5 5 5.5 7 6.75 4.4 6 7.25 4 6 5 4 6.33333 5 6 11.5 5.75 5 3.25 3.75 6.5 5 5 7 9 5.5 5.5 5 4.66667 3.75 4 8.5 5.75 9 8 15.5 3.8 7.5 5 5.5 7.5 5.5 5.66667 3.16667

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000017493 STK17B intron ENSSSCT00000028914 . promoter ENSSSCT00000025335 . promoter . . intergenic ENSSSCT00000017501 . intron ENSSSCT00000017501 . intron ENSSSCT00000017501 . intron ENSSSCT00000017501 . intron ENSSSCT00000017503 SF3B1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000017518 SPATS2L intron ENSSSCT00000017518 SPATS2L intron ENSSSCT00000017519 . intron ENSSSCT00000027335 AOX1 intron ENSSSCT00000027335 AOX1 intron . . intergenic . . intergenic ENSSSCT00000017522 BZW1 intron ENSSSCT00000017521 . intron . . intergenic ENSSSCT00000017531 FLIP-L intron . . intergenic . . intergenic ENSSSCT00000017544 BMPR2 intron ENSSSCT00000017544 BMPR2 intron . . intergenic . . intergenic ENSSSCT00000017547 WDR12 promoter . . intergenic . . intergenic ENSSSCT00000024007 ICOS intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000017554 . intron . . intergenic . . intergenic . . intergenic

-0.097 0.091 0.04 . -0.064 . -0.284 0.187 . . 0.677 0.057 . 0.285 0.081 0.164 . -0.077 0.264 0.289 0.14 0.316 0.238 . . 0.051 . -0.093 -0.313 0.064 0.145 -0.312 0.042 . . 0.193 0.056 0.609 0.188 . . 0.101 0.035 0.094 0 0.163 0.986 . -0.016 0.035 . -0.217 . 0.048 . . 0.022 . . . . . 0.147 0.212 1.948 0.168 0.285 -0.165 0.599 . 0.146 0.101 . -0.005 -0.125 . . -0.026 0.725 -0.048 -0.066 . 0.239 .

. rs792482748 rs792740216 . . rs789694109 547461 rs7879 731584 rs7888 rs789875629 375930 rs7901 rs787963884 rs786740604 042855 rs7921 294316 rs7887 202182 rs7872 rs788572402 rs793108681 688132 rs7874 rs789383769 rs790554071 rs789065721 rs793790133 rs793542383 756404 rs7910 rs788390624 rs787825690 rs787800778 rs793286634 rs788961736 697340 rs7938 rs792733667 . rs789183064 rs690870914 491167 rs7932 . rs790521332 rs789718198 . 124687 rs7903 rs786803074 . rs792073771 rs790978672 rs790228788 . 656915 rs7889 rs791739267 rs793097205 . . 437829 rs7886 rs793150996 . 786469 rs7896 rs793247754 rs786651658 rs793387572 rs791857228 767276 rs6962 rs792360520 . rs791566384 rs792168015 rs793397474 rs786547664 rs787317433 464511 rs7867 rs789498980 727904 rs7867 rs793163140 . rs792044808 rs793367622 rs792856383 rs786680174 rs789695395 rs790052483 rs790057807 . 341928 rs7871 rs788224087 rs790458004 rs788870431

2 2 3 4 2 2 2 2 2 3 2 2 2 2 2 2 2 3 3 2 2 2 3 2 2 4 2 2 2 3 2 2 2 2 2 4 2 2 4 2 3 3 2 2 2 2 2 2 2 2 3 2 4 2 2 2 2 2 2 2 3 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2

AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAAT.ATTTT AAAAG.CTTTT AAAAAG.CTTTTT AT.AT AAAG.CTTT AAAC.GTTT AAAAC.GTTTT AC.GT AAAC.GTTT AAAT.ATTT AG.CT AAC.GTT AG.CT AAAC.GTTT AAAAAG.CTTTTT AAAAAG.CTTTTT AC.GT AT.AT AAAT.ATTT AAC.GTT AC.GT AC.GT AC.GT AAAC.GTTT AC.GT AAAAC.GTTTT AT.AT AT.AT AAAAC.GTTTT AAT.ATT AT.AT AC.GT AC.GT AAAT.ATTT AAT.ATT AAAT.ATTT AAAC.GTTT AAC.GTT AAC.GTT AAC.GTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAAT.ATTTT AAAAT.ATTTT AG.CT AG.CT AC.GT AC.GT AG.CT AG.CT AG.CT AT.AT AC.GT AAC.GTT AC.GT AAAC.GTTT AG.CT AC.GT AAC.GTT AAT.ATT AAAT.ATTT AC.GT AT.AT AAT.ATT AAAG.CTTT AC.GT AAC.GTT AAT.ATT AT.AT AAAC.GTTT AAAT.ATTT AAT.ATT AG.CT AAC.GTT ACCT.AGGT AAC.GTT AG.CT AT.AT AAAAAC.GTTTTT

15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15

121002793 121002793 121002793 121176010 121204412 121448643 121525816 121535733 121668445 121930930 121945475 122027580 122117248 122150011 122187663 122197176 122290296 122324222 122373547 122414927 122568454 122839978 122866014 122939050 122947648 122968164 123148514 123206204 123266809 123393198 123484761 123537363 123638217 123684816 123839468 123903359 123920586 123953245 124013974 124061325 124088928 124220854 124220854 124266384 124266384 124366837 124366837 124384441 124384441 124425186 124425186 124431066 124431066 124625284 124625284 124625284 124910138 125140661 125339179 125491436 125551210 125769237 125926827 125940029 125989313 126072565 126174829 126307265 126391992 126943131 127092595 127273680 127299191 127405836 127410267 127809072 127888251 127977067 128088030 128344102 128386939 128480964 128650188 128747966

121002807 121002807 121002807 121176029 121204435 121448667 121525826 121535751 121668459 121930953 121945489 122027596 122117266 122150028 122187679 122197188 122290318 122324245 122373572 122414946 122568473 122839990 122866027 122939070 122947659 122968174 123148530 123206216 123266845 123393210 123484770 123537383 123638242 123684835 123839484 123903369 123920603 123953282 124014002 124061344 124088948 124220869 124220869 124266408 124266408 124366849 124366849 124384459 124384459 124425202 124425202 124431078 124431078 124625300 124625300 124625300 124910149 125140681 125339194 125491448 125551224 125769250 125926837 125940048 125989336 126072595 126174851 126307289 126392009 126943145 127092609 127273691 127299209 127405847 127410293 127809098 127888271 127977078 128088043 128344124 128386964 128480978 128650218 128747988

3.75 3.75 3.75 4 4.8 4.16667 5.5 4.75 3.75 4.8 7.5 4.25 4.75 9 5.66667 6.5 5.75 4 4.33333 10 10 3.25 4.66667 10.5 6 5.5 4.25 6.5 7.4 6.5 5 4.2 8.66667 10 8.5 5.5 4.5 12.6667 7.25 5 7 5.33333 5.33333 6.25 6.25 3.25 3.25 3.8 3.8 8.5 8.5 6.5 6.5 8.5 8.5 8.5 6 10.5 5.33333 6.5 3.75 7 5.5 6.66667 8 7.75 11.5 12.5 6 3.75 7.5 4 6.33333 6 6.75 6.75 7 6 4.66667 5.75 8.66667 7.5 15.5 3.83333

ENSSSCT00000017560 ENSSSCT00000020378 ENSSSCT00000021282 . . ENSSSCT00000017564 . . . . . . . . . . . . ENSSSCT00000025237 . ENSSSCT00000022797 . ENSSSCT00000026412 ENSSSCT00000017580 ENSSSCT00000017580 ENSSSCT00000017580 ENSSSCT00000017581 . . . . . . . . . . . . . . ENSSSCT00000017586 ENSSSCT00000030483 ENSSSCT00000017586 ENSSSCT00000030483 ENSSSCT00000017586 ENSSSCT00000030483 ENSSSCT00000017586 ENSSSCT00000030483 ENSSSCT00000017586 ENSSSCT00000030483 ENSSSCT00000017586 ENSSSCT00000030483 ENSSSCT00000029240 ENSSSCT00000025006 ENSSSCT00000031966 . . . . . . ENSSSCT00000027992 ENSSSCT00000027992 . . ENSSSCT00000017595 . . . . . . . . . . . . . . . . .

EEF1B2 intron snoZ196 promoter SNORA41 promoter . intergenic . intergenic ADAM23 intron . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic METTL21A 3'utr . intergenic . intron . intergenic IDH1 intron PIKFYVE intron PIKFYVE intron PIKFYVE intron PTH2R intron . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic UNC80 intron UNC80 intron UNC80 intron UNC80 intron UNC80 intron UNC80 intron UNC80 intron UNC80 intron UNC80 intron UNC80 intron UNC80 intron UNC80 intron KANSL1L intron KANSL1L intron KANSL1L intron . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intron . intron . intergenic . intergenic . intron . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic

4.2 4.2 4.2 0.145 . -0.002 0.475 0.103 0.022 0.183 0.607 0.416 -0.016 1.026 -0.105 0.372 . 0.534 0.29 0.214 0.109 0.027 1.615 0.212 . . 0.128 . . . 0.13 0.197 -0.03 . 0.007 0.283 0.019 0.239 . 0.507 0.082 -0.08 -0.08 0.096 0.096 0.256 0.256 0.044 0.044 0.328 0.328 0.204 0.204 0.217 0.217 0.217 0.219 . -0.022 0.131 -0.019 -0.042 -0.068 -0.137 0.035 0.145 -0.106 0.001 -0.142 -0.089 -0.085 . -0.132 1.273 0.207 0.125 0.17 0.876 . 0.237 . 0.301 0.054 -0.111

rs791434178 rs791434178 rs791434178 rs793494655 rs788674562 . . 637956 rs7911 324278 rs7907 813851 rs7886 . 813866 rs7877 . rs788382420 rs790520205 rs790368228 rs793042700 040437 rs7934 rs789559994 . 209632 rs7910 rs789472264 rs793724428 rs787951199 . rs787280776 rs790183989 . rs791613716 rs790719904 rs789113459 rs791740796 rs792979141 rs791016705 679550 rs7871 rs786410197 355286 rs7921 rs787412146 437597 rs7889 605097 rs7881 234825 rs7914 729699 rs7897 729699 rs7897 rs791516435 rs791516435 982478 rs7873 982478 rs7873 587053 rs7911 587053 rs7911 rs792284114 rs792284114 rs786726237 rs786726237 rs788010873 rs788010873 rs788010873 . . 685248 rs7908 . 620536 rs7917 060499 rs7911 rs789442837 rs789773521 rs792938575 rs787276346 . 391647 rs7914 rs789061113 rs787713420 rs786515342 rs791642174 rs792230351 572288 rs7928 125571 rs7931 rs793591478 814510 rs7931 rs787610732 rs790124933 rs793018247 rs791258576 . rs791806284 rs786701728

2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 5 2 3 4 2 4 2 2 2 2 2 2 2 2 3 2 2 2 2 2 4 2 2 2 2 2 2 2 2 3 3 2 2 2 2 2 2 2 2 4 2 3 2 2 2 2 6 2 2 2 2 2 2 3 2 2 2 2 3 2 2 2 2 2

AAC.GTT AT.AT AAC.GTT AAC.GTT AAAAAT.ATTTTT AT.AT AAAC.GTTT AAAAG.CTTTT AT.AT AG.CT AC.GT ATC.GAT AAC.GTT AC.GT AC.GT AG.CT AAAC.GTTT AT.AT AG.CT AAAAT.ATTTT AG.CT AC.GT AAAC.GTTT AAC.GTT AAC.GTT AAAC.GTTT AG.CT AT.AT AAG.CTT AAG.CTT AAAC.GTTT AC.GT AG.CT AAT.ATT AAGG.CCTT AAAAG.CTTTT AC.GT AG.CT ATCC.GGAT AG.CT AC.GT AC.GT AT.AT AAAAAC.GTTTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AT.AT AAGG.CCTT AC.GT AG.CT AAAAC.GTTTT AAAC.GTTT AG.CT AAAT.ATTT AAAG.CTTT AGG.CCT AAT.ATT AAAG.CTTT AAAG.CTTT AAAC.GTTT AAT.ATT AT.AT AAC.GTT AAG.CTT AAAAG.CTTTT AAAAG.CTTTT AC.GT AAAT.ATTT AAAT.ATTT AAAT.ATTT AC.GT ACAT.ATGT AAAAG.CTTTT AAAC.GTTT AAAAT.ATTTT AAAC.GTTT AAAAC.GTTTT AAATG.CATTT AAC.GTT AAAT.ATTT AAAC.GTTT AT.AT AG.CT

15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15

128995624 129377393 129544788 129546602 129566300 129576559 129577752 129686945 129709107 130440174 130607462 130752031 131052471 131182674 131490529 131652973 131820398 131842442 132618887 132658135 132775836 133250493 133477499 133822441 133822441 134257965 134761723 134808887 135236177 135250247 135354595 135361203 135397119 135402649 135465667 135898651 135957380 135978378 136127507 136136511 136154645 136338461 136338904 136473220 136520783 136649364 137044900 137065803 137087797 137101018 137132053 137196361 137216831 137428177 137438937 137682720 137701254 137855481 137936064 137960242 137969686 137973918 138585721 139030955 139100890 139204125 139204125 139275707 139291369 139309245 139327230 139365057 139459242 139579527 139605261 139793007 139834560 139977808 139981195 140056559 140216073 140222140 140549396 140611525

128995644 129377403 129544801 129546617 129566319 129576568 129577770 129686970 129709124 130440184 130607471 130752057 131052487 131182690 131490557 131652984 131820410 131842457 132618908 132658154 132775846 133250509 133477514 133822455 133822455 134257979 134761739 134808897 135236196 135250261 135354609 135361215 135397133 135402670 135465693 135898669 135957390 135978394 136127528 136136530 136154657 136338493 136338913 136473248 136520805 136649380 137044915 137065817 137087823 137101027 137132071 137196378 137216852 137428200 137438954 137682738 137701267 137855494 137936093 137960255 137969700 137973935 138585731 139030968 139100909 139204143 139204143 139275718 139291391 139309262 139327247 139365071 139459266 139579549 139605275 139793031 139834582 139977837 139981213 140056572 140216099 140222158 140549407 140611534

7 5.5 4.66667 5.33333 3.33333 5 4.75 5.2 9 5.5 5 9 5.66667 8.5 14.5 6 3.25 8 11 4 5.5 8.5 4 5 5 3.75 8.5 5.5 6.66667 5 3.75 6.5 7.5 7.33333 6.75 3.8 5.5 8.5 5.5 10 6.5 16.5 5 4.83333 5.75 4.25 4 7.5 6.75 5 9.5 3.6 5.5 12 4.5 4.75 4.66667 4.66667 7.5 3.5 3.75 6 5.5 4.66667 6.66667 3.8 3.8 6 5.75 4.5 4.5 7.5 6.25 4.6 3.75 5 5.75 6 3.8 4.66667 6.75 4.75 6 5

. . . . . . . . . . . . ENSSSCT00000017612 ENSSSCT00000028863 . . . . . . . ENSSSCT00000017620 ENSSSCT00000017637 ENSSSCT00000032395 ENSSSCT00000031662 ENSSSCT00000017654 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000017668 ENSSSCT00000017668 . . . ENSSSCT00000017676 ENSSSCT00000036636 . . . . . . . . . . ENSSSCT00000017680 ENSSSCT00000017680 ENSSSCT00000017680 . . ENSSSCT00000017682 ENSSSCT00000017682

. . . . . . . . . . . . MREG PECR . . . . . . . RUFY4 VIL1 . . GLB1L . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PN-1 PN-1 . . . . . . . . . . . . . . . NYAP2 NYAP2

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron promoter intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intron intron

0.045 . -0.001 . 0.087 . 0.086 0.277 -0.081 . -0.003 0.018 . 0.144 0.039 . 0.074 -0.011 -0.312 -0.093 1.068 -0.13 . . . 0.065 -0.053 0.057 0.386 -0.071 0.129 0.266 -0.077 1.518 0.007 1.663 -0.159 . -0.158 -0.009 -0.013 -0.123 -0.047 0.117 0.003 -0.039 . 0.152 0.06 . 0.107 -0.225 . -0.021 0.179 0.455 -0.105 0.086 0.147 -0.188 0.092 0.228 -0.234 . . -0.248 -0.248 0.151 0.576 . -0.486 0.025 -0.06 -0.103 -0.012 0.07 0.019 -0.181 -0.035 . -0.02 -0.115 . -0.201

641136 rs7932 rs786659537 rs788579348 . . . 770378 rs7865 615689 rs7863 463845 rs7925 rs790056433 . rs788107186 170863 rs7923 rs793625575 rs791366203 rs789426217 rs792824034 . 592660 rs7903 rs787778090 rs788844613 . rs793873913 . . rs787468597 rs793758891 rs790597621 rs788642913 824102 rs7916 rs787558168 . rs787396458 161516 rs7933 rs786582615 rs789090798 . . 858927 rs7888 rs793370809 rs788798023 rs793785114 . rs792761591 148725 rs7868 rs786563860 297032 rs7905 . 719408 rs7934 rs692147440 . rs789669619 rs787717379 . 066256 rs7874 rs787411539 rs790191279 rs789242092 rs790239524 rs787309802 rs788067326 rs786778572 . rs791106912 rs791614943 rs792865622 rs792865622 . rs788604842 rs793172179 rs788996463 rs793001972 . . 936829 rs7897 rs790207634 rs787836528 rs790790857 rs791916773 919323 rs7890 rs789477380 rs786766489 rs792087984 rs789082819

2 3 2 2 2 2 2 2 4 3 2 4 2 2 2 2 2 2 4 2 2 2 2 4 4 2 2 2 2 2 2 2 2 2 2 2 3 4 3 2 2 3 3 2 2 2 2 4 3 4 3 2 2 2 2 2 2 2 2 2 2 4 4 2 2 2 2 3 2 3 2 2 2 2 3 2 2 2 2 2 3 2 2 2

AT.AT AC.GT AAG.CTT ACACCC.GGGTG AT.AT AAT.ATT AC.GT AGCT.AGCT AAAAC.GTTTT AAG.CTT AAAC.GTTT AAAC.GTTT AAT.ATT AAAAG.CTTTT AAT.ATT AG.CT AAAC.GTTT AAAAC.GTTTT AT.AT AAAC.GTTT AC.GT AG.CT AAAG.CTTT AAAAG.CTTTT AAAAG.CTTTT AAC.GTT AC.GT AT.AT AAAC.GTTT AAAAAT.ATTTTT AAAC.GTTT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT ACAG.CTGT AAAC.GTTT AC.GT AAAT.ATTT AAAG.CTTT AAC.GTT AATC.GATT AAAC.GTTT AC.GT AAAC.GTTT AC.GT AAAC.GTTT AC.GT AC.GT AC.GT ACAG.CTGT AC.GT AAC.GTT AAAC.GTTT AAAC.GTTT AC.GT AG.CT AATG.CATT AAAC.GTTT AAAG.CTTT AC.GT AC.GT AAAAC.GTTTT AAAAC.GTTTT AAC.GTT AAAC.GTTT AC.GT AAAC.GTTT AACAG.CTGTT AC.GT AG.CT AT.AT AAAT.ATTT AAT.ATT AC.GT AT.AT AC.GT AG.CT AT.AT AAAC.GTTT AC.GT AG.CT AAAAAT.ATTTTT AAAAT.ATTTT AAAAC.GTTTT

15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 15 16

140633616 140642691 140784227 141163693 141423858 141514377 141800338 141809488 141862613 142016956 142513121 142513121 142734438 143073126 143088629 143179730 143337154 143687576 143899014 144095988 144292705 144363289 144937897 145199833 145213684 145308449 145383217 145427359 145573620 145962668 145966800 145978027 146079894 146537944 146556448 146576038 146726837 147104600 147664543 148177811 148181045 148850029 149171800 149395876 149666631 149699379 149933352 150362355 150439555 150627874 150738952 150766627 150935524 151054587 151238615 151252736 151446281 151490981 151557585 151641080 151680850 151700853 151765685 151965568 151991076 152040314 152305388 152576491 153502186 153563071 154289335 154819785 155885930 155911454 156592062 156599466 156614421 156616544 156702066 156816275 157103681 157104262 157411913 309158

140633637 140642703 140784241 141163723 141423878 141514395 141800352 141809507 141862634 142016969 142513139 142513139 142734452 143073145 143088652 143179742 143337173 143687599 143899024 144096002 144292726 144363301 144937916 145199861 145213706 145308466 145383227 145427374 145573635 145962685 145966815 145978042 146079908 146537968 146556470 146576058 146726859 147104622 147664556 148177823 148181063 148850043 149171814 149395891 149666649 149699400 149933363 150362366 150439593 150627895 150738963 150766644 150935540 151054605 151238632 151252747 151446306 151490994 151557598 151641091 151680866 151700871 151765707 151965587 151991094 152040326 152305406 152576510 153502198 153563090 154289345 154819801 155885943 155911465 156592072 156599475 156614435 156616553 156702101 156816286 157103690 157104285 157411930 309182

11 6.5 5 5.16667 10.5 6.33333 7.5 5 4.4 4.66667 4.75 4.75 5 4 8 6.5 5 4.8 5.5 3.75 11 6.5 5 5.8 4.6 6 5.5 8 4 3 4 3.2 3.75 6.25 5.75 5.25 11.5 5.75 3.5 4.33333 4.75 3.75 7.5 4 9.5 5.5 6 6 19.5 5.5 6 6 4.25 4.75 9 6 6.5 3.5 3.5 6 8.5 3.8 4.6 6.66667 4.75 6.5 4.75 4 6.5 10 5.5 4.25 4.66667 6 5.5 5 7.5 5 9 6 5 4 3.6 5

ENSSSCT00000017682 . . . . . . . . . ENSSSCT00000017689 ENSSSCT00000026444 . . . . ENSSSCT00000017701 . . . . . ENSSSCT00000017707 ENSSSCT00000017712 ENSSSCT00000017712 . . ENSSSCT00000017717 ENSSSCT00000017721 . . . . ENSSSCT00000026575 ENSSSCT00000026575 ENSSSCT00000026575 ENSSSCT00000026675 ENSSSCT00000017739 ENSSSCT00000017748 ENSSSCT00000017756 ENSSSCT00000017756 . . . . . ENSSSCT00000022776 ENSSSCT00000017770 . . ENSSSCT00000017774 . . . . . . ENSSSCT00000028799 . . . . ENSSSCT00000017783 . ENSSSCT00000025350 . . . . . . . . . . . . . . . . . ENSSSCT00000017856 ENSSSCT00000018267

NYAP2 . . . . . . . . . . . . . . . SPHKAP . . . . . SP140 . . . . SPATA3 HTR2B . . . . DIS3L2 DIS3L2 DIS3L2 . EFHD1 INPP5D MROH2A MROH2A . . . . . . AGAP1 . . IQCA1 . . . . . . COL6A3 . . . . . . . . . . . . . . . . . . . . . . . . STAM2 CTNND2

intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intron intron intergenic intergenic intergenic intergenic intron intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intron intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron

0.5 -0.034 -0.182 -0.069 . -0.09 0.081 0.065 0.241 0.045 0.325 0.325 0.114 0.041 -0.217 . 0.005 . -0.016 . 0.054 -0.094 -0.911 0.161 -0.046 . 0.112 -0.242 0.284 0.185 0.083 0.183 0.004 0.047 0.206 . -0.173 -0.211 . -0.161 -0.179 . -0.34 . . -0.246 -0.115 -0.262 . 0.037 -0.033 -0.343 -0.447 -0.013 -0.063 0.206 . . -0.099 -0.055 -0.185 -0.524 . . 0.564 . 0.054 . . -0.333 -0.325 . . . . . -0.242 -0.092 . . . 0.048 . -0.193

rs792742109 rs786654640 rs790075590 rs789539416 . rs793862751 rs788499365 rs790283056 . rs787829493 644265 rs7921 644265 rs7921 rs789639183 rs786799239 . rs788620477 656261 rs7889 rs789578302 rs793294371 rs787771843 . . 949267 rs7892 rs789995387 rs793132912 421120 rs7862 rs791115370 . 759871 rs7879 rs788583615 rs787880291 348501 rs7901 rs790378726 rs792711253 rs787792615 202864 rs7889 275005 rs7863 rs792894506 rs792433147 rs790820110 rs792760060 604165 rs7920 438402 rs7910 rs790915493 rs789866181 rs791094873 015502 rs7927 rs788241131 rs792052557 rs790020441 . 692006 rs7877 . rs694576010 164749 rs7908 rs788319938 rs792541698 014260 rs7884 . rs789959989 rs788041648 rs787466862 366741 rs7920 rs787234052 063664 rs7927 rs789970529 rs696463367 rs793421777 rs793007606 625811 rs7876 523139 rs7920 . 364731 rs7877 . rs792152734 . rs792550356 rs791537309 683084 rs7915 rs791462845 . . . rs790276146

2 6 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 3 2 2 3 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 3 3 2 2 2 2 2 3 2 2 2 2 2 3 2 2 2 5 2 2 2 2 2 2 2 2 2 2 4 2 3 2

AAAAC.GTTTT AT.AT AAT.ATT AC.GT AC.GT AAC.GTT AC.GT AAAT.ATTT ATC.GAT AATG.CATT AAAC.GTTT AAC.GTT AT.AT AT.AT AT.AT AAAT.ATTT AAAT.ATTT AC.GT AC.GT AT.AT AAAC.GTTT AAAAC.GTTTT AAAT.ATTT AAAC.GTTT AG.CT AC.GT AC.GT AC.GT AG.CT AT.AT ACAG.CTGT AC.GT AC.GT ACG.CGT AC.GT AAAT.ATTT AGC.GCT AC.GT AAAC.GTTT AG.CT AT.AT AAAAAC.GTTTTT ATC.GAT AGAGAT.ATCTCT AAAAT.ATTTT ACAT.ATGT AT.AT AAAC.GTTT AT.AT AC.GT AC.GT AAC.GTT AAC.GTT AC.GT AAG.CTT AG.CT AAAG.CTTT AAAC.GTTT AAAT.ATTT AT.AT AAAC.GTTT AAAAC.GTTTT ACC.GGT AG.CT AAAT.ATTT ACC.GGT AAAAC.GTTTT AC.GT AAATT.AATTT AG.CT AAAAC.GTTTT AAAAAG.CTTTTT AC.GT AT.AT AAC.GTT AC.GT ACAG.CTGT AAAAAC.GTTTTT AG.CT AAC.GTT AG.CT AC.GT AAAC.GTTT AC.GT

16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16

473932 521163 536036 627113 640395 655163 907214 973076 1017559 1025409 1128943 1142023 1607813 1681383 1704183 2371030 2375310 2491482 2642753 2671641 2676988 2690869 2717331 2764253 2960239 3117660 3228715 3281457 3285377 3575752 3581051 3840208 3956502 4250859 4346952 4382412 4419386 4424116 4572927 4637163 4651909 4761147 4786171 4918486 4959088 5096334 5174080 5279899 5311119 5487186 5582903 5642930 5740511 5853796 5932047 6176524 6287099 6346092 6448575 6453656 6508460 6526660 6623494 6644920 6691592 6827287 6886409 7030195 7099861 7194013 7580806 7675239 7713286 7716195 8057692 8148959 8230603 8354460 8429112 8431359 8467095 8598983 8690535 8693728

473955 521174 536049 627122 640407 655177 907227 973096 1017577 1025434 1128965 1142036 1607832 1681397 1704193 2371043 2375338 2491494 2642763 2671650 2677007 2690884 2717345 2764267 2960249 3117672 3228724 3281471 3285390 3575761 3581074 3840218 3956528 4250873 4346962 4382423 4419401 4424135 4572946 4637191 4651919 4761168 4786199 4918505 4959114 5096354 5174089 5279926 5311131 5487196 5582914 5642941 5740528 5853818 5932061 6176540 6287113 6346111 6448596 6453665 6508482 6526675 6623512 6644931 6691619 6827306 6886430 7030212 7099881 7194023 7580830 7675263 7713309 7716214 8057711 8148982 8230625 8354489 8429121 8431370 8467105 8598995 8690549 8693739

4.8 6 4.66667 5 6.5 5 7 5.25 6.33333 6.5 5.75 4.66667 10 7.5 5.5 3.5 7.25 6.5 5.5 5 5 3.2 3.75 3.75 5.5 6.5 5 7.5 7 5 6 5.5 13.5 5 5.5 3 5.33333 10 5 14.5 5.5 3.66667 9.66667 3.33333 5.4 5.25 5 7 6.5 5.5 6 4 6 11.5 5 8.5 3.75 5 5.5 5 5.75 3.2 6.33333 6 7 6.66667 4.4 9 4.2 5.5 5 4.16667 12 10 6.66667 12 5.75 5 5 4 5.5 6.5 3.75 6

ENSSSCT00000018267 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000024898 ENSSSCT00000024898 ENSSSCT00000018268 . . ENSSSCT00000018270 ENSSSCT00000018270 ENSSSCT00000018271 . . . . . . . . . . . ENSSSCT00000025512 . . . . ENSSSCT00000018280 ENSSSCT00000018280 . ENSSSCT00000018282 ENSSSCT00000018282 . . . . . . . . . . . . . . . . . . . . . . . .

CTNND2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . FAM105B FAM105B ANKH . . . . . . . . . . . FBXL7 . . . . FAM134B FAM134B . MYO10 MYO10 . . . . . . . . . . . . . . . . . . . . . . . .

intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic promoter intergenic intergenic intergenic intergenic intron intron intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

0.003 -0.179 0.087 -0.385 -0.166 . -0.21 0.121 . . . 0.491 . -0.105 . 0.093 -0.13 -0.208 . -0.16 -0.087 0.116 . . 0.129 -0.232 0.023 0.21 -0.14 0.425 -0.108 1.004 -0.314 -0.169 0.309 . 1.291 -0.174 0.087 . . -0.097 0.101 0.012 0.123 . -0.019 0.047 0.431 -0.246 0.052 0.641 . 0.042 -0.108 -0.037 -0.125 0.132 0.088 -0.252 . -0.314 . . . -0.061 -0.2 0.088 . 0.107 0.277 -0.046 -0.106 -0.175 . 0.245 -0.195 -0.121 -0.123 0.028 . -0.203 -0.046 0.03

rs791213137 . rs789600614 . 889603 rs7901 rs786925278 rs790935284 rs791986786 511125 rs7916 rs787894830 528796 rs7905 rs789368904 . rs789032240 . . 272086 rs7888 916235 rs7922 rs790740427 . rs792404444 rs789481396 985466 rs7897 rs788006491 . 293736 rs7938 . rs789691695 rs792332638 . 195240 rs7934 rs792841631 rs791404009 rs787305763 . rs789602007 . rs788760721 163330 rs7933 725772 rs7903 rs792904217 rs789603936 rs793362052 570792 rs7928 rs787866680 rs789148362 . rs792878887 194423 rs7920 . . 109891 rs7899 903888 rs7865 008461 rs7881 rs789484523 477225 rs7921 076093 rs7896 305284 rs7123 rs703485085 608113 rs7931 rs791626591 rs792797476 rs791882449 rs789904231 rs791900336 048379 rs7888 rs793178988 rs787747886 rs793534604 rs792903793 813087 rs7897 654083 rs7864 . rs697011415 721295 rs7899 rs791690521 rs789692052 rs791919519 rs786617499 rs790770439 . rs788640291 rs788507743 .

2 2 3 2 3 2 5 2 2 2 2 2 2 2 4 2 2 2 4 4 2 2 2 2 2 2 2 3 4 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 3 2 2 2 2 2 3 2 2 2 2 2 2 2 2 3 3 2 3 2 3 2 2 2 2 2 5 2 2 3 2 3 2 2 3

AC.GT AC.GT ATC.GAT AC.GT AAAT.ATTT AAAC.GTTT ACAT.ATGT AT.AT AC.GT AC.GT AT.AT AAG.CTT AAAAT.ATTTT AAAT.ATTT AAAAAC.GTTTTT AG.CT AAAC.GTTT AC.GT AAAC.GTTT AAAC.GTTT AAC.GTT AAT.ATT AG.CT AC.GT AT.AT AAT.ATT AAAC.GTTT AAAC.GTTT AC.GT AAAT.ATTT AC.GT AC.GT AAC.GTT AT.AT AC.GT AG.CT AT.AT AT.AT AAAG.CTTT AAAAG.CTTTT ATC.GAT AAG.CTT AAAAT.ATTTT AT.AT AG.CT AATG.CATT AC.GT AC.GT AT.AT AAAT.ATTT AAAAC.GTTTT AAT.ATT AT.AT AG.CT AAAAG.CTTTT AAAC.GTTT AT.AT AT.AT AGAT.ATCT AAAC.GTTT AAAC.GTTT AAAC.GTTT ATC.GAT AC.GT AC.GT ATC.GAT AAT.ATT AC.GT AAAT.ATTT AAAG.CTTT AGAT.ATCT AAAC.GTTT AAAT.ATTT AAT.ATT AT.AT AG.CT AC.GT AAAC.GTTT AAC.GTT AG.CT AAT.ATT AC.GT AT.AT AT.AT

16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16

9028466 9042390 9077186 9114968 9171554 9345692 9630025 9649892 9713002 9806498 9879197 9964461 9965769 10193803 10261217 10353184 10378230 10481635 10485298 10853196 10973179 11063148 11081529 11253367 11258926 11342899 11359455 11368974 11585318 11684938 11809894 11964585 12057667 12107893 12321417 12384646 12478535 12497569 12564187 12581037 12619269 12639676 12705040 12793460 12821624 12854739 12909375 12925377 12997461 13106103 13180022 13187780 13202075 13380232 13383293 13555016 13584326 13813393 13861193 13872006 14056664 14066128 14174111 14190426 14195327 14224935 14428706 14435043 14448490 14473703 14586825 14621908 14895181 14923378 15050640 15160863 15381544 15441632 15585174 15815422 15867892 15902892 16075211 16163378

9028476 9042399 9077206 9114981 9171575 9345706 9630041 9649902 9713014 9806510 9879206 9964474 9965788 10193817 10261252 10353212 10378257 10481648 10485317 10853210 10973195 11063176 11081539 11253389 11258935 11342913 11359470 11369009 11585328 11684952 11809908 11964597 12057681 12107906 12321427 12384669 12478544 12497581 12564230 12581067 12619289 12639697 12705062 12793471 12821640 12854758 12909390 12925395 12997476 13106119 13180049 13187794 13202089 13380243 13383314 13555034 13584337 13813402 13861209 13872025 14056686 14066142 14174136 14190440 14195356 14224954 14428723 14435052 14448501 14473734 14586844 14621928 14895202 14923396 15050649 15160873 15381559 15441672 15585193 15815436 15867908 15902925 16075224 16163389

5.5 5 7 7 5.5 3.75 4.25 5.5 6.5 6.5 5 4.66667 4 3.75 6 14.5 7 7 5 3.75 5.66667 9.66667 5.5 11.5 5 5 4 9 5.5 3.75 7.5 6.5 5 7 5.5 12 5 6.5 11 6.2 7 7.33333 4.6 6 8.5 5 8 9.5 8 4.25 5.6 5 7.5 6 4.4 4.75 6 5 4.25 5 5.75 3.75 8.66667 7.5 15 6.66667 6 5 3 8 5 5.25 5.5 6.33333 5 5.5 8 10.25 6.66667 7.5 5.66667 17 7 6

. . . . . . . . . . . . . . . . . . . ENSSSCT00000018288 . ENSSSCT00000024837 ENSSSCT00000024837 . . . . . . . . . . . . . . . . . . ENSSSCT00000018292 ENSSSCT00000018292 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000028848 ENSSSCT00000028848 . . . . . . . . . .

. . . . . . . . . . . . . . . . . . . CDH12 . . . . . . . . . . . . . . . . . . . . . CDH10 CDH10 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . CDH9 CDH9 . . . . . . . . . .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

-0.326 -0.123 -0.24 . . . -0.026 -0.029 . 0.033 . -1.362 -0.136 0.062 -0.084 -0.098 . . -0.338 . -0.002 -0.101 -0.23 -0.251 . -0.133 . -0.02 0.153 0.002 -0.136 -0.074 0.016 -0.083 -0.209 -0.245 . 0.225 -0.346 -0.37 -0.076 0.126 -0.11 . 0.143 -0.244 -0.237 -0.148 . -0.31 . -0.142 -0.056 -0.139 0.093 -0.106 0.046 . -0.076 -0.047 . 0.05 -0.12 -0.185 -0.015 0.04 -0.061 -0.001 . 0.108 . 0.125 -0.058 -0.399 . -0.277 -0.01 . 0.087 0.01 . -0.005 . 0.176

. . rs787543657 621395 rs7911 rs791012944 481233 rs7876 rs787672581 615771 rs7922 rs793286454 . 171269 rs7897 rs793567075 572467 rs7866 rs788168343 rs790717861 . . . rs791487507 530015 rs7882 368614 rs7864 rs788477452 rs789058157 rs789367670 rs789794638 rs789735987 rs791537725 rs790020123 . 121586 rs7879 rs788930911 . . rs699842846 rs692348225 . . rs695844130 rs787476019 rs793131971 rs791528234 . rs793204012 rs792270042 . rs792750542 . 350247 rs7872 rs789800598 rs787916562 rs788616181 rs787031963 656217 rs7880 rs789446738 rs786574676 rs791875481 rs793392703 . rs793343251 rs792305471 018693 rs7931 . 441009 rs7878 rs793546604 . rs787987974 . 292502 rs7039 953455 rs7915 rs786792168 rs791694655 . rs790854445 rs792653896 . . rs788491442 rs792839439 rs787664091 rs788790178 . rs788205687 rs788220698 rs786484447

3 3 4 2 2 2 2 2 2 4 2 2 2 2 2 2 2 3 2 2 2 2 3 3 3 2 2 2 2 2 2 3 2 3 3 2 2 2 2 2 2 4 2 3 4 2 2 4 2 2 2 2 3 3 2 2 2 3 3 2 2 2 2 2 2 3 2 2 2 3 2 2 2 2 2 2 2 3 3 2 3 2 2 3

AC.GT AT.AT AAAT.ATTT AG.CT AAAC.GTTT AT.AT AT.AT AAAC.GTTT AATT.AATT AC.GT AC.GT AAAC.GTTT AT.AT AC.GT AAT.ATT AAAACT.AGTTTT AAAC.GTTT AAAAC.GTTTT AAAG.CTTT AC.GT AAAAT.ATTTT AC.GT AGG.CCT AAAC.GTTT AG.CT AAAAT.ATTTT AG.CT AT.AT AC.GT AAAC.GTTT AC.GT AAAT.ATTT AAAC.GTTT AAAC.GTTT AC.GT AAAAC.GTTTT AAGG.CCTT AAC.GTT AAAAAC.GTTTTT ATC.GAT AAAC.GTTT AAAT.ATTT AT.AT AAC.GTT ACAT.ATGT AT.AT AGGG.CCCT AAAC.GTTT AAAAC.GTTTT AG.CT AT.AT AAATT.AATTT AAT.ATT AC.GT AC.GT AG.CT AG.CT AAAC.GTTT AAAC.GTTT AG.CT AC.GT AAGG.CCTT AAAAC.GTTTT AAAAAG.CTTTTT AAAG.CTTT AAAAT.ATTTT AAAAT.ATTTT AAAAT.ATTTT ACC.GGT ACC.GGT ACC.GGT AAAAAC.GTTTTT AAAT.ATTT AAAT.ATTT AAT.ATT AT.AT AG.CT AAC.GTT AG.CT AC.GT AT.AT AAAGAG.CTCTTT AAAC.GTTT AC.GT

16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16

16748535 17456640 17678087 17861771 17878770 18027597 18068795 18069066 18144010 18166492 18267045 18465271 18502731 18516696 18517369 18603529 18612083 18626426 18629793 18821598 18838325 18897410 18950686 19614629 19636178 19660644 19686652 19780837 19859545 19920601 20014551 20704677 20804414 21084663 21111919 21211220 21513251 21877935 21985263 22237873 23150409 23225572 23579597 23871211 23908694 23942337 23976009 24317674 24331156 24495957 24496412 24500647 24529872 24766881 24766881 24820375 24820375 24995854 24995854 25025063 25053067 25120983 25152658 25213314 25235646 25536710 25536710 25536710 25574391 25574391 25574391 25715388 25806647 25806647 26238611 26252325 26352599 26367838 26443759 26445577 26445988 26678259 26788633 26849811

16748545 17456651 17678113 17861798 17878811 18027606 18068814 18069079 18144031 18166503 18267061 18465289 18502740 18516705 18517394 18603551 18612114 18626449 18629807 18821617 18838339 18897433 18950698 19614652 19636187 19660665 19686665 19780854 19859562 19920619 20014564 20704691 20804434 21084676 21111939 21211234 21513264 21877948 21985283 22237894 23150423 23225591 23579606 23871227 23908709 23942352 23976025 24317692 24331174 24495966 24496424 24500663 24529893 24766892 24766892 24820384 24820384 24995868 24995868 25025079 25053077 25121024 25152673 25213331 25235660 25536727 25536727 25536727 25574404 25574404 25574404 25715420 25806660 25806660 26238624 26252336 26352615 26367854 26443771 26445599 26446005 26678302 26788668 26849822

5.5 6 6.75 14 10.5 5 10 3.5 5.5 6 8.5 4.75 5 5 8.66667 3.83333 8 4.8 3.75 10 3 12 4.33333 6 5 4.4 7 9 9 4.75 7 3.75 5.25 3.5 10.5 3 3.5 4.66667 3.5 7.33333 3.75 5 5 5.66667 4 8 4.25 4.75 3.8 5 6.5 3.4 7.33333 6 6 5 5 3.75 3.75 8.5 5.5 10.5 3.2 3 3.75 3.6 3.6 3.6 4.66667 4.66667 4.66667 5.5 3.5 3.5 4.66667 6 8.5 5.66667 6.5 11.5 9 7.33333 9 6

. . . . . . . . . . . ENSSSCT00000018296 . . . ENSSSCT00000018300 ENSSSCT00000018300 ENSSSCT00000018300 ENSSSCT00000018300 . . ENSSSCT00000036642 ENSSSCT00000036642 . . . . . . . . . ENSSSCT00000018316 . ENSSSCT00000018317 ENSSSCT00000018317 ENSSSCT00000018324 . . ENSSSCT00000018326 . . ENSSSCT00000018340 ENSSSCT00000018344 ENSSSCT00000018344 ENSSSCT00000018344 ENSSSCT00000018344 . . . . . . ENSSSCT00000018347 ENSSSCT00000025413 ENSSSCT00000018347 ENSSSCT00000025413 ENSSSCT00000018350 ENSSSCT00000032662 . . . . . . ENSSSCT00000035208 ENSSSCT00000034777 ENSSSCT00000018355 ENSSSCT00000035208 ENSSSCT00000034777 ENSSSCT00000018355 . ENSSSCT00000018358 ENSSSCT00000018356 . . . . . . . . . .

. . . . . . . . . . . CDH6 . . . DROSHA DROSHA DROSHA DROSHA . . PDZD2 PDZD2 . . . . . . . . . C1QTNF3 . RAI14 RAI14 AGXT2 . . SPEF2 . . C5orf42 WDR70 WDR70 WDR70 WDR70 . . . . . . EGFLAM EGFLAM EGFLAM EGFLAM LIFR LIFR . . . . . . FYB FYB FYB FYB FYB FYB . DAB2 C9 . . . . . . . . . .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intron intron intron intron intergenic intergenic promoter intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intron intron intron intergenic intergenic intron intergenic intergenic intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

. -0.021 0.596 . . 0.446 0.117 1.177 0.442 0.456 -0.127 0.247 0.244 0.605 . 0.273 -0.027 0.448 -0.366 0.246 0.468 -0.043 -0.039 0.178 -0.088 -0.037 . 0.443 . 0.13 0.135 -0.016 . 0.155 0.091 0.328 0.185 . 0.018 0.969 -0.164 . -0.001 . . 1.291 0.054 0.124 . 0.22 . 0.048 0.211 . . 0.154 0.154 0.181 0.181 -0.007 0.155 . 0.5 0.174 . 0.109 0.109 0.109 0.046 0.046 0.046 -0.113 -0.008 -0.008 . 0.106 -0.034 -0.136 . . . . 0.283 0.231

rs790562349 rs790894768 508306 rs7929 rs787061964 rs792826900 rs791059323 . . 279657 rs7863 rs790325528 498395 rs7917 rs790093154 rs789561482 . 678406 rs7900 731492 rs7892 rs793370252 965002 rs7865 rs691675883 157614 rs7900 rs787727109 . 579384 rs7928 072374 rs7932 rs791181243 445122 rs7927 rs707813158 rs787883173 rs789737210 rs793464995 550242 rs7912 . 509609 rs7889 rs788469333 . rs789219534 rs789166224 528267 rs7872 rs793584891 rs790589017 rs793428185 rs792799745 141177 rs7869 rs790453810 . . 192236 rs7906 rs792130954 709307 rs7872 811272 rs7904 rs788035572 rs788695615 333528 rs7908 . . rs789135926 rs789135926 rs792126472 rs792126472 . rs786916581 rs789541391 rs793590188 rs789875026 rs789565836 rs787475423 rs787475423 rs787475423 rs789457418 rs789457418 rs789457418 rs793488902 rs787833475 rs787833475 rs790022787 rs790060954 rs791441226 rs793205168 rs789532540 rs788774087 rs793053962 335676 rs7926 rs790804961 .

3 2 2 2 2 3 3 2 2 2 3 2 2 3 2 2 2 2 2 3 2 4 2 2 3 2 3 2 2 2 2 2 3 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 4 3 2 2 2 5

AAAT.ATTT AAAT.ATTT AG.CT AT.AT AAAC.GTTT AAAC.GTTT AT.AT AC.GT AAAAT.ATTTT AG.CT AAAC.GTTT AC.GT AAAT.ATTT AAT.ATT AG.CT AG.CT AAAC.GTTT AAAT.ATTT AAAAC.GTTTT AT.AT AC.GT AAAC.GTTT AC.GT AAAC.GTTT AAAC.GTTT AT.AT AAAT.ATTT AAT.ATT AC.GT AC.GT AAC.GTT AG.CT AT.AT AAAT.ATTT AAAC.GTTT AG.CT AG.CT AACC.GGTT AAAC.GTTT AG.CT AC.GT AG.CT AAAC.GTTT AGAT.ATCT AT.AT AT.AT AT.AT AAAG.CTTT AC.GT AC.GT AC.GT AC.GT AG.CT AAAC.GTTT AAAAG.CTTTT AAAAC.GTTTT ATC.GAT AAAAG.CTTTT AC.GT AAAT.ATTT AT.AT AC.GT AC.GT AGAT.ATCT AAGG.CCTT AAGG.CCTT ACT.AGT ACT.AGT AAC.GTT AC.GT AC.GT AC.GT AC.GT AC.GT AT.AT AAAAC.GTTTT AG.CT AT.AT AC.GT AAAT.ATTT AAAT.ATTT AAAC.GTTT AAAT.ATTT AC.GT

16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16

26859213 26888977 27033399 27035767 27138131 27228777 27230782 27250252 27558048 28242644 28338782 28548458 28571813 28759127 29099330 29333050 29341318 29451833 29504440 29600337 30210703 30228517 30311679 30435135 30437276 30806863 30918190 30945206 30964932 30975055 31083739 31105392 31129438 31228083 31354939 31365002 31389903 31597888 31651389 32088067 32098297 32140209 32157384 32158737 32421481 32432158 32436354 32439502 32542631 32632649 32652228 32678565 32705012 32763489 32996006 33207893 33307300 33322649 33411651 33661089 33662799 33768908 33779370 33903670 34023827 34023827 34112120 34112120 34152255 34197222 34197222 34197222 34197222 34197222 34269848 34476738 34493730 34675497 34878262 34907246 34931032 35016657 35022842 35315651

26859232 26889002 27033408 27035778 27138153 27228797 27230792 27250264 27558067 28242654 28338799 28548470 28571829 28759153 29099344 29333059 29341336 29451852 29504479 29600347 30210713 30228529 30311689 30435149 30437301 30806873 30918216 30945226 30964954 30975078 31083756 31105403 31129452 31228106 31354950 31365015 31389914 31597913 31651408 32088083 32098308 32140223 32157403 32158764 32421499 32432169 32436365 32439516 32542651 32632658 32652239 32678577 32705025 32763515 32996020 33207909 33307331 33322675 33411665 33661102 33662809 33768929 33779384 33903686 34023852 34023852 34112140 34112140 34152266 34197235 34197235 34197235 34197235 34197235 34269860 34476760 34493740 34675521 34878283 34907273 34931046 35016679 35022861 35315663

5 6.5 5 6 5.75 5.25 5.5 6.5 4 5.5 4.5 6.5 4.25 9 7.5 5 4.75 5 8 5.5 5.5 3.25 5.5 3.75 6.5 5.5 6.75 7 11.5 12 6 6 7.5 6 3 7 6 6.5 5 8.5 6 7.5 5 7 9.5 6 6 3.75 10.5 5 6 6.5 7 6.75 3 3.4 10.6667 5.4 7.5 3.5 5.5 11 7.5 4.25 6.5 6.5 7 7 4 7 7 7 7 7 6.5 4.6 5.5 12.5 11 7 3.75 5.75 5 6.5

ENSSSCT00000030818 . intron . . intergenic ENSSSCT00000023181 MROH2B intron ENSSSCT00000023181 MROH2B intron ENSSSCT00000018362 . intron ENSSSCT00000018364 C6 intron ENSSSCT00000018364 C6 intron ENSSSCT00000018364 C6 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000018369 GHR intron . . intergenic ENSSSCT00000018373 . promoter . . intergenic ENSSSCT00000018376 HMGCS1 3'utr ENSSSCT00000018377 NIM1K intron ENSSSCT00000018378 PAIP1 intron . . intergenic . . intergenic ENSSSCT00000018382 FGF10 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000028722 HCN1 intron ENSSSCT00000028722 HCN1 intron ENSSSCT00000028722 HCN1 intron ENSSSCT00000028722 HCN1 intron ENSSSCT00000028722 HCN1 intron ENSSSCT00000028722 HCN1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000018389 ITGA1 intron ENSSSCT00000034458 ITGA1 intron ENSSSCT00000018389 ITGA1 intron ENSSSCT00000033593 ITGA1 intron . . intergenic ENSSSCT00000032891 ITGA2 intron ENSSSCT00000035637 ITGA2 intron ENSSSCT00000034283 ITGA2 intron ENSSSCT00000018391 ITGA2 intron ENSSSCT00000032880 ITGA2 intron ENSSSCT00000018392 MOCS2 3'utr . . intergenic . . intergenic . . intergenic ENSSSCT00000022508 . intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000018399 ARL15 intron

. . 0.021 -0.229 -0.196 0.029 -0.097 -0.022 . . 0.022 -0.147 . 0.079 0.134 0.081 -0.368 1.139 0.177 1.272 0.262 0.034 0.789 0.106 0.198 . 0.023 . 0.167 0.316 -0.191 0.068 0.124 0.139 . -0.12 0.642 . -0.375 -0.084 0.111 -0.137 0.063 -0.08 . . -0.039 0.124 0.151 0.312 -0.04 -0.29 -0.025 . -0.017 -0.094 -0.29 -0.042 0.083 . -0.139 0.02 . 0.227 0.183 0.183 0.243 0.243 . 0.143 0.143 0.143 0.143 0.143 . -0.059 . . . 0.271 . . . -0.079

rs791637780 337112 rs7876 rs790070622 . 798224 rs7884 rs788644770 rs791565635 . rs706610362 . 560701 rs7896 . rs793029235 . rs793633251 rs791278182 rs788706179 702505 rs7935 323677 rs7102 812238 rs7936 . 775002 rs7862 . rs790430303 . rs792731234 058818 rs7887 777361 rs7907 . rs792855461 . . 769755 rs7915 rs788651400 rs786327758 rs791691776 . . 434160 rs7890 . rs788111302 rs792735470 227689 rs7933 rs788724500 757964 rs7908 rs695560861 . 632079 rs7896 rs792394207 . . rs792770393 852236 rs7893 260079 rs7906 rs786854793 rs786905410 rs710280074 151070 rs7901 rs693440515 rs790725255 rs788129476 rs789878802 . rs787961021 530618 rs7905 530618 rs7905 rs792793965 rs792793965 649487 rs7911 . . . . . rs791924036 rs790230002 . rs786429988 rs791833184 659899 rs7901 . rs786642917 rs789688739 .

2 2 2 3 2 2 2 4 2 3 3 2 2 2 3 3 2 2 2 2 3 2 3 2 3 2 2 2 2 3 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 3 3 2 3 3 2 2 3 2 2 2 3 2 4 2 2 3 2 2 2 2 2 2 2 3 3 3 3 3 3 2 2 2 2 2 2 2 2 3

AAG.CTT AG.CT AAAC.GTTT AAAT.ATTT AAAC.GTTT AGG.CCT AGGC.GCCT AT.AT AAAAAC.GTTTTT AC.GT AAAC.GTTT AAAC.GTTT AAAT.ATTT AAAAC.GTTTT AAAC.GTTT AGG.CCT AAAC.GTTT AAAC.GTTT AAC.GTT AAC.GTT AAAAC.GTTTT AC.GT AACT.AGTT AC.GT AG.CT AAT.ATT AG.CT AAC.GTT AG.CT AAATT.AATTT AAAAC.GTTTT AC.GT AT.AT AAAT.ATTT ACC.GGT AC.GT AGAT.ATCT AAAC.GTTT AC.GT AG.CT AT.AT AAAC.GTTT ACAT.ATGT AAAAC.GTTTT AC.GT ACAT.ATGT AAAT.ATTT AAAC.GTTT AAAT.ATTT AAAT.ATTT AAAC.GTTT AAC.GTT AAC.GTT AAAG.CTTT AAAAT.ATTTT AT.AT AC.GT AC.GT AC.GT AAC.GTT AT.AT AGC.GCT AT.AT AAAC.GTTT AAAT.ATTT AAAT.ATTT AC.GT AAAG.CTTT AAAC.GTTT AAAAC.GTTTT AC.GT AG.CT AAC.GTT AAAAAC.GTTTTT AAAC.GTTT AG.CT AT.AT AG.CT AAAC.GTTT AAAT.ATTT AAAG.CTTT AAAAG.CTTTT AG.CT AC.GT

16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16

35382833 35915730 36123484 36206763 36270203 36316766 36318579 36726073 37197569 37432742 37563651 37607016 37681305 37681581 37789562 37911927 38007221 38047317 38181710 38185206 38230417 38285858 38403591 38445891 38463684 38755356 38975037 38999929 39017580 39201745 39761818 39811567 40010242 40094741 40171625 40318757 40402632 40456442 40596832 40639099 40956133 40984210 40992875 41023670 41084018 41984597 42119389 42120343 42223443 42261897 42480627 42538958 42538958 42618079 42871390 43104787 43317840 43356573 43384484 43480494 43506965 43508680 43513619 43754923 43785052 43824890 44018765 44406519 44556840 45142716 45359435 45727702 45737366 45802341 46037801 46166740 46326495 46390113 46403295 46592525 46746600 46813099 46929006 47153045

35382844 35915750 36123502 36206785 36270239 36316798 36318596 36726084 37197594 37432756 37563674 37607034 37681320 37681601 37789577 37911943 38007234 38047331 38181726 38185229 38230440 38285873 38403608 38445901 38463693 38755378 38975046 38999944 39017592 39201763 39761837 39811579 40010251 40094763 40171645 40318769 40402651 40456464 40596842 40639133 40956142 40984232 40992893 41023698 41084028 41984615 42119412 42120365 42223456 42261914 42480646 42538974 42538974 42618113 42871417 43104797 43317852 43356588 43384494 43480518 43506992 43508693 43513640 43754945 43785074 43824911 44018774 44406537 44556863 45142738 45359449 45727714 45737391 45802364 46037833 46166751 46326509 46390131 46403320 46592540 46746619 46813115 46929021 47153062

4 10.5 4.75 5.75 9.25 11 4.5 6 4.33333 7.5 6 4.75 4 4.2 4 5.66667 3.5 3.75 5.66667 8 4.8 8 4.5 5.5 5 7.66667 5 5.33333 6.5 3.8 4 6.5 5 5.75 7 6.5 5 5.75 5.5 17.5 5 5.75 4.75 5.8 5.5 4.75 6 5.75 3.5 4.5 5 5.66667 5.66667 8.75 5.6 5.5 6.5 8 5.5 8.33333 14 4.66667 11 5.75 5.75 5.5 5 4.75 6 4.6 7.5 6.5 8.66667 4 8.25 6 7.5 9.5 6.5 4 5 3.4 8 9

ENSSSCT00000018399 . . . . . . ENSSSCT00000018418 . . ENSSSCT00000018421 ENSSSCT00000018421 . . ENSSSCT00000020475 . . . ENSSSCT00000018424 ENSSSCT00000018424 . ENSSSCT00000018427 . . . . . . . . . . . . ENSSSCT00000018434 ENSSSCT00000018435 ENSSSCT00000018435 ENSSSCT00000018435 . ENSSSCT00000018436 ENSSSCT00000029920 . . . . . . . . . . ENSSSCT00000018441 ENSSSCT00000018440 ENSSSCT00000018442 ENSSSCT00000025662 . . . . . . . . . . . . . . . . . . ENSSSCT00000018449 . . . . . ENSSSCT00000018450 ENSSSCT00000018450 ENSSSCT00000018450 . ENSSSCT00000018451

ARL15 . . . . . . PPAP2A . . IL31RA IL31RA . . U6 . . . MAP3K1 MAP3K1 . MIER3 . . . . . . . . . . . . . RAB3C RAB3C RAB3C . PDE4D . . . . . . . . . . . ELOVL7 ELOVL7 ERCC8 NDUFAF2 . . . . . . . . . . . . . . . . . . RNF180 . . . . . CWC27 CWC27 CWC27 . ADAMTS6

intron intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intron intron intergenic intergenic promoter intergenic intergenic intergenic intron intron intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic promoter intron intron intron intergenic 3'utr intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intron

. 0.02 0 . 0.052 -0.024 0.602 0.091 0.108 0.197 -0.119 -0.016 . . . . 0.103 . 0.222 1.659 . 0.417 -0.157 . 0.134 0.187 . . 0.157 . 0.17 0.023 0.089 . . 0.066 -0.048 . 0.087 1.597 . 0.002 -0.084 . -0.127 . . . 0.018 -0.111 0.092 0.241 0.241 . . 0.384 . -0.033 . 0.166 0.044 0.014 0.449 0.182 -0.045 0.13 0.171 0.458 0.074 0.081 0.069 -0.01 . . . . 0.168 . . 1.867 . -0.474 0.116 0.091

rs789556478 rs791749427 rs789688246 rs789736979 rs793420355 370940 rs7923 rs787936554 098878 rs7897 745519 rs7927 rs793226919 722277 rs7889 rs787361628 340741 rs7914 . 749275 rs7900 rs789178893 rs786312620 rs697025129 . 795942 rs7933 rs787308020 654626 rs7871 rs788635949 rs793376879 rs788830227 349547 rs7901 rs788710500 . . 516544 rs7937 rs793352532 906967 rs7934 rs789778091 rs789102943 014301 rs7904 rs790452408 925220 rs7908 546163 rs7868 rs788893488 rs789767444 rs791369265 rs787186622 . 255236 rs7933 rs789335980 . 223252 rs7902 rs793146268 . rs787201452 261775 rs7867 264539 rs7910 264539 rs7910 . rs788783623 . rs789457391 rs792409759 rs787369148 rs789928851 . rs791293949 rs786538720 rs790084382 . rs793326782 rs788669519 969099 rs7879 rs792603949 . rs791318897 rs702123902 rs786306000 rs788086072 rs787148390 rs793234682 . rs792981997 rs789658714 . rs786832153 rs790408024 . rs791325048

2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 5 2 2 3 2 3 2 2 2 2 2 2 2 3 2 3 2 2 2 2 4 2 2 2 2 2 2 2 2 3 2 2 2 2 4 2 2 2 2 2 2 2

AC.GT AC.GT AT.AT AAG.CTT AC.GT AG.CT AT.AT ACAT.ATGT AC.GT AAT.ATT ATC.GAT AAAAT.ATTTT AAAAT.ATTTT AAAAT.ATTTT AAAAT.ATTTT ACAGC.GCTGT AAC.GTT AC.GT AG.CT AAAAAC.GTTTTT AC.GT AT.AT AT.AT AAAC.GTTT AC.GT AC.GT AAAAG.CTTTT AAAG.CTTT AATG.CATT AG.CT AC.GT AAC.GTT AATG.CATT AC.GT AAAT.ATTT AAAAC.GTTTT AG.CT AACT.AGTT AC.GT AAAAC.GTTTT AAAAT.ATTTT AG.CT AAAAC.GTTTT AAAAT.ATTTT AAAAC.GTTTT AAT.ATT AATG.CATT AT.AT ACC.GGT AAAT.ATTT AAAATT.AATTTT AC.GT AAAG.CTTT AAAAT.ATTTT AC.GT AG.CT AG.CT AG.CT AAAG.CTTT AAT.ATT AG.CT AG.CT AAAAG.CTTTT AC.GT AG.CT AGGGG.CCCCT AC.GT AAAAT.ATTTT ACACT.AGTGT AAAC.GTTT AAAT.ATTT AG.CT AAAAAC.GTTTTT AG.CT AAAT.ATTT AAAAT.ATTTT AAAG.CTTT AG.CT AC.GT AC.GT AAAAC.GTTTT AACT.AGTT AAAC.GTTT AG.CT

16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16

47841009 48013672 48117708 48414825 49015565 49191912 49480419 49544476 49795505 49821209 49878566 50380838 50380838 50380838 50380838 50671100 50750983 50799990 50851774 50940917 51246153 51395383 51395383 51541514 51875887 51875887 52178136 52209258 52260135 52605516 52674375 52852828 52853914 52899421 52974307 53285673 53548780 53694555 54102448 54713474 54795857 54906245 55249413 55382996 55721037 56114033 56121572 56284299 56423728 56427778 56591943 57163973 57166645 57543718 57847677 57861391 57953192 58030462 58031659 58450072 58581663 58972300 59203121 59426188 59525810 59704195 59898680 59926308 60105986 60109981 60120304 60574555 60596692 60633891 60739738 60758045 60930130 60975992 61000035 61029740 61074904 61112473 61134109 61242758

47841021 48013684 48117721 48414845 49015577 49191921 49480431 49544500 49795517 49821234 49878593 50380862 50380862 50380862 50380862 50671114 50751005 50800002 50851786 50940941 51246169 51395394 51395394 51541536 51875899 51875899 52178153 52209269 52260161 52605527 52674393 52852841 52853928 52899432 52974332 53285691 53548790 53694576 54102458 54713503 54795878 54906270 55249431 55383014 55721059 56114049 56121600 56284309 56423750 56427808 56591965 57163988 57166669 57543751 57847695 57861418 57953214 58030481 58031678 58450086 58581693 58972316 59203149 59426200 59525824 59704210 59898692 59926334 60106005 60109992 60120324 60574570 60596715 60633905 60739753 60758071 60930148 60976010 61000049 61029752 61074927 61112486 61134127 61242774

6.5 6.5 7 7 6.5 5 6.5 6.25 6.5 8.66667 9.33333 5 5 5 5 3 7.66667 6.5 6.5 4.16667 8.5 6 6 5.75 6.5 6.5 3.6 3 6.75 6 9.5 4.66667 3.75 6 6.5 3.8 5.5 5.5 5.5 6 4.4 13 3.8 3.8 4.6 5.66667 7.25 5.5 7.66667 7.75 3.83333 8 6.25 6.8 9.5 14 11.5 10 5 5 15.5 8.5 5.8 6.5 7.5 3.2 6.5 5.4 4 3 5.25 8 4 7.5 4 5.4 4.75 9.5 7.5 6.5 4.8 3.5 4.75 8.5

ENSSSCT00000018461 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000035672 PIK3R1 promoter ENSSSCT00000036318 PIK3R1 promoter ENSSSCT00000033449 PIK3R1 promoter ENSSSCT00000035520 PIK3R1 promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000026613 CENPH promoter ENSSSCT00000018473 . intron ENSSSCT00000030315 . intron . . intergenic ENSSSCT00000018480 . intron ENSSSCT00000026987 . intron . . intergenic . . intergenic . . intergenic ENSSSCT00000018485 PTCD2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000026046 TNPO1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000018507 . intron ENSSSCT00000032458 FBXW11 intron ENSSSCT00000018512 RANBP17 intron ENSSSCT00000018512 RANBP17 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000018524 SLIT3 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

0.217 . 0.154 0.148 0.021 -0.036 0.285 -0.009 0.054 0.104 -0.164 . . . . 0.118 . 0.318 -0.116 0.425 . 0.153 0.153 -0.07 0.061 0.061 . 0.247 -0.251 -0.024 -0.043 0.087 -0.031 0.769 0.269 0.023 -0.091 0.193 . . . 0.284 . -0.145 -0.044 -0.153 -0.264 0.222 0.111 0.801 . . . 0.105 -0.044 -0.125 -0.242 -0.075 . 0.082 0.618 0.036 0.986 -0.049 -0.168 0.051 0.143 0.141 -0.308 -0.129 -0.146 0.047 0.015 0.029 0.005 0.116 0.023 0.35 0.986 -0.412 1.001 0.315 0.717 0.353

rs787174159 rs790226252 374409 rs7882 rs792489384 rs788837988 rs788487689 815188 rs7878 910779 rs7866 rs789722624 rs791275763 rs788104531 rs791402474 rs791402474 rs791402474 rs791402474 rs787574372 rs787778303 rs792910277 . rs694182392 rs786427825 rs793654442 rs793654442 . . . rs786947480 rs786627297 rs706461025 . rs792495326 rs789066109 . . rs789581493 rs787348048 rs787397626 rs789959912 rs789740992 rs787237117 rs791038902 rs791926899 rs792896158 rs790463738 826015 rs7909 746318 rs7897 rs787813209 rs791970621 rs787628462 762764 rs7889 rs787021002 . rs790413113 346114 rs7029 rs789915821 788994 rs7905 rs790887361 rs789804324 . rs790212612 rs792354367 rs791724581 . . . rs792112862 . 193959 rs7906 rs793259632 rs792479999 rs786478018 975271 rs7883 rs793037577 rs791566543 991546 rs7874 rs789512268 rs789687953 . rs787090999 . rs787462637 rs787728073 rs790045943 .

2 9 4 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 3 2 2 2 2 3 3 2 3 2 2 4 2 4 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 3 3

AAAAG.CTTTT AAAAC.GTTTT AAC.GTT AC.GT AAAAC.GTTTT AG.CT AG.CT ACAG.CTGT AC.GT AG.CT AAAT.ATTT AAAT.ATTT AAAT.ATTT AC.GT AAAT.ATTT AAAAC.GTTTT AAAC.GTTT AAAT.ATTT AAAC.GTTT AAAC.GTTT AC.GT AAC.GTT AG.CT AAC.GTT AG.CT AAC.GTT AAAAC.GTTTT AAAGT.ACTTT AG.CT AC.GT AG.CT AC.GT AT.AT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AAAC.GTTT AC.GT AT.AT AT.AT AC.GT AATG.CATT AC.GT AT.AT AT.AT AAAT.ATTT AT.AT AC.GT AC.GT AT.AT AAAT.ATTT AT.AT AAAC.GTTT AG.CT ACC.GGT AT.AT AC.GT AC.GT AT.AT AAT.ATT AAAC.GTTT AC.GT AG.CT AC.GT AG.CT AAC.GTT AAAAC.GTTTT AT.AT AT.AT AC.GT AAAC.GTTT AATG.CATT AAAT.ATTT AAAT.ATTT AC.GT AAAC.GTTT AC.GT AC.GT AG.CT AAC.GTT AT.AT AAAAC.GTTTT

16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16

61566075 61904208 61910716 61973932 62183786 62681226 62686327 62813120 62906703 62915138 63225016 63273181 63292920 63313183 63314007 63357809 63585451 63605796 63660557 63805391 63824218 64150302 64386764 64407250 64458972 64520285 64694487 64752734 64778069 64822010 64992500 64993805 65053959 65145044 65145044 65145044 65145044 65263601 65451465 65639527 65956972 66020579 66083607 66109737 66237578 66429147 66957074 67280289 67344955 67368567 67397880 67766845 68339182 68517534 68663138 68673739 68718068 68767227 68925531 69076070 69865985 70127727 70299390 70400660 70606464 70618023 70650590 70706779 70833339 70834474 70845700 70910605 71044189 71063513 71167684 71264879 71433102 71458734 71546847 71687548 71722889 71945179 71950738 72260337

61566093 61904225 61910729 61973946 62183803 62681241 62686337 62813135 62906721 62915147 63225052 63273200 63292949 63313194 63314032 63357829 63585465 63605818 63660582 63805414 63824240 64150319 64386774 64407262 64458981 64520301 64694512 64752748 64778078 64822020 64992513 64993817 65053970 65145058 65145058 65145058 65145058 65263623 65451483 65639537 65956982 66020588 66083618 66109755 66237593 66429157 66957086 67280305 67344966 67368576 67397895 67766856 68339197 68517544 68663156 68673755 68718082 68767238 68925545 69076084 69866000 70127739 70299404 70400675 70606475 70618042 70650600 70706793 70833365 70834483 70845713 70910615 71044221 71063531 71167706 71264919 71433112 71458756 71546859 71687557 71722903 71945200 71950749 72260361

3.8 3.6 4.66667 7.5 3.6 8 5.5 4 9.5 5 9.25 5 7.5 6 6.5 4.2 3.75 5.75 6.5 6 11.5 6 5.5 4.33333 5 5.66667 5.2 3 5 5.5 7 6.5 6 3.75 3.75 3.75 3.75 4.6 4.75 5.5 5.5 5 6 4.75 8 5.5 6.5 4.25 6 5 8 6 4 5.5 4.75 8.5 5 6 7.5 7.5 8 4.33333 3.75 8 6 10 5.5 5 5.4 5 7 5.5 8.25 4.75 5.75 10.25 5.5 5.75 6.5 5 7.5 7.33333 6 5

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000034673 HMMR intron ENSSSCT00000018534 HMMR intron ENSSSCT00000036191 HMMR intron ENSSSCT00000030611 HMMR intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000018554 ADRA1B intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000018562 THG1L intron . . intergenic . . intergenic ENSSSCT00000018567 CYFIP2 intron . . intergenic ENSSSCT00000018576 HAVCR1 intron . . intergenic

-0.032 -0.185 0.694 -0.159 . 0.37 0.455 0.188 0.081 0.086 -0.169 . -0.049 -0.205 -0.241 . . -0.066 -0.229 -0.092 0.259 0.122 0.586 . 0.018 0.15 0.269 0.117 -0.095 0.151 0.922 0.234 0.152 . . . . 0.127 0.181 0.047 . -0.12 0.043 -0.128 . 0.163 -0.07 0.076 0.033 -0.248 0.037 0.037 0.023 0.242 0.146 0.094 0.099 -0.072 1.573 0.254 0.085 0.118 0.109 0.559 -0.027 -0.013 0.021 0.415 -0.031 0.029 0.079 0.056 . 0.021 0.294 . 0.172 0.135 0.092 -0.059 1.493 . -0.13 0.044

rs700662049 . 532251 rs7919 392085 rs7888 184795 rs7870 . rs787288146 . rs786812457 . . rs697865892 806930 rs7936 . rs791812747 . 895138 rs7881 145204 rs7881 568200 rs7870 rs790472393 044640 rs7889 768292 rs7885 204157 rs7924 rs786211821 . rs791495722 rs789424372 . rs787059129 rs791118681 . 436015 rs7894 . rs789677182 rs789677182 rs789677182 rs789677182 249353 rs7906 343338 rs7909 969737 rs7919 rs793851362 . rs703968674 771447 rs7872 rs787202654 rs790197522 248801 rs7866 rs792619129 rs793829471 rs693100085 253017 rs7932 096381 rs7938 rs789791920 . rs792483906 rs788806629 . . 779955 rs7934 rs787729948 . 615916 rs7866 071784 rs7913 983736 rs7928 533159 rs7925 rs787530618 rs788956908 rs788387433 142578 rs7921 rs789006462 369714 rs7910 rs788819814 673034 rs7910 rs786225650 rs791025266 rs786738689 rs791009551 969343 rs7896 . . rs790650791 rs788568997 rs789231859 rs790133190

4 2 2 3 2 2 2 2 3 2 2 2 2 3 2 2 2 2 2 2 4 3 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 3 2 2 4 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 3 2 2 2 2 4 2 2 2 2 3 3 3 2 2 2 2 2 2 2 4 2 2 2 2

AGAT.ATCT AT.AT AAC.GTT AAG.CTT AT.AT AAAAC.GTTTT ATC.GAT AAAAAC.GTTTTT AAAC.GTTT AAAC.GTTT AG.CT AAT.ATT AAAT.ATTT AAAT.ATTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAT.ATTT AC.GT AG.CT AT.AT AT.AT AAAAAC.GTTTTT AAC.GTT AC.GT AT.AT AAAT.ATTT AAT.ATT AAC.GTT AGAT.ATCT AT.AT AATT.AATT AC.GT AAAC.GTTT AC.GT ACAT.ATGT AAT.ATT AAAT.ATTT AT.AT AC.GT AT.AT AC.GT AAAAAC.GTTTTT AAAC.GTTT AC.GT AAAC.GTTT AAAC.GTTT ACAT.ATGT AC.GT AT.AT AC.GT AC.GT AAG.CTT AAAC.GTTT AAGAC.GTCTT AAC.GTT AAAG.CTTT AC.GT AT.AT AC.GT AAAT.ATTT AGC.GCT AGG.CCT AG.CT AAT.ATT AG.CT AAC.GTT AAGGG.CCCTT AAAAG.CTTTT AC.GT AAAC.GTTT AAT.ATT AAAT.ATTT AAAC.GTTT AAAAC.GTTTT AG.CT AAAACC.GGTTTT AC.GT AG.CT AG.CT AC.GT AC.GT AAT.ATT AAAC.GTTT

16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16 16

72773644 73036396 73333651 73366574 73478640 73554207 73605230 73913950 73940066 73952698 73962610 74062698 74165432 74260656 74296308 74394116 74711332 74876438 74934137 74966939 75309652 75393558 75507285 75615655 75619258 75692800 75732417 75804413 75828822 75838282 75963045 76084440 76096776 76188743 76241774 76386781 76392162 76396315 76932779 77065024 77262484 77324535 77371546 77651764 77731596 77883067 78594134 78601934 79178910 79445193 79609721 79624728 79693488 79749999 79888736 79897177 79920543 80020816 80144211 80173267 80207744 80493117 80696944 80946680 80953271 81238760 81260379 81443850 81678987 81828910 81859651 82034658 82087345 82159887 82174059 82193716 82691913 83291951 83349160 83699640 84227837 84734158 85266104 85788108

72773655 73036405 73333682 73366592 73478653 73554237 73605242 73913971 73940085 73952734 73962619 74062715 74165450 74260678 74296330 74394131 74711364 74876462 74934157 74966951 75309666 75393583 75507325 75615671 75619268 75692810 75732435 75804437 75828835 75838299 75963063 76084459 76096790 76188772 76241788 76386797 76392175 76396330 76932789 77065039 77262498 77324544 77371563 77651782 77731626 77883090 78594148 78601952 79178919 79445209 79609735 79624741 79693503 79750013 79888755 79897191 79920557 80020827 80144220 80173283 80207763 80493132 80696956 80946713 80953290 81238773 81260401 81443872 81679007 81828925 81859677 82034682 82087359 82159909 82174083 82193734 82691936 83291965 83349183 83699666 84227856 84734167 85266121 85788127

3 5 10.6667 6.33333 7 6.2 4.33333 3.66667 5 9.25 5 6 4.75 5.75 5.75 4 8.25 6.25 10.5 6.5 7.5 13 6.83333 5.66667 5.5 5.5 4.75 8.33333 4.66667 4.5 9.5 5 7.5 7.5 7.5 4.25 4.66667 4 5.5 8 7.5 5 3 4.75 15.5 6 3.75 4.75 5 8.5 7.5 7 5.33333 3.75 4 5 3.75 6 5 8.5 5 5.33333 4.33333 17 6.66667 7 7.66667 4.6 4.2 8 6.75 8.33333 3.75 5.75 5 9.5 4 7.5 12 13.5 10 5 6 5

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000026183 . intron ENSSSCT00000018582 CNOT8 intron ENSSSCT00000018583 FAXDC2 intron . . intergenic ENSSSCT00000018588 GALNT10 intron ENSSSCT00000018588 GALNT10 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000021150 SNORA18 promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000018594 GLRA1 intron . . intergenic ENSSSCT00000018600 FAT2 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000018613 SEMA5A intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000018619 ADCY2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000018621 SRD5A1 intron ENSSSCT00000018623 UBE2QL1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000018627 ADAMTS16 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

. 0.032 . 0.056 0.005 0.108 0.238 . 0.283 0.005 -0.118 0.159 0.18 . . 0.111 0.209 0.014 0.438 0.238 0.135 -0.024 0.426 0.176 0.076 0.028 -0.01 -0.028 0.146 -0.058 -0.105 -0.089 -0.142 . 0.006 . -0.014 -0.061 . 0.205 . 0.374 . -0.326 0.161 . . . -0.27 . -0.116 . -0.38 -0.135 -0.09 . . -0.268 -0.077 -0.045 0.065 . -0.245 . -0.166 . -0.186 0.233 -0.585 -0.421 -0.51 . 0.093 -0.153 -0.105 -0.482 -0.264 -0.451 -0.27 -0.29 . -0.09 . -0.257

. . rs793626055 . 987625 rs7933 rs789221666 . 852656 rs7898 909540 rs7905 532834 rs7864 rs787889595 827344 rs7876 rs793066133 rs793762889 rs788153875 rs789208972 048898 rs7913 rs793756355 . . rs788723784 rs690440782 738271 rs7878 rs793655493 rs788354724 447992 rs7910 941814 rs7932 rs787607577 rs789767581 576963 rs7870 . rs791625241 485898 rs7899 914691 rs7906 rs792015599 rs793864195 rs788860150 rs791252130 rs786756811 149560 rs7906 rs791204095 rs786236392 . rs793084259 . rs792705437 rs792698270 rs790360427 . rs786567053 . rs792698911 . rs792238405 rs787123363 476360 rs7864 rs787290795 rs787175608 rs786425524 rs787874089 rs787381802 rs787673946 . 351788 rs7889 . . rs790707918 rs787169989 828279 rs7869 . rs791000701 rs793740434 rs793194155 rs788768092 . 434434 rs7885 rs787387215 . rs792231064 rs793298740 508503 rs7900 . . 668603 rs7887

2 2 2 2 2 2 4 3 2 2 3 2 2 2 2 2 2 2 3 2 2 3 3 2 2 3 2 2 2 2 4 2 4 2 2 2 2 2 3 2 3 2 2 2 2 2 3 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 4 3 2 2 2 3 2 2 2 2 2 2 2 2 4 2 2 2 2 2

AAT.ATT AG.CT AAAAAC.GTTTTT AAAAAC.GTTTTT AAG.CTT AG.CT AT.AT AAAC.GTTT AAT.ATT AAAAC.GTTTT AAC.GTT AT.AT ATC.GAT AAAT.ATTT AG.CT AAAAC.GTTTT AC.GT AAT.ATT ACATAT.ATATGT AAAAT.ATTTT AG.CT AAC.GTT AG.CT AG.CT AT.AT AAC.GTT AAT.ATT AAAT.ATTT AT.AT AAAC.GTTT AT.AT AT.AT AT.AT AT.AT AC.GT AC.GT AAAT.ATTT AAGG.CCTT AAT.ATT AT.AT AAC.GTT ACAT.ATGT AAAC.GTTT AAGG.CCTT AAAT.ATTT AT.AT AT.AT AT.AT AC.GT AATG.CATT AAAC.GTTT AAAAC.GTTTT AC.GT AAAT.ATTT AC.GT AG.CT AAT.ATT AAC.GTT AAT.ATT AAC.GTT AAC.GTT AC.GT AAAAT.ATTTT AAAGC.GCTTT AGGG.CCCT AC.GT AAAC.GTTT AAAT.ATTT AAAC.GTTT AAAT.ATTT AT.AT AAAC.GTTT AT.AT AAAC.GTTT AC.GT AC.GT AAC.GTT AAAC.GTTT AC.GT AC.GT AAC.GTT AGAT.ATCT AG.CT AC.GT

16 16 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17

86546615 86853391 410948 776357 1087904 1148957 1171631 1614436 1839436 2430649 2433069 2476590 2534112 2572467 2622999 2857413 3117784 3320889 3517170 3537020 3737199 3766912 4089654 4275652 4325482 4395792 4539656 4588053 4888807 5136047 5193862 5417610 5591003 5711924 6020488 6405934 6580001 6991220 7077236 7143965 7159874 7168722 7256989 7317535 7361464 7373933 7789677 7894309 7909068 7910126 8121401 8175766 8250508 8349009 8380256 8530334 8598186 8656043 8723373 8801790 8912581 9048320 9079126 9083356 9268602 9338689 9414627 9509278 9520237 9734117 9789948 9791530 9941822 9942079 10234842 10400218 10939271 10989167 11041659 11230009 11363824 11416126 11604167 11897442

86546642 86853410 410975 776374 1087917 1148967 1171640 1614455 1839447 2430678 2433082 2476606 2534126 2572486 2623016 2857434 3117797 3320900 3517187 3537041 3737211 3766928 4089664 4275663 4325495 4395806 4539678 4588074 4888816 5136061 5193881 5417621 5591013 5711936 6020502 6405948 6580026 6991240 7077262 7143976 7159893 7168739 7257005 7317552 7361477 7373943 7789689 7894321 7909082 7910145 8121420 8175795 8250518 8349033 8380265 8530352 8598204 8656056 8723403 8801805 8912597 9048331 9079146 9083384 9268621 9338715 9414645 9509296 9520255 9734140 9789958 9791548 9941833 9942093 10234854 10400230 10939292 10989189 11041668 11230031 11363841 11416149 11604177 11897453

9.33333 10 4.66667 3 4.66667 5.5 5 5 4 6 4.66667 8.5 5 5 9 4.4 7 4 3 4.4 6.5 5.66667 5.5 6 7 5 7.66667 5.5 5 3.75 10 6 5.5 6.5 7.5 7.5 6.5 5.25 9 6 6.66667 4.5 4.25 4.5 3.5 5.5 6.5 6.5 7.5 5 5 6 5.5 6.25 5 9.5 6.33333 4.66667 10.3333 5.33333 5.66667 6 4.2 5.8 5 13.5 4.75 4.75 4.75 6 5.5 4.75 6 3.75 6.5 6.5 7.33333 5.75 5 11.5 6 6 5.5 6

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000031192 SGCZ intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000031844 TUSC3 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000007646 MICU3 intron ENSSSCT00000007646 MICU3 intron ENSSSCT00000007649 . intron . . intergenic ENSSSCT00000007652 . intron . . intergenic ENSSSCT00000007661 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000007666 FAT1 promoter ENSSSCT00000007666 FAT1 intron . . intergenic . . intergenic ENSSSCT00000007672 INTS10 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000007673 SGALNACT intron . . intergenic . . intergenic ENSSSCT00000007676 ADAM18 intron . . intergenic . . intergenic ENSSSCT00000007678 ZMAT4 intron . . intergenic . . intergenic . . intergenic

-0.27 -0.186 -0.142 0.68 -0.165 . 0.048 -0.013 . -0.101 -0.025 . 0.046 -0.007 -0.161 . 0.083 . . -0.228 0.016 . -0.204 . . -0.166 -0.041 0.037 0.031 . . 1.049 0.248 -0.069 0.023 . . . . . . 0.237 . . . . . . . . . . . . . . . . . . . . . . . . . . . -0.24 0.029 0.179 -0.184 . . . -0.66 . . -0.008 -0.088 0.075 -0.102 -0.073

rs791434716 . 208309 rs6936 886453 rs7901 rs693826640 . rs788697671 . . 869219 rs7885 375924 rs7929 . rs789138771 . 476980 rs7909 rs787276276 rs790589555 . rs786368690 664080 rs7915 . . 782682 rs7928 rs698293279 881288 rs7931 394112 rs7888 505946 rs7935 237210 rs7868 594941 rs7904 747829 rs7928 . 388839 rs7902 . rs709001361 rs786737891 371864 rs7884 469623 rs7875 . 513794 rs7924 . rs786736780 914324 rs7929 rs789230809 120908 rs7923 197230 rs7933 rs792105506 876900 rs7878 643339 rs7937 . rs787583452 . rs789424798 . . 689908 rs7873 813783 rs7916 rs789101481 rs788016126 rs788720855 rs792546362 rs788743123 rs792827543 . 627828 rs7904 rs791088945 rs790655778 543909 rs7862 . 767883 rs7875 rs712559077 rs787074125 rs788641660 947577 rs7887 rs788111480 . rs692722958 rs793594790 rs792802194 rs789193889 939977 rs7897 rs789292238 rs793052636 . rs789100991

2 2 2 2 2 2 4 3 2 2 2 3 2 2 2 2 2 2 2 2 4 2 2 4 2 2 3 2 3 2 2 2 3 3 2 2 2 2 2 3 4 2 2 2 2 2 2 2 3 2 2 3 3 2 3 4 2 2 2 2 2 2 2 2 2 3 2 2 3 2 3 2 2 2 2 3 2 2 2 3 2 2 2 2

AAAC.GTTT AAAG.CTTT AAAAAG.CTTTTT AG.CT ATCC.GGAT AC.GT AAG.CTT AT.AT AT.AT AC.GT AAAG.CTTT AG.CT AAC.GTT AAAAAG.CTTTTT AAAC.GTTT AAAT.ATTT AAAAG.CTTTT AG.CT AAAG.CTTT AAAT.ATTT AAAG.CTTT AG.CT AC.GT AAAT.ATTT AAAAAC.GTTTTT AT.AT AG.CT AAAC.GTTT AAAAC.GTTTT AG.CT AT.AT AAT.ATT AT.AT AG.CT AAAAT.ATTTT AT.AT AT.AT AAC.GTT AC.GT AAAT.ATTT AAAT.ATTT AC.GT AAAAAC.GTTTTT AAAC.GTTT AAAAC.GTTTT AC.GT AAAC.GTTT AAC.GTT AATC.GATT AAT.ATT AG.CT AAAT.ATTT AAAC.GTTT AT.AT AAC.GTT AC.GT AAG.CTT AAAAAG.CTTTTT AAT.ATT AGAT.ATCT AAAT.ATTT AAAT.ATTT AT.AT AC.GT AAGG.CCTT AT.AT AC.GT AC.GT AAAT.ATTT AAAG.CTTT AT.AT AAAAAT.ATTTTT ACAT.ATGT AG.CT AT.AT AAC.GTT ATC.GAT AC.GT AATC.GATT AAAC.GTTT AAC.GTT AAAC.GTTT AAAAC.GTTTT AC.GT

17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17

12035076 12075793 12171833 12249648 12310121 12732711 13059549 13434164 13475743 13478918 13642884 13789016 13838268 13930312 13946979 13975457 14146415 14148135 14173444 14217017 14252930 14525694 14569184 14625455 14647300 14656935 14796389 15029611 15238718 15314597 15411546 15416523 15420557 15444237 15446286 15502460 15502460 15550710 15776006 15933048 16455096 16891362 17436892 17474940 17665124 17784859 18124122 18128377 18467110 18864381 18882285 18944256 19009043 19021630 19055111 19059365 19117289 19171154 19196210 19280717 19728305 19735977 19843606 19907441 20423649 20496267 20708583 20716005 20781268 20824051 21014731 21329780 21487135 21500098 21502491 21518808 21519311 21566526 21592480 21683467 21694285 21725943 21733326 21958191

12035090 12075806 12171870 12249659 12310142 12732721 13059560 13434173 13475756 13478939 13642895 13789025 13838289 13930334 13946995 13975474 14146444 14148149 14173461 14217035 14252953 14525708 14569194 14625479 14647326 14656954 14796401 15029629 15238735 15314607 15411558 15416542 15420570 15444249 15446312 15502475 15502475 15550726 15776016 15933073 16455111 16891372 17436914 17474955 17665154 17784868 18124148 18128395 18467129 18864395 18882298 18944275 19009073 19021641 19055135 19059377 19117312 19171181 19196225 19280729 19728319 19735990 19843616 19907456 20423663 20496276 20708598 20716021 20781286 20824078 21014743 21329802 21487153 21500122 21502502 21518827 21519333 21566556 21592500 21683491 21694301 21725970 21733359 21958200

3.75 3.5 6.33333 6 5.5 5.5 4 5 7 11 3 5 7.33333 3.83333 4.25 4.5 6 7.5 4.5 4.75 6 7.5 5.5 6.25 4.5 10 6.5 4.75 3.6 5.5 6.5 6.66667 7 6.5 5.4 8 8 5.66667 5.5 6.5 4 5.5 3.83333 4 6.2 5 6.75 6.33333 5 5 7 5 7.75 6 8.33333 6.5 8 4.66667 5.33333 3.25 3.75 3.5 5.5 8 3.75 5 8 8.5 4.75 7 6.5 3.83333 4.75 12.5 6 6.66667 7.66667 15.5 5.25 6.25 5.66667 7 6.8 5

. . . ENSSSCT00000007691 ENSSSCT00000007691 . . . . . . ENSSSCT00000030178 ENSSSCT00000030178 . ENSSSCT00000028117 ENSSSCT00000028117 . . . ENSSSCT00000007705 . . ENSSSCT00000027193 . . ENSSSCT00000007708 . . ENSSSCT00000026119 . . . . . . ENSSSCT00000026307 ENSSSCT00000007712 . . ENSSSCT00000007716 ENSSSCT00000007723 . . . . . . . . ENSSSCT00000027927 . . . . . . . . . . ENSSSCT00000007727 ENSSSCT00000007727 ENSSSCT00000007727 . . . ENSSSCT00000007729 ENSSSCT00000007729 . . . . . . . . . . . ENSSSCT00000030392 ENSSSCT00000030392 . . ENSSSCT00000007737

. . . ANK1 ANK1 . . . . . . . . . . . . . . . . . RASSF2 . . PRNP . . PROKR2 . . . . . . GPCPD1 GPCPD1 . . MCM8 FERMT1 . . . . . . . . HAO1 . . . . . . . . . . PLCB1 PLCB1 PLCB1 . . . PLCB4 PLCB4 . . . . . . . . . . . . . . . SLX4IP

intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intron intron intergenic intergenic intergenic promoter intergenic intergenic intron intergenic intergenic 3'utr intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intron

. . -0.228 2.39 0.053 -0.151 . -0.004 . 0.398 -0.066 -0.04 . . -0.1 . . . . -0.171 . . . -0.033 -0.069 0.675 . 0.185 -0.052 0.136 . . . 0.032 -0.306 0.163 0.163 . . 0.384 -0.077 0.222 . . 0.083 0.008 0.022 0.415 . 0.409 -0.08 0.185 -0.017 . . 0.339 0.148 1.365 -0.062 -0.107 0.022 0.077 . 0.269 -1.678 0.148 3.708 . -0.12 0.037 . -0.129 0.147 0.181 0.157 -0.15 0.042 . . 0.173 0.095 -0.028 -0.047 0.074

. . rs787159455 348299 rs7908 rs790923318 rs790093760 rs792592164 rs793755734 377877 rs7899 236450 rs7931 . . 223977 rs7877 761517 rs7878 rs790633316 783734 rs7873 271028 rs7867 rs788706539 rs787098090 rs793177169 018169 rs7878 . rs787735379 rs789716429 rs786531169 . rs792037222 553161 rs7900 rs787692585 . rs793837290 rs791227246 rs792984559 509303 rs7928 rs791882511 rs787536891 rs787536891 rs791103244 rs790963178 rs793726909 rs792786546 . . 363157 rs7909 rs700211501 rs790468422 432154 rs7896 546384 rs6929 165261 rs7886 rs700404212 rs793625297 rs793888166 rs788289848 rs787403886 rs790961227 rs792165263 rs786255526 rs791930312 671952 rs7882 970571 rs7931 559490 rs7890 rs786290398 rs786437327 rs789720474 rs789450849 . 513010 rs7010 . rs786610494 722427 rs7880 rs791698454 957934 rs7919 . rs792509019 918067 rs7898 898085 rs7918 605882 rs7904 472045 rs7876 rs793082830 890527 rs7898 683530 rs7868 146834 rs7915 523388 rs7905 026462 rs7915

2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 3 2 2 2 4 3 2 3 3 2 2 3 2 2 3 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 3 2 2 3 2 2 2 2 3 2 2 2 5 3 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2

AAC.GTT AC.GT AG.CT AT.AT AC.GT AAAT.ATTT AAT.ATT AAGG.CCTT AC.GT AAAC.GTTT AC.GT ACC.GGT AC.GT AAT.ATT AT.AT AAAC.GTTT AAT.ATT AG.CT AAAAC.GTTTT AAAT.ATTT AACT.AGTT AC.GT AG.CT AG.CT AT.AT AAAAC.GTTTT AT.AT AGC.GCT AAAT.ATTT AC.GT AAAAAC.GTTTTT AT.AT AG.CT AAG.CTT AAAC.GTTT AAAAC.GTTTT AC.GT AAAG.CTTT AAC.GTT AAAT.ATTT AAT.ATT AC.GT AG.CT AAT.ATT AC.GT AT.AT AC.GT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AAAAAC.GTTTTT AAAAAC.GTTTTT AAC.GTT AAC.GTT AT.AT AAAAC.GTTTT AT.AT AG.CT AT.AT AGG.CCT AGG.CCT AATG.CATT AAAG.CTTT AAAAAC.GTTTTT AAAAC.GTTTT ACT.AGT AAAG.CTTT AC.GT AC.GT AAAT.ATTT AAAAC.GTTTT AAG.CTT AAAAC.GTTTT AC.GT ACAT.ATGT AC.GT AG.CT AC.GT AC.GT AC.GT AC.GT AC.GT AC.GT AC.GT

17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17

22076880 22364515 22495915 22592726 22754677 23103541 23177053 23204029 23229580 23291492 23506987 23648671 23679140 23755438 23885199 24285509 24305341 24432542 24433395 24440481 24632251 24639124 24690554 24809670 25201249 25242255 25596123 25614867 25723656 25992365 26151466 26234030 26541955 26786043 26815779 26893814 26979556 27029140 27261267 27341953 27405128 27475194 27478411 27494475 27500262 28008962 28010601 28034470 28271561 28271561 28354947 28354947 28361349 28361349 28444180 28541590 28669231 28819083 28906857 29086814 29207583 29525980 29743647 29810482 30029186 30185161 30472464 30472879 30885413 30970372 31023536 31026511 31031568 31051526 31166172 31187489 31233914 31412684 31412684 31412684 31451902 31451902 31451902 31466732

22076896 22364529 22495924 22592739 22754696 23103556 23177077 23204040 23229594 23291508 23507005 23648690 23679152 23755454 23885218 24285535 24305357 24432558 24433433 24440493 24632265 24639136 24690564 24809682 25201261 25242278 25596135 25614882 25723679 25992401 26151483 26234040 26541966 26786067 26815798 26893834 26979576 27029160 27261287 27341976 27405152 27475203 27478426 27494488 27500276 28008971 28010611 28034491 28271575 28271575 28354965 28354965 28361362 28361362 28444201 28541610 28669244 28819097 28906868 29086846 29207603 29526016 29743658 29810507 30029204 30185178 30472486 30472889 30885441 30970389 31023555 31026525 31031596 31051540 31166203 31187499 31233924 31412701 31412701 31412701 31451916 31451916 31451916 31466743

5.66667 7.5 5 7 10 4 8.33333 3 7.5 4.25 9.5 6.66667 6.5 5.66667 10 6.75 5.66667 8.5 7.8 3.25 3.75 6.5 5.5 6.5 6.5 4.8 6.5 5.33333 6 18.5 3 5.5 6 8.33333 5 4.2 10.5 5.25 7 6 8.33333 5 8 4.66667 7.5 5 5.5 4.4 3.75 3.75 3.16667 3.16667 4.66667 4.66667 11 4.2 7 7.5 6 11 7 9.25 3 4.33333 3.8 6 5.75 5.5 14.5 4.5 4 5 5.8 7.5 8 5.5 5.5 9 9 9 7.5 7.5 7.5 6

ENSSSCT00000007738 . . . . . . . . . . . . . . . . ENSSSCT00000007743 ENSSSCT00000007743 ENSSSCT00000007743 . . . . ENSSSCT00000007749 ENSSSCT00000007749 . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000030802 ENSSSCT00000007751 ENSSSCT00000030802 ENSSSCT00000007751 ENSSSCT00000030802 ENSSSCT00000007751 . . . . . . ENSSSCT00000007755 . . . ENSSSCT00000022008 ENSSSCT00000007766 ENSSSCT00000007771 ENSSSCT00000007771 . . . . . . . . . ENSSSCT00000028523 ENSSSCT00000007772 ENSSSCT00000024048 ENSSSCT00000028523 ENSSSCT00000007772 ENSSSCT00000024048 ENSSSCT00000028523

JAG1 . . . . . . . . . . . . . . . . SPTLC3 SPTLC3 SPTLC3 . . . . SEL1L2 SEL1L2 . . . . . . . . . . . . . . . . . . . . . . KIF16B KIF16B KIF16B KIF16B KIF16B KIF16B . . . . . . PCSK2 . . . U6 . SCP2D1 SCP2D1 . . . . . . . . . . . . . . . .

intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic promoter intron promoter promoter intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intron

-0.1 0.097 0.067 0.082 . . -0.044 -0.059 0.197 0.174 0.229 0.192 0.038 . -0.127 -0.228 . -0.045 -0.337 0.128 0.099 0.096 0.035 0.186 0.037 0.266 . 0.125 0.223 0.024 . 0.044 0.081 -0.067 0.122 . 0.055 0.751 0.121 0.032 -0.007 0.303 -0.009 0.027 . -0.036 . . . . -0.063 -0.063 0.053 0.053 . 0.58 . 0.214 . 0.061 -0.198 0.092 -0.101 0.116 . . 0.062 0.642 -0.477 -0.412 -0.094 0.006 . -0.533 . -0.101 -0.022 0.058 0.058 0.058 -0.197 -0.197 -0.197 -0.193

rs789609887 . rs787880805 804262 rs7880 rs793400492 rs789940311 rs792646305 . rs790329930 rs788466079 728073 rs7921 rs793348122 . rs790879274 875132 rs7884 rs789245939 rs789420133 . 808090 rs7910 rs793565688 452503 rs7888 rs788808200 rs786692219 rs790932374 539279 rs7912 . 223497 rs7909 940918 rs7871 rs789465956 . 284385 rs7936 . rs789430745 855760 rs7920 rs789124219 308331 rs7876 rs793554991 . rs786838129 275642 rs7929 162785 rs7908 rs787343614 rs793832608 044342 rs7862 rs788747993 rs788368965 . rs787694790 rs791393125 rs791393125 rs791113750 rs791113750 rs788279451 rs788279451 rs791523716 862898 rs7881 rs793213335 rs792074641 rs789148591 rs788566202 . rs789121172 rs791238635 rs792486788 rs790183053 rs788055647 rs787897889 rs788267253 . . rs790887252 rs790979159 rs793677976 rs789325850 rs789825753 rs788302377 170604 rs7868 . . . rs790325298 rs790325298 rs790325298 .

2 2 2 2 3 5 2 2 3 2 2 3 3 2 2 2 2 4 4 2 2 2 3 2 2 2 2 2 2 2 2 2 3 3 2 2 2 2 2 3 2 2 3 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 3 2 2 2 2 2 2 4 4 4 2

AC.GT AC.GT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAAT.ATTTT AT.AT AG.CT AAAC.GTTT AAAC.GTTT AC.GT AAAC.GTTT AAC.GTT AC.GT AC.GT ACAG.CTGT AAAT.ATTT AT.AT ACT.AGT AC.GT AC.GT AC.GT AC.GT AT.AT AAAAC.GTTTT AAAT.ATTT AGG.CCT AC.GT AC.GT AAAC.GTTT AC.GT AAC.GTT AC.GT AAAAT.ATTTT AAAC.GTTT AC.GT AG.CT AAG.CTT AAG.CTT AAAT.ATTT AAAT.ATTT AAAAT.ATTTT AAAC.GTTT AC.GT AAAAAC.GTTTTT AT.AT AAAC.GTTT ATCC.GGAT AAAT.ATTT AAAC.GTTT AAAT.ATTT AAC.GTT AC.GT AAAC.GTTT AC.GT AAC.GTT AAAAC.GTTTT AAAAC.GTTTT AAAAC.GTTTT AAAAC.GTTTT AAAT.ATTT AC.GT AAAT.ATTT AAAT.ATTT AAAAC.GTTTT AG.CT AAC.GTT AAAC.GTTT AC.GT AATG.CATT AT.AT AAAC.GTTT AAAAC.GTTTT AAAT.ATTT AT.AT AT.AT AAAC.GTTT AAAC.GTTT AC.GT AC.GT ACAT.ATGT AAAC.GTTT AG.CT AAC.GTT

17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17

31466732 31466732 31550016 31765305 31765305 31774068 32110314 32736340 32775463 32886719 33029088 33067336 33123465 33259634 33425247 33496456 33639789 34213113 34908194 34914680 34942541 35215896 35215896 35623738 36089940 36111478 36273861 36870393 37020875 37054130 37127854 37183875 37268979 37425494 38093682 38794016 39094704 39200287 39623004 39822466 39992547 40320809 40715817 40952673 40969434 41114297 41616021 41656314 42037072 42038183 42045443 42165140 42274878 42437701 42453328 42468831 43070855 43070855 43070855 43171147 43239906 43302469 43746636 43748657 43757898 43800079 44064192 44395668 44540480 44877272 45167571 45415812 45418303 45489992 45557309 45557309 45720774 45735846 45878990 46301814 46921715 47126753 47283004 47542861

31466743 31466743 31550036 31765328 31765328 31774086 32110325 32736349 32775480 32886738 33029100 33067355 33123480 33259645 33425281 33496480 33639815 34213123 34908220 34914691 34942553 35215919 35215919 35623748 36089959 36111496 36273883 36870405 37020885 37054150 37127864 37183886 37268993 37425510 38093699 38794029 39094719 39200299 39623024 39822483 39992571 40320827 40715831 40952684 40969455 41114315 41616035 41656346 42037087 42038209 42045467 42165153 42274888 42437724 42453338 42468855 43070878 43070878 43070878 43171171 43239934 43302483 43746653 43748675 43757916 43800093 44064208 44395682 44540491 44877287 45167581 45415836 45418325 45490004 45557328 45557328 45720785 45735869 45879000 46301843 46921729 47126771 47283016 47542873

6 6 5.25 6 6 3.8 6 5 4.5 5 6.5 5 5.33333 6 17.5 6.25 6.75 5.5 9 6 6.5 12 12 5.5 4 4.75 7.66667 6.5 5.5 5.25 5.5 4 7.5 3.4 4.5 7 8 4.33333 7 4.5 6.25 3.8 3.75 6 3.66667 9.5 3.75 8.25 4 6.75 6.25 4.66667 5.5 6 5.5 8.33333 4.8 4.8 4.8 5 7.25 7.5 4.5 4.75 3.8 7.5 5.66667 3.75 6 4 5.5 6.25 4.6 3.25 10 10 3 6 5.5 15 3.75 4.75 6.5 4.33333

ENSSSCT00000007772 ENSSSCT00000024048 . ENSSSCT00000023356 ENSSSCT00000007775 ENSSSCT00000023356 . . . . ENSSSCT00000007780 ENSSSCT00000007781 ENSSSCT00000007781 . . . . . ENSSSCT00000007803 ENSSSCT00000007803 ENSSSCT00000007804 ENSSSCT00000007807 ENSSSCT00000026945 . . . . . ENSSSCT00000007839 ENSSSCT00000007839 . ENSSSCT00000007840 ENSSSCT00000007844 . . . ENSSSCT00000007877 . ENSSSCT00000007890 . . . ENSSSCT00000007928 ENSSSCT00000007930 ENSSSCT00000007930 . ENSSSCT00000007941 . ENSSSCT00000030451 ENSSSCT00000030451 ENSSSCT00000030451 ENSSSCT00000007955 . . . . ENSSSCT00000007965 ENSSSCT00000036055 ENSSSCT00000036444 ENSSSCT00000007967 ENSSSCT00000007967 ENSSSCT00000025489 . . . . ENSSSCT00000024698 ENSSSCT00000007997 . ENSSSCT00000008003 . ENSSSCT00000008012 ENSSSCT00000008012 ENSSSCT00000008014 ENSSSCT00000028674 ENSSSCT00000023002 . . ENSSSCT00000008023 ENSSSCT00000024027 . . ENSSSCT00000008042 .

. intron . intron . intergenic . intron . intron . intron . intergenic . intergenic . intergenic . intergenic . intron XRN2 intron XRN2 intron . intergenic . intergenic . intergenic . intergenic . intergenic . intron . intron . intron NINL intron NINL intron . intergenic . intergenic . intergenic . intergenic . intergenic PTPRA intron PTPRA intron . intergenic VPS16 intron EBF4 intron . intergenic . intergenic . intergenic ANGPT4 intron . intergenic NRSN2 promoter . intergenic . intergenic . intergenic TM9SF4 intron ASXL1 intron ASXL1 intron . intergenic . intron . intergenic CBFA2T2 intron CBFA2T2 intron CBFA2T2 intron . intron . intergenic . intergenic . intergenic . intergenic ITCH intron ITCH intron ITCH intron PIGU intron PIGU intron TP53INP2 intron . intergenic . intergenic . intergenic . intergenic . intron RBM39 intron . intergenic EPB41L1 intron . intergenic NDRG3 intron NDRG3 intron SOGA1 intron SAMHD1 3'utr . 3'utr . intergenic . intergenic GHRH intron CTNNBL1 intron . intergenic . intergenic PPP1R16B intron . intergenic

-0.193 -0.193 -0.039 0.108 0.108 . 0.126 1.084 -0.075 0.208 -0.238 . -0.192 -0.102 -0.169 . -0.214 -0.354 -0.277 -0.728 0.052 -0.061 -0.061 -0.077 . 0.423 0.147 0.212 2.235 0.276 0.116 . 0.166 -0.14 0.008 0.228 -0.015 . 0.085 . . . 0.056 . -0.181 0.1 0.221 -0.182 . . -0.091 2.857 0.077 . 0.041 . . . . . . 0.381 . . . . . . 0.467 0.054 . 0.203 0.109 0.026 0.157 0.157 . . . 0.899 . -0.466 . .

. . 522613 rs7912 rs786414763 rs786414763 rs790111198 270587 rs7877 rs788431717 rs788061374 rs788938331 . . rs695856537 rs789475638 rs791593152 rs788073640 rs787673050 rs791933003 890048 rs7892 . 534822 rs7875 . . rs789988502 rs792814749 rs790726812 . rs791067662 rs788479611 rs791046241 . rs789244729 rs793088418 rs790066501 319226 rs7895 rs792557192 . rs790624803 rs787598028 rs788627349 rs790674418 rs789424556 rs792989989 rs793263044 rs787561533 rs792357156 rs786407133 620702 rs7875 rs787981246 rs787802748 416702 rs7910 rs789769921 . rs788584551 . rs791629325 rs786224516 rs786224516 rs786224516 287018 rs7872 rs791763004 867589 rs7899 rs786585630 rs793353344 rs789277823 rs786912706 rs787353273 768622 rs7884 . 455201 rs7934 rs789949945 rs793774537 891922 rs7912 rs792517554 rs793198034 rs793198034 . rs788091313 . 531262 rs7867 . rs789385262 . rs787786366

2 2 2 2 2 2 2 3 2 2 3 4 2 2 2 2 2 2 2 2 2 4 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 3 2 4 3 2 2 2 2 2 5 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 3

AAAC.GTTT AAAC.GTTT AAAAAC.GTTTTT AT.AT AC.GT AAT.ATT AAAT.ATTT AAAAG.CTTTT AAT.ATT AC.GT AG.CT AAAC.GTTT AC.GT AAAC.GTTT AT.AT AAAAT.ATTTT AG.CT AC.GT AC.GT AAAACC.GGTTTT AG.CT AAAAC.GTTTT AG.CT AC.GT AG.CT AC.GT AC.GT AAAT.ATTT AC.GT AAAT.ATTT AAAC.GTTT AAAAC.GTTTT AAAAC.GTTTT AAAT.ATTT AAC.GTT AAAACC.GGTTTT AC.GT AT.AT AT.AT AG.CT AT.AT AAT.ATT AGC.GCT AG.CT AAGG.CCTT AC.GT AAAAAC.GTTTTT AAAC.GTTT AG.CT ACAG.CTGT AAAAG.CTTTT AATG.CATT AAAAC.GTTTT ATCC.GGAT AAAAAC.GTTTTT AAAAAC.GTTTTT AAAAAC.GTTTTT AAAAAC.GTTTTT AAAG.CTTT AC.GT AG.CT AAGG.CCTT AAGG.CCTT AAAG.CTTT ACAT.ATGT AT.AT AAG.CTT AC.GT AC.GT AG.CT AC.GT AC.GT AG.CT AAAAG.CTTTT AAG.CTT AT.AT AAAC.GTTT AC.GT AC.GT AC.GT AG.CT AC.GT AG.CT AC.GT

17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17

47553168 47747319 47829826 47886406 48558588 48619690 49069604 49121095 49129929 49599207 49626297 49885384 49944397 50129341 50530620 50587024 50609798 50622337 50763597 50879587 50892171 51348342 51359476 51885392 51990711 52000555 52000555 52568106 52748834 52787253 52832761 53279348 53279348 53519967 53566448 53591632 53615322 53633622 53633622 53848938 54295713 54374402 54917245 55023886 56820557 56869715 57054054 57249955 57390910 57429498 57620499 57655940 57890490 58310792 58815301 58815301 58815301 58815301 58993068 59057547 59082876 59235002 59235002 59677048 59717708 59853449 60052651 60066059 60183400 60602324 60720865 61067019 61196778 61221976 61333452 61339142 61376323 61552371 61738637 61861510 62729115 62842535 62932099 62995953

47553192 47747349 47829848 47886419 48558598 48619707 49069627 49121120 49129944 49599219 49626327 49885407 49944410 50129355 50530631 50587041 50609808 50622350 50763615 50879618 50892181 51348358 51359491 51885402 51990723 52000569 52000569 52568121 52748844 52787289 52832781 53279365 53279365 53519982 53566463 53591651 53615338 53633636 53633636 53848947 54295732 54374420 54917256 55023898 56820575 56869726 57054079 57249982 57390921 57429516 57620513 57655971 57890505 58310810 58815326 58815326 58815326 58815326 58993081 59057558 59082891 59235020 59235020 59677064 59717721 59853461 60052673 60066069 60183411 60602350 60720875 61067031 61196792 61221990 61333464 61339160 61376337 61552392 61738646 61861519 62729128 62842548 62932126 62995965

6.25 7.75 3.83333 7 5.5 6 6 5.2 5.33333 6.5 15.5 6 7 3.75 6 3.6 5.5 7 9.5 5.33333 5.5 3.4 8 5.5 6.5 7.5 7.5 4 5.5 9.25 5.25 3.6 3.6 4 5.33333 3.33333 8.5 7.5 7.5 5 10 6.33333 4 6.5 4.75 6 4.33333 7 6 4.75 3 8 3.2 4.75 4.33333 4.33333 4.33333 4.33333 3.5 6 8 4.75 4.75 4.25 3.5 6.5 7.66667 5.5 6 13.5 5.5 6.5 7.5 3 4.33333 9.5 3.75 11 5 5 7 7 14 6.5

. . . . . . . . . . ENSSSCT00000027570 . . . ENSSSCT00000029823 ENSSSCT00000029823 ENSSSCT00000029823 ENSSSCT00000029823 . . . . . ENSSSCT00000008064 ENSSSCT00000008064 ENSSSCT00000008064 ENSSSCT00000030459 . . . ENSSSCT00000008080 ENSSSCT00000008095 ENSSSCT00000008102 . . . . ENSSSCT00000008124 ENSSSCT00000008123 ENSSSCT00000008141 . ENSSSCT00000008150 ENSSSCT00000008157 ENSSSCT00000008157 . . ENSSSCT00000008164 ENSSSCT00000026255 ENSSSCT00000008166 ENSSSCT00000008166 . . ENSSSCT00000029578 . ENSSSCT00000008179 ENSSSCT00000033789 ENSSSCT00000034996 ENSSSCT00000034352 . . . ENSSSCT00000034393 ENSSSCT00000008184 . . . . . . . . ENSSSCT00000034759 ENSSSCT00000034759 ENSSSCT00000034759 . . . . ENSSSCT00000008194 . . . . .

. . . . . . . . . . . . . . PTPRT PTPRT PTPRT PTPRT . . . . . . . . . . . . PABPC1L . . . . . . WFDC3 WFDC3 SLC12A5 . . EYA2 EYA2 . . ARFGEF2 . KCNB1 KCNB1 . . UBE2V1 . DPM1 DPM1 DPM1 DPM1 . . . NFATC2 NFATC2 . . . . . . . . TSHZ2 TSHZ2 TSHZ2 . . . . BCAS1 . . . . .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intron 3'utr intron intergenic intergenic intergenic intergenic intron intron intron intergenic promoter intron intron intergenic intergenic intron intron intron intron intergenic intergenic intron intergenic intron intron intron promoter intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic

-0.067 . -0.061 0.178 -0.137 0.109 . 0.301 0.236 0.222 0.311 0.032 0.129 . -0.236 -0.107 0.411 -0.23 0.037 -0.083 -0.073 0.34 -0.247 -0.131 . . . . . . -0.014 . . 0.052 . . 0.01 0.001 0.001 0.138 0.024 . 0.089 -0.266 -0.18 . -0.07 -0.158 -0.182 -0.534 0.221 0.259 -0.177 -0.334 0.044 0.044 0.044 0.044 -0.008 0.294 0.106 -0.151 -0.151 . . 0.048 -0.043 0.096 -0.316 0.025 0.339 -0.16 0.184 -0.409 . 0.101 0.107 0.297 -0.337 -0.092 0.547 -0.041 . -0.296

rs787770571 661536 rs7896 rs793244534 rs792227898 . rs791840147 638568 rs7931 rs789510259 rs786825039 rs786536495 rs788981323 996537 rs7906 073244 rs7887 rs789695156 rs790101313 rs788705093 rs788837009 rs793106284 971062 rs7935 rs790629617 rs792198746 rs787895442 rs792716598 rs789274346 . rs791707390 rs791707390 rs792815840 rs788659010 . 216722 rs7901 rs792123636 rs792123636 753629 rs7927 rs789781051 rs792812495 . 971053 rs7908 971053 rs7908 rs793605231 . rs786830462 967974 rs7865 592380 rs7903 rs792826776 rs704343609 rs793276396 rs789630884 rs790360582 rs790063358 rs790011982 273254 rs7936 rs790296074 . 751851 rs7882 751851 rs7882 751851 rs7882 751851 rs7882 600567 rs7880 . rs788656405 785162 rs7916 785162 rs7916 rs786668978 . rs698645216 . rs793759247 rs789206155 277253 rs7862 rs788386399 924910 rs7908 . rs788945266 774386 rs7900 . 385620 rs7881 rs786929085 542762 rs7910 rs789471760 rs789714250 823606 rs7892 rs786365080 .

2 2 2 3 3 2 2 2 2 2 2 2 2 2 4 2 2 2 2 3 2 2 3 2 2 2 2 2 2 2 2 2 2 2 4 2 3 2 2 2 2 2 2 3 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 3 2 4 2 4

AATG.CATT AT.AT AAT.ATT AAAAAC.GTTTTT AAAAG.CTTTT AC.GT AT.AT AAAT.ATTT AAAG.CTTT AAAG.CTTT AC.GT AC.GT AAC.GTT AAC.GTT AAC.GTT AAAC.GTTT AC.GT AAAATT.AATTTT AATG.CATT AGG.CCT AC.GT ATCC.GGAT AC.GT AT.AT AC.GT AAAAC.GTTTT AAGG.CCTT AC.GT AAAAT.ATTTT AAAAT.ATTTT AAAAT.ATTTT AG.CT AGGC.GCCT AAAT.ATTT AC.GT AC.GT AC.GT AC.GT AC.GT AG.CT AAAC.GTTT AAAAT.ATTTT AC.GT AAAC.GTTT AAGC.GCTT AAAC.GTTT AT.AT AAAC.GTTT AAAAC.GTTTT AAC.GTT AAC.GTT AAC.GTT AC.GT AC.GT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT ACCT.AGGT AAAG.CTTT AAAC.GTTT AAAC.GTTT AC.GT AAAAC.GTTTT AAT.ATT AAC.GTT AC.GT AAAAT.ATTTT AC.GT AAAT.ATTT AC.GT AT.AT AC.GT AATC.GATT AAAC.GTTT AAAC.GTTT AGC.GCT AT.AT AAAC.GTTT AAAAG.CTTTT AAGAG.CTCTT AG.CT ACGC.GCGT AAC.GTT

17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18

63118150 63210011 63235254 63458339 63562812 63631321 63640926 63900424 64070393 64070393 64123581 64123581 64183024 64183024 64183024 64375556 64504561 64644981 64657987 64712026 65387499 65477889 65535731 65555021 65591794 65717256 66840156 66913966 67153397 67153397 67446205 67447916 67539637 67720405 68087358 68370597 68391072 68456453 68684460 69068456 56411 2810648 3811552 3862549 4339929 4416305 4531456 4689169 4888123 4965017 4965017 5309670 5444278 5618849 5663877 5753671 5811201 6037277 6292701 7165057 7236549 7247813 7396246 7409125 7556080 7619682 7633946 7828858 7963707 8058835 8249421 8302072 8323815 8336022 8382738 8382738 8446572 8493780 8686988 9034596 9192972 9330637 9369605 9408946

63118172 63210020 63235268 63458358 63562827 63631333 63640939 63900438 64070407 64070407 64123591 64123591 64183037 64183037 64183037 64375573 64504588 64644999 64658004 64712040 65387511 65477914 65535742 65555030 65591804 65717282 66840175 66913975 67153415 67153415 67446227 67447928 67539659 67720423 68087367 68370608 68391091 68456478 68684484 69068474 56427 2810663 3811569 3862566 4339943 4416317 4531474 4689186 4888147 4965028 4965028 5309694 5444290 5618861 5663897 5753689 5811216 6037304 6292714 7165075 7236570 7247835 7396258 7409139 7556093 7619698 7633959 7828873 7963720 8058850 8249441 8302081 8323826 8336043 8382751 8382751 8446590 8493798 8687003 9034616 9192990 9330651 9369620 9408968

5.75 5 5 3.33333 3.2 6.5 7 3.75 3.75 3.75 5.5 5.5 4.66667 4.66667 4.66667 4.5 14 3.16667 4.5 5 6.5 6.5 6 5 5.5 5.4 5 5 3.8 3.8 4.6 6.5 5.75 4.75 5 6 10 13 12.5 9.5 4.25 3.2 9 4.5 3.75 3.25 9.5 4.5 5 4 4 8.33333 6.5 6.5 4.2 4.75 4 5.6 3.5 4.75 5.5 5.75 6.5 3 4.66667 5.66667 7 3.2 7 4 10.5 5 6 5.5 3.5 3.5 6.33333 9.5 4 4.2 3.8 7.5 4 7.66667

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000036639 AURKA intron ENSSSCT00000008202 AURKA intron ENSSSCT00000036338 CASS4 intron ENSSSCT00000008204 CASS4 intron ENSSSCT00000033915 RTFDC1 intron ENSSSCT00000008206 RTFDC1 intron ENSSSCT00000036126 RTFDC1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000008225 17H20ORF8 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000036671 PHACTR3 intron ENSSSCT00000035421 PHACTR3 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000008269 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000017888 XRCC2 intron ENSSSCT00000017887 ACTR3B intron . . intergenic ENSSSCT00000022851 . promoter ENSSSCT00000017891 GALNT11 intron ENSSSCT00000017892 GALNTL5 intron . . intergenic ENSSSCT00000025093 . intron ENSSSCT00000017895 RHEB intron ENSSSCT00000017897 ssc-mir-671 promoter ENSSSCT00000017925 CLCN1 intron ENSSSCT00000017929 GSTK1 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000017936 KEL intron . . intergenic . . intergenic . . intergenic ENSSSCT00000017947 . intron ENSSSCT00000017951 . intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000027750 CLEC5A intron ENSSSCT00000031347 CLEC5A intron . . intergenic . . intergenic ENSSSCT00000017956 AGK intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000014715 MRPS33 promoter

-0.17 -0.025 -0.021 -0.109 0.007 0.663 -0.028 0.49 . . -0.013 -0.013 -0.097 -0.097 -0.097 0.042 -0.443 -0.258 -0.297 -0.49 -0.367 -0.446 -0.185 . -0.173 0.252 -0.43 -0.464 -0.376 -0.376 -0.037 0.404 -0.039 -0.255 0.772 -0.195 -0.511 -0.279 . . 0.108 . -0.257 -0.265 -0.477 -0.16 -0.281 -0.023 0.14 -0.139 -0.139 . -0.046 . -0.107 . -0.227 . -0.113 2.402 0.02 . . . -0.365 -0.102 0.062 . -0.291 0.145 . -0.028 -0.106 0.23 -0.152 -0.152 . . -0.07 -0.2 -0.034 0.162 0.184 0.299

rs786459929 rs789618714 . rs787152782 952926 rs7864 673006 rs7910 . 905874 rs7913 rs793883159 rs793883159 rs793612080 rs793612080 . . . 946317 rs7935 799626 rs7897 . rs791688942 rs790085415 rs787555801 rs788306071 221018 rs7905 . . 431444 rs7867 rs786747283 . 473426 rs7898 473426 rs7898 rs698287139 rs792013594 . rs787840688 rs791133304 rs788824286 . rs786418583 rs793217486 rs787750384 390708 rs7909 rs792338680 rs791615176 rs789346633 884215 rs7890 734693 rs7888 . rs791183761 rs788251996 rs787696050 rs787696050 655472 rs7934 rs787049062 rs792081555 711972 rs7865 rs792749474 rs788391813 664163 rs7906 . rs789811323 rs699773451 826275 rs7923 874058 rs7934 rs792133428 . rs791010246 . rs786849328 . rs790760811 rs788874354 rs786649124 . rs788822990 rs788897591 rs788897591 119213 rs7868 rs787307952 131785 rs7880 rs790585470 287691 rs7910 rs789450604 rs693217313 rs792001318

2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 3 2 3 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 3 3 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2

AC.GT AT.AT AAAAT.ATTTT AC.GT AAAC.GTTT AAAC.GTTT AC.GT AC.GT AT.AT AC.GT AAAT.ATTT AAC.GTT AAAAAC.GTTTTT AC.GT AGG.CCT AAAT.ATTT AT.AT AAC.GTT AAAC.GTTT AC.GT AAC.GTT AT.AT AG.CT AAT.ATT ATC.GAT AC.GT AAAAC.GTTTT AC.GT AT.AT AAC.GTT AG.CT AAAAT.ATTTT AG.CT AT.AT AT.AT AAC.GTT AT.AT ACAG.CTGT AC.GT AC.GT AC.GT AC.GT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AT.AT AT.AT AT.AT AAAC.GTTT AAAC.GTTT AAAC.GTTT AC.GT AC.GT AC.GT AC.GT ACTC.GAGT AAC.GTT AT.AT AAAAAC.GTTTTT AAAT.ATTT AAAAC.GTTTT AAAG.CTTT AGAT.ATCT AATG.CATT AG.CT AT.AT AAC.GTT AG.CT AAAC.GTTT AC.GT AAGG.CCTT AAAG.CTTT AATG.CATT AAAACC.GGTTTT AAAC.GTTT AT.AT AC.GT AAAT.ATTT AAAC.GTTT AGGG.CCCT ACAT.ATGT AAAT.ATTT AC.GT

18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18

9515536 9545131 9651380 9656100 9672151 9672151 9808556 9873945 10011874 10266855 10764279 10783564 10833424 11040499 11356634 11473681 11681229 11695404 11731638 12133802 12178525 12183751 12209006 12316745 12408708 12430275 12585728 13007554 13088554 13191777 13214442 13585131 13713288 13786441 13818325 14269860 14306414 14586922 14801094 14974833 14995444 15029288 15041100 15087385 15087385 15087385 15111619 15111619 15111619 15138225 15138225 15138225 15140245 15140245 15140245 15277391 15342632 15495330 15624252 15826298 15924495 15939248 15944905 15979491 16100932 16176162 16200780 16268540 16529059 16669411 16790552 16948823 16987279 17025897 17034827 17054362 17067127 17180585 17227523 17237897 17256814 17578640 17854641 18007810

9515548 9545140 9651399 9656112 9672174 9672174 9808567 9873961 10011884 10266868 10764302 10783584 10833450 11040517 11356656 11473694 11681244 11695426 11731656 12133814 12178539 12183764 12209024 12316767 12408720 12430285 12585759 13007566 13088573 13191792 13214451 13585154 13713297 13786451 13818335 14269874 14306423 14586939 14801106 14974845 14995456 15029300 15041118 15087403 15087403 15087403 15111632 15111632 15111632 15138243 15138243 15138243 15140255 15140255 15140255 15277403 15342647 15495357 15624261 15826317 15924519 15939277 15944916 15979529 16100953 16176174 16200789 16268552 16529077 16669432 16790568 16948836 16987292 17025915 17034844 17054376 17067137 17180617 17227549 17237916 17256829 17578656 17854658 18007822

6.5 5 4 6.5 6 6 6 8.5 5.5 7 6 7 4.5 9.5 7.66667 3.5 8 7.66667 4.75 6.5 5 7 9.5 7.66667 4.33333 5.5 6.4 6.5 10 5.33333 5 4.8 5 5.5 5.5 5 5 4.5 6.5 6.5 6.5 6.5 4.75 4.75 4.75 4.75 7 7 7 4.75 4.75 4.75 5.5 5.5 5.5 6.5 4 9.33333 5 3.33333 6.25 6 3 9.75 5.5 6.5 5 4.33333 9.5 5.5 8.5 3.5 3.5 4.75 3 3.75 5.5 16.5 6.75 5 4 4.25 4.5 6.5

. ENSSSCT00000017958 ENSSSCT00000017959 ENSSSCT00000017959 ENSSSCT00000017960 ENSSSCT00000028640 ENSSSCT00000017961 . ENSSSCT00000031418 ENSSSCT00000017968 ENSSSCT00000017974 ENSSSCT00000017974 . ENSSSCT00000017979 . ENSSSCT00000017985 . . . ENSSSCT00000017987 . . ENSSSCT00000017988 ENSSSCT00000017988 . . . . . . . . . . . . ENSSSCT00000026748 . . . . ENSSSCT00000017997 ENSSSCT00000017997 ENSSSCT00000027194 ENSSSCT00000018005 ENSSSCT00000031119 ENSSSCT00000027194 ENSSSCT00000018005 ENSSSCT00000031119 ENSSSCT00000027194 ENSSSCT00000018005 ENSSSCT00000031119 ENSSSCT00000027194 ENSSSCT00000018005 ENSSSCT00000031119 . . . . . ENSSSCT00000018012 ENSSSCT00000018012 ENSSSCT00000018012 ENSSSCT00000018012 ENSSSCT00000018013 ENSSSCT00000018013 ENSSSCT00000018013 ENSSSCT00000018013 . . . . . . . . . ENSSSCT00000018015 ENSSSCT00000018015 ENSSSCT00000018015 ENSSSCT00000018015 . . .

. BRAF NDUFB2 NDUFB2 ADCK2 ADCK2 DENND2A . . TBXAS1 . . . ZAP . SVOPL . . . . . . CREB3L2 CREB3L2 . . . . . . . . . . . . FAM180A . . . . AGBL3 AGBL3 CALD1 CALD1 CALD1 CALD1 CALD1 CALD1 CALD1 CALD1 CALD1 CALD1 CALD1 CALD1 . . . . . LRGUK LRGUK LRGUK LRGUK EXOC4 EXOC4 EXOC4 EXOC4 . . . . . . . . . CHCHD3 CHCHD3 CHCHD3 CHCHD3 . . .

intergenic intron intron promoter intron intron intron intergenic intron intron intron intron intergenic intron intergenic intron intergenic intergenic intergenic intron intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic promoter intergenic intergenic intergenic intergenic intron intron intron intron intron intron intron intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic

. 0.098 . . 0.058 0.058 . -0.121 . -0.018 0.119 . . -0.324 . -0.141 0.14 . . 0.074 . . 0.123 0.047 . 0.023 -0.392 . -0.102 -0.096 0.007 . -0.002 0.073 0.023 -0.367 -0.088 0.124 0.021 . . 2.151 . 1.326 1.326 1.326 0.153 0.153 0.153 0.041 0.041 0.041 . . . 0.16 -0.021 0.102 . . . 0.115 -0.063 -0.217 0.218 0.035 0.009 0.315 0.009 . . 0.051 . -0.118 0.12 0.267 -0.076 0.197 0.461 0.03 -0.156 0.096 . 0.585

457660 rs7899 rs789967096 497272 rs7886 . rs788652574 rs788652574 rs791493396 rs792750843 rs787946397 945489 rs7874 rs789533051 rs786992638 rs789123615 . rs789225819 . rs791701801 rs786349627 rs790886982 . 729634 rs7862 rs793593030 721569 rs7129 517536 rs7893 rs790356495 . rs789710996 119184 rs7877 rs695885752 rs793021436 . rs789574354 . 286195 rs7936 520595 rs7887 rs791469655 rs792507346 . rs789085790 rs792223271 rs791594755 rs789741943 316292 rs7867 090023 rs7866 090023 rs7866 090023 rs7866 263271 rs7871 263271 rs7871 263271 rs7871 064583 rs7883 064583 rs7883 064583 rs7883 . . . 916582 rs7886 . 684425 rs7914 . rs789383834 rs792788046 . rs787967301 rs787517879 rs791781695 rs791044847 rs789019683 614616 rs7914 448311 rs7871 rs793654091 428508 rs7913 . rs786393401 rs707096974 rs788290070 rs792843385 577427 rs7936 rs792959729 . rs790119189 942932 rs7894 rs787700919 rs788733363 rs787382619

2 2 3 2 2 2 2 5 3 3 2 4 2 2 2 2 2 3 3 2 2 2 3 2 2 4 2 4 2 2 3 2 4 2 2 2 2 2 2 2 5 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 3 4 2 3 2 2 2 2 2 2 3 2 2 2 2 3 2

AAAT.ATTT AAAG.CTTT AAC.GTT AC.GT AAAG.CTTT AT.AT AGAT.ATCT AAAC.GTTT AAC.GTT AAAAC.GTTTT AAAT.ATTT ACAT.ATGT AAAC.GTTT AT.AT AT.AT AAAAC.GTTTT AT.AT AAAAT.ATTTT AAAAAG.CTTTTT AAAG.CTTT AAAC.GTTT AATC.GATT AAG.CTT AAAAC.GTTTT AAAT.ATTT AAAC.GTTT AAAAT.ATTTT AT.AT AC.GT AAGG.CCTT AAAT.ATTT AT.AT AAAT.ATTT AAT.ATT AAG.CTT AAAAT.ATTTT AATC.GATT AAAC.GTTT AC.GT AAAAC.GTTTT AAAC.GTTT AAT.ATT AAAC.GTTT AAC.GTT AG.CT AT.AT AT.AT AAAC.GTTT AAAC.GTTT AGGG.CCCT AAAC.GTTT ACAT.ATGT AT.AT AATT.AATT AAAG.CTTT AC.GT AAAAAC.GTTTTT AAAC.GTTT AAAAC.GTTTT AT.AT AC.GT AG.CT AAAT.ATTT AATG.CATT AAAC.GTTT AC.GT AAT.ATT ACAG.CTGT AG.CT AC.GT AAAAAC.GTTTTT AG.CT AGG.CCT AAAAAC.GTTTTT AAGG.CCTT AAT.ATT AAC.GTT AAAT.ATTT AG.CT AC.GT AAC.GTT AGATAT.ATATCT AGG.CCT AAAC.GTTT

18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18

18275612 18347520 18484913 18546803 18769771 19103849 19206217 19256579 19376573 19537135 19606730 19664674 19975020 20345161 20401378 20457992 20724401 20954632 21010316 21398271 21505735 21836773 21842932 21874892 21891012 22040422 22058846 22113058 22347499 22522789 22592320 22593307 22749350 22803112 22887199 22917324 22985712 23072009 23149358 23237316 23346591 23526755 23601091 23724311 23749024 24071976 24119864 24539082 24579230 24755641 24913534 25421890 25453027 25526529 25549423 25567918 25727215 25760802 25777492 25933392 26462676 26484090 26509898 26802471 26976925 27014466 27090416 27182800 27261616 27460393 27518669 27609201 27904824 27933965 28016250 28128662 28189778 28601136 28995095 29227414 29256013 29478118 29489216 29613398

18275625 18347538 18484929 18546825 18769785 19103858 19206261 19256597 19376592 19537151 19606750 19664696 19975039 20345172 20401391 20458027 20724412 20954647 21010336 21398284 21505762 21836794 21842947 21874906 21891036 22040441 22058863 22113071 22347520 22522810 22592336 22593326 22749369 22803134 22887211 22917343 22985734 23072032 23149368 23237331 23346610 23526777 23601119 23724324 23749034 24071992 24119883 24539107 24579248 24755663 24913548 25421903 25453062 25526548 25549449 25567931 25727232 25760836 25777512 25933401 26462685 26484099 26509914 26802487 26976947 27014481 27090435 27182819 27261628 27460425 27518693 27609210 27904835 27933988 28016268 28128681 28189805 28601166 28995104 29227425 29256033 29478146 29489232 29613416

3.5 4.75 5.66667 11.5 3.75 5 11.25 4.75 6.66667 3.4 5.25 5.75 5 6 7 7.2 6 3.2 3.5 3.5 7 5.5 5.33333 3 6.25 5 3.6 7 11 5.5 4.25 10 5 7.66667 4.33333 4 5.75 6 5.5 3.2 5 7.66667 7.25 4.66667 5.5 8.5 10 6.5 4.75 5.75 3.75 3.5 18 5 6.75 7 3 8.75 4.2 5 5 5 4.25 4.25 5.75 8 6.66667 5 6.5 16.5 4.16667 5 4 4 4.75 6.66667 9.33333 7.75 5 6 7 4.83333 5.66667 4.75

. . . ENSSSCT00000018018 . . . ENSSSCT00000018023 . . . ENSSSCT00000018033 . ENSSSCT00000018038 ENSSSCT00000018038 ENSSSCT00000018038 ENSSSCT00000018042 ENSSSCT00000018054 . ENSSSCT00000018062 ENSSSCT00000018062 . . . . . . . . . . . ENSSSCT00000026245 ENSSSCT00000026245 ENSSSCT00000026245 ENSSSCT00000026245 ENSSSCT00000026245 ENSSSCT00000026245 . . . . . . . . . . . . . . . ENSSSCT00000018081 ENSSSCT00000018081 . . ENSSSCT00000018083 ENSSSCT00000018083 . ENSSSCT00000018085 . . . . . . ENSSSCT00000018090 ENSSSCT00000018092 ENSSSCT00000018092 ENSSSCT00000018092 . . . . . . . . . . . . .

. . . PODXL . . . COPG2 . . . . . AHCYL2 AHCYL2 AHCYL2 TNPO3 FAM71F1 . SND1 SND1 . . . . . . . . . . . GRM8 GRM8 GRM8 GRM8 GRM8 GRM8 . . . . . . . . . . . . . . . IQUB IQUB . . SLC13A1 SLC13A1 . CADPS2 . . . . . . FAM3C CPED1 CPED1 CPED1 . . . . . . . . . . . . .

intergenic intergenic intergenic intron intergenic intergenic intergenic intron intergenic intergenic intergenic intron intergenic intron intron intron intron intron intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intron intron intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intron 3'utr intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

. . -0.337 0.183 0.464 . 0.095 . . 0.038 0.289 -0.005 0.9 0.504 0.294 0.253 1.418 -0.013 . 0.043 0.3 0.094 0.051 0.262 0.052 -0.24 0.154 0.294 0.053 0.173 -0.144 -0.21 0.036 0.246 . . 0.185 0.142 -0.016 0.565 . -0.137 -0.021 . . 0.255 -0.06 0.134 0.239 0.467 0.074 0.168 0.144 0.045 . . 0.07 0.054 -0.099 . 0.189 0.149 -0.245 0.049 0.303 0.202 . -0.014 0.447 -0.022 0.029 . -0.165 0.632 0.081 0.186 0.123 . . 0.016 . -0.081 0.003 .

rs786657237 612772 rs7864 rs793015349 rs790815607 985954 rs7929 rs791559372 rs791223942 rs711299152 695185 rs7910 rs790320941 rs788783939 rs793366343 rs792972156 rs786729614 rs788822027 rs791774346 531878 rs7881 597226 rs7892 rs791968280 rs792404525 rs790339144 . rs789598817 . . rs788575647 rs786256687 256502 rs7929 342303 rs7886 rs790621780 rs789906304 rs787362769 rs786491091 rs793249297 rs792067490 rs790663652 rs788874775 498947 rs7873 485946 rs7875 469267 rs7937 rs788445775 rs787857474 rs787739093 869266 rs7935 rs792108976 rs786340368 . rs791486857 rs788360059 rs791035565 rs788344979 . rs790257064 rs786870143 448296 rs7864 rs690070626 591984 rs7871 rs787687059 281221 rs7897 . 460321 rs7902 . rs789325119 856623 rs7899 rs787177690 rs789337720 . rs788697225 rs787141374 . rs787130159 . rs790873383 672307 rs7866 rs789123284 646547 rs7882 . rs793331203 . . 781304 rs7876 rs790656194 rs787925493 rs790396035

2 2 3 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 3 2 2 3 2 3 2 4 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 3 2 2 2 2 2

AAAC.GTTT AAC.GTT AAGC.GCTT AC.GT AAAC.GTTT AAAC.GTTT AAAT.ATTT AT.AT AATG.CATT AATC.GATT ACAG.CTGT AG.CT AAC.GTT AAG.CTT AAAG.CTTT AAAAT.ATTTT AAAAT.ATTTT AAAT.ATTT AAAC.GTTT AG.CT AAG.CTT AT.AT AT.AT AC.GT AAAC.GTTT AAAC.GTTT AAG.CTT AAC.GTT AAAC.GTTT AC.GT AAACAG.CTGTTT AC.GT AAAC.GTTT AAAAT.ATTTT AT.AT AAAC.GTTT AC.GT AAAC.GTTT AAAT.ATTT AAAC.GTTT AGC.GCT AC.GT AAC.GTT AAC.GTT AC.GT AAAAC.GTTTT AC.GT AT.AT AG.CT AC.GT AAAC.GTTT AAAG.CTTT AAC.GTT AAG.CTT AC.GT AC.GT AAC.GTT AC.GT AC.GT AT.AT AAAG.CTTT AAAAC.GTTTT AG.CT AAAC.GTTT AT.AT AAAAT.ATTTT AAACC.GGTTT AAAC.GTTT AG.CT AAAC.GTTT AAC.GTT AC.GT AC.GT AC.GT AT.AT ACC.GGT AAAAC.GTTTT AC.GT AG.CT AC.GT AC.GT AC.GT AGG.CCT AGG.CCT

18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18

29872418 29886942 29925496 30015962 30111118 30323447 30630290 30667954 30684276 31024968 31161136 31464147 31812705 31932602 32030134 32233824 32233824 32448761 32802941 32859642 32867501 33289759 33600130 33876928 33946419 34276943 34308396 34391795 34526024 34530406 34634680 34919230 34920381 35003756 35062064 35182434 35432138 35646018 35780645 35804900 35896563 35922783 36246849 36423451 36587845 36605075 36620069 36808358 36898294 36930633 37139015 37230221 37279350 37301080 37306998 37501176 37504491 37521026 37543188 37708105 37822343 37894255 38083039 38157373 38285947 38313825 39287308 39288314 39551698 39557788 40254145 40292121 40432831 40521637 40633517 40736276 40741342 40973098 40979294 41120603 41120603 41120603 41159443 41159443

29872432 29886958 29925513 30015982 30111137 30323465 30630310 30667968 30684293 31024995 31161156 31464159 31812734 31932616 32030162 32233839 32233839 32448781 32802955 32859656 32867520 33289770 33600139 33876947 33946441 34276965 34308410 34391813 34526054 34530417 34634703 34919250 34920394 35003776 35062077 35182446 35432149 35646047 35780675 35804918 35896582 35922792 36246862 36423465 36587859 36605099 36620081 36808368 36898303 36930642 37139043 37230241 37279368 37301093 37307007 37501187 37504504 37521037 37543207 37708115 37822361 37894276 38083054 38157391 38285960 38313851 39287332 39288333 39551735 39557813 40254158 40292143 40432844 40521646 40633533 40736291 40741372 40973108 40979304 41120615 41120615 41120615 41159457 41159457

3.75 5.66667 4.5 10.5 5 4.75 5.25 7.5 4.5 7 5.25 6.5 10 5 7.25 3.2 3.2 5.25 3.75 7.5 6.66667 6 5 10 5.75 5.75 5 6.33333 7.75 6 4 10.5 3.5 4.2 7 3.25 6 7.5 7.75 4.75 6.66667 5 4.66667 5 7.5 5 6.5 5.5 5 5 7.25 5.25 6.33333 4.66667 5 6 4.66667 6 10 5.5 4.75 4.4 8 4.75 7 5.4 5 5 19 6.5 4.66667 11.5 7 5 8.5 5.33333 6.2 5.5 5.5 6.5 6.5 6.5 5 5

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000018099 CTTNBP2 intron ENSSSCT00000018103 . intron . . intergenic . . intergenic . . intergenic ENSSSCT00000018105 ST7 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000018115 TFEC intron ENSSSCT00000028328 TFEC intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000018116 MDFIC intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000018124 IFRD1 intron . . intergenic ENSSSCT00000029218 . intron ENSSSCT00000029218 . intron ENSSSCT00000029218 . intron ENSSSCT00000029218 . intron ENSSSCT00000018126 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000018133 GPR141 promoter . . intergenic . . intergenic . . intergenic ENSSSCT00000018134 ELMO1 intron ENSSSCT00000018134 ELMO1 intron ENSSSCT00000018134 ELMO1 intron ENSSSCT00000018134 ELMO1 intron ENSSSCT00000018134 ELMO1 intron ENSSSCT00000018135 AOAH intron ENSSSCT00000034056 AOAH intron ENSSSCT00000033857 AOAH intron ENSSSCT00000018135 AOAH intron ENSSSCT00000034056 AOAH intron

0.064 0.101 -0.028 0.128 0.02 -0.073 0.177 0.214 0.495 0.198 0.232 -0.044 . . 0.106 0.008 0.008 -0.008 . -0.215 -0.051 -0.134 0.282 0.933 . 0.123 -0.047 -0.2 . 0.013 . . -0.005 0.161 . . 0.991 . 0.228 . -0.071 2.145 0.198 -0.09 0.03 0.063 . 0.096 -0.147 . 0.006 0.024 -0.035 0.183 0.041 . 0.453 0.086 0.067 0.015 0.151 . -0.235 . -0.051 0.093 . . 0.193 0.042 . -0.143 0.406 0.229 -0.029 -0.132 0.074 -0.014 -0.005 0.16 0.16 0.16 -0.056 -0.056

rs790719667 rs786704097 rs788076387 275816 rs7865 941162 rs7897 018706 rs7906 rs792793783 . rs790712722 646336 rs7880 . rs790774994 758282 rs7910 787182 rs7915 rs787749626 rs790937285 rs790937285 rs788461917 rs790194149 . rs788322948 900069 rs7919 rs788370305 . rs791230733 rs789370903 . rs792070720 . . . rs788388944 rs791131532 333296 rs7867 rs792542328 rs792846234 rs786320065 rs792940498 . rs793217187 rs790360418 rs789335076 . . . rs792521377 rs789596267 034550 rs7917 . . rs792300511 rs792201652 . 183477 rs7899 . rs792383278 rs792437008 rs788743908 . rs790473291 364674 rs7875 206496 rs7898 rs791114981 rs788211767 718419 rs7863 746388 rs7881 rs793242782 292128 rs7923 977812 rs7895 043788 rs7864 rs790011778 rs790398189 538015 rs7869 670350 rs7900 rs786973053 rs786508784 rs791476967 rs792686180 . rs790618579 rs790618579 rs790618579 903901 rs7901 903901 rs7901

2 2 2 2 2 2 3 3 2 2 2 3 4 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 3 3 2 2 2 2 2 2 2 2 2 2 2 2 4 2 5 2 2 2 3 2 3 2 2 2 4 4 2 3 2 2 2 2 3 3 2 2 2 2 2 2 2 2 4 3 4 2 2 2 2 4 4 4 2 2

AGG.CCT AG.CT AG.CT AT.AT AAAC.GTTT AAAC.GTTT AG.CT AT.AT AG.CT ACATAT.ATATGT ACATAT.ATATGT ACATAT.ATATGT AC.GT AC.GT AAAG.CTTT AAAG.CTTT AG.CT AAAC.GTTT AAC.GTT AAC.GTT AC.GT ACAG.CTGT AAAC.GTTT AG.CT AC.GT AC.GT ACCT.AGGT AAAC.GTTT AC.GT AAAG.CTTT AAAAC.GTTTT AAAAC.GTTTT AC.GT AC.GT AC.GT AAAAC.GTTTT AC.GT AT.AT AAAC.GTTT AAAG.CTTT AG.CT AC.GT AAGG.CCTT AG.CT AAAC.GTTT AAAC.GTTT AG.CT AAAAG.CTTTT AAAAC.GTTTT AG.CT AAC.GTT AAAG.CTTT AATG.CATT AT.AT AATC.GATT AG.CT AAAAC.GTTTT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AC.GT AT.AT AAAG.CTTT AAT.ATT ACACCC.GGGTG AT.AT AG.CT AAGG.CCTT AAC.GTT AAAAAC.GTTTTT AC.GT AC.GT AC.GT AAAAC.GTTTT AC.GT AAT.ATT AG.CT AAAT.ATTT AG.CT AG.CT AC.GT AAAC.GTTT AAAG.CTTT AAAT.ATTT

18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18

41159443 41309361 41824018 42184785 42271215 42280600 42390871 42752478 43044777 43276654 43276654 43276654 43334015 43334015 43390885 43390885 43667395 44229762 44237336 44461584 44663759 44696824 44777341 45102270 45181860 45217985 45320825 45358644 45415777 45418941 45751974 45751974 45792254 46197853 46218315 46683869 46718588 47217851 47516901 47663217 47672723 47760927 47951708 48140879 48141119 48264793 48303959 48307049 48412067 48704531 48883898 48907320 49018039 49177399 49191392 49331976 49350303 49350303 49415676 50240295 50845451 50848764 51179199 51192432 51295986 51357788 51606940 51989080 52028181 52249930 52342399 52342399 52342399 52438918 52576240 52814773 52927246 53069861 53092269 53204158 53307882 53310676 53473330 53502872

41159457 41309373 41824027 42184795 42271230 42280618 42390889 42752490 43044788 43276678 43276678 43276678 43334030 43334030 43390899 43390899 43667405 44229773 44237351 44461607 44663776 44696840 44777357 45102282 45181869 45217995 45320843 45358670 45415789 45418958 45751988 45751988 45792264 46197878 46218325 46683887 46718598 47217861 47516927 47663231 47672738 47760936 47951726 48140893 48141137 48264812 48303971 48307067 48412091 48704542 48883914 48907336 49018061 49177409 49191406 49331985 49350323 49350323 49415694 50240308 50845461 50848782 51179211 51192448 51296009 51357805 51606956 51989101 52028197 52249949 52342411 52342411 52342411 52438933 52576250 52814788 52927260 53069878 53092279 53204167 53307892 53310694 53473350 53502889

5 6.5 5 5.5 4 4.75 9.5 6.5 6 4.16667 4.16667 4.16667 8 8 3.75 3.75 5.5 3 5.33333 8 9 4.25 4.25 6.5 5 5.5 4.75 6.75 6.5 4.5 3 3 5.5 13 5.5 3.8 5.5 5.5 6.75 3.75 8 5 4.75 7.5 4.75 5 6.5 3.8 5 6 5.66667 4.25 5.75 5.5 3.75 5 4.2 4.2 4.75 3.5 5.5 9.5 3.25 5.66667 4 9 8.5 5.5 5.66667 3.33333 6.5 6.5 6.5 3.2 5.5 5.33333 7.5 4.5 5.5 5 5.5 4.75 5.25 4.5

ENSSSCT00000033857 ENSSSCT00000018136 . . . . . . . ENSSSCT00000029081 ENSSSCT00000023205 ENSSSCT00000018144 ENSSSCT00000029081 ENSSSCT00000018144 ENSSSCT00000029081 ENSSSCT00000018144 . ENSSSCT00000031056 ENSSSCT00000031056 ENSSSCT00000029905 . . ENSSSCT00000029825 . . . ENSSSCT00000018147 ENSSSCT00000018147 ENSSSCT00000018147 ENSSSCT00000018147 ENSSSCT00000018150 ENSSSCT00000023430 . . . ENSSSCT00000018157 ENSSSCT00000018157 . . ENSSSCT00000018168 ENSSSCT00000018168 . . . . ENSSSCT00000018171 ENSSSCT00000018171 ENSSSCT00000018171 . . . . . . . ENSSSCT00000036364 ENSSSCT00000018173 ENSSSCT00000036364 . . ENSSSCT00000018190 ENSSSCT00000018190 . . . . . . . . ENSSSCT00000018196 ENSSSCT00000028478 ENSSSCT00000030453 ENSSSCT00000018197 ENSSSCT00000018198 . . . . . ENSSSCT00000018200 ENSSSCT00000018200 . .

AOAH ANLN . . . . . . . BMPER BMPER BMPER BMPER BMPER BMPER BMPER . . . FKBP9 . . AVL9 . . . PDE1C PDE1C PDE1C PDE1C CCDC129 CCDC129 . . . GARS GARS . . CHN2 CHN2 . . . . . . . . . . . . . . TAX1BP1 TAX1BP1 TAX1BP1 . . SNX10 SNX10 . . . . . . . . OSBPL3 OSBPL3 OSBPL3 DFNA5 MPP6 . . . . . STK31 STK31 . .

intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intron intergenic intron intron intron intergenic intergenic intron intergenic intergenic intergenic intron intron intron intron intron intron intergenic intergenic intergenic intron intron intergenic intergenic intron intron intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic

-0.056 . -0.15 -0.04 . 0.229 0.11 -0.197 -0.183 . . . -0.096 -0.096 -0.123 -0.123 0.036 . 0.885 . . 0.123 . 0.231 -0.001 . 0.216 . 0.04 0.212 -0.022 -0.022 0.279 0.018 -0.095 0.073 . . . -0.049 0.104 -0.185 0.029 -0.175 -0.215 0.234 0.423 0.632 0.427 -0.078 0.149 0.505 . 0.005 -0.29 1.121 . . 0.066 0.724 0.227 1.09 0.012 0.396 0.706 . -0.055 0.215 . -0.038 . . . . 0.39 0.047 0.097 . 0.334 0.187 0.242 . . .

903901 rs7901 441284 rs7901 . rs792142099 072634 rs7895 rs792411311 . rs790105413 rs790040353 473135 rs7924 473135 rs7924 473135 rs7924 . . rs792186691 rs792186691 rs786557169 rs786441937 rs790125169 rs789306961 779460 rs7904 rs786546632 rs793190701 . 052707 rs7902 . rs792269315 rs792754433 rs786921455 rs789816560 878414 rs7869 878414 rs7869 . 585611 rs7874 rs792809600 rs792312282 . rs790073913 rs791040824 . . rs787229993 rs789639921 rs708248009 288535 rs7892 rs791037364 . . rs791409420 809101 rs7867 026902 rs7934 240486 rs7886 . rs791422392 rs792604424 . rs791389669 rs791389669 489896 rs7915 rs788834182 rs788260148 . rs791682250 rs792335094 . rs791248633 rs791815901 728562 rs7936 rs713405976 107354 rs7919 843916 rs7886 843916 rs7886 843916 rs7886 rs786929688 rs792289562 rs789291568 rs787722910 058498 rs7881 rs787293934 . 692971 rs7871 rs711574465 . rs791410620

2 2 2 3 2 2 4 3 2 2 2 2 4 4 2 2 2 2 2 2 2 2 2 4 3 4 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 4 3 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2

AC.GT AAAC.GTTT AC.GT AAAAT.ATTTT AAAC.GTTT AACC.GGTT AGC.GCT AC.GT AC.GT AAC.GTT AAAG.CTTT AT.AT AAAAC.GTTTT AAAG.CTTT AAC.GTT AAAG.CTTT AT.AT AAAT.ATTT AAAC.GTTT AT.AT AAAC.GTTT AAAAT.ATTTT AC.GT AAT.ATT AAAT.ATTT AAAC.GTTT AG.CT AAAT.ATTT AAT.ATT AC.GT AAAC.GTTT AAAG.CTTT AC.GT AC.GT AAT.ATT AAAT.ATTT AAAC.GTTT AAGG.CCTT AC.GT AC.GT AAAC.GTTT AC.GT AC.GT AC.GT AAAG.CTTT AAAC.GTTT AAAC.GTTT AC.GT AAAG.CTTT AT.AT AAAAG.CTTTT AT.AT AGGG.CCCT AAAT.ATTT AC.GT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAC.GTT AC.GT AAAC.GTTT AAC.GTT AC.GT AAAC.GTTT AT.AT AC.GT AAG.CTT AAC.GTT AAAAAC.GTTTTT AGG.CCT AAC.GTT AGG.CCT AGG.CCT AG.CT AAC.GTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AT.AT AAC.GTT AAT.ATT AG.CT AAAAC.GTTTT

18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 18 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2

54171718 54177831 54559085 54613180 54749453 54868455 55063082 55080555 55097381 55270490 55300118 55324387 55330252 55655281 55862960 55883948 56121758 56139399 56338189 56344021 56662106 56746489 57144526 57219453 57238571 57650571 57920861 57931973 58075328 58082080 58100859 58102093 58168203 58352888 58764277 58770041 58775118 58988461 59075823 59676748 59684163 59983698 60176643 60225079 60228659 278001 767768 840398 1993925 2184000 2219186 2234711 2609038 2812237 2999742 3771094 3837290 3837290 3952495 5253017 5530131 6170322 6392603 6592145 6839535 7997666 8013935 8016903 8207683 8404150 8985691 9438228 9718112 9718112 9981197 11710722 11818832 11931366 12176429 12176612 12245337 12617796 12654047 12899137

54171736 54177849 54559099 54613194 54749475 54868476 55063094 55080566 55097410 55270515 55300141 55324396 55330270 55655304 55862975 55883965 56121768 56139414 56338207 56344030 56662126 56746509 57144535 57219471 57238585 57650593 57920875 57931995 58075344 58082093 58100875 58102110 58168213 58352906 58764296 58770058 58775132 58988499 59075858 59676757 59684176 59983720 60176662 60225093 60228678 278028 767787 840417 1993952 2184009 2219208 2234721 2609049 2812267 2999751 3771117 3837313 3837313 3952512 5253032 5530142 6170337 6392640 6592155 6839554 7997677 8013946 8016927 8207703 8404170 8985705 9438239 9718128 9718128 9981206 11710742 11818851 11931404 12176444 12176638 12245369 12617812 12654062 12899155

9.5 4.75 7.5 3 5.75 5.5 4.33333 6 15 8.66667 6 5 3.8 6 5.33333 4.5 5.5 4 4.75 5 5.25 4.2 5 6.33333 3.75 5.75 7.5 5.75 5.66667 7 4.25 4.5 5.5 9.5 6.66667 4.5 3.75 9.75 18 5 3.5 11.5 10 7.5 5 7 5 10 7 5 4.6 5.5 3 7.75 5 4.8 6 6 4.5 5.33333 6 4 12.6667 5.5 5 6 6 8.33333 7 3.5 5 4 5.66667 5.66667 5 7 5 9.75 4 13.5 11 5.66667 8 3.8

. . . . . ENSSSCT00000018209 . . . . . . . ENSSSCT00000018228 ENSSSCT00000018232 . . . ENSSSCT00000018242 ENSSSCT00000018242 . . . . . ENSSSCT00000018246 . . . . . . . . . . . . . ENSSSCT00000018255 ENSSSCT00000018255 . . . . . . . . . . . . . ENSSSCT00000014085 . ENSSSCT00000014115 ENSSSCT00000014116 . . . . ENSSSCT00000026889 ENSSSCT00000014237 . . ENSSSCT00000024497 ENSSSCT00000024497 . ENSSSCT00000025488 ENSSSCT00000015890 . ENSSSCT00000014314 ENSSSCT00000014305 . . ENSSSCT00000014365 . . . . ENSSSCT00000014390 . ENSSSCT00000014398

. intergenic . intergenic . intergenic . intergenic . intergenic IGFBP1 promoter . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic NPC1L1 intron YKT6 intron . intergenic . intergenic . intergenic HECW1 intron HECW1 intron . intergenic . intergenic . intergenic . intergenic . intergenic . intron . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic CDK13 intron CDK13 intron . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic PPP6R3 intron . intergenic TBC1D10C 5'utr PPP1CA promoter . intergenic . intergenic . intergenic . intergenic ATG2A promoter NRXN2 intron . intergenic . intergenic . intron . promoter . intergenic BSCL2 intron . intron . intergenic DDB1 promoter DAK promoter . intergenic . intergenic DTX4 intron . intergenic . intergenic . intergenic . intergenic OR6Q1 promoter . intergenic ZDHHC5 intron

. . -0.009 -0.214 . . . -0.47 . . -0.244 0.197 0.225 0.04 0.157 . 0.155 . 0.047 0.147 0.135 0.2 0.276 -0.101 -0.405 0.961 -0.051 -0.054 0.047 -0.01 0.344 0.02 -0.025 0.134 . . . . 0.748 . . 0.132 0.17 0.026 -0.165 . . . . -0.11 . -0.454 -0.487 -0.16 -0.211 . 0.211 0.211 0.178 . . . 0.036 0.061 . . -0.445 . -0.088 -0.056 3.292 . -0.206 -0.206 . . -0.023 -0.59 . 0.318 -0.086 -0.184 . 0.382

rs793722620 465139 rs7886 rs791995221 rs791360732 rs788538873 651300 rs7890 rs789731776 . rs788862386 760458 rs7912 rs792309624 rs789547807 425092 rs7896 rs791733617 . rs790607305 . rs789429860 167144 rs7868 . . rs787812786 rs787740260 rs792919394 rs791033246 rs792864559 rs787116408 rs788273724 rs786345258 rs789033654 rs792729950 rs792532763 rs791233820 . rs792582410 . 150404 rs7912 rs786808874 rs791622845 rs788510794 rs789784177 rs793197482 . 560359 rs7894 rs791535772 564810 rs7917 103490 rs7899 511180 rs7916 rs790023774 . rs787235985 rs786901894 rs787531496 . . rs790131631 rs790893342 rs790893342 rs788800834 rs791406695 . 822689 rs7895 641086 rs7893 rs789225295 327488 rs7887 rs791382855 rs791202983 rs786732840 rs789759580 rs789499543 . 940625 rs7879 rs788596908 rs788596908 rs793875049 118469 rs7928 rs787285194 722318 rs7921 rs791191782 794714 rs7899 576231 rs7897 rs789362561 rs791793108 626449 rs7938

6 3 4 3 2 2 2 2 2 3 2 3 2 2 2 2 3 2 2 2 2 2 3 2 2 2 4 2 3 3 2 2 2 3 2 2 2 2 2 2 2 2 3 4 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 3 2 2 4 2 2 6 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2

AT.AT AGCCC.GGGCT AAAT.ATTT ACAG.CTGT AT.AT AC.GT AAAT.ATTT AG.CT AT.AT AATT.AATT AC.GT AAT.ATT AAC.GTT AC.GT AAAAAG.CTTTTT AAAT.ATTT AT.AT AAG.CTT AC.GT AG.CT AAAAT.ATTTT AAC.GTT AG.CT AC.GT AAAAC.GTTTT AG.CT AAAAC.GTTTT AG.CT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AC.GT AAAC.GTTT AAC.GTT AAAC.GTTT AAAC.GTTT AC.GT AAAT.ATTT AAAG.CTTT AAAAC.GTTTT AAC.GTT ACAGC.GCTGT ACAT.ATGT AG.CT AAAG.CTTT AGC.GCT AC.GT AG.CT AC.GT AAAC.GTTT AAG.CTT AG.CT AAGG.CCTT AT.AT AC.GT AT.AT AC.GT AAGG.CCTT AAAC.GTTT AC.GT AAAC.GTTT AAAG.CTTT AAAT.ATTT AGGG.CCCT AG.CT AAAC.GTTT AAAC.GTTT AAC.GTT AAAT.ATTT AAAC.GTTT AAT.ATT AC.GT ACAT.ATGT AAC.GTT AC.GT AAAT.ATTT ACAG.CTGT AT.AT AAAT.ATTT AT.AT AT.AT

2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2

12937922 12939678 13100893 13633030 13639999 13807177 13826658 14305857 14758476 15007497 15178808 15368445 15395978 16476170 16642783 16711323 16768766 16808589 17126872 17657161 17847703 18637232 19058799 19125574 19431722 19489753 19528946 19670762 19768046 20145865 20145865 20195213 20195213 20275035 20278841 20542414 20647405 20709009 20792860 20844818 21402505 21521115 21539685 21656216 21728568 21735197 21904530 22263244 22323137 22325849 22330315 22347604 22398311 22544666 22565814 22642282 22784452 22966435 22974074 23100531 23167309 23169608 23232549 23358454 23472939 23484991 23487958 23543154 23647672 23722325 23811409 23816030 23836000 24009611 24021898 24065004 24065958 24111063 24177542 24203252 24285149 24410539 24525832 24552785

12937931 12939692 13100910 13633048 13640010 13807187 13826669 14305881 14758487 15007511 15178821 15368460 15395994 16476181 16642806 16711343 16768776 16808602 17126881 17657189 17847725 18637247 19058811 19125589 19431750 19489764 19528965 19670772 19768069 20145879 20145879 20195229 20195229 20275062 20278853 20542428 20647427 20709035 20792874 20844838 21402527 21521127 21539718 21656233 21728602 21735216 21904542 22263260 22323150 22325861 22330326 22347624 22398330 22544680 22565826 22642300 22784479 22966454 22974085 23100541 23167331 23169622 23232565 23358472 23472954 23485014 23487972 23543164 23647693 23722352 23811422 23816056 23836030 24009643 24021916 24065025 24065971 24111074 24177564 24203274 24285180 24410552 24525842 24552795

5 3 4.5 4.75 6 5.5 3 12.5 6 3.75 7 5.33333 5.66667 6 4 5.25 5.5 4.66667 5 14.5 4.6 5.33333 6.5 8 5.8 6 4 5.5 6 3.75 3.75 4.25 4.25 5.6 6.5 3.75 7.66667 6.75 3.75 10.5 5.75 3.25 6.8 6 7 5 6.5 4.25 4.66667 6.5 6 10.5 5 5 6.5 4.75 14 10 6 5.5 5.75 3.75 8.5 4.75 4 6 3.75 5.5 5.5 7 4.66667 6.75 7.75 11 9.5 5.5 4.66667 6 5.75 5.75 16 3.5 5.5 5.5

. . . . . . . . . . . . . ENSSSCT00000014456 ENSSSCT00000014466 ENSSSCT00000014466 ENSSSCT00000014466 ENSSSCT00000014466 ENSSSCT00000014469 . . ENSSSCT00000014499 . . . . . . ENSSSCT00000014505 ENSSSCT00000027104 ENSSSCT00000031374 ENSSSCT00000027104 ENSSSCT00000031374 . . ENSSSCT00000014508 ENSSSCT00000014508 . . . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000010323 . . . . . . . . . . . . . . . . . .

. intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic MYBPC3 3'utr . intron . intron . intron . intron CKAP5 intron . intergenic . intergenic SYT13 3'utr . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic EXT2 intron HSD17B12 intron HSD17B12 intron HSD17B12 intron HSD17B12 intron . intergenic . intergenic TTC17 intron TTC17 intron . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . promoter . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic

0.194 0.15 . -0.249 -0.181 0.034 0.091 . . . . . . -0.075 0.178 . . 0.226 . 0.085 0.284 -0.151 -0.26 -0.167 -0.085 -0.011 -0.196 -0.518 0.129 -0.128 -0.128 1.138 1.138 . . 0.01 0.191 -0.13 . 0.573 . -0.149 0.069 -0.019 -0.298 -0.163 -0.15 -0.223 . . -0.167 0.336 -0.069 0.141 -0.152 0.033 . -0.074 . 0.076 -0.109 . . -0.158 0.065 0.158 0.284 0.635 . 0.051 -0.069 0.001 0.401 -0.042 -0.171 . . . 0.258 -0.241 -0.031 -0.168 . .

rs790475174 rs787171033 rs793849082 rs793513735 645041 rs7911 rs787183856 . . rs792448497 . 389546 rs7910 . 300987 rs7875 rs790142520 199734 rs7863 rs788694041 rs790199661 . rs787588165 rs790618398 rs792542651 911148 rs7867 . rs792388820 rs791650122 rs787286974 rs792382232 rs791048266 rs793521412 rs790892673 rs790892673 rs791328046 rs791328046 598695 rs7865 rs792326767 rs789043360 269465 rs7868 rs792226030 064387 rs7864 594316 rs7872 rs786611707 rs793606615 rs786955211 rs791240347 . rs792038706 808769 rs7880 781074 rs7912 rs700519962 rs789848479 rs789212618 rs792052065 308784 rs7915 783026 rs7887 rs788693119 rs793463545 . rs787785885 . rs696331745 rs787559129 rs788529504 970413 rs7907 372056 rs7864 054175 rs7900 rs793219963 rs702363069 087726 rs7887 rs793634634 998546 rs7930 rs791919475 362475 rs7887 rs793284283 519723 rs7914 . 675736 rs7899 290484 rs7891 . . 069302 rs7900 673929 rs7911 rs699640043 365087 rs7879 .

2 2 2 2 2 3 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 3 2 2 4 2 2 2 2 2 2 3 2 2 2 3 2 3 3 2 2 2 3 2 2 2 2 4 2 2 2 2 2 2 3 2 2 2 2 4 2 2 4 3 2 2 2 2 2

AC.GT AAAC.GTTT AAC.GTT AT.AT AC.GT AG.CT AAAC.GTTT AAAT.ATTT AAAC.GTTT AAAG.CTTT AT.AT AAAC.GTTT AG.CT AG.CT AAT.ATT AAC.GTT AATT.AATT AAC.GTT AAAC.GTTT ACAT.ATGT AAC.GTT AAAAC.GTTTT AAT.ATT AG.CT AGAGC.GCTCT AC.GT AG.CT AG.CT AG.CT AG.CT AG.CT AG.CT AG.CT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAT.ATT AAAC.GTTT AAAAT.ATTTT AAGG.CCTT AAAC.GTTT AAAAC.GTTTT AAACC.GGTTT AAAC.GTTT AG.CT AG.CT AAAAT.ATTTT AAG.CTT AAT.ATT AG.CT AG.CT ACCCC.GGGGT AAC.GTT AAAC.GTTT AT.AT AT.AT AATG.CATT AATG.CATT AAAC.GTTT AAAAAC.GTTTTT AG.CT AAAT.ATTT AAAC.GTTT AG.CT ATC.GAT AG.CT AAAC.GTTT AAAC.GTTT AAAT.ATTT AAAT.ATTT AAAAAG.CTTTTT AAAAT.ATTTT AATG.CATT AAAAC.GTTTT AAAAC.GTTTT

2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2

24634758 24654940 24663531 24734911 24906681 24936461 25136303 25346831 25429863 25660320 25727327 25762968 25768757 25856645 25902366 25907414 25953715 26012704 26048168 26234987 26817143 27390492 27434455 27861126 27924016 27973818 28166613 28166613 28166613 28166613 28166613 28166613 28166613 28201884 28201884 28201884 28201884 28201884 28201884 28201884 28201884 28201884 28261521 28268915 28432012 28506563 28590772 28600559 28605494 28807996 28963490 29059091 29088535 29136023 29266329 29429352 29623533 29725903 29793891 29892924 29966005 29988915 30342620 30503863 30503863 30524868 30524868 30538519 30702670 30757108 30779487 30819002 30888068 31130248 31312275 31717289 31717289 31955467 32030446 32317302 32420082 32507862 32558602 32558602

24634768 24654967 24663544 24734922 24906693 24936472 25136319 25346852 25429886 25660338 25727337 25762990 25768774 25856654 25902382 25907437 25953733 26012720 26048190 26235017 26817164 27390526 27434469 27861138 27924041 27973830 28166627 28166627 28166627 28166627 28166627 28166627 28166627 28201898 28201898 28201898 28201898 28201898 28201898 28201898 28201898 28201898 28261544 28268938 28432034 28506576 28590795 28600575 28605506 28808017 28963509 29059108 29088576 29136037 29266346 29429370 29623552 29725921 29793903 29892939 29966020 29988942 30342634 30503874 30503874 30524893 30524893 30538541 30702693 30757119 30779509 30819025 30888084 31130272 31312286 31717316 31717316 31955494 32030459 32317327 32420106 32507885 32558632 32558632

5.5 7 4.66667 6 6.5 6 4.25 5.5 6 4.75 5.5 5.75 9 5 5.66667 8 4.75 5.66667 5.75 7.75 7.33333 7 5 6.5 5.2 6.5 7.5 7.5 7.5 7.5 7.5 7.5 7.5 3.75 3.75 3.75 3.75 3.75 3.75 3.75 3.75 3.75 6 6 5.75 4.66667 6 3.4 3.25 5.5 4 3.6 10.5 7.5 9 3.8 6.66667 6.33333 6.5 8 3.2 9.33333 3.75 6 6 6.5 6.5 5.75 4 6 5.75 6 8.5 8.33333 6 7 7 7 3.5 4.33333 5 6 6.2 6.2

. . . . . . . . . . . . . . . . . . . . ENSSSCT00000014517 ENSSSCT00000014519 ENSSSCT00000014519 . ENSSSCT00000029479 . ENSSSCT00000035454 ENSSSCT00000034523 ENSSSCT00000036240 ENSSSCT00000034695 ENSSSCT00000033911 ENSSSCT00000033268 ENSSSCT00000014523 ENSSSCT00000033268 ENSSSCT00000036145 ENSSSCT00000035454 ENSSSCT00000034523 ENSSSCT00000036240 ENSSSCT00000034695 ENSSSCT00000035311 ENSSSCT00000014523 ENSSSCT00000033911 ENSSSCT00000035311 ENSSSCT00000035311 ENSSSCT00000014524 . . . . . ENSSSCT00000014529 ENSSSCT00000014529 ENSSSCT00000014529 ENSSSCT00000014529 . . ENSSSCT00000014537 ENSSSCT00000014537 ENSSSCT00000026025 . . . ENSSSCT00000029285 ENSSSCT00000014540 ENSSSCT00000025799 ENSSSCT00000014540 ENSSSCT00000025799 . ENSSSCT00000025907 ENSSSCT00000014541 . . . ENSSSCT00000030193 . ENSSSCT00000031770 ENSSSCT00000014547 . . . . . ENSSSCT00000014554 ENSSSCT00000036062

. intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic PRR5L intron LDLRAD3 intron LDLRAD3 intron . intergenic PAMR1 intron . intergenic CD44 intron CD44 intron CD44 intron CD44 intron CD44 intron CD44 intron CD44 intron CD44 intron CD44 intron CD44 intron CD44 intron CD44 intron CD44 intron CD44 intron CD44 intron CD44 intron CD44 intron CD44 intron PDHX intron . intergenic . intergenic . intergenic . intergenic . intergenic ABTB2 intron ABTB2 intron ABTB2 intron ABTB2 intron . intergenic . intergenic KIAA1549L intron KIAA1549L intron CD59 intron . intergenic . intergenic . intergenic DEPDC7 intron QSER1 intron QSER1 intron QSER1 intron QSER1 intron . intergenic CCDC73 intron EIF3M intron . intergenic . intergenic . intergenic . intron . intergenic ELP4 intron ELP4 intron . intergenic . intergenic . intergenic . intergenic . intergenic MPPED2 intron MPPED2 intron

. 0.152 0.068 -0.093 . -0.077 -0.016 -0.125 -0.298 0.119 -0.069 . . -0.039 -0.025 -0.006 . . -0.046 0.069 . -0.121 0.292 -0.061 -0.154 0.183 . . . . . . . 0.405 0.405 0.405 0.405 0.405 0.405 0.405 0.405 0.405 -0.042 0.036 0.298 0.23 0.082 -0.055 0.733 0.046 -0.107 . 0.368 -0.571 . 0.027 0.234 0.19 . 0.322 0.048 0.136 0.865 0.18 0.18 0.395 0.395 0.285 0.087 . -0.099 . 0.123 0.214 1.367 . . -0.024 . 0.229 0.498 -0.056 -0.021 -0.021

. rs786703297 489032 rs7872 rs788518775 rs704436561 . rs692357142 655484 rs7885 454862 rs7892 rs790127470 022542 rs7871 . rs790042714 . . 831780 rs7906 rs787936285 679476 rs7931 017986 rs7902 772865 rs7869 899738 rs7890 428487 rs7881 . rs792798150 rs787637939 rs694136434 rs791279472 rs791279472 rs791279472 rs791279472 rs791279472 rs791279472 rs791279472 rs790193027 rs790193027 rs790193027 rs790193027 rs790193027 rs790193027 rs790193027 rs790193027 rs790193027 356874 rs7882 rs790444986 rs789333835 299722 rs7929 412705 rs7862 rs792984128 . rs791527196 325698 rs7917 rs710182387 630879 rs7899 rs792778704 rs788061139 581976 rs7903 rs788784998 236388 rs7863 rs790487147 rs792281427 rs787748240 139091 rs7864 rs790305084 . . rs788315940 rs788315940 rs791915615 rs789310249 rs791537679 418464 rs7936 . . 804145 rs7915 rs790625389 931146 rs7913 931146 rs7913 rs793830208 rs788668316 912825 rs7872 rs786647060 435708 rs7892 rs792325053 rs792325053

2 2 2 3 2 2 2 3 2 2 2 2 2 3 2 3 2 2 2 2 3 2 3 3 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 4 4 2 2 2 2 2 2 2 3 2 2 2 2 2 3 2 2 2 2 2

AAAAC.GTTTT AAAAC.GTTTT AAAAC.GTTTT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AAG.CTT AG.CT AATG.CATT AC.GT AT.AT AAAG.CTTT AAT.ATT AAAC.GTTT AAAT.ATTT AAAAT.ATTTT AAAT.ATTT AAAAAC.GTTTTT AG.CT ACACAT.ATGTGT AAT.ATT AAT.ATT AAAAAT.ATTTTT AAAC.GTTT AATC.GATT AC.GT AAAC.GTTT AAT.ATT AAAC.GTTT AAAG.CTTT AT.AT AAAT.ATTT ACATAT.ATATGT AT.AT AAAC.GTTT AT.AT AAAC.GTTT AAAT.ATTT AT.AT AAAT.ATTT AT.AT AAAT.ATTT AT.AT AAAAAC.GTTTTT AAAAC.GTTTT ACATAT.ATATGT AC.GT ACAT.ATGT AGAT.ATCT AAAT.ATTT AC.GT AAT.ATT AG.CT AG.CT AAAG.CTTT AC.GT AAAC.GTTT AG.CT AT.AT ACAG.CTGT AAGG.CCTT AT.AT AAAC.GTTT AAT.ATT AAT.ATT AG.CT AAAAC.GTTTT AAC.GTT AAAAAC.GTTTTT AAAC.GTTT AC.GT AAAAC.GTTTT AT.AT AG.CT AAAT.ATTT AT.AT AGAT.ATCT AGAT.ATCT AG.CT AG.CT AG.CT AAT.ATT

2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2

32558602 32558602 32558602 32704823 32704823 32704823 32704823 32727902 32838956 32862319 32940259 33131486 33155428 33239858 33347908 33395755 33405201 33607194 33827922 34040144 34091900 34140527 34405037 34422282 34453428 34581005 35109931 35156922 35379982 35402151 35697375 35704437 35737512 36004194 36326977 36439351 36470508 36476051 36530541 36749498 36765193 36783478 36784628 37033928 37082758 37096764 37119786 37150451 37371445 37444458 37462893 37470219 37530338 37573681 37665238 37779684 37892566 38136185 38257734 38505591 38629598 38640877 38648511 38654604 38696303 38880844 38905770 39213829 39567551 39642026 39758712 39843336 39916704 40040428 40166670 40181829 40205395 40259263 40387860 40387860 40405351 40405351 40486040 40572490

32558632 32558632 32558632 32704836 32704836 32704836 32704836 32727923 32838975 32862331 32940295 33131509 33155439 33239893 33347928 33395769 33405223 33607210 33827952 34040170 34091913 34140549 34405052 34422304 34453445 34581023 35109943 35156932 35379996 35402163 35697389 35704448 35737521 36004220 36327000 36439362 36470522 36476063 36530562 36749524 36765208 36783503 36784639 37033941 37082772 37096786 37119803 37150496 37371463 37444470 37462904 37470246 37530351 37573696 37665256 37779693 37892578 38136195 38257750 38505608 38629607 38640894 38648556 38654613 38696325 38880858 38905787 39213839 39567566 39642042 39758730 39843349 39916714 40040470 40166680 40181843 40205416 40259286 40387890 40387890 40405381 40405381 40486055 40572502

6.2 6.2 6.2 4.66667 4.66667 4.66667 4.66667 7.33333 6.66667 6.5 9.25 12 6 9 7 3.75 5.75 3.4 7.75 4.5 7 3.83333 5.33333 7.66667 3 4.75 3.25 5.5 3.75 4.33333 3.75 3 5 6.75 4 6 3.75 6.5 5.5 6.75 8 6.5 6 3.5 7.5 3.83333 3.6 7.66667 9.5 3.25 3 7 7 5.33333 9.5 5 3.25 5.5 4.25 9 5 4.5 11.5 5 5.75 5 6 5.5 3.2 5.66667 3.16667 3.5 5.5 8.6 5.5 7.5 5.5 12 7.75 7.75 15.5 15.5 8 4.33333

ENSSSCT00000032813 ENSSSCT00000034692 ENSSSCT00000036405 ENSSSCT00000034692 ENSSSCT00000014554 ENSSSCT00000036405 ENSSSCT00000032813 . . ENSSSCT00000014555 . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000014567 . . . . . . . . . . . . . . . . . . ENSSSCT00000014569 ENSSSCT00000014569 ENSSSCT00000014569 ENSSSCT00000014569 . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000014572 ENSSSCT00000028769 ENSSSCT00000014572 ENSSSCT00000028769 . .

MPPED2 MPPED2 MPPED2 MPPED2 MPPED2 MPPED2 MPPED2 . . FSHB . . . . . . . . . . . . . . . . . . . . . . . . ANO3 . . . . . . . . . . . . . . . . . . LUZP2 LUZP2 LUZP2 LUZP2 . . . . . . . . . . . . . . . . . . . . . ANO5 ANO5 ANO5 ANO5 . .

intron intron intron intron intron intron intron intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intergenic intergenic

-0.021 -0.021 -0.021 0.168 0.168 0.168 0.168 -0.225 0.191 1.461 0.212 0.041 0.025 -0.042 0.008 . 0.041 -0.024 . . -0.267 0.092 0.138 0.041 -0.045 . 0.106 -0.07 . 0.209 -0.036 0.275 -0.012 . -0.12 . 0.034 -0.064 -0.012 . 0.001 . -0.087 . . 0.057 -0.002 -0.092 0.051 . . -0.001 -0.02 -0.112 0.295 -0.025 -0.458 -0.091 -0.125 -0.021 0.111 . 0.3 -0.123 0.034 -0.036 . . . -0.125 0.089 -0.125 0.709 -0.067 -0.157 -0.118 -0.09 0.055 0.107 0.107 0.187 0.187 -0.191 0.061

rs792325053 rs792325053 rs792325053 rs793695934 rs793695934 rs793695934 rs793695934 rs691529408 599366 rs7912 . rs790415396 rs786939664 rs792366696 047509 rs7863 rs792565862 rs793333968 . 599628 rs7930 rs788766892 rs788831542 rs793697055 rs791494872 rs788557921 . rs789635502 rs787673377 rs788359591 . rs786377814 rs791809524 rs788836812 rs787300903 rs788084764 rs789836927 rs793427155 . rs786450669 rs792845746 710620 rs7868 rs787612584 rs788153250 rs790105892 rs790419897 985189 rs7874 rs792761297 739848 rs7925 rs708161570 088792 rs7891 . 213434 rs7894 883437 rs7906 497394 rs7906 rs792809735 rs787776695 528994 rs7890 rs788346278 rs788624577 rs792350004 928919 rs7882 769428 rs7925 rs787284534 . 427019 rs7920 . rs793155632 rs789757604 rs786410690 945122 rs7900 rs787571648 rs787750791 rs792576376 rs789904957 rs788450267 rs793113403 rs793778328 . 298686 rs7907 rs788231479 rs787298168 rs787298168 rs786325683 rs786325683 rs787430733 .

2 2 2 3 3 3 3 2 2 2 3 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 3 2 3 2 2 2 2 2 2 3 2 4 2 2 2 2 3 2 2 2 2 3 2 2 2 2 2 2 2 2 3 2 4 4 2 2 2 2 2 3 2 4 4 2 2 2 2 2 2 2 2

AC.GT ATC.GAT AAAAC.GTTTT AC.GT AG.CT AAAT.ATTT AAC.GTT AAAT.ATTT AAAAT.ATTTT AC.GT AAAAC.GTTTT AAAG.CTTT AC.GT AC.GT AAAACC.GGTTTT AAAAAC.GTTTTT AC.GT AATG.CATT AAAC.GTTT AAC.GTT AC.GT AAC.GTT AATT.AATT AATT.AATT AT.AT AT.AT AACAC.GTGTT AAAC.GTTT AAAC.GTTT AG.CT AAAC.GTTT AAAAAG.CTTTTT ACAT.ATGT AAG.CTT AG.CT AAAT.ATTT AG.CT AAAAC.GTTTT AG.CT AG.CT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AAAT.ATTT AAC.GTT AC.GT AATC.GATT AC.GT ATCC.GGAT AT.AT AAC.GTT AAAC.GTTT AC.GT AAAC.GTTT AAC.GTT AC.GT AC.GT AAAC.GTTT AAAT.ATTT AAAT.ATTT AT.AT AC.GT AG.CT AATC.GATT AAGAG.CTCTT AATG.CATT ACAT.ATGT AAAAC.GTTTT AAAC.GTTT AAAAT.ATTTT AAC.GTT AAAC.GTTT AAAC.GTTT AC.GT AGG.CCT AAAAAG.CTTTTT AAC.GTT AAG.CTT AG.CT AAC.GTT AC.GT AG.CT AT.AT AGAT.ATCT

2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2

40625753 40674676 40751805 40811274 41154823 41195938 41238094 41301714 41378157 41599921 41856117 42032482 42564049 42627269 42804420 42950058 43048637 43267331 43328309 43328968 43511471 43646389 43705603 43705603 43909693 44031330 44072224 44120814 45022680 45105155 45116547 45281467 45640309 46107305 46456566 46515113 46541834 46596400 46774957 47099299 47114583 47311358 47325177 47419036 47512879 47545433 47610137 47776107 48428602 48574398 48622204 49218540 49584698 50056572 50222912 50267996 50330615 50979141 51474259 51474259 51554636 51560335 51567836 52083250 52112404 52118452 52235374 52451644 52471314 52617510 53145045 53162583 53386224 53427110 53881510 53912567 54358293 55242988 55275921 55341632 55955790 56014558 56019526 56158733

40625763 40674692 40751823 40811288 41154835 41195955 41238115 41301726 41378183 41599933 41856134 42032500 42564059 42627296 42804442 42950081 43048651 43267360 43328323 43328983 43511481 43646419 43705616 43705616 43909704 44031344 44072240 44120843 45022702 45105164 45116563 45281486 45640327 46107326 46456577 46515133 46541845 46596419 46774967 47099310 47114605 47311377 47325193 47419054 47512895 47545445 47610160 47776131 48428628 48574410 48622216 49218562 49584721 50056587 50222926 50268006 50330627 50979163 51474277 51474277 51554649 51560346 51567846 52083268 52112425 52118477 52235385 52451672 52471336 52617524 53145057 53162602 53386253 53427122 53881524 53912592 54358330 55243001 55275930 55341651 55955801 56014574 56019544 56158770

5.5 5.66667 3.8 7.5 6.5 4.5 7.33333 3.25 5.4 6.5 3.6 4.75 5.5 14 3.83333 4 7.5 7.5 3.75 5.33333 5.5 10.3333 3.5 3.5 6 7.5 3.4 7.5 5.75 5 4.25 3.33333 4.75 7.33333 6 5.25 6 4 5.5 6 5.75 5 3.4 4.75 5.66667 6.5 6 12.5 6.75 6.5 4.33333 5.75 12 4 5 5.5 6.5 5.75 4.75 4.75 7 6 5.5 4.75 4.4 6.5 3 5.8 5.75 3 4.33333 5 7.5 6.5 5 4.33333 12.6667 4.66667 5 6.66667 6 8.5 9.5 9.5

. . . . . . . . . . ENSSSCT00000014576 . . . . . . ENSSSCT00000014585 . . ENSSSCT00000014589 ENSSSCT00000014593 ENSSSCT00000014593 ENSSSCT00000014594 . . . . ENSSSCT00000024535 . . ENSSSCT00000014616 ENSSSCT00000024179 ENSSSCT00000014618 . . . . . ENSSSCT00000014620 ENSSSCT00000014620 . . . . . ENSSSCT00000014624 . ENSSSCT00000014630 ENSSSCT00000014630 . . . . . . ENSSSCT00000028332 . ENSSSCT00000025073 ENSSSCT00000014643 . . . . . . ENSSSCT00000029147 . . ENSSSCT00000024151 ENSSSCT00000014650 . . . ENSSSCT00000015283 ENSSSCT00000031062 ENSSSCT00000015274 . . . . . . .

. . . . . . . . . . PRMT3 . . . . . . CSRP3 . . PTPN5 UEVLD UEVLD LDHC . . . . PIK3C2A . . PLEKHA7 . . . . . . . INSC INSC . . . . . . . . . . . . . . . PARVA . GALNT18 GALNT18 . . . . . . MRVI1 . . . SWAP70 . . . ARF1 WNT3A SNAP47 . . . . . . .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intron intergenic intergenic intron intron intron intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intron intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intron intron intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic

-0.036 -0.028 . 0.698 . . 0.013 -0.178 -0.006 0.225 . . -0.147 -0.035 -0.024 . -0.02 0.007 . . -0.058 0.565 . . 0.035 0.054 . 0.058 . . . . 0.252 0.768 -0.015 . -0.07 -0.068 0.063 0.046 0.254 . . . . . 0.033 0.312 0.203 0.257 . 0.057 0.161 -0.013 -0.106 1.148 . . -0.169 -0.169 0.624 -0.043 -0.003 . 0.076 0.263 -0.072 0.169 . 0.42 0.064 . . . -0.217 0.161 . . . . . . . .

. rs786229736 . rs793061745 rs788289162 rs786734320 rs787827068 rs786967672 rs790486830 rs788934997 969646 rs7896 825060 rs7887 rs790698205 rs787512496 rs793445815 rs789930393 636561 rs7926 rs790169900 rs790549467 rs787369898 rs696679403 491926 rs7916 491773 rs7932 491773 rs7932 rs791904772 rs701407757 . rs787786485 302445 rs7929 rs789462345 rs793838474 622475 rs7935 rs788116404 181596 rs7906 . rs787915949 128283 rs7878 . 792247 rs7905 rs786889743 rs789422308 292347 rs7889 rs787021365 rs792640731 rs786335617 rs786388135 287644 rs7899 rs788035651 270787 rs7879 834126 rs7876 rs788813115 rs787848414 rs790828111 223066 rs7890 rs790193322 rs787235503 rs787080829 620273 rs7863 rs787220251 rs787220251 rs712854257 566895 rs7905 . 128156 rs7865 rs786388596 477519 rs7895 rs788682191 rs788497566 rs788678837 rs789780879 rs787993805 rs792264692 rs791191627 rs790649333 rs786621235 611513 rs7925 rs793263009 rs710751494 . rs789257646 rs791186255 rs789335851 rs789243194 rs790973178

3 2 2 3 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 3 3 2 2 2 2 2 3 2 2 2 2 2 2 2 2 3 3 2 2 2 2 2 2 2 2 3 2 2 2 6 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 4 2 3 2 2 2 3 3 2 2 2 2 2

AT.AT AT.AT AAT.ATT AG.CT AAT.ATT AAAT.ATTT AAC.GTT AAAC.GTTT AAAG.CTTT AC.GT AT.AT AC.GT AAAC.GTTT AAAC.GTTT AC.GT AG.CT AAAC.GTTT AT.AT AAAC.GTTT AATG.CATT AT.AT AAAG.CTTT AT.AT AAAAC.GTTTT AG.CT AC.GT AAAT.ATTT AAAAAT.ATTTTT AC.GT ACC.GGT AG.CT ATC.GAT AATG.CATT AAAC.GTTT AC.GT AAAAC.GTTTT AAAT.ATTT AG.CT AT.AT AAAAG.CTTTT AT.AT AG.CT AT.AT AAAAAC.GTTTTT AG.CT AAAC.GTTT AC.GT AAAT.ATTT AC.GT AAAC.GTTT AAAC.GTTT AAAG.CTTT AAAC.GTTT AC.GT AAAC.GTTT AAAC.GTTT AT.AT AAAT.ATTT AATG.CATT AAC.GTT AAAT.ATTT AC.GT AT.AT AAAC.GTTT AAAC.GTTT AATC.GATT AAC.GTT AT.AT AAAC.GTTT AAAAC.GTTTT AAAAT.ATTTT AAAAC.GTTTT AAAC.GTTT AAG.CTT AATT.AATT AAAT.ATTT AC.GT AAAT.ATTT AAAC.GTTT AAAAC.GTTTT AAAT.ATTT AG.CT ACC.GGT AT.AT

2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2

56497302 56539320 56593405 56603842 57242059 57278845 57837341 57850914 57946144 57961998 58137607 58591674 59053444 59295349 59322555 59447052 59799624 60114810 60118555 60284809 60422066 60543235 60594789 60729494 60901498 61028193 61028990 61037610 61126632 61169672 61441715 61480316 61606832 61855007 62162129 62544014 62835454 62861442 63268091 63929508 64039361 64123205 64331690 64832114 64834514 65212869 65443727 65496147 65875674 66178260 66637580 66667644 66747749 66888190 67231815 67231815 67294389 67320131 67448503 68116064 68366008 68412365 68442894 68496078 68496078 69370487 69704861 70108600 70179206 70554598 70977292 71667642 71668113 71873954 72172214 73208255 73330405 73922978 74165839 74851196 75442059 75575452 76097141 76154958

56497312 56539332 56593420 56603855 57242071 57278858 57837352 57850928 57946172 57962007 58137617 58591688 59053455 59295364 59322565 59447070 59799636 60114820 60118577 60284838 60422083 60543261 60594799 60729510 60901512 61028211 61029008 61037631 61126644 61169684 61441725 61480342 61606853 61855018 62162138 62544036 62835474 62861463 63268112 63929525 64039370 64123215 64331702 64832140 64834524 65212891 65443745 65496161 65875696 66178281 66637593 66667663 66747764 66888204 67231833 67231833 67294399 67320156 67448524 68116091 68366020 68412379 68442904 68496091 68496091 69370521 69704880 70108609 70179224 70554616 70977318 71667672 71668135 71873972 72172229 73208277 73330431 73922992 74165857 74851214 75442073 75575475 76097158 76154970

5.5 6.5 5.33333 7 4.33333 3.5 4 3.75 7.25 5 5.5 7.5 3 4 5.5 9.5 3.25 5.5 5.75 7.5 9 6.75 5.5 3.4 7.5 9.5 4.75 3.66667 6.5 4.33333 5.5 9 5.5 3 5 4.6 5.25 11 11 3.6 5 5.5 6.5 4.5 5.5 5.75 9.5 3.75 11.5 5.5 3.5 5 4 7.5 4.75 4.75 5.5 6.5 5.5 9.33333 3.25 7.5 5.5 3.5 3.5 8.75 6.66667 5 4.75 3.8 5.4 6.2 5.75 6.33333 4 5.75 13.5 3.75 4.75 3.8 3.75 12 6 6.5

. . . . . . . . . ENSSSCT00000015225 . . ENSSSCT00000015192 ENSSSCT00000015180 . ENSSSCT00000015176 ENSSSCT00000028010 . . ENSSSCT00000015149 . . . ENSSSCT00000015138 . ENSSSCT00000015134 . . . ENSSSCT00000015127 ENSSSCT00000022303 ENSSSCT00000022303 ENSSSCT00000024967 ENSSSCT00000027972 ENSSSCT00000015111 . . . . . . . . ENSSSCT00000015062 ENSSSCT00000015062 ENSSSCT00000015055 . . . . ENSSSCT00000015002 ENSSSCT00000015000 . . ENSSSCT00000014979 ENSSSCT00000022428 . . . . . . . ENSSSCT00000023717 ENSSSCT00000031182 . ENSSSCT00000014905 . . ENSSSCT00000014868 . . . . ENSSSCT00000014821 ENSSSCT00000014786 ENSSSCT00000026229 ENSSSCT00000014770 . ENSSSCT00000014758 . ENSSSCT00000014736 . .

. . . . . . . . . ZNF496 . . KXD1 IL12RB1 . SLC5A5 . . . CPAMD8 . . . C19orf44 . FAM32A . . . TPM4 . . CYP4F22 BRD4 SLC1A6 . . . . . . . . . . . . . . . ASNA1 TNPO2 . . MUC16 MUC16 . . . . . . . . . . ATG4D . . ELOF1 . . . . PEX11G GTF2F1 ACER1 SAFB2 . . . . . .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intron intron intergenic intron 3'utr intergenic intergenic intron intergenic intergenic intergenic intron intergenic promoter intergenic intergenic intergenic intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron promoter intergenic intergenic intergenic intergenic intron 3'utr intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic promoter promoter intergenic promoter intergenic intergenic promoter intergenic intergenic intergenic intergenic intron intron intron intron intergenic promoter intergenic intron intergenic intergenic

. . . . . . . . . . . 0.228 0.005 . -0.07 . 1.088 . . 0.058 . 0.241 . . . . . . . 0.051 . . 0.075 -0.161 0.062 . . . . . . . . . . . . . . . . 1.078 . . . . 0.088 . . . . . . . . . . . . . . . . . -0.266 . 1.208 -0.257 -0.181 -0.047 -0.363 -0.273 0.276 .

rs787061884 rs788941583 rs793160310 . . rs792690849 rs791301945 rs789979765 rs793064963 . . rs792840493 rs787380602 rs793250804 rs788989673 rs789009860 rs788385826 138374 rs7873 rs792384477 676571 rs7899 753160 rs7872 rs786376311 rs793708030 rs786724761 rs791299181 rs791655726 rs791339420 rs793627286 rs787155538 rs790206471 rs786532873 rs791914585 rs793488279 rs790672362 . 032589 rs7915 rs786491684 rs787770743 241598 rs7900 . rs791549002 rs786331144 rs789442224 655377 rs7877 183146 rs7916 rs791440616 rs792160984 rs786821994 rs789978101 625560 rs7903 . rs787238318 rs788584157 rs791266499 rs792249357 rs792249357 rs792228653 708952 rs7935 rs792794286 015772 rs7889 rs790759385 rs790725095 . 614361 rs7912 614361 rs7912 861812 rs7899 rs792223697 rs790254636 rs791726938 rs791556973 rs789174305 442309 rs7884 rs787261715 rs788214667 rs787648135 rs790611885 . rs789182128 rs791105334 095006 rs7894 705685 rs7894 rs709024084 rs791433085 rs790013745

2 2 2 3 3 2 2 2 2 4 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 3 2 2 3 3 2 3 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2

AT.AT AC.GT AAAC.GTTT AAT.ATT AC.GT AC.GT AC.GT AC.GT AT.AT ACC.GGT AAAAC.GTTTT AT.AT ACACC.GGTGT AAC.GTT AT.AT AAAC.GTTT AAAAT.ATTTT ACAT.ATGT AAAC.GTTT AATG.CATT AATG.CATT AAAAAC.GTTTTT AAAAAC.GTTTTT AAAT.ATTT AAAAAC.GTTTTT AC.GT AAAT.ATTT AC.GT AC.GT AATG.CATT AAAT.ATTT AAAC.GTTT AAAAT.ATTTT AC.GT AAAT.ATTT AAAAAT.ATTTTT AC.GT AAAC.GTTT AG.CT AAAC.GTTT AG.CT AAAAC.GTTTT AG.CT AAAC.GTTT AAAC.GTTT AAAC.GTTT AC.GT AG.CT AC.GT AAAAC.GTTTT AT.AT AAAT.ATTT AAC.GTT AAAT.ATTT AC.GT AG.CT AC.GT AT.AT AAAT.ATTT AAC.GTT AT.AT AAAC.GTTT AC.GT AC.GT AAC.GTT AAAC.GTTT AAAT.ATTT AAGG.CCTT AAC.GTT AG.CT AATG.CATT AG.CT AAAC.GTTT AT.AT AC.GT AAACT.AGTTT AG.CT AAC.GTT AAAC.GTTT AAAC.GTTT AG.CT AAAAC.GTTTT AAAG.CTTT AAAAAC.GTTTTT

2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2

76214689 76438694 76640508 76726473 77062837 77062837 77301862 78008670 79128389 79390833 79827599 80468689 80686084 81030289 81088736 81178626 81374445 81601829 81626905 81888748 81888748 81909913 81909913 81984420 82143179 83222756 83502688 83701703 83918692 84023259 84046121 84089836 84253916 84355216 84381459 84932166 85161144 85264685 85402032 85612810 85625340 85730335 85732065 85874522 86168138 86168138 86388142 86607526 86753344 86766964 87200724 87225047 87409879 87421000 87486794 87790729 87833451 88186628 88612825 88701669 89397825 89530464 89574345 89574345 89584478 89842459 90112473 90216853 90235938 90394059 90413912 90515084 90599333 91204065 91220433 91313187 91719240 91849064 91898225 91898225 92015956 92078654 92099944 92334753

76214700 76438716 76640526 76726489 77062848 77062848 77301875 78008683 79128411 79390854 79827632 80468702 80686098 81030302 81088752 81178641 81374463 81601849 81626927 81888764 81888764 81909939 81909939 81984433 82143205 83222766 83502711 83701717 83918702 84023287 84046134 84089852 84253940 84355226 84381480 84932188 85161153 85264704 85402042 85612829 85625349 85730352 85732079 85874545 86168164 86168164 86388183 86607535 86753354 86766999 87200736 87225064 87409895 87421014 87486803 87790741 87833464 88186639 88612840 88701688 89397839 89530486 89574357 89574357 89584494 89842492 90112491 90216869 90235953 90394074 90413928 90515094 90599347 91204083 91220459 91313202 91719250 91849078 91898244 91898244 92015967 92078683 92099965 92334771

6 11.5 4.75 5.66667 6 6 7 7 11.5 7.33333 6.8 7 3 4.66667 8.5 4 3.8 5.25 5.75 4.25 4.25 4.5 4.5 3.5 4.5 5.5 6 7.5 5.5 7.25 3.5 4.25 5 5.5 5.5 3.83333 5 5 5.5 5 5 3.6 7.5 6 6.75 6.75 21 5 5.5 7.2 6.5 4.5 5.66667 3.75 5 6.5 7 6 4 6.66667 7.5 5.75 6.5 6.5 5.66667 8.5 4.75 4.25 5.33333 8 4.25 5.5 3.75 9.5 13.5 3.2 5.5 5 5 5 6 6 5.5 3.16667

. . intergenic . . intergenic . . intergenic ENSSSCT00000031657 TMPRSS9 intron ENSSSCT00000028307 DOT1L intron ENSSSCT00000014701 DOT1L intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000015303 MAPK9 intron ENSSSCT00000015315 CANX intron . . intergenic ENSSSCT00000031469 ZNF354C intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000015329 RMND5B intron ENSSSCT00000015334 FAM193B intron ENSSSCT00000015329 RMND5B intron ENSSSCT00000015333 . promoter ENSSSCT00000015329 RMND5B intron ENSSSCT00000015341 NSD1 intron ENSSSCT00000015361 SIMC1 intron . . intergenic . . intergenic ENSSSCT00000026067 FCHO2 intron . . intergenic ENSSSCT00000015367 TMEM174 3'utr . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000015375 GFM2 intron . . intergenic . . intergenic ENSSSCT00000015379 . promoter ENSSSCT00000015379 . cds . . intergenic ENSSSCT00000015382 COL4A3BP intron ENSSSCT00000026755 COL4A3BP intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000015389 IQGAP2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000015399 PDE8B intron . . intergenic ENSSSCT00000015403 . intron ENSSSCT00000015403 . intron . . intergenic ENSSSCT00000015413 DMGDH intron ENSSSCT00000015413 DMGDH intron ENSSSCT00000015408 . intron ENSSSCT00000015413 DMGDH intron . . intergenic . . intergenic ENSSSCT00000024422 . intron . . intergenic ENSSSCT00000015420 . intron . . intergenic ENSSSCT00000015421 . intron . . intergenic ENSSSCT00000015430 MSH3 intron ENSSSCT00000015430 MSH3 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000015435 SSBP2 intron ENSSSCT00000023648 SSBP2 intron . . intergenic . . intergenic . . intergenic . . intergenic

. -0.161 -0.394 . . . . . . . . . -0.006 . . 0.277 0.259 . 0.063 0.364 0.364 . . . . 0.221 -0.093 -0.026 1.289 . 0 0.276 -0.173 -0.155 0.223 0.177 0.33 . . 0.024 0.162 0.216 . 0.366 0.286 0.286 0.178 0.088 0.152 0.082 0.128 -0.061 0.033 0.218 . 0.238 -0.242 0.121 0.28 0.131 . 0.239 0.152 0.152 0.043 0.149 0.005 . . 0.272 0.2 0.381 0.053 -0.22 0.067 0.128 0.198 . -0.048 -0.048 0.275 0.191 . 0.076

. rs788477340 rs786531180 169144 rs7870 rs793213130 rs793213130 937146 rs7921 rs787562270 rs789808125 771017 rs7864 . rs789857467 rs792169575 rs793556170 rs786636418 rs787730412 rs789484955 rs793072898 rs793437296 . . rs787430004 rs787430004 rs788988498 rs789750839 rs793007928 rs792192138 rs792321599 614250 rs7933 rs789452986 rs791594183 533570 rs7912 rs791377758 803880 rs7892 538047 rs7917 rs793413434 rs690172201 rs790850475 . 586149 rs7935 rs788862461 rs787552926 rs792939048 rs792600814 rs789718167 rs789718167 rs788988497 . rs788995052 099637 rs7888 rs788381465 rs788222439 799615 rs7894 rs787795306 rs792217597 rs786452778 rs788428941 rs791501331 rs788691457 rs789282523 rs793638485 rs793300985 rs789105050 rs789105050 rs787799650 rs789264074 736607 rs7910 rs787871955 425062 rs7878 424999 rs7930 rs790820804 . 794935 rs7904 rs789622819 rs790805030 rs792439605 . 920705 rs7910 rs789921958 rs789921958 060703 rs7932 rs792344482 . rs790728489

3 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 3 3 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 4 2 2 3 3 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 3 2 4 2 2 2 2 2 2 2

AG.CT AC.GT AAT.ATT AT.AT AC.GT ACAT.ATGT AAC.GTT AAAC.GTTT AG.CT AT.AT AT.AT AT.AT AT.AT AT.AT AT.AT AT.AT AAGAGG.CCTCT AT.AT AAAC.GTTT AAAAAC.GTTTTT AAAC.GTTT AAAC.GTTT AC.GT AATT.AATT AT.AT AAAT.ATTT AAAC.GTTT AT.AT AAAC.GTTT AC.GT AC.GT AAAT.ATTT AT.AT AC.GT AAAT.ATTT AC.GT AAAC.GTTT AAAAAC.GTTTTT AT.AT AAAT.ATTT AG.CT AAAAC.GTTTT AC.GT AAAC.GTTT AT.AT AAAAC.GTTTT AAAAC.GTTTT AC.GT AT.AT AAAG.CTTT AT.AT AAAG.CTTT AT.AT AC.GT AT.AT AAAAC.GTTTT AAAC.GTTT AAAAT.ATTTT AC.GT AAT.ATT AGGG.CCCT AAAT.ATTT AAT.ATT AC.GT AT.AT AC.GT AC.GT AT.AT AG.CT AAC.GTT AAC.GTT AG.CT AT.AT AC.GT AAT.ATT AAAAC.GTTTT AAAAG.CTTTT AAAAAC.GTTTTT AAAG.CTTT AC.GT AT.AT AAAT.ATTT AAAT.ATTT AAAC.GTTT

2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2

92794239 92900293 93391063 93589051 93641300 93665541 93700511 93774260 93780280 93839807 93839807 93839807 93839807 93839807 93839807 93839807 93992953 94021708 94424080 94428271 94504663 94609070 94720997 94944446 95124201 95594477 95822457 95931742 96125485 96210295 96604909 96615963 96910853 96921142 96947457 97013529 97198791 97298433 97473071 97804026 98289036 98311523 98498336 98570887 98584984 98863087 98863087 98937453 99683970 99982389 100350884 100683540 101240370 101250220 101263298 101338989 102559677 102646860 102738465 102808990 102865467 102882358 103418876 103730279 104286012 104476342 104479047 104518416 104780372 104812279 104851540 105072714 105146841 105423469 105429885 105447799 105576845 106289958 106295940 106356978 106377861 106944030 106944030 106976745

92794251 92900305 93391078 93589063 93641310 93665567 93700533 93774278 93780290 93839817 93839817 93839817 93839817 93839817 93839817 93839817 93992972 94021722 94424098 94428293 94504683 94609094 94721011 94944467 95124211 95594499 95822469 95931751 96125504 96210305 96604918 96615976 96910863 96921151 96947479 97013539 97198810 97298460 97473082 97804043 98289046 98311538 98498346 98570899 98584993 98863110 98863110 98937469 99683987 99982421 100350894 100683552 101240380 101250231 101263307 101339010 102559693 102646877 102738483 102809003 102865481 102882372 103418890 103730289 104286030 104476355 104479058 104518427 104780381 104812297 104851558 105072740 105146850 105423478 105429899 105447813 105576866 106289977 106295966 106356988 106377871 106944050 106944050 106976769

6.5 6.5 5.33333 6.5 5.5 6.75 7.66667 4.75 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5 3.33333 7.5 4.75 3.83333 5.25 6.25 7.5 5.5 5.5 5.75 3.25 5 5 5.5 5 3.5 5.5 5 5.75 5.5 5 4.66667 6 4.5 5.5 3.2 5.5 3.25 5 4.8 4.8 8.5 9 8.25 5.5 3.25 5.5 6 5 4.4 4.25 3.6 9.5 4.66667 3.75 3.75 5 5.5 9.5 7 6 6 5 6.33333 6.33333 13.5 5 5 5 3 4.4 3.33333 6.75 5.5 5.5 5.25 5.25 6.25

. . intergenic . . intergenic . . intergenic ENSSSCT00000015439 XRCC4 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000032588 VCAN intron ENSSSCT00000028327 VCAN intron ENSSSCT00000015440 VCAN intron ENSSSCT00000035607 VCAN intron ENSSSCT00000033743 VCAN intron ENSSSCT00000033299 VCAN intron ENSSSCT00000031327 VCAN intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000024141 . promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000015450 RASA1 intron . . intergenic ENSSSCT00000015452 TMEM161B intron ENSSSCT00000015452 TMEM161B intron . . intergenic . . intergenic . . intergenic ENSSSCT00000015454 MEF2C intron ENSSSCT00000015453 MEF2C intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000015467 . intron ENSSSCT00000015467 . intron ENSSSCT00000015467 . intron ENSSSCT00000015470 KIAA0825 intron ENSSSCT00000015470 KIAA0825 intron ENSSSCT00000015471 . intron . . intergenic ENSSSCT00000015473 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000015480 CAST intron ENSSSCT00000015481 CAST intron ENSSSCT00000015480 CAST intron

0.241 0.009 . . 0.015 0.367 . 0.019 0.154 -0.051 -0.051 -0.051 -0.051 -0.051 -0.051 -0.051 -0.132 -0.119 -0.101 -0.016 0.333 -0.038 -0.002 0.028 -0.011 0.107 -0.011 0.541 -0.043 . . . 0.292 0.14 -0.003 0.274 0.082 -0.241 0.123 -0.001 . 0.178 0.342 0.25 0.021 0.04 0.04 1.648 -0.101 -0.029 . 0.252 0.076 0.053 . . . 0.456 . -0.011 0.134 0.184 0.412 0.475 0.82 . . . . 0.189 . 0.055 0.199 . . . . . . . . -0.066 -0.066 0.107

503197 rs7905 rs788594790 . 243127 rs7893 rs788230938 982639 rs7927 750236 rs7882 . . rs789071097 rs789071097 rs789071097 rs789071097 rs789071097 rs789071097 rs789071097 rs791199710 . 550815 rs7927 406278 rs7906 . 971411 rs7918 rs790242543 rs787313320 rs790856814 504462 rs7923 484874 rs7895 rs790042797 723095 rs7937 596870 rs7906 rs792073559 . 871775 rs7893 rs793451378 rs788701061 rs789207491 224432 rs7868 rs789412756 rs792174805 rs789139482 . rs792071667 . 214674 rs7927 rs789813112 rs792802118 rs792802118 . rs786503094 239713 rs7880 rs786782754 . 729622 rs7915 rs787350983 rs787642481 401250 rs7925 rs787459404 234453 rs7923 rs788734592 rs788814048 rs786257739 062436 rs7905 rs790498589 . . rs791470938 rs791629040 rs793661848 . rs789456230 rs786734939 rs793481303 rs790705430 . . rs789099024 rs790369614 rs789590506 rs786528622 . 286416 rs7904 rs786874369 rs786874369 rs789069165

2 2 3 2 2 2 3 2 4 3 3 3 3 3 3 3 2 3 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 3 2 2 2 2 3 2 2 2 3 3 4 3 2 2 2 2 2 2 2 3 4 4 2 2 2 2 2 2 3 2 3 2 2 2 2 2 3 2 2 2 2

AAAC.GTTT AAAAG.CTTTT AAAAG.CTTTT AAC.GTT AT.AT AC.GT AC.GT AAAT.ATTT AT.AT AT.AT AT.AT AATT.AATT AC.GT AAAT.ATTT ACGT.ACGT AAGGGG.CCCCT AAAAC.GTTTT ACCT.AGGT AGAT.ATCT AC.GT AAAT.ATTT AAC.GTT AC.GT AG.CT AT.AT AAT.ATT AAAAAT.ATTTTT AAC.GTT AC.GT AT.AT AC.GT AAAAC.GTTTT AAT.ATT AAT.ATT AT.AT AAT.ATT AC.GT AG.CT AAAT.ATTT AAAAC.GTTTT AG.CT AT.AT AT.AT AAAC.GTTT AC.GT AAAAC.GTTTT AAAAAC.GTTTTT AAAC.GTTT ACAG.CTGT AT.AT AAAT.ATTT AAATC.GATTT AAAC.GTTT AC.GT AAGG.CCTT AAAAAT.ATTTTT AAAT.ATTT AG.CT AT.AT AT.AT AAAC.GTTT AC.GT AAAC.GTTT AT.AT AAG.CTT AAT.ATT AT.AT AAAG.CTTT AAAC.GTTT AAAC.GTTT AC.GT AAAT.ATTT AAAAC.GTTTT AT.AT AT.AT AAAAC.GTTTT AAC.GTT AAAC.GTTT AT.AT AC.GT AG.CT AAAAC.GTTTT AT.AT AAAAG.CTTTT

2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2

106976745 106998233 106998233 107410062 107448433 107490885 107767633 108047470 108050579 108125273 108282136 108398882 108403971 108461233 108508748 108614513 108783180 108794860 108963106 109196852 109203830 109261268 109320560 109326863 109343225 109465133 109666656 109844582 109855069 109911257 110005926 110124328 110295032 110315482 110453019 110502614 110653683 110672919 110732029 110819680 110834565 111187011 111400007 111401995 111577881 111633491 111710112 112210979 112278010 112630885 112674119 112707383 113005023 113390421 113469173 113505382 113533672 113543356 113647389 113843554 113870947 114458375 114596454 114638600 114935129 115160021 115623023 115670186 115692090 115777817 116107626 116130021 116180497 116212592 116366924 116444040 116775772 116819388 116826835 116843680 116949338 117031815 117141521 117392477

106976769 106998251 106998251 107410075 107448462 107490898 107767646 108047491 108050591 108125291 108282149 108398894 108403983 108461257 108508769 108614534 108783199 108794886 108963127 109196882 109203844 109261281 109320580 109326873 109343236 109465144 109666678 109844599 109855084 109911267 110005941 110124352 110295046 110315493 110453035 110502642 110653700 110672929 110732045 110819694 110834575 111187044 111400026 111402013 111577895 111633520 111710144 112210993 112278041 112630896 112674140 112707397 113005037 113390431 113469199 113505400 113533690 113543368 113647408 113843565 113870966 114458387 114596468 114638617 114935143 115160042 115623033 115670200 115692108 115777840 116107646 116130038 116180517 116212603 116366934 116444063 116775787 116819406 116826847 116843695 116949361 117031837 117141532 117392497

6.25 3.8 3.8 4.66667 15 7 7 5.5 6.5 9.5 7 3.25 6.5 6.25 5.5 3.66667 4 6.75 5.5 15.5 3.75 4.66667 10.5 5.5 6 4 3.83333 6 8 5.5 8 5 5 4 8.5 9.66667 9 5.5 4.25 3 5.5 17 10 4.75 7.5 6 5.5 3.75 8 6 5.5 3 3.75 5.5 6.75 3.16667 4.75 6.5 10 6 5 6.5 3.75 9 5 7.33333 5.5 3.75 4.75 6 10.5 4.5 4.2 6 5.5 4.8 5.33333 4.75 6.5 8 12 4.6 6 4.2

ENSSSCT00000015481 CAST intron ENSSSCT00000015480 CAST intron ENSSSCT00000015481 CAST intron ENSSSCT00000015485 LNPEP intron ENSSSCT00000015485 LNPEP intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000015492 ST8SIA4 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000023670 . intron ENSSSCT00000031964 PPIP5K2 intron ENSSSCT00000031964 PPIP5K2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

0.107 0.236 0.236 0.179 0.141 . 0.141 . . -0.009 -0.016 -0.108 . 0.045 . . 0.303 -0.01 0.218 0.138 0.204 0.025 . . . . -0.019 0.144 -0.257 . 0.045 . . . . 0.156 0.204 . 0.049 0.148 -0.058 . . . 0.121 . . 0.119 0.153 1.687 0.428 0.857 . 0.452 . . 0.225 -0.001 -0.177 . . 0.395 . 0.199 -0.064 0.084 -0.121 -0.072 -0.259 . -0.136 . . 0.352 0.051 -0.029 0.816 0.571 0.229 -0.16 0.7 . -0.059 0.023

rs789069165 . . rs789503939 . rs793469179 . 300352 rs7891 417475 rs7863 rs788003837 641808 rs7933 680442 rs7934 . rs792574788 rs793871794 707191 rs7935 rs787242763 920711 rs7869 rs791727519 rs788153958 rs789438488 rs790327634 . . . rs792273709 . 501371 rs7909 rs787768386 rs788327364 956729 rs7907 rs786738094 rs792729142 . rs793153185 rs788335240 rs788495580 . 727472 rs7885 rs789130615 . rs791974147 rs788637213 126486 rs7895 rs709236214 rs712449974 750976 rs7916 rs792861842 190365 rs7872 rs790445899 rs788079085 rs791207217 167889 rs7862 . 366436 rs7867 rs791835419 300061 rs7933 rs706240333 . rs786461627 rs788188893 398589 rs7934 rs789199428 . 043353 rs7898 419919 rs7866 rs792364414 . rs790793268 213259 rs7864 rs788652233 203877 rs6958 170123 rs7890 rs789209556 rs792500992 790338 rs7890 rs787324845 rs793193137 . rs789878250 rs793869426 rs787514192 . 979412 rs6999

2 2 2 2 2 4 3 2 2 2 2 2 3 2 2 2 2 2 2 3 2 2 4 2 3 2 2 2 2 2 2 2 2 2 2 2 4 4 2 2 4 2 2 2 4 2 2 2 2 4 2 2 2 3 2 2 2 5 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 4 2 3 2 2 2

AT.AT AAAAAC.GTTTTT AACAC.GTGTT AT.AT AAC.GTT AC.GT AC.GT AAAC.GTTT AATGG.CCATT AT.AT AAAT.ATTT AC.GT AAAAC.GTTTT AAAAC.GTTTT AT.AT AAT.ATT AAAC.GTTT AC.GT AT.AT AAAT.ATTT AC.GT AT.AT AAAC.GTTT AAAC.GTTT AAAAG.CTTTT AAAC.GTTT AC.GT AAAC.GTTT AC.GT AAACAC.GTGTTT AAAC.GTTT AAAAC.GTTTT AAAC.GTTT AAT.ATT AAAT.ATTT AT.AT AAAAC.GTTTT AAAC.GTTT AC.GT AC.GT AAAC.GTTT AC.GT AC.GT AC.GT AG.CT AC.GT AC.GT AG.CT AT.AT AAAC.GTTT AAAT.ATTT AG.CT AC.GT AT.AT AAAC.GTTT AT.AT AC.GT AAAAC.GTTTT AAC.GTT AT.AT AAC.GTT AAAG.CTTT AGAT.ATCT AAAC.GTTT AC.GT AAC.GTT AAAC.GTTT AAAC.GTTT AAC.GTT AG.CT AG.CT AAAAT.ATTTT AG.CT AAAAC.GTTTT AAAAC.GTTTT AAC.GTT AAC.GTT AAAC.GTTT AAC.GTT AAAC.GTTT AC.GT AC.GT AAAAC.GTTTT AGC.GCT

2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2

117640441 117970155 118035056 118202850 118224845 118469412 118469546 118672185 119040191 119071434 119098310 119121377 119159753 119166131 119179390 119317239 119387918 119514160 119566374 119699843 120182656 120665090 120689640 120695062 120754653 120837268 121219879 121308524 121399949 121444651 121496287 121504373 121715873 121824381 122120626 122654697 123057242 123574647 123610233 123865264 124082792 124148607 124148607 124148607 124196224 124522674 124608255 124672349 125114712 125168380 125315456 125334672 125535731 125539062 125674898 126022949 126173053 126173558 126179786 126179853 126327480 126620593 126876553 126933047 126992872 127041741 127234226 127354602 127412442 127482934 127597412 127665716 127865305 128473037 128473037 128478373 128478373 128573798 128677501 128708245 128753742 128755284 128845030 128964866

117640450 117970177 118035076 118202867 118224858 118469422 118469561 118672215 119040207 119071443 119098326 119121387 119159767 119166162 119179400 119317251 119387954 119514172 119566391 119699860 120182670 120665099 120689655 120695074 120754670 120837294 121219895 121308556 121399961 121444672 121496307 121504392 121715886 121824401 122120640 122654719 123057259 123574665 123610245 123865275 124082806 124148625 124148625 124148625 124196234 124522693 124608271 124672361 125114722 125168400 125315472 125334683 125535743 125539072 125674924 126022973 126173065 126173577 126179801 126179874 126327491 126620607 126876569 126933066 126992886 127041759 127234244 127354626 127412454 127482948 127597426 127665738 127865325 128473055 128473055 128478386 128478386 128573826 128677514 128708267 128753752 128755294 128845048 128964882

5 3.83333 4.2 9 4.66667 5.5 8 7.75 3.4 5 4.25 5.5 3 6.4 5.5 4.33333 9.25 6.5 9 4.5 7.5 5 4 3.25 3.6 6.75 8.5 8.25 6.5 3.66667 5.25 4 3.5 7 3.75 11.5 3.6 4.75 6.5 6 3.75 9.5 9.5 9.5 5.5 10 8.5 6.5 5.5 5.25 4.25 6 6.5 5.5 6.75 12.5 6.5 4 5.33333 11 4 3.75 4.25 5 7.5 6.33333 4.75 6.25 4.33333 7.5 7.5 4.6 10.5 3.8 3.8 4.66667 4.66667 7.25 4.66667 5.75 5.5 5.5 3.8 5.66667

. . . . . . . ENSSSCT00000024375 . . . . ENSSSCT00000015510 ENSSSCT00000015510 ENSSSCT00000015510 . . . . . . . . . . ENSSSCT00000015517 . ENSSSCT00000015519 ENSSSCT00000015522 . ENSSSCT00000024663 ENSSSCT00000024663 . . . ENSSSCT00000015529 . ENSSSCT00000015531 ENSSSCT00000015531 . . ENSSSCT00000032987 ENSSSCT00000015532 ENSSSCT00000033618 . . . . . ENSSSCT00000015541 ENSSSCT00000015541 ENSSSCT00000015541 . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000024571 ENSSSCT00000031873 ENSSSCT00000024571 ENSSSCT00000031873 . . . ENSSSCT00000025027 ENSSSCT00000025027 . .

. intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intron . intergenic . intergenic . intergenic . intergenic MAN2A1 intron MAN2A1 intron MAN2A1 intron . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic STARD4 intron . intergenic . intron DCP2 intron . intergenic REEP5 intron REEP5 intron . intergenic . intergenic . intergenic YTHDC2 intron . intergenic KCNN2 intron KCNN2 intron . intergenic . intergenic TRIM36 intron TRIM36 intron TRIM36 intron . intergenic . intergenic . intergenic . intergenic . intergenic COMMD10 intron COMMD10 intron COMMD10 3'utr . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic DMXL1 intron DMXL1 intron DMXL1 intron DMXL1 intron . intergenic . intergenic . intergenic HSD17B4 intron HSD17B4 intron . intergenic . intergenic

1.029 0.072 0.069 0.118 -0.049 0.03 0.036 0.056 0.177 -0.122 0.412 0.18 -0.165 1.006 0.041 0.252 0.057 0.113 0.065 . 0.228 0.025 1.202 . . 0.168 -0.022 -0.235 . . 0.022 0.141 -0.071 -0.028 . -0.523 . 0.066 -0.093 0.152 -0.007 0.551 0.551 0.551 -0.06 -0.103 0.721 . . . 0.113 0.277 -0.015 0.027 . -0.032 0.013 0.213 0.047 0.103 . . 0.056 -0.089 -0.09 -0.066 -0.067 -0.17 . -0.121 -0.133 -0.146 -0.091 3.213 3.213 0.21 0.21 0.334 0.084 0.032 0.124 0.312 0.082 0.219

rs790091226 . . rs786486354 735519 rs7863 rs791496726 rs793556738 rs793197428 rs789752835 rs786960014 rs793393784 rs792550630 . 086697 rs7936 rs786908687 726433 rs7918 954001 rs7864 rs793192548 . rs789752809 rs791183985 . 070989 rs7892 rs789230194 927333 rs7911 044825 rs7895 rs793759024 rs788608403 . rs792581952 754657 rs7917 546399 rs7886 641914 rs7867 830681 rs7910 rs787224512 rs786803952 rs793153801 120795 rs7886 rs792098484 rs791076455 rs786799441 . . . . rs705370534 rs789375819 396864 rs7884 . 057169 rs7902 . 880906 rs7876 052396 rs7899 rs788402560 849793 rs7874 rs792901839 rs788290583 rs787462176 rs792654605 rs790898190 . rs786673385 344900 rs7869 486249 rs7864 . rs788319300 rs790690697 834456 rs7937 . . rs793106507 rs793019019 319676 rs7905 . . rs793551464 rs793551464 rs790281105 rs789591912 459991 rs7862 rs790541007 rs788549768 rs792727439 rs791019146

2 2 2 2 2 3 2 2 2 2 2 3 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 4 2 2 2 2 4 4 4 4 3 3 2 3 2 2 2 2 2 2 2 2 2 2 4 3 2 2 2 3 3 2 3 3 4 4 2 2 2 2 2 2 3 2 2 2 2 2 2

AAAT.ATTT AAC.GTT AC.GT AC.GT AT.AT AAC.GTT AAAC.GTTT AAC.GTT AAAC.GTTT AAAT.ATTT AC.GT ACAT.ATGT AAAC.GTTT AG.CT AT.AT AATC.GATT AC.GT AAAC.GTTT AAAC.GTTT AAAT.ATTT AC.GT ACT.AGT AAC.GTT AAC.GTT AAAC.GTTT AC.GT AT.AT AT.AT AC.GT AAAT.ATTT AG.CT AAAG.CTTT AGAT.ATCT AC.GT AAAC.GTTT AAAAC.GTTTT AG.CT AC.GT AAC.GTT AT.AT AAAC.GTTT AAAAC.GTTTT AT.AT AG.CT AG.CT AAT.ATT AAAT.ATTT AAAT.ATTT AAAAAC.GTTTTT AAAC.GTTT AG.CT AT.AT AG.CT AAT.ATT AT.AT AG.CT AT.AT AT.AT AT.AT AC.GT AAAT.ATTT ACAT.ATGT AAAAC.GTTTT AAAAC.GTTTT AC.GT AAAC.GTTT ACAG.CTGT AT.AT AG.CT AAAT.ATTT AAAAC.GTTTT AAAC.GTTT AT.AT AG.CT AAAAT.ATTTT AC.GT AC.GT AC.GT AAAAC.GTTTT AAAAC.GTTTT AAC.GTT AAC.GTT AC.GT AC.GT

2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2

129408735 129556017 129693736 129701984 129708046 129980338 130187670 130258738 130269063 130375001 130579437 130658533 130790724 130878828 130968260 131004834 131028832 131238049 131333140 131363091 131422643 131616834 132021017 132256822 132270130 132284239 132429857 132509099 132731283 132834587 132859201 132893556 133000604 133428616 133439155 133692948 133799279 133953510 134035022 134173099 134210094 134360602 134404454 134856073 134876380 134954672 135010207 135010207 135040272 135051362 135280185 135503406 135525979 135675469 135697971 135807598 135820037 135862431 135892277 135972378 136043441 136129985 136276192 136784372 137125465 137280821 137348183 137364402 137814855 138210174 138250854 138451864 138455244 138581383 138744956 138766520 138773416 138796719 138840338 138840338 138841055 138841055 138897038 138897038

129408752 129556030 129693754 129702000 129708057 129980357 130187684 130258761 130269082 130375023 130579448 130658553 130790751 130878838 130968282 131004856 131028844 131238072 131333154 131363105 131422653 131616846 132021035 132256842 132270148 132284251 132429867 132509108 132731299 132834606 132859213 132893578 133000618 133428632 133439167 133692970 133799291 133953520 134035044 134173108 134210116 134360630 134404464 134856083 134876390 134954684 135010221 135010221 135040296 135051379 135280200 135503415 135525990 135675494 135697980 135807608 135820048 135862442 135892288 135972388 136043468 136129999 136276215 136784388 137125477 137280835 137348200 137364412 137814865 138210188 138250881 138451879 138455255 138581393 138744976 138766529 138773430 138796730 138840356 138840356 138841069 138841069 138897048 138897048

4.5 4.66667 9.5 8.5 6 6.66667 3.75 8 5 5.75 6 5.25 7 5.5 11.5 5.75 6.5 6 3.75 3.75 5.5 4.33333 6.33333 7 4.75 6.5 5.5 5 8.5 5 6.5 5.75 3.75 8.5 3.25 4.6 6.5 5.5 7.66667 5 5.75 5.8 5.5 5.5 5.5 4.33333 3.75 3.75 4.16667 4.5 8 5 6 8.66667 5 5.5 6 6 6 5.5 7 3.75 4.8 3.4 6.5 3.75 4.5 5.5 5.5 3.75 5.6 4 6 5.5 4.2 5 7.5 6 3.8 3.8 5 5 5.5 5.5

. . . . . . . . . . . . . . ENSSSCT00000015551 ENSSSCT00000015551 . . . . . ENSSSCT00000022941 . ENSSSCT00000015559 ENSSSCT00000015559 . ENSSSCT00000015560 . . . . . . . . . . . . . . . . . . ENSSSCT00000015567 ENSSSCT00000027284 ENSSSCT00000015564 . . ENSSSCT00000015569 . ENSSSCT00000015571 . . ENSSSCT00000015573 ENSSSCT00000015573 . . . . . . . ENSSSCT00000015578 . . . . . . . . . . . . . ENSSSCT00000029538 ENSSSCT00000015586 ENSSSCT00000029538 ENSSSCT00000015586 ENSSSCT00000029538 ENSSSCT00000015586

. . . . . . . . . . . . . . ZNF474 ZNF474 . . . . . SNX24 . CEP120 CEP120 . CSNK1G3 . . . . . . . . . . . . . . . . . . ALDH7A1 . PHAX . . 3-Mar . MEGF10 . . . . . . . . . . . SLC27A6 . . . . . . . . . . . . . LYRM7 LYRM7 LYRM7 LYRM7 LYRM7 LYRM7

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intron intergenic intron promoter intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron promoter promoter intergenic intergenic intron intergenic intron intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron

0.065 . -0.043 . 0.059 0.174 0.022 . -0.033 . . . 0.054 0.097 . 0.193 0.03 -0.011 0.239 -0.001 0.289 . 0.007 . -0.03 0.154 . . 0.627 . 0.611 . -0.062 0.057 0.62 0.3 -0.004 0.165 0.206 . 0.138 0.423 . 0.074 0.158 -0.206 . . . -0.176 0.042 0.16 0.157 0.163 0.633 0.237 0.079 . 0.127 0.15 0.136 . . . 0.155 -0.14 0.034 -0.033 -0.035 0.075 0.033 . 0.241 . . 0.164 . 0.231 0.008 0.008 . . -0.124 -0.124

rs789052992 rs790281040 rs699670189 rs790872116 rs792458306 rs787785534 447271 rs7871 020003 rs7894 116880 rs7876 rs788711845 rs792860786 818101 rs7914 rs793190127 . rs793046460 rs789209563 468330 rs7904 . rs787928283 rs792152902 rs793083329 . 047030 rs7887 rs792433916 rs788946824 . rs793095934 rs786234465 rs787127780 rs788475441 098701 rs7878 rs788594393 rs793361947 . rs787653517 . rs791389286 rs792346572 rs793574441 . 638492 rs7916 rs789286998 rs697954378 . rs790946789 . rs793780625 rs793780625 690454 rs7900 rs792041744 rs790987669 rs787549409 . rs789366242 rs786483060 . rs789643106 rs789299756 rs793047990 . 596195 rs7932 . 671546 rs7876 rs792637807 rs793052762 231962 rs7929 rs793696240 rs695934974 rs792619456 rs793813022 . . 838521 rs7910 . 592927 rs7915 044027 rs7868 rs693953193 rs788595361 860213 rs7918 860213 rs7918 rs704753358 rs704753358 . .

2 2 2 5 2 2 2 4 2 2 2 2 2 2 3 2 5 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 3 2 3 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 3 2 5 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2

AC.GT AC.GT AAAAC.GTTTT AC.GT AG.CT AC.GT AAAC.GTTT AT.AT AAC.GTT AAAT.ATTT AAAC.GTTT AT.AT AT.AT AT.AT ACGC.GCGT AG.CT AC.GT AC.GT AGAGG.CCTCT AC.GT AAC.GTT AAAT.ATTT AAAAG.CTTTT AT.AT AAT.ATT AT.AT AAAC.GTTT ACGC.GCGT AC.GT AC.GT ACCC.GGGT AG.CT AAAC.GTTT AGCCC.GGGCT AAG.CTT AG.CT AT.AT AAAG.CTTT AC.GT AC.GT AAAC.GTTT AT.AT AAAT.ATTT AAAG.CTTT AAAAAG.CTTTTT AAAAAC.GTTTTT AC.GT AAG.CTT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AAAAT.ATTTT AC.GT AT.AT ACAT.ATGT AAAT.ATTT AC.GT AG.CT AGG.CCT AAAAG.CTTTT AGG.CCT AAAC.GTTT AAAT.ATTT AAAC.GTTT AAAAT.ATTTT AC.GT AC.GT AAC.GTT AG.CT AG.CT AC.GT AAAT.ATTT AT.AT AG.CT AAAG.CTTT AC.GT AATG.CATT AC.GT AAAC.GTTT AGC.GCT AG.CT AAAAC.GTTTT AG.CT AAG.CTT

2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2

138965710 139033382 139122618 139162213 139255479 139288429 139601896 139785510 139825125 139837744 140525566 140539653 140805863 140805863 141353699 141556785 141579260 141608854 141792493 141876073 142127357 142538975 142830941 143209588 143211310 143563405 143635743 143995095 144158639 144170404 144268253 144404527 144611061 144783280 145076775 145129821 145152866 145488945 145596330 145605825 145799402 145809839 146250761 146263014 146469037 146830501 147077974 147158302 148012640 148097331 148166564 148183406 148275084 148695005 148790790 148834243 148919522 149317620 149383998 149630912 149716474 149769243 149778772 149855864 149864930 150049738 150105304 150405336 150460739 150673715 150725722 150891780 151022782 151038713 151044387 151088027 151214175 151368399 151399182 151439511 151480480 151645911 151855415 151987242

138965724 139033392 139122641 139162230 139255493 139288442 139601914 139785521 139825145 139837765 140525580 140539670 140805872 140805872 141353721 141556794 141579283 141608873 141792513 141876096 142127371 142538998 142830964 143209598 143211331 143563415 143635759 143995108 144158648 144170418 144268264 144404555 144611079 144783300 145076789 145129830 145152877 145488959 145596339 145605834 145799418 145809854 146250775 146263039 146469062 146830529 147077983 147158318 148012661 148097351 148166584 148183425 148275094 148695032 148790805 148834262 148919532 149317630 149384010 149630931 149716489 149769258 149778785 149855880 149864950 150049764 150105316 150405360 150460756 150673724 150725733 150891798 151022806 151038725 151044409 151088040 151214194 151368416 151399203 151439524 151480492 151645936 151855424 151987257

7.5 5.5 4.8 9 7.5 7 4.75 6 7 5.5 3.75 9 5 5 5.75 5 12 10 4.2 12 5 6 4.8 5.5 7.33333 5.5 4.25 3.5 5 7.5 3 14.5 4.75 4.2 5 5 6 3.75 5 5 4.25 8 3.75 6.5 4.33333 4.83333 5 5.66667 5.5 5.25 4.2 4 5.5 14 4 5 5.5 5.5 4.33333 4 5.33333 4 3.5 4.25 4.2 13.5 6.5 8.33333 9 5 6 4.75 12.5 6.5 5.75 7 5 9 5.5 4.66667 6.5 5.2 5 5.33333

. . intergenic ENSSSCT00000015589 . intron ENSSSCT00000015589 . intron . . intergenic . . intergenic ENSSSCT00000015591 . intron ENSSSCT00000015595 ACSL6 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000015606 KIF3A intron ENSSSCT00000015606 KIF3A promoter ENSSSCT00000015614 AFF4 promoter ENSSSCT00000025744 AFF4 promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000015628 SEC24A intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000015644 TRPC7 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000015666 CTNNA1 intron . . intergenic ENSSSCT00000031093 PAIP2 intron ENSSSCT00000015680 ECSCR intron ENSSSCT00000023543 PFDN1 intron . . intergenic ENSSSCT00000015694 . intron ENSSSCT00000015694 . intron ENSSSCT00000015698 . intron ENSSSCT00000030809 PCDHAC2 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000015724 DIAPH1 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000015732 RNF14 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000028925 FGF1 intron . . intergenic ENSSSCT00000015737 ARHGAP26 intron ENSSSCT00000015737 ARHGAP26 intron ENSSSCT00000015737 ARHGAP26 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000015739 NR3C1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

-0.131 0.069 -0.075 . 0.163 0.018 . . . 0.242 . 0.165 0.251 0.251 0.099 0.032 -0.135 -0.308 -0.231 -0.333 0.303 . -0.035 0.131 0.276 -0.076 -0.154 0.361 0.319 . 0.108 -0.078 -0.002 -0.195 -0.266 1.037 0.033 0.138 0.269 . 0.244 . 0.195 0.235 . . . 0.134 1.528 . 0.214 0.368 0.358 . 0.22 . . . . 0.29 . 0.228 0.105 0.027 . -0.026 0.088 . . -0.004 . 0.049 -0.132 . 0.071 -0.001 0.162 . 0.06 -0.144 0.028 . 0.215 0.11

rs789032086 rs789871950 rs786355878 rs791964182 rs789293520 573026 rs7882 rs786903236 427631 rs7932 rs791546835 rs788323812 463192 rs7930 121994 rs7911 rs790238897 rs790238897 rs793265536 rs788849095 rs789958594 181841 rs7863 rs708884046 . rs713701373 rs788718625 rs786737717 rs792095743 rs791277432 . rs792468617 695737 rs7888 153536 rs7936 rs792282596 rs793429257 174708 rs7123 rs789268881 rs791339273 534500 rs7863 rs787978768 rs792918444 105194 rs7901 rs793844919 rs788318125 rs786362690 rs790435166 . 377924 rs7886 rs789720401 462183 rs7920 487080 rs7878 880032 rs7894 282663 rs7899 rs792803139 rs790078730 rs789728703 171441 rs7878 839313 rs7885 . 784597 rs7921 rs791860784 rs789972976 rs792739653 rs788718474 rs790895960 rs790533865 . rs787246932 rs792540458 809766 rs7932 rs787173741 rs792715626 rs791930500 . rs702976154 rs791046372 rs790245049 rs702573682 223544 rs7863 rs788892891 rs788467673 791554 rs7931 415995 rs7886 . rs791113093 rs792729605 rs787653918 rs791961230

2 2 3 4 2 2 2 3 2 2 2 2 3 3 2 3 2 2 2 3 2 2 2 2 2 2 2 2 2 3 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 3 2 2 2 2 2 2 2 2

AAC.GTT AAAC.GTTT AAC.GTT AAAC.GTTT AAAC.GTTT AT.AT AAAC.GTTT AC.GT AAATT.AATTT AC.GT AG.CT AG.CT AAAAC.GTTTT AAAAG.CTTTT AAAAG.CTTTT AAAAG.CTTTT AT.AT AAT.ATT AAAC.GTTT AAAC.GTTT AAAC.GTTT AG.CT AAAC.GTTT AAAG.CTTT AG.CT AAC.GTT AG.CT AC.GT AC.GT ACAT.ATGT AC.GT AC.GT AC.GT AACAT.ATGTT AAAC.GTTT AT.AT AC.GT AG.CT AAAC.GTTT AAG.CTT AAAC.GTTT AAAC.GTTT AGC.GCT AT.AT AGAT.ATCT AG.CT AG.CT ATC.GAT AAAT.ATTT AAC.GTT AT.AT ACAT.ATGT AG.CT AC.GT AAG.CTT AT.AT AAAT.ATTT AT.AT AG.CT AAAC.GTTT AT.AT AT.AT AAC.GTT AC.GT AG.CT AAAG.CTTT AG.CT AAAAG.CTTTT AGGG.CCCT AC.GT AAAC.GTTT AAAC.GTTT AAAC.GTTT AGGG.CCCT AAAC.GTTT AAAT.ATTT AC.GT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AAAG.CTTT AAC.GTT AG.CT AAGGG.CCCTT

2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3

152346649 152383413 152584576 152662795 152744597 152814512 153038706 153236002 153248215 153267049 153310383 153465533 153824447 153839670 153839670 153839670 153958554 154110133 154167799 154191069 154256435 154266253 154322690 154340833 154459482 154739588 154864453 155208697 155452507 155472645 155489766 155575316 155588941 155597403 155732994 156075552 156105206 156531578 156628960 156674485 157587920 158579464 158650368 159104897 159117674 159126415 159148556 159152212 159280686 159309955 160211596 160428855 160438561 160654682 160902748 161194690 161196644 161277953 161284968 161319782 161507554 161621828 421468 2070057 2252647 2381908 2389474 3901535 4730915 4992914 5348211 5588626 5588626 5799868 5936249 7120854 7269250 7415010 7556314 7567839 8026757 8108749 9536768 9659541

152346662 152383433 152584594 152662809 152744617 152814522 153038723 153236023 153248231 153267060 153310401 153465543 153824469 153839687 153839687 153839687 153958564 154110154 154167821 154191092 154256449 154266263 154322703 154340847 154459491 154739600 154864464 155208710 155452521 155472658 155489776 155575329 155588951 155597434 155733008 156075561 156105220 156531592 156628974 156674496 157587943 158579482 158650385 159104920 159117688 159126426 159148568 159152229 159280704 159309971 160211607 160428867 160438575 160654697 160902789 161194704 161196670 161277962 161284983 161319812 161507563 161621839 421481 2070070 2252659 2381932 2389499 3901552 4730929 4992925 5348228 5588650 5588650 5799892 5936276 7120867 7269259 7415037 7556328 7567855 8026769 8108762 9536780 9659563

4.66667 5.25 6.33333 3.75 5.25 5.5 4.5 11 3.4 6 9.5 5.5 4.6 3.6 3.6 3.6 5.5 7.33333 5.75 6 3.75 5.5 3.5 3.75 5 4.33333 6 7 7.5 3.5 5.5 7 5.5 6.4 3.75 5 7.5 7.5 3.75 4 6 4.75 6 12 3.75 6 6.5 6 4.75 5.66667 6 3.25 7.5 8 14 7.5 6.75 5 8 7.75 5 6 4.66667 7 6.5 6.25 13 3.6 3.75 6 4.5 6.25 6.25 6.25 7 3.5 5 5.6 3.75 4.25 3.25 4.66667 6.5 4.6

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000015749 . intron ENSSSCT00000015749 . intron ENSSSCT00000029042 . intron ENSSSCT00000015750 . intron ENSSSCT00000015746 PLAC8L1 intron . . intergenic ENSSSCT00000015753 . intron . . intergenic . . intergenic . . intergenic ENSSSCT00000015755 TCERG1 intron ENSSSCT00000015755 TCERG1 intron ENSSSCT00000029561 PPP2R2B intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000015770 HTR4 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000008324BETA-ACTIN intron . . intergenic . . intergenic ENSSSCT00000008342 BAIAP2L1 cds ENSSSCT00000008342 BAIAP2L1 intron . . intergenic . . intergenic ENSSSCT00000008382 AZGP1 promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000008416 EPHB4 intron ENSSSCT00000008425 PRKRIP1 intron . . intergenic

. 0.071 0.496 -0.094 0.034 0.015 . -0.086 0.078 0.208 0.189 . . 0.743 0.743 0.743 0.104 . 0.26 -0.011 . 0.273 . 0.302 0.002 -0.277 0.087 -0.12 -0.012 0.209 0.899 -0.023 . 0.262 0.116 . . . . . -0.055 . -0.227 . . . . . -0.313 -0.032 . . . . . . . . . . . . . . -0.176 0.145 . . 3.528 . . 1.291 1.291 0.503 -0.057 . . . . . -0.079 0.028 . .

371629 rs7892 rs790968962 811435 rs7920 rs791051157 rs787353989 rs792944941 605424 rs7887 rs787974668 rs793143874 rs787667300 817188 rs7867 rs790502902 695187 rs7870 rs793731080 rs793731080 rs793731080 rs793321156 976295 rs7877 251836 rs7896 rs786911066 323982 rs7871 rs787124101 874530 rs7899 rs790086387 rs791124767 970453 rs7930 rs705091475 rs786869060 622545 rs7892 000342 rs7904 rs787801380 532968 rs7869 . rs788273394 rs787102492 rs788140328 916009 rs7925 rs791793665 rs788210107 rs788331031 575922 rs7893 rs787404224 rs791733688 rs793826477 . rs791231361 rs792282056 rs788712173 rs789576600 rs790244465 774187 rs7933 . . rs788953566 . rs793506435 rs793602640 . . rs697877376 481225 rs7913 rs793083876 rs792696310 . 422959 rs7903 rs789902690 563174 rs7883 . 077865 rs7933 rs787180760 rs790199766 . . 327022 rs7926 770928 rs7907 912620 rs7901 . rs787523280 rs789508326 rs792469810 rs786852086 rs788231299 rs793549770 rs792378961

2 3 2 2 3 3 2 4 2 2 2 3 2 2 2 2 3 2 2 2 2 3 3 2 4 3 2 7 4 2 2 4 3 2 2 2 2 2 2 2 2 2 2 2 2 3 3 2 2 2 4 2 2 3 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 3 2 2 2 2 2 3 2 4 2

AAAT.ATTT AATG.CATT AAAG.CTTT AAT.ATT AC.GT AT.AT AAAC.GTTT AAAC.GTTT AC.GT AC.GT AAAT.ATTT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAAT.ATTTT AG.CT AC.GT AG.CT AAAC.GTTT AGGG.CCCT AAAC.GTTT AC.GT AC.GT AAAT.ATTT AAAAT.ATTTT AAAAC.GTTTT AAC.GTT AAAC.GTTT AC.GT AAT.ATT AAAAG.CTTTT AC.GT AGAT.ATCT AAT.ATT AC.GT AAAT.ATTT AT.AT AT.AT AGGG.CCCT AAAAG.CTTTT AAAC.GTTT AG.CT AG.CT AC.GT AAT.ATT AC.GT AC.GT AC.GT AC.GT AT.AT AC.GT AAAAC.GTTTT ATCC.GGAT AC.GT AG.CT AATC.GATT AG.CT AAAC.GTTT AC.GT AC.GT AAAG.CTTT AAAT.ATTT AC.GT AAAC.GTTT AC.GT AAAC.GTTT AG.CT ACAG.CTGT AG.CT AAAC.GTTT AAAC.GTTT AAAT.ATTT ACGC.GCGT ACGC.GCGT ACGC.GCGT ACGC.GCGT AC.GT AG.CT AAAG.CTTT AG.CT AT.AT AC.GT

3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3

9664587 10000883 10141694 10170258 10563415 10639362 10660585 10919799 10934382 10934382 10972510 11044661 11411341 11483100 11483100 11483100 11803008 11843728 12083600 12123359 12573637 13127848 13428765 13437166 13489359 13545020 13615722 13802802 13846771 14145001 14274603 14302613 14310373 14327850 14967463 15177160 15192148 15210826 15227122 15238314 15247293 15315160 15326604 15366819 15374810 15487909 15851165 15855741 16023423 16023901 16157984 16166135 16200725 16220706 16234161 16344376 16626607 16653874 16801434 16857923 16995043 17000390 17008622 17252712 17258013 17292878 17334831 17511891 17650992 17850137 17911904 18627694 19029919 19172558 19437258 19437258 19437258 19437258 19675246 20005785 20404346 20441038 20681897 20684382

9664601 10000901 10141713 10170273 10563427 10639372 10660607 10919817 10934408 10934408 10972526 11044677 11411355 11483117 11483117 11483117 11803027 11843739 12083616 12123370 12573655 13127862 13428776 13437177 13489378 13545035 13615737 13802819 13846785 14145019 14274613 14302626 14310399 14327879 14967481 15177180 15192160 15210837 15227154 15238326 15247306 15315180 15326625 15366833 15374824 15487927 15851178 15855754 16023435 16023918 16157993 16166144 16200735 16220729 16234185 16344386 16626621 16653900 16801446 16857942 16995053 17000413 17008636 17252734 17258026 17292892 17334842 17511909 17651002 17850155 17911918 18627725 19029941 19172580 19437269 19437269 19437269 19437269 19675260 20005801 20404376 20441051 20681908 20684396

3.75 4.75 5 5.33333 6.5 5.5 5.75 4.75 13.5 13.5 4.25 3.4 3.75 4.5 4.5 4.5 4 6 8.5 6 4.75 3.75 3 6 10 4 3.2 3.6 5 4.75 5.5 4.66667 5.4 15 4.75 7 6.5 3 16.5 6.5 3.5 4.2 5.5 7.5 7.5 9.5 4.66667 7 6.5 9 5 5 5.5 4.8 6.25 5.5 7.5 6.75 6.5 5 5.5 12 3.75 5.75 7 3.75 6 4.75 5.5 4.75 7.5 8 5.75 5.75 3 3 3 3 7.5 8.5 7.75 7 6 7.5

ENSSSCT00000024358 . promoter . . intergenic . . intergenic . . intergenic ENSSSCT00000008451 BCL7B intron . . intergenic ENSSSCT00000008456 WBSCR22 intron . . intergenic ENSSSCT00000032354 . intron ENSSSCT00000025955 LIMK1 promoter . . intergenic ENSSSCT00000028458 LAT2 intron . . intergenic ENSSSCT00000031896 GTF2I intron ENSSSCT00000030268 GTF2I intron ENSSSCT00000008466 GTF2I intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000008475 . intron ENSSSCT00000008475 . intron ENSSSCT00000008475 . intron ENSSSCT00000008475 . intron . . intergenic . . intergenic . . intergenic ENSSSCT00000008478 . intron ENSSSCT00000008480 . intron . . intergenic . . intergenic . . intergenic ENSSSCT00000025455 VKORC1L1 intron ENSSSCT00000025455 VKORC1L1 intron ENSSSCT00000025455 VKORC1L1 intron ENSSSCT00000027523 ZNF713 intron ENSSSCT00000027523 ZNF713 intron ENSSSCT00000008498 14-Sep intron . . intergenic ENSSSCT00000008507 PRSS8 intron . . intergenic ENSSSCT00000008519 STX1B intron . . intergenic ENSSSCT00000028946 KCTD13 promoter ENSSSCT00000008560 XPO6 intron ENSSSCT00000026157 GSG1L intron ENSSSCT00000032927 KIAA0556 intron ENSSSCT00000008563 KIAA0556 intron ENSSSCT00000034865 KIAA0556 intron ENSSSCT00000036362 KIAA0556 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

. . . . . . -0.101 -0.305 0.335 0.335 . . . -0.146 -0.146 -0.146 0.094 -0.06 0.005 . 0.282 -0.097 0.365 -0.171 . . 0.209 0.251 0.059 0.256 -0.017 . -0.216 -0.102 . 0.081 0.106 0.043 0.036 0.149 0.002 0.188 0.055 -0.135 0.635 0.591 . 0.166 -0.185 -0.026 0.181 . -0.134 0.175 . -0.152 -0.103 0.308 . . -0.029 . 0.011 . . 1.029 . -0.008 . 0.209 0.04 0.058 0.139 0.604 -0.079 -0.079 -0.079 -0.079 -0.445 0.22 . -0.107 . -0.434

072750 rs7898 rs786541958 rs786767143 rs790090480 . 017783 rs7918 rs792096315 rs793846557 367184 rs7887 367184 rs7887 017798 rs7863 999638 rs7918 rs787738819 190096 rs7901 190096 rs7901 190096 rs7901 rs788260334 rs791683513 267192 rs7933 . rs792556219 131810 rs7906 rs787549328 rs788567036 381813 rs7907 rs791911327 rs791838821 722377 rs7901 915694 rs7892 596860 rs7927 rs786807599 rs713251305 rs787304370 rs791399923 219854 rs7889 649306 rs7915 rs790747702 298011 rs7928 rs691205448 771331 rs7882 334746 rs7884 rs786909290 rs792960491 rs788551964 rs791028179 rs787842560 855772 rs7909 rs786235528 . rs792734795 . rs788679775 . rs792100248 rs790520415 rs786248095 . 175387 rs7876 . rs792463429 . rs790405007 rs789078869 rs793329212 . rs790027683 rs786717932 rs792308175 222220 rs7865 rs791566213 rs791765405 rs793706001 rs793264463 rs790301307 rs790825949 rs790825949 rs790825949 rs790825949 . rs792289629 . rs791525193 . rs711639571

2 2 3 3 2 2 2 2 2 2 2 2 2 3 3 3 2 2 2 3 3 2 2 2 3 2 2 2 2 2 3 2 2 5 2 2 8 2 2 2 2 2 2 3 2 3 2 3 2 3 2 2 2 2 2 2 3 2 2 3 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2

AG.CT AC.GT AAAAG.CTTTT AC.GT AGAT.ATCT AC.GT AT.AT ATCC.GGAT AAAAC.GTTTT AAG.CTT AG.CT AAAAAC.GTTTTT AATG.CATT AG.CT AAAC.GTTT AG.CT ACTC.GAGT AAC.GTT AC.GT AC.GT AAAAT.ATTTT AT.AT AAAT.ATTT AAG.CTT AAC.GTT AAC.GTT AAAG.CTTT AAAC.GTTT AAAT.ATTT AT.AT AAC.GTT AT.AT AAAC.GTTT AAAAT.ATTTT AAC.GTT AC.GT AAAC.GTTT AAAT.ATTT AAAC.GTTT AG.CT AC.GT AG.CT AGG.CCT AAGG.CCTT AT.AT AC.GT AAAC.GTTT AC.GT AAAC.GTTT AAAC.GTTT AG.CT AC.GT AC.GT AG.CT AAAC.GTTT AT.AT AAAAC.GTTTT AAT.ATT AACC.GGTT AC.GT ATCC.GGAT AAAC.GTTT AGG.CCT AG.CT AAAAAG.CTTTTT AAACC.GGTTT AC.GT AC.GT AC.GT AAAT.ATTT AAAG.CTTT AGC.GCT AAAC.GTTT AG.CT AAAAC.GTTTT ACTC.GAGT AAAGC.GCTTT AG.CT AAAAT.ATTTT AG.CT AAAC.GTTT ACAG.CTGT AC.GT AACC.GGTT

3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3

20885265 21299709 21429644 21471162 21476940 21705823 22853768 23720360 23800485 23873231 23881449 24150513 24198505 24289209 24520932 24719016 25154164 25350401 25479381 25689287 25745686 25749741 26072642 26081905 26133293 26299352 26522382 26760369 26761175 26794927 27072563 27210055 27286736 27325161 27334977 27449948 27573131 27769523 27946124 28179473 28228085 28404420 28441500 28450891 28577166 28934139 28938708 29037345 29178366 29179281 29290568 29366014 29514832 29638967 30094814 30140590 30386599 30670742 30771432 30805483 30807557 30814789 31076364 31189647 31313871 31336903 32032502 32403270 32524095 32581781 32968036 33183314 33220407 33269693 33351631 33611925 33775902 33880947 34438321 34653544 34886000 34894962 34991972 35206388

20885280 21299720 21429663 21471178 21476957 21705837 22853779 23720397 23800501 23873247 23881459 24150534 24198533 24289223 24520946 24719032 25154182 25350413 25479394 25689300 25745703 25749769 26072672 26081917 26133309 26299370 26522400 26760387 26761193 26794936 27072575 27210064 27286761 27325183 27334990 27449961 27573157 27769549 27946147 28179502 28228095 28404432 28441514 28450940 28577178 28934164 28938729 29037359 29178390 29179299 29290581 29366035 29514843 29638979 30094829 30140600 30386622 30670762 30771455 30805502 30807574 30814809 31076378 31189659 31313894 31336929 32032511 32403290 32524105 32581803 32968051 33183326 33220430 33269707 33351652 33611938 33775922 33880959 34438336 34653562 34886018 34894981 34991985 35206410

8 6 4 8.5 4.5 7.5 6 9.5 3.4 5.66667 5.5 3.66667 7.25 7.5 3.75 8.5 4.75 4.33333 7 7 3.6 14.5 7.75 4.33333 5.66667 6.33333 4.75 4.75 4.75 5 4.33333 5 6.5 4.6 4.66667 7 6.75 6.75 6 15 5.5 6.5 5 12.5 6.5 13 5.5 7.5 6.25 4.75 7 11 6 6.5 4 5.5 4.8 7 6 10 4.5 5.25 5 6.5 4 5.4 5 10.5 5.5 5.75 4 4.33333 6 7.5 4.4 3.5 4.2 6.5 3.2 9.5 4.75 5 7 5.75

. . . . . . ENSSSCT00000008581 ENSSSCT00000008587 ENSSSCT00000008587 . . ENSSSCT00000030167 . ENSSSCT00000008589 . ENSSSCT00000008595 ENSSSCT00000008597 ENSSSCT00000008598 ENSSSCT00000008598 . . . ENSSSCT00000024527 ENSSSCT00000027442 . . . . . . ENSSSCT00000020027 ENSSSCT00000031474 . . . . . ENSSSCT00000008627 . . . . . . . . . ENSSSCT00000008628 . . . . ENSSSCT00000028273 ENSSSCT00000008633 ENSSSCT00000027014 ENSSSCT00000027014 . . . . . . . . . . . . ENSSSCT00000008655 . . ENSSSCT00000008661 . . ENSSSCT00000032425 . ENSSSCT00000008663 . ENSSSCT00000029316 ENSSSCT00000008668 . . . .

. . . . . . CACNG3 HS3ST2 HS3ST2 . . METTL9 . EEF2K . . . . . . . . THUMPD1 ACSM4 . . . . . . U6 . . . . . . . . . . . . . . . . . . . . . CPPED1 PARN . . . . . . . . . . . . . . . . . . . . ATF7IP2 . GRIN2A . C16orf72 ABAT . . . .

intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intron intergenic 3'utr intergenic intron intron intron intron intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic promoter intron intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intron intergenic intergenic intron intergenic intron intergenic intron intron intergenic intergenic intergenic intergenic

0.853 -0.065 . 0.045 -0.249 0.012 . 0.084 0.153 -0.149 . 0.353 -0.07 0.004 0.416 0.083 . . . . 0.384 0.089 0.098 -0.028 0.008 . -0.042 . . 0.07 . -0.174 0.158 . . -0.074 . -0.365 0.674 -0.095 . -0.145 -0.094 . 0.098 . -0.983 . . . 0.13 . -0.345 -0.071 -0.009 0.098 . -0.03 -0.141 -0.004 . 0.045 0.015 -0.098 0.06 0.044 0.266 . . . 0.027 -0.025 . -0.243 0.174 -0.187 -0.051 -0.025 . 0.035 . 0.089 . 0.26

. rs789187820 050629 rs7862 632552 rs7922 384429 rs7932 654309 rs7896 rs789162769 rs789846499 rs788131476 467760 rs7922 364613 rs7934 rs790661451 . rs787948656 270773 rs7929 225340 rs7884 rs787839936 751127 rs7863 rs791544974 . rs792133166 rs793766056 rs791150587 rs793186876 rs791972632 151860 rs7866 572452 rs7888 507133 rs7916 . rs789435071 355487 rs7926 rs790200791 rs792723982 rs790342853 rs787408074 . rs787659662 284007 rs7933 938130 rs7929 312233 rs7878 rs790570479 206218 rs7907 rs787824609 rs788078843 rs787879683 rs789737939 334358 rs7916 rs790442665 198267 rs7913 106248 rs7877 rs787818520 . . rs787390643 rs788019543 rs791475370 rs790239337 rs791856306 rs793059327 . 969000 rs7899 035118 rs7862 467215 rs7930 . rs787631771 040136 rs7891 rs791211044 . rs787640796 341057 rs7917 rs787680043 rs790736425 020660 rs7935 . rs790991063 . rs790099937 rs790923279 . rs788823649 rs790255667 rs791418228 058010 rs7892 rs793015582

2 2 2 3 2 4 2 2 2 2 3 2 2 2 2 2 2 2 2 3 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 3 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 4 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 4 2

AAAAC.GTTTT AAAAC.GTTTT AAAAT.ATTTT AAC.GTT AAAAG.CTTTT AAC.GTT AAT.ATT AAAAT.ATTTT AAGG.CCTT AAAC.GTTT ATC.GAT AG.CT AAT.ATT AAAC.GTTT AC.GT AC.GT AC.GT AT.AT AAG.CTT AC.GT ACATC.GATGT AC.GT AAAAAG.CTTTTT AC.GT AG.CT AT.AT AAC.GTT AGGG.CCCT AC.GT AC.GT AAAT.ATTT AATT.AATT AAAC.GTTT AT.AT AC.GT AC.GT AC.GT AC.GT AC.GT AC.GT AG.CT AAAAC.GTTTT AAAT.ATTT AAG.CTT AAAC.GTTT AAG.CTT AAAG.CTTT AAAAAC.GTTTTT AG.CT AC.GT AAAC.GTTT AAAC.GTTT ACC.GGT ACACCC.GGGTG AT.AT AAAAAG.CTTTTT AGG.CCT AAG.CTT AAC.GTT AAAAAC.GTTTTT AC.GT ATCC.GGAT AAAT.ATTT AC.GT AAAC.GTTT AAAAC.GTTTT AC.GT AG.CT AC.GT AAAAAT.ATTTTT AT.AT AT.AT AC.GT AG.CT AAAT.ATTT AC.GT AAAC.GTTT AAAAC.GTTTT ACAT.ATGT AAAG.CTTT AG.CT AG.CT ACAT.ATGT ACAT.ATGT

3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3

35229566 35415965 35657350 35861948 35976741 36010165 36018170 36305892 36308918 36313848 36344317 36413067 36418357 36453247 36518940 36584149 36629444 36901880 37064554 37101013 37111945 37221424 37314258 37508089 37680015 37695929 38269718 39273108 39567975 39567975 40978406 41139093 41831579 43124368 43263445 43364100 43364100 43398485 43398485 44380830 44619480 44776485 44862459 45054399 45200304 45376215 45719859 45772649 45776894 46227628 46317255 46317255 46343203 46343356 46454856 46466184 46543670 46736828 47137836 47244252 47330896 47544227 47753442 47839040 47921676 48322355 48427019 48483892 49002914 49079112 49137966 49291910 49323756 49554941 49637014 49658190 49766228 49894382 50304543 50367811 50400716 50624389 50861754 50967932

35229588 35415990 35657370 35861964 35976764 36010181 36018185 36305913 36308941 36313862 36344348 36413076 36418371 36453273 36518951 36584183 36629456 36901894 37064573 37101029 37111962 37221446 37314275 37508100 37680037 37695938 38269731 39273120 39567987 39567987 40978422 41139118 41831595 43124386 43263457 43364113 43364113 43398494 43398494 44380840 44619495 44776523 44862480 45054410 45200335 45376264 45719885 45772684 45776904 46227641 46317273 46317273 46343221 46343379 46454869 46466208 46543684 46736840 47137854 47244273 47330908 47544250 47753473 47839051 47921695 48322384 48427031 48483901 49002932 49079132 49137978 49291921 49323773 49554952 49637026 49658216 49766246 49894408 50304565 50367828 50400731 50624406 50861765 50967949

4.6 5.2 4.2 5.66667 4.8 5.66667 5.33333 4.4 6 3.75 10.6667 5 5 6.75 6 17.5 6.5 7.5 6.66667 8.5 3.6 11.5 3 6 11.5 5 4.66667 3.25 6.5 6.5 4.25 6.5 4.25 9.5 6.5 7 7 5 5 5.5 8 7.8 5.5 4 8 16.6667 6.75 6 5.5 7 4.75 4.75 6.33333 4 7 4.16667 5 4.33333 6.33333 3.66667 6.5 6 8 6 5 6 6.5 5 9.5 3.5 6.5 6 9 6 3.25 13.5 4.75 5.4 5.75 4.5 8 9 3 4.5

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000008677 RBFOX1 intron ENSSSCT00000008677 RBFOX1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000008714 CREBBP intron ENSSSCT00000034723 CREBBP intron ENSSSCT00000008742 LUC7L intron . . intergenic ENSSSCT00000008789 IFT140 intron . . intergenic ENSSSCT00000008843 CENPP intron ENSSSCT00000008843 CENPP intron ENSSSCT00000008845 ASPN intron ENSSSCT00000008843 CENPP intron ENSSSCT00000032452 ECM2 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000019914 ssc-let-7a-2 promoter . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000008872 ZC3H8 intron ENSSSCT00000008872 ZC3H8 intron ENSSSCT00000008877 . intron ENSSSCT00000008877 . intron ENSSSCT00000008879 . intron ENSSSCT00000008877 . intron ENSSSCT00000008877 . intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000029914 . intron ENSSSCT00000023794 . intron ENSSSCT00000008884 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000008895 KCNIP3 intron ENSSSCT00000008896 . intron ENSSSCT00000008901 . intron ENSSSCT00000008901 . intron ENSSSCT00000008909 STARD7 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000008912 CCDC138 intron ENSSSCT00000008912 CCDC138 intron . . intergenic ENSSSCT00000008915 GCC2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

0.062 0.116 0.03 . -0.195 0.334 0.115 -0.187 -0.171 -0.196 0.02 0.261 -0.245 0.077 -0.051 -0.48 . -0.265 -0.692 0.102 -0.02 -0.275 0.115 -0.736 0.118 . -0.287 0.03 . . . . . . 0.879 0.175 0.175 0.031 0.031 . -0.095 . -0.037 . . . 0.254 . 0.401 . 0.669 0.669 . . -0.092 -0.097 . -0.271 0.15 . 0.09 0.065 . . . -0.174 0.149 -0.226 -0.211 . 0.282 . . . . . . 0.558 0.038 -0.426 0.199 0.068 0.183 .

rs786707448 rs789634035 738337 rs7924 600461 rs7881 rs792163064 rs790134000 rs791617795 rs698640738 rs792092927 rs789018803 rs707885805 . . rs789134916 rs790434773 rs787805291 227677 rs7933 . rs792070993 rs788336016 rs793607077 . 744785 rs7892 . rs787100346 rs793716337 rs788255600 . . . rs789534264 rs790643325 rs792505824 . . . . . . rs793551974 rs792135547 rs790332319 rs789989135 rs793647955 rs789256224 . 878292 rs7914 rs788036463 rs788013580 775253 rs7908 rs787334354 rs787334354 rs786881947 rs788904938 rs789471132 rs790782182 . rs788354279 rs789818528 rs786403932 . rs790772041 362933 rs7872 982401 rs7912 055803 rs7908 449725 rs7893 rs787682158 rs791175603 487355 rs7918 rs787794978 302349 rs7891 . rs788761719 rs789609597 rs790812391 rs790603422 . 521655 rs7901 rs787681339 rs793437954 rs786359354 rs787087650 rs791489285 rs791331351

2 2 2 2 2 2 2 2 3 3 2 2 3 2 3 4 2 2 3 2 2 4 2 3 4 2 2 2 4 4 2 2 2 3 3 2 2 2 2 2 2 2 2 2 2 3 2 2 2 3 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 3 2 2 2 2 5 2 2 2 3 2 3 2 2 2 2 2 2

AC.GT AT.AT AAAG.CTTT AAG.CTT AAAAG.CTTTT AC.GT AAAC.GTTT AAT.ATT AT.AT AT.AT AAAC.GTTT AAC.GTT AG.CT AT.AT AG.CT AAAAC.GTTTT AC.GT AAAC.GTTT AAC.GTT AG.CT AAAC.GTTT AAC.GTT AAT.ATT AAAC.GTTT AC.GT AC.GT AC.GT AG.CT AG.CT AC.GT AAAC.GTTT AC.GT AG.CT AAGG.CCTT AAAAT.ATTTT AAAAAC.GTTTTT AAAC.GTTT AAC.GTT AC.GT AG.CT AC.GT ACAT.ATGT AGG.CCT AC.GT AC.GT AAAAAG.CTTTTT AC.GT AT.AT AGG.CCT AT.AT ATC.GAT AAAC.GTTT AATG.CATT AG.CT AAAC.GTTT AAAAG.CTTTT AT.AT AAAAAC.GTTTTT AG.CT AAAC.GTTT AAAACC.GGTTTT AAAAC.GTTTT AAAAAC.GTTTTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AACAAT.ATTGTT AAC.GTT AAC.GTT AG.CT AG.CT AG.CT AG.CT AC.GT AAAAG.CTTTT AT.AT AAAT.ATTT AG.CT AT.AT AAT.ATT AAAC.GTTT AC.GT AAAT.ATTT

3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3

51157921 51289471 51308956 51365551 51417486 51616839 51778026 52606556 52677256 52695888 52854901 52875396 52907797 52951117 53137205 53182752 53367359 53373699 53494785 53728655 53904980 53944724 53955352 54001602 54255721 54255721 54255721 54276543 54448366 54627913 54676165 54684357 54781714 54790454 54797534 54838716 54890500 54972216 55396430 55672673 55759184 55871369 56007554 56312439 56323814 56446123 56684223 56782197 56850868 56939026 56966119 56966421 56993116 57188074 57239155 57492965 57655239 57776240 57893469 57944128 57997941 58405220 58828318 59148350 59148350 59148350 59477044 59508393 60247356 60394187 60621097 60621097 60621097 60621097 60780895 60818602 60966749 61170368 61192762 61460580 61719636 61726263 61751027 62012551

51157932 51289482 51308975 51365562 51417508 51616849 51778042 52606567 52677272 52695900 52854919 52875413 52907809 52951135 53137217 53182776 53367370 53373722 53494797 53728679 53905002 53944737 53955372 54001620 54255743 54255743 54255743 54276553 54448375 54627936 54676182 54684368 54781725 54790465 54797552 54838741 54890511 54972235 55396446 55672687 55759206 55871393 56007565 56312451 56323828 56446142 56684233 56782206 56850883 56939036 56966140 56966461 56993143 57188087 57239183 57492998 57655261 57776267 57893479 57944163 57997960 58405261 58828342 59148366 59148366 59148366 59477056 59508420 60247382 60394203 60621108 60621108 60621108 60621108 60780907 60818626 60966761 61170394 61192788 61460590 61719648 61726277 61751039 62012567

6 6 5 4 4.6 5.5 4.25 4 8.5 6.5 4.75 6 6.5 9.5 6.5 5 6 6 4.33333 12.5 5.75 4.66667 7 4.75 11.5 11.5 11.5 5.5 5 12 4.5 6 6 3 3.8 4.33333 3 6.66667 8.5 7.5 11.5 6.25 4 6.5 7.5 3.33333 5.5 5 5.33333 5.5 7.33333 10.25 7 7 7.25 6.8 11.5 4.66667 5.5 9 3.33333 8.4 4.16667 4.25 4.25 4.25 3.25 4.66667 9 5.66667 6 6 6 6 6.5 5 6.5 6.75 13.5 5.5 4.33333 3.75 6.5 4.25

. . . . . ENSSSCT00000008924 . . . . . . . . . . . . . . ENSSSCT00000008927 ENSSSCT00000008928 . ENSSSCT00000008930 ENSSSCT00000008934 ENSSSCT00000034710 ENSSSCT00000034786 . ENSSSCT00000008936 . . . . . . . . . ENSSSCT00000008942 . ENSSSCT00000008947 ENSSSCT00000008948 ENSSSCT00000008948 . . . . ENSSSCT00000008955 ENSSSCT00000008955 ENSSSCT00000008955 ENSSSCT00000008955 ENSSSCT00000008955 ENSSSCT00000008955 ENSSSCT00000008955 . ENSSSCT00000008958 ENSSSCT00000024738 ENSSSCT00000008965 . . . . . ENSSSCT00000035625 ENSSSCT00000036079 ENSSSCT00000008972 ENSSSCT00000008980 . . . ENSSSCT00000033509 ENSSSCT00000008994 ENSSSCT00000033653 ENSSSCT00000034821 . ENSSSCT00000008997 ENSSSCT00000031530 . . ENSSSCT00000030815 . ENSSSCT00000025660 . .

. . . . . FHL2 . . . . . . . . . . . . . . TMEM182 MFSD9 . NHE-2 IL18RAP IL18RAP IL18RAP . IL1RL1 . . . . . . . . . RFX8 . RPL31 . . . . . . . . . . . . . . REV1 LYG2 TSGA10 . . . . . ZAP70 ZAP70 ZAP70 . . . . CD8B CD8B CD8B CD8B . RMND5A . . . IMMT . . . .

intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intron intron intron intron intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intron intron intron intergenic intergenic intergenic intergenic intron intron intron intron intron intron intron intergenic intron intron cds intergenic intergenic intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intron intron intron intron intergenic intron intron intergenic intergenic intron intergenic intron intergenic intergenic

. -0.04 -0.473 . -0.026 . 0.096 . . -0.243 0.055 . -0.09 0.057 -0.033 -0.067 -0.081 0.123 0.357 -0.168 . -0.084 . 0.073 -0.365 -0.365 -0.365 0.106 . . . . -0.259 -0.069 . 0.111 . -0.021 . 0.208 . -0.258 0.181 . 0.11 . -0.104 -0.592 0.075 0.435 0.061 0.331 -0.361 . -0.03 2.45 0.091 0.376 0.008 . -0.177 . 0.05 . . . . 0.372 -0.313 . -0.079 -0.079 -0.079 -0.079 . . 0.111 . 0.106 . . 0.078 0.083 .

618597 rs7883 rs792759189 rs789508718 rs793497040 rs791219867 rs792211351 rs790676461 . rs786972748 . rs793032999 rs790457937 . rs792120594 . rs788260723 rs790354451 279091 rs7927 134074 rs7881 rs788381517 rs788979679 rs789383230 . rs788645005 rs692554221 rs692554221 rs692554221 . rs786523167 rs787754077 641931 rs7933 . 016343 rs7870 . 677792 rs7886 809547 rs7911 . 054675 rs7923 rs786278722 rs793790178 500325 rs7887 rs786951017 . rs697944266 549971 rs7931 . . . 320037 rs7900 694984 rs7897 rs786283077 rs791188348 rs786733285 rs793736078 rs789803412 . rs787313547 rs791797830 . rs788853730 . . rs790796831 rs792618811 rs792618811 rs792618811 958375 rs7909 rs703238455 719431 rs7882 rs791882021 rs790723495 rs790723495 rs790723495 rs790723495 rs789917204 rs789515303 rs788521123 . rs791475660 rs788101578 . 741180 rs7871 rs792328867 rs786225079

3 2 2 2 2 2 2 2 2 2 2 2 3 2 3 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 5 2 5 3 2 4 3 3 3 3 2 2 2 3 3 2 3 4 3 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 3 2 2 2 2 2 3 2 2 2

AAAAT.ATTTT AG.CT AAAC.GTTT AAAG.CTTT AAAC.GTTT AC.GT AC.GT AC.GT ACAT.ATGT AT.AT AAAT.ATTT AAAC.GTTT AATC.GATT AT.AT AAAC.GTTT AAAAT.ATTTT AT.AT AT.AT AC.GT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AG.CT AC.GT AAAAT.ATTTT AT.AT AAAC.GTTT AT.AT AAAC.GTTT AC.GT AAC.GTT AAAC.GTTT AT.AT AAT.ATT AAAG.CTTT AAAT.ATTT AAGGG.CCCTT AT.AT AAT.ATT AAC.GTT AAC.GTT AG.CT AC.GT AAGC.GCTT AAAAG.CTTTT AG.CT AC.GT AG.CT AT.AT AAG.CTT AAATG.CATTT AAAC.GTTT AAAC.GTTT AG.CT AAATT.AATTT AAAC.GTTT AG.CT ATC.GAT AT.AT AAAT.ATTT AAAC.GTTT AT.AT AC.GT AAG.CTT AT.AT AAAT.ATTT AC.GT AT.AT AGAT.ATCT AAAAT.ATTTT AAAC.GTTT AC.GT AAC.GTT AT.AT AAC.GTT AAAAC.GTTTT AAAC.GTTT AAAAT.ATTTT AG.CT AT.AT AC.GT AAAAAG.CTTTTT AAAC.GTTT AAAC.GTTT

3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3

62034309 62158668 62197861 62388137 62424214 62606985 62708769 62885802 62915694 63005707 63033490 63066351 63377320 63411806 63723823 63801213 63875483 64003820 64049338 64105405 64109806 64145656 64314197 64322258 64361948 64437162 64486732 64604258 64607089 64618223 64641821 64832020 64871988 64952556 64955818 65052452 65064666 65111738 65140787 65271276 65318156 65372924 65545824 65991358 66013207 66023278 66066209 66301903 66345080 66479207 66538817 66549757 66691237 66703078 66847623 66876555 67075708 67109453 67293740 67302455 67802583 67827215 67870100 67918573 68046143 68325851 68512803 68570459 68877765 68968644 69020704 69066934 69279689 69433931 69489962 69556808 69656919 69694724 69845193 69873491 69883953 69919100 70037428 70044614

62034332 62158692 62197881 62388151 62424230 62606995 62708787 62885816 62915707 63005716 63033509 63066367 63377339 63411820 63723837 63801230 63875495 64003831 64049348 64105423 64109820 64145685 64314209 64322272 64361969 64437171 64486762 64604275 64607113 64618232 64641837 64832047 64872010 64952568 64955832 65052466 65064683 65111747 65140798 65271289 65318173 65372937 65545835 65991374 66013224 66023311 66066222 66301912 66345101 66479219 66538836 66549791 66691261 66703111 66847637 66876573 67075720 67109468 67293750 67302469 67802601 67827227 67870110 67918584 68046155 68325876 68512817 68570481 68877779 68968662 69020728 69066947 69279712 69433950 69489978 69556828 69656944 69694746 69845211 69873506 69883976 69919121 70037447 70044636

4.8 12.5 5.25 3.75 4.25 5.5 9.5 7.5 3.5 5 5 4.25 5 7.5 3.75 3.6 6.5 6 5.5 4.75 3.75 6 6.5 7.5 4.4 5 7.75 9 6.25 5 5.66667 7 11.5 4.33333 3.75 3.75 3.6 5 4 4.66667 6 7 6 4.25 3.6 17 7 5 11 4.33333 4 8.75 6.25 17 3 4.75 6.5 5.33333 5.5 3.75 4.75 6.5 5.5 4 6.5 6.5 7.5 11.5 3.75 3.8 6.25 7 8 10 5.66667 4.2 6.5 4.6 9.5 8 12 3.66667 5 5.75

ENSSSCT00000009013 ATOH8 intron . . intergenic ENSSSCT00000027775 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009036 . intron ENSSSCT00000009036 . intron ENSSSCT00000009036 . intron ENSSSCT00000009036 . intron ENSSSCT00000009036 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009040 CTNNA2 intron ENSSSCT00000009040 CTNNA2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

-0.211 -0.014 . . -0.433 0.115 0.639 0.029 -0.205 . 0.197 0.168 . 0.031 . 0.112 0.03 0.144 . . -0.032 . -0.131 -0.414 . 0.071 -0.146 -0.159 -0.081 0.095 -0.123 -0.097 -0.234 0.104 0.157 -0.063 -0.108 . . 0.047 -0.18 . . . -0.044 . 0.375 -0.109 0.123 0.459 0.296 . 0.273 1.389 . -0.417 -0.071 -0.197 -0.051 -0.183 . . -0.097 . -0.21 0.063 . . -0.065 . . . 0.043 -0.061 -0.023 . 0.163 . -0.001 -0.047 0.027 -0.213 -0.038 0.002

rs788129432 rs791868086 rs793274522 750588 rs7063 rs789249119 . rs791220368 913649 rs7868 rs789643936 rs786279021 rs790112302 . 969170 rs7896 rs790257207 . 275565 rs7929 rs792602480 rs787053880 rs791366628 rs788470526 rs790924686 rs790005156 . 480767 rs7891 . rs793094715 822037 rs7881 241871 rs7881 rs791750228 . rs790558409 701306 rs7866 643966 rs7113 . . rs791337103 rs789823809 . rs788845407 rs788720885 rs791266817 . . rs708737788 rs793597171 180219 rs7896 rs789498643 . 141255 rs7892 rs786301574 486422 rs7921 290029 rs7912 rs791375308 rs786468125 . rs790869342 571551 rs7892 516488 rs7904 rs789090427 342682 rs7923 rs787541453 rs792353205 rs788179133 rs787638043 rs791667769 rs788849747 659054 rs7879 rs790775884 rs791900267 . . . rs789843558 rs787157579 rs789741366 rs792117877 234521 rs7878 rs790508552 rs793818419 rs787000701 rs787973599 888662 rs7926 . rs692417613

2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 8 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 3 2 4 3 2 2 4 2 4 2 2 2 3 2 4 2 2 2 2 2 2 2 4 3 2 3 2 2 2 2 2 4 3 2 2 3 2 4 2 4 2 2 2 3 2

AAC.GTT AAT.ATT AGAT.ATCT AAC.GTT AAT.ATT AAAT.ATTT AC.GT AGG.CCT AAAC.GTTT AC.GT AT.AT AAAG.CTTT AAAG.CTTT AATG.CATT AAG.CTT AAG.CTT AT.AT AT.AT AAC.GTT AC.GT AAAT.ATTT AC.GT AAAC.GTTT AC.GT AG.CT AC.GT AC.GT AC.GT AG.CT ATC.GAT AAAC.GTTT AAAAC.GTTTT AC.GT AAAG.CTTT ATC.GAT AT.AT ACACAG.CTGTG AGG.CCT AG.CT ACAG.CTGT AAAC.GTTT AAAC.GTTT AAAG.CTTT AAAC.GTTT AC.GT AAAG.CTTT AAAC.GTTT AAC.GTT AG.CT AG.CT AATT.AATT AAAT.ATTT AC.GT AAAC.GTTT AAG.CTT AC.GT ACACAG.CTGTG AAAC.GTTT AAAC.GTTT AAC.GTT AAAT.ATTT AT.AT AAAC.GTTT AC.GT AAC.GTT AAAC.GTTT AC.GT AAAT.ATTT AAAC.GTTT AC.GT AAAG.CTTT AAT.ATT AG.CT AAAC.GTTT ACTC.GAGT AC.GT AAAG.CTTT AAAC.GTTT AAAAG.CTTTT AT.AT AAAC.GTTT AAAT.ATTT AATG.CATT AAC.GTT

3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3

70081463 70220104 70298457 70349329 70384560 70421368 70424037 71074117 71105412 71453836 71519704 71617772 71746418 71831003 71863802 71873861 72381108 72563191 72626791 72729683 73443640 74059213 74229873 74252027 74373332 74410699 74472764 74559439 74839718 74863532 74865462 75015716 75125050 75610001 75827776 75877167 75931799 76003804 76111213 76147209 76216374 76283156 76520931 76554021 76621069 76667819 76807945 77283586 77360425 77360425 77643127 77645466 77657161 77721672 77925315 77985710 77990885 78071010 78153407 78265147 78312629 78314264 78317993 78332195 78502611 78577938 78591128 78599544 78961986 79030432 79256888 79413749 79481548 79799653 79856508 79900740 80084228 80166867 80294181 80670789 80753419 81028486 81166763 81327236

70081476 70220120 70298475 70349348 70384571 70421397 70424064 71074130 71105423 71453872 71519715 71617783 71746436 71831029 71863818 71873886 72381120 72563200 72626810 72729693 73443663 74059229 74229887 74252037 74373345 74410713 74472779 74559449 74839732 74863554 74865482 75015740 75125061 75610019 75827799 75877176 75931819 76003818 76111223 76147222 76216388 76283180 76520943 76554047 76621080 76667836 76807963 77283605 77360436 77360436 77643142 77645488 77657171 77721693 77925327 77985719 77990910 78071036 78153429 78265164 78312652 78314280 78318006 78332205 78502625 78577956 78591137 78599562 78962005 79030442 79256906 79413781 79481558 79799667 79856530 79900750 80084239 80166887 80294204 80670804 80753441 81028504 81166781 81327249

4.66667 5.66667 4.75 6.66667 4 7.5 14 4.66667 3 18.5 6 3 4.75 6.75 5.66667 8.66667 6.5 5 6.66667 5.5 6 8.5 3.75 5.5 7 7.5 8 5.5 7.5 7.66667 5.25 5 6 4.75 8 5 3.5 5 5.5 3.5 3.75 6.25 3.25 6.75 6 4.5 4.75 6.66667 6 6 4 5.75 5.5 5.5 4.33333 5 4.33333 6.75 5.75 6 6 8.5 3.5 5.5 5 4.75 5 4.75 5 5.5 4.75 11 5.5 3.75 5.75 5.5 3 5.25 4.8 8 5.75 4.75 4.75 4.66667

. . . . . . . . ENSSSCT00000023158 . . ENSSSCT00000009049 ENSSSCT00000009054 ENSSSCT00000009054 ENSSSCT00000009065 ENSSSCT00000009066 ENSSSCT00000009091 . . . . . . . . . ENSSSCT00000009103 ENSSSCT00000009103 . . . . . . . . ENSSSCT00000009126 ENSSSCT00000009127 ENSSSCT00000009128 . . ENSSSCT00000009130 . . ENSSSCT00000009134 ENSSSCT00000009134 ENSSSCT00000009134 . ENSSSCT00000009140 ENSSSCT00000009141 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000024583 . . ENSSSCT00000030136

. . . . . . . . MRPL19 . . M1AP AUP1 AUP1 . LBX2 STAMBP . . . . . . . . . DYSF DYSF . . . . . . . . MXD1 . ANXA4 . . AAK1 . . ANTXR1 ANTXR1 ANTXR1 . APLF FBXO48 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic 3'utr intergenic intergenic intron intron intron promoter promoter intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intron intergenic intergenic intron intron intron intergenic intron promoter intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic promoter

-0.229 -0.075 -0.01 . -0.004 0.134 1.091 0.185 . -0.138 0.113 . 0.105 -0.11 0.045 -0.016 0.157 0.182 0.219 -0.073 . . . -0.058 0.075 . -0.136 -0.013 . 0.261 0.326 -0.123 . -0.168 0.122 -0.269 0.153 0.401 0.035 -0.01 . 0.081 0.16 . 0.06 -0.104 . 0.204 0.076 0.076 0.007 -0.037 0.035 . 0.359 -0.168 -0.051 0.594 0.404 . . . . 0.082 0.212 0.179 -0.285 -0.061 0.09 0.166 0.976 0.107 0.077 0.076 0.08 0.162 . 0.158 . . -0.012 0.193 -0.077 0.264

rs790375198 . rs789715611 rs791721503 654910 rs7926 rs790180251 rs789980403 rs791714990 . rs791406410 rs793518493 rs792467269 rs793045219 rs792896544 rs793003089 rs792518040 rs786939946 . . rs790803160 . . rs789400673 397414 rs7872 rs791470502 . . . rs786387139 rs788434435 rs792203158 . . rs786460534 rs790661251 . 052634 rs7900 . . rs790186859 rs788040403 . rs793814819 rs786741692 rs792927723 rs793525297 rs788577922 rs791130116 . . rs791932898 rs793579987 . rs793332583 rs787199631 . rs789181190 rs792073410 rs793156286 rs793625368 rs793110439 rs788975633 rs792600513 rs791711779 rs793062317 970829 rs7881 . rs792644842 rs789413936 479862 rs7935 . rs787650289 rs790861052 rs790792578 821105 rs7880 rs787108968 . rs788499942 rs786712624 rs791772707 rs787690095 rs787838005 918907 rs7863 rs788481606

2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 3 2 4 4 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 3 4 2 2 3 2 2 2 2 2 2 2 2 4 2 2 2 2 2 3 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 3 2 2 2 2

AT.AT AT.AT AAC.GTT ACAT.ATGT AG.CT AT.AT AG.CT AC.GT AAAAC.GTTTT AC.GT AAC.GTT AAC.GTT AAAT.ATTT AAAC.GTTT AG.CT AAG.CTT AC.GT AAAC.GTTT AG.CT AC.GT AC.GT AC.GT AG.CT AT.AT AAAT.ATTT AAAC.GTTT AC.GT AAATT.AATTT AAAT.ATTT AAAAC.GTTTT AC.GT AG.CT AT.AT ACAG.CTGT AAAAT.ATTTT AAAAC.GTTTT AAAAC.GTTTT AAAT.ATTT AT.AT AT.AT AAAG.CTTT AAAC.GTTT AAC.GTT AT.AT AGATAT.ATATCT AG.CT AT.AT AT.AT AAC.GTT AT.AT AT.AT AG.CT AAAC.GTTT AAAC.GTTT AAAT.ATTT AG.CT AC.GT AC.GT AAAT.ATTT AAAT.ATTT AT.AT AAAAC.GTTTT ACC.GGT AAT.ATT AAT.ATT AAC.GTT AAAAC.GTTTT AAT.ATT AT.AT ATC.GAT AAAAC.GTTTT AAT.ATT AATT.AATT AG.CT AC.GT AG.CT AT.AT AT.AT AC.GT AG.CT AAAT.ATTT AAAAC.GTTTT AAAAT.ATTTT AAAC.GTTT

3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3

81358479 81557990 81604966 81796755 82108068 82469516 82670980 82810840 82946284 83261922 83544642 83842812 84984734 84988643 85157237 85223587 85460461 85748055 85823034 86055984 86114397 86221712 86232296 86246305 86375061 86421253 86527505 86551620 86736142 86823342 86985821 87042989 87182468 87219965 87561285 87637724 88056120 88060017 88247084 88483069 88513104 88630083 88874567 88899445 88909158 88948328 88953185 88963436 89070809 89152486 89168887 89221570 89373092 89764134 89838763 89943980 90139903 90191165 90750562 90775286 90805609 90844289 90884328 91147213 91147213 91265987 91285285 91331105 91384670 91728654 91786566 91866725 92030613 92058356 92059526 92073844 92239168 92249093 92297569 92822863 92959695 92991737 92992482 93009106

81358488 81557999 81604979 81796773 82108079 82469525 82670990 82810870 82946304 83261934 83544658 83842825 84984752 84988661 85157249 85223610 85460483 85748090 85823061 86055998 86114411 86221727 86232310 86246323 86375078 86421279 86527515 86551638 86736164 86823366 86985835 87043002 87182477 87219991 87561304 87637748 88056134 88060039 88247094 88483083 88513126 88630099 88874580 88899456 88909186 88948338 88953194 88963445 89070824 89152507 89168898 89221589 89373119 89764147 89838785 89944000 90139923 90191199 90750582 90775300 90805621 90844325 90884347 91147230 91147230 91265999 91285303 91331123 91384679 91728671 91786583 91866738 92030631 92058367 92059538 92073858 92239178 92249116 92297595 92822873 92959721 92991757 92992499 93009117

5 5 4.66667 4.75 6 5 5.5 15.5 4.2 6.5 5.66667 4.66667 4.75 4.75 6.5 8 11.5 9 14 7.5 7.5 8 7.5 9.5 4.5 6.75 5.5 3.8 5.75 5 7.5 7 5 6.75 4 5 3 5.75 5.5 7.5 5.75 4.25 4.66667 6 4.83333 5.5 5 5 5.33333 11 6 10 7 3.5 5.75 10.5 10.5 17.5 5.25 3.75 6.5 7.4 6.66667 6 6 4.33333 3.8 6.33333 5 6 3.6 4.66667 4.75 6 6.5 7.5 5.5 12 13.5 5.5 6.75 4.2 3.6 3

. . ENSSSCT00000028590 . . . . . . . . . ENSSSCT00000009185 ENSSSCT00000009185 . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000009192 ENSSSCT00000009192 . . . . . . . . . . . . . . . ENSSSCT00000009193 ENSSSCT00000009193 . ENSSSCT00000009194 ENSSSCT00000009194 ENSSSCT00000009201 ENSSSCT00000026044 ENSSSCT00000009199 . . ENSSSCT00000009205 ENSSSCT00000032131 . . . . . . . . . . ENSSSCT00000023995 . . . . . . . .

. . . . . . . . . . . . REL REL . . . . . . . . . . . . . . . . . . . . . . VRK2 VRK2 . . . . . . . . . . . . . . . . . . EFEMP1 EFEMP1 MTIF2 RPS27A CLHC1 . . RTN4 EML6 . . . . . . . . . . GPR115 . . . . . . . .

intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intron intron intron intron intron intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

-0.178 . 0.302 0.289 . 0.523 2.262 . 0.152 . 0.176 . 0.065 0.019 . 0.526 0.161 -0.115 0.003 0.262 . 1.354 0.239 0.134 0.01 0.017 0.294 0.081 0.007 -0.058 . 0.899 1.301 -0.064 0.563 -0.26 . 0.196 0.187 . -0.079 0.092 0.1 . -0.173 . -0.095 0.119 . . 0.125 . 0.06 . -0.117 0.141 1.064 0.271 2.367 1.64 . -0.009 . 0.04 0.04 0.119 . 0.206 0.207 0.282 . . -0.154 -0.097 0.055 0.82 0.225 . . 0.232 . . . -0.048

rs791270067 rs790473996 rs792812239 556161 rs7895 . 822515 rs7871 rs792856320 rs788907618 327597 rs7875 . 907934 rs7931 rs789302385 rs790365270 rs788034905 rs787004227 rs793010251 . 586391 rs7901 rs790490510 rs787897799 581438 rs7865 . rs791281821 . 086902 rs7883 813163 rs7909 . rs793580083 rs793504276 rs787066139 . rs788704220 rs789684120 rs791322659 rs792612432 . rs786739719 rs786651940 rs788302290 rs790980392 rs787944015 rs788944176 rs788045280 883000 rs7862 853054 rs7905 rs790543712 178031 rs7882 rs792166769 rs791945823 . rs787272654 . rs786358257 rs788940478 872962 rs7905 . . rs789236620 rs790305446 rs793701981 rs789469141 rs786310564 rs789801513 rs789224129 rs789224129 rs787617788 rs789344168 . rs787288524 rs789650928 102647 rs7923 . 402176 rs7891 rs792041475 892783 rs7873 rs792207116 rs789633216 rs793461866 rs786646402 . rs790475272 rs792517012 rs789309032 rs788469028

2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 5 3 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 3 3 2 2 2 2 3 3 2 2 3 2 3 2 2 6 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2

AG.CT AAT.ATT AG.CT AC.GT AAT.ATT AC.GT AAATT.AATTT AT.AT AC.GT AAAT.ATTT AAAT.ATTT AAAC.GTTT AAC.GTT AAAAC.GTTTT AAAC.GTTT AAT.ATT AC.GT AATG.CATT ATC.GAT AAAAC.GTTTT AAAG.CTTT AC.GT AAAAC.GTTTT AC.GT AAAT.ATTT AAAC.GTTT AG.CT AAAC.GTTT AT.AT AT.AT AAAC.GTTT AT.AT AC.GT AAAC.GTTT AAC.GTT AC.GT AAAT.ATTT AAAG.CTTT AC.GT AAAG.CTTT AAC.GTT AAAC.GTTT AAAAAT.ATTTTT ACTG.CAGT AAAG.CTTT AG.CT AAAC.GTTT AAAC.GTTT AATG.CATT AT.AT AAAT.ATTT AAAAC.GTTTT AC.GT AAAAG.CTTTT AGC.GCT AAT.ATT AC.GT AATC.GATT AAAC.GTTT AAAT.ATTT AAAAG.CTTTT AT.AT AAC.GTT AAC.GTT AAAT.ATTT AAAAC.GTTTT AAACTC.GAGTTT AAAAC.GTTTT AAC.GTT ATC.GAT AATG.CATT AG.CT AACT.AGTT AAAC.GTTT AAAC.GTTT AT.AT AAAAT.ATTTT AAAC.GTTT AAAC.GTTT AC.GT AT.AT AC.GT AC.GT AAAC.GTTT

3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3

93038465 93169330 93301112 93382452 93741993 93796978 93821052 94168685 94254656 94499870 94738822 94821267 94850873 94885149 94908378 95051133 95062358 95870024 95935225 95949724 96056440 96061206 96236443 96382811 96707470 96873280 97202655 97227298 97284859 97380372 97392899 97477799 97539645 97595684 97608006 97616356 97918517 98033243 98141031 98473106 98509532 98788793 98802086 98825336 99290273 99422179 99486070 99738233 99869497 99984366 100029898 100076823 100189729 100363722 100481749 100691855 100775687 100901653 101066847 101200450 101736530 102209333 102249691 102249691 102289615 102337096 102386564 102480066 102552237 103076951 103406215 103493723 103511676 103869609 104245736 104294739 104472558 104568463 104866090 104908825 104941655 104990350 105087291 105193695

93038475 93169350 93301121 93382466 93742010 93796988 93821068 94168701 94254667 94499885 94738844 94821285 94850886 94885182 94908405 95051149 95062398 95870046 95935237 95949745 96056459 96061219 96236463 96382821 96707495 96873299 97202671 97227314 97284868 97380381 97392930 97477808 97539655 97595702 97608025 97616367 97918545 98033265 98141043 98473117 98509545 98788816 98802108 98825355 99290287 99422191 99486089 99738247 99869517 99984376 100029918 100076846 100189747 100363744 100481764 100691869 100775697 100901686 101066863 101200468 101736557 102209344 102249708 102249708 102289650 102337127 102386587 102480083 102552251 103076968 103406236 103493732 103511698 103869627 104245758 104294750 104472575 104568486 104866108 104908849 104941664 104990365 105087301 105193712

5.5 7 5 7.5 6 5.5 3.4 8.5 6 4 5.75 4.75 4.66667 6.8 7 5.66667 20.5 5.75 4.33333 4.4 5 7 4.2 5.5 6.5 5 8.5 4.25 5 5 8 5 5.5 4.75 6.66667 6 7.25 5.75 6.5 3 4.66667 6 3.83333 5 3.75 6.5 5 3.75 5.25 5.5 5.25 4.8 9.5 4.6 5.33333 5 5.5 8.5 4.25 4.75 5.6 6 6 6 9 6.4 4 3.6 5 6 5.5 5 5.75 4.75 5.75 6 3.6 6 4.75 12.5 5 8 5.5 4.5

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000024756 FSHR intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009224 PPP1R21 intron ENSSSCT00000025707 FOXN2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009229 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009240 RHOQ intron ENSSSCT00000009245 EPAS1 intron . . intergenic ENSSSCT00000009246 PRKCE intron . . intergenic . . intergenic . . intergenic ENSSSCT00000009247 SRBD1 intron ENSSSCT00000009247 SRBD1 intron . . intergenic . . intergenic ENSSSCT00000009249 . promoter ENSSSCT00000009250 PREPL promoter ENSSSCT00000009250 PREPL intron ENSSSCT00000009251 . intron . . intergenic . . intergenic . . intergenic ENSSSCT00000032410 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

. . -0.08 0.128 . . -0.092 -0.118 -0.031 0.04 . 0.094 0.012 -0.008 . -0.09 0.232 0.045 -0.047 0.061 -0.083 -0.047 . 0.148 . . -0.102 0.036 . -0.105 . -0.627 0.052 -0.108 0.201 -0.049 0.051 0.179 0.825 -0.024 0.149 . . 0.05 . 0 0.047 0.027 0.484 0.03 0.055 -0.065 0.335 0.302 0.245 0.056 0.119 0.06 0.188 0.25 . 0.175 0.233 0.233 . -0.109 0.099 0.483 0.135 0.53 0.049 0.166 -0.13 -0.032 0.102 . . 0.016 0.153 0.151 0.121 . . .

rs791461811 883556 rs7896 rs690243232 . . rs790502528 rs793434337 . . rs787542236 rs789390028 rs788624615 rs790005002 rs789599268 344109 rs7914 rs792533571 rs789248421 rs789835797 rs790287793 rs792066476 138697 rs7885 rs792926568 . rs709029079 589858 rs7932 428124 rs7881 rs789506942 rs703902661 rs792158256 rs787714148 . rs788961049 rs789055584 rs789684427 rs793335022 rs786243770 rs786685108 rs790053748 968251 rs7868 rs793586692 rs692834837 rs790207494 . . rs791910003 587720 rs7878 rs790468781 rs788387164 rs788166857 rs786669131 rs790949526 rs789807451 . . rs790495579 . . rs789667161 rs789899037 rs793445862 rs789132833 059880 rs7888 rs789002244 rs789002244 525016 rs7870 727639 rs7915 rs791568739 rs790396945 562562 rs7920 207850 rs7913 . rs788688462 517665 rs7934 rs790908674 rs789695645 . 864579 rs7909 rs789355509 703802 rs7895 rs793302767 . rs787511400 rs788886211 rs792704484

3 2 3 4 2 2 2 2 3 2 2 2 2 2 2 2 4 2 2 2 2 3 2 4 2 2 3 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 4 3 4 3 3

AAAT.ATTT AAGC.GCTT AAAT.ATTT AAAC.GTTT AC.GT AAAC.GTTT AAAC.GTTT AC.GT AC.GT AAAC.GTTT AAAAC.GTTTT AAAAT.ATTTT AAC.GTT AGAGC.GCTCT AC.GT AAAAC.GTTTT AG.CT AAAAC.GTTTT AAAG.CTTT AG.CT AAC.GTT AAC.GTT ATAT.ATAT AAGG.CCTT AAT.ATT AAAC.GTTT AC.GT AAAC.GTTT AAAAT.ATTTT AAAG.CTTT AT.AT AAAC.GTTT AAAAG.CTTTT AAAAT.ATTTT AAT.ATT AAC.GTT AAAC.GTTT AT.AT AT.AT AAC.GTT AAG.CTT AAC.GTT AG.CT AAAT.ATTT AAAC.GTTT AT.AT AAAAT.ATTTT AAAC.GTTT AT.AT AG.CT AAAAC.GTTTT AT.AT AG.CT AC.GT AAG.CTT AAG.CTT AC.GT AAAT.ATTT AAAG.CTTT AAAG.CTTT AAC.GTT AAAG.CTTT AAAAT.ATTTT ACAT.ATGT AG.CT AAT.ATT AATG.CATT AG.CT AG.CT AG.CT ACGC.GCGT AG.CT AAAC.GTTT AAGG.CCTT AAAAC.GTTTT AAC.GTT AG.CT AC.GT AAAAC.GTTTT AAAC.GTTT AC.GT ACG.CGT AC.GT AGG.CCT

3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3

105411821 105530213 105788919 105856964 105864313 105913340 105973682 105990104 105992555 106316384 106352575 106358785 106511575 106524840 106528156 106574091 106853830 107087927 107095516 107551491 107739193 107834360 107950288 108319107 108363079 108955258 109027289 109476738 109926962 110179747 110667331 110825093 110844568 111031908 111157469 111229064 111369369 111497197 111565594 111666144 111680705 111968292 111989953 112005531 112024264 112144351 112228843 112523914 112550058 112713735 112920243 113170222 113347669 113353630 113362239 113719495 113772474 113934562 113967693 114326392 114395179 114448985 114554112 114580897 114713275 114730996 114778622 114812835 114972396 114982019 115856605 116344049 116398272 116413659 116507623 116536276 116861255 117119513 117195368 117601371 117952380 118077532 118131660 118461440

105411853 105530245 105788936 105856982 105864322 105913366 105973702 105990121 105992590 106316406 106352597 106358806 106511589 106524859 106528165 106574119 106853839 107087947 107095534 107551500 107739205 107834382 107950321 108319137 108363092 108955282 109027298 109476756 109926979 110179766 110667344 110825107 110844585 111031922 111157480 111229077 111369382 111497234 111565607 111666160 111680729 111968304 111989967 112005553 112024282 112144361 112228865 112523928 112550074 112713750 112920270 113170231 113347681 113353643 113362255 113719511 113772489 113934588 113967706 114326409 114395192 114448997 114554128 114580915 114713288 114731007 114778645 114812851 114972410 114982030 115856620 116344058 116398292 116413692 116507663 116536289 116861269 117119525 117195390 117601399 117952401 118077545 118131669 118461458

8.25 8.25 4.5 4.75 5 6.75 5.25 9 18 5.75 4.6 4.4 5 4 5 5.8 5 4.2 4.75 5 4.33333 7.66667 8.5 7.75 4.66667 6.25 5 4.75 3.6 5 7 3.75 3.6 3 4 4.66667 3.5 19 7 5.66667 8.33333 4.33333 7.5 5.75 4.75 5.5 4.6 3.75 8.5 8 5.6 5 6.5 7 5.66667 5.66667 8 6.75 3.5 4.5 4.66667 3.25 3.4 4.75 7 4 6 8.5 7.5 6 4 5 5.25 8.5 8.2 4.66667 7.5 6.5 4.6 7.25 11 4.66667 5 6.33333

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009277 MAP4K3 promoter ENSSSCT00000009277 MAP4K3 intron ENSSSCT00000009283 . promoter . . intergenic ENSSSCT00000009287 . promoter . . intergenic . . intergenic . . intergenic ENSSSCT00000023650 . intron . . intergenic ENSSSCT00000009297 PRKD3 intron ENSSSCT00000009301 STRN intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009313 LTBP1 intron ENSSSCT00000009313 LTBP1 intron ENSSSCT00000009313 LTBP1 intron . . intergenic ENSSSCT00000023086 . intron ENSSSCT00000009315 . intron ENSSSCT00000009316 BIRC6 intron ENSSSCT00000009319 MEMO1 intron ENSSSCT00000009319 MEMO1 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009326 XDH promoter ENSSSCT00000009326 XDH intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000036644 ALK intron . . intergenic . . intergenic . . intergenic ENSSSCT00000033256 ALK intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000023126 BRE intron . . intergenic . . intergenic

-0.133 0 -0.077 -0.091 . . 0.107 0.028 -0.006 0.187 -0.088 0.043 . -0.326 . . 0.038 0.268 0.272 0.859 . . 0.161 . 0.029 0.002 0.262 0.263 0.075 0.126 0.132 0.231 . 0.476 0.103 0.07 -0.117 0.121 0.059 0.047 -0.006 0.393 0.021 0.027 -0.049 0.134 0.102 . 0.017 . 0.078 . -0.125 0.508 0.009 0.001 -0.01 0.138 2.917 0.778 0.275 0.211 . -0.07 0.095 -0.008 . -0.14 . 0.058 -0.026 0.007 -0.023 . -0.03 0.204 -0.017 -0.051 0.115 . -0.2 0.246 0.159 0.678

rs792489256 rs792574275 rs788244502 rs791319280 . rs787862840 rs789928947 728899 rs7936 . . rs786643072 rs791687705 . rs789906711 rs787039751 rs702072022 . rs788315107 rs788109267 rs790065722 rs792584983 071912 rs7898 . . . 688866 rs7918 rs791273970 795575 rs7923 rs787165808 663085 rs7929 rs703982573 807534 rs7877 rs792743928 rs793192195 rs792663277 rs789993675 rs792307199 270239 rs7876 rs789837748 244353 rs7934 rs792552942 rs790477926 rs786408214 . rs792593944 rs792180771 rs788206993 723510 rs7911 rs787589739 rs790549863 413289 rs7893 rs787135092 . rs789834603 833849 rs7875 rs787910259 rs790622178 rs790699632 rs789844429 rs790308698 rs791115920 rs793763879 rs786495265 299827 rs7905 rs789128218 rs789609981 rs788772922 rs790327382 . . 079753 rs7924 939087 rs7876 rs793508544 289254 rs7899 rs789943936 rs788274998 rs790144974 . rs793679517 rs788740619 rs792763065 rs789726253 . 171846 rs7885

2 2 3 2 2 2 2 3 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 3 2 3 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 5 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 3 2 2 2 2 2 3 2 2 4 2 2 2

AC.GT AATG.CATT AAAC.GTTT AAAC.GTTT AAC.GTT AC.GT AG.CT AC.GT AAAC.GTTT AT.AT AT.AT AAC.GTT AAC.GTT AG.CT AAAAC.GTTTT AC.GT AC.GT AG.CT AT.AT AAACC.GGTTT AG.CT ACAT.ATGT AAC.GTT AT.AT AAG.CTT ACAG.CTGT AAAC.GTTT AC.GT AAAT.ATTT AG.CT AC.GT AG.CT AAT.ATT AAT.ATT AT.AT AG.CT AC.GT AAC.GTT AAT.ATT AACCC.GGGTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AT.AT AT.AT AT.AT AC.GT AG.CT AAT.ATT AC.GT AC.GT AAC.GTT AAC.GTT AAAT.ATTT AC.GT AC.GT AAAC.GTTT AAAC.GTTT AG.CT AAAT.ATTT AAT.ATT AT.AT AC.GT AAAAC.GTTTT AT.AT AGAT.ATCT ATCC.GGAT AAAG.CTTT AAAC.GTTT AT.AT AAAAC.GTTTT AAAC.GTTT AT.AT AAAC.GTTT AC.GT AAAACC.GGTTTT AG.CT AT.AT AG.CT AAAC.GTTT AC.GT AAAAT.ATTTT AAAAC.GTTTT AAAAAC.GTTTTT

3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3

119188657 119472662 119508390 119524595 120083285 120133140 120165616 120261106 120837619 121038000 121134303 121387560 121533145 121785949 121872592 121901728 121965790 122031644 122047557 122318227 122438123 122699663 122751933 122873130 122926658 123121193 123300628 123757249 123758705 123778460 124019262 124076413 124127943 124189769 124245076 124370867 124648011 124761245 124876024 125263024 125332387 125447926 125447926 125462389 125462389 125656268 125744563 125812973 126107665 126278559 126278559 126281801 126281801 126436786 126560242 126588273 126751910 126784091 126785713 126861055 126944132 127052509 127080472 127186856 127190487 127226787 127226911 127232019 127310051 127715759 127740983 127817520 128211693 128268786 128319815 128439038 128472156 128561180 128633208 128961407 129007138 129037124 129208988 129292867

119188675 119472703 119508407 119524609 120083304 120133153 120165626 120261115 120837642 121038018 121134318 121387585 121533159 121785963 121872613 121901743 121965802 122031658 122047567 122318249 122438135 122699698 122751958 122873143 122926679 123121215 123300642 123757259 123758718 123778469 124019274 124076422 124127954 124189785 124245091 124370878 124648022 124761256 124876037 125263040 125332401 125447944 125447944 125462399 125462399 125656278 125744577 125812985 126107680 126278575 126278575 126281816 126281816 126436806 126560256 126588297 126751930 126784105 126785742 126861082 126944155 127052518 127080482 127186876 127190496 127226814 127226925 127232032 127310075 127715768 127741005 127817550 128211710 128268800 128319829 128439058 128472173 128561189 128633219 128961425 129007149 129037158 129209006 129292891

9.5 10.5 4.5 3.75 6.66667 7 5.5 5 6 9.5 8 8.66667 5 7.5 4.4 8 6.5 7.5 5.5 4.6 6.5 9 8.66667 7 7.33333 5.75 3.75 5.5 3.5 5 6.5 5 4 5.66667 8 6 6 4 4.66667 3.4 3.75 4.75 4.75 5.5 5.5 5.5 7.5 6.5 5.33333 8.5 8.5 5.33333 5.33333 5.25 7.5 12.5 5.25 3.75 15 7 8 5 5.5 4.2 5 7 3.75 3.5 6.25 5 4.6 7.75 9 3.75 7.5 3.5 9 5 6 4.75 6 7 3.8 4.16667

ENSSSCT00000009365 ENSSSCT00000009371 . . ENSSSCT00000009382 ENSSSCT00000009382 ENSSSCT00000009382 ENSSSCT00000009384 ENSSSCT00000031886 ENSSSCT00000009386 ENSSSCT00000009387 . . ENSSSCT00000009392 ENSSSCT00000009397 ENSSSCT00000009399 . ENSSSCT00000009401 . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000025009 ENSSSCT00000023215 ENSSSCT00000023215 ENSSSCT00000025009 . . . . ENSSSCT00000009415 ENSSSCT00000031965 ENSSSCT00000009415 ENSSSCT00000031965 . . . . . . . . . . . . . . . . . . . . ENSSSCT00000009425 . . ENSSSCT00000024717 . . . . . . ENSSSCT00000009428

DPYSL5 intron C2orf70 intron . intergenic . intergenic ASXL2 intron ASXL2 intron ASXL2 intron DTNB intron . intron DNAJC27 intron ADCY3 intron . intergenic . intergenic FAM228A intron . intron C2orf44 intron . intergenic . intron . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic C2orf43 intron C2orf43 intron C2orf43 intron C2orf43 intron . intergenic . intergenic . intergenic . intergenic WDR35 intron WDR35 intron WDR35 intron WDR35 intron . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic SMC6 intron . intergenic . intergenic RAD51AP2 intron . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic FAM49A intron

0.207 -0.097 0.051 -0.016 0.159 . 0.218 0.208 . 1.097 . 0.252 0.163 . 0.194 0.202 . -0.261 0.218 0.051 0.912 0.065 0.078 0.462 0.078 . 0.051 0.04 0.243 -0.17 . -0.192 0.064 . . -0.019 . 0.268 . . . . . 0.271 0.271 0.276 0.078 . -0.147 . . . . 0.061 . 1.714 0.043 -0.111 0.133 . -0.04 -0.087 -0.187 -0.264 0.122 -0.035 0.054 0.056 -0.047 . . . . 1.117 0.117 -0.106 0.141 . 0.375 -0.277 -0.055 0.229 0.044 -0.161

. 229262 rs7885 rs790518947 rs789521871 rs789547809 rs789944333 648950 rs7901 rs790822480 rs791129439 rs790616895 rs790773869 356908 rs7930 rs787658730 . . 256014 rs7873 . rs792053086 rs787552140 530633 rs7913 rs786541883 rs790388440 rs787861805 rs787084816 . 167893 rs7900 rs789029189 rs793642645 rs788357131 . rs789944526 345479 rs7937 . . . . rs791596732 rs792264894 rs786733326 rs787373171 . rs788632839 rs788632839 407566 rs7912 407566 rs7912 rs792382431 rs787649374 rs786508856 rs790888831 . . rs793101570 rs793101570 rs793381164 . . rs787295211 rs791047494 rs790664457 rs793139242 . . rs791624296 rs789191765 rs788043692 rs790031624 rs787365795 246655 rs7897 rs788953389 rs788954530 rs792538814 rs787100207 rs793669856 rs786957286 . . 055842 rs7886 rs789162099 rs787215421 rs792732448 rs709790272 rs792531755 rs789206430 267447 rs7885

4 3 2 2 2 2 2 6 2 3 4 2 2 2 2 4 4 4 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 5 2 2 2 2 3 3 3 3 2 2 2 2 2 2 2 4 2 3 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 3 2 2 2 2 2

AC.GT AC.GT ACTC.GAGT AAAT.ATTT AAAC.GTTT AATG.CATT AAAAT.ATTTT AAAATG.CATTTT AAAAAG.CTTTTT AATC.GATT AAT.ATT AT.AT AC.GT AT.AT AT.AT AAAC.GTTT AAAC.GTTT AG.CT AC.GT AAAC.GTTT AC.GT AAAAC.GTTTT AAC.GTT AT.AT AT.AT AC.GT AAG.CTT AC.GT AAAT.ATTT AG.CT AAAT.ATTT AG.CT ACC.GGT AAC.GTT AAAC.GTTT AG.CT AC.GT AC.GT AAAC.GTTT AAAAC.GTTTT AAAC.GTTT AAAAC.GTTTT AG.CT AC.GT AAT.ATT AAAC.GTTT AT.AT AC.GT AACT.AGTT AATG.CATT AC.GT AAT.ATT AAGG.CCTT AC.GT AAAT.ATTT AAAAT.ATTTT AAAAT.ATTTT AAAT.ATTT AC.GT AAAC.GTTT AAAC.GTTT AAAC.GTTT AG.CT AT.AT AC.GT AG.CT AG.CT AG.CT ACACC.GGTGT AT.AT AG.CT AG.CT AAAGC.GCTTT AC.GT AAT.ATT AC.GT AG.CT AC.GT AC.GT AAAAAC.GTTTTT AT.AT AAG.CTT AAT.ATT AC.GT

3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4

129372691 129430504 129619945 129948506 130026412 130067626 130122335 130627568 131204417 131333359 131337772 131351645 131464896 131763273 131822391 131838731 131975669 132236959 132279645 132333631 132336638 132441791 132457949 132524354 132730905 132738006 132835008 132845324 132865487 132893408 132904048 133509451 133544992 134252919 134607641 134637254 135499540 135676870 136064437 136719095 136766002 137761441 138158994 138541310 138760284 138957218 139002197 139129714 139302652 139628663 139716374 140069320 140135343 140338928 140365107 141048960 141116010 141226210 143735764 144162775 1119405 1791485 2381826 3035800 3433760 4275361 4275361 4529041 4588547 4685724 4709654 4803051 5018758 5061699 5255251 5336241 5379583 5486359 5490762 5503508 5511670 5648168 5886377 5905391

129372703 129430518 129619965 129948524 130026430 130067655 130122354 130627588 131204439 131333385 131337783 131351656 131464906 131763287 131822402 131838750 131975691 132236982 132279669 132333655 132336650 132441814 132457965 132524371 132730921 132738033 132835021 132845341 132865505 132893424 132904061 133509463 133545005 134252933 134607657 134637270 135499550 135676882 136064460 136719118 136766018 137761459 138159003 138541320 138760312 138957237 139002206 139129724 139302673 139628686 139716390 140069334 140135365 140338937 140365127 141048984 141116029 141226229 143735813 144162797 1119426 1791503 2381838 3035816 3433771 4275379 4275379 4529053 4588569 4685742 4709664 4803065 5018774 5061717 5255263 5336256 5379602 5486371 5490774 5503529 5511683 5648181 5886392 5905408

6.5 7.5 5.25 4.75 4.75 7.5 4 3.5 3.83333 6.75 4 6 5.5 7.5 6 5 5.75 12 12.5 6.25 6.5 4.8 5.66667 9 8.5 14 4.66667 9 4.75 8.5 3.5 6.5 4.66667 5 4.25 8.5 5.5 6.5 6 4.8 4.25 3.8 5 5.5 9.66667 5 5 5.5 5.5 6 8.5 5 5.75 5 5.25 5 4 5 25 5.75 5.5 4.75 6.5 8.5 6 9.5 9.5 6.5 4.6 9.5 5.5 7.5 3.4 9.5 4.33333 8 10 6.5 6.5 3.66667 7 4.66667 5.33333 9

. . . . . . . ENSSSCT00000009431 . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000009440 . ENSSSCT00000009447 . ENSSSCT00000026647 . . . . . . . . . . . . . . . . ENSSSCT00000009464 . . . . . . . ENSSSCT00000006516 . . ENSSSCT00000034533 ENSSSCT00000006522 . . . . . . . . . . . . . . . . .

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ROCK2 . NOL10 . MBOAT2 . . . . . . . . . . . . . . . . DCDC2C . . . . . . . AGO2 . . FAM135B FAM135B . . . . . . . . . . . . . . . . .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intron intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

-0.086 -0.142 -0.241 -0.087 0.087 -0.338 -0.29 0.437 . -0.01 . 0.212 . -0.025 -0.163 . -0.09 . . -0.123 0.13 -0.416 -0.195 0.06 . -0.058 -0.129 -0.001 . -0.145 -0.248 -0.169 -0.047 3.313 . 1.267 -0.098 0.082 -0.02 -0.105 -0.366 0.159 -0.37 . -0.172 . . . -0.098 -0.237 -0.471 -0.124 -0.223 -0.3 0.549 -0.304 0.168 -0.713 0.485 . . -0.135 . 0.007 . -0.216 -0.216 -0.282 -0.114 -0.282 -0.443 -0.256 -0.207 -0.223 -0.084 0.133 -0.208 -0.203 -0.062 -0.204 -0.014 -0.328 -0.147 -0.216

rs791214230 rs789337606 278398 rs7933 rs792856937 229117 rs7914 rs792027126 296634 rs7893 540320 rs7874 rs787371550 rs788599680 rs786322765 rs793272376 . rs788840906 rs789016264 rs792408509 865019 rs7924 . rs788854088 732352 rs7888 . rs789871868 480335 rs7924 rs789988741 rs786593200 rs788781721 . 151958 rs7926 . rs788400116 rs788879585 rs787663056 . rs793403816 rs790213134 rs787363649 . rs788289728 719610 rs7891 rs788816284 889492 rs7933 rs792594308 . 273264 rs6996 rs789077091 rs793001339 rs790582314 rs793241759 483905 rs7924 357544 rs7929 . 186471 rs7922 rs787667650 rs789614301 428727 rs7893 741787 rs7877 136465 rs7876 rs790150722 . 560756 rs7899 rs786444172 rs787535543 964148 rs7913 852362 rs7936 . rs702488221 rs702488221 rs789481578 646588 rs7901 rs787328281 rs786839524 rs787469393 . rs789256918 rs793032314 345528 rs7937 922220 rs7890 775467 rs7872 337345 rs7929 rs790701871 378333 rs7929 rs786969173 rs791844345 rs787707652

2 2 2 2 2 3 2 2 2 2 2 2 3 2 2 2 2 4 2 2 2 2 2 2 2 2 2 3 2 2 2 4 2 2 3 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 4 3 2 3 2 2 2 4 5 2 2 2 2 4 2 2 2 2 2 2 2 3 2 3 2 2 2 3 3 2 2 6 2 4

AC.GT AC.GT AAAAAT.ATTTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AC.GT AAAC.GTTT AC.GT AC.GT AC.GT AATG.CATT AGCCC.GGGCT AGATAT.ATATCT AG.CT AG.CT AAC.GTT AAAC.GTTT AAAC.GTTT AAAT.ATTT AAAT.ATTT AAC.GTT AAAC.GTTT ATCC.GGAT AC.GT AGG.CCT AAC.GTT AAAAC.GTTTT AATG.CATT AAAC.GTTT AAAAG.CTTTT AAAC.GTTT AGGG.CCCT AAAT.ATTT AAC.GTT ACAT.ATGT ACAT.ATGT AT.AT AG.CT AAC.GTT AG.CT AC.GT AAT.ATT AAAC.GTTT AAAT.ATTT ATC.GAT AT.AT AC.GT AAAAAT.ATTTTT AT.AT AG.CT AAAC.GTTT AC.GT AAAC.GTTT AAAC.GTTT AAGAG.CTCTT AAAAAC.GTTTTT AAAC.GTTT AAAT.ATTT AAAT.ATTT AC.GT AC.GT AT.AT AT.AT AAAAT.ATTTT AAAAT.ATTTT AAAAC.GTTTT AC.GT AAAC.GTTT AC.GT AGAT.ATCT AAAAT.ATTTT ACC.GGT AT.AT AATC.GATT AAAAC.GTTTT AC.GT AAC.GTT AT.AT AGGG.CCCT AC.GT AC.GT AGG.CCT AC.GT

4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4

5936063 6025135 6083094 6180033 6180033 6180033 6242958 6324318 6561317 6948626 7077369 7081076 7435013 7447065 7492546 7543767 7812501 8440418 8529005 8630675 8630675 8727804 8810103 8954675 8959633 8995151 9888015 10687472 10711512 10770069 11079013 11094146 11264438 11522729 11535903 11755897 11819320 12073352 12115242 12179984 12289638 12378700 12682848 12743437 12809545 12820506 12854629 13228469 13240829 13391073 13392147 13430292 13558562 13565672 13645065 14443727 14612991 14692772 14827673 15101766 15186550 15186550 15218845 15218845 15284545 15913328 15949757 16162979 16335622 16383655 16441962 16701839 16716370 16775843 16790277 16807317 16898815 17139111 17184361 17291439 17305911 17524880 17661863 17686018

5936081 6025145 6083113 6180051 6180051 6180051 6242967 6324335 6561326 6948635 7077379 7081099 7435027 7447095 7492556 7543784 7812514 8440435 8529029 8630693 8630693 8727820 8810122 8954696 8959652 8995169 9888036 10687492 10711528 10770087 11079031 11094170 11264450 11522750 11535918 11755916 11819334 12073364 12115251 12179996 12289647 12378709 12682866 12743451 12809567 12820520 12854646 13228480 13240851 13391090 13392158 13430315 13558576 13565699 13645084 14443743 14613015 14692803 14827689 15101786 15186560 15186560 15218877 15218877 15284564 15913357 15949784 16163000 16335635 16383666 16441982 16701863 16716383 16775868 16790298 16807336 16898827 17139127 17184370 17291450 17305925 17524894 17661875 17686046

9.5 5.5 3.33333 4.75 4.75 4.75 5 4.5 5 5 5.5 6 3 5.16667 5.5 9 4.66667 4.5 6.25 4.75 4.75 5.66667 5 5.5 10 6.33333 7.33333 4.2 4.25 4.75 3.8 6.25 3.25 5.5 5.33333 5 3.75 6.5 5 4.33333 5 5 6.33333 3.75 5.75 5 9 6 3.83333 9 6 6 7.5 7 5 3.4 4.16667 8 4.25 5.25 5.5 5.5 16.5 16.5 4 6 5.6 11 3.5 6 5.25 5 4.66667 13 5.5 4 6.5 5.66667 5 3 7.5 7.5 4.33333 14.5

. . intergenic . . intergenic . . intergenic ENSSSCT00000006524CU151851.1 intron ENSSSCT00000036563CU151851.1 intron ENSSSCT00000035168CU151851.1 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000033897CU571095.1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000006533 PHF20L1 intron ENSSSCT00000006534 . intron ENSSSCT00000034663 LRRC6 intron ENSSSCT00000006535 LRRC6 intron . . intergenic . . intergenic ENSSSCT00000029622 . promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000006545 GSDMC promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000006552 KIAA0196 intron ENSSSCT00000026728 . promoter ENSSSCT00000034190 KIAA0196 intron ENSSSCT00000006552 KIAA0196 intron . . intergenic ENSSSCT00000006560 TMEM65 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000027516 FAM91A1 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000006566 ATAD2 intron ENSSSCT00000006566 ATAD2 intron ENSSSCT00000006566 ATAD2 intron ENSSSCT00000024326 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

-0.633 -0.192 0.303 . . . -0.105 0.05 0.012 . 0.078 0.154 -0.137 -0.391 -0.144 0.055 -0.124 -0.044 0.028 -0.282 -0.282 -0.194 -0.183 -0.108 -0.118 -0.267 -0.063 -0.115 -0.264 . -0.188 . 0.023 0.021 0.172 -0.255 -0.327 0.037 -0.151 -0.117 -0.134 -0.086 -0.226 . -0.175 -0.28 -0.155 0.133 0.053 -0.19 1.215 -0.11 -0.037 . 0.203 0.495 0.444 -0.145 -0.203 0.11 0.095 0.095 -0.207 -0.207 0.174 . -0.059 0.125 -0.18 1.081 0.004 . -0.038 0.264 . . . . . -0.289 -0.09 0.125 0.039 0.207

rs790595934 rs789333401 rs787268321 rs793747849 rs793747849 rs793747849 . rs792477147 rs788433497 . . 436563 rs7914 . rs793622545 054383 rs7903 . rs789986688 rs789081001 409911 rs7892 rs793661939 rs793661939 . rs793300960 rs789261847 rs786231170 rs793454411 rs793869607 . rs787575676 044205 rs7887 rs793054851 437492 rs7869 rs790569505 rs788927901 rs790709093 rs787109231 997543 rs7930 rs789883185 . rs789006013 809071 rs7881 . rs788653145 rs786543882 rs792108620 rs790089840 468418 rs7933 479763 rs7905 rs792057455 rs787165400 . rs792824417 rs787019350 095279 rs7901 rs789778945 rs792049048 733021 rs7889 967910 rs7882 rs793855200 rs788516833 . . 755984 rs7895 755984 rs7895 rs786493486 rs790671232 rs790348430 rs709860514 rs788673593 rs789870026 rs787170842 670217 rs7884 rs790856571 rs792103838 rs793876993 829758 rs7909 rs694051292 rs790332987 . . rs791887360 rs699721282 rs792035373 .

3 2 2 2 2 2 2 2 2 2 4 2 2 2 3 2 2 2 2 2 2 2 2 2 3 3 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 4 2 3 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 4 4 2 2 3 2 2 2 2 2 2 2

AAAC.GTTT AG.CT AG.CT AAAC.GTTT AG.CT AAT.ATT AAAT.ATTT AC.GT AGC.GCT AAG.CTT AG.CT AC.GT AAAC.GTTT AAAAC.GTTTT AAAC.GTTT AC.GT AAAAT.ATTTT AAAAT.ATTTT AAAC.GTTT AAAC.GTTT AAAACC.GGTTTT AAAACC.GGTTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AT.AT AT.AT AT.AT AT.AT AAACC.GGTTT AAACC.GGTTT AAACC.GGTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AT.AT AT.AT AT.AT AAT.ATT AAT.ATT AAT.ATT AAATC.GATTT AAAC.GTTT AAT.ATT AATG.CATT AAT.ATT AAAAG.CTTTT AG.CT AC.GT AT.AT AAGG.CCTT AT.AT AC.GT AG.CT AC.GT AAAT.ATTT AATG.CATT AG.CT AAAAAC.GTTTTT AAAG.CTTT AG.CT AAAAC.GTTTT AC.GT AC.GT AC.GT AC.GT AAAT.ATTT AG.CT AC.GT AC.GT AC.GT AT.AT AT.AT AAT.ATT AG.CT AG.CT AAAAC.GTTTT AC.GT ACTG.CAGT AAAT.ATTT AAAC.GTTT AC.GT AC.GT

4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4

17935971 17994958 18137054 18236573 18261618 18534144 18546564 18749306 18803246 18807366 19011423 19016979 19225948 19250745 19253068 19374834 19774229 19774229 19806287 19806287 19810122 19810122 19841774 19841774 20006695 20006695 20056152 20056152 20056152 20056152 20088258 20088258 20088258 20103532 20103532 20103532 20264682 20264682 20264682 20275152 20275152 20275152 20378715 20410270 20448994 20504033 20504839 20572605 20615447 20648955 20655478 20674671 20839501 20997483 21200378 21247674 21402576 21466125 21710514 21738843 21859604 21864582 21872410 21963529 22088178 22088178 22281117 22313313 22318563 22523383 22606937 22610185 22703190 22748154 22766210 22820289 22820289 22852602 22856504 22870012 22873035 22946754 23065350 23065350

17935988 17994989 18137069 18236598 18261632 18534158 18546586 18749327 18803258 18807390 19011436 19016990 19225966 19250770 19253088 19374852 19774253 19774253 19806309 19806309 19810142 19810142 19841802 19841802 20006718 20006718 20056162 20056162 20056162 20056162 20088276 20088276 20088276 20103558 20103558 20103558 20264694 20264694 20264694 20275164 20275164 20275164 20378742 20410292 20449017 20504059 20504850 20572628 20615461 20648965 20655490 20674688 20839513 20997495 21200390 21247686 21402595 21466143 21710524 21738864 21859623 21864604 21872433 21963556 22088195 22088195 22281131 22313330 22318574 22523398 22606957 22610199 22703199 22748165 22766228 22820300 22820300 22852626 22856542 22870034 22873067 22946776 23065366 23065366

4.5 16 8 6.5 7.5 5 5.75 11 4.33333 8.33333 7 6 4.75 5.2 5.25 9.5 5 5 5.75 5.75 3.5 3.5 7.25 7.25 6 6 5.5 5.5 5.5 5.5 3.8 3.8 3.8 6.75 6.75 6.75 6.5 6.5 6.5 4.33333 4.33333 4.33333 5.6 5.75 8 6.75 4 4.8 7.5 5.5 6.5 4.5 6.5 6.5 6.5 6.5 5 4.75 5.5 3.66667 5 11.5 4.8 14 9 9 7.5 4.5 6 8 10.5 7.5 5 6 6.33333 6 6 5 19.5 5.75 8.25 5.75 8.5 8.5

. . . . . . . . . . . . . . . . ENSSSCT00000035287 ENSSSCT00000006580 ENSSSCT00000035287 ENSSSCT00000006580 ENSSSCT00000035287 ENSSSCT00000006580 ENSSSCT00000035287 ENSSSCT00000006580 ENSSSCT00000036252 ENSSSCT00000034055 ENSSSCT00000034055 ENSSSCT00000036252 ENSSSCT00000006581 ENSSSCT00000034473 ENSSSCT00000006581 ENSSSCT00000034473 ENSSSCT00000036252 ENSSSCT00000006581 ENSSSCT00000034473 ENSSSCT00000036252 ENSSSCT00000006583 ENSSSCT00000033583 ENSSSCT00000034647 ENSSSCT00000006583 ENSSSCT00000033583 ENSSSCT00000034647 ENSSSCT00000006585 ENSSSCT00000006585 ENSSSCT00000006585 . . . ENSSSCT00000006587 . . . . . . . . . . . . . . . ENSSSCT00000006593 ENSSSCT00000033159 . . . . . . . . . ENSSSCT00000035755 ENSSSCT00000006597 . . . . . ENSSSCT00000033947 ENSSSCT00000006600

. . . . . . . . . . . . . . . . COL14A1 COL14A1 COL14A1 COL14A1 COL14A1 COL14A1 COL14A1 COL14A1 DEPTOR DEPTOR DEPTOR DEPTOR DEPTOR DEPTOR DEPTOR DEPTOR DEPTOR DEPTOR DEPTOR DEPTOR TAF2 TAF2 TAF2 TAF2 TAF2 TAF2 ENPP2 ENPP2 ENPP2 . . . MAL2 . . . . . . . . . . . . . . . EXT1 EXT1 . . . . . . . . . SLC30A8 SLC30A8 . . . . . RAD21 RAD21

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intron intron 3'utr intron intron intron intron intron intron intron intron intron intron intron intron intron intron intron intron intron intron intron intron intergenic intergenic intergenic 3'utr intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic promoter promoter intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intron intron

. -0.215 -0.022 . 0.226 0.379 0.049 0.134 -0.173 -0.271 0.163 1.06 . . -0.204 0.003 0.497 0.497 -0.172 -0.172 1.717 1.717 -0.405 -0.405 0.218 0.218 . . . . . . . 0.364 0.364 0.364 0.25 0.25 0.25 0.081 0.081 0.081 -0.369 0.46 -0.169 0.08 -0.073 0.05 0.395 0.131 0.092 0.003 -0.004 0.166 -0.05 0.055 -0.161 -0.095 0.066 0.134 0.363 -0.048 0.001 -0.047 1.316 1.316 . . 0.477 . 0.017 -0.036 -0.099 0.202 0.226 . . 0.334 0.041 0.164 0.097 0.104 . .

459050 rs7014 . rs786517363 . . rs789145513 381433 rs7911 rs788789661 rs788925205 rs787367049 . rs790883351 . 172182 rs7904 823127 rs7863 rs712100598 rs788098968 rs788098968 rs788355159 rs788355159 rs793260201 rs793260201 rs787937706 rs787937706 826352 rs7912 826352 rs7912 rs788345458 rs788345458 rs788345458 rs788345458 rs789452135 rs789452135 rs789452135 rs788621269 rs788621269 rs788621269 rs793721047 rs793721047 rs793721047 . . . rs793610594 rs788456489 rs792595269 158900 rs7905 . rs791852858 . . . rs792477340 rs788243844 rs792884111 745662 rs7934 459871 rs7883 rs787517754 rs789626174 508321 rs7923 rs791973844 722409 rs7925 rs793763025 rs790036415 . . . . 705535 rs7899 rs788091019 rs789076435 . rs790665028 . . . rs787479890 rs787479890 rs791498400 rs786562340 rs792377824 838782 rs7906 rs789538894 . .

4 4 2 2 3 2 2 4 2 2 3 2 2 2 2 3 2 2 2 2 2 2 3 3 2 2 3 3 3 3 2 2 2 2 2 2 4 4 4 2 2 2 2 3 2 2 2 2 2 2 3 2 2 2 2 2 3 2 2 2 2 2 3 3 3 3 2 2 2 2 4 2 2 3 2 2 2 2 6 2 2 2 3 3

AAAC.GTTT ACC.GGT AAC.GTT AAAC.GTTT AC.GT AC.GT AAAT.ATTT AG.CT AC.GT ATC.GAT AG.CT ACAT.ATGT AT.AT AC.GT AT.AT AT.AT AT.AT AAAT.ATTT AAAC.GTTT AAAAAC.GTTTTT AAC.GTT AAC.GTT AAAAT.ATTTT AC.GT AT.AT AC.GT AAAG.CTTT AG.CT AAAAC.GTTTT AAAC.GTTT AT.AT AAGT.ACTT AAAC.GTTT AT.AT AG.CT AAAC.GTTT AAC.GTT AC.GT AAAAC.GTTTT AT.AT AAT.ATT AAC.GTT AT.AT AAAAC.GTTTT AC.GT AAAC.GTTT AG.CT AAT.ATT AATG.CATT AT.AT AC.GT AC.GT ACAT.ATGT AG.CT AAT.ATT AC.GT AAAT.ATTT AC.GT AAC.GTT AG.CT AAC.GTT ACC.GGT AAT.ATT AC.GT AC.GT AAG.CTT AATC.GATT AC.GT AC.GT AAAG.CTTT AT.AT AAAAT.ATTTT AAAC.GTTT AAAAC.GTTTT AAAC.GTTT AAC.GTT AAT.ATT AC.GT AATG.CATT AAAG.CTTT AAAAC.GTTTT AC.GT AAT.ATT AAGG.CCTT

4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4

23125085 23152311 24552019 24554660 24699536 24839841 25094093 25190850 25219346 25309991 25317202 25329967 25472143 25488800 25504607 25653752 25695870 25848227 25951308 26057482 26188658 26194571 26259760 26408372 26566340 26956784 27337361 27403055 27733803 27745616 27787573 27810039 27893021 27912038 28107775 28630313 28767896 28829391 28906858 29006083 29133145 29290618 29549568 29870449 29879616 30252710 30264673 30865290 30970248 31018344 31063946 31063946 31605088 31614200 31784048 31949510 32142191 32409386 32839314 32851481 33051326 33377944 33592029 33668035 33781359 33815537 34082211 34280725 34331267 34331899 34333559 34347204 34549740 34788970 34805281 34950034 35066287 35083134 35252883 35365775 35538023 35810110 35881150 35881700

23125099 23152329 24552036 24554680 24699550 24839851 25094111 25190859 25219358 25310004 25317225 25329990 25472156 25488812 25504622 25653764 25695881 25848247 25951326 26057499 26188680 26194587 26259783 26408390 26566349 26956805 27337372 27403087 27733826 27745633 27787585 27810050 27893039 27912047 28107793 28630333 28767912 28829404 28906886 29006092 29133160 29290636 29549579 29870467 29879629 30252724 30264686 30865303 30970274 31018354 31063961 31063961 31605110 31614215 31784063 31949520 32142209 32409396 32839327 32851490 33051339 33377963 33592049 33668048 33781373 33815552 34082228 34280752 34331282 34331912 34333568 34347234 34549754 34788998 34805313 34950061 35066311 35083146 35252908 35365796 35538041 35810126 35881178 35881712

3.75 6.33333 6 5.25 7.5 5.5 4.75 5 6.5 4.66667 12 6 7 6.5 8 6.5 6 5.25 4.75 3 7.66667 5.66667 4.8 9.5 5 11 3 16.5 4.8 4.5 6.5 3 4.75 5 9.5 5.25 5.66667 7 5.8 5 5.33333 6.33333 6 3.8 7 3.75 7 4.66667 6.75 5.5 8 8 5.75 8 5.33333 5.5 4.75 5.5 4.66667 5 4.66667 6.66667 7 7 7.5 5.33333 4.5 14 8 3.5 5 6.2 3.75 5.8 8.25 9.33333 8.33333 6.5 6.5 5.5 3.8 8.5 9.66667 3.25

ENSSSCT00000006600 RAD21 intron ENSSSCT00000006600 RAD21 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000006604 TRPS1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000032782 CSMD3 intron ENSSSCT00000032782 CSMD3 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000006611 EBAG9 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000034120 TMEM74 5'utr ENSSSCT00000006620 TMEM74 promoter . . intergenic . . intergenic . . intergenic ENSSSCT00000006623 RSPO2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000006626 . 3'utr . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000006627 ZFPM2 intron ENSSSCT00000006627 ZFPM2 intron ENSSSCT00000006627 ZFPM2 intron ENSSSCT00000006627 ZFPM2 intron ENSSSCT00000006627 ZFPM2 intron ENSSSCT00000006627 ZFPM2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000006629 DPYS intron ENSSSCT00000006634 RIMS2 intron ENSSSCT00000006634 RIMS2 intron ENSSSCT00000006634 RIMS2 intron

. . 0.37 0.206 . . 0.162 0.013 -0.124 -0.115 0.059 -0.098 -0.058 -0.019 . . -0.084 -0.007 -0.021 -0.05 -0.123 . . 0.115 0.077 -0.103 -0.11 -0.02 -0.017 -0.014 -0.162 0.301 -0.057 . 0.089 -0.033 . . . 0.073 0.128 . 0.001 0.245 0.006 0.195 0.084 0.108 . 0.02 0.125 0.125 . . . . 0.03 . . 0.02 . 0.808 -0.037 -0.006 0.013 -0.176 . 0.443 0.222 0.046 -0.066 0.044 -0.211 . 0.086 . 0.042 0.397 . 0.022 . 0.117 0.149 0.238

723748 rs7935 rs788041336 rs791493224 rs790027003 rs793033031 rs790021406 . rs787062006 rs791987235 770108 rs7916 rs793126807 rs787376958 927175 rs7872 rs790900331 145723 rs7865 . . rs793596109 975130 rs7895 rs701864834 500313 rs7935 042062 rs7932 429424 rs7937 rs790945249 rs793740238 rs789666580 . rs792639487 956707 rs7886 rs790263585 rs788531378 rs792125711 rs789434998 . rs786787905 rs791608721 . rs793159059 rs791989803 rs791149212 581093 rs7900 496457 rs7893 rs791375101 . 757265 rs7877 rs792582363 rs788079395 rs790561795 rs791887749 966836 rs7886 603387 rs7879 603387 rs7879 rs702204322 . . rs787653506 rs790625674 . rs789863448 rs793868839 . rs793392309 rs787704827 . 990097 rs7898 877920 rs7906 rs786401776 rs792311825 . 593505 rs7891 rs787578503 rs703940018 rs791996694 rs786743055 rs786827137 rs792192542 rs791626818 794530 rs7892 075464 rs7868 112542 rs7937 rs704086484 143803 rs7884 rs696825635 .

2 2 4 2 2 2 2 2 2 3 4 2 4 2 3 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 4 2 2 2 2 4 2 2 2 2 2 2 3 2 2 2 2 2 2 2 4 2 2 3 2 2 3 3 2 2 5 4 2 2 2 2 3 2 2 2 2 2 2 2 3 2 2

AAT.ATT AAGC.GCTT AAC.GTT AAAAC.GTTTT AAAC.GTTT AAAAT.ATTTT AG.CT AC.GT AC.GT AAAC.GTTT AAAC.GTTT AAAT.ATTT AAAG.CTTT AT.AT AAAT.ATTT AATT.AATT AG.CT AG.CT AG.CT AAAAAC.GTTTTT AAAAAC.GTTTTT AAAAAC.GTTTTT AAAAAC.GTTTTT AAAAAC.GTTTTT AAAAAC.GTTTTT AAAAAC.GTTTTT AAAAAC.GTTTTT AAAAAC.GTTTTT AAAAAC.GTTTTT AAAAAC.GTTTTT AAAAAC.GTTTTT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AAAAC.GTTTT AATG.CATT AG.CT AAC.GTT AC.GT AAAC.GTTT AG.CT AAT.ATT AAAG.CTTT AAAT.ATTT AC.GT AAAC.GTTT AAAG.CTTT AAAT.ATTT AC.GT AG.CT AC.GT AC.GT AAAT.ATTT AATC.GATT AAAC.GTTT AG.CT AATG.CATT AT.AT AT.AT AAC.GTT AC.GT AAAC.GTTT AAAT.ATTT AC.GT AAC.GTT AG.CT AG.CT AAAC.GTTT AAAAC.GTTTT AAAC.GTTT AAAT.ATTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT

4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4

35909079 35962821 36072094 36262406 36331238 36468495 36815871 36820743 36918468 37033825 37264898 37296981 37306353 37675813 37781813 37855832 37858170 38010569 38010569 38174692 38174692 38174692 38174692 38174692 38174692 38174692 38174692 38174692 38174692 38174692 38174692 38180136 38180136 38180136 38180136 38180136 38180136 38180136 38180136 38180136 38180136 38180136 38180136 38320049 38329519 38444191 38575770 38629307 38979237 39054102 39274211 39285799 39369168 39377793 39384005 39469678 39595733 39619636 39821996 39936508 39956215 39965055 39979661 39982387 40008999 40118990 40258821 40322151 40496113 40584808 41010776 41142871 41325220 41327724 41455476 41466719 41522955 41628113 41633206 41643853 41726628 41726628 41809188 41809188

35909097 35962842 36072109 36262430 36331256 36468509 36815880 36820758 36918477 37033843 37264917 37297001 37306365 37675827 37781831 37855856 37858179 38010582 38010582 38174714 38174714 38174714 38174714 38174714 38174714 38174714 38174714 38174714 38174714 38174714 38174714 38180161 38180161 38180161 38180161 38180161 38180161 38180161 38180161 38180161 38180161 38180161 38180161 38320069 38329535 38444202 38575788 38629336 38979253 39054111 39274228 39285813 39369193 39377809 39384026 39469696 39595755 39619647 39822010 39936520 39956228 39965072 39979676 39982411 40009011 40119029 40258832 40322166 40496127 40584818 41010791 41142888 41325229 41327737 41455490 41466732 41522971 41628132 41633229 41643869 41726646 41726646 41809202 41809202

6.33333 5.5 5.33333 5 4.75 3 5 8 5 4.75 5 5.25 3.25 7.5 4.75 6.25 5 7 7 3.83333 3.83333 3.83333 3.83333 3.83333 3.83333 3.83333 3.83333 3.83333 3.83333 3.83333 3.83333 8.66667 8.66667 8.66667 8.66667 8.66667 8.66667 8.66667 8.66667 8.66667 8.66667 8.66667 8.66667 4.2 4.25 6 6.33333 15 4.25 5 6 3.75 6.5 8.5 5.5 4.75 5.75 6 7.5 6.5 7 4.5 4 6.25 6.5 10 6 8 5 5.5 4 4.5 5 4.66667 7.5 7 4.25 4 6 4.25 4.75 4.75 3.75 3.75

ENSSSCT00000006634 RIMS2 intron . . intergenic ENSSSCT00000029168 . intron . . intergenic . . intergenic ENSSSCT00000006637 DCAF13 intron . . intergenic . . intergenic ENSSSCT00000006643 ATP6V1C1 promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000035758CU633679.1 intron . . intergenic . . intergenic ENSSSCT00000035357 NCALD intron ENSSSCT00000006648 NCALD intron ENSSSCT00000036111 NCALD intron ENSSSCT00000035298 NCALD intron ENSSSCT00000035679 NCALD intron ENSSSCT00000006648 NCALD intron ENSSSCT00000032895 NCALD intron ENSSSCT00000035469 NCALD intron ENSSSCT00000033437 NCALD intron ENSSSCT00000035357 NCALD intron ENSSSCT00000033719 NCALD intron ENSSSCT00000034691 NCALD intron ENSSSCT00000033597 NCALD intron ENSSSCT00000034309 NCALD intron ENSSSCT00000036111 NCALD intron ENSSSCT00000035298 NCALD intron ENSSSCT00000035679 NCALD intron ENSSSCT00000006648 NCALD intron ENSSSCT00000032895 NCALD intron ENSSSCT00000035469 NCALD intron ENSSSCT00000033437 NCALD intron ENSSSCT00000035357 NCALD intron ENSSSCT00000033719 NCALD intron ENSSSCT00000034691 NCALD intron ENSSSCT00000033597 NCALD intron ENSSSCT00000034309 NCALD intron ENSSSCT00000006649 GRHL2 intron ENSSSCT00000006649 GRHL2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000006653 SNX31 intron ENSSSCT00000006653 SNX31 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000006656 RNF19A intron ENSSSCT00000006656 RNF19A intron . . intergenic ENSSSCT00000006660 RGS22 intron ENSSSCT00000006660 RGS22 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000006662 . intron ENSSSCT00000006662 . intron . . intergenic . . intergenic ENSSSCT00000030508 . intron ENSSSCT00000030508 . intron . . intergenic ENSSSCT00000006665 STK3 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000026541 . intron ENSSSCT00000026541 . 3'utr . . intergenic ENSSSCT00000023470 . intron ENSSSCT00000006669 . intron ENSSSCT00000006670 HRSP12 intron ENSSSCT00000023470 . promoter

0.121 . 0.118 0.173 . -0.022 0.092 0.083 0.159 0.345 -0.035 0.003 -0.096 0.111 . . -0.074 -0.073 -0.073 0.06 0.06 0.06 0.06 0.06 0.06 0.06 0.06 0.06 0.06 0.06 0.06 -0.127 -0.127 -0.127 -0.127 -0.127 -0.127 -0.127 -0.127 -0.127 -0.127 -0.127 -0.127 -0.119 -0.031 -0.02 . -0.002 -0.047 -0.148 0.128 . -0.187 0.092 0.186 0.032 0.139 0.275 0.458 0.098 . . 0.029 0.166 0.143 0.648 0.109 0.135 0.529 0.159 -0.083 0.293 . . -0.09 . -0.103 -0.019 . . . . 0.103 0.103

rs793302596 138804 rs7890 270986 rs7912 rs696189827 rs788656338 rs788380830 rs793084015 rs789966357 . rs793454367 820848 rs7866 rs791217992 rs791887842 rs786883455 rs789729881 rs790345029 rs787131631 rs791157844 rs791157844 rs789261322 rs789261322 rs789261322 rs789261322 rs789261322 rs789261322 rs789261322 rs789261322 rs789261322 rs789261322 rs789261322 rs789261322 rs793273220 rs793273220 rs793273220 rs793273220 rs793273220 rs793273220 rs793273220 rs793273220 rs793273220 rs793273220 rs793273220 rs793273220 rs787589205 . rs791153296 rs793800938 . rs787312116 rs789371624 rs792926022 rs792128919 rs791457235 rs793590163 rs791631132 rs787276169 284808 rs7908 rs787441047 . rs789508917 rs787811735 . . rs786476603 rs790538723 rs793602475 . rs786704459 rs793111008 . rs788734925 rs787112513 rs790943933 326084 rs7895 rs790150311 rs789916180 194394 rs7885 306904 rs7888 rs790229163 rs787208026 513669 rs7931 513669 rs7931 . .

2 2 2 2 2 2 2 2 3 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 4 3 2 2 2 2 2 2 2 2 2 3 2 2 2 2 4 2 2 2 2 2 2 4 4 2 2

AAAC.GTTT AAT.ATT AAAC.GTTT AAAAC.GTTTT AAAC.GTTT AG.CT AG.CT AAAG.CTTT AAAC.GTTT AAT.ATT AAAC.GTTT AT.AT AAC.GTT AAT.ATT AAAC.GTTT AT.AT AAAG.CTTT AC.GT AAAG.CTTT AAAAT.ATTTT AAAT.ATTT AC.GT AT.AT AAAGAT.ATCTTT AATG.CATT AAAAAC.GTTTTT AC.GT AC.GT AC.GT AAAC.GTTT AAT.ATT AT.AT AG.CT AAT.ATT AAAT.ATTT ACAG.CTGT AC.GT AG.CT AT.AT AG.CT AAAT.ATTT AAAC.GTTT AG.CT AAAAT.ATTTT AG.CT AG.CT AC.GT AT.AT AAAT.ATTT ACT.AGT AT.AT AT.AT AC.GT AAAAC.GTTTT AAC.GTT AT.AT AAAAC.GTTTT AG.CT AT.AT AT.AT AG.CT AC.GT AG.CT AAAT.ATTT AAAC.GTTT AAAG.CTTT AG.CT AT.AT AG.CT AAT.ATT AT.AT AAT.ATT AG.CT AT.AT AT.AT AC.GT AC.GT AAAT.ATTT AAAT.ATTT AAC.GTT AAAAC.GTTTT AC.GT AAAAC.GTTTT AAC.GTT

4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4

41809188 41947039 42024168 42263507 42473814 42522157 42883848 42917013 43125816 43174356 43234734 43306366 43511356 43578069 43591461 43817335 43882653 43979497 44015542 44038683 44242924 44271790 44272326 44336116 44532519 44870081 44877958 45127601 45176720 45189732 46034038 46074249 46232453 46331794 46362347 46505875 46750298 46939282 47104399 47105855 47344755 47383108 47433666 47460641 47964247 48138205 48144578 48166242 48170292 48552964 48707115 48743372 49257055 49559309 50026945 50316884 50401989 50416666 50949094 50956826 51130755 51133369 51631785 51677915 51704605 51853617 51948338 52094379 52205038 52210481 52220898 52496082 52612166 53401945 53712535 53738246 53749049 53969231 53973927 54044706 54114918 54149246 54268685 54426683

41809202 41947057 42024183 42263532 42473830 42522177 42883857 42917025 43125839 43174389 43234762 43306394 43511369 43578086 43591491 43817350 43882676 43979525 44015553 44038712 44242938 44271803 44272337 44336157 44532540 44870100 44877978 45127611 45176729 45189758 46034050 46074258 46232463 46331814 46362364 46505903 46750314 46939295 47104416 47105867 47344773 47383136 47433676 47460662 47964275 48138217 48144587 48166252 48170321 48552975 48707125 48743383 49257078 49559329 50026968 50316901 50402009 50416680 50949115 50956849 51130769 51133404 51631799 51677937 51704625 51853633 51948352 52094388 52205054 52210501 52220908 52496098 52612183 53401955 53712550 53738255 53749064 53969245 53973944 54044734 54114942 54149260 54268718 54426699

3.75 6.33333 4 5.2 4.25 10.5 5 3.25 6 11.3333 7.25 14.5 4.66667 6 7.75 8 6 14.5 3 6 3.75 7 6 7 5.5 3.33333 10.5 5.5 5 6.75 4.33333 5 5.5 7 4.5 7.25 8.5 7 9 6.5 4.75 7.25 5.5 4.4 14.5 6.5 5 5.5 7.5 4 5.5 6 12 4.2 8 9 4.2 7.5 11 12 7.5 18 7.5 5.75 5.25 4.25 7.5 5 8.5 7 5.5 5.66667 9 5.5 8 5 8 3.75 4.5 9.66667 5 7.5 6.8 5.66667

ENSSSCT00000006669 . promoter . . intergenic ENSSSCT00000006674 LAPTM4B intron . . intergenic ENSSSCT00000034269CU302278.8 promoter ENSSSCT00000006678 . intron ENSSSCT00000006678 . intron ENSSSCT00000006678 . intron ENSSSCT00000006679 SDC2 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000006680 PTDSS1 intron ENSSSCT00000006681 MTERFD1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000006684 NDUFAF6 intron ENSSSCT00000006686 CCNE2 intron ENSSSCT00000006687 INTS8 intron ENSSSCT00000006687 INTS8 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000006700 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000006707 RUNX1T1 intron ENSSSCT00000006707 RUNX1T1 intron ENSSSCT00000006707 RUNX1T1 intron ENSSSCT00000006707 RUNX1T1 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000006708 SLC26A7 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

0.103 0.209 0.105 . 0.175 0.214 0.567 . 0.511 -0.06 0.236 . -0.19 1.029 0.229 . 0.224 0.099 0.256 0.251 -0.099 0.046 0.117 . 0.054 -0.009 0.369 0.226 -0.004 . 0.106 -0.166 0.088 0.152 0.051 0.131 0.115 . -0.075 -0.155 0.152 -0.042 -0.051 -0.001 . -0.186 0.013 0.056 -0.395 0.029 0.149 . 0.635 . . . -0.168 . -0.016 . . . . 0.223 0.209 0.19 0.021 0.11 . . -0.166 . . 0.024 0.114 0.243 -0.142 0.073 -0.009 . . 0.086 -0.041 .

. 080968 rs7873 644499 rs7872 192889 rs7873 rs790164653 rs792916576 rs789405615 rs789916649 rs793876679 120590 rs7922 779661 rs7903 rs787408333 rs790517324 rs788429201 rs790709224 . 845172 rs7909 541456 rs7919 . 041073 rs7895 rs790738441 . rs788693443 rs793076761 rs792228113 rs788519154 983169 rs7876 rs790010408 rs788412807 116691 rs7932 rs789521167 . rs786770046 rs788997259 rs791219738 680786 rs7901 rs786865395 618938 rs7909 rs791724381 . rs793712730 220084 rs7905 rs791802128 rs792512935 rs789585619 rs709744200 205980 rs7049 . 589055 rs7876 rs790249038 . . 458802 rs7937 rs790535997 395933 rs7881 775627 rs7929 rs788453395 . rs791752432 . 410204 rs7875 775625 rs7898 . rs712755880 167225 rs7896 875373 rs7891 rs790058093 rs786260529 rs791297126 . . 304290 rs7904 156301 rs7874 660901 rs7898 . . 674123 rs7864 . 384856 rs7930 582072 rs7873 rs788456743 590353 rs7875 623127 rs7871 389672 rs7937

2 2 2 2 3 4 2 2 2 2 2 2 2 2 4 3 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 3 2 2 3 2 2 2 3 2 2 3 2 3 4 4 4 2 2 4 2 2 2 2 2 2 3 2 2 3 3 4 2 2 2 3 2 2 4 4 2 3 3 3 4 2 2 2 2 2 3 2 2

AAAC.GTTT AATG.CATT AAAT.ATTT AT.AT AATG.CATT AAAC.GTTT AAAG.CTTT AG.CT AG.CT AC.GT AC.GT AT.AT AT.AT AT.AT AAT.ATT AT.AT AT.AT AC.GT ACAT.ATGT AC.GT AAAC.GTTT AAAC.GTTT AC.GT AAG.CTT AT.AT AAAC.GTTT AAC.GTT AAAC.GTTT AT.AT AG.CT AAC.GTT AC.GT AG.CT AAAC.GTTT AC.GT AT.AT AAAC.GTTT ATCC.GGAT AAAC.GTTT AG.CT AAAG.CTTT ATC.GAT AC.GT AAAAT.ATTTT AAAC.GTTT AT.AT AT.AT AAAAT.ATTTT AAAT.ATTT AC.GT AAAT.ATTT AAAT.ATTT AT.AT AAAAT.ATTTT AC.GT AC.GT AC.GT AC.GT AC.GT AAC.GTT AC.GT AAAC.GTTT AAT.ATT AC.GT AG.CT AT.AT AC.GT AAC.GTT AAAC.GTTT AAG.CTT AAC.GTT AAAC.GTTT ACATAT.ATATGT AAAT.ATTT AAAT.ATTT AC.GT ACAT.ATGT AG.CT AAAC.GTTT AAAAT.ATTTT AT.AT AAGG.CCTT AATT.AATT AAAT.ATTT

4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4

55078005 55155501 55157662 55185620 55860336 55949519 55984161 56001084 56015911 56106935 56261816 56263245 56600940 56710509 57013447 57082420 57511860 57639890 57656852 57665638 57684527 57724012 57732426 57987448 58085781 58337761 58355022 58371649 58462164 58651889 58750908 59412646 59498453 59530054 59585451 59832080 59928875 60024777 60195697 60468319 60518388 61011876 61019802 61037904 61247645 61285500 61285500 61423307 61437964 61513928 61588718 61735365 61890316 62098055 62220995 62220995 62220995 62220995 62220995 62262582 62399801 62459737 62875252 63184517 63250652 63357765 63401524 63412343 63916707 63955034 63967983 63996959 64205555 64425202 64435773 64445823 64484537 64550810 64577372 64585784 64633783 64641954 64806944 64822127

55078018 55155520 55157688 55185632 55860357 55949545 55984204 56001095 56015931 56106949 56261825 56263257 56600950 56710523 57013458 57082429 57511882 57639907 57656878 57665656 57684549 57724040 57732435 57987463 58085793 58337775 58355038 58371665 58462181 58651911 58750922 59412658 59498463 59530070 59585473 59832097 59928889 60024804 60195723 60468332 60518409 61011891 61019818 61037926 61247663 61285511 61285511 61423327 61437978 61513942 61588740 61735386 61890343 62098077 62221020 62221020 62221020 62221020 62221020 62262607 62399812 62459755 62875266 63184549 63250687 63357779 63401535 63412365 63916730 63955046 63967995 63996973 64205579 64425221 64435810 64445845 64484548 64550820 64577386 64585810 64633795 64641974 64806965 64822151

3.5 5 6.75 6.5 5.5 6.75 11 6 10.5 7.5 5 6.5 5.5 7.5 4 5 11.5 9 6.75 9.5 5.75 7.25 5 5.33333 6.5 3.75 5.66667 4.25 9 11.5 5 6.5 5.5 4.25 11.5 9 3.75 7 6.75 7 5.5 5.33333 8.5 4.6 4.75 6 6 4.2 3.75 7.5 5.75 5.5 14 4.6 13 13 13 13 13 8.66667 6 4.75 5 16.5 18 7.5 6 7.66667 6 4.33333 4.33333 3.75 4.16667 5 9.5 11.5 3 5.5 3.75 5.4 6.5 5.25 5.5 6.25

. . intergenic ENSSSCT00000006727 CNGB3 intron ENSSSCT00000006727 CNGB3 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000006742 RALYL intron . . intergenic ENSSSCT00000025498 . intron ENSSSCT00000025498 . intron ENSSSCT00000025498 . intron ENSSSCT00000025498 . intron ENSSSCT00000025498 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000029360 ZBTB10 intron ENSSSCT00000006749 ZBTB10 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000006752 MRPS28 intron . . intergenic ENSSSCT00000035189 STMN2 intron ENSSSCT00000006754 STMN2 intron ENSSSCT00000036553 STMN2 intron ENSSSCT00000033041 STMN2 intron ENSSSCT00000032694 STMN2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

. 0.064 . 0.287 0.057 0.122 0.023 0.12 0.074 -0.291 -0.126 -0.036 . . -0.142 . . 0.086 0.001 . -0.134 -0.106 0.018 -0.088 . 0.025 -0.058 0.012 . . 0.034 -0.029 0.11 0.12 -0.098 . 0.231 0.12 . -0.154 -0.152 -0.085 -0.145 . 0.187 0.086 0.086 -0.205 0.182 0.182 -0.021 -0.129 0.023 0.046 0.592 0.592 0.592 0.592 0.592 . -0.085 0.008 0.04 0.038 0.02 0.068 -0.013 -0.121 0.156 -0.179 . . 1.795 . 0.096 0.36 -0.194 -0.143 . 0.081 0.091 0.082 -0.217 0.267

rs789724700 rs790843583 052749 rs7884 189872 rs7873 578708 rs7897 rs788203272 rs791136500 773140 rs7916 442650 rs7891 rs790911834 . 976790 rs7901 rs788251980 104605 rs7878 rs791625629 rs790344886 . 297614 rs7869 rs792433616 rs787007337 541947 rs7870 rs786396229 . 431090 rs7895 rs791606032 rs791064930 585054 rs7925 rs793001881 rs793184789 rs705920180 rs793132468 . . rs793469006 rs787508529 . 506142 rs7894 . rs790885019 252769 rs7914 rs787386957 . 491323 rs7876 rs788797221 787072 rs7864 rs790892746 rs790892746 rs793543315 rs791870482 rs787090840 909701 rs7916 830648 rs7920 . 289518 rs7914 516993 rs7922 516993 rs7922 516993 rs7922 516993 rs7922 516993 rs7922 334921 rs7930 rs791950094 rs786649829 rs792171427 510175 rs7889 rs706664001 rs788988351 rs786302516 rs787333275 187177 rs7921 rs790508067 rs792591159 rs788650448 rs792986938 rs791741543 rs787185404 . . rs792626519 rs790975967 539955 rs7883 rs787397896 119271 rs7915 rs792760403 rs791639481

2 2 2 2 2 2 2 2 4 2 2 3 3 2 2 3 2 5 3 3 4 2 2 2 4 2 2 2 2 3 2 3 4 2 3 2 2 4 2 2 2 3 2 2 2 2 2 2 3 3 2 2 4 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 3 2 3 2 2 2 2 2 2 2 2 2 3 2 2 2

AT.AT AC.GT ACC.GGT AC.GT AG.CT AAAT.ATTT AC.GT AC.GT AT.AT AC.GT AT.AT AC.GT AAAC.GTTT AC.GT AAAC.GTTT AC.GT AC.GT AAAT.ATTT AC.GT AAAAC.GTTTT AAAAC.GTTTT AAAG.CTTT AAAG.CTTT AAAC.GTTT AC.GT AAAT.ATTT AAT.ATT AAAC.GTTT AAAG.CTTT AC.GT AAAT.ATTT AG.CT AAAAC.GTTTT AC.GT AT.AT AAGG.CCTT AT.AT AAAAT.ATTTT AC.GT AAC.GTT AGG.CCT AT.AT AAAT.ATTT AAAC.GTTT AG.CT AT.AT AT.AT AT.AT AC.GT AAT.ATT AAAG.CTTT AAAG.CTTT AAAC.GTTT AAAC.GTTT AC.GT AC.GT AC.GT AT.AT AT.AT AAAC.GTTT AT.AT AAAAAC.GTTTTT AAT.ATT AG.CT AG.CT AG.CT AATT.AATT AATT.AATT ACAT.ATGT AG.CT AAAC.GTTT AC.GT AC.GT AT.AT ACC.GGT AAT.ATT AC.GT AT.AT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAG.CTTT AAAT.ATTT

4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4

64937515 65258670 65592147 65995479 66197460 66387498 66517051 66912417 66958113 66998827 67008794 67046214 67103020 67149108 67195843 67240957 67512177 67596527 67597519 67630599 67630599 67646001 67646001 67686701 67689449 67765138 67807958 67814830 67819354 67881440 67918929 68106396 68126871 68565520 68589281 68836041 69253653 69358023 69383931 69501220 69581229 69621226 69823345 69837097 69873988 69885041 70172233 70189172 70234140 70352905 70480592 70982450 71012904 71232755 71368951 71396331 72033786 72337357 72564757 72579652 72587082 72625341 72632382 73131717 73354788 73354788 73365748 73365748 73470743 73481119 73506788 73652963 73652963 73923573 74373197 74493291 74630835 74961051 75022732 75023101 75155499 75183321 75717084 75927713

64937524 65258685 65592159 65995491 66197472 66387511 66517071 66912426 66958127 66998837 67008804 67046230 67103035 67149118 67195864 67240977 67512199 67596541 67597528 67630621 67630621 67646019 67646019 67686729 67689458 67765157 67807970 67814842 67819366 67881454 67918948 68106425 68126899 68565538 68589291 68836082 69253664 69358039 69383952 69501233 69581245 69621235 69823365 69837115 69874002 69885059 70172249 70189183 70234165 70352916 70480609 70982478 71012923 71232777 71368966 71396343 72033806 72337366 72564769 72579669 72587100 72625372 72632394 73131728 73354797 73354797 73365761 73365761 73470761 73481133 73506807 73652977 73652977 73923591 74373210 74493302 74630854 74961062 75022748 75023123 75155520 75183350 75717098 75927738

5 8 4.33333 6.5 6.5 3.5 10.5 5 7.5 5.5 5.5 8.5 4 5.5 5.5 10.5 11.5 3.75 5 4.6 4.6 4.75 4.75 7.25 5 5 4.33333 3.25 3.25 7.5 5 15 5.8 9.5 5.5 10.5 6 3.4 11 4.66667 5.66667 5 5.25 4.75 7.5 9.5 8.5 6 13 4 4.5 7.25 5 5.75 8 6.5 10.5 5 6.5 4.5 9.5 5.33333 4.33333 6 5 5 3.5 3.5 4.75 7.5 5 7.5 7.5 9.5 4.66667 4 10 6 4.25 5.75 5.5 7.5 3.75 6.5

ENSSSCT00000006763 . . . . . . . . . . . . . ENSSSCT00000006767 . . . . ENSSSCT00000035167 ENSSSCT00000006769 ENSSSCT00000006769 ENSSSCT00000035167 . ENSSSCT00000006770 ENSSSCT00000006771 . . . . . . . . . . ENSSSCT00000006780 . . . . . . . . . . . . ENSSSCT00000006786 . . . ENSSSCT00000006791 ENSSSCT00000006792 ENSSSCT00000006792 . . . . . . . ENSSSCT00000034412 ENSSSCT00000006795 ENSSSCT00000034412 ENSSSCT00000006795 ENSSSCT00000034412 . . . ENSSSCT00000006796 ENSSSCT00000035957 ENSSSCT00000006800 ENSSSCT00000032451 . . . . . ENSSSCT00000006816 . . ENSSSCT00000031830

ZFHX4 . . . . . . . . . . . . . GDAP1 . . . . MD-2 MD-2 MD-2 MD-2 . TCEB1 . . . . . . . . . . . . . . . . . . . . . . . . LACTB2 . . . SLCO5A1 SULF1 SULF1 . . . . . . . CPA6 CPA6 CPA6 CPA6 CPA6 . . . ARFGEF1 ARFGEF1 MCMDC2 C8orf46 . . . . . ARMC1 . . .

intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intron intron intron intron intergenic promoter intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intron

0.074 0.125 -0.081 1.024 -0.025 0.175 -0.337 0.631 . 0.06 . 0.13 . 0.16 . 0.114 . . -0.038 . . 0.426 0.426 0.208 0.319 0.358 . -0.012 . . 0.054 0.336 . 0.044 . . 0.049 -0.306 . -0.218 -0.281 0.59 0.077 . 0.452 0.232 . 0.015 . 0.327 0.322 0.067 . 0.026 -0.008 0.211 . 0.085 0.331 0.048 0.364 0.047 . 0.009 0.408 0.408 . . 0.01 -0.298 -0.049 0.044 0.044 0.368 -0.047 . 0.041 0.285 . . . 0.7 2.031 -0.018

. 410744 rs7881 rs788446138 rs790388685 958355 rs7921 rs786514647 . rs789713290 rs790060720 rs792991092 rs787784436 rs791001633 rs793363165 rs792020106 rs792952822 764370 rs7893 720554 rs7938 rs790873196 . rs793448898 rs793448898 rs792057885 rs792057885 . rs789254298 rs791973344 rs791378816 . . rs789318612 rs790690157 rs787530036 rs787622100 391419 rs7882 rs786336742 rs789480682 766862 rs7914 . rs788057312 rs790937791 028223 rs7935 . rs787899194 rs789719638 rs786759634 rs786663566 rs788717871 . . . rs790631591 834581 rs7916 rs788684339 rs790374917 986263 rs7908 rs790567437 671179 rs7932 rs792302027 935116 rs7900 rs789812612 653686 rs7866 rs788973644 . rs787386044 rs705285566 rs705285566 rs786854835 rs786854835 rs788317004 rs793378025 rs792239294 rs705284403 rs705284403 rs789966123 . rs786390115 675808 rs7888 rs792179032 rs791365378 rs788072529 rs790457173 rs789367345 rs788996072 rs786386554

4 2 2 3 2 2 3 2 2 2 2 3 2 2 2 4 5 2 2 2 2 2 2 2 2 2 2 2 3 6 2 2 2 3 2 2 2 2 4 2 2 2 3 2 3 2 2 3 4 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 3 3 2 2 2 2 2 2 2 2 2 2 4

AAC.GTT AATT.AATT AAAAC.GTTTT AAAC.GTTT AG.CT AAAAAC.GTTTTT AAAT.ATTT AAGAG.CTCTT AG.CT AG.CT AC.GT AC.GT AG.CT AAAAC.GTTTT AT.AT AC.GT AAAG.CTTT AT.AT AAAC.GTTT AC.GT AAT.ATT ACATAT.ATATGT AAGG.CCTT AG.CT AAAC.GTTT AAAT.ATTT AAC.GTT AAAT.ATTT AGAT.ATCT AATG.CATT AAAC.GTTT AT.AT AG.CT AT.AT ACAGAT.ATCTGT AAAC.GTTT AC.GT AAT.ATT AAAAC.GTTTT AC.GT AAAAC.GTTTT AAAC.GTTT AAAAC.GTTTT AT.AT AAAC.GTTT AAAT.ATTT AC.GT AAC.GTT AAT.ATT AAT.ATT AAC.GTT AAC.GTT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AAC.GTT AAAC.GTTT AC.GT AAGC.GCTT AAG.CTT AAAT.ATTT AT.AT AG.CT ACCT.AGGT AC.GT AAAC.GTTT AAAT.ATTT AAT.ATT AG.CT AAAC.GTTT AT.AT AC.GT AAAG.CTTT AC.GT AAACT.AGTTT AC.GT AT.AT AG.CT AC.GT AC.GT AAATG.CATTT AAG.CTT AC.GT AAAC.GTTT

4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4

76000829 76031549 76146136 76338094 76542754 76776727 76812951 77185759 77362501 77387152 77393689 77402946 77405499 77406742 77718097 77733984 77791535 78124810 78132090 78231685 78480311 78486494 78498919 78574050 78590366 78630452 78662583 78806869 78853475 78930287 79062249 79411781 80254646 80257507 80333863 80756320 81168813 81244253 81263103 81340467 81496043 81568631 81574908 81775446 81788301 81925100 82058963 82177263 82245326 82303988 82305537 82340910 82434397 82519637 82546349 82708163 82751583 82917915 82928812 83041881 83134114 83232668 83482960 83614213 83774484 84049000 84101210 84433036 84503313 84633110 85011277 85011358 85266985 85424877 85624382 85624920 86509775 86510924 86680384 86768973 87013290 87329329 87549352 87823194

76000853 76031579 76146155 76338117 76542772 76776760 76812965 77185782 77362512 77387163 77393705 77402961 77405515 77406767 77718108 77733994 77791572 78124819 78132122 78231695 78480332 78486513 78498937 78574062 78590380 78630482 78662603 78806883 78853491 78930316 79062273 79411797 80254656 80257516 80333890 80756345 81168825 81244270 81263119 81340479 81496060 81568649 81574927 81775455 81788323 81925126 82058975 82177282 82245346 82304004 82305550 82340929 82434432 82519670 82546361 82708185 82751596 82917926 82928836 83041892 83134137 83232679 83482973 83614228 83774496 84049025 84101225 84433057 84503324 84633124 85011291 85011372 85267013 85424888 85624402 85624929 86509784 86510935 86680394 86768993 87013308 87329340 87549371 87823210

8.33333 7.75 4 6 9.5 5.66667 3.75 4.8 6 6 8.5 8 8.5 5.2 6 5.5 9.5 5 8.25 5.5 7.33333 3.33333 4.75 6.5 3.75 7.75 7 3.75 4.25 7.5 6.25 8.5 5.5 5 4.66667 6.5 6.5 6 3.4 6.5 3.6 4.75 4 5 5.75 6.75 6.5 6.66667 7 5.66667 4.66667 6.66667 7.2 8.5 3.25 7.66667 3.5 6 6.25 4 6 6 7 4 6.5 6.5 4 7.33333 6 3.75 7.5 7.5 7.25 6 4.2 5 5 6 5.5 10.5 3.8 4 10 4.25

. . . . . . . . . . . . . . . . ENSSSCT00000020920 . . . ENSSSCT00000028806 ENSSSCT00000028806 ENSSSCT00000028806 ENSSSCT00000006827 ENSSSCT00000006827 ENSSSCT00000006827 . . . . ENSSSCT00000006828 . . . . ENSSSCT00000006832 . . . . . . . . . . . . . . . . . . . . ENSSSCT00000006849 ENSSSCT00000006851 ENSSSCT00000006851 . . . . . . . . . . . . . . . . . . . ENSSSCT00000006869 . . ENSSSCT00000006873 ENSSSCT00000006876 .

. . . . . . . . . . . . . . . . U6 . . . . . . CLVS1 CLVS1 CLVS1 . . . . CHD7 . . . . TOX . . . . . . . . . . . . . . . . . . . . LYN . . . . . . . . . . . . . . . . . . . . . SNAI2 . . PRKDC SPIDR .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic exon intergenic intergenic intergenic intron intron intron intron intron intron intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic promoter intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic cds intergenic intergenic intron intron intergenic

0.846 0.143 0.235 . 0.204 0.156 . 0.09 0.101 0.198 0.038 0.015 . . . . -0.006 -0.073 . 0.096 -0.193 0.118 0.052 . 0.013 0.198 0.187 0.078 -0.156 0.067 0.006 . -0.175 0.401 -0.107 0.448 . 0.119 0.307 -0.001 -0.172 -0.109 -0.22 -0.047 -0.168 . -0.01 -0.078 0.099 0.034 . 0.114 0.143 0.389 -0.092 0.082 -0.002 . 0.019 0.074 -0.001 -0.045 . 0.301 0.127 -0.235 -0.019 0.085 -0.235 -0.02 0.038 0.062 . 0.067 -0.03 -0.141 0.078 0.078 1.388 0.522 0 0.077 0.297 .

896617 rs7867 rs791943543 . rs790266601 800038 rs7924 rs793551142 621914 rs7882 rs792044911 rs790235620 771388 rs7926 . . rs697829498 rs793014921 . . rs791274123 rs788986480 066805 rs7910 rs790134924 rs790108025 rs791719738 451822 rs7897 . rs792363867 . rs787259919 . rs791027929 rs786284797 rs791777595 rs793014430 rs787980390 rs792277190 . rs792492372 rs793325325 rs788653026 rs786865829 rs786375036 rs791710636 rs792273484 rs788878242 rs787849321 553543 rs7867 rs792528956 . 199044 rs7884 rs709999110 rs790849375 rs791917291 rs793449986 rs792830818 rs787644951 rs792446379 rs788756505 rs788920120 rs790038123 . 928454 rs7887 018933 rs7907 804627 rs7896 rs793470337 . . rs787168752 520020 rs7887 . rs787908390 rs788378730 . rs792808921 rs792680446 . 255508 rs7880 rs793710280 rs790849629 rs787543531 . . rs788681442 rs790470818 rs790259410 .

2 2 2 2 6 2 2 2 3 2 4 2 3 2 3 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 3 2 2 4 2 2 2 2 2 2 2 3 4 2 4 2 4 3 4 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 4

AT.AT AAAC.GTTT AG.CT AAAAAT.ATTTTT AAC.GTT AAAAC.GTTTT AT.AT AATG.CATT AT.AT AAG.CTT AAG.CTT AAAT.ATTT AAAT.ATTT AAT.ATT AAT.ATT AAT.ATT AAAAAT.ATTTTT AAAC.GTTT AC.GT AAAAC.GTTTT AG.CT AAAAT.ATTTT AC.GT AAAAT.ATTTT AAAT.ATTT AT.AT AAC.GTT AAAAG.CTTTT AAAC.GTTT AAC.GTT AAAT.ATTT AAAG.CTTT AAAAC.GTTTT AAG.CTT AATT.AATT AAAT.ATTT AAG.CTT AAAC.GTTT AC.GT AAAT.ATTT AAC.GTT AG.CT AT.AT AGG.CCT AAT.ATT AAAT.ATTT AT.AT AAC.GTT AC.GT AAAAT.ATTTT AAAT.ATTT AAT.ATT AAT.ATT AT.AT AC.GT AC.GT AAAC.GTTT AAAAT.ATTTT AAAT.ATTT AATC.GATT AT.AT AG.CT AC.GT AT.AT AC.GT AT.AT AG.CT AAAT.ATTT AC.GT AAAC.GTTT AT.AT AAAC.GTTT AT.AT AAAC.GTTT AC.GT AAAAG.CTTTT AC.GT AAAAAG.CTTTTT AAAC.GTTT AAAC.GTTT AC.GT AAC.GTT AT.AT AC.GT

4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4

88031336 88108869 88417235 88468842 88622432 88754552 88811832 88811992 88822704 88991797 88991797 88993023 88993023 89012472 89012472 89012472 89335165 89409028 89415724 89471891 89477755 89506804 89587013 89738240 89738446 89945509 90091399 90258733 90376294 90487976 90768058 90796553 90864021 90914520 90998901 91091752 91265549 91517032 91715067 91721044 91737496 91910871 91930446 92268259 92336124 92628290 92661199 92664872 92857935 92963272 92971174 93035849 93035849 93105835 93175685 93223485 93321105 93353587 93548383 93960329 93966186 93971442 93982967 93993864 94036235 94374878 94415681 94422436 94467880 94489927 94671909 94747557 94753511 94771725 94896356 95042931 95052713 95093878 95182097 95337025 95372204 95457929 95495137 95702637

88031346 88108889 88417244 88468861 88622446 88754570 88811860 88812008 88822728 88991808 88991808 88993041 88993041 89012483 89012483 89012483 89335192 89409051 89415746 89471912 89477771 89506821 89587033 89738263 89738460 89945525 90091413 90258753 90376305 90487996 90768076 90796572 90864051 90914535 90998926 91091772 91265566 91517059 91715091 91721061 91737509 91910882 91930474 92268271 92336144 92628324 92661208 92664897 92857946 92963290 92971201 93035863 93035863 93105844 93175696 93223497 93321125 93353610 93548406 93960351 93966197 93971451 93982977 93993874 94036245 94374888 94415708 94422454 94467894 94489946 94671924 94747568 94753520 94771763 94896370 95042958 95052723 95093899 95182129 95337058 95372213 95457949 95495156 95702652

5.5 5.25 5 3.33333 5 3.8 14.5 4.25 12.5 4 4 4.75 4.75 4 4 4 4.66667 6 11.5 4.4 8.5 3.6 10.5 4.8 3.75 8.5 5 4.2 3 7 4.75 5 6.2 5.33333 6.5 5.25 6 7 12.5 4.5 4.66667 6 14.5 4.33333 7 8.75 5 8.66667 6 3.8 7 5 5 5 6 6.5 5.25 4.8 6 5.75 6 5 5.5 5.5 5.5 5.5 14 4.75 7.5 5 8 3 5 9.75 7.5 5.6 5.5 3.66667 8.25 8.5 5 7 10 8

. . . . ENSSSCT00000006882 . ENSSSCT00000006884 ENSSSCT00000006884 ENSSSCT00000006884 ENSSSCT00000006891 ENSSSCT00000036036 ENSSSCT00000006891 ENSSSCT00000036036 ENSSSCT00000036036 ENSSSCT00000006891 ENSSSCT00000035164 ENSSSCT00000006898 . . . . . . . . . . . . . . ENSSSCT00000006910 ENSSSCT00000006910 ENSSSCT00000006911 ENSSSCT00000006912 . . . ENSSSCT00000006923 ENSSSCT00000006923 . ENSSSCT00000006926 . . ENSSSCT00000006928 ENSSSCT00000006931 ENSSSCT00000006931 ENSSSCT00000006931 ENSSSCT00000027133 . . ENSSSCT00000006936 ENSSSCT00000033501 . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000006941 ENSSSCT00000006942 ENSSSCT00000006942 . . . . . . .

. . . . KIFAP3 . C1orf112 C1orf112 C1orf112 SELP SELP SELP SELP SELP SELP SELP NME7 . . . . . . . . . . . . . . ADCY10 ADCY10 MPZL1 RCSD1 . . . . . . POGK . . FAM78B TMCO1 TMCO1 TMCO1 LRRC52 . . RXRG RXRG . . . . . . . . . . . . . . . . . . . . . NUF2 RGS5 RGS5 . . . . . . .

intergenic intergenic intergenic intergenic intron intergenic intron intron intron intron intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron 3'utr intergenic intergenic intergenic promoter intron intergenic intron intergenic intergenic intron intron intron intron intron intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron 3'utr intergenic intergenic intergenic intergenic intergenic intergenic intergenic

-0.033 0.137 -0.072 . 0.104 . 0.092 0.19 0.309 0.082 0.082 0.119 0.119 0.13 0.13 0.13 -0.048 . . . . . . . -0.044 -0.079 -0.113 . . 0.188 0.218 0.015 -0.392 0.004 -0.12 . 0.46 -0.037 . . . 0.779 0.164 . . 0.109 0.172 -0.029 0.046 0.107 0.404 -0.003 -0.003 0 0.115 -0.006 . . -0.147 0.253 0.028 -0.067 . -0.105 0.617 . 1.47 -0.068 -0.04 0.002 . 0.009 0.027 0.211 . 0.038 0.098 . -0.114 . 0.057 -0.031 . -0.258

. rs787714106 rs789065087 . . rs791632931 rs793683184 . rs791128782 rs789359555 rs789359555 rs790854616 rs790854616 . . . rs790334025 345362 rs7868 rs793762164 rs792925704 rs790076869 rs791313268 . 668063 rs7894 rs792172536 . rs713488607 rs793090798 rs791091989 . rs789927264 rs793058620 rs788313252 rs793008061 rs792027788 rs793303659 394951 rs7921 rs788653903 rs787988874 rs788539225 rs787976200 rs788601207 . 439846 rs7915 rs787539666 rs793081998 . . . rs792607926 159936 rs7913 rs786470010 rs786470010 rs791034991 . rs790582539 rs787804878 rs793539293 039117 rs7901 rs790060932 rs787565532 rs790219847 451522 rs7873 rs789464046 . rs793425999 rs788598611 rs786568166 995133 rs7866 341726 rs7910 521804 rs7928 rs787352350 rs792789597 594735 rs7937 rs786726779 058224 rs7912 182135 rs7917 703994 rs7864 rs787847532 rs695474459 . rs789313766 rs789035432 842812 rs7927

2 2 3 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 7 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 3 2 4 2 2 2 3 2 2 2 2 4 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 5 2 2 3 2 2 2 2 2 2 4 2 2 2 3 2 2 2

AC.GT AT.AT AT.AT AC.GT AC.GT AAT.ATT AG.CT AG.CT AG.CT AG.CT AG.CT AG.CT AG.CT AT.AT AC.GT AC.GT AC.GT AC.GT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAGG.CCTT AC.GT AT.AT ACC.GGT AAAAC.GTTTT AC.GT AAAC.GTTT AC.GT AG.CT AAAT.ATTT AT.AT AAAC.GTTT AC.GT AC.GT AC.GT AAAC.GTTT AG.CT AAG.CTT AAAAAT.ATTTTT AC.GT AAAC.GTTT AT.AT AAAAC.GTTTT AAAAC.GTTTT AAAAC.GTTTT AAAC.GTTT AAAAAC.GTTTTT AAAC.GTTT AAAAT.ATTTT AG.CT AAC.GTT AC.GT AAC.GTT AAAC.GTTT AAAC.GTTT AC.GT AAAT.ATTT AT.AT AAAAT.ATTTT AC.GT AG.CT AAAC.GTTT AG.CT AG.CT AAAAC.GTTTT AG.CT AT.AT AG.CT AG.CT AAAC.GTTT AAAC.GTTT AT.AT AG.CT AAAT.ATTT AAAT.ATTT AAC.GTT AAAG.CTTT AAAG.CTTT AAAC.GTTT AT.AT AAT.ATT AAAC.GTTT AATT.AATT

4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4

95970588 96194910 96275614 96302958 96522030 96868587 96901669 96901669 96901669 96901669 96901669 96901669 96901669 97056643 97330624 97330624 97355223 97370994 97532675 97532675 97532675 97622363 97737192 98734458 98928833 98961477 99054937 99064897 99134239 99365376 99529983 99540169 100458847 100541776 100541776 100541776 100711556 100825631 101034488 101518025 101557538 101788297 101871516 101983084 101983084 101983084 102189331 102264266 102424923 102441185 102472088 102908819 103367631 103368694 103719802 103867239 104029472 104524511 104552053 104566884 104726401 105028813 105204768 105471617 105675766 105681763 105705992 106066459 106091412 106122980 106267788 106586230 106664459 106674642 106703909 106703909 107322105 107429908 107667696 107699311 109034393 109036290 109038160 109040867

95970599 96194920 96275623 96302968 96522043 96868603 96901713 96901713 96901713 96901713 96901713 96901713 96901713 97056656 97330638 97330638 97355238 97371003 97532693 97532693 97532693 97622380 97737205 98734468 98928852 98961503 99054968 99064911 99134249 99365390 99530004 99540179 100458861 100541789 100541789 100541789 100711584 100825645 101034501 101518045 101557549 101788325 101871531 101983105 101983105 101983105 102189353 102264298 102424950 102441206 102472098 102908833 103367644 103368710 103719820 103867253 104029481 104524533 104552077 104566899 104726417 105028823 105204782 105471627 105675777 105681787 105706019 106066468 106091423 106122994 106267802 106586247 106664468 106674652 106703933 106703933 107322129 107429928 107667710 107699322 109034408 109036308 109038174 109040878

6 5.5 5 5.5 7 5.66667 22.5 22.5 22.5 22.5 22.5 22.5 22.5 7 7.5 7.5 8 5 4.75 4.75 4.75 4.5 7 5.5 6.66667 5.4 16 3.75 5.5 7.5 5.5 5.5 3.75 7 7 7 7.25 7.5 4.66667 3.5 6 7.25 8 4.4 4.4 4.4 5.75 5.5 7 4.4 5.5 5 7 5.66667 4.75 3.75 5 5.75 12.5 3.2 8.5 5.5 3.75 5.5 6 5 14 5 6 7.5 3.75 4.5 5 5.5 6.25 6.25 8.33333 5.25 3.75 3 8 6.33333 3.75 3

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000006957 . intron ENSSSCT00000033832 CD32 intron ENSSSCT00000033848 CD32 intron ENSSSCT00000006958 CD32 intron ENSSSCT00000033401 CD32 intron ENSSSCT00000006959 CD32 intron ENSSSCT00000031531 CD32 intron ENSSSCT00000035271 CD32 intron . . intergenic ENSSSCT00000006979 F11R intron ENSSSCT00000033820 F11R intron . . intergenic . . intergenic ENSSSCT00000034681 LY9 intron ENSSSCT00000006986 LY9 intron ENSSSCT00000036000 LY9 intron ENSSSCT00000006984 . promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000035228 CD1D intron ENSSSCT00000033538 KIRREL intron ENSSSCT00000007068 KIRREL intron ENSSSCT00000036287 KIRREL intron . . intergenic ENSSSCT00000007074 FCRL3 intron . . intergenic ENSSSCT00000007078 ARHGEF11 intron ENSSSCT00000007078 ARHGEF11 intron . . intergenic ENSSSCT00000007084 PRCC intron ENSSSCT00000007091 . promoter ENSSSCT00000027298 . promoter ENSSSCT00000031509 . promoter . . intergenic . . intergenic . . intergenic ENSSSCT00000007106 CCT3 intron ENSSSCT00000007109 SMG5 intron ENSSSCT00000028079 . intron ENSSSCT00000007143 GBA intron ENSSSCT00000007143 GBA intron ENSSSCT00000007166 KCNN3 intron ENSSSCT00000007166 KCNN3 intron ENSSSCT00000007170 CHRNB2 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000007189 GATAD2B intron . . intergenic ENSSSCT00000030953 PGLYRP3 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000007253 SNX27 promoter ENSSSCT00000007253 SNX27 intron ENSSSCT00000007253 SNX27 intron ENSSSCT00000023541 SNORD112 promoter ENSSSCT00000007266 VPS72 intron ENSSSCT00000007274 CDC42SE1 intron ENSSSCT00000007284 CTSS intron ENSSSCT00000007285 HORMAD1 intron ENSSSCT00000023324 LIX1L intron ENSSSCT00000023324 LIX1L intron ENSSSCT00000023324 LIX1L intron ENSSSCT00000023324 LIX1L intron

. . 0.006 -0.135 -0.239 -0.038 -0.348 -0.348 -0.348 -0.348 -0.348 -0.348 -0.348 . . . . -0.019 0.078 0.078 0.078 . 0.223 0.198 -0.059 -0.317 -0.046 . -0.067 -0.221 0.048 . . -0.212 -0.212 -0.212 -0.036 . . -0.015 -0.108 -0.207 0.257 -0.034 -0.034 -0.034 . -0.189 . 0.086 0.239 0.099 -0.215 . -0.226 -0.075 -0.023 . 0.937 0.604 . . . . . -0.009 0.12 . 0.02 0.094 0.029 0.281 0.683 0.178 . . 0.148 0.221 -0.061 0.389 0.093 0.458 0.429 0.258

464923 rs7918 680277 rs7926 rs792968449 . 342024 rs7866 957409 rs7882 428341 rs7897 428341 rs7897 428341 rs7897 428341 rs7897 428341 rs7897 428341 rs7897 428341 rs7897 . rs712139257 rs712139257 252415 rs7871 rs787426485 rs793218981 rs793218981 rs793218981 100339 rs7091 412844 rs7892 rs787290926 rs791774658 rs786360782 . rs791217755 . rs788673186 rs791486968 rs792580102 rs787616185 . . . rs694080126 124296 rs7905 238106 rs7876 rs790652761 rs792463940 rs789472489 rs792310514 673463 rs7887 673463 rs7887 673463 rs7887 rs792899737 rs787642295 . rs790235469 764441 rs7937 rs792003574 rs791456973 rs792493183 504372 rs7893 rs788048366 rs788715561 rs789048763 rs787940527 rs787923303 rs788246383 rs791150422 999583 rs7903 rs704917131 rs787287577 rs786222043 381308 rs7875 . rs789665474 900876 rs7864 831452 rs7920 rs789902976 . rs788490784 039997 rs7907 039997 rs7907 rs789598391 rs786233235 rs793065801 rs792621973 081791 rs7935 806521 rs7911 rs698164247 rs790237818

2 2 2 3 2 2 4 4 4 4 4 4 4 3 2 2 3 2 2 2 2 2 4 2 2 2 2 2 3 3 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 3 2 3 4 2 4 2 2 3 2 3 2 2 2 2 2 2 2 2 4 2 2 2 2 3 3 2 2 3 2 2 2 3 2 2 2

AT.AT AAAT.ATTT AG.CT AG.CT ACAT.ATGT AAAC.GTTT AG.CT AC.GT AAAAC.GTTTT AAAG.CTTT AT.AT AC.GT AC.GT AT.AT AAAAC.GTTTT AG.CT AC.GT AC.GT AG.CT AC.GT AC.GT AC.GT AC.GT AAG.CTT AAC.GTT AG.CT AG.CT AG.CT AG.CT AC.GT AC.GT AC.GT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAG.CTT AC.GT AT.AT AT.AT AAAC.GTTT AC.GT AGG.CCT AC.GT ACAT.ATGT AT.AT AC.GT AGCATG.CATGC AC.GT AC.GT AG.CT AAAT.ATTT AAAT.ATTT AC.GT AC.GT AG.CT AGAT.ATCT AAC.GTT AAGG.CCTT AGAT.ATCT AGAT.ATCT AAAC.GTTT AAAC.GTTT AG.CT AAAAT.ATTTT AC.GT AT.AT AAT.ATT AT.AT AAAG.CTTT AAAC.GTTT AAAC.GTTT AC.GT AG.CT AG.CT AG.CT AG.CT AATT.AATT AAAC.GTTT AAAC.GTTT AT.AT AC.GT AAAAG.CTTTT AC.GT AAAAAT.ATTTTT

4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4

109604035 109720078 109785395 110018443 110123859 110196509 110556588 110738323 110747231 111554182 111801723 111816928 111936770 112054351 112056862 112289429 112383988 112401210 112586713 112710974 112710974 112981985 113236104 113328567 113376136 113687693 113687693 113687693 113687693 113693351 113693351 113693351 113695368 113695368 113695368 114106232 114290959 114534681 114536321 114636022 114751515 114776400 114799616 114807118 114987885 114992113 114993789 115451806 115693291 115742501 115791225 116046098 116233201 116449759 116486093 116504917 116535374 116544878 116794646 116794646 116881116 116881116 116980046 116982463 117020844 117122962 117130759 117352251 117357889 117370425 117590865 117597719 118022451 118425469 118552877 118662543 119065858 119418293 119418293 119427784 119644119 119660611 119735311 120198453

109604045 109720094 109785405 110018453 110123877 110196529 110556598 110738333 110747249 111554206 111801736 111816940 111936783 112054361 112056878 112289456 112384003 112401222 112586723 112710985 112710985 112982018 113236116 113328581 113376148 113687708 113687708 113687708 113687708 113693361 113693361 113693361 113695391 113695391 113695391 114106254 114290976 114534692 114536333 114636043 114751535 114776413 114799636 114807135 114987896 114992134 114993811 115451833 115693306 115742515 115791249 116046124 116233217 116449768 116486105 116504944 116535405 116544895 116794670 116794670 116881139 116881139 116980061 116982481 117020855 117122972 117130778 117352261 117357903 117370451 117590884 117597729 118022467 118425500 118552890 118662553 119065873 119418309 119418309 119427794 119644132 119660629 119735339 120198475

5.5 4.25 5.5 5.5 4.75 5.25 5.5 5.5 3.8 6.25 7 6.5 7 5.5 3.4 14 8 6.5 5.5 6 6 17 6.5 5 4.33333 8 8 8 8 5.5 5.5 5.5 6 6 6 7.66667 9 6 6.5 5.5 10.5 4.66667 10.5 4.5 6 11 3.83333 14 8 7.5 6.25 6.75 8.5 5 6.5 7 10.6667 4.5 6.25 6.25 6 6 8 3.8 6 5.5 6.66667 5.5 3.75 6.75 5 5.5 8.5 16 7 5.5 4 4.25 4.25 5.5 7 3.8 14.5 3.83333

. . . . ENSSSCT00000007340 ENSSSCT00000007341 ENSSSCT00000007347 . . . ENSSSCT00000007362 ENSSSCT00000007362 . . . . . . . ENSSSCT00000007368 ENSSSCT00000007367 . ENSSSCT00000007372 ENSSSCT00000007372 . ENSSSCT00000035345 ENSSSCT00000033361 ENSSSCT00000033366 ENSSSCT00000007377 ENSSSCT00000035345 ENSSSCT00000033361 ENSSSCT00000033366 ENSSSCT00000035345 ENSSSCT00000033361 ENSSSCT00000033366 ENSSSCT00000007380 . . . . . ENSSSCT00000007388 ENSSSCT00000007388 ENSSSCT00000007388 . . . . ENSSSCT00000007394 ENSSSCT00000007395 ENSSSCT00000007395 . . . . . . . ENSSSCT00000007406 ENSSSCT00000007405 ENSSSCT00000025586 ENSSSCT00000007409 ENSSSCT00000007412 ENSSSCT00000007412 ENSSSCT00000007412 ENSSSCT00000007413 ENSSSCT00000007413 . . . . . . . . . ENSSSCT00000027506 ENSSSCT00000023214 ENSSSCT00000030532 ENSSSCT00000023214 . . . .

. . . . CHD1L FMO5 PDE4DIP . . . WARS WARS . . . . . . . . . . MAN1A2 MAN1A2 . CD101 CD101 CD101 CD101 CD101 CD101 CD101 CD101 CD101 CD101 IGSF3 . . . . . SLC22A15 SLC22A15 SLC22A15 . . . . TSHB SYCP1 SYCP1 . . . . . . . HIPK1 HIPK1 BCL2L15 BCL2L15 PHTF1 PHTF1 PHTF1 MAGI3 MAGI3 . . . . . . . . . C1orf162 CEPT1 CHIA CEPT1 . . . .

intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intron intron intergenic intron intron intron intron intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intergenic promoter intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic promoter intron intron intron intergenic intergenic intergenic intergenic

0.214 -0.012 -0.123 0.121 -0.025 0.137 . . 0.244 -0.544 0.104 0.05 . 0.081 -0.016 . 0.347 . 0.151 0.252 0.252 0.166 . . -0.091 0.064 0.064 0.064 0.064 -0.19 -0.19 -0.19 0.134 0.134 0.134 0.096 . . -0.043 0.219 0.03 0.921 -0.025 . 0.065 -0.103 -0.034 0.088 0.229 . 1.372 0.9 -0.06 -0.18 0.151 . -0.229 0.463 1.015 1.015 0.258 0.258 . 0.29 0.046 0.167 0.218 0.095 -0.166 0.327 0.035 0.809 0.663 0.145 0.226 0.01 . 0.053 0.053 0.056 0.203 0.145 0.12 0.18

. rs792604029 . rs791556347 . 852898 rs7869 . . rs787094981 rs791364294 . 727858 rs7886 rs790350667 . rs788354726 rs791956016 432920 rs7933 rs793429710 rs787132408 793732 rs7893 793732 rs7893 . 598913 rs7889 rs790733726 . rs793366918 rs793366918 rs793366918 rs793366918 157095 rs7897 157095 rs7897 157095 rs7897 290138 rs7864 290138 rs7864 290138 rs7864 rs793392023 902703 rs7894 928760 rs7874 273282 rs7923 rs791808624 . rs790261029 rs792104710 rs786717998 rs789969639 865818 rs7869 rs791516972 624855 rs7884 rs786823137 rs787802898 977704 rs7918 . . . 349317 rs7869 rs792850401 rs792370991 rs791940826 260982 rs7893 260982 rs7893 rs789573201 rs789573201 rs788860196 rs791356597 . rs791237278 rs790320346 rs793354030 rs786859939 825417 rs7938 rs792837597 rs786238574 rs791581826 rs791742631 483575 rs7885 rs789573532 155500 rs7871 895404 rs7913 895404 rs7913 rs786413265 rs787689226 rs790924087 . rs790475222

3 2 2 2 4 2 3 4 2 2 3 2 2 3 2 3 5 2 3 2 2 2 3 2 2 2 2 2 2 4 4 4 2 2 2 2 3 2 2 2 2 2 2 2 3 2 2 3 2 2 2 2 2 2 3 2 2 2 4 4 2 2 2 2 3 2 2 2 2 2 2 2 4 3 2 2 2 2 2 2 2 2 2 2

AAAC.GTTT ACC.GGT AAGAG.CTCTT AC.GT AAAG.CTTT AT.AT AC.GT AT.AT AT.AT AGG.CCT AGG.CCT AT.AT ATC.GAT AC.GT AAT.ATT AAT.ATT AAT.ATT AAT.ATT AAT.ATT AAT.ATT AAT.ATT ATC.GAT ATC.GAT ATC.GAT ATC.GAT ATC.GAT ATC.GAT ATC.GAT AC.GT AC.GT AAAT.ATTT AAAT.ATTT AG.CT AG.CT AAT.ATT AG.CT AAAAC.GTTTT AC.GT ATC.GAT AT.AT AT.AT ACAT.ATGT AT.AT AG.CT AAAAC.GTTTT AT.AT AT.AT AAC.GTT AAAAC.GTTTT AAAG.CTTT AC.GT AAG.CTT ACAG.CTGT AAAAG.CTTTT AAAG.CTTT AAAAG.CTTTT AAAC.GTTT AAAT.ATTT AAC.GTT AC.GT AAAC.GTTT AAAGC.GCTTT AT.AT AG.CT AT.AT AAAG.CTTT AATG.CATT AAAAG.CTTTT AC.GT AAAAC.GTTTT AT.AT AG.CT AT.AT AC.GT AC.GT AG.CT AACC.GGTT AC.GT AT.AT AAAAT.ATTTT AAAAAT.ATTTTT AAAAC.GTTTT AC.GT AC.GT

4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4

120245327 120302917 120536659 120690195 121371120 121413228 121600850 121703953 121703953 121828012 121828012 122394762 122398413 122772893 123129877 123129877 123129877 123129877 123129877 123129877 123129877 123139761 123139761 123139761 123139761 123139761 123139761 123139761 123248841 123285234 123300078 123436784 123860254 123922438 123931195 123982463 124386483 124393654 124403401 124445590 124453163 124480905 124608726 124729209 125014090 125124854 125128680 125682621 125742661 125845586 125875672 125887150 125892356 125960206 126109574 126149369 126765524 126919186 127064948 127074650 127301975 127512443 127521827 127574506 127593303 127763731 127903248 128371270 128570590 128667009 128764331 128923517 128998403 129044693 129044693 129168525 129312520 129410841 129444234 129604115 129722191 129725395 129738796 129983528

120245345 120302933 120536702 120690209 121371148 121413237 121600869 121703964 121703964 121828030 121828030 122394773 122398426 122772909 123129891 123129891 123129891 123129891 123129891 123129891 123129891 123139776 123139776 123139776 123139776 123139776 123139776 123139776 123248862 123285259 123300096 123436802 123860265 123922450 123931206 123982474 124386505 124393665 124403415 124445599 124453172 124480933 124608739 124729219 125014108 125124867 125128689 125682634 125742677 125845608 125875689 125887161 125892370 125960229 126109585 126149385 126765547 126919208 127064973 127074676 127301993 127512464 127521839 127574515 127593325 127763748 127903263 128371291 128570603 128667031 128764354 128923526 128998413 129044703 129044703 129168534 129312537 129410851 129444243 129604137 129722226 129725419 129738806 129983537

4.75 5.66667 8.8 7.5 7.25 5 10 6 6 6.33333 6.33333 6 4.66667 8.5 5 5 5 5 5 5 5 5.33333 5.33333 5.33333 5.33333 5.33333 5.33333 5.33333 11 13 4.75 4.75 6 6.5 4 6 4.6 6 5 5 5 7.25 7 5.5 3.8 7 5 4.66667 3.4 5.75 9 4 3.75 4.8 3 3.4 6 5.75 8.66667 13.5 4.75 4.4 6.5 5 11.5 4.5 4 4.4 7 4.6 12 5 5.5 5.5 5.5 5 4.5 5.5 5 4.6 6 5 5.5 5

. ENSSSCT00000007459 ENSSSCT00000007463 . . ENSSSCT00000007487 ENSSSCT00000023502 ENSSSCT00000025132 ENSSSCT00000007493 ENSSSCT00000007495 ENSSSCT00000007496 . . ENSSSCT00000007504 ENSSSCT00000035715 ENSSSCT00000034022 ENSSSCT00000033143 ENSSSCT00000022367 ENSSSCT00000007505 ENSSSCT00000033782 ENSSSCT00000035789 ENSSSCT00000035789 ENSSSCT00000035715 ENSSSCT00000033143 ENSSSCT00000022367 ENSSSCT00000007505 ENSSSCT00000033782 ENSSSCT00000034022 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000007510 . . . . . . . . . . ENSSSCT00000007513 . ENSSSCT00000007515 ENSSSCT00000035678 . ENSSSCT00000007517 ENSSSCT00000007517 ENSSSCT00000007517 ENSSSCT00000007520 . ENSSSCT00000007524 ENSSSCT00000007524 ENSSSCT00000007528

. . . . . KIAA1324 . AKNAD1 AKNAD1 FNDC7 FNDC7 . . . NTNG1 NTNG1 NTNG1 NTNG1 NTNG1 NTNG1 NTNG1 NTNG1 NTNG1 NTNG1 NTNG1 NTNG1 NTNG1 NTNG1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . COL11A1 . . . . . . . . . . SLC30A7 . VCAM1 VCAM1 . CDC14A CDC14A CDC14A . . SLC35A3 SLC35A3 PALMD

intergenic intron intron intergenic intergenic intron intron intron intron promoter promoter intergenic intergenic intron intron intron intron intron intron intron intron intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intron intron intergenic intron intron intron intron intergenic intron intron intron

. -0.074 -0.128 . 0.103 0.144 . . . . . 0.158 0.17 0.55 0.087 0.087 0.087 0.087 0.087 0.087 0.087 0.088 0.088 0.088 0.088 0.088 0.088 0.088 -0.452 0.144 0 . -0.086 0.19 0.128 -0.204 -0.229 . -0.124 . . 0.039 . -0.176 0.073 . 0.098 -0.02 0.099 . -0.145 . . . . -0.142 0.067 0.046 0.375 . 0.474 -0.106 -0.012 -0.146 0.046 . 0.023 . . -0.098 . -0.456 . 0.804 0.804 -0.049 0.054 0.12 . 0.042 . 4.582 0.143 0.116

. rs788288646 418612 rs7877 rs786726796 rs790639693 rs790815005 . . . rs790816646 rs790816646 rs701312758 rs793572984 . rs791341256 rs791341256 rs791341256 rs791341256 rs791341256 rs791341256 rs791341256 537629 rs7901 537629 rs7901 537629 rs7901 537629 rs7901 537629 rs7901 537629 rs7901 537629 rs7901 rs696498154 rs791295508 778423 rs7876 rs793588911 224749 rs7879 . rs787949499 325621 rs7863 371729 rs7866 059380 rs7864 506799 rs7894 464434 rs7916 . 735249 rs7904 rs786339736 151535 rs7080 761045 rs7930 494543 rs7892 990707 rs7912 469505 rs7916 202608 rs7883 rs790346002 513708 rs7936 rs787827179 . 637565 rs7876 354669 rs7906 . 698541 rs7875 340399 rs7932 885035 rs7909 rs791419708 078262 rs7899 rs787128110 rs789407194 995846 rs7871 . rs788081734 rs791125815 . rs787314544 550777 rs7884 rs793469330 . rs787561075 rs790763321 rs790763321 . rs791951324 rs792765693 rs786387942 879447 rs7869 rs793644086 rs793091476 593654 rs7936 .

3 2 2 7 2 2 2 4 4 2 2 2 2 2 4 4 4 4 4 4 4 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 4 2 2 3 4 2 2 4 2 2 2 2 2 2 2 2 2 2 2 3 4 2 2 4 2 2 2 2 2 2 2 2 2 2 3 3 3 2 2 2 2 2 2 3 2

AT.AT AAAC.GTTT AG.CT AAAATT.AATTTT AAC.GTT AC.GT AT.AT AC.GT AC.GT AAT.ATT AG.CT AT.AT ACAT.ATGT AAAT.ATTT AC.GT AC.GT AAT.ATT AAAC.GTTT AAAG.CTTT AC.GT AAAG.CTTT AT.AT AAAT.ATTT AAAAC.GTTTT AC.GT AAAAT.ATTTT AG.CT AAAT.ATTT AC.GT AAT.ATT AT.AT AAT.ATT AAC.GTT AGGGC.GCCCT AC.GT AC.GT AAC.GTT AATG.CATT AG.CT AG.CT AAAAT.ATTTT AAC.GTT AG.CT AAAC.GTTT AC.GT AAAAT.ATTTT AAAT.ATTT AAAG.CTTT AC.GT AT.AT AAAC.GTTT AAAAC.GTTTT AAAC.GTTT AAT.ATT AAAAG.CTTTT ACAG.CTGT AAAC.GTTT AAAT.ATTT AAAT.ATTT AAT.ATT AT.AT AG.CT AG.CT AAAAC.GTTTT AAAAC.GTTTT AAAAC.GTTTT AAAAC.GTTTT AAAAC.GTTTT AGG.CCT AAAC.GTTT AAAC.GTTT AT.AT AC.GT AG.CT AAT.ATT AAAAC.GTTTT AG.CT AT.AT AC.GT AG.CT AAAC.GTTT AC.GT AT.AT AAAT.ATTT

4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4

130027608 130168903 130183274 130188619 130219709 130385433 130494681 130535910 130754502 130760027 130835919 130915187 130933174 131162248 131522045 132012555 132038462 132086104 132122520 132170872 132177930 132182652 132269953 132278668 132434332 132466428 132644460 132907639 132962088 132993380 133051125 133271245 133380522 133608154 133845545 133867953 133930145 134164544 134249868 134249868 134311514 134333979 134349247 134374546 134402197 134593550 134625335 134762571 134809903 134810964 134869375 134965684 135022535 135023629 135579947 135587270 135601200 135718940 135718940 135759024 135805841 136679253 136754594 136885873 136885873 136885873 136885873 136885873 137168365 137234497 137273023 137574337 137691536 137792343 138158472 138162885 138315919 138418005 138435749 138647678 139096049 139272891 139307839 139484153

130027619 130168915 130183286 130188640 130219725 130385446 130494693 130535922 130754523 130760044 130835928 130915197 130933200 131162279 131522054 132012568 132038481 132086122 132122533 132170897 132177953 132182662 132269968 132278696 132434350 132466456 132644470 132907658 132962118 132993403 133051136 133271257 133380540 133608174 133845555 133867976 133930159 134164559 134249878 134249878 134311528 134333994 134349256 134374559 134402210 134593582 134625353 134762587 134809915 134810974 134869395 134965702 135022554 135023642 135579962 135587289 135601214 135718965 135718965 135759051 135805851 136679265 136754606 136885892 136885892 136885892 136885892 136885892 137168382 137234523 137273034 137574348 137691546 137792375 138158493 138162904 138315940 138418017 138435759 138647690 139096072 139272901 139307849 139484171

6 3.25 6.5 3.66667 5.66667 7 6.5 6.5 11 6 5 5.5 6.75 8 5 7 6.66667 4.75 3.5 13 6 5.5 4 5.8 9.5 5.8 5.5 5 15.5 8 6 4.33333 6.33333 4.2 5.5 12 5 4 5.5 5.5 3 5.33333 5 3.5 7 6.6 4.75 4.25 6.5 5.5 5.25 3.8 5 4.66667 3.2 5 3.75 6.5 6.5 9.33333 5.5 6.5 6.5 4 4 4 4 4 6 6.75 3 6 5.5 16.5 7.33333 4 11 6.5 5.5 6.5 6 5.5 5.5 4.75

. . . . . . . . . . ENSSSCT00000007531 . . . . ENSSSCT00000007532 ENSSSCT00000007532 ENSSSCT00000007532 ENSSSCT00000007532 ENSSSCT00000007532 ENSSSCT00000007532 ENSSSCT00000007532 ENSSSCT00000007532 ENSSSCT00000007532 ENSSSCT00000007532 ENSSSCT00000007532 . . . . . . . . . . . ENSSSCT00000007539 ENSSSCT00000031017 ENSSSCT00000007541 . . . ENSSSCT00000007542 ENSSSCT00000028417 . . ENSSSCT00000007543 . . ENSSSCT00000007545 ENSSSCT00000007545 ENSSSCT00000007546 ENSSSCT00000007546 ENSSSCT00000007551 . ENSSSCT00000007552 ENSSSCT00000007553 ENSSSCT00000034081 . . ENSSSCT00000033701 ENSSSCT00000033701 ENSSSCT00000007569 ENSSSCT00000035989 ENSSSCT00000036583 ENSSSCT00000033701 ENSSSCT00000034411 ENSSSCT00000007570 . . . . . . . . . . . . . . .

. . . . . . . . . . . . . . . DPYD DPYD DPYD DPYD DPYD DPYD DPYD DPYD DPYD DPYD DPYD . . . . . . . . . . . ALG14 . CNN3 . . . . . . . . . . ABCA4 ABCA4 GCLM GCLM TMED5 . . MTF2 MTF2 . . TGFBR3 TGFBR3 TGFBR3 TGFBR3 TGFBR3 TGFBR3 TGFBR3 HFM1 . . . . . . . . . . . . . . .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intron intron intron intron intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intron intron intergenic intergenic intron intergenic intergenic intron intron intron intron intron intergenic intron intron intron intergenic intergenic intron intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

0.077 0.185 0.075 . . -0.026 0.075 0.112 -0.028 . 0.446 . 0.036 . 0.068 0.146 -0.067 -0.039 0.079 -0.036 -0.171 3.53 0.029 -0.269 0.101 0.432 0.348 -0.147 0.039 0.131 0.011 0.1 -0.051 0.05 0.136 -0.086 . 0.099 1.769 1.769 -0.058 0.052 0.056 . . 0.258 0.03 1.165 0.153 0.338 0.117 0.218 0.253 0.241 . . . 0.167 0.167 0.38 0.614 0.251 1.392 0.252 0.252 0.252 0.252 0.252 0.126 0.188 0.118 . 0.373 0.14 0.263 . . . 0.314 . 0.028 -0.21 . .

. 617376 rs7900 rs790163231 rs790583651 906207 rs7934 . rs788663421 rs790103133 rs793420662 . rs791168680 002868 rs7879 rs787920757 rs793094458 rs793044957 rs788560613 267249 rs7887 rs793527285 . rs696178186 rs790768312 . 523991 rs7900 rs791700588 rs792819384 rs707676537 rs793856650 rs792788420 rs790861084 175644 rs7864 rs791507688 315226 rs7909 rs788645404 . rs786477494 rs708535863 rs788471019 . rs786622356 rs786622356 rs789238456 rs792580625 . rs789128113 rs786562571 rs789551788 354776 rs7901 037502 rs7864 rs793349084 rs789909014 rs788916555 rs788276046 rs792689974 rs793129780 rs790765239 . rs792335977 rs789674928 rs789674928 228315 rs7883 rs787903374 rs792716239 rs792273460 rs790274523 rs790274523 rs790274523 rs790274523 rs790274523 494219 rs7887 . 749940 rs7895 rs789660025 . rs789982832 rs786704468 rs786407454 . 805310 rs7888 . rs788274045 rs789996241 rs793560151 007328 rs7926 rs787103557

2 2 3 3 4 4 2 2 2 2 2 2 2 2 4 2 2 3 2 2 2 3 2 2 2 2 2 2 3 3 2 3 2 2 2 2 2 3 3 3 2 2 3 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 4 3 2 2 2 3 2 2

AAAC.GTTT AAAAC.GTTTT AAG.CTT AAATT.AATTT AG.CT AAAAC.GTTTT AC.GT AG.CT AAC.GTT AAAG.CTTT AAAC.GTTT AC.GT AG.CT AAAG.CTTT AG.CT AGG.CCT AT.AT AAAAAC.GTTTTT AG.CT AC.GT AAAC.GTTT AAG.CTT AC.GT AG.CT ATC.GAT AAT.ATT AAAC.GTTT AAC.GTT AAC.GTT AAAT.ATTT AAAC.GTTT AGG.CCT AAAC.GTTT AT.AT AATG.CATT AAAT.ATTT AAAT.ATTT AGG.CCT AGC.GCT AAAC.GTTT ACCCC.GGGGT AAAT.ATTT AC.GT AAAAAC.GTTTTT AC.GT AG.CT AAAC.GTTT AC.GT AAAC.GTTT AAAT.ATTT AATC.GATT AATC.GATT AAAC.GTTT AAC.GTT AAGG.CCTT AC.GT AATG.CATT AGAT.ATCT AAAT.ATTT AAAC.GTTT AGAT.ATCT AAAAC.GTTTT AAAAAG.CTTTTT AAAAC.GTTTT AG.CT AT.AT AAAAC.GTTTT AAAAC.GTTTT AATG.CATT AG.CT AG.CT AC.GT AC.GT AAT.ATT AC.GT AAT.ATT AAAT.ATTT AC.GT AAC.GTT AG.CT ACC.GGT AT.AT AAC.GTT AAAC.GTTT

4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5

139610163 139738145 139793449 140193692 141203828 141298092 141347773 141406932 141470107 141728671 141957226 142145143 142180379 142418861 142448831 142643470 142748854 142759611 1529171 1852971 2014771 2556673 2596719 2937784 4161504 4311716 4317773 4615805 4615805 4683576 4817125 4851668 5096381 5105386 5153012 5229962 5229962 5368637 5374983 5376116 5380221 5544371 5557370 5557816 6020251 6291504 6310628 6504134 6678567 6700767 7017545 7017545 7791700 7836333 8393382 8505212 8536292 8800627 9056157 9354800 9407324 10591248 10595119 10605387 10681154 10740662 11002822 11595663 11665964 12205469 12280669 12555925 12688682 12796399 12863319 12882175 12927310 12988389 13174933 13458979 13473533 13491901 13567619 13578181

139610194 139738163 139793465 140193714 141203837 141298109 141347790 141406944 141470123 141728701 141957244 142145161 142180389 142418873 142448846 142643481 142748866 142759629 1529182 1852984 2014790 2556695 2596731 2937794 4161518 4311732 4317791 4615824 4615824 4683588 4817143 4851680 5096406 5105397 5153030 5229978 5229978 5368651 5375000 5376142 5380237 5544387 5557381 5557838 6020261 6291517 6310644 6504164 6678579 6700778 7017576 7017576 7791718 7836352 8393395 8505221 8536318 8800638 9056183 9354817 9407338 10591278 10595137 10605405 10681165 10740673 11002841 11595687 11665983 12205480 12280681 12555937 12688694 12796415 12863329 12882216 12927323 12988399 13174946 13458991 13473546 13491919 13567630 13578199

8 3.8 5.66667 4.6 5 3.6 9 6.5 5.66667 7.75 4.75 9.5 5.5 3.25 8 4 6.5 3.16667 6 7 5 7.66667 6.5 5.5 5 5.66667 4.75 6.66667 6.66667 3.25 4.75 4.33333 6.5 6 4.75 4.25 4.25 5 6 6.75 3.4 4.25 6 3.83333 5.5 7 4.25 15.5 3.25 3 8 8 4.75 6.66667 3.5 5 6.75 3 6.75 4.5 3.75 6.2 3.16667 3.8 6 6 4 5 5 6 6.5 6.5 6.5 5.66667 5.5 14 3.5 5.5 4.66667 6.5 4.66667 9.5 4 4.75

. . . . . . ENSSSCT00000007590 . . ENSSSCT00000028257 . ENSSSCT00000007595 . . . . ENSSSCT00000007603 ENSSSCT00000007603 . . . . ENSSSCT00000000029 . . ENSSSCT00000000066 ENSSSCT00000000066 ENSSSCT00000026332 ENSSSCT00000000074 . ENSSSCT00000000078 . . . . ENSSSCT00000000082 ENSSSCT00000031184 ENSSSCT00000000084 ENSSSCT00000000084 ENSSSCT00000000084 ENSSSCT00000000084 . . . . . . . . . ENSSSCT00000022302 ENSSSCT00000000116 . . . . . . . . ENSSSCT00000024278 . . . . . . . ENSSSCT00000028759 . ENSSSCT00000000162 ENSSSCT00000000171 ENSSSCT00000000171 ENSSSCT00000000171 ENSSSCT00000000171 ENSSSCT00000000171 . . ENSSSCT00000000173 ENSSSCT00000000177 ENSSSCT00000000177 ENSSSCT00000000177 . .

. . . . . . LMO4 . . . . CLCA1 . . . . ZNHIT6 ZNHIT6 . . . . EFCAB6 . . DESI1 DESI1 EP300 EP300 . SLC25A17 . . . . SGSM3 SGSM3 . . . . . . . . . . . . . PLA2G6 PLA2G6 . . . . . . . . . . . . . . . . . . SYN3 BTBD11 BTBD11 BTBD11 BTBD11 BTBD11 . . CRY1 RFX4 RFX4 RFX4 . .

intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intron intergenic intron intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intron intergenic intergenic intron intron intron intron intergenic intron intergenic intergenic intergenic intergenic intron intron intron cds intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intron intron intron intron intron intron intergenic intergenic intron intron intron intron intergenic intergenic

. 0.777 . . 0.046 0.252 3.653 1.665 -0.113 0.061 0.19 0.599 0.173 0.411 0.026 0.152 1.534 . 0.062 -0.039 -0.178 0.033 -0.078 -0.119 -0.03 0.184 0.076 . . . 0.175 0.289 . 0.673 0.087 . . 0.101 0.281 -0.09 0.21 . 0.193 0.169 0.164 . . -0.136 . 0.144 . . . . -0.091 -0.285 -0.038 0.135 . -0.158 0.199 0.15 0.072 0.041 -0.115 . . -0.242 -0.062 0.08 -0.065 0.045 -0.058 -0.004 0.139 . . -0.045 . 0.071 0.215 . 0.063 0.015

189979 rs7933 rs786876175 551456 rs7885 rs793015156 589896 rs7893 297848 rs7874 rs786545600 rs789009050 866755 rs7917 rs786851127 rs793452112 430116 rs7885 . . rs788579170 . rs709165712 295164 rs7914 . rs792433403 rs792128714 465032 rs7883 887812 rs7884 rs786540436 904185 rs7922 593571 rs7925 rs791267180 255902 rs7872 255902 rs7872 rs792758549 rs791539431 rs791068223 rs791327969 rs790221783 rs787709638 955580 rs7890 955580 rs7890 rs695920451 319057 rs7865 rs792472842 298535 rs7906 rs790685073 rs790975584 rs789279659 rs790179919 556789 rs7931 rs790742556 . rs788590946 rs787561508 rs786564139 rs786564139 . rs786693844 959885 rs7864 . 908912 rs7915 rs787425775 087194 rs7882 rs789645502 rs786553023 . rs788666177 rs788001243 rs787493435 694622 rs7932 rs793622268 rs790068249 . rs789112376 . 230295 rs7882 . rs789757747 rs791039369 rs792254425 . . 348907 rs7908 rs790941400 579284 rs7933 rs790435213 985995 rs7922 rs789481293

4 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 4 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 4 2 2 2 3 3 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 3 3 2 2 2 2 2 2 2 2 2 2 2

AG.CT AG.CT ACAT.ATGT AAAG.CTTT AC.GT AG.CT AG.CT AT.AT AC.GT AAAT.ATTT AATG.CATT AC.GT AC.GT AAAC.GTTT AAAC.GTTT AG.CT AAC.GTT AAAAC.GTTTT AAAAC.GTTTT AAAAAG.CTTTTT AAAC.GTTT AAT.ATT AC.GT AAAC.GTTT AAAAAG.CTTTTT AAG.CTT AAG.CTT AAT.ATT AAAC.GTTT AC.GT AC.GT AC.GT AC.GT AAAC.GTTT AAAC.GTTT ACAT.ATGT AAAG.CTTT AAAAC.GTTTT AAAC.GTTT AAAAC.GTTTT AC.GT AAAAAC.GTTTTT AC.GT AC.GT AG.CT AC.GT AT.AT AT.AT AAAAT.ATTTT AAAC.GTTT AAAC.GTTT AAT.ATT AG.CT AAAC.GTTT AG.CT AAAAC.GTTTT AAAAT.ATTTT AC.GT AAT.ATT AC.GT AG.CT AAAT.ATTT AT.AT AAAG.CTTT AT.AT AAAC.GTTT AT.AT AT.AT AAAC.GTTT AAAAC.GTTTT AAAT.ATTT AAAC.GTTT AAG.CTT AT.AT AAAT.ATTT AC.GT AT.AT AAAAG.CTTTT AGG.CCT AAAAC.GTTTT AC.GT AC.GT AG.CT AT.AT

5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5

13581747 14116797 14141808 14211324 14355221 14510301 14828609 14836350 15177959 15363580 15622236 15849304 15955788 16187602 16556625 16580799 16786055 17128691 17163086 17541169 17570945 18445460 18582059 18765703 19073340 19180373 19180373 19302109 19579071 20459451 20459451 20459451 20459451 20492473 20706177 20807336 21291321 22040301 22403097 22740935 22811643 23428609 23610219 23610219 24138141 24511712 24835363 24835363 24919631 24920565 24974090 25098125 25152606 25194540 25206296 25216496 25608249 25974711 26576384 26584159 26649914 26879663 26973839 27000988 27056008 27172276 27279805 27292936 27303885 27477660 27826224 27894546 27924137 28159730 28238832 28507676 28537658 28882558 29044428 29210231 29853024 30183337 30238992 30398998

13581759 14116807 14141826 14211335 14355233 14510312 14828618 14836359 15177968 15363597 15622274 15849319 15955806 16187627 16556649 16580812 16786069 17128707 17163109 17541190 17570967 18445482 18582069 18765729 19073366 19180397 19180397 19302122 19579089 20459463 20459463 20459463 20459463 20492505 20706189 20807351 21291340 22040315 22403119 22740954 22811661 23428638 23610239 23610239 24138153 24511726 24835373 24835373 24919646 24920583 24974104 25098140 25152619 25194554 25206308 25216510 25608268 25974734 26576402 26584180 26649933 26879680 26973848 27001007 27056025 27172290 27279814 27292945 27303908 27477681 27826238 27894558 27924152 28159743 28238854 28507688 28537676 28882580 29044446 29210257 29853038 30183363 30239005 30399009

6.5 5.5 4.75 3 6.5 6 5 5 5 4.5 9.75 8 9.5 6.5 6.25 7 5 3.4 4.8 3.66667 5.75 7.66667 5.5 6.75 4.5 8.33333 8.33333 4.66667 4.75 6.5 6.5 6.5 6.5 8.25 3.25 4 5 3 5.75 4 9.5 5 10.5 10.5 6.5 7.5 5.5 5.5 3.2 4.75 3.75 5.33333 7 3.75 6.5 3 4 12 6.33333 11 10 4.5 5 5 9 3.75 5 5 6 4.4 3.75 3.25 5.33333 7 5.75 6.5 9.5 4.6 6.33333 5.4 7.5 13.5 7 6

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000000185 CACNB3 intron ENSSSCT00000000188 CCDC65 intron . . intergenic . . intergenic ENSSSCT00000000212 SPATS2 intron . . intergenic ENSSSCT00000022818 . intron . . intergenic . . intergenic ENSSSCT00000028346 DIP2B intron ENSSSCT00000028346 DIP2B intron . . intergenic ENSSSCT00000000245 SCN8A intron ENSSSCT00000000269 KRT2 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000000299 . intron ENSSSCT00000023450 . intron . . intergenic . . intergenic ENSSSCT00000035821 ITGA5 intron ENSSSCT00000034427 ITGA5 intron ENSSSCT00000000314 ITGA5 intron ENSSSCT00000033141 ITGA5 promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000000393 DGKA promoter ENSSSCT00000000434 RBMS2 intron ENSSSCT00000032195 BAZ2A 3'utr ENSSSCT00000000436 BAZ2A 3'utr ENSSSCT00000028141 . intron ENSSSCT00000027063 . intron ENSSSCT00000000478 GLI1 3'utr ENSSSCT00000000472 . 3'utr . . intergenic . . intergenic ENSSSCT00000000489 XRCC6BP1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000029741 . intron . . intergenic . . intergenic

-0.144 -0.042 0.245 0.113 -0.152 -0.507 -0.225 . 1.164 . . . . . 0.629 0.308 -0.078 -0.019 . 0.195 0.109 -0.049 -0.093 0.108 . -0.054 -0.054 0.29 . -0.092 -0.092 -0.092 -0.092 . . -0.147 . . . 0.372 0.522 . 1.282 1.282 -0.661 0.263 . . 0.335 0.269 0.067 -0.041 0.041 0.064 0.42 . 0.119 . 0.162 0.11 . . . -0.14 0.336 . . . 0.3 . -0.051 0.499 0.125 . 0.056 . . . -0.036 0.037 0.222 1.026 -0.034 0.126

rs699432491 . rs786742196 . rs791814139 rs788765438 rs792213669 rs692763202 rs788831760 rs791667725 rs793599376 824486 rs7888 . . rs790451643 913039 rs7924 959644 rs7893 953759 rs7930 . rs792760808 rs791306152 219071 rs7871 . rs787265951 579749 rs7866 001145 rs7877 001145 rs7877 rs787057857 rs792919399 140258 rs7864 140258 rs7864 140258 rs7864 140258 rs7864 rs789830913 . . 357841 rs7891 . 587560 rs7901 rs793005507 . rs786286424 . . . . rs788073903 rs788073903 . rs790219891 . . 776649 rs7885 . rs787223154 . 610540 rs7891 369835 rs7091 rs791275580 . 595878 rs7918 rs787574936 458904 rs7880 rs787790445 . rs789879738 rs791039313 rs792362689 673994 rs7937 991081 rs7916 rs701609808 rs789225067 rs787302028 952197 rs7912 rs790124948 . 989885 rs7864 rs793420915 rs789989604 485295 rs7926 rs793567246 . 402319 rs7886 686751 rs7931

2 2 2 2 2 2 2 2 2 2 2 3 2 3 2 2 2 2 2 2 2 2 2 2 2 3 3 2 2 3 3 3 3 2 2 4 2 2 2 2 2 2 2 2 2 3 2 2 3 2 3 2 2 3 2 2 2 4 2 2 2 2 3 2 4 2 2 2 2 2 3 2 4 2 2 2 3 2 3 2 2 2 2 2

AT.AT AAC.GTT AAC.GTT AAAT.ATTT AAAT.ATTT AAAC.GTTT AAAAC.GTTTT AAC.GTT AAAC.GTTT AC.GT AC.GT AAC.GTT AC.GT AAG.CTT AC.GT AG.CT AAC.GTT AAAAC.GTTTT AAAC.GTTT AG.CT AAAC.GTTT ACTC.GAGT AAAAC.GTTTT AG.CT AAT.ATT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AAAAG.CTTTT AAAT.ATTT AC.GT AAAC.GTTT AC.GT ACTCTC.GAGAG AC.GT AC.GT AT.AT AC.GT AC.GT AC.GT AC.GT AAAC.GTTT AT.AT AAAG.CTTT AAG.CTT AC.GT AAAAAC.GTTTTT AAAAC.GTTTT AC.GT AG.CT AAAC.GTTT AAC.GTT AT.AT AATG.CATT AG.CT AGAT.ATCT AAAT.ATTT ACAT.ATGT AAT.ATT AC.GT AT.AT AC.GT AT.AT AAAAT.ATTTT AAAAT.ATTTT AATC.GATT AC.GT AAAAAC.GTTTTT AAC.GTT AC.GT AAC.GTT AC.GT AAT.ATT AAG.CTT AAC.GTT AAAC.GTTT AAAAT.ATTTT AC.GT AAT.ATT AT.AT AAAG.CTTT AT.AT AAAC.GTTT AAAGG.CCTTT

5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5

31298702 31401697 31431410 31462571 31561893 31588670 31715933 31766269 32221677 32678916 32786347 33009949 33036152 33057948 33171312 33228316 33274093 33276883 33391263 33406060 33936717 34211027 34243841 34298935 34389577 34412269 34522475 34573928 34601439 34833325 34862561 35180908 35364312 35540348 35810285 35962335 36113275 36182189 36182189 36182189 36601044 36686334 36965115 37057701 37184310 37191693 37233830 37275617 37405659 37493335 37655578 37747133 37767936 37852000 37901119 38069714 38357105 38359551 38476956 38599574 38612650 38695065 39099742 39147598 39160393 39271011 39288339 39333482 39371033 39490521 39506558 39515548 39603525 39610349 39699372 40139752 40302898 40321169 40336325 40355074 40785121 40897041 41432611 41433301

31298720 31401717 31431426 31462593 31561906 31588694 31715958 31766280 32221691 32678930 32786367 33009965 33036165 33057962 33171326 33228325 33274106 33276897 33391279 33406070 33936730 34211046 34243859 34298946 34389589 34412291 34522492 34573950 34601470 34833352 34862571 35180932 35364322 35540370 35810302 35962345 36113286 36182200 36182200 36182200 36601053 36686351 36965124 37057712 37184323 37191704 37233853 37275631 37405669 37493356 37655592 37747155 37767946 37852019 37901133 38069750 38357126 38359566 38476972 38599585 38612669 38695084 39099753 39147622 39160417 39271029 39288350 39333506 39371052 39490537 39506579 39515565 39603536 39610361 39699391 40139767 40302923 40321190 40336336 40355083 40785135 40897051 41432629 41433318

9.5 7 5.66667 5.75 3.5 6.25 5.2 4 3.75 7.5 10.5 5.66667 7 5 7.5 5 4.66667 3 4.25 5.5 3.5 5 3.8 6 4.33333 5.75 4.5 4.6 6.4 7 5.5 6.25 5.5 3.83333 9 5.5 6 6 6 6 5 4.5 5 3 4.66667 6 4 3 5.5 11 3.75 7.66667 5.5 5 7.5 9.25 5.5 4 5.66667 6 10 10 6 5 5 4.75 6 4.16667 6.66667 8.5 7.33333 9 4 4.33333 6.66667 4 5.2 11 4 5 3.75 5.5 4.75 3.6

. . ENSSSCT00000020867 . . . . ENSSSCT00000025861 ENSSSCT00000028687 . ENSSSCT00000000507 . ENSSSCT00000028225 ENSSSCT00000028225 . . . . ENSSSCT00000000509 ENSSSCT00000000509 ENSSSCT00000000515 ENSSSCT00000000516 ENSSSCT00000000516 . . . . . . . . . . . ENSSSCT00000000524 ENSSSCT00000000526 . ENSSSCT00000033585 ENSSSCT00000034939 ENSSSCT00000000530 . ENSSSCT00000022623 . . ENSSSCT00000000541 ENSSSCT00000000541 . ENSSSCT00000000543 ENSSSCT00000032079 ENSSSCT00000032079 . . . . . . ENSSSCT00000000548 ENSSSCT00000000548 ENSSSCT00000000550 ENSSSCT00000000551 . ENSSSCT00000000553 ENSSSCT00000000555 ENSSSCT00000000555 ENSSSCT00000000555 ENSSSCT00000000555 ENSSSCT00000000555 ENSSSCT00000000555 ENSSSCT00000000555 ENSSSCT00000000555 ENSSSCT00000000555 ENSSSCT00000000555 . . . . . . . . . . . .

. . U6 . . . . SRGAP1 TBC1D30 . LEMD3 . MSRB3 MSRB3 . . . . HMGA2 HMGA2 HELB GRIP1 GRIP1 . . . . . . . . . . . . MDM2 . LYZ LYZ LYZ . . . . CNOT2 CNOT2 . PTPRB PTPRR PTPRR . . . . . . . . RAB21 TBC1D15 . TPH2 TRH-DE TRH-DE TRH-DE TRH-DE TRH-DE TRH-DE TRH-DE TRH-DE TRH-DE TRH-DE . . . . . . . . . . . .

intergenic intergenic promoter intergenic intergenic intergenic intergenic intron intron intergenic intron intergenic intron intron intergenic intergenic intergenic intergenic intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intron intron intron intergenic intron intergenic intergenic intron intron intergenic intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intergenic intron intron intron intron intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

0.014 -0.11 . . 0.235 0.068 0.055 0.588 0.147 0.081 0.427 0.291 0.124 -0.009 0.133 0.052 . . . 0.708 -0.066 0.055 -0.071 0.061 -0.281 0.051 -0.074 0.208 0.184 0.045 0.379 -0.078 0.038 . 0.229 . 0.336 -0.106 -0.106 -0.106 0.07 . -0.01 0.31 0.204 2.23 1.936 0.267 0.08 . 0.149 -0.064 -0.279 0.023 . . -0.01 0.217 0.303 0.134 -0.048 0.644 0.45 . 0.096 0.28 0.048 -0.04 0.192 0.142 . . 0.085 . . -0.189 . -0.009 0.061 . 0.118 0.096 -0.041 0.031

rs790241021 772776 rs7923 rs792485779 rs788870371 . 699642 rs7902 rs787035574 rs789041469 rs786770777 rs791671598 . rs789549514 155300 rs7927 . rs790427726 . rs789529167 rs787016193 687815 rs7902 . 619442 rs7867 rs789141965 rs787356599 125816 rs7903 rs696456646 rs789370231 rs789436456 . 096042 rs7918 rs711492149 366950 rs7890 . rs786896987 . rs793585266 rs788012636 rs788075889 . . . 668764 rs7933 rs791374272 . . rs793084428 809398 rs7906 341253 rs7901 . 894799 rs7918 011453 rs6989 rs790948225 rs789047498 rs791041653 rs787818634 019093 rs7901 rs787713533 952081 rs7882 109111 rs7902 . . rs790448401 rs792164470 787906 rs7931 546637 rs7881 291485 rs7905 rs787600447 rs787442755 rs787954421 . rs792906584 rs788671838 rs790648064 . rs790195309 792332 rs7875 rs790442389 472994 rs7902 115590 rs7915 rs789673277 rs787076393 . . 289135 rs7870 319818 rs7924

2 2 2 2 2 2 2 2 2 3 5 3 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 3 3 3 3 3 2 2 2 3 3 2 2 3 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 4 2 2 2 6 2 2 3 2 2 3 2 2 2 2 2 2

AAAC.GTTT AC.GT AAAC.GTTT AAT.ATT AT.AT AG.CT AT.AT AAACT.AGTTT AT.AT AG.CT AAAT.ATTT AAAAC.GTTTT AAAT.ATTT ACAT.ATGT AAAC.GTTT AAAT.ATTT AAC.GTT AAAC.GTTT AT.AT AAAT.ATTT AAAT.ATTT AACC.GGTT AAT.ATT AAT.ATT AAT.ATT AAAG.CTTT AG.CT AT.AT AAAAAC.GTTTTT AC.GT AAAT.ATTT AT.AT AAAT.ATTT AC.GT AC.GT AT.AT AGGG.CCCT AAC.GTT AC.GT AAAT.ATTT AAC.GTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAC.GTT AAC.GTT AAAC.GTTT AAAC.GTTT AAGG.CCTT AC.GT AG.CT AAAT.ATTT AAG.CTT AG.CT AT.AT AAAAC.GTTTT AC.GT AC.GT AAC.GTT AT.AT AAAG.CTTT AAAT.ATTT AAGT.ACTT AC.GT AAAC.GTTT AAAAAC.GTTTTT AAAC.GTTT AAAC.GTTT AT.AT AAAAC.GTTTT AAAC.GTTT AC.GT AAAAC.GTTTT AAAAC.GTTTT ACAT.ATGT AC.GT AG.CT AAAC.GTTT AT.AT AC.GT AAAC.GTTT AC.GT AAAC.GTTT

5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5

41440160 41664172 41697137 42317040 42378896 42450307 42491107 42695366 42766377 42964334 43032537 43306894 43988807 44073284 44087608 44101615 44541480 44588740 44710359 44763382 44763382 44886260 44932344 44932344 44932344 45536934 46610527 46649857 47129181 47171854 47422864 47548107 47662507 48000562 48242996 48244327 48270418 48538424 48800401 49271054 49444612 49511773 49618912 49618912 49618912 50138288 50384927 50398783 51525324 51631090 51998912 52107206 52253996 52838182 52883414 53205293 53305701 53375479 53718466 53787480 53791359 53844213 53871917 53910190 54101821 54328697 54660455 54777123 54947959 55084616 55170394 55333293 55483396 55695115 55809557 55819066 56114174 56161994 56236402 56479762 56703873 56831159 56968177 56977443

41440182 41664198 41697157 42317054 42378918 42450322 42491117 42695396 42766387 42964355 43032550 43306909 43988820 44073306 44087629 44101637 44541491 44588756 44710370 44763400 44763400 44886284 44932361 44932361 44932361 45536949 46610539 46649867 47129201 47171872 47422887 47548119 47662525 48000574 48243008 48244341 48270445 48538446 48800413 49271075 49444627 49511787 49618937 49618937 49618937 50138309 50384944 50398796 51525342 51631111 51998927 52107221 52254018 52838205 52883432 53205304 53305724 53375493 53718480 53787492 53791368 53844245 53871936 53910201 54101833 54328731 54660477 54777139 54947980 55084626 55170420 55333307 55483406 55695133 55809590 55819096 56114196 56162010 56236417 56479772 56703884 56831176 56968195 56977461

5.75 13.5 5.25 5 11.5 8 5.5 6.2 5.5 11 3.5 3.2 3.5 5.75 5.5 5.75 4 4.25 6 4.75 4.75 6.25 6 6 6 4 6.5 5.5 3.5 9.5 6 6.5 4.75 6.5 6.5 7.5 7 7.66667 6.5 5.5 5.33333 3.75 6.5 6.5 6.5 7.33333 6 3.5 4.75 5.5 8 8 5.75 8 9.5 6 4.8 7.5 7.5 4.33333 5 8.25 5 3 6.5 8.75 3.83333 4.25 5.5 5.5 5.4 3.75 5.5 3.8 6.8 7.75 11.5 8.5 4 5.5 6 4.5 9.5 4.75

. . . . ENSSSCT00000000562 . . . . . . ENSSSCT00000029484 . . . . . ENSSSCT00000000570 . ENSSSCT00000000571 ENSSSCT00000030054 ENSSSCT00000031839 ENSSSCT00000031839 ENSSSCT00000000572 ENSSSCT00000036458 . . . . . ENSSSCT00000028514 ENSSSCT00000000582 ENSSSCT00000000578 . . . . . . . . ENSSSCT00000000588 ENSSSCT00000027008 ENSSSCT00000000592 ENSSSCT00000031448 . ENSSSCT00000031326 ENSSSCT00000031326 ENSSSCT00000000602 . . . ENSSSCT00000025989 . . . . . . . . . . . . . . . . . ENSSSCT00000000621 . . . ENSSSCT00000027940 ENSSSCT00000027940 . . . . . . ENSSSCT00000000632 ENSSSCT00000000632

. . . . KRR1 . . . . . . OSBPL8 . . . . . PKP2 . . . . . FGD4 FGD4 . . . . . . OVCH1 ERGIC2 . . . . . . . . KLHL42 PPFIBP1 PPFIBP1 PPFIBP1 . ASUN ASUN RASSF8 . . . KRAS . . . . . . . . . . . . . . . . . GYS2 . . . . . . . . . . . AEBP2 AEBP2

intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intron intergenic intron intron intron intron promoter promoter intergenic intergenic intergenic intergenic intergenic promoter intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intergenic intron intron intron intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intron intron

0.093 -0.096 0.175 0.079 0 0.231 0.137 -0.281 0.583 0.077 0.095 0.269 . . . 0.014 0.18 -0.119 0.212 . . -0.214 0.051 0.051 0.051 . . . 0.15 0.174 . . 0.144 . 1.585 . . . 0.16 . . 0.038 0.222 0.222 0.222 . . 0.047 0.12 . . -0.594 0.536 0.173 0.101 -0.08 0.158 -0.194 -0.069 -0.081 0.3 0.437 . 0.029 0.075 0.979 -0.167 0.217 0.005 0.169 . 0.02 . . 0.103 0.033 . . . . 0.017 0.274 0.18 -0.109

rs708752907 rs786503046 rs791777335 823202 rs7876 168676 rs7897 . 851470 rs7904 rs789911009 765195 rs7891 539647 rs7879 rs791403267 . . 281068 rs7868 rs789357703 rs792393451 . 077368 rs7878 361092 rs7921 . . 304868 rs7917 rs790230710 rs790230710 rs790230710 rs786337738 rs787073657 rs790522238 554703 rs7883 rs791858767 168510 rs7903 rs790736162 rs789788826 565422 rs7923 rs786390287 rs791886668 . rs703333250 rs789408815 rs790321352 rs791433919 rs791234072 323936 rs7904 323936 rs7904 323936 rs7904 rs790851123 rs791954785 rs789249126 rs791460113 rs696122658 105604 rs7910 rs793572838 rs793861932 rs791553967 rs790965057 rs786936851 417186 rs7926 . . rs791229785 rs787778496 854317 rs7920 rs792563610 . rs789405302 rs793617609 rs788974012 rs788401105 594962 rs7931 rs788722005 rs792063776 rs790298794 . rs787734815 rs791598239 rs790420648 rs790113860 rs787871933 rs789188126 rs789535652 rs792346090 104590 rs7936 . 076177 rs7868

2 3 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 3 3 3 2 3 3 3 2 2 2 2 2 2 2 2 2 2 2 2 3 4 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 3 3 3 2 2 2 2 2 2 2 2 2 3 2 2 2 4 2 2 2 2 2 2 4 2 2 3 2

AAAC.GTTT AAAC.GTTT AG.CT AT.AT AAAT.ATTT AAAC.GTTT AAAT.ATTT AG.CT AT.AT AC.GT AAG.CTT AAC.GTT AAC.GTT AAC.GTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AC.GT AAAC.GTTT AG.CT AG.CT AATC.GATT AC.GT AT.AT AAC.GTT AT.AT AT.AT AG.CT AG.CT AAAC.GTTT AC.GT AC.GT AG.CT AAG.CTT AC.GT AG.CT AC.GT AAAC.GTTT AC.GT AC.GT AAC.GTT AT.AT AAG.CTT AG.CT AC.GT AAAAAC.GTTTTT ATCC.GGAT AAAG.CTTT AAAC.GTTT AG.CT AC.GT AC.GT ACC.GGT AG.CT AC.GT AC.GT AAC.GTT AC.GT AC.GT AC.GT AAT.ATT AAAT.ATTT AG.CT ATCC.GGAT AG.CT AG.CT AAT.ATT AAAC.GTTT AGGG.CCCT AG.CT AAAC.GTTT AG.CT AAAC.GTTT AT.AT AG.CT AC.GT AC.GT AG.CT AG.CT AG.CT AG.CT AT.AT AT.AT AT.AT

5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5

57002078 57075331 57139998 57207395 57215150 57218740 57271827 57539939 57654693 57678205 57705137 57875505 57875505 57875505 57880580 57880580 57880580 58280881 58296248 58327749 58399288 58402884 58576414 58641927 59027724 59106173 59298521 59321546 59433199 59615080 59647563 59649191 59711975 59765979 60192297 60294076 60316124 60365584 60491369 60501932 60504262 60582290 60629468 60748295 60755669 60825047 60827344 60865139 60884578 60933457 60975661 60978296 61080613 61414619 61444369 61444369 61877438 61917578 62351996 62444185 62528315 62638880 63075232 63185951 63215970 63234730 63235580 63239469 63248284 63300016 63592694 63711797 63971735 63976656 63997225 64132941 64159002 64343133 64414198 64521553 64521553 64549810 64549810 64549810

57002099 57075357 57140008 57207408 57215173 57218758 57271841 57539957 57654706 57678221 57705149 57875524 57875524 57875524 57880610 57880610 57880610 58280891 58296275 58327764 58399299 58402907 58576432 58641941 59027745 59106183 59298530 59321555 59433223 59615111 59647577 59649216 59711989 59766003 60192307 60294086 60316141 60365617 60491381 60501960 60504275 60582301 60629484 60748322 60755680 60825067 60827361 60865165 60884601 60933467 60975670 60978310 61080625 61414634 61444383 61444383 61877454 61917588 62352010 62444197 62528332 62638903 63075242 63185986 63215979 63234743 63235593 63239483 63248303 63300027 63592723 63711815 63971760 63976668 63997237 64132955 64159012 64343146 64414208 64521562 64521562 64549835 64549835 64549835

5.5 6.75 5.5 7 6 4.75 3.75 9.5 7 8.5 4.33333 6.66667 6.66667 6.66667 7.75 7.75 7.75 5.5 7 8 6 6 9.5 7.5 7.33333 5.5 5 5 12.5 8 7.5 13 7.5 8.33333 5.5 5.5 9 8.5 6.5 14.5 4.66667 6 5.66667 14 6 3.5 4.5 6.75 6 5.5 5 7.5 4.33333 8 7.5 7.5 5.66667 5.5 7.5 6.5 6 6 5.5 9 5 7 4.66667 3.75 5 6 7.5 9.5 6.5 6.5 6.5 7.5 5.5 7 5.5 5 5 13 13 13

. ENSSSCT00000000633 ENSSSCT00000000633 . . . . . . . ENSSSCT00000000635 ENSSSCT00000031285 ENSSSCT00000000636 ENSSSCT00000027538 ENSSSCT00000031285 ENSSSCT00000000636 ENSSSCT00000027538 . . . . . . . . . . . . . ENSSSCT00000000643 ENSSSCT00000000643 ENSSSCT00000000643 . . . ENSSSCT00000000645 ENSSSCT00000000645 ENSSSCT00000027092 ENSSSCT00000027092 ENSSSCT00000027092 . . ENSSSCT00000000647 ENSSSCT00000000647 ENSSSCT00000000647 ENSSSCT00000000647 . . . ENSSSCT00000000649 ENSSSCT00000000649 . . ENSSSCT00000000658 ENSSSCT00000022782 . . . . . . . ENSSSCT00000031037 ENSSSCT00000031037 ENSSSCT00000031037 ENSSSCT00000031037 ENSSSCT00000031037 ENSSSCT00000031037 ENSSSCT00000031037 ENSSSCT00000000671 ENSSSCT00000000669 . ENSSSCT00000000678 . ENSSSCT00000000681 . . . ENSSSCT00000000703 ENSSSCT00000027764 ENSSSCT00000033773 ENSSSCT00000000700 ENSSSCT00000000699

. . . . . . . . . . PLCZ1 PIK3C2G PIK3C2G PIK3C2G PIK3C2G PIK3C2G PIK3C2G . . . . . . . . . . . . . SLC15A5 SLC15A5 SLC15A5 . . . . . . . . . . RERG RERG RERG RERG . . . ARHGDIB ARHGDIB . . ATF7IP ATF7IP . . . . . . . ETV6 ETV6 ETV6 ETV6 ETV6 ETV6 ETV6 LRP6 BCL2L14 . TAS2R9 . STYK1 . . . CLEC1A CLEC1A CLEC7A CLEC7A CLEC7A

intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic promoter promoter intron intergenic intergenic intergenic intron intron intron intron intron intergenic intergenic intron intron intron intron intergenic intergenic intergenic intron intron intergenic intergenic 3'utr 3'utr intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intron intron intron intergenic promoter intergenic intron intergenic intergenic intergenic intron intron intron intron intron

0.083 -0.061 0.17 0.047 -0.063 0.03 0.016 0.08 0.064 -0.031 -0.181 0.025 0.025 0.025 -0.012 -0.012 -0.012 0.061 . 0.224 -0.076 -0.066 -0.09 0.058 . 0.584 0.083 1.336 0.097 0.466 . 1.192 -0.015 0.485 . -0.353 0.544 0.029 1.45 . 0.023 0.155 0.101 0.735 0.013 -0.044 -0.003 0.227 -0.018 0.069 1.565 0.059 0.088 . 1.93 1.93 0.404 0.317 0.131 0.013 0.233 -0.089 0.209 0.013 -0.074 . 0.186 -0.145 0.777 -0.057 . -0.062 . -0.111 . 0.125 0.017 . 0.017 0.464 0.464 0.018 0.018 0.018

rs792524450 rs789182217 rs792370941 rs789265256 rs792187995 461000 rs7931 283973 rs7913 rs793216505 517309 rs7926 rs792398517 rs787313793 rs786500379 rs786500379 rs786500379 rs790745872 rs790745872 rs790745872 . rs790214617 rs793271519 . rs792850416 rs789976205 rs792416349 rs786863185 rs787509732 rs792431406 rs789456714 rs791481984 718007 rs7864 . rs788035808 rs789697643 rs787690384 . rs787514915 596185 rs7865 rs791115998 . . rs791232359 rs790422519 501323 rs7869 rs793211587 rs790351603 409014 rs7918 . rs790361374 rs786397930 . rs786598512 rs787673295 492492 rs7911 . . . rs789418723 . . rs786443298 rs793780894 262287 rs7929 rs788737517 615801 rs7885 . rs793715192 rs790377810 rs793559511 rs787448705 rs790858751 rs793700854 rs792818606 rs786924178 532659 rs7914 052750 rs7907 534258 rs7937 rs788817730 rs787533810 rs788257786 445047 rs7888 445047 rs7888 . . .

2 2 2 3 2 4 2 2 2 2 2 3 3 3 2 2 2 3 2 5 4 2 2 2 2 2 2 2 2 2 2 2 2 3 3 2 2 2 3 3 2 2 2 3 2 2 2 2 2 2 2 2 2 3 3 3 2 4 2 3 2 2 5 2 2 3 2 2 2 2 3 2 2 3 2 2 2 2 2 4 4 4 4 4

AT.AT AT.AT AG.CT AG.CT AG.CT AG.CT AG.CT AT.AT AAAC.GTTT AAAC.GTTT AAG.CTT AAAC.GTTT AAC.GTT AAC.GTT AAG.CTT AAAC.GTTT AT.AT AG.CT AAAC.GTTT AT.AT AAT.ATT AC.GT AG.CT AAT.ATT AAAC.GTTT AC.GT AC.GT AGC.GCT AAAC.GTTT AC.GT AC.GT AC.GT AC.GT AAAAT.ATTTT AAAAC.GTTTT AT.AT AG.CT ATC.GAT ACAT.ATGT AC.GT AAC.GTT AAAAC.GTTTT AAAAC.GTTTT AT.AT AT.AT AGG.CCT AAT.ATT ACAT.ATGT AAAT.ATTT AAT.ATT AAT.ATT AAT.ATT AAAG.CTTT AT.AT AT.AT AGG.CCT AAAG.CTTT AT.AT AAAT.ATTT AG.CT AT.AT ACAT.ATGT AT.AT AT.AT AAT.ATT AAG.CTT AAAC.GTTT AG.CT AC.GT AT.AT AT.AT AT.AT AC.GT AGAGGG.CCCTC AAAC.GTTT AC.GT AC.GT AC.GT AAAAAT.ATTTTT AAAAG.CTTTT AG.CT AAGG.CCTT AAAC.GTTT AAAAAG.CTTTTT

5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5

64549810 64549810 64552169 64552169 64552169 64552169 64552169 64733633 64759846 64759846 64881915 64892367 64911233 64911233 65000411 65007805 65405361 65472831 65602241 65637818 65940241 65963672 66310961 66517352 66631900 66675234 67344826 67348437 67381639 68098717 68133864 68241600 69775864 70017275 70343594 70563564 70578218 70614382 70623677 70758620 71309083 71361463 72070900 72089246 72177332 72650256 72658577 72777413 72779618 72804363 72804363 72804363 73048700 73095654 73152609 73412917 73732161 73813618 73820653 73951966 73963953 73964054 73980232 73995600 73997634 74134714 74639476 75026870 75173842 75378144 75378144 75460909 75548494 75601711 75603867 75617201 75624825 75629390 75648629 75716649 75764940 75793010 75944353 75985605

64549835 64549835 64552180 64552180 64552180 64552180 64552180 64733643 64759872 64759872 64881928 64892387 64911250 64911250 65000434 65007824 65405374 65472846 65602263 65637832 65940253 65963703 66310975 66517369 66631913 66675244 67344838 67348453 67381661 68098728 68133874 68241624 69775888 70017295 70343617 70563576 70578248 70614399 70623692 70758631 71309100 71361496 72070918 72089263 72177344 72650270 72658595 72777426 72779633 72804376 72804376 72804376 73048715 73095665 73152619 73412933 73732187 73813632 73820670 73951975 73963964 73964072 73980249 73995614 73997655 74134731 74639498 75026880 75173853 75378154 75378154 75460919 75548528 75601742 75603901 75617214 75624839 75629409 75648651 75716675 75764949 75793035 75944368 75985629

13 13 6 6 6 6 6 5.5 6.75 6.75 4.66667 5.25 6 6 8 5 7 8 5.75 7.5 4.33333 16 7.5 6 3.5 5.5 6.5 5.66667 5.75 6 5.5 12.5 12.5 4.2 4.8 6.5 15.5 6 4 6 6 6.8 3.8 9 6.5 5 6.33333 3.5 4 4.66667 4.66667 4.66667 4 6 5.5 5.66667 6.75 7.5 4.5 5 6 4.75 9 7.5 7.33333 6 5.75 5.5 6 5.5 5.5 5.5 17.5 5.33333 8.75 7 7.5 10 3.83333 5.4 5 6.5 4 4.16667

ENSSSCT00000000701 ENSSSCT00000033700 ENSSSCT00000000699 ENSSSCT00000033700 ENSSSCT00000000700 ENSSSCT00000033773 ENSSSCT00000000701 . ENSSSCT00000000707 ENSSSCT00000035148 . . ENSSSCT00000000709 ENSSSCT00000000708 . . . ENSSSCT00000000720 . . ENSSSCT00000027671 . ENSSSCT00000000742 ENSSSCT00000000754 . . . . . ENSSSCT00000000785 ENSSSCT00000000786 . ENSSSCT00000000812 ENSSSCT00000023353 ENSSSCT00000000817 ENSSSCT00000000819 ENSSSCT00000000819 ENSSSCT00000000819 ENSSSCT00000000819 . . . ENSSSCT00000031909 ENSSSCT00000031909 ENSSSCT00000000834 . . . . ENSSSCT00000028240 ENSSSCT00000000842 ENSSSCT00000027279 ENSSSCT00000028240 ENSSSCT00000028240 . ENSSSCT00000000843 ENSSSCT00000000845 ENSSSCT00000000846 ENSSSCT00000000846 ENSSSCT00000034370 ENSSSCT00000034370 ENSSSCT00000034370 ENSSSCT00000034370 ENSSSCT00000034370 ENSSSCT00000034370 . ENSSSCT00000000849 . ENSSSCT00000000855 ENSSSCT00000034945 ENSSSCT00000036262 . . . . . . . . . . . . .

CLEC7A intron CLEC7A intron CLEC7A intron CLEC7A intron CLEC7A intron CLEC7A intron CLEC7A intron . intergenic CLEC12A intron CLEC12A intron . intergenic . intergenic CD69 intron CD69 intron . intergenic . intergenic . intergenic A2ML1 intron . intergenic . intergenic PEX5 intron . intergenic LEPREL2 intron PIANP intron . intergenic . intergenic . intergenic . intergenic . intergenic RAD51AP1 intron C12orf4 intron . intergenic IQSEC3 intron KDM5A intron WNK1 intron RAB6IP2 intron RAB6IP2 intron RAB6IP2 intron RAB6IP2 intron . intergenic . intergenic . intergenic BCL2L13 intron BCL2L13 intron . intron . intergenic . intergenic . intergenic . intergenic CPNE8 intron CPNE8 intron CPNE8 intron CPNE8 intron CPNE8 intron . intergenic KIF21A intron ABCD2 intron C12orf40 intron C12orf40 intron SLC2A13 intron SLC2A13 intron SLC2A13 intron SLC2A13 intron SLC2A13 intron SLC2A13 intron . intergenic LRRK2 intron . intergenic CNTN1 intron CNTN1 intron CNTN1 intron . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic

0.018 0.018 0.021 0.021 0.021 0.021 0.021 . . . 0.147 -0.097 -0.071 -0.071 . . . . 0.23 0.13 0.16 . . 0.137 . . -0.055 -0.208 -0.115 0.626 -0.037 0.429 0.006 -0.135 0.199 . 0.031 0.163 . . 0.183 0.23 . 0.212 . . -0.012 0.003 0.257 0.126 0.126 0.126 0.153 -0.019 0.218 0.018 0.133 . . 0.118 0.023 -0.039 0.037 0.172 0.175 0.318 2.987 -0.242 0.022 0.259 0.259 . 0.456 0.154 0.072 0.047 0.026 0.09 -0.293 -0.09 -0.181 -0.068 -0.075 0.006

. . . . . . . rs793167888 175026 rs7936 175026 rs7936 rs692962230 057897 rs7937 rs788857275 rs788857275 rs789668336 rs789768111 . 619244 rs7873 rs709732225 rs791398221 rs694101583 273754 rs7913 . rs788577014 rs787391482 rs788931158 . rs789942600 rs793366423 rs787797665 . rs792077401 rs791057588 rs791439868 rs788953824 rs787191862 rs789975592 rs790187760 . . rs788454386 rs790004991 rs793830810 rs788640242 959999 rs7916 rs789553249 rs788780661 rs793640423 rs787994679 rs788736129 rs788736129 rs788736129 rs789089185 . 872384 rs7870 . rs786834847 rs790220822 rs788968218 . rs792926914 . . rs787077874 rs787993260 rs789571068 rs788464692 . rs786239328 rs789436177 rs789436177 rs787656390 638008 rs7913 . rs790961447 . rs790767195 261619 rs7923 rs790946606 rs788869162 rs792626424 . rs793046275 rs787787452

4 4 3 3 3 3 3 3 2 2 2 2 2 2 2 2 2 2 2 2 4 2 3 2 2 2 2 2 2 2 2 2 4 2 3 2 2 2 2 3 3 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 5 2 2 2 2 2 2 2 2 3 4 2 2 4 2 4 2 2 2 3 2 2

AC.GT AC.GT AAAT.ATTT AC.GT AAAC.GTTT AC.GT AT.AT AT.AT AT.AT AAG.CTT AC.GT AT.AT AAAAT.ATTTT AG.CT AC.GT AAG.CTT AAG.CTT AAG.CTT AAAT.ATTT ACACAT.ATGTGT AAC.GTT AT.AT AC.GT AT.AT AAAT.ATTT AAC.GTT AC.GT AGATAT.ATATCT AAAAT.ATTTT AAC.GTT AAATC.GATTT AAAG.CTTT AAAT.ATTT AATAT.ATATT AAAAG.CTTTT AAC.GTT AT.AT AT.AT AT.AT AT.AT AT.AT AAAT.ATTT AAAC.GTTT AAAT.ATTT AC.GT AAAAG.CTTTT AC.GT AATG.CATT AAACC.GGTTT AG.CT AAT.ATT AAAC.GTTT AAAAT.ATTTT ACC.GGT AC.GT AT.AT AC.GT AAAT.ATTT AAT.ATT AC.GT ATATC.GATAT AAGG.CCTT AAC.GTT AAAG.CTTT AAAC.GTTT AC.GT AC.GT AAAG.CTTT AC.GT AAAC.GTTT AAAAC.GTTTT AG.CT AG.CT AAAAC.GTTTT AT.AT AC.GT AC.GT AC.GT AC.GT AC.GT AC.GT AC.GT AC.GT AC.GT

5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5

76212044 76325340 76651777 76658063 76771663 76794813 77057866 77214784 77446778 77451208 77480222 77489406 77510071 77517113 77526666 77645597 77645597 77645597 77794536 77966222 78029012 78086027 78120065 78125336 78134529 78540246 78565118 78580040 78591323 78672140 78963036 79070827 79137934 79250357 79362709 79406359 79492188 79739655 79739655 79739655 79908706 79983942 80008702 80016827 80101801 80307234 80410764 80642879 81082452 81101898 81316067 81823019 81824174 81897633 82175623 82459452 82662042 82668577 83030451 83110990 83233315 83462394 83839954 83893623 83984098 84038931 84038931 84073364 84154401 84171786 84494053 84537279 84597858 84959338 85062200 85610631 85764617 85764617 85764617 85764617 85764617 85764617 85764617 85764617

76212054 76325349 76651788 76658077 76771686 76794823 77057877 77214794 77446789 77451219 77480232 77489417 77510096 77517138 77526678 77645608 77645608 77645608 77794554 77966246 78029028 78086036 78120084 78125346 78134547 78540262 78565131 78580077 78591341 78672159 78963064 79070843 79137952 79250385 79362728 79406384 79492198 79739667 79739667 79739667 79908716 79983962 80008715 80016847 80101819 80307260 80410775 80642906 81082468 81101908 81316083 81823033 81824195 81897648 82175633 82459462 82662057 82668591 83030476 83111000 83233329 83462412 83839967 83893637 83984118 84038950 84038950 84073382 84154411 84171804 84494077 84537295 84597872 84959359 85062210 85610644 85764627 85764627 85764627 85764627 85764627 85764627 85764627 85764627

5.5 5 3 7.5 6 5.5 6 5.5 6 4 5.5 6 5.2 13 6.5 4 4 4 4.75 4.16667 5.66667 5 10 5.5 4.75 5.66667 7 6.33333 3.8 6.66667 5.8 4.25 4.75 5.8 4 8.66667 5.5 6.5 6.5 6.5 5.5 5.25 3.5 5.25 9.5 5.4 6 7 3.4 5.5 5.66667 3.75 4.4 5.33333 5.5 5.5 8 3.75 8.66667 5.5 3 4.75 4.66667 3.75 5.25 10 10 4.75 5.5 4.75 5 8.5 7.5 4.4 5.5 7 5.5 5.5 5.5 5.5 5.5 5.5 5.5 5.5

. . intergenic ENSSSCT00000000859 PPHLN1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000000862 ADAMTS20 intron ENSSSCT00000000862 ADAMTS20 intron ENSSSCT00000000862 ADAMTS20 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000000867 PUS7L intron ENSSSCT00000000866 IRAK4 promoter ENSSSCT00000035861 IRAK4 promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000000870 NELL2 intron ENSSSCT00000000870 NELL2 intron ENSSSCT00000000870 NELL2 intron ENSSSCT00000000870 NELL2 intron ENSSSCT00000000870 NELL2 intron . . intergenic . . intergenic ENSSSCT00000000873 ANO6 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000023077 SCAF11 intron ENSSSCT00000031177 SCAF11 intron ENSSSCT00000000875 SCAF11 intron . . intergenic ENSSSCT00000000876 SLC38A1 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000029189 SLC38A4 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000032274 VDR intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000025699 . intron ENSSSCT00000000915 APPL2 intron ENSSSCT00000000915 APPL2 intron ENSSSCT00000000911 SLC41A2 intron ENSSSCT00000000911 SLC41A2 intron ENSSSCT00000000910 CHST11 intron ENSSSCT00000000910 CHST11 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000000926 HSP90B1 intron ENSSSCT00000000925 GLT8D2 intron ENSSSCT00000000926 HSP90B1 intron ENSSSCT00000000930 . intron ENSSSCT00000000930 . intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000022294 . promoter . . intergenic ENSSSCT00000034902 IGFI intron ENSSSCT00000034323 IGFI intron ENSSSCT00000034198 IGFI intron ENSSSCT00000035604 IGFI intron ENSSSCT00000000936 IGFI intron ENSSSCT00000035532 IGFI intron ENSSSCT00000035024 IGFI intron ENSSSCT00000034991 IGFI intron

. 0.131 . . -0.22 0.108 . . 0.126 -0.091 -0.097 0.065 0.03 0.085 0.759 0.106 0.106 0.106 0.073 0.226 . -0.085 0.032 0.027 0.117 0.104 -0.068 0.004 0.107 0.06 . . . 0.196 0.012 . . 1.81 1.81 1.81 0.016 0.393 . -0.078 0.049 . 0.105 -0.091 0.007 0.366 0.034 . . -0.286 0.181 . . -0.381 0.063 0.022 -0.069 -0.069 0.278 . 0.221 -0.256 -0.256 . -0.021 0.333 . -0.2 0.245 0.103 0.002 1.757 0.179 0.179 0.179 0.179 0.179 0.179 0.179 0.179

rs786917626 . rs793759285 rs791570050 rs790424050 rs789005193 . rs786366496 rs793771542 rs786787004 rs786759565 . 812515 rs7918 rs792516835 rs788107800 935086 rs7892 935086 rs7892 935086 rs7892 . rs792513865 rs791367968 . rs793079175 rs789274540 rs788974308 rs789330256 rs789028190 rs790746379 rs790749678 rs786710211 rs790556993 538931 rs7937 rs788960988 030703 rs7904 549611 rs7879 538525 rs7925 . 828895 rs7882 828895 rs7882 828895 rs7882 . 878003 rs7936 rs790227746 215980 rs7911 rs792963302 124519 rs7901 rs787655268 rs791469144 rs790882818 . rs792773981 rs792173823 rs793807236 rs792038136 226132 rs7896 . rs791181165 463065 rs7879 rs791433966 rs792503657 rs786209092 rs787588213 070520 rs7938 rs786711417 rs792320154 rs789746840 rs789746840 rs788422493 . 169455 rs7910 266008 rs7871 . . . rs793488247 rs789162522 . . . . . . . .

2 2 2 4 2 2 3 2 2 2 3 2 2 2 2 3 3 3 2 2 2 3 2 3 2 4 2 3 2 2 2 2 2 2 3 2 3 2 2 2 4 2 2 2 5 2 2 2 2 2 2 2 4 2 2 2 3 2 2 2 2 2 2 2 2 4 4 2 2 2 2 2 2 2 3 2 5 5 5 5 5 5 5 5

AT.AT AC.GT AAAC.GTTT AAC.GTT AAC.GTT AAC.GTT AG.CT AAAC.GTTT AAC.GTT AAAAC.GTTTT AAAAC.GTTTT AAAG.CTTT AAC.GTT AC.GT AAC.GTT AAAC.GTTT AATC.GATT AAAT.ATTT AAAC.GTTT AAAC.GTTT AAC.GTT AT.AT AC.GT AC.GT AAAC.GTTT AAT.ATT AAG.CTT AT.AT AGATAT.ATATCT ACAT.ATGT AAAAT.ATTTT AT.AT AT.AT AT.AT AAAT.ATTT AATG.CATT AAAAC.GTTTT AAAAC.GTTTT AC.GT AAAG.CTTT AG.CT AAAC.GTTT AC.GT AT.AT AG.CT AAAC.GTTT AC.GT AC.GT AAT.ATT AG.CT AAAG.CTTT AT.AT AC.GT AAC.GTT AAAT.ATTT AG.CT AAAT.ATTT AC.GT AAAC.GTTT AAAG.CTTT AAT.ATT AAAT.ATTT AATG.CATT AC.GT AT.AT AT.AT ACAT.ATGT AAAAC.GTTTT AAAT.ATTT AAAC.GTTT AAAAG.CTTTT AAGC.GCTT AAC.GTT AAAT.ATTT AAAAC.GTTTT AAAAC.GTTTT AT.AT AATG.CATT AAAAC.GTTTT AAAAC.GTTTT AC.GT AC.GT AT.AT AT.AT

5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5

85810054 86069438 86369160 86401970 86401970 86401970 86424190 86472143 86472247 86527346 86527346 86570806 86602807 86688523 86700801 86763936 86772625 86775082 86784294 86824214 86862428 86937216 87212135 87382682 87434006 87495988 87728622 87741299 87743022 87746940 87955042 88009909 88009909 88009909 88495827 88529401 88653480 88924301 89014202 89122176 89143955 89148058 89223538 89253502 89639968 89643998 89666104 89882086 90235614 90239972 90276941 90366564 90497295 90503700 90524433 90578666 90617058 90699270 91044547 91073892 91130172 91140280 91178665 91206553 91289788 91409669 91544997 91629314 91833558 91896256 91923719 91987110 92133455 92177803 92651889 92762822 92775891 92993788 93470079 93470079 93471864 93471864 93496857 93496857

85810070 86069461 86369177 86401983 86401983 86401983 86424201 86472157 86472258 86527367 86527367 86570823 86602818 86688539 86700813 86763948 86772644 86775110 86784312 86824232 86862443 86937226 87212152 87382703 87434017 87496001 87728638 87741318 87743041 87746966 87955060 88009932 88009932 88009932 88495843 88529419 88653498 88924324 89014212 89122197 89143970 89148080 89223548 89253513 89639979 89644009 89666115 89882105 90235637 90239982 90276967 90366573 90497305 90503713 90524467 90578675 90617076 90699284 91044562 91073909 91130185 91140313 91178691 91206569 91289809 91409679 91545018 91629336 91833571 91896288 91923739 91987137 92133468 92177830 92651918 92762842 92775901 92993810 93470098 93470098 93471883 93471883 93496867 93496867

8.5 12 4.5 4.66667 4.66667 4.66667 6 3.75 4 4.4 4.4 4.5 4 8.5 4.33333 3.25 5 7.25 4.75 4.75 5.33333 5.5 9 11 3 4.66667 5.66667 10 3.33333 6.75 3.8 12 12 12 4.25 4.75 3.8 4.8 5.5 5.5 8 5.75 5.5 6 6 3 6 10 8 5.5 6.75 5 5.5 4.66667 8.75 5 4.75 7.5 4 4.5 4.66667 8.5 6.75 8.5 11 5.5 5.5 4.6 3.5 8.25 4.2 7 4.66667 7 6 4.2 5.5 5.75 4 4 10 10 5.5 5.5

. . intergenic ENSSSCT00000000939 . intron ENSSSCT00000028915 . intron ENSSSCT00000028915 . intron ENSSSCT00000000941 . intron ENSSSCT00000029378 U2 promoter . . intergenic ENSSSCT00000000943 CHPT1 intron ENSSSCT00000000943 CHPT1 intron ENSSSCT00000000945 MYBPC1 intron ENSSSCT00000030865 . intron ENSSSCT00000000945 MYBPC1 intron ENSSSCT00000000945 MYBPC1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000000949 UTP20 intron ENSSSCT00000000949 UTP20 intron . . intergenic ENSSSCT00000000956 ANO4 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000028017UHRF1BP1L intron ENSSSCT00000000960 . intron ENSSSCT00000000963 . intron . . intergenic ENSSSCT00000000964 . intron ENSSSCT00000000964 . intron ENSSSCT00000000966 . intron ENSSSCT00000000966 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000000971 . intron ENSSSCT00000000971 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000000974 NEDD1 promoter . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000000980 NTN4 intron ENSSSCT00000000980 NTN4 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000000989 NDUFA12 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000032383 CCDC41 intron ENSSSCT00000024929 CCDC41 intron ENSSSCT00000032383 CCDC41 intron ENSSSCT00000024929 CCDC41 intron ENSSSCT00000032383 CCDC41 intron ENSSSCT00000024929 CCDC41 intron

0.076 0.082 . 1.907 1.907 1.907 . . . . . 1.926 0.149 . . 0.375 0.162 . 0.233 -0.264 -0.064 . 0.027 0.126 0.451 0.081 -0.074 0.04 0.161 . 0.208 0.192 0.192 0.192 0.363 0.084 -0.036 0.137 0.119 0.23 0.108 . 0.055 . 0.034 1.216 0.253 . 0.402 -0.014 0.618 0.521 -0.089 0.517 0.191 -0.044 0.081 -0.116 0.106 . 0.005 0.087 0.042 . 0.217 . . . . 0.834 . 0.316 . . 0.267 . 0.388 -0.438 . . . . . .

219375 rs7924 . rs790634353 rs787480497 rs787480497 rs787480497 226369 rs7874 394772 rs7900 rs707653662 rs789583802 rs789583802 rs790668456 rs790101476 . rs787814525 rs786247492 968426 rs7907 717248 rs7872 382631 rs7887 rs789181836 rs788414750 . rs790804608 rs793787852 rs787489961 rs789824405 rs701341248 790947 rs7912 rs793614187 547165 rs7931 rs787671008 221515 rs7891 221515 rs7891 221515 rs7891 . rs789115589 rs791420906 295441 rs7938 525853 rs7894 rs790593233 . 720081 rs7898 rs786450670 rs793296685 rs791776374 rs786821587 rs790384701 rs790553117 500606 rs7921 . . rs793425664 rs788127717 rs793695733 rs792718994 rs792615175 rs786429608 rs792364960 . . rs787361439 . rs792812403 rs787914436 . rs790224224 rs791163655 rs787188181 rs786265279 754334 rs7868 rs786469481 rs790002367 rs788937456 965972 rs7901 430839 rs7878 rs791602523 rs791680818 rs791853385 rs786348283 rs786348283 rs793749089 rs793749089 416225 rs7907 416225 rs7907

2 2 2 2 2 2 4 2 2 3 3 2 3 4 3 2 2 2 2 3 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 3 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2

AC.GT AC.GT AAAC.GTTT AAAC.GTTT ATC.GAT AG.CT AAAT.ATTT AG.CT AGATAT.ATATCT ATC.GAT AAAAT.ATTTT AC.GT AG.CT AAG.CTT AAAAT.ATTTT AGC.GCT AAAAG.CTTTT AT.AT AAAC.GTTT AAAAT.ATTTT AAAC.GTTT AAAC.GTTT AC.GT AAT.ATT AT.AT AG.CT AGC.GCT AG.CT AAT.ATT AAAAAC.GTTTTT AAAAC.GTTTT ACAG.CTGT AC.GT AG.CT AG.CT AAAC.GTTT AT.AT AAC.GTT AAACC.GGTTT AG.CT AT.AT AAAC.GTTT AC.GT AAAC.GTTT AC.GT AAAAAT.ATTTTT AT.AT AG.CT AC.GT AAAC.GTTT AT.AT AG.CT AAT.ATT AAAC.GTTT ACAT.ATGT AAAC.GTTT AAG.CTT AAAAC.GTTTT AC.GT AAT.ATT AAAAC.GTTTT AG.CT AC.GT AAC.GTT AAC.GTT AAAG.CTTT AATG.CATT AAAT.ATTT AAAT.ATTT AAC.GTT AC.GT AAAG.CTTT AT.AT AC.GT AC.GT AAAT.ATTT AAAT.ATTT AAAAC.GTTTT AC.GT ACAT.ATGT AAAAAT.ATTTTT AC.GT AAAAC.GTTTT AAAC.GTTT

5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5

93501766 93501766 93516028 93516028 93664443 93672477 93724116 93726409 93825480 94027660 94331408 94379160 94678481 94689673 94948818 95015933 95549472 95561483 96153246 96376547 96478089 96746480 96758071 96924500 97232768 97291369 97486328 97849161 97980247 98127633 98136774 98240590 98519794 98579561 98740771 98986513 99038056 99184652 99232719 99252202 99448667 99543046 99567114 99635380 99655523 99739353 99777775 99781165 99805667 99835855 100171373 100405143 100489003 100586993 100597485 100664482 100670813 100713210 100831729 100924308 101229552 101334939 101366158 101382779 101581153 101824015 101836650 102429164 102500583 102521978 102528401 102760046 102866686 103066996 103089638 103102881 103153372 103165836 103238932 103340754 103413916 103553044 103633421 103640993

93501778 93501778 93516042 93516042 93664464 93672487 93724132 93726418 93825505 94027672 94331423 94379174 94678492 94689689 94948834 95015951 95549495 95561500 96153272 96376562 96478107 96746494 96758084 96924529 97232802 97291379 97486348 97849175 97980258 98127654 98136789 98240612 98519808 98579583 98740781 98986531 99038067 99184668 99232742 99252211 99448677 99543065 99567124 99635394 99655532 99739374 99777785 99781176 99805682 99835873 100171394 100405166 100489027 100587011 100597503 100664518 100670826 100713225 100831739 100924321 101229566 101334951 101366178 101382792 101581176 101824026 101836680 102429178 102500601 102521997 102528413 102760061 102866696 103067007 103089659 103102896 103153391 103165854 103238943 103340788 103413937 103553055 103633441 103641012

6.5 6.5 3.75 3.75 7.33333 5.5 4.25 5 4.33333 4.33333 3.2 7.5 6 5.66667 3.4 6.33333 4.8 9 6.75 3.2 4.75 3.75 7 10 17.5 5.5 7 7.5 4 3.66667 3.2 5.75 7.5 11.5 5.5 4.75 6 5.66667 4.8 5 5.5 5 5.5 3.75 5 3.66667 5.5 6 8 4.75 11 12 8.33333 4.75 4.75 9.25 4.66667 3.2 5.5 4.66667 3 6.5 10.5 4.66667 8 3 7.75 3.75 4.75 6.66667 6.5 4 5.5 6 11 4 5 3.8 6 8.75 3.66667 6 4.2 5

ENSSSCT00000032383 ENSSSCT00000024929 ENSSSCT00000032383 ENSSSCT00000024929 . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000001004 . . . . . . . . ENSSSCT00000001012 ENSSSCT00000001009 . . . . . . . . . . . . . . . . . . . . ENSSSCT00000001016 ENSSSCT00000001016 . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000030219 ENSSSCT00000030219 ENSSSCT00000030219

CCDC41 CCDC41 CCDC41 CCDC41 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . TMTC3 C12orf50 . . . . . . . . . . . . . . . . . . . . MGAT4C MGAT4C . . . . . . . . . . . . . . . . . . . . . . . .

intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron

. . 0.142 0.142 0.289 0.067 0.503 -0.047 . 0.013 . . 0.139 0.761 0.048 0.177 0.328 0.093 . . . . 0.044 -0.093 0.755 . 0.112 . 0.068 0.104 0.414 -0.089 . 0.036 . 0.084 0.238 . 0.094 . 0.016 . 0.242 0.217 0.18 -0.311 0.091 . 0.025 0.408 0.807 . . 0.104 . 0.324 -0.003 0.264 -0.098 . 0.17 -0.239 0.035 0.539 0.143 0.025 0.017 . . 0.006 . 0.047 . -0.046 -0.006 . 0.178 0.092 0.516 . 0.268 0.006 0.395 0.043

rs792519525 rs792519525 rs792607054 rs792607054 rs792883074 655201 rs7930 518625 rs7938 484670 rs7922 rs791592558 rs787407989 rs787132705 . rs791125648 rs792990085 799768 rs7897 rs712914937 448912 rs7898 rs791093334 rs791189165 rs787972499 rs786768232 rs786628520 . . rs793437995 . rs789068530 rs786742080 519913 rs7916 rs789887170 . rs788528592 rs788477120 rs788329719 rs789800713 . rs787082636 rs791776910 rs792408587 . rs793140210 rs792446462 rs789490730 rs791164280 . 156633 rs7898 rs786751765 rs786744983 . rs788575706 . rs790633921 rs791926296 rs789592931 152025 rs7868 883014 rs7894 rs787028025 rs788748061 . rs786986584 rs791538043 868063 rs7908 . rs792371523 rs792113919 . rs790306807 rs789910343 rs788274717 rs787471661 rs786707720 336271 rs7887 . rs788166947 712421 rs7906 182147 rs7931 rs713230482 rs787448293 rs789520057 . rs791353114 . 976939 rs7931 704214 rs7914

2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 3 2 2 2 2 4 2 2 2 2 3 2 2 2 2 2 2 4 2 2 4 2 2 2 3 3 2 3 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 4 2 3

AC.GT AAAT.ATTT AC.GT AT.AT AAAC.GTTT AAAC.GTTT AG.CT AGG.CCT AAC.GTT AT.AT AAGC.GCTT AAAAC.GTTTT AC.GT AATG.CATT AC.GT AAC.GTT AGC.GCT AAAC.GTTT AC.GT AAG.CTT ACAT.ATGT AAAT.ATTT AAAC.GTTT AAC.GTT ACATAT.ATATGT AC.GT AAAAC.GTTTT AAAT.ATTT AAAC.GTTT AAAC.GTTT AAT.ATT AAT.ATT AAAC.GTTT AAAC.GTTT AG.CT AC.GT AAAC.GTTT AT.AT AC.GT AAAAG.CTTTT AAAAC.GTTTT ACAG.CTGT AAT.ATT AT.AT AAAG.CTTT AC.GT AAC.GTT CCCG.CGGG AAC.GTT AC.GT AC.GT AC.GT AAAG.CTTT AAT.ATT AAC.GTT AT.AT AAAT.ATTT AG.CT AGGG.CCCT AT.AT AG.CT AC.GT AC.GT AAAAC.GTTTT AC.GT AAAC.GTTT ACC.GGT AC.GT AC.GT AAT.ATT AAG.CTT AAAT.ATTT AAC.GTT AC.GT AC.GT AAAC.GTTT AAAAC.GTTTT AAAC.GTTT AT.AT AAAT.ATTT AC.GT AAAG.CTTT ACGG.CCGT AAAC.GTTT

5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6

103844708 103853189 104481681 104651246 104709317 104710553 105124433 105403210 105635855 105694646 105817925 105877225 105934008 106040257 106561427 106608966 106922442 107240790 107321289 107327869 107332071 107332126 107749297 107752512 107789606 107953362 108084154 108163036 108215626 108215626 108228264 108228264 108316282 108428668 108551564 108700631 108752416 108839106 108933984 108953723 109230938 109629922 110140135 111124216 111267203 111336563 378111 871151 950394 1808171 2090337 2096963 2153902 2774126 5362612 5365210 5372422 5478002 5516330 5609288 5625620 5723333 6037174 6225985 6724703 6746198 7120597 7254719 7255807 7423480 7456080 7628139 8224735 8238221 8303238 8581625 9241129 9265295 9335214 9453824 9463270 9473982 9779838 10319287

103844718 103853203 104481690 104651258 104709331 104710578 105124443 105403236 105635876 105694655 105817939 105877247 105934027 106040272 106561441 106608979 106922461 107240804 107321304 107327890 107332087 107332138 107749319 107752526 107789624 107953376 108084177 108163051 108215643 108215643 108228278 108228278 108316297 108428685 108551574 108700649 108752448 108839115 108934003 108953743 109230963 109629947 110140150 111124228 111267225 111336580 378123 871172 950418 1808182 2090359 2096972 2153933 2774139 5362634 5365223 5372434 5478018 5516346 5609298 5625631 5723349 6037192 6226010 6724719 6746215 7120614 7254730 7255833 7423497 7456093 7628156 8224746 8238233 8303257 8581644 9241151 9265308 9335224 9453850 9463294 9473996 9779854 10319301

5.5 3.75 5 6.5 3.75 6.5 5.5 9 7.33333 5 3.75 4.6 10 4 7.5 4.66667 6.66667 3.75 8 7.33333 4.25 3.25 5.75 5 3.16667 7.5 4.8 4 4.5 4.5 5 5 4 4.5 5.5 9.5 8.25 5 10 4.2 5.2 6.5 5.33333 6.5 5.75 9 4.33333 5.5 8.33333 6 11.5 5 8 4.66667 7.66667 7 3.25 8.5 4.25 5.5 6 8.5 9.5 5.2 8.5 4.5 6 6 13.5 6 4.66667 4.5 4 6.5 10 5 4.6 3.5 5.5 6.75 12.5 3.75 4.25 3.75

ENSSSCT00000029091 . intron ENSSSCT00000029091 . intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000001028 PPFIA2 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000001032 OTOGL intron ENSSSCT00000001032 OTOGL intron . . intergenic . . intergenic ENSSSCT00000028012 PPP1R12A intron ENSSSCT00000001037 SYT1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000029790 . intron ENSSSCT00000026141 . intron ENSSSCT00000029790 . intron ENSSSCT00000026141 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000031647 FANCA promoter ENSSSCT00000026558ssc-mir-4332promoter . . intergenic ENSSSCT00000002944 JPH3 intron ENSSSCT00000002948 C16orf95 intron ENSSSCT00000002948 C16orf95 intron . . intergenic ENSSSCT00000002951 MTHFSD intron ENSSSCT00000002977 CDH13 intron ENSSSCT00000002977 CDH13 promoter . . intergenic . . intergenic . . intergenic ENSSSCT00000031996 . intron ENSSSCT00000031996 . intron ENSSSCT00000031996 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000002982 CMIP intron ENSSSCT00000002982 CMIP intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

0.014 0.314 0.041 0.036 0.007 -0.043 -0.011 0.062 0.046 . 0.109 . 1.535 0.151 -0.146 0.066 0.276 -0.036 -0.034 0.114 0.306 0.281 . . 0.058 -0.047 0.025 0.37 0.025 0.025 0.043 0.043 -0.143 -0.18 -0.337 1.184 0.47 . 0.117 0.444 0.146 0.149 0.089 . . -0.335 . . . . . . . 0.083 0.013 -0.167 0.23 -0.272 -0.08 0.483 -0.005 -0.404 . -0.215 0.506 0.03 . -0.498 -0.065 . -0.237 -0.089 -0.18 -0.266 -0.099 1.357 -0.212 -0.055 0.517 -0.102 -0.04 0.638 0.055 -0.166

rs792339741 538279 rs7914 . 081602 rs7873 701516 rs7926 rs789579235 rs792273119 464875 rs7862 rs787854262 . . 622441 rs7901 253799 rs7904 rs792452297 rs787288510 rs790441227 592860 rs7903 rs792153024 777334 rs7888 rs704144022 rs786450405 . 925948 rs7930 rs789608839 490061 rs7909 rs788680210 926866 rs7895 904751 rs7936 rs786429846 rs786429846 . . rs786697709 658384 rs7918 rs787444513 . 786650 rs7918 rs793366402 . rs791147373 rs789009525 rs793288320 . rs791670373 rs790388463 . rs792311531 . 447685 rs7919 rs786537211 . . . rs788889925 rs789835452 734637 rs7928 rs786459183 641981 rs7926 rs788017161 rs787469867 . rs791377347 rs787796378 . rs787628292 rs788833230 rs792010823 745519 rs7893 rs787202640 . rs788634545 rs791685293 . rs793656766 rs793458584 rs789251516 rs791592969 rs793372061 . 130217 rs7938 632942 rs7886 rs788625446 rs789563233 rs786727791

2 2 2 2 2 2 2 2 2 3 2 2 2 2 5 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 3 2 3 2 3 2 2 2 2 2 2 2 2 2 2 4 2 4 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 3 4 2 2 2 2 4 2 2 2 2 3 3 3 2 2 2

AC.GT AC.GT AAAT.ATTT AAAC.GTTT AG.CT AC.GT AAAAAT.ATTTTT AT.AT AAAAC.GTTTT AAC.GTT AAAT.ATTT AC.GT AT.AT AAAC.GTTT AT.AT AAAC.GTTT AAAT.ATTT AGG.CCT AC.GT AAAC.GTTT AAAC.GTTT AG.CT AAAC.GTTT AAAT.ATTT AAC.GTT AAAAC.GTTTT AC.GT AAG.CTT AG.CT AC.GT AAAC.GTTT AT.AT AAAT.ATTT AGATAT.ATATCT AAGG.CCTT AAAT.ATTT AT.AT AAC.GTT AT.AT AC.GT AAAT.ATTT AC.GT AG.CT AT.AT AT.AT AG.CT AC.GT AAAAAG.CTTTTT AAAAC.GTTTT AC.GT AG.CT AC.GT AC.GT AAC.GTT AAAAT.ATTTT AT.AT AT.AT AG.CT AG.CT AC.GT AAAC.GTTT AC.GT AAAC.GTTT AC.GT AC.GT ACTC.GAGT ATCC.GGAT AAAT.ATTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAG.CTTT AT.AT AAC.GTT AAAT.ATTT AC.GT AAAC.GTTT ACAT.ATGT AAC.GTT ACC.GGT AAAAC.GTTTT AC.GT AAT.ATT AC.GT

6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6

10652123 10780709 10799819 10932857 11175333 11217572 11271803 11277409 11516966 11594402 11613189 11663713 11793005 11852390 11975349 11988354 12287445 12430547 12472449 12603088 12654044 12835665 12863975 13005970 13041104 13248535 13369712 13626375 13639120 13685755 13686298 13791107 13882584 13979674 14406477 14737527 14767978 14949942 15002446 15183552 15664397 15772699 15783251 15853618 15866361 15874807 15875040 15931495 15991205 16006098 16021914 16057764 16063969 16235596 16541868 16618840 17023272 17203467 17235162 17301766 17318233 17828278 17956378 18061804 18133876 18276711 18280224 18384609 18401161 18418121 18418121 18525393 18715904 18798448 18850230 19005040 19010162 19189278 19249501 19541590 19636054 19783751 20010193 20544654

10652139 10780727 10799833 10932873 11175345 11217598 11271832 11277420 11516984 11594418 11613209 11663733 11793035 11852412 11975358 11988374 12287472 12430561 12472463 12603108 12654063 12835682 12863995 13005988 13041120 13248558 13369739 13626393 13639131 13685764 13686312 13791119 13882601 13979703 14406495 14737549 14767992 14949956 15002462 15183565 15664411 15772723 15783269 15853629 15866371 15874831 15875057 15931520 15991223 16006109 16021924 16057773 16063982 16235609 16541891 16618851 17023287 17203477 17235171 17301787 17318257 17828287 17956409 18061813 18133895 18276732 18280252 18384622 18401182 18418148 18418148 18525412 18715916 18798463 18850261 19005061 19010176 19189293 19249519 19541602 19636077 19783766 20010209 20544664

8.5 9.5 3.75 4.25 6.5 13.5 5 6 3.8 5.66667 5.25 10.5 15.5 5.75 5 5.25 7 5 7.5 5.25 5 9 5.25 4.75 5.66667 4.8 14 6.33333 6 5 3.75 6.5 4.5 5 4.75 5.75 7.5 5 8.5 7 3.75 12.5 9.5 6 5.5 12.5 9 4.33333 3.8 6 5.5 5 7 4.66667 4.8 6 8 5.5 5 11 6.25 5 8 5 10 5.5 7.25 3.5 5.5 7 7 5 6.5 5.33333 8 11 3.75 4 6.33333 4.33333 4.8 8 5.66667 5.5

. . . . . . . . ENSSSCT00000032493 . ENSSSCT00000032493 . ENSSSCT00000032493 . ENSSSCT00000032493 . . . . . . . . . . . . . ENSSSCT00000003001GABARAPL ENSSSCT00000003002 . . . . . . . . . ENSSSCT00000028190 . ENSSSCT00000003012 FA2H . . ENSSSCT00000030720 GLG1 ENSSSCT00000030720 GLG1 ENSSSCT00000003016 . ENSSSCT00000003017 AARS . . . . . . . . ENSSSCT00000003024 . . . ENSSSCT00000003034 ZNF23 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000003119 ARL2BP . . . . . . ENSSSCT00000003111 CNGB1 ENSSSCT00000003106 MMP15 ENSSSCT00000003104 CSNK2A2 ENSSSCT00000003103 . . . . . . . . . ENSSSCT00000023952 CNOT1 ENSSSCT00000003099 CNOT1 . . . . . . . . . . . . . . . . . . . . . . . . . .

intergenic intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic promoter intron intergenic intergenic intergenic intergenic intron intron intergenic intron intron intron intron intergenic intergenic intergenic intergenic intron intergenic promoter intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

-0.179 0.008 . -0.121 0.218 0.034 . . . . 0.339 . 0.53 . 0.141 . . 0.836 . 0.216 0.041 -0.215 . . . . -0.399 . -0.011 -0.221 . . 0.064 . . 0.147 . . 0.022 -0.008 0.228 0.845 -0.025 . 0.032 1.078 1.534 0.197 -0.03 0.051 0.006 0.026 0.611 . . . . 1.921 0.21 -0.084 -0.275 0.982 -0.015 -0.072 . -0.008 0.093 . . 0.14 0.14 0.163 . . 0.162 0.059 0.229 0.019 . -0.09 . -0.079 . -0.131

rs787288479 . . rs786943940 rs791152904 rs791636009 099013 rs7883 . rs793193992 993031 rs7870 rs791754170 rs789273733 rs789115220 rs786391027 . . rs793138834 rs793718079 rs788706545 rs789505479 rs788701712 619668 rs7901 rs786733053 rs788610045 rs788234911 rs787384955 414065 rs7868 rs793078644 rs789296301 rs791768728 rs787861254 rs790429271 242146 rs7891 rs786691656 163218 rs7900 rs792698507 . 661033 rs7917 . rs787695299 rs790653835 . rs792829310 rs786775775 rs691475087 rs786210449 rs791872566 rs790180018 rs789437113 rs786447286 . . rs786227279 rs791615076 rs787947947 rs787942805 . 905991 rs7886 rs790330890 . rs793834986 rs787124819 rs786570868 . rs791530019 603650 rs7887 744926 rs7917 rs790307644 rs792345757 rs787328756 rs787328756 343443 rs7865 021876 rs7928 rs789663312 rs788451449 . 344434 rs7864 299639 rs7925 380512 rs6947 . rs789700371 . rs696368341 .

3 5 2 2 2 2 2 3 2 2 2 4 2 2 2 2 2 2 3 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 3 2 2 4 2 3 2 2 2 2 3 2 2 2 2 2 2 2 2 2 4 2 2 4 2 3 2 2 2 2 3 2 2 2 2 3 2 2 2 2 2 2 3 2 2 3 2 4

AGAT.ATCT AAAT.ATTT AC.GT AAT.ATT AAC.GTT ACAG.CTGT AC.GT AG.CT AAC.GTT AT.AT ACT.AGT AAAC.GTTT AAC.GTT AG.CT AAC.GTT AAAC.GTTT AAAC.GTTT AG.CT AC.GT AAAC.GTTT AAAAT.ATTTT AC.GT AC.GT AT.AT AC.GT AC.GT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AC.GT AC.GT AC.GT AC.GT AC.GT AAAT.ATTT AAT.ATT AAAC.GTTT ACC.GGT AATG.CATT AT.AT AG.CT AG.CT AC.GT AAAC.GTTT AGGG.CCCT AAAC.GTTT AAAAAC.GTTTTT AC.GT AG.CT AAAT.ATTT AAAAG.CTTTT AGC.GCT AG.CT AG.CT AAAC.GTTT AAT.ATT AAC.GTT AAAC.GTTT AAAAC.GTTTT AT.AT ATCC.GGAT AAG.CTT AAAG.CTTT AC.GT AC.GT AT.AT AC.GT AG.CT AAAAC.GTTTT AC.GT AC.GT AG.CT AAAAT.ATTTT AC.GT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT ATC.GAT AG.CT AAAAG.CTTTT AG.CT

6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6

20566193 20865349 20973058 21239921 21366631 21488229 21504952 21594205 21618019 21624146 21723169 21723577 21833661 21840078 21870140 21901151 22054085 22132905 22556037 22592472 22621776 22755687 22821417 22905956 23184335 23478550 23731863 23731863 23731863 23731863 23747861 23747861 23747861 23747861 23747861 23838643 23839088 23973436 23993779 24042330 24180259 24232623 24406628 24413402 24731853 24928145 25416202 26171879 26491622 26707227 27450864 27501712 27674204 27676335 27696995 28028926 28260408 28401362 28525459 28775281 28878339 28903119 29273069 29403535 29755746 29781243 29938514 30085584 30202809 30254966 30264054 30272965 30331666 30809995 30964673 31241391 31372949 31635931 31665852 31695255 31987264 32230271 32347599 32459667

20566224 20865368 20973068 21239956 21366654 21488246 21504966 21594215 21618033 21624157 21723187 21723597 21833680 21840094 21870152 21901167 22054099 22132916 22556059 22592495 22621792 22755700 22821428 22905968 23184344 23478560 23731885 23731885 23731885 23731885 23747872 23747872 23747872 23747872 23747872 23838668 23839116 23973456 23993791 24042344 24180268 24232632 24406639 24413414 24731876 24928162 25416213 26171900 26491631 26707237 27450882 27501732 27674219 27676351 27697015 28028947 28260424 28401378 28525490 28775300 28878350 28903151 29273080 29403558 29755758 29781256 29938524 30085594 30202825 30254985 30264072 30272978 30331677 30810014 30964689 31241409 31372962 31635945 31665881 31695277 31987277 32230281 32347616 32459678

8 5 5.5 12 8 4.5 7.5 5.5 5 6 6.33333 5.25 6.66667 8.5 4.33333 4.25 3.75 6 11.5 6 3.4 7 6 6.5 5 5.5 7.66667 7.66667 7.66667 7.66667 6 6 6 6 6 6.5 9.66667 5.25 4.33333 3.75 5 5 6 6.5 6 4.5 3 3.66667 5 5.5 4.75 4.2 5.33333 8.5 10.5 5.5 5.66667 5.66667 8 4 6 8.25 4 6 6.5 7 5.5 5.5 8.5 4 9.5 7 6 4 8.5 4.75 3.5 3.75 7.5 5.75 4.66667 5.5 3.6 6

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000035974 CDH11 intron ENSSSCT00000033754 CDH11 intron ENSSSCT00000003095 CDH11 intron ENSSSCT00000033473 CDH11 intron ENSSSCT00000035974 CDH11 intron ENSSSCT00000033754 CDH11 intron ENSSSCT00000003095 CDH11 intron ENSSSCT00000033473 CDH11 intron ENSSSCT00000032635 CDH11 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000003062 SMPD3 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000003129 LPCAT2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000003136 TOX3 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000003145 PHKB intron ENSSSCT00000003145 PHKB intron . . intergenic

. -0.16 . 0.222 -0.249 . -0.279 0.509 0.093 0.155 0.047 . 0.053 . -0.21 0.007 0.091 -0.192 0.313 -0.002 -0.114 -0.092 0.281 0.729 0.513 -0.185 -0.033 -0.033 -0.033 -0.033 -0.26 -0.26 -0.26 -0.26 -0.26 0.097 -0.191 -0.06 -0.054 0.246 0.535 -0.095 0.072 0.073 0.098 -0.005 . 0.169 . 0.263 -0.071 -0.217 0.503 0.658 0.272 0.018 1.366 1.221 -0.121 0.047 0.149 -0.145 . -0.18 -0.189 0.113 -0.25 . 0.065 0.083 1.231 0.021 0.004 . 0.093 -0.125 -0.214 . . -0.027 -0.022 0.317 . 0.277

rs789497309 rs790471246 rs786609071 . 939505 rs7912 rs788960983 700475 rs7890 853340 rs7934 . rs791411398 189309 rs7938 520342 rs7887 . . 811581 rs7933 rs790516338 rs792824711 rs793604302 rs793820021 301225 rs7872 rs790262664 668226 rs7894 rs789401165 595789 rs7927 . 667669 rs7928 . . . . . . . . . 063017 rs7927 rs790535487 833689 rs7862 rs792457477 . rs792971688 . rs791963968 rs792178891 305410 rs7896 rs790739864 rs786443610 rs789498524 . rs787237475 rs791477237 rs787050448 240471 rs7905 403568 rs7921 186332 rs7877 rs786872448 . rs788920971 353611 rs7893 . rs791418990 508521 rs7871 726750 rs7916 . rs787467010 rs787826106 rs789889385 . rs786701782 rs788829139 . rs789844702 690848 rs7883 rs793492673 335663 rs7888 rs788439298 rs788453390 rs788227585 198211 rs7888 445711 rs7883 rs790433018 rs790108291 rs791989465 rs792166104

2 2 3 2 2 2 3 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 4 4 2 3 2 2 2 2 2 2 2 2 4 2 2

AAAC.GTTT AGAGG.CCTCT AAAC.GTTT AAC.GTT AAAT.ATTT AAAC.GTTT AAAG.CTTT AAC.GTT AAT.ATT AAAC.GTTT AAAC.GTTT AT.AT ACAT.ATGT AC.GT AAAAAC.GTTTTT AT.AT AT.AT AAAC.GTTT AC.GT AAT.ATT AC.GT AC.GT AT.AT AC.GT AG.CT AC.GT AC.GT AC.GT AAG.CTT AG.CT AAAC.GTTT ACAT.ATGT AG.CT AGG.CCT AAAAT.ATTTT AC.GT AC.GT AAC.GTT AAAC.GTTT AAAC.GTTT AC.GT AAAAC.GTTTT AAAC.GTTT AAAAT.ATTTT AT.AT AAAC.GTTT AC.GT AAAC.GTTT AAAAAT.ATTTTT AC.GT AC.GT AAAG.CTTT AAAT.ATTT AAC.GTT AAAAT.ATTTT AAT.ATT AAAAAC.GTTTTT AAAAAC.GTTTTT AAAC.GTTT AAAT.ATTT AAAC.GTTT AG.CT AC.GT AC.GT AAAC.GTTT AG.CT AC.GT AAT.ATT AAAC.GTTT AC.GT AT.AT AAAC.GTTT AAC.GTT AAAC.GTTT AC.GT AAAC.GTTT AT.AT AAAAC.GTTTT AAAAC.GTTTT AT.AT AAT.ATT AC.GT AC.GT AAAAT.ATTTT

6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6

32685355 32727017 32816287 32899066 32950733 33302901 33338749 33709343 33809784 34262759 34442993 34500560 34844453 34934289 35030574 35273611 35274702 35499672 35560955 35597340 36034652 36034652 36090836 36126944 36507229 36577793 36602247 36943987 36984349 37173933 37328119 37365233 37625256 37702857 37904687 37917202 37928379 37981850 38120278 38120278 38422325 39122749 39239710 39713751 39721897 40712254 40861068 40978346 41035593 41053266 41123837 41133765 41178688 41199282 41291053 41297238 41310825 41336715 41711908 41915086 42070101 42941955 43427740 43489063 43930510 44532553 45609003 46096117 46301565 46457368 46532109 47424545 47814455 48085464 48418445 48543802 48691019 48938652 48938652 49214831 49392294 49881368 50057739 50910777

32685370 32727037 32816314 32899082 32950751 33302923 33338772 33709361 33809808 34262775 34443015 34500574 34844475 34934299 35030596 35273623 35274713 35499689 35560987 35597361 36034669 36034669 36090846 36126968 36507256 36577821 36602266 36943998 36984369 37173943 37328143 37365244 37625266 37702870 37904707 37917226 37928389 37981861 38120290 38120290 38422336 39122777 39239722 39713773 39721906 40712266 40861080 40978362 41035615 41053282 41123849 41133783 41178711 41199301 41291087 41297255 41310852 41336742 41711922 41915106 42070115 42941964 43427750 43489073 43930528 44532569 45609016 46096136 46301583 46457380 46532118 47424572 47814466 48085484 48418472 48543823 48691029 48938672 48938672 49214842 49392306 49881383 50057749 50910798

4 4.2 7 5.66667 4.75 5.75 6 6.33333 8.33333 4.25 5.75 7.5 5.75 5.5 3.83333 6.5 6 4.5 16.5 7.33333 9 9 5.5 12.5 14 14.5 10 6 7 5.5 6.25 3 5.5 4.66667 4.2 12.5 5.5 4 3.25 3.25 6 5.8 3.25 4.6 5 3.25 6.5 4.25 3.83333 8.5 6.5 4.75 6 6.66667 7 6 4.66667 4.66667 3.75 5.25 3.75 5 5.5 5.5 4.75 8.5 7 6.66667 4.75 6.5 5 7 4 5.25 14 5.5 5.5 4.2 4.2 6 4.33333 8 5.5 4.4

. ENSSSCT00000030872 . ENSSSCT00000003148 . . . . . . . . ENSSSCT00000020081 . ENSSSCT00000003155 . . . . . ENSSSCT00000026089 ENSSSCT00000024971 . . . . . . . . . . . . ENSSSCT00000025063 ENSSSCT00000025063 . . ENSSSCT00000003160 ENSSSCT00000027536 . . ENSSSCT00000021685 . . ENSSSCT00000003224 ENSSSCT00000003228 . . ENSSSCT00000003238 . . ENSSSCT00000003245 ENSSSCT00000003241 . . . . ENSSSCT00000022792 ENSSSCT00000003259 . ENSSSCT00000003285 ENSSSCT00000003296 . . . ENSSSCT00000003371 . ENSSSCT00000003398 . . ENSSSCT00000003432 . . ENSSSCT00000003452 . . ENSSSCT00000022965 ENSSSCT00000024758 ENSSSCT00000003469 ENSSSCT00000024369 ENSSSCT00000003479 . ENSSSCT00000026507

. intergenic . intron . intergenic GPT2 intron . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic U6 promoter . intergenic POP4 intron . intergenic . intergenic . intergenic . intergenic . intergenic ZNF536 intron ZNF536 intron . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic DPY19L3 intron DPY19L3 intron . intergenic . intergenic ANKRD27 intron SLC7A9 intron . intergenic . intergenic U6 promoter . intergenic . intergenic TYROBP intron WDR62 intron . intergenic . intergenic ZNF565 intron . intergenic . intergenic ZNF567 intron ZNF461 intron . intergenic . intergenic . intergenic . intergenic ZNF383 3'utr . intron . intergenic RYR1 intron . intron . intergenic . intergenic . intergenic GSK3A intron . intergenic CADM4 intron . intergenic . intergenic SYMPK intron . intergenic . intergenic . intron . intergenic . intergenic GLTSCR1 intron GLTSCR1 intron LIG1 intron EMP3 promoter HSD17B14 intron . intergenic . intron

-0.298 . . -0.177 0.146 . . . . -0.296 0.138 . . -0.031 -0.099 . . . -0.615 -0.153 . . -0.124 -0.231 1.227 -0.341 0.006 0.286 -0.101 -0.03 -0.094 . 0.032 0.1 0.108 -0.043 0.351 . -0.064 -0.064 . 0.298 . . . 0.369 0.376 . . . . . . 0.259 . . 0.34 . 0.294 0.1 . 0.522 . . . . 0.045 . -0.185 -0.364 . . . 0.302 0.359 -0.072 0.095 -0.127 -0.127 -0.593 0.247 -0.375 -0.317 -0.119

rs788917956 rs787509508 rs791343785 rs793340720 rs786402809 rs793783039 rs792470813 rs787326876 rs791423199 063157 rs7905 rs792778222 rs789338429 rs790978426 rs786900842 rs793303126 rs792521501 rs788998404 rs787905383 . 893751 rs7934 rs786423523 rs786423523 289042 rs7931 rs792414955 rs786325930 rs793744013 rs708510675 480484 rs7900 rs712598239 . rs791769972 690415 rs7876 rs790856259 . rs791759180 rs788596417 rs791081247 . rs792893252 rs792893252 rs791224766 717506 rs7888 rs786655930 rs786721621 rs788329548 693549 rs7916 . 131190 rs7911 rs792075771 rs790278762 rs786837587 rs788159625 . 715081 rs7865 rs793711100 874988 rs7890 291429 rs7916 rs787248368 rs789944365 rs792679882 rs792871378 rs790396864 rs792255101 rs793303830 369937 rs7865 rs788377739 . 403545 rs7921 018658 rs7908 986882 rs7921 . 975746 rs7904 rs790740903 792502 rs7893 rs788199224 rs792263379 326770 rs7885 . . rs791240257 rs790136589 . . rs787935971

2 2 2 2 2 3 2 2 2 2 2 2 4 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 4 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 3 2 2 2 3 2 2 2 3 2 2 2 2 2 2 2 2 2

AAAT.ATTT AAAAT.ATTTT AAAC.GTTT AT.AT AC.GT AC.GT AAC.GTT AAC.GTT AAG.CTT AAAAC.GTTTT AAAC.GTTT AAAAAC.GTTTTT AAAT.ATTT AAAAAC.GTTTTT AAG.CTT AG.CT AAAC.GTTT AAAAC.GTTTT AC.GT AGG.CCT AAT.ATT AAC.GTT AC.GT AAC.GTT AC.GT AC.GT AAAC.GTTT AAG.CTT AG.CT AAAC.GTTT AATG.CATT AAAAC.GTTTT AAAAG.CTTTT AAC.GTT AAAC.GTTT AGAT.ATCT AAAC.GTTT AT.AT AC.GT AAAAAC.GTTTTT AAAT.ATTT AGG.CCT AAAAAG.CTTTTT AAGC.GCTT AAAAG.CTTTT AC.GT AC.GT AG.CT AGC.GCT AAAC.GTTT AAAAT.ATTTT AC.GT AG.CT AC.GT AC.GT AAC.GTT AAAC.GTTT AAAC.GTTT AAC.GTT AAAC.GTTT AAAAAC.GTTTTT AG.CT AAAT.ATTT AAC.GTT AAC.GTT AAAG.CTTT AAAG.CTTT ATC.GAT AC.GT ATCC.GGAT AC.GT AC.GT AC.GT AAAT.ATTT AC.GT AC.GT AT.AT AAAAT.ATTTT AC.GT AAAT.ATTT AC.GT AT.AT AAAC.GTTT AAAC.GTTT

6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6

51342053 51820343 52341065 53076559 53444891 53444891 54275357 54275357 56777388 56831282 57191369 57217947 57687847 58204361 58390673 59038847 59527365 60378044 60438922 61217006 61757978 62175743 62585113 62880331 63032121 63212581 63693957 63937289 64237099 64261409 64268130 64356773 64666429 64676126 64680847 65234004 65302543 65421909 65668318 65720732 65797477 65915248 67122315 67189830 67205496 67527601 67720322 67884087 67961863 68161014 68481139 68662022 68937185 68947439 68947439 69235687 69249126 69355022 69369825 69649411 69745258 70180744 70225076 70257380 70436814 70468951 70562896 70692860 70795566 71055621 72517021 72521624 72532189 72616127 72891534 72944253 73363786 73459761 73564810 74315245 74745550 74769648 74951866 74951866

51342074 51820362 52341086 53076568 53444908 53444908 54275382 54275382 56777400 56831313 57191384 57217974 57687868 58204387 58390686 59038864 59527383 60378064 60438946 61217020 61757989 62175755 62585127 62880347 63032134 63212595 63693983 63937303 64237110 64261429 64268154 64356799 64666452 64676145 64680865 65234022 65302571 65421920 65668329 65720753 65797491 65915261 67122338 67189846 67205518 67527613 67720332 67884103 67961875 68161033 68481157 68662035 68937195 68947449 68947449 69235699 69249140 69355048 69369840 69649437 69745276 70180758 70225090 70257402 70436833 70468969 70562912 70692876 70795576 71055636 72517060 72521635 72532203 72616162 72891544 72944262 73363799 73459782 73564820 74315271 74745563 74769658 74951898 74951898

5.5 4 5.5 5 9 9 8.66667 8.66667 4.33333 6.4 4 4.66667 5.5 4.5 4.66667 9 4.75 4.2 12.5 5 4 4.33333 7.5 5.66667 7 7.5 6.75 5 6 5.25 6.25 5.4 4.8 6.66667 4.75 4.75 7.25 6 6 3.66667 3.75 4.66667 4 4.25 4.6 6.5 5.5 8.5 4.33333 5 3.8 7 5.5 5.5 5.5 4.33333 3.75 6.75 5.33333 6.75 3.16667 7.5 3.75 7.66667 6.66667 4.75 4.25 5.66667 5.5 4 20 6 7.5 9 5.5 5 7 4.4 5.5 6.75 7 5.5 8.25 8.25

. ENSSSCT00000003595 ENSSSCT00000024905 ENSSSCT00000003618 ENSSSCT00000025769 ENSSSCT00000003632 ENSSSCT00000027366 ENSSSCT00000022455 . . . . ENSSSCT00000004425 . ENSSSCT00000032230 . . . . . ENSSSCT00000022446 ENSSSCT00000003747 . . ENSSSCT00000003756 . ENSSSCT00000003762 . . . . . ENSSSCT00000003777 ENSSSCT00000003778 ENSSSCT00000003778 ENSSSCT00000003786 ENSSSCT00000003786 . ENSSSCT00000003795 . ENSSSCT00000003807 ENSSSCT00000003811 . . . . . . . . . ENSSSCT00000003835 . ENSSSCT00000027709 ENSSSCT00000003836 ENSSSCT00000003850 ENSSSCT00000003850 ENSSSCT00000003851 ENSSSCT00000003851 . ENSSSCT00000032385 ENSSSCT00000033697 ENSSSCT00000003868 . . . . . . . . ENSSSCT00000003882 . . . ENSSSCT00000027632 . . . . . ENSSSCT00000003918 ENSSSCT00000003922 ENSSSCT00000003923

. SIGLEC5 ZNF615 CACNG6 TTYH1 TTYH1 PTPRH PTPRH . . . . RPS5 . PRKCZ . . . . . NPHP4 ACOT7 . . PARK7 . CA6 . . . . . DFFA PEX14 PEX14 FRAP1 FRAP1 . FBXO44 . CLCN6 PLOD1 . . . . . . . . . KAZN . . . DNAJC16 DNAJC16 FBLIM1 FBLIM1 . FBXO42 PADI1 PADI3 . . . . . . . . PLA2G2A . . . MUL1 . . . . . EPHB2 KDM1A KDM1A

intergenic intron intron intron promoter promoter 3'utr 3'utr intergenic intergenic intergenic intergenic intron intergenic intron intergenic intergenic intergenic intergenic intergenic promoter intron intergenic intergenic intron intergenic intron intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intergenic intron intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intron intron intron intron intron intron intergenic intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic promoter intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intron intron intron

-0.037 . . . -0.254 -0.254 . . . . . . . . 0.589 . -0.351 -0.138 -0.438 . 0.146 2.137 -0.228 1.555 -0.097 . . -0.138 0.073 -0.364 . . 0.028 . . 0.252 -0.289 -0.166 1.03 -0.184 . 0.593 -0.435 . 0.019 -0.043 0.069 -0.113 -0.144 -0.243 -0.189 -0.108 -0.089 0.144 0.144 0.088 0.068 0.031 -0.134 -0.202 . -0.028 -0.34 . . -0.142 -0.113 . -0.321 -0.005 -0.285 . . . . . 0.139 0.048 0.34 . 0.038 0.14 0.19 0.19

465339 rs7901 rs789240568 468852 rs7917 rs786245327 rs792523984 rs792523984 152174 rs7930 152174 rs7930 594179 rs7877 454002 rs7887 423232 rs7873 rs792988934 rs789579895 . 503139 rs7892 010098 rs7921 rs792343292 rs786434609 rs789225885 rs789853814 366787 rs7877 rs791830740 209403 rs7870 750129 rs7882 rs792452892 rs792742785 rs787611498 rs786589481 399055 rs7897 rs693783101 rs791020399 rs790040390 563189 rs7874 242410 rs7879 rs792072305 307507 rs7920 705137 rs7920 085311 rs7916 rs788152514 347842 rs7885 674469 rs7871 . rs787235387 rs791670240 104460 rs7863 837990 rs7931 rs788410417 rs790737057 rs789737082 rs793108665 969310 rs7867 rs793026612 rs787741408 rs791330954 rs791330954 rs791116949 854943 rs7879 . rs793253460 rs792605751 rs786206765 327662 rs7868 rs793205161 rs791376184 rs792305502 . rs788483300 216867 rs7864 855139 rs7918 . 599075 rs7926 760132 rs7932 rs787663704 . . . rs790221559 rs791024635 . 396046 rs7908 875504 rs7913 . . .

2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2

AT.AT AAAG.CTTT AAAAC.GTTTT AAC.GTT AATC.GATT AAAAC.GTTTT AT.AT AC.GT AAC.GTT AAAT.ATTT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AAG.CTT AAAAT.ATTTT AAC.GTT AG.CT AG.CT AC.GT AG.CT AC.GT AAAC.GTTT ATC.GAT ACAG.CTGT AAAC.GTTT AT.AT AAAT.ATTT AG.CT AC.GT AAC.GTT AG.CT AAAC.GTTT AG.CT AAAC.GTTT AG.CT AG.CT AAC.GTT AT.AT AC.GT AAC.GTT AC.GT AAAT.ATTT AATG.CATT AATG.CATT AC.GT AAC.GTT AG.CT AAGG.CCTT ACGC.GCGT AAAC.GTTT AAAC.GTTT AAAAAC.GTTTTT AAAC.GTTT AG.CT AAC.GTT AAGG.CCTT AAGG.CCTT AC.GT AAAT.ATTT AAAC.GTTT AAT.ATT AT.AT AAG.CTT AAGG.CCTT AC.GT AT.AT ACAT.ATGT ACAG.CTGT AAAC.GTTT AAT.ATT AC.GT AAC.GTT AAAT.ATTT AC.GT ACC.GGT AAAT.ATTT AAAAC.GTTTT AAAC.GTTT AGC.GCT AT.AT AC.GT AT.AT AG.CT AT.AT

6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6

75181348 75246258 76024485 76046290 76289081 76492714 76852789 77224880 78641723 79121036 79363880 79405416 79436575 79566125 79831189 80050145 80189534 80244065 80299679 80654265 80803136 80851264 80868176 81102839 81166754 81410131 81464364 81765987 81965995 82296547 83398055 83914060 84041740 84218659 84229308 84235814 84520363 84590312 84594503 84595567 85243563 85566350 85667662 85790353 85916422 86066088 86482335 86493115 86880370 87705616 87833173 88033711 88393728 88534538 88578863 88733652 88733652 88776350 88861388 88885661 88992216 89188918 89248346 89253488 89669154 89714997 89946646 90053044 90169848 90336968 90369620 90449308 90462578 90750532 90917060 90923932 91115487 91123398 91161535 91300157 91348549 91409909 91483293 91510196

75181359 75246283 76024504 76046303 76289109 76492748 76852799 77224895 78641737 79121053 79363901 79405430 79436604 79566140 79831212 80050173 80189546 80244076 80299691 80654289 80803147 80851287 80868207 81102856 81166776 81410149 81464377 81765999 81966007 82296570 83398070 83914086 84041749 84218675 84229319 84235843 84520374 84590339 84594517 84595586 85243573 85566376 85667687 85790382 85916432 86066099 86482349 86493137 86880384 87705638 87833205 88033737 88393739 88534563 88578884 88733684 88733684 88776359 88861413 88885683 88992238 89188928 89248359 89253499 89669164 89715008 89946665 90053065 90169862 90336987 90369632 90449324 90462595 90750546 90917071 90923943 91115507 91123436 91161555 91300171 91348565 91409925 91483307 91510213

6 6.5 4 4.66667 7.25 7 5.5 8 5 4.5 5.5 3.75 6 5.33333 4.8 9.66667 6.5 6 6.5 12.5 6 6 10.6667 4.5 5.75 9.5 3.5 6.5 6.5 8 8 6.75 5 4.25 6 15 4 14 7.5 6.66667 5.5 6.75 6.5 7.5 5.5 4 7.5 5.75 3.75 5.75 8.25 4.5 3 13 7.33333 8.25 8.25 5 6.5 5.75 7.66667 5.5 4.66667 3 5.5 6 5 5.5 3.75 6.66667 6.5 5.66667 4.5 7.5 4 3 4.2 9.75 7 7.5 8.5 8.5 7.5 9

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000024815 CATSPER4 intron ENSSSCT00000003975 EYA3 intron . . intergenic ENSSSCT00000028011 RCC1 intron ENSSSCT00000028704 TRNAU1AP intron ENSSSCT00000027861 TAF12 intron . . intergenic ENSSSCT00000003981 EPB41 intron ENSSSCT00000003985 PTPRU intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000003994 . intron ENSSSCT00000003999 . intron . . intergenic . . intergenic ENSSSCT00000004018 CSMD2 intron ENSSSCT00000004018 CSMD2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000020107 SNORD22 promoter ENSSSCT00000004032 . intron ENSSSCT00000004034 TRAPPC3 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000004050 MACF1 intron ENSSSCT00000004050 MACF1 intron ENSSSCT00000023745 HEYL intron ENSSSCT00000004058 NT5C1A intron ENSSSCT00000004061 . intron ENSSSCT00000004052 . intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000004066 RLF intron . . intergenic . . intergenic . . intergenic ENSSSCT00000032434 LDLRAD4 intron ENSSSCT00000004070 CEP192 intron . . intergenic ENSSSCT00000025318 PTPN2 intron ENSSSCT00000031445 CEP76 3'utr ENSSSCT00000028047 . intron . . intergenic . . intergenic ENSSSCT00000022557 IMPA2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

0.009 . -0.066 0.148 -0.216 . . 0.846 -0.02 0.229 . . 0.456 0.284 0.379 -0.084 0.281 . 0.042 -0.409 -0.337 . -0.101 -0.167 0.115 . . . -0.001 . 0.226 -0.225 -0.39 -0.02 0.114 -0.113 0.234 -0.243 0.259 -0.048 . . . . -0.094 . . -0.065 0.38 -0.176 0.096 -0.305 -0.021 -0.1 . . . 0.2 . 0.042 . 0.405 . . . 0.164 0.042 . . 0.324 . -0.3 . . -0.188 . -0.099 0.21 0.056 . -0.199 . -0.047 .

147140 rs7922 010664 rs7897 rs788885662 260569 rs7898 . rs788056522 rs792296769 . 466971 rs7902 rs786613414 . . . rs790470702 rs789483116 325341 rs7896 rs793454489 . 202682 rs7906 . rs790491132 rs787901763 545427 rs7910 rs792804670 980692 rs7895 rs792834598 . rs696422270 . rs787699537 . rs789731403 . rs787599556 rs786825269 . . 595408 rs7935 068243 rs7898 716384 rs7903 rs790742995 rs793150867 rs789380643 rs788592785 rs793504318 rs709217950 905550 rs7864 . rs789731793 894141 rs7912 711447 rs7063 rs787717609 rs789551531 rs707868325 rs788938716 rs789241405 rs789241405 . . rs787519975 rs786985793 rs789281296 . rs788450015 rs792851819 272173 rs7886 027349 rs7922 rs791469414 rs792229356 438459 rs7916 . 007338 rs7888 rs790882559 . rs789234056 rs793781486 rs789889511 054110 rs7899 . rs793292516 rs792634739 rs786349076 rs789877075 .

2 3 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 3 2 2 2 3 2 2 2 3 3 2 4 2 4 2 2 2 2 2 2 2 2 3 2 3 2 3 2 4 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2

ATGC.GCAT AAAC.GTTT AAAC.GTTT AT.AT AAAC.GTTT AC.GT AC.GT AC.GT AC.GT AATT.AATT AC.GT AAAG.CTTT AAGG.CCTT AAT.ATT AAG.CTT AT.AT AGAGC.GCTCT AC.GT AC.GT AAAC.GTTT AAAG.CTTT AT.AT AAAAG.CTTTT AC.GT AG.CT AAAC.GTTT AAAT.ATTT ACAG.CTGT AAAC.GTTT AC.GT AT.AT AAAC.GTTT AAC.GTT AG.CT AAAT.ATTT AAAC.GTTT AG.CT AAT.ATT AC.GT AAAAAC.GTTTTT AC.GT AAAT.ATTT AC.GT AAAAG.CTTTT AAAT.ATTT AAAC.GTTT AAAG.CTTT AAAT.ATTT AAAAC.GTTTT AG.CT AAAC.GTTT AT.AT AAAG.CTTT AT.AT AAAT.ATTT AT.AT AG.CT AT.AT AATCAT.ATGATT AG.CT AG.CT AAAC.GTTT AAAT.ATTT AAC.GTT AAC.GTT AG.CT AC.GT AAAT.ATTT AC.GT AC.GT AGG.CCT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AAG.CTT AAAAC.GTTTT AAAAC.GTTTT AAC.GTT AATG.CATT AAAG.CTTT AAAG.CTTT AAAAAT.ATTTTT AC.GT AAC.GTT

6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6

91824929 91866495 91866495 92105019 92346239 92409475 92409475 92545326 92647994 92726334 92798062 92936658 93048165 93156765 93233128 93338712 93442079 93686710 93770304 93798120 93811075 93960710 93961047 94215508 94242037 94259653 94752787 95003862 95027629 95069327 95280953 95330656 95548825 95581817 95590815 95703659 95726530 95764845 95770294 95949308 95981855 96114852 96135670 96205207 96333672 96335091 96369918 96763386 96951014 97273108 97279322 97456786 97459231 97587678 97624836 97917004 97963601 98146606 98207450 98216554 98407644 98513714 98691072 98729480 98729480 99118258 99370829 99392333 99713900 99753223 99841236 99892160 99907720 100179386 100330159 100572350 101065449 101276400 101311754 101474831 101474831 101761908 102448839 102688800

91824944 91866526 91866526 92105029 92346261 92409486 92409486 92545347 92648004 92726351 92798074 92936671 93048184 93156782 93233159 93338722 93442098 93686722 93770327 93798140 93811120 93960726 93961070 94215530 94242047 94259687 94752816 95003875 95027643 95069341 95280966 95330676 95548849 95581827 95590829 95703681 95726541 95764861 95770314 95949330 95981865 96114872 96135682 96205229 96333695 96335103 96369941 96763404 96951046 97273120 97279353 97456796 97459249 97587690 97624853 97917019 97963623 98146620 98207478 98216570 98407681 98513736 98691084 98729492 98729492 99118276 99370838 99392348 99713914 99753237 99841253 99892185 99907738 100179397 100330176 100572379 101065476 101276414 101311771 101474845 101474845 101761935 102448870 102688813

4 8 8 5.5 5.75 6 6 11 5.5 4.5 6.5 3.5 5 6 10.6667 5.5 4 6.5 12 5.25 11.5 8.5 4.8 11.5 5.5 8.75 7.5 3.5 3.75 7.5 7 5.25 8.33333 5.5 3.75 5.75 6 5.66667 10.5 3.83333 5.5 5.25 6.5 4.6 6 3.25 6 4.75 6.6 6.5 8 5.5 4.75 6.5 4.5 8 11.5 7.5 4.83333 8.5 19 5.75 3.25 4.33333 4.33333 9.5 5 4 7.5 7.5 6 5.2 4.75 3 6 6 5.6 5 4.5 3.75 3.75 4.66667 16 4.66667

ENSSSCT00000004076 ENSSSCT00000004076 ENSSSCT00000004078 ENSSSCT00000004080 . ENSSSCT00000024838 ENSSSCT00000004082 ENSSSCT00000032539 . . . . . . . . . ENSSSCT00000004084 ENSSSCT00000004084 ENSSSCT00000004084 ENSSSCT00000004084 . . . . . ENSSSCT00000004085 . . . . . . . . . . . . ENSSSCT00000026090 . . . ENSSSCT00000004088 . . . ENSSSCT00000004093 . . . . . . . . . . . . . . . ENSSSCT00000029907 ENSSSCT00000026467 ENSSSCT00000004098 ENSSSCT00000031178 ENSSSCT00000031178 . . . . . . . . ENSSSCT00000004107 ENSSSCT00000027989 ENSSSCT00000027989 ENSSSCT00000004108 ENSSSCT00000024191 ENSSSCT00000004111 . .

. . RALBP1 ANKRD12 . SOGA2 SOGA2 PTPRM . . . . . . . . . . . . . . . . . . EPB41L3 . . . . . . . . . . . . . . . . DLGAP1 . . . EMILIN2 . . . . . . . . . . . . . . . ROCK1 ROCK1 GREB1L ABHD3 ABHD3 . . . . . . . . ANKRD29 LAMA5 LAMA5 LAMA3 LAMA3 OSBPL1A . .

intron intron intron intron intergenic intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intron intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intergenic intergenic

. . . 0.153 -0.294 0.039 0.039 . -0.236 0.248 -0.321 . -0.216 -0.048 0.114 . . 0.161 . 0.24 -0.018 0.128 -0.066 . . . 0.106 . 0.082 0.123 -0.038 -0.049 . 0.395 0.374 0.169 -0.095 0.018 -0.043 . -0.046 -0.05 0.023 -0.004 0.115 0.036 . 0.02 0.114 . 0.124 0.169 0.039 0.392 . 0.036 0.045 . . . 0.182 0.06 0.085 . . 1.322 0.12 -0.087 -0.025 0.151 -0.059 0.185 . 0.269 . 0.268 . 0.883 -0.047 0.296 0.296 . -0.247 0.181

. rs790357696 rs790357696 rs786819720 rs789902594 rs793024293 rs793024293 rs793680660 rs787868324 rs792453311 rs793607780 rs789232014 rs790632050 . rs791217831 rs793836556 452437 rs7862 rs787325777 rs788671695 rs789337089 rs786648078 rs793283749 rs791636298 379603 rs7931 rs792396324 rs792230191 235586 rs7923 . rs786343557 rs793585110 rs698121647 rs791980852 rs791739252 rs787984489 rs791136620 rs790017056 rs793608192 rs792608869 014700 rs7884 rs790992061 . rs788158908 rs790830263 433453 rs7901 rs790903171 . rs790012071 rs790804525 rs787885696 rs792814004 rs790713716 rs789605420 rs793229611 114893 rs7900 459270 rs7918 rs787312908 828006 rs7908 rs792577476 . 333408 rs7869 rs790305658 rs791431644 . rs788861348 rs788861348 rs793214520 rs791097121 340113 rs7915 953298 rs7930 rs790996573 rs793423560 278432 rs7892 820684 rs7901 . 949485 rs7897 689515 rs7894 rs793879093 rs787272636 rs792169969 rs787087609 rs787087609 rs787961323 rs790852455 rs792907075

2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 3 2 2 4 2 2 2 2 2 2 2 2 2 4 2 2 2 2 4 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 3 3 2 2 2 2 3 2 2 2 5 2 2 3 3 3 2 2 2 2 3 2 2 2 2 3 2 2 2 2 2 2 2 2 2

AAAC.GTTT AG.CT AGAT.ATCT ACAT.ATGT AAAC.GTTT AAAG.CTTT AAG.CTT AAG.CTT AAATG.CATTT ACAG.CTGT AC.GT AAT.ATT AG.CT AAC.GTT ATC.GAT AAAC.GTTT AAC.GTT AAAC.GTTT AC.GT AC.GT AAAAC.GTTTT AT.AT AAC.GTT AAAAT.ATTTT AT.AT AAAC.GTTT AAAG.CTTT AAG.CTT AAAT.ATTT AAAAAC.GTTTTT AAAC.GTTT AAAAAC.GTTTTT AT.AT AAAG.CTTT AT.AT AAAC.GTTT AAAAAT.ATTTTT AG.CT ATC.GAT ATC.GAT AAAG.CTTT AAG.CTT AAC.GTT AAAC.GTTT AC.GT AC.GT AG.CT AC.GT AC.GT AAAG.CTTT AT.AT AG.CT AAC.GTT AATT.AATT AG.CT AAAAG.CTTTT AAAT.ATTT AC.GT AT.AT AAGAAT.ATTCTT AAAC.GTTT AATG.CATT AAT.ATT AT.AT AAAAC.GTTTT AAAC.GTTT AC.GT AAC.GTT AAC.GTT AG.CT AC.GT AAG.CTT AAC.GTT AAC.GTT AAC.GTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAAAC.GTTTTT AAAAAC.GTTTTT AAAAAC.GTTTTT AAAAAC.GTTTTT AT.AT AAAC.GTTT

6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6

102803028 103107758 103142644 103351557 103581198 103865559 104041430 104041430 104060176 104085672 104145577 104176575 104229534 104286693 104442774 104573351 104655294 104784712 104914361 105066561 105078096 105107875 105395736 105549021 105640998 105872967 105946705 105960121 106104799 106290475 106588586 107171014 107252641 107272613 107718266 107789642 107813933 107879950 108069907 108069907 108108674 108329397 108677144 108719840 108780110 109271928 109313877 109378643 109404717 109414711 109490855 109869261 109891020 109969561 110069313 110161544 110265457 110379116 110429503 110610900 110625449 110739891 110875153 111343381 111373463 111669339 111834913 111926286 111926286 112381167 112672333 112680039 112914578 112914578 112914578 112999990 112999990 112999990 113099188 113099188 113099188 113099188 113467378 113827528

102803048 103107767 103142680 103351576 103581218 103865571 104041449 104041449 104060204 104085699 104145587 104176588 104229565 104286709 104442789 104573375 104655310 104784737 104914371 105066571 105078111 105107885 105395748 105549035 105641008 105872989 105946725 105960151 106104823 106290497 106588630 107171038 107252653 107272638 107718285 107789660 107813950 107879960 108069918 108069918 108108696 108329416 108677157 108719864 108780119 109271946 109313902 109378653 109404755 109414728 109490866 109869271 109891039 109969574 110069324 110161559 110265471 110379129 110429526 110610926 110625468 110739912 110875164 111343400 111373484 111669358 111834928 111926303 111926303 112381178 112672347 112680063 112914591 112914591 112914591 113000008 113000008 113000008 113099210 113099210 113099210 113099210 113467393 113827543

5.25 5 9.25 5 5.25 3.25 6.66667 6.66667 5.8 7 5.5 4.66667 16 5.66667 5.33333 6.25 5.66667 6.5 5.5 5.5 3.2 5.5 4.33333 3 5.5 5.75 5.25 10.3333 6.25 3.83333 11.25 4.16667 6.5 6.5 10 4.75 3 5.5 4 4 5.75 6.66667 4.66667 6.25 5 9.5 13 5.5 19.5 4.5 6 5.5 6.66667 3.5 6 3.2 3.75 7 12 4.5 5 5.5 4 10 4.4 5 8 6 6 6 7.5 8.33333 4.66667 4.66667 4.66667 4.75 4.75 4.75 3.83333 3.83333 3.83333 3.83333 8 4

. . . . . ENSSSCT00000004118 ENSSSCT00000031750 ENSSSCT00000004119 ENSSSCT00000031750 ENSSSCT00000031750 . . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000022644 ENSSSCT00000025628 ENSSSCT00000029235 . . . ENSSSCT00000004132 ENSSSCT00000004131 ENSSSCT00000004133 ENSSSCT00000004133 . . . . . . . ENSSSCT00000004137 ENSSSCT00000004137 . . . . . ENSSSCT00000024859 . ENSSSCT00000004139 ENSSSCT00000004139 . ENSSSCT00000032735 ENSSSCT00000004144 ENSSSCT00000032735 . . . ENSSSCT00000025775 ENSSSCT00000023176 ENSSSCT00000029253 ENSSSCT00000025775 ENSSSCT00000023176 ENSSSCT00000029253 ENSSSCT00000004148 ENSSSCT00000029253 ENSSSCT00000025775 ENSSSCT00000023176 . .

. . . . . TAF4B KCTD1 KCTD1 KCTD1 KCTD1 . . . . . . . . . . . . . . . . . . . . . . . . . . . DSG1 DSG2 DSG2 . . . MEP1B GAREM KLHL14 KLHL14 . . . . . . . NOL4 NOL4 . . . . . . . MAPRE2 MAPRE2 . GALNT1 GALNT1 GALNT1 . . . FHOD3 FHOD3 FHOD3 FHOD3 FHOD3 FHOD3 . FHOD3 FHOD3 FHOD3 . .

intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intron intergenic intron intron intergenic intron intron intron intergenic intergenic intergenic intron intron intron intron intron intron intron intron intron intron intergenic intergenic

-0.203 . 0.07 -0.035 0.435 . 0.196 0.196 0.041 0.16 0.279 -0.128 -0.026 0.17 -0.008 . 0.099 0.116 -0.363 0.397 -0.008 -0.041 0.098 -0.128 0.301 -0.061 . -0.243 -0.03 0.019 . -0.195 0.007 -0.043 . . 0.165 0.166 . . 0.119 . 0.457 . . 0.019 0.227 0.114 0.093 0.037 0.193 0.324 . . . . . 0.068 . 0.078 0.1 0.073 0.156 0.017 -0.131 -0.011 . 0.192 0.192 . . . -0.083 -0.083 -0.083 0.288 0.288 0.288 . . . . . 0.053

. rs789241293 rs793662530 rs789593031 rs793574140 rs786345540 rs788335004 rs788335004 rs791388784 201709 rs7895 . rs792411908 rs790211676 rs789304561 316728 rs7902 867276 rs7925 . rs789714791 . rs787634463 rs793345289 rs786325269 rs786608093 rs790747339 rs787319550 rs692897045 rs789392710 rs789439090 rs792008058 rs790070338 490448 rs7922 rs791817575 rs789504308 rs710553298 rs789990337 573796 rs7868 rs790107538 rs792627134 rs788631469 rs788631469 . rs791186539 rs787290761 rs789927364 rs792259027 . rs786489059 rs792413376 762266 rs7862 799994 rs7915 rs788600737 rs787489345 rs791529422 . . 843877 rs7917 rs787482435 887969 rs7929 . rs793744491 rs786973913 rs793687712 933615 rs7896 rs789311392 rs791926970 rs788097862 810678 rs7878 rs788432256 rs788432256 . 275972 rs7876 . rs791525234 rs791525234 rs791525234 242740 rs7903 242740 rs7903 242740 rs7903 491830 rs7863 491830 rs7863 491830 rs7863 491830 rs7863 rs793355675 878239 rs7923

2 2 2 2 2 2 2 2 2 2 3 2 2 2 4 2 3 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 3 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 3 3 3 3 2 2

AAG.CTT AC.GT AC.GT AAAAAC.GTTTTT AT.AT AAT.ATT AG.CT AT.AT AT.AT AC.GT AAAT.ATTT ATC.GAT AT.AT AC.GT ATC.GAT AT.AT AC.GT AAT.ATT AG.CT AC.GT AAAT.ATTT AC.GT AAAAT.ATTTT AG.CT AC.GT AG.CT AC.GT AT.AT AT.AT AC.GT AAAC.GTTT AAC.GTT AAAC.GTTT AAAC.GTTT ATCC.GGAT AAC.GTT AC.GT AAAT.ATTT AAAT.ATTT AAT.ATT AT.AT AT.AT AAAC.GTTT AG.CT AAAGG.CCTTT AAAT.ATTT AC.GT AAAAG.CTTTT AG.CT AT.AT AC.GT AG.CT AAT.ATT AAC.GTT AC.GT AAAC.GTTT AT.AT AT.AT AAAC.GTTT AAAC.GTTT AG.CT AACAC.GTGTT AAAG.CTTT ATC.GAT AAAT.ATTT AAAT.ATTT AAC.GTT AAAAT.ATTTT AGGG.CCCT AAAGAG.CTCTTT AT.AT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAT.ATTT AG.CT AAG.CTT AAG.CTT AAG.CTT AAG.CTT AT.AT AT.AT AT.AT AT.AT

6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6

114137794 114172244 114286376 114469533 114481315 114712169 114995578 115250733 115398630 115628804 115660113 116028372 116177083 116248004 116265924 116272303 116433204 116561775 116668583 116820353 116853554 116963146 117148363 117373637 117450972 117565898 117746379 117797082 118011701 118109718 118311648 119184353 119456221 119689812 119697765 119713418 120307655 120372156 120484902 120695808 120816057 120926659 121179689 121181736 121297370 121395690 121460077 121630387 121936209 121968084 122283987 122756467 122838667 122847847 122925815 122928274 122945893 123162216 123249324 123293068 123325638 123563269 123689299 123700242 123902674 123920457 123999531 124006877 124141937 124247551 124351908 124406662 124633551 125136573 125176360 125232775 125620651 125620651 125620651 125620651 125648126 125648126 125648126 125648126

114137817 114172262 114286385 114469561 114481325 114712180 114995600 115250747 115398646 115628815 115660146 116028411 116177102 116248034 116265937 116272319 116433216 116561805 116668592 116820365 116853566 116963158 117148385 117373649 117450985 117565911 117746393 117797093 118011712 118109730 118311666 119184367 119456254 119689845 119697779 119713431 120307666 120372177 120484920 120695823 120816081 120926670 121179704 121181750 121297392 121395704 121460087 121630404 121936221 121968100 122283997 122756477 122838680 122847860 122925833 122928294 122945928 123162233 123249347 123293086 123325651 123563284 123689321 123700254 123902692 123920478 123999547 124006900 124141948 124247583 124351918 124406681 124633571 125136586 125176381 125232789 125620664 125620664 125620664 125620664 125648137 125648137 125648137 125648137

8 9.5 5 4.83333 5.5 4 11.5 7.5 8.5 6 8.5 13.3333 10 15.5 4.66667 8.5 6.5 10.3333 5 6.5 3.25 6.5 4.6 6.5 7 7 7.5 6 6 6.5 4.75 5 8.5 8.5 3.75 4.66667 6 5.5 4.75 5.33333 12.5 6 4 7.5 4.6 3.75 5.5 3.6 6.5 8.5 5.5 5.5 4.66667 4.66667 9.5 5.25 18 9 6 4.75 7 3.2 5.75 4.33333 4.75 5.5 5.66667 4.8 3 5.5 5.5 5 5.25 3.5 5.5 7.5 4.66667 4.66667 4.66667 4.66667 6 6 6 6

. . . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000004151 . . . . . . . . . . . . . . . . . . . . ENSSSCT00000004163 . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000029114 ENSSSCT00000004170 ENSSSCT00000004172 ENSSSCT00000025176 ENSSSCT00000029114 ENSSSCT00000004170 ENSSSCT00000004172 ENSSSCT00000025176

. . . . . . . . . . . . . . . . . . . . . . . . . . . . PIK3C3 . . . . . . . . . . . . . . . . . . . . LPHN2 . . . . . . . . . . . . . . . . . . . . . . . . . . NEXN NEXN FAM73A FAM73A NEXN NEXN FAM73A FAM73A

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intron intron

-0.186 -0.509 . . 0.088 0.045 -0.081 . -0.022 -0.435 . 0.139 -0.011 -0.001 . -0.039 0.306 -0.066 -0.126 -0.016 . -0.226 -0.09 0.004 . 0.318 -0.089 0.887 0.515 . . . 0.115 0.258 -0.05 0.153 0.215 0.217 0.015 -0.046 1.66 -0.012 -0.189 -0.059 -0.222 0.197 -0.075 -0.006 -0.052 0.275 0.595 0.394 -0.088 0.53 -0.071 -0.029 -0.276 -0.146 . . 0.017 . -0.09 0.61 0.626 -0.149 . -0.072 -0.204 -0.107 -0.093 1.61 . 0.56 0.015 . . . . . 0.173 0.173 0.173 0.173

. 344421 rs7932 . rs790592644 rs792776424 . . . rs791048840 rs790904949 rs792684981 . rs788985486 . rs787392286 rs793493824 rs788011604 . rs788494159 . . . rs787214380 rs786703456 rs709573832 rs789172462 905384 rs7931 rs791722278 . . 265494 rs7914 rs787789676 103828 rs7916 rs788122143 . 301154 rs7867 rs788693706 rs791866251 885635 rs7930 775695 rs7870 719325 rs7931 rs787173094 rs789649388 . rs789253107 . rs196960707 rs790656416 rs786503376 rs786596200 rs791373771 . rs790214030 rs792026947 483029 rs7934 rs787088260 rs787173080 rs789152730 rs787244759 . rs787698180 662557 rs7890 067552 rs7881 rs786848753 . rs704502297 371445 rs7869 720572 rs7902 . rs789311194 . 098734 rs7863 rs792153091 541467 rs7873 rs786540515 953163 rs7865 911553 rs7894 911553 rs7894 911553 rs7894 911553 rs7894 rs787010838 rs787010838 rs787010838 rs787010838

2 3 2 2 2 2 3 2 2 2 2 2 2 2 2 2 3 2 2 2 2 3 2 2 4 2 3 2 2 4 2 2 4 2 2 2 4 2 2 2 2 2 2 2 2 2 3 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 4 2 2 2 3 2 3 3 3 3 2 2 2 2

AG.CT AAG.CTT AC.GT AATC.GATT AAG.CTT AT.AT AAAAC.GTTTT AC.GT AAAAG.CTTTT AAAAG.CTTTT AG.CT AG.CT AAAC.GTTT AT.AT AG.CT AT.AT AC.GT AAAC.GTTT AT.AT AC.GT AT.AT AT.AT AC.GT AT.AT AC.GT AT.AT AC.GT ACAT.ATGT AAAC.GTTT AGAT.ATCT AC.GT AG.CT AG.CT AAAAT.ATTTT AAAC.GTTT AAAAC.GTTTT AG.CT AC.GT AC.GT AC.GT AT.AT AAT.ATT AATG.CATT AAG.CTT ATC.GAT AAAC.GTTT AC.GT AT.AT AAAC.GTTT AAC.GTT AAAG.CTTT AATG.CATT AC.GT AAAC.GTTT AT.AT ACAC.GTGT AC.GT AAAAT.ATTTT AT.AT AC.GT AAAT.ATTT AT.AT AAAG.CTTT AAAT.ATTT AC.GT AC.GT AAAT.ATTT AC.GT AC.GT AC.GT AC.GT AC.GT AG.CT AG.CT AG.CT AG.CT AG.CT AG.CT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT

6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6

125833662 125854388 126219697 126507518 126763776 126873691 127202831 127284905 127395502 127395502 127452830 127452830 127713981 128088640 128244659 128306895 128487208 128608064 128831613 128902905 129130342 129141336 129157701 129194506 129549587 129550461 129582715 129790977 129855302 129947662 130012569 130101661 130206726 130446558 130451897 130464637 130545694 130773803 130778001 130785012 130811514 131317625 131345936 131671832 131921232 131948668 132032014 132086337 132209283 132368858 132535235 132613430 132619192 132910681 133154288 133185266 133200140 133224407 133224931 133337118 133351039 133486113 133630589 133728862 133809778 133824447 133943197 134140234 134140234 134140234 134140234 134140234 134150180 134150180 134150180 134150180 134150180 134164945 134235667 134235667 134235667 134235667 134235667 134235667

125833676 7.5 . . intergenic 125854408 7 . . intergenic 126219715 9.5 ENSSSCT00000004175 AK5 intron 126507543 6.5 . . intergenic 126763790 5 . . intergenic 126873701 5.5 . . intergenic 127202861 6.2 . . intergenic 127284917 6.5 . . intergenic 127395525 4.8 ENSSSCT00000023892 MSH4 intron 127395525 4.8 ENSSSCT00000004176 MSH4 intron 127452841 6 ENSSSCT00000023892 MSH4 intron 127452841 6 ENSSSCT00000004176 MSH4 intron 127713993 3.25 ENSSSCT00000004180 SLC44A5 intron 128088649 5 . . intergenic 128244671 6.5 . . intergenic 128306906 6 ENSSSCT00000004183 CRYZ intron 128487229 11 . . intergenic 128608095 8 . . intergenic 128831624 6 . . intergenic 128902921 8.5 . . intergenic 129130353 6 . . intergenic 129141347 6 . . intergenic 129157715 7.5 . . intergenic 129194516 5.5 . . intergenic 129549601 7.5 . . intergenic 129550472 6 . . intergenic 129582727 6.5 . . intergenic 129791003 6.75 . . intergenic 129855324 5.75 . . intergenic 129947682 5.25 . . intergenic 130012580 6 . . intergenic 130101672 6 . . intergenic 130206747 11 . . intergenic 130446577 4 . . intergenic 130451909 3.25 . . intergenic 130464655 3.8 . . intergenic 130545706 6.5 . . intergenic 130773813 5.5 ENSSSCT00000031624 NEGR1 intron 130778014 7 ENSSSCT00000031624 NEGR1 intron 130785036 12.5 ENSSSCT00000031624 NEGR1 intron 130811532 9.5 ENSSSCT00000031624 NEGR1 intron 131317639 5 . . intergenic 131345958 5.75 . . intergenic 131671857 8.66667 . . intergenic 131921266 11.6667 . . intergenic 131948688 5.25 . . intergenic 132032028 7.5 ENSSSCT00000004193 CTH intron 132086352 8 ENSSSCT00000004194 ANKRD13C intron 132209302 5 ENSSSCT00000004195 SFRS11 intron 132368877 6.66667 ENSSSCT00000004197 LRRC7 intron 132535257 5.75 . . intergenic 132613452 5.75 ENSSSCT00000027842 . promoter 132619217 13 . . intergenic 132910705 6.25 . . intergenic 133154299 6 . . intergenic 133185290 6.25 . . intergenic 133200149 5 . . intergenic 133224431 5 . . intergenic 133224940 5 . . intergenic 133337138 10.5 . . intergenic 133351052 3.5 . . intergenic 133486123 5.5 . . intergenic 133630612 6 . . intergenic 133728880 4.75 . . intergenic 133809791 7 ENSSSCT00000004200 GPR177 intron 133824456 5 . . intergenic 133943212 4 . . intergenic 134140250 8.5 ENSSSCT00000032706 IL12RB2 intron 134140250 8.5 ENSSSCT00000004204 IL12RB2 intron 134140250 8.5 ENSSSCT00000036495 IL12RB2 intron 134140250 8.5 ENSSSCT00000032636 IL12RB2 intron 134140250 8.5 ENSSSCT00000032700 IL12RB2 intron 134150193 7 ENSSSCT00000032706 IL12RB2 intron 134150193 7 ENSSSCT00000004204 IL12RB2 intron 134150193 7 ENSSSCT00000036495 IL12RB2 intron 134150193 7 ENSSSCT00000032636 IL12RB2 intron 134150193 7 ENSSSCT00000032700 IL12RB2 intron 134164954 5 . . intergenic 134235682 4 ENSSSCT00000033328 IL23R intron 134235682 4 ENSSSCT00000033223 IL23R intron 134235682 4 ENSSSCT00000034103 IL23R intron 134235682 4 ENSSSCT00000032983 IL23R intron 134235682 4 ENSSSCT00000004206 IL23R intron 134235682 4 ENSSSCT00000032866 IL23R intron

. 0.078 0.065 0.142 0 -0.016 0.163 -0.091 . . . . 0.146 0.329 0.047 0.153 -0.053 -0.006 . . . . 0.04 -0.13 -0.125 0.318 -0.059 0.27 -0.157 . -0.093 0.199 . -0.055 -0.31 0.112 0.05 -0.158 -0.086 0.069 . 0.107 0.059 -0.112 0.132 . -0.018 0.311 1.993 . 0.229 -0.053 -0.155 . . 0.149 0.404 . . . . 0.001 0.573 0.052 0.229 -0.072 . 0.204 0.204 0.204 0.204 0.204 1.313 1.313 1.313 1.313 1.313 0.065 0.07 0.07 0.07 0.07 0.07 0.07

rs787958920 784921 rs7934 rs788921795 622667 rs7876 . rs787206463 135716 rs7921 . 981646 rs7885 981646 rs7885 . . rs790709400 . rs789479310 968677 rs7899 rs790104646 rs791889768 rs791830249 rs791307121 rs792164700 604066 rs7919 . rs791577059 rs789954303 . rs693594986 227482 rs7931 rs196948674 472668 rs7931 rs790799676 494423 rs7919 626037 rs7925 rs793147530 254252 rs7870 . rs786335034 rs787914706 219528 rs7862 508948 rs7926 rs792580596 674244 rs7908 rs792508496 rs786671145 . 355485 rs7883 . 436296 rs7911 446003 rs7906 023086 rs7913 830635 rs7921 538771 rs7883 642440 rs7923 rs793236703 053235 rs7880 . rs786793343 rs791362212 rs787928544 rs695544273 rs793836119 874650 rs7891 . rs791466090 rs788661799 . rs792150133 rs787793444 rs787793444 rs787793444 rs787793444 rs787793444 386634 rs7898 386634 rs7898 386634 rs7898 386634 rs7898 386634 rs7898 . 084541 rs7865 084541 rs7865 084541 rs7865 084541 rs7865 084541 rs7865 084541 rs7865

3 2 4 2 3 2 2 4 2 2 3 3 2 2 2 2 2 2 2 4 2 2 2 2 2 2 4 2 2 2 2 2 3 2 2 2 2 2 2 2 2 3 2 2 2 2 4 2 2 2 2 2 5 3 2 2 2 2 2 3 2 2 3 2 2 2 2 5 5 5 5 5 2 2 2 2 2 2 2 2 2 2 2 2

AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAT.ATTT AATG.CATT AAAC.GTTT AT.AT AAAAT.ATTTT AAAAAC.GTTTTT ATC.GAT AC.GT AAAAC.GTTTT AAC.GTT AAAC.GTTT AC.GT AC.GT ACC.GGT AG.CT AAAC.GTTT AAC.GTT AAAAAC.GTTTTT AATT.AATT AG.CT AC.GT AGAT.ATCT AAT.ATT AAAAC.GTTTT AAT.ATT AATG.CATT AAAAC.GTTTT AAAC.GTTT AAAAC.GTTTT AAAT.ATTT AATC.GATT AG.CT AAAT.ATTT AAAC.GTTT AAT.ATT AC.GT AC.GT AT.AT AC.GT AC.GT AAAT.ATTT AAAAT.ATTTT AT.AT AC.GT AT.AT AAAG.CTTT AG.CT AC.GT AG.CT AT.AT AAAT.ATTT AAAC.GTTT AC.GT AAT.ATT AAC.GTT AC.GT AAAT.ATTT AG.CT AC.GT AT.AT AG.CT AAAT.ATTT AAAAC.GTTTT AC.GT AT.AT AAAAC.GTTTT AC.GT AT.AT AT.AT AAAT.ATTT ATCC.GGAT AC.GT AAAC.GTTT AT.AT AAAC.GTTT AATG.CATT AAAG.CTTT AAAC.GTTT AAAG.CTTT

6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6

134235667 134235667 134235667 134235667 134235667 134306042 134310908 134389459 134435595 134440377 134766536 134842114 134850229 134861122 134885599 134898718 135120122 135331792 135393235 135442826 135675406 135768458 135886391 136154207 136195495 136218927 136233518 136327478 136575569 136753075 137037447 137139578 137140255 137183923 137199645 137217631 137562328 137586950 137633844 137637185 137676351 138036359 138390729 138653593 138702228 138747991 139283186 139492027 139499566 139532666 139727183 139774942 140083539 140150906 140154043 140378413 140445960 140465145 140581475 140581753 140634331 140668271 140734754 140767849 140784833 140954432 140969179 141030491 141040781 141047426 141281208 141402348 141410080 141419993 141620967 141779841 141917400 142008740 142009793 142035255 142144489 142341162 142375480 142472804

134235682 134235682 134235682 134235682 134235682 134306054 134310934 134389478 134435613 134440391 134766558 134842128 134850242 134861142 134885617 134898733 135120133 135331803 135393247 135442836 135675439 135768474 135886409 136154219 136195505 136218936 136233555 136327493 136575589 136753091 137037469 137139598 137140270 137183941 137199667 137217655 137562337 137586966 137633862 137637197 137676363 138036369 138390750 138653607 138702243 138748009 139283202 139492036 139499576 139532675 139727195 139774956 140083548 140150934 140154053 140378434 140445978 140465162 140581488 140581770 140634345 140668293 140734764 140767859 140784843 140954443 140969201 141030519 141040804 141047452 141281233 141402362 141410089 141420010 141620978 141779861 141917424 142008758 142009802 142035280 142144502 142341188 142375498 142472820

4 4 4 4 4 3.25 6.75 5 9.5 3 3.83333 5 7 4.2 6.33333 4 6 6 4.33333 5.5 8.5 5.66667 3.16667 3.25 5.5 5 9.5 5.33333 4.2 5.66667 5.75 4.2 4 3.8 5.75 6.25 5 4.25 4.75 4.33333 6.5 5.5 11 7.5 8 4.75 3.4 5 5.5 5 3.25 7.5 5 14.5 5.5 5.5 4.75 9 4.66667 6 7.5 5.75 5.5 5.5 5.5 6 5.75 5.8 12 13.5 5.2 7.5 5 9 3 5.25 12.5 4.75 5 6.5 3.5 6.75 4.75 4.25

ENSSSCT00000034401 ENSSSCT00000034079 ENSSSCT00000033490 ENSSSCT00000036227 ENSSSCT00000033623 . . . ENSSSCT00000004208 ENSSSCT00000004208 . . . . ENSSSCT00000004211 ENSSSCT00000004211 . . . ENSSSCT00000004213 . . . ENSSSCT00000005331 . . . . . ENSSSCT00000004217 . . . ENSSSCT00000004219 ENSSSCT00000004219 ENSSSCT00000004219 . . . . . . . . . . . . . . ENSSSCT00000004232 . . ENSSSCT00000004235 ENSSSCT00000004235 ENSSSCT00000004236 ENSSSCT00000004237 ENSSSCT00000004237 ENSSSCT00000004237 ENSSSCT00000004237 ENSSSCT00000004237 ENSSSCT00000004237 . . . . . . . . . . . . . . . . . . . . . .

IL23R IL23R IL23R IL23R IL23R . . . C1orf141 C1orf141 . . . . PDE4B PDE4B . . . DNAJC6 . . . CACHD1 . . . . . UBE2U . . . PGM1 PGM1 PGM1 . . . . . . . . . . . . . . C1orf87 . . HOOK1 HOOK1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

intron intron intron intron intron intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intron intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intron intron intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

0.07 0.07 0.07 0.07 0.07 0.288 0.026 . 0.023 0.455 . -0.026 -0.016 -0.021 0.126 -0.021 0.069 0.244 0.087 0.059 . 0.023 -0.036 0.132 1.01 1.522 0.093 0.006 . . -0.137 -0.034 -0.097 0.409 0.125 0.106 -0.018 0.27 -0.236 0.155 -0.001 0.284 0.132 . . -0.094 0.445 -0.26 -0.006 0.051 0.062 0.21 0.166 0.004 0.049 -0.109 . 0.859 0.12 0.401 0.047 0.371 0.077 -0.044 0.063 -0.04 0.052 -0.008 -0.062 -0.208 . -0.024 0.171 0.015 -0.018 0.069 -0.13 -0.156 -0.131 . . 0.862 0.053 -0.08

084541 rs7865 084541 rs7865 084541 rs7865 084541 rs7865 084541 rs7865 . 613993 rs7908 rs788894222 . 078815 rs7864 rs789857878 849583 rs7888 . 970362 rs7916 rs787441868 . 495692 rs7886 rs789576686 . rs788745474 rs791352230 rs791536133 247345 rs7924 rs791580540 rs788096544 rs786924098 rs787076610 rs787683874 rs793598614 833671 rs7905 rs792540804 rs791166823 619172 rs7870 rs790439394 rs786680584 rs789229786 rs786269567 rs790536339 368083 rs7903 . rs787281539 . rs692133926 rs788613161 rs790685471 rs786232921 rs786481231 . . rs787739405 . rs791907947 rs693119419 277782 rs7882 rs793232280 132703 rs7910 rs786730869 604930 rs7880 rs792122379 827766 rs7904 rs786990090 623881 rs7899 rs791375823 rs790364801 rs791400936 rs789777148 487832 rs7901 rs790987255 764959 rs7917 177467 rs7898 583807 rs7894 142328 rs7862 . 136173 rs7867 . rs788435093 rs789968649 984148 rs7870 rs789996030 rs694109612 . 604514 rs7930 521184 rs7912 rs786231613

2 2 2 2 2 2 2 3 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 3 2 2 3 3 2 2 2 4 2 3 2 2 2 2 2 3 2 2 2 4 2 2 2 2 2 2 2 3 3 2 2 3 3 2 2 2 3 2 2 3 2 3 2 2 2 2 3

AAC.GTT AAAATT.AATTTT AATG.CATT AG.CT AT.AT AGC.GCT AC.GT AAAT.ATTT AG.CT AAAT.ATTT AAT.ATT AT.AT AGGGG.CCCCT AAAAC.GTTTT AAACC.GGTTT AT.AT AAAGGG.CCCTT AG.CT AG.CT AAAC.GTTT AC.GT AG.CT AAAC.GTTT AG.CT AAAC.GTTT AAGT.ACTT AT.AT AC.GT AAAC.GTTT AAAT.ATTT AATG.CATT AAAAG.CTTTT AAAAG.CTTTT AAC.GTT AAAG.CTTT AAAAG.CTTTT AAT.ATT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AC.GT AC.GT AAC.GTT AC.GT AAAC.GTTT AAAAAC.GTTTTT AG.CT AAAC.GTTT AAAAC.GTTTT AAC.GTT AC.GT AC.GT AT.AT AT.AT AAAAC.GTTTT AAAC.GTTT ACC.GGT AGAGGG.CCCTC AC.GT AAAC.GTTT AG.CT AAT.ATT AAAT.ATTT AC.GT AAC.GTT AG.CT AC.GT AAAAAC.GTTTTT AAG.CTT AAAG.CTTT AAAG.CTTT AG.CT AAAAAC.GTTTTT AAC.GTT AAAC.GTTT AAAAC.GTTTT AAG.CTT AAAC.GTTT AT.AT AG.CT AAAG.CTTT

6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6

142542993 142558671 142583058 142626182 142677805 142945594 143743220 143916331 144391436 144410114 144807787 144823953 144910090 144994457 145082498 145082619 145507517 145529899 145534905 145587237 145864768 145906813 145948419 145980546 146486778 146522472 146561038 146586050 146847237 147008791 147169333 147330356 147330356 147582148 147647936 147766683 147775653 147923005 147923005 147939775 147939775 147941896 147941896 147943562 147943562 148033456 148162535 148167922 148171730 148236263 148383981 148648207 148873736 149030963 149030963 149222188 149222188 149817096 149821961 150015219 150275344 150417271 150543481 150794812 150969175 151062685 151332132 151402929 151705282 151707249 151760713 151854462 151973399 151973399 152794076 152795203 153031251 153164183 153362411 153532416 153672127 153857564 153870834 154002722

142543031 142558691 142583075 142626193 142677825 142945608 143743231 143916349 144391446 144410128 144807804 144823980 144910106 144994485 145082515 145082644 145507553 145529913 145534917 145587251 145864780 145906824 145948433 145980558 146486801 146522486 146561056 146586064 146847259 147008806 147169355 147330385 147330385 147582163 147647961 147766703 147775676 147923027 147923027 147939793 147939793 147941910 147941910 147943571 147943571 148033477 148162565 148167948 148171753 148236273 148383995 148648221 148873752 149030975 149030975 149222197 149222197 149817120 149821979 150015235 150275371 150417283 150543500 150794831 150969196 151062704 151332147 151402941 151705291 151707259 151760730 151854476 151973425 151973425 152794085 152795232 153031264 153164203 153362433 153532429 153672145 153857574 153870850 154002734

13 3.5 4.5 6 10.5 5 6 4.75 5.5 3.75 6 14 3.4 5.8 3.6 13 6.16667 7.5 6.5 3.75 6.5 6 3.75 6.5 6 3.75 9.5 7.5 5.75 4 5.75 6 6 5.33333 6.5 4.2 8 5.75 5.75 4.75 4.75 3.75 3.75 5 5 7.33333 15.5 6.75 4 5.5 3.75 3 5.66667 6.5 6.5 5 5 5 4.75 5.66667 4.66667 6.5 5 10 7.33333 5 8 4.33333 5 5.5 3 5 6.75 6.75 5 5 4.66667 5.25 4.6 4.66667 4.75 5.5 8.5 3.25

. . . . . . . . . . . . . . . . ENSSSCT00000027891 . . . ENSSSCT00000031990 . ENSSSCT00000029087 . . . . ENSSSCT00000004260 ENSSSCT00000004264 ENSSSCT00000004265 ENSSSCT00000004269 ENSSSCT00000029203 ENSSSCT00000004271 ENSSSCT00000004275 ENSSSCT00000004275 . . ENSSSCT00000028423 ENSSSCT00000026725 ENSSSCT00000028423 ENSSSCT00000026725 ENSSSCT00000028423 ENSSSCT00000026725 ENSSSCT00000026725 ENSSSCT00000028423 ENSSSCT00000004282 ENSSSCT00000028073 ENSSSCT00000028073 ENSSSCT00000028073 ENSSSCT00000028073 . . . ENSSSCT00000004289 ENSSSCT00000036500 ENSSSCT00000004289 ENSSSCT00000036500 . . . . . . . . . . . . . ENSSSCT00000004299 . ENSSSCT00000024887 ENSSSCT00000022260 . . . . ENSSSCT00000004332 . . ENSSSCT00000022870 ENSSSCT00000022870 ENSSSCT00000030222

. . . . . . . . . . . . . . . . TMEM61 . . . LRRC42 . TCEANC2 . . . . APOER2 SLC1A7 SCP2 . ZCCHC11 ZCCHC11 ZFYVE9 ZFYVE9 . . RAB3B RAB3B RAB3B RAB3B RAB3B RAB3B RAB3B RAB3B NRD1 OSBPL9 OSBPL9 OSBPL9 OSBPL9 . . . FAF1 FAF1 FAF1 FAF1 . . . . . . . . . . . . . . . . CYP4X1 . . . . TESK2 . . EIF2B3 EIF2B3 TMEM53

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intron intergenic intron intergenic intergenic intergenic intergenic intron intron intron intron intron intron intron intron intergenic intergenic intron intron intron intron intron intron intron intron intron intron intron intron intron intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic promoter intergenic intron intron intergenic intergenic intergenic intergenic intron intergenic intergenic intron intron intron

0.071 0.055 -0.009 -0.174 -0.098 0.287 0.108 0.027 . . 0.047 . -0.09 0.089 -0.102 -0.117 0.104 -0.03 -0.111 . 0.321 -0.167 0.12 0.503 . 1.19 0.166 0.439 -0.179 0.214 0.277 0.394 0.394 0.832 0.201 -0.133 . 0.11 0.11 1.16 1.16 0.172 0.172 2.521 2.521 0.259 . . 0.192 0.324 0.234 0.296 . . . . . 0.288 0.082 0.206 0.08 0.199 . . 0.332 . 0.356 . -0.054 1.257 0.201 0.183 . . 0.991 1.046 . . . 0.288 . 0.249 1.387 0.168

rs786924206 554949 rs7898 . 652587 rs7892 rs790965648 rs791322105 . rs788199323 . 438241 rs7902 rs706766647 rs787132390 rs792128324 rs788721642 rs790222114 rs789002036 584087 rs7873 . rs791012087 834627 rs7865 . rs791081278 rs791679163 . . rs786329981 027228 rs7868 rs791589891 rs787039018 267042 rs7883 401113 rs7897 rs786962198 rs786962198 rs790707238 rs792940012 rs790370417 . 258526 rs7880 258526 rs7880 rs789947516 rs789947516 . . rs786995489 rs786995489 101904 rs7880 712608 rs7925 rs792679049 rs791822984 253158 rs7867 . rs788994166 rs790340445 . . . . 805106 rs7921 . . 680873 rs7915 rs701838177 rs788941513 rs790797808 rs793212250 461469 rs7875 rs786472882 rs791986828 rs791021559 rs789220647 846040 rs7889 rs792620983 rs792834602 rs792834602 . 592279 rs7924 785058 rs7912 rs786943066 061095 rs7876 rs788382426 rs792526266 rs788134555 rs709800826 rs791633225

2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 3 2 2 2 2 2 2 4 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 3 3 2 2 3 3 3 2 2 2 2 2 2 2 4 4 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2

AAAG.CTTT AC.GT AT.AT AC.GT AAAC.GTTT AG.CT AAAC.GTTT AAAAG.CTTTT AAAC.GTTT AAGG.CCTT AAC.GTT ACAG.CTGT AAAAC.GTTTT AC.GT AAAC.GTTT AC.GT AAAC.GTTT AC.GT AC.GT AT.AT AG.CT AAAAAC.GTTTTT AAC.GTT AAAT.ATTT AAC.GTT AC.GT AAAC.GTTT AC.GT AG.CT AAAACC.GGTTTT AAAT.ATTT AAAC.GTTT AC.GT AC.GT AAAAC.GTTTT AAAT.ATTT AAAC.GTTT AG.CT AG.CT AAAT.ATTT AG.CT AC.GT AAT.ATT AC.GT AT.AT AC.GT AC.GT AAAAT.ATTTT AGAT.ATCT AG.CT AC.GT AC.GT AC.GT AAC.GTT AT.AT AT.AT AC.GT AAAC.GTTT AAAC.GTTT AAG.CTT AAT.ATT AGG.CCT AT.AT AAG.CTT AAAC.GTTT AGG.CCT AC.GT AC.GT AAAAAC.GTTTTT AC.GT AGC.GCT AAAC.GTTT AAAAC.GTTTT AAAC.GTTT AC.GT AAAAC.GTTTT AT.AT AC.GT AT.AT AAAAC.GTTTT AAAT.ATTT AAAT.ATTT AC.GT AAAAC.GTTTT

6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7

154002722 154248484 154338369 154373225 154824657 154918448 155382385 155559175 155891468 156052678 156056255 156110443 156142403 156220284 156369860 157304284 157704796 141486 1333772 1406746 1669546 2584410 2745136 3478394 4031400 4048436 4091287 4137935 4154815 4506722 4844338 5131967 5410383 5432175 5452038 5489363 5808764 5835231 5857323 5980520 6004186 6090436 6150514 6237781 6343089 6497391 6559133 6575635 6681731 6689599 6708791 6847369 6901035 6924080 7051357 7051357 7076877 7101060 7115576 7123813 7143716 7542088 7667644 7703272 7745888 8015620 8336332 8376005 8608864 8622949 8720697 8940167 9043885 9318041 9518712 9533420 9778083 9799685 10295222 10508926 10547710 10553874 10697717 10739020

154002734 154248494 154338387 154373238 154824677 154918462 155382408 155559200 155891490 156052696 156056271 156110461 156142417 156220296 156369878 157304295 157704826 141495 1333787 1406755 1669557 2584439 2745149 3478409 4031421 4048470 4091301 4137956 4154838 4506740 4844354 5131985 5410393 5432185 5452057 5489379 5808782 5835242 5857333 5980540 6004198 6090450 6150525 6237791 6343100 6497403 6559145 6575660 6681748 6689611 6708809 6847403 6901045 6924095 7051366 7051366 7076887 7101072 7115603 7123834 7143739 7542109 7667655 7703285 7745902 8015639 8336343 8376018 8608882 8622961 8720711 8940179 9043915 9318070 9518725 9533442 9778092 9799696 10295232 10508946 10547732 10553900 10697728 10739054

3.25 5.5 9.5 7 5.25 7.5 6 5.2 5.75 4.75 5.66667 4.75 3 6.5 4.75 6 7.75 5 8 5 6 5 4.66667 4 7.33333 17.5 3.75 11 12 3.16667 4.25 4.75 5.5 5.5 4 4.25 4.75 6 5.5 5.25 6.5 7.5 4 5.5 6 6.5 6.5 5.2 4.5 6.5 9.5 17.5 5.5 5.33333 5 5 5.5 3.25 7 7.33333 8 7.33333 6 4.66667 3.75 6.66667 6 7 3.16667 6.5 5 3.25 6.2 7.5 7 4.6 5 6 5.5 4.2 5.75 6.75 6 7

ENSSSCT00000004347 . . . . ENSSSCT00000026482 . . . ENSSSCT00000023375 ENSSSCT00000023375 ENSSSCT00000023375 . . ENSSSCT00000004388 . ENSSSCT00000004405 ENSSSCT00000001075 ENSSSCT00000001084 . . . . ENSSSCT00000001108 ENSSSCT00000035671 ENSSSCT00000035671 ENSSSCT00000035671 . . . . . ENSSSCT00000001123 ENSSSCT00000027153 ENSSSCT00000027153 . ENSSSCT00000001126 . . . . . . . . . . . . . . . . . ENSSSCT00000001128 ENSSSCT00000022619 . . . . . ENSSSCT00000001129 . ENSSSCT00000001133 ENSSSCT00000001134 ENSSSCT00000001139 . . ENSSSCT00000001142 ENSSSCT00000001142 ENSSSCT00000001141 ENSSSCT00000001143 ENSSSCT00000001143 . ENSSSCT00000001146 ENSSSCT00000001146 ENSSSCT00000001146 ENSSSCT00000001146 ENSSSCT00000001150 . . ENSSSCT00000001151 ENSSSCT00000033515 ENSSSCT00000033515

KIF2C . . . . . . . . ERMAP ERMAP ERMAP . . ZMYND12 . SMAP1L EXOC2 GMDS . . . . . F13A1 F13A1 F13A1 . . . . . . . . . SLC35B3 . . . . . . . . . . . . . . . . . OFCC1 OFCC1 . . . . . TFAP2A . GCNT2 C6orf52 ELOVL2 . . . . . HIVEP1 HIVEP1 . . . . . RANBP9 . . MCUR1 CD83 CD83

intron intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intron intron intron intergenic intergenic intron intergenic intron intron intron intergenic intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intron intergenic intron intron promoter intergenic intergenic intron intron intron intron intron intergenic intron intron intron intron intron intergenic intergenic intron intron intron

0.168 0.028 -0.17 . 0.098 0.029 . . -0.082 . . 0.09 0.258 0.198 0.042 . . . 0.55 0.058 0.014 . 0.59 0.043 -0.207 -0.072 -0.032 0.616 . 0.39 . 0.463 0.124 . -0.014 0.127 0.106 -0.113 -0.098 . -0.218 . 0.026 0.022 0.042 0.347 -0.277 -0.003 . -0.24 . 0.341 -0.011 0.257 0.194 0.194 -0.165 -0.033 0.497 2.922 . 0.433 . 0.09 0.056 0.062 -0.022 0.508 0.27 -0.312 . -0.169 0.059 0.004 0.266 0.041 0.056 0.189 0.077 0.016 0.33 -0.17 0.189 0.012

rs791633225 . 256890 rs7910 rs788735344 rs787980239 rs791695123 rs788529566 rs789946111 rs793010068 364712 rs7864 rs791867563 rs786742833 929423 rs7905 rs787485613 940968 rs7920 . 962918 rs7902 rs786439632 rs793576909 rs786481894 rs789839908 rs791686994 rs787563117 rs793115973 rs790658620 rs787446570 . rs790993589 643425 rs7874 rs789392018 . 896336 rs7897 rs790644361 rs793022513 rs787569966 404015 rs7937 rs792951049 rs788258949 rs786931576 . . rs790572046 rs791444549 . rs788401865 rs690642460 . 348879 rs7913 095198 rs7932 . 084847 rs7897 rs792419482 rs789110753 965975 rs7867 rs787311678 rs787311678 rs788230583 rs787209823 444574 rs7912 866051 rs7898 rs790908903 . rs789868933 rs787400968 rs791917522 rs787242743 rs788681979 rs787073395 737443 rs7876 . . . 087916 rs7911 726966 rs7919 481231 rs7925 rs786807563 rs788338746 rs792092349 rs788455633 446755 rs7893 rs787864141 927776 rs7909 . rs788033772

2 2 2 4 2 2 3 3 2 2 2 2 2 4 2 2 2 3 2 2 4 2 2 2 2 4 2 2 4 2 3 4 3 3 2 2 2 2 2 2 2 2 2 4 4 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 4 4 2 3 3 2 2 2 2 2 2 2 3 2 2 2 2 2

AC.GT AAC.GTT AG.CT AAAT.ATTT AAAAAG.CTTTTT AAAC.GTTT AAC.GTT AAT.ATT AAAC.GTTT AAAAC.GTTTT AAAC.GTTT ACC.GGT AAAG.CTTT AAAAT.ATTTT AC.GT AACC.GGTT AG.CT AT.AT AAAT.ATTT AG.CT AAAAG.CTTTT AAT.ATT AT.AT AATC.GATT AC.GT AAAC.GTTT AT.AT AAAC.GTTT AC.GT AAT.ATT AAAG.CTTT AAAC.GTTT AG.CT AT.AT AAAAG.CTTTT ACAG.CTGT AAAT.ATTT AG.CT AC.GT AC.GT AG.CT AAAAAC.GTTTTT AAAT.ATTT ACAG.CTGT AT.AT AG.CT ACAG.CTGT AAAT.ATTT AAAC.GTTT AC.GT AG.CT AAC.GTT AAAC.GTTT ATCC.GGAT AAAAT.ATTTT AAAT.ATTT AAAT.ATTT AC.GT AAAT.ATTT AC.GT AG.CT AAC.GTT AAAAT.ATTTT AG.CT AGG.CCT AAAAAG.CTTTTT AAGG.CCTT AAAC.GTTT AC.GT AC.GT AC.GT AT.AT AAAC.GTTT AAC.GTT AT.AT AC.GT AG.CT AATG.CATT ACAT.ATGT AG.CT AAAC.GTTT AG.CT AAAC.GTTT AC.GT

7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7

10786245 11346345 11490878 11611882 11784381 11829126 12204856 12414854 12416480 12465578 12591077 12637988 12664395 12685053 12766383 12849643 12917192 13008037 13211651 13216669 13413337 13632626 13644961 13713501 13773624 13795499 14016199 14028128 14033920 14060161 14074326 14084643 14312392 14312588 14448421 14567486 14725008 14798617 14799316 14863193 15138452 15293372 15357283 15466234 15524752 15613852 15696501 15727715 15955463 16078644 16172633 16355848 16483057 16509195 16524476 16672568 16680507 16719914 16760412 16830665 17025319 17163453 17191305 17530672 17808718 17837621 18156300 18198629 18215943 18278150 18407511 18548909 18553887 18588213 18623423 18643615 18736467 18814139 18858781 18934479 19119708 19252430 19771893 19963387

10786254 11346364 11490894 11611900 11784402 11829140 12204881 12414875 12416502 12465602 12591092 12638002 12664411 12685081 12766395 12849663 12917201 13008048 13211664 13216679 13413359 13632637 13644973 13713528 13773646 13795519 14016208 14028142 14033931 14060185 14074341 14084661 14312403 14312597 14448450 14567508 14725026 14798659 14799325 14863207 15138462 15293394 15357304 15466245 15524763 15613867 15696523 15727733 15955480 16078661 16172642 16355870 16483076 16509213 16524497 16672583 16680520 16719923 16760448 16830676 17025331 17163469 17191329 17530688 17808736 17837642 18156317 18198651 18215955 18278174 18407525 18548921 18553904 18588231 18623439 18643624 18736492 18814150 18858802 18934507 19119723 19252441 19771905 19963407

5 6.66667 8.5 4.75 3.66667 3.75 8.66667 7.33333 5.75 5 4 5 4.25 5.8 6.5 5.25 5 6 3.5 5.5 4.6 4 6.5 7 11.5 5.25 5 3.75 6 8.33333 4 4.75 6 5 6 5.75 4.75 21.5 5 7.5 5.5 3.83333 5.5 3 6 8 5.75 4.75 4.5 9 5 7.66667 5 4.75 4.4 4 3.5 5 9.25 6 6.5 5.66667 5 8.5 6.33333 3.66667 4.5 5.75 6.5 12.5 7.5 6.5 4.5 6.33333 8.5 5 13 3 5.5 14.5 4 6 3.25 10.5

ENSSSCT00000033515 . . . . . ENSSSCT00000001157 . . . . . . . . ENSSSCT00000001159 ENSSSCT00000001160 . . . . . . . . . ENSSSCT00000001163 ENSSSCT00000001163 ENSSSCT00000001163 . . ENSSSCT00000001165 . . . ENSSSCT00000001168 . ENSSSCT00000001171 ENSSSCT00000001171 . . . . . . . . . . . . . ENSSSCT00000001173 ENSSSCT00000001173 ENSSSCT00000001173 . . . . ENSSSCT00000001175 ENSSSCT00000001175 ENSSSCT00000001175 ENSSSCT00000001175 . . . . . . . . . . . . . . . . . . . . .

CD83 . . . . . DTNBP1 . . . . . . . . GMPR ATXN1 . . . . . . . . . . . . . . FAM8A1 . . . TPMT . RNF144B RNF144B . . . . . . . . . . . . . MBOAT1 MBOAT1 MBOAT1 . . . . CDKAL1 CDKAL1 CDKAL1 CDKAL1 . . . . . . . . . . . . . . . . . . . . .

intron intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic promoter intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intron intergenic intergenic intergenic intron intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

-0.099 0.097 0.058 . . -0.02 -0.531 0.29 0.067 -0.007 -0.101 -0.07 -0.046 -0.138 -0.024 0.089 0.383 -0.292 -0.048 0.222 0.236 0.048 . 0.024 -0.318 0.017 -0.05 -0.168 0.414 -0.19 . . 0.158 0.134 0.141 -0.177 . 0.278 0.514 0.142 -0.043 0.231 -0.004 -0.114 0.12 . . . 0.201 . 0.07 3.405 . . -0.01 0.161 -0.039 -0.181 0.336 0.184 -0.105 0.749 . . 0.037 -0.024 0.095 -0.282 0.242 -0.175 0.054 -0.035 0.415 -0.127 0.076 -0.096 -0.006 0.111 -0.19 -0.106 . -0.125 0.126 0.033

rs789670384 rs790192069 rs789136086 966358 rs7907 rs792869996 rs786542311 rs786478051 . . . rs787683444 . rs793545452 rs789074809 rs788872084 . rs792510451 rs790438140 rs789514160 rs791619677 rs788567552 rs792019751 rs702721440 . rs787259881 rs787137628 . rs790323091 . 222734 rs7921 rs786289802 286458 rs7883 . . rs791901855 759863 rs7901 rs786551428 . rs792671403 rs790388552 rs691623607 rs792378113 . . rs690528146 rs706772144 rs786741496 056415 rs7890 rs791464361 . . 581033 rs7906 . rs793468022 rs789357960 rs793172800 rs790209621 029182 rs7900 rs793344903 rs790353822 rs788267200 640639 rs7876 855331 rs7890 . rs791498373 rs788312506 rs786219103 rs786871935 rs786715761 rs793074234 rs791254620 rs695308618 rs789893385 455692 rs7937 rs787043206 882976 rs7862 441216 rs7921 . rs786524988 rs792514928 rs791086713 rs787706122 rs791020210 rs793491993

2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 4 2 4 3 2 2 2 2 2 3 2 2 2 3 2 2 2 2 4 2 4 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 3 2 4 2 2 2 2 2 3 2 4 2 2 2 4 2 3 2 2 2 2 2 2

AAG.CTT AG.CT AAAAC.GTTTT AC.GT AAAAC.GTTTT AAAAC.GTTTT AAAAC.GTTTT AAAAG.CTTTT AAAAG.CTTTT AC.GT AC.GT AC.GT AC.GT AC.GT AT.AT AAAAC.GTTTT AAAC.GTTT AT.AT AAAAC.GTTTT AAT.ATT AATC.GATT AT.AT AAC.GTT AC.GT AAAC.GTTT AAC.GTT AAAAC.GTTTT AAAC.GTTT AAC.GTT AAAC.GTTT AAAC.GTTT AAAG.CTTT AGG.CCT AG.CT AAT.ATT AAAG.CTTT AAAT.ATTT AAAC.GTTT AT.AT AAAT.ATTT AC.GT AT.AT AC.GT AC.GT AC.GT AT.AT AAACC.GGTTT AC.GT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AAAG.CTTT AC.GT AC.GT AC.GT AC.GT AC.GT AC.GT AC.GT AC.GT AAG.CTT AG.CT AAAC.GTTT ACT.AGT AAAAAG.CTTTTT AG.CT AAAT.ATTT AT.AT ACACAG.CTGTG AAAC.GTTT AC.GT AT.AT AC.GT AAG.CTT AAG.CTT AAAC.GTTT AAAC.GTTT AAG.CTT AT.AT AAAT.ATTT AC.GT

7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7

20028740 20085383 20179329 20195229 20333175 20333175 20333175 20346143 20346143 20353021 20353021 20398625 20398625 20413967 20484802 20632025 20854796 20923331 20928477 20963840 21135552 21297140 21529494 21530008 21958348 22076620 22406727 22496594 22497519 22984362 23201303 23218063 23292184 23328086 24035365 24193472 24206070 24207644 24453527 24824478 25386286 26308177 26767113 26989700 26989700 27324551 27330337 27342765 27612952 27612952 27612952 27612952 27612952 27612952 27731115 28033052 28033052 28033052 28033052 28033052 28033052 29180254 29918137 30021904 30047304 30107579 30496872 30611200 30667308 30687473 30729590 30815255 30930684 31035723 31178650 31217113 31338561 31338561 31345310 31345310 31364950 31475386 31672571 31927718

20028754 20085395 20179348 20195239 20333190 20333190 20333190 20346158 20346158 20353031 20353031 20398647 20398647 20413977 20484814 20632049 20854809 20923341 20928496 20963853 21135579 21297153 21529522 21530019 21958382 22076633 22406750 22496616 22497532 22984383 23201329 23218096 23292202 23328102 24035376 24193509 24206093 24207657 24453537 24824515 25386307 26308189 26767125 26989716 26989716 27324562 27330365 27342784 27612975 27612975 27612975 27612975 27612975 27612975 27731133 28033066 28033066 28033066 28033066 28033066 28033066 29180264 29918148 30021917 30047318 30107605 30496913 30611223 30667322 30687495 30729600 30815276 30930712 31035732 31178661 31217123 31338574 31338574 31345324 31345324 31364978 31475396 31672588 31927729

5 6.5 4 5.5 3.2 3.2 3.2 3.2 3.2 5.5 5.5 11.5 11.5 5.5 6.5 5 3.5 5.5 4 4.66667 7 7 9.66667 6 8.75 4.66667 4.8 5.75 4.66667 5.5 6.75 8.5 6.33333 8.5 4 9.5 6 3.5 5.5 9.5 11 6.5 6.5 8.5 8.5 6 5.8 10 8 8 8 8 8 8 4.75 7.5 7.5 7.5 7.5 7.5 7.5 5.5 6 4.66667 7.5 6.75 14 4 7.5 5.75 5.5 3.66667 7.25 5 6 5.5 4.66667 4.66667 3.75 3.75 9.66667 5.5 4.5 6

. . . . ENSSSCT00000033956 ENSSSCT00000001180 ENSSSCT00000022214 ENSSSCT00000033956 ENSSSCT00000001180 ENSSSCT00000033956 ENSSSCT00000001180 ENSSSCT00000001183 ENSSSCT00000019917 ENSSSCT00000001183 ENSSSCT00000001185 . ENSSSCT00000001193 . . . . . ENSSSCT00000001196 ENSSSCT00000001196 . . . . . . . . . . ENSSSCT00000001302 . . . ENSSSCT00000001317 . ENSSSCT00000030258 . . ENSSSCT00000034652 ENSSSCT00000031071 . . . ENSSSCT00000034604 ENSSSCT00000034735 ENSSSCT00000035823 ENSSSCT00000001524 ENSSSCT00000001336 ENSSSCT00000035331 ENSSSCT00000001570 ENSSSCT00000001583 ENSSSCT00000035347 ENSSSCT00000036330 ENSSSCT00000033826 ENSSSCT00000035535 ENSSSCT00000033020 ENSSSCT00000034363 ENSSSCT00000001649 . . . . ENSSSCT00000001655 . . . . . . . . ENSSSCT00000001658 ENSSSCT00000035077 ENSSSCT00000001658 ENSSSCT00000035077 ENSSSCT00000001658 . . .

. intergenic . intergenic . intergenic . intergenic DCDC2 intron DCDC2 intron 5S_rRNA promoter DCDC2 intron DCDC2 intron DCDC2 intron DCDC2 intron MRS2 intron SNORA11 promoter MRS2 intron GPLD1 intron . intergenic FAM65B intron . intergenic . intergenic . intergenic . intergenic . intergenic LRRC16A intron LRRC16A intron . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . promoter . intergenic . intergenic . intergenic TRIM27 promoter . intergenic U6 promoter . intergenic . intergenic IER3 promoter IER3 promoter . intergenic . intergenic . intergenic SLA-7 promoter SLA-7 promoter SLA-7 promoter SLA-7 promoter SLA-7 promoter SLA-7 promoter C4A intron AGPAT1 intron AGPAT1 intron AGPAT1 intron AGPAT1 intron AGPAT1 intron AGPAT1 intron SLA-DQB2 promoter BMP5 intron . intergenic . intergenic . intergenic . intergenic FAM83B promoter . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic LRRC1 intron LRRC1 intron LRRC1 intron LRRC1 intron LRRC1 intron . intergenic . intergenic . intergenic

. -0.027 . 0.072 -0.278 -0.278 -0.278 0.106 0.106 0.104 0.104 0.034 0.034 . -0.087 0.089 0.401 -0.025 0.243 . . 0.068 0.131 0.888 -0.169 -0.024 . . . 0.019 . . . . 0.338 . -0.194 -0.129 . . . . . 0.017 0.017 . . . -0.874 -0.874 -0.874 -0.874 -0.874 -0.874 -0.296 -0.001 -0.001 -0.001 -0.001 -0.001 -0.001 -0.079 0.202 0.577 . 0.024 -0.041 0.01 0.083 0.025 . 0.036 0.063 . . -0.086 -0.018 -0.018 1.204 1.204 0.133 . 0.197 -0.035

rs787559250 . rs788934363 rs788112684 . . . rs792205789 rs792205789 rs702350524 rs702350524 941571 rs7906 941571 rs7906 rs793666164 rs793387443 806321 rs7880 234407 rs7900 rs790602223 rs793858319 . rs787593181 rs790417878 rs712248884 754523 rs7901 468779 rs7920 534780 rs7896 206016 rs7911 rs792390872 rs786760082 026477 rs7914 rs786313812 rs786816087 592268 rs7879 . . 398431 rs7878 895276 rs7935 rs787823562 . rs704523262 rs791148392 609324 rs7915 rs791851405 rs790175622 rs790175622 rs793204991 295739 rs7930 144196 rs7864 640367 rs7865 640367 rs7865 640367 rs7865 640367 rs7865 640367 rs7865 640367 rs7865 378311 rs7896 rs789711840 rs789711840 rs789711840 rs789711840 rs789711840 rs789711840 097584 rs7936 681700 rs7877 768426 rs7871 rs693921366 774541 rs7893 436151 rs7887 rs790534615 . . rs788006516 rs793290575 rs788175492 rs691303695 rs693563455 rs786307573 rs791129679 rs791129679 691858 rs7863 691858 rs7863 rs787503452 rs791843000 . 124323 rs7908

2 4 2 2 3 3 3 2 2 2 2 2 2 2 2 2 2 3 3 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 3 3 3 3 3 2 2 2 4 2 2 2 3 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2

AG.CT AAAAT.ATTTT AAAG.CTTT AAC.GTT AAAAC.GTTTT AAAC.GTTT AC.GT AAAC.GTTT AT.AT AAAC.GTTT AC.GT AAAAT.ATTTT AAAT.ATTT AAAAGC.GCTTTT ATC.GAT AC.GT AC.GT AT.AT AATG.CATT AT.AT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AT.AT AC.GT AC.GT AG.CT AC.GT AC.GT AG.CT AT.AT AAC.GTT AAAC.GTTT AAC.GTT ACAT.ATGT AC.GT AC.GT AAAAC.GTTTT AT.AT AAAC.GTTT AAAAC.GTTTT AT.AT AAAT.ATTT AAAC.GTTT AAAAC.GTTTT AAT.ATT AAAC.GTTT AC.GT AC.GT AATT.AATT AAAC.GTTT AGG.CCT AAAC.GTTT AC.GT AG.CT AAAT.ATTT AAAG.CTTT AAAG.CTTT AAAG.CTTT AC.GT AC.GT AC.GT AAAGC.GCTTT AAAC.GTTT AAAC.GTTT AT.AT AC.GT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AAT.ATT AAT.ATT AATG.CATT AAC.GTT AAAC.GTTT AATG.CATT AATG.CATT AC.GT AG.CT AAAG.CTTT AAAC.GTTT AAC.GTT

7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7

32003793 32251260 32282712 32283886 32287437 32606104 32956636 33085156 33152415 33296481 33300385 33363364 33931712 33992799 34019373 34162365 34196564 34525207 34875026 35514892 36150545 36307815 36309169 36332078 36501047 37241843 37392954 37450177 37450177 37462933 37957294 38019424 38064266 38212286 38850068 38934485 38982481 39374338 39448720 39466142 39489154 39603051 39645056 39661167 39662418 39766859 40069540 40213384 40428794 40529395 40532592 40533291 40552978 40909564 40967916 41524081 41708556 41708556 41708556 41717657 41717657 41717657 41760464 41827962 42130525 42852026 42912451 42916402 43150396 43549482 43629247 43742558 43768435 43768435 43797160 44687221 45072433 45128625 45128625 45740913 45823338 46086137 46186415 46365927

32003804 32251278 32282740 32283897 32287470 32606129 32956647 33085170 33152427 33296493 33300397 33363396 33931732 33992820 34019388 34162380 34196580 34525219 34875053 35514913 36150568 36307827 36309185 36332087 36501063 37241858 37392963 37450190 37450190 37462942 37957303 38019451 38064280 38212302 38850090 38934498 38982493 39374362 39448736 39466172 39489173 39603062 39645074 39661181 39662432 39766873 40069558 40213396 40428812 40529412 40532611 40533305 40552993 40909575 40967929 41524099 41708568 41708568 41708568 41717668 41717668 41717668 41760492 41827979 42130544 42852035 42912463 42916426 43150414 43549500 43629264 43742572 43768451 43768451 43797186 44687242 45072456 45128644 45128644 45740923 45823354 46086151 46186434 46365939

6 3.8 7.25 4 6.8 6.5 6 3.75 6.5 3.25 6.5 6.6 5.25 3.66667 5.33333 8 8.5 6.5 7 11 4.8 3.25 4.25 5 8.5 8 5 7 7 5 5 9.33333 3.75 5.66667 5.75 7 6.5 5 8.5 7.75 4 6 4.75 3.75 3 5 4.75 6.5 9.5 4.5 5 5 4 6 7 4.75 3.25 3.25 3.25 6 6 6 5.8 4.5 5 5 6.5 6.25 4.75 3.8 4.5 3.75 5.66667 5.66667 6.75 7.33333 6 5 5 5.5 8.5 3.75 5 4.33333

ENSSSCT00000001662 KHDRBS2 intron ENSSSCT00000001662 KHDRBS2 intron ENSSSCT00000001662 KHDRBS2 intron ENSSSCT00000001662 KHDRBS2 intron ENSSSCT00000001662 KHDRBS2 intron . . intergenic ENSSSCT00000001665 . intron . . intergenic ENSSSCT00000001669 ZNF451 intron ENSSSCT00000027614 . intron ENSSSCT00000027614 . intron ENSSSCT00000027614 . intron ENSSSCT00000001673 COL21A1 intron ENSSSCT00000001673 COL21A1 intron . . intergenic ENSSSCT00000001679 RGL2 intron ENSSSCT00000001683 . promoter ENSSSCT00000030529 UQCC2 intron ENSSSCT00000001696 GRM4 intron ENSSSCT00000001707 UHRF1BP1 intron ENSSSCT00000001714 PPARD intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000001746 CPNE5 intron ENSSSCT00000028714 PPIL1 promoter ENSSSCT00000001748 C6orf89 promoter ENSSSCT00000001748 C6orf89 intron ENSSSCT00000001758 . intron . . intergenic . . intergenic . . intergenic ENSSSCT00000001764 . intron . . intergenic ENSSSCT00000026749 BTBD9 intron ENSSSCT00000001768 DNAH8 intron ENSSSCT00000001768 DNAH8 intron ENSSSCT00000001768 DNAH8 intron ENSSSCT00000001768 DNAH8 intron ENSSSCT00000001769 GLP1R intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000001774 KIF6 intron . . intergenic ENSSSCT00000001776 MOCS1 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000001777 LRFN2 intron . . intergenic . . intergenic ENSSSCT00000001792 . intron ENSSSCT00000030920 . intron ENSSSCT00000027428 . intron ENSSSCT00000001792 . intron ENSSSCT00000030920 . intron ENSSSCT00000027428 . intron . . intergenic . . intergenic ENSSSCT00000001801 MDFI intron . . intergenic . . intergenic . . intergenic ENSSSCT00000001825 . intron ENSSSCT00000001847 CUL7 intron ENSSSCT00000001850 KLC4 intron ENSSSCT00000030706 CUL9 intron ENSSSCT00000001861 C6ORF108 promoter ENSSSCT00000001854 C6ORF108 promoter ENSSSCT00000001855 TTBK1 intron . . intergenic . . intergenic ENSSSCT00000001903 NFKBIE intron ENSSSCT00000032591 NFKBIE intron ENSSSCT00000001909 . intron ENSSSCT00000001909 . intron . . intergenic . . intergenic ENSSSCT00000023043 . intron

0.032 0.307 0.006 0.074 0.024 0.036 . 0.159 . 0.042 0.272 -0.218 0.508 2.507 . 0.698 . . -0.067 0.152 . . 0.042 0.289 0.073 -0.314 -0.242 . . 2.163 . -0.073 . 0.24 0.046 0.075 0.131 0.056 -0.096 2.025 -0.271 -0.157 0.129 . 0.148 . 2.713 0.042 0.301 . . . . -0.334 . -0.055 -0.015 -0.015 -0.015 0.5 0.5 0.5 -0.477 0.169 -0.304 -0.256 . -0.096 0.151 1.009 0.122 0.293 . . -0.046 1.167 0.032 0.932 0.932 0.814 . 0.283 . -0.02

rs708215496 rs792943635 rs793623095 . rs790538024 438071 rs7902 rs790137445 rs789452636 . rs787568404 rs789053295 rs793153182 rs789082287 . rs788263076 rs789752821 411726 rs7921 rs789596352 880977 rs7905 663152 rs7903 rs792933705 rs793712938 917874 rs7887 rs789234251 rs787270603 608771 rs7878 rs791538642 rs791513936 rs791513936 rs787595822 rs791495289 . rs694927431 932366 rs7903 rs792516526 . 349742 rs7882 217261 rs7865 rs792135154 991472 rs7930 rs788186435 rs698989796 973396 rs7889 rs786623952 rs786394230 rs792851490 460206 rs7905 . 441187 rs7936 393969 rs7916 024363 rs7916 672345 rs7917 . rs789335130 rs793741467 rs788744413 rs793812660 rs793812660 rs793812660 851155 rs7914 851155 rs7914 851155 rs7914 280355 rs7882 . . rs786454887 rs788967366 540068 rs7883 rs793128882 rs792043476 rs787418887 . 349946 rs7930 349946 rs7930 rs790322811 rs788002630 rs791006420 rs792993713 rs792993713 rs709857311 . rs793115164 . 818136 rs7934

3 2 2 2 3 2 3 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 3 3 3 3 2 2 3 2 2 3 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2

AG.CT AAC.GTT AC.GT AAC.GTT AAAAC.GTTTT AG.CT AATG.CATT AAAT.ATTT AAAAT.ATTTT AC.GT AAAAC.GTTTT AAC.GTT AAC.GTT AAAC.GTTT AT.AT AAAAT.ATTTT AG.CT AT.AT AAAC.GTTT AAAC.GTTT AAAAT.ATTTT AAAAT.ATTTT AATT.AATT AAAT.ATTT AAAAC.GTTTT AC.GT AG.CT AG.CT AT.AT AC.GT AAAAG.CTTTT AAAAC.GTTTT AT.AT AAAAT.ATTTT AG.CT AAAAC.GTTTT AACC.GGTT AAAC.GTTT AG.CT AAAT.ATTT AG.CT AAAAG.CTTTT AAAC.GTTT AC.GT AT.AT ACACAT.ATGTGT AT.AT AG.CT AAAC.GTTT AAT.ATT AC.GT AT.AT AAAC.GTTT AC.GT AG.CT AC.GT AAAAT.ATTTT AT.AT AT.AT AG.CT AT.AT AC.GT AAAAAC.GTTTTT AAT.ATT AAAAC.GTTTT AGGG.CCCT AT.AT AATG.CATT AT.AT AC.GT AC.GT AC.GT AAAC.GTTT AAAC.GTTT AAAC.GTTT AC.GT AG.CT AAAC.GTTT AAAG.CTTT AAG.CTT AT.AT AAAC.GTTT AAAC.GTTT AAAT.ATTT

7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7

46398814 46892875 47053353 47184859 47205432 47408734 47440400 48187218 48194418 48383964 48397104 48470831 48521588 48619486 48665518 48786826 48828044 48852344 48873416 48945324 49091755 49100709 49170585 49195248 49220297 49574606 49625954 49676584 49687496 49785098 49988076 50014501 50289991 50399073 50575022 50580836 50854266 51011333 51013146 51047596 51078190 51788391 51795401 52139025 52192035 52226615 52285592 52302478 52471799 52927139 52950046 53382728 53434484 53777933 53826747 53836002 53859608 53946103 53994318 54061586 54076578 54429804 54505760 54510556 54599104 54695801 55323126 55361376 55446112 55593319 55593319 55593319 55683261 55683261 55683261 55712852 55897730 56037274 56041567 56260856 56282282 56400532 56400532 56496772

46398830 46892888 47053369 47184878 47205447 47408748 47440433 48187234 48194444 48383982 48397134 48470851 48521613 48619504 48665532 48786848 48828056 48852354 48873437 48945338 49091779 49100727 49170602 49195270 49220314 49574620 49625965 49676620 49687506 49785118 49988093 50014515 50290000 50399096 50575034 50580857 50854297 51011353 51013159 51047614 51078209 51788406 51795420 52139049 52192045 52226642 52285623 52302490 52471814 52927163 52950056 53382737 53434505 53777944 53826757 53836012 53859632 53946115 53994328 54061602 54076590 54429818 54505781 54510572 54599124 54695818 55323137 55361393 55446127 55593329 55593329 55593329 55683284 55683284 55683284 55712862 55897748 56037294 56041578 56260881 56282291 56400548 56400548 56496801

8.5 4.66667 8.5 6.66667 3.2 7.5 8.5 4.25 5.4 9.5 6.2 7 8.66667 4.75 7.5 4.6 6.5 5.5 5.5 3.75 5 3.8 4.5 5.75 3.6 7.5 6 18.5 5.5 10.5 3.6 3 5 4.8 6.5 4.4 8 5.25 7 4.75 10 3.2 5 12.5 5.5 4.66667 16 6.5 4 8.33333 5.5 5 5.5 6 5.5 5.5 5 6.5 5.5 8.5 6.5 7.5 3.66667 5.66667 4.2 4.5 6 4.5 8 5.5 5.5 5.5 6 6 6 5.5 9.5 5.25 3 8.66667 5 4.25 4.25 7.5

ENSSSCT00000023043 . ENSSSCT00000001911 . . ENSSSCT00000001918 ENSSSCT00000001918 . . ENSSSCT00000001929 ENSSSCT00000001929 ENSSSCT00000001930 . . . . . . . ENSSSCT00000001932 ENSSSCT00000001933 ENSSSCT00000001933 . . . . . . . . . . ENSSSCT00000001944 . . . . ENSSSCT00000001950 ENSSSCT00000001950 ENSSSCT00000001950 . . . ENSSSCT00000001952 ENSSSCT00000001952 ENSSSCT00000001952 ENSSSCT00000001952 ENSSSCT00000001952 . . ENSSSCT00000001961 . ENSSSCT00000032525 ENSSSCT00000001986 . . . . . ENSSSCT00000001990 . . ENSSSCT00000001994 ENSSSCT00000001994 . . . . . ENSSSCT00000035382 ENSSSCT00000025614 ENSSSCT00000034701 ENSSSCT00000035382 ENSSSCT00000034701 ENSSSCT00000002002 ENSSSCT00000002003 . . . . . ENSSSCT00000002007 ENSSSCT00000002008 .

. . CLIC5 . . RCAN2 RCAN2 . . GPR116 GPR116 GPR110 . . . . . . . . . . . . . . . . . . . . CRISP1 . . . . TFAP2D TFAP2D TFAP2D . . . . . . . . . . HYKK . . RASGRF1 . . . . . KIAA1024 . . ZFAND6 ZFAND6 . . . . . IL-16 IL-16 IL-16 IL-16 IL-16 IL-16 STARD5 . . . . . . . .

intron intergenic intron intergenic intergenic intron intron intergenic intergenic intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intron intron intron intron intron intergenic intergenic intron intergenic intron intron intergenic intergenic intergenic intergenic intergenic promoter intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron promoter intron intergenic intergenic intergenic intergenic intergenic intron promoter intergenic

1.497 . -0.037 . . 0.027 0.397 . -0.051 -0.691 . . 0.279 0.143 0.077 0.006 0.109 0.07 0.123 0.16 -0.028 -0.035 0.044 . -0.043 0.033 . 0.127 . . 0.043 0.032 -0.122 -0.077 . -0.134 -0.096 0.113 -0.037 0.077 0.037 0.039 . 0.033 . 0.109 -0.186 0.549 0.318 0.287 0.075 0.204 -0.048 -0.087 -0.072 -0.025 . 0.06 0.058 1.246 0.294 . . 0.079 -0.019 -0.16 0.091 1.072 -0.04 -0.15 -0.15 -0.15 -0.139 -0.139 -0.139 0.018 -0.221 . . -0.29 -0.011 . . .

rs792944058 134247 rs7925 239149 rs7931 rs790867464 rs792358850 rs787496928 056613 rs7890 rs792115996 rs787947387 74880 rs79343 860378 rs6989 rs791196014 rs790776240 rs788091187 . rs791275475 866751 rs7907 382651 rs7862 560121 rs7926 rs786230801 . . 120140 rs7914 535268 rs7915 090574 rs7870 715745 rs7932 . 352180 rs7895 365293 rs7920 . . 752842 rs7881 . . rs791311865 rs789993159 rs788052512 482265 rs7898 . . rs711869631 rs786562515 rs705433247 rs791005458 . rs788239110 rs791216632 . 423835 rs7930 025269 rs7894 rs791539519 rs792515055 643859 rs7931 954953 rs7079 rs790142400 rs789314176 rs791153045 040957 rs7937 rs791321750 rs788603802 rs789626198 rs793787994 437464 rs7929 573213 rs7864 rs792123937 008225 rs7921 rs788576756 . rs787131537 rs708607449 rs708607449 rs708607449 709487 rs7900 709487 rs7900 709487 rs7900 rs793270793 412877 rs7880 556325 rs7893 . . rs793448581 rs786915599 rs786915599 588127 rs7907

3 2 2 2 2 2 2 2 4 6 3 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 4 2 2 2 2 2 2 2 3 2 2 2 2 4 2 2 2 2 4 2 3 2 2 2 2 2 2 3 2 2 3 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2

AAAC.GTTT AT.AT AT.AT AAAC.GTTT AC.GT AC.GT AAAT.ATTT AG.CT AAAC.GTTT AAAC.GTTT AAC.GTT AAAT.ATTT AAAC.GTTT AG.CT AAAAAC.GTTTTT AC.GT AAAAG.CTTTT AAAC.GTTT AT.AT AC.GT AAAC.GTTT AAAC.GTTT ATC.GAT AAC.GTT AC.GT AAC.GTT ACAT.ATGT AAAT.ATTT AAGG.CCTT AG.CT ATC.GAT AAGT.ACTT AAAT.ATTT AAAC.GTTT AC.GT AAAAG.CTTTT AAAT.ATTT AAAAAC.GTTTTT AAAC.GTTT AAG.CTT AC.GT AAAC.GTTT AAAAC.GTTTT AAAC.GTTT AG.CT AGAT.ATCT AAAAG.CTTTT AAAT.ATTT AAAT.ATTT AAAC.GTTT ACCT.AGGT AT.AT AT.AT AATG.CATT AAAAC.GTTTT AAC.GTT ATCC.GGAT AAAT.ATTT AC.GT AC.GT AAAAT.ATTTT AATATC.GATATT AAAT.ATTT AAAT.ATTT AAT.ATT ACTAT.ATAGT AAAC.GTTT AT.AT AT.AT AC.GT AATT.AATT AAG.CTT AAAC.GTTT AAAT.ATTT AAAG.CTTT AT.AT AC.GT AATG.CATT AAAC.GTTT AT.AT AT.AT AAG.CTT AC.GT AG.CT

7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7

56510790 56661087 56816073 56833841 56907248 56907248 57209890 57518253 57537546 57556317 57562119 57619571 57624999 57639588 57650324 57762507 57884571 57971678 58211090 58816274 58900476 59510939 59835081 60154250 60170573 60313453 60374230 60654649 60773497 61802267 61829299 61831977 61950143 62474168 62680977 62788599 62985914 63005980 63210351 63752936 63934701 64054489 64134096 64135423 64159135 64202830 64470478 65191109 65191109 65321659 65330258 65708025 66323236 66375733 66614785 67621606 67724684 67759605 67977578 68082885 68187046 68431907 68496545 68508092 68541439 68980793 69130279 69157085 69347307 69459253 69664806 70019404 70024300 70049058 70078406 70189860 70200785 70469199 70559440 70695653 70787601 71048902 71390323 71472848

56510802 56661097 56816088 56833859 56907259 56907259 57209908 57518263 57537568 57556339 57562146 57619599 57625017 57639611 57650354 57762520 57884592 57971692 58211104 58816286 58900494 59510953 59835109 60154275 60170583 60313475 60374248 60654676 60773515 61802281 61829322 61831993 61950161 62474200 62680997 62788618 62985939 63006002 63210374 63752969 63934723 64054510 64134123 64135441 64159152 64202852 64470496 65191122 65191122 65321674 65330283 65708035 66323252 66375753 66614808 67621619 67724705 67759622 67977593 68082897 68187068 68431937 68496567 68508112 68541452 68980807 69130302 69157097 69347316 69459268 69664828 70019426 70024320 70049076 70078423 70189873 70200795 70469225 70559462 70695663 70787613 71048913 71390333 71472857

3.25 5.5 8 4.75 6 6 4.75 5.5 5.75 5.75 9.33333 7.25 4.75 12 5.16667 7 4.4 3.75 7.5 6.5 4.75 3.75 9.66667 8.66667 5.5 7.66667 4.75 7 4.75 7.5 8 4.25 4.75 8.25 10.5 4 6.5 3.83333 6 11.3333 11.5 5.5 5.6 4.75 9 5.75 3.8 3.5 3.5 4 6.5 5.5 8.5 5.25 4.8 4.66667 5.5 4.5 8 6.5 4.6 5.16667 5.75 5.25 4.66667 3 6 6.5 5 8 5.75 7.66667 5.25 4.75 4.5 7 5.5 6.75 5.75 5.5 6.5 4 5.5 5

ENSSSCT00000002009 ENSSSCT00000002009 . . ENSSSCT00000002011 ENSSSCT00000029711 . ENSSSCT00000002020 ENSSSCT00000002020 ENSSSCT00000002020 ENSSSCT00000002020 ENSSSCT00000002021 ENSSSCT00000002021 . . ENSSSCT00000002023 . ENSSSCT00000002032 . ENSSSCT00000002046 . ENSSSCT00000002056 ENSSSCT00000002059 ENSSSCT00000022362 ENSSSCT00000002069 ENSSSCT00000025884 . . . . . . . . . ENSSSCT00000002103 . . . . . ENSSSCT00000002141 . . ENSSSCT00000002144 . . ENSSSCT00000002153 ENSSSCT00000002151 ENSSSCT00000030450 ENSSSCT00000030450 ENSSSCT00000002166 . . . . . . . . ENSSSCT00000002174 . . . . . ENSSSCT00000029555 ENSSSCT00000029555 . . ENSSSCT00000002187 ENSSSCT00000020434 . ENSSSCT00000002193 . . . . . ENSSSCT00000002196 . . ENSSSCT00000022418 ENSSSCT00000022418

. . . . SH3GL3 SH3GL3 . HOMER2 HOMER2 HOMER2 HOMER2 WHAMM WHAMM . . . . PDE8A . CCDC37 . MFGE8 FANCI PEX11A WDR93 AP3S2 . . . . . . . . . PTPN9 . . . . . PML . . . . . BBS4 ARIH1 . . . . . . . . . . . SLC25A21 . . . . . . . . . SRP54 U1 . EAPP . . . . . EGLN3 . . . .

intron intron intergenic intergenic intron intron intergenic intron intron intron intron intron intron intergenic intergenic intron intergenic intron intergenic intron intergenic intron intron promoter intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intron intergenic intergenic intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intron promoter intergenic intron intergenic intergenic intergenic intergenic intergenic 3'utr intergenic intergenic intron intron

0.198 . 0.242 0.182 -0.001 -0.001 . -0.374 -0.09 . 0.099 . . 0.025 . 1.402 . 0.053 . . -0.529 . 0.976 . . 0.049 -0.035 . . 0.256 0.105 . 0.187 -0.112 -0.06 0.549 . -0.089 0.333 0.335 -0.129 0.093 . . -0.086 0.169 . 0.131 0.131 0.033 . 0.12 0.446 0.165 0.097 0.048 0.191 0.024 . 0.205 0.157 . 0.169 0.239 . . . . 0.289 -0.011 0.228 0.189 . . . -0.066 . 0.01 0.222 0.801 5.822 0.365 . 0.085

rs793207873 rs790264097 rs706836422 . 633064 rs7874 633064 rs7874 rs791877637 645227 rs7896 196442 rs7869 rs792240050 rs786803206 rs790409472 rs789571532 647094 rs7927 704780 rs7935 rs788368968 293590 rs7870 rs787387482 rs791849710 rs786387265 845034 rs7924 rs789847352 rs791627407 rs786957468 rs786294466 805364 rs7869 rs790159479 471091 rs7874 . rs791465817 . 460962 rs7890 . 406511 rs7914 . rs788332334 rs791440260 rs791749478 rs786568239 rs791575691 . rs791847653 rs790274512 rs790773473 . rs793063296 rs788425896 rs787521357 rs787521357 rs789674067 rs787655448 rs790436710 874460 rs7862 rs792341705 rs791054250 rs788636466 . rs792389911 rs793253034 228187 rs6970 rs792460610 524816 rs7909 840708 rs7911 rs787034732 576656 rs7882 rs789953143 rs788725404 900247 rs7902 . rs790538305 rs791380281 rs791439142 028976 rs7933 rs792805545 rs789542241 . rs791692940 072634 rs7903 rs786803497 rs793084999 rs788033164 074527 rs7905 . rs793603118

2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 3 2 2 2 2 6 2 2 2 3 2 2 2 2 6 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 3 2

AC.GT AC.GT AT.AT AC.GT AAAC.GTTT AAAG.CTTT AAC.GTT AG.CT AG.CT AAAG.CTTT AAAC.GTTT AAAC.GTTT AATC.GATT AAAAC.GTTTT AG.CT AC.GT AC.GT AAAC.GTTT AT.AT AAC.GTT AAAC.GTTT AAAG.CTTT AAC.GTT AT.AT AG.CT AT.AT AAAC.GTTT AGATAT.ATATCT AAAAAT.ATTTTT AT.AT AG.CT AAAT.ATTT AAAAC.GTTTT AC.GT AATC.GATT AG.CT AAAT.ATTT AT.AT AAC.GTT AAAC.GTTT CCCCC.GGGGG AG.CT AG.CT AT.AT AG.CT AG.CT AAT.ATT AAAAC.GTTTT AGAT.ATCT AG.CT AAT.ATT AC.GT AAAAT.ATTTT AT.AT AG.CT AC.GT AAC.GTT AC.GT AAC.GTT AT.AT AAAC.GTTT AAT.ATT ACAT.ATGT AAAAAT.ATTTTT AAAAC.GTTTT AAAAC.GTTTT AT.AT AAAC.GTTT AT.AT AG.CT AT.AT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAGG.CCTT AAAC.GTTT AAAC.GTTT AC.GT AAAAC.GTTTT AATG.CATT AAAT.ATTT AAAC.GTTT AC.GT

7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7

71507826 72213885 72355835 72369037 72487426 72704207 72947280 72963159 72967826 73030946 73906868 74269938 75685810 75879025 75960453 76222333 76384937 76640506 76919177 77112499 77248787 77427615 77589115 77734934 77998659 78096575 78362079 78409092 78455194 78472613 78817411 78976899 79429993 79660047 79844905 79874949 79893646 79896843 80673143 80705247 80706963 81285343 81285343 81662967 81698050 82023644 82030117 82045361 82132773 82172625 83262971 83423601 83431198 83672388 83890276 83913149 84272118 84733600 85918256 86199707 86342388 86365208 86494759 86542973 86591289 86671304 86807141 86810536 86881672 86931053 87505431 87599969 87599969 87600246 87600246 87605900 87699621 87959821 87970152 87995460 88022545 88120190 88326194 88694305

71507837 72213897 72355851 72369048 72487452 72704229 72947296 72963173 72967836 73030963 73906903 74269960 75685833 75879050 75960462 76222348 76384947 76640519 76919202 77112511 77248822 77427636 77589139 77734943 77998682 78096591 78362093 78409120 78455214 78472627 78817425 78976918 79430013 79660057 79844924 79874959 79893670 79896857 80673161 80705261 80706981 81285352 81285352 81662976 81698062 82023659 82030132 82045385 82132787 82172634 83262982 83423619 83431215 83672403 83890286 83913159 84272142 84733623 85918270 86199716 86342406 86365224 86494770 86542999 86591309 86671323 86807152 86810568 86881704 86931063 87505440 87599992 87599992 87600257 87600257 87605923 87699643 87959835 87970165 87995479 88022563 88120204 88326208 88694318

6 6.5 8.5 6 6.75 5.75 5.66667 7.5 5.5 4.5 9 5.75 6 5.2 5 8 5.5 3.5 13 4.33333 9 5.5 8.33333 5 12 8.5 3.75 4.83333 3.5 7.5 7.5 5 4.2 5.5 5 5.5 6.25 7.5 6.33333 3.75 3.16667 5 5 5 6.5 8 5.33333 5 3.75 5 4 9.5 3.6 8 5.5 5.5 8.33333 12 5 5 4.75 5.66667 3 4.5 4.2 4 6 8.25 16.5 5.5 5 6 6 3 3 6 5.75 3.75 7 4 4.75 3.75 3.75 7

ENSSSCT00000022418 ENSSSCT00000002199 ENSSSCT00000028957 ENSSSCT00000028957 . ENSSSCT00000029319 . ENSSSCT00000023087 ENSSSCT00000023087 . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000002211 . . . . . . . ENSSSCT00000002277 ENSSSCT00000002276 . . . . ENSSSCT00000002299 . . . . . . . . . . . ENSSSCT00000002498 . . . . . . . . . . . ENSSSCT00000034830 ENSSSCT00000002508 ENSSSCT00000034830 ENSSSCT00000002508 . . . . . . . . .

. . . . . NUBPL . GPR33 GPR33 . . . . . . . . . . . . . . . . . . . . . . . . STXBP6 . . . . . . . C14orf119 ACIN1 . . . . TRAV41 . . . . . . . . . . . . . . . . . . . . . . . ARRDC4 ARRDC4 ARRDC4 ARRDC4 . . . . . . . . .

intron intron 3'utr intron intergenic intron intergenic promoter intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic promoter promoter intergenic intergenic intergenic intergenic promoter intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic promoter promoter promoter promoter intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

-0.077 . . 0.218 -0.069 0.08 . 0.306 0.166 0.352 . 0.36 0.39 0.227 0.101 . . . 0.111 -0.034 0.031 0.066 -0.163 . 0.145 -0.026 0.003 -0.108 . 0.008 0.2 0.195 0.044 0.292 0.045 0.098 -0.107 -0.22 . 0.19 -0.011 0.301 0.301 0.211 -0.017 . 0.222 0.081 -0.003 -0.03 . 0.133 . . . 0.483 . . . 0.249 0.473 . 0.163 . -0.192 0.162 0.201 0.178 0.109 0.248 0.081 -0.036 -0.036 -0.209 -0.209 -0.229 0.073 . 0.023 -0.113 0.161 -0.033 -0.045 -0.107

. rs790782265 rs793607184 . rs788033881 rs788407071 402806 rs7881 266542 rs7915 . rs789752145 084575 rs7918 rs792980586 rs791010477 rs790286712 . rs793412251 rs788091845 rs791067850 rs789175644 rs793540514 rs790415695 rs786903447 rs793258576 rs789128625 . rs788028593 . rs788154095 rs792566919 rs790271215 rs791770435 . 488751 rs7905 rs788733229 rs793167922 rs707845398 rs787475155 . 106126 rs7931 rs787298150 rs693200018 rs789237906 rs789237906 rs787963477 211181 rs7884 . 653426 rs7925 774133 rs7899 872094 rs7899 . 687422 rs7890 . rs788112670 rs789241421 rs793236199 rs789418865 . . . rs793780149 rs789124154 rs792452402 rs787244082 rs789685734 rs788287887 528616 rs7928 rs792380757 459672 rs7881 rs789125576 . rs790279182 847131 rs7897 847131 rs7897 rs787525351 rs787525351 . rs791665525 rs791411544 rs790905034 rs786330166 rs786325158 863195 rs7884 rs789349595 279323 rs7885

4 2 2 2 3 2 2 3 2 3 4 2 2 2 3 3 3 2 2 2 2 2 3 2 4 2 2 2 2 2 2 2 2 2 2 4 2 4 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 3 3 2 2 2 2 3 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 7 2 2 2 2 2

AAC.GTT AGAT.ATCT AC.GT AGG.CCT AT.AT AC.GT AT.AT AT.AT AG.CT AAAT.ATTT AAAAT.ATTTT AAAC.GTTT AAAT.ATTT AC.GT AC.GT AAAC.GTTT AG.CT AC.GT AAAC.GTTT AAAG.CTTT AAAG.CTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAGC.GCTTT AT.AT AC.GT AC.GT AAAT.ATTT AAAC.GTTT AAAG.CTTT AT.AT AT.AT AATT.AATT AG.CT AG.CT AAAAAC.GTTTTT AGC.GCT AAAG.CTTT AAGG.CCTT AAAAT.ATTTT AAAAC.GTTTT ACAT.ATGT AC.GT AAC.GTT AAAC.GTTT AG.CT AG.CT AAAAC.GTTTT ACC.GGT AC.GT AG.CT AAAAT.ATTTT AG.CT AAAT.ATTT AC.GT AAAAAC.GTTTTT AAAT.ATTT AAAC.GTTT AC.GT AAAC.GTTT AAAC.GTTT AAAAT.ATTTT AAAAT.ATTTT AAAAT.ATTTT AAAAT.ATTTT AAAT.ATTT AC.GT AAAG.CTTT AC.GT AC.GT AAAC.GTTT AAAC.GTTT AT.AT AAC.GTT AAC.GTT AAAGGG.CCCTT ATC.GAT AG.CT AAAC.GTTT AC.GT AAC.GTT AAAC.GTTT AC.GT

7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7

88869774 89858058 89878637 89903639 90079044 90114647 90324501 90516163 90565415 90584907 90616372 90631011 90662789 90846684 90969175 91427875 91474386 91667351 91729432 91901853 91901853 91919654 91919654 91919654 92021453 92362054 92683096 92730659 92897324 93051694 93233803 93400284 93884707 93947565 94180897 94687699 94798221 94895983 95078316 95079399 95082400 95264597 95293953 95502799 95625127 95916562 95958167 96053100 96098557 96206500 96248891 96256887 96399563 96447066 96508602 96726824 97109149 97223166 97262852 97355624 97630991 97635996 97685269 97685269 97685269 97685269 97710292 97790835 97829623 97834915 97889539 98024458 98072629 98188931 98231684 98342075 98473315 98631201 98733645 98970687 98989708 99212175 99479000 99593229

88869790 89858073 89878649 89903650 90079054 90114661 90324513 90516173 90565424 90584929 90616390 90631022 90662820 90846702 90969185 91427897 91474397 91667372 91729445 91901867 91901867 91919673 91919673 91919673 92021470 92362067 92683109 92730670 92897339 93051716 93233814 93400306 93884721 93947592 94180909 94687709 94798248 94895994 95078361 95079423 95082426 95264619 95293975 95502809 95625144 95916577 95958202 96053121 96098582 96206516 96248901 96256911 96399585 96447078 96508623 96726833 97109178 97223189 97262872 97355636 97631016 97636018 97685295 97685295 97685295 97685295 97710314 97790848 97829637 97834931 97889548 98024481 98072649 98188956 98231695 98342093 98473338 98631225 98733657 98970701 98989719 99212192 99479013 99593240

5.66667 4 6.5 4 5.5 7.5 6.5 5.5 5 5.75 3.8 3 8 9.5 5.5 5.75 6 11 3.5 3.75 3.75 5 5 5 3.6 7 7 6 4 5.75 3 11.5 7.5 7 6.5 5.5 4.66667 4 11.5 6.25 5.4 4.6 5.75 5.5 6 4 18 11 5.2 5.66667 5.5 12.5 4.6 6.5 5.5 5 5 6 5.25 6.5 6.5 5.75 5.4 5.4 5.4 5.4 5.75 7 3.75 8.5 5 6 5.25 13 4 6.33333 4 8.33333 6.5 3.75 6 6 3.5 6

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000026803 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000002524 CHD2 intron ENSSSCT00000025402 CHD2 intron ENSSSCT00000002524 CHD2 intron ENSSSCT00000027293 CHD2 intron ENSSSCT00000025402 CHD2 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000002520 SLCO3A1 intron ENSSSCT00000002520 SLCO3A1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000002528 . intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000002535 SPTB intron ENSSSCT00000002535 SPTB intron ENSSSCT00000002539HURC1-FNT intron . . intergenic ENSSSCT00000002542 FUT8 intron ENSSSCT00000002542 FUT8 intron ENSSSCT00000002542 FUT8 intron ENSSSCT00000002542 FUT8 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000002545 GPHN intron . . intergenic . . intergenic ENSSSCT00000002548 MPP5 intron . . intergenic . . intergenic ENSSSCT00000002555 ARG2 intron ENSSSCT00000033367 ARG2 intron ENSSSCT00000033225 ARG2 intron ENSSSCT00000034592 ARG2 intron ENSSSCT00000002556 VTI1B intron ENSSSCT00000002558 RDH12 intron ENSSSCT00000002559 ZFYVE26 intron ENSSSCT00000002559 ZFYVE26 intron ENSSSCT00000002559 ZFYVE26 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000023246 . intron ENSSSCT00000023246 . intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000002568 GALNT16 intron . . intergenic ENSSSCT00000002573 KIAA0247 intron

-0.272 0.133 -0.176 2.109 0.17 -0.139 . 0.263 -0.05 -0.089 0.42 . . -0.192 0.188 . -0.067 -0.132 -0.332 . . -0.016 -0.016 -0.016 0.069 0.124 0.132 -0.267 -0.117 0.249 0.065 0.206 0.017 0.086 -0.212 . . 0.034 0.14 0.128 -0.032 0.168 -0.144 0.423 0.051 0.224 . 0.13 0.175 0.55 . -0.001 0.071 0.805 -0.309 0.053 -0.078 0.292 0.147 1.804 . . 0.166 0.166 0.166 0.166 0.079 0.313 0.018 1.948 0.447 0.987 0.213 0.528 . 0.288 0.203 0.152 0.008 . 0.277 0.121 0.009 0.109

. rs792864102 rs793184046 rs790908567 rs786473026 558953 rs7915 799936 rs7867 . . rs793210470 rs791003020 rs792471214 845594 rs7907 rs793679272 rs699852960 679536 rs7893 rs790352624 089171 rs7886 379019 rs7900 rs788303780 rs788303780 528887 rs7885 528887 rs7885 528887 rs7885 rs789947457 . 881758 rs7899 rs792361778 rs791671898 772459 rs7893 rs707767727 566919 rs7915 640369 rs7921 205157 rs7901 242530 rs7899 . rs788867916 . rs786355402 rs786696496 rs787938999 rs792283089 . . 027425 rs7925 rs786505877 rs791724878 996226 rs7911 442291 rs7886 rs792703815 rs792028598 . 068913 rs7864 rs786754665 253148 rs7893 . 394595 rs7932 316828 rs7874 938583 rs7877 . rs789592157 rs789097183 909773 rs7910 909773 rs7910 909773 rs7910 909773 rs7910 rs787945654 . rs793716689 . . rs788389995 rs790646837 353519 rs7878 rs793295010 rs793095329 rs787685449 rs788383406 rs789208301 rs787440619 753526 rs7895 319870 rs7898 rs790286551 .

2 2 2 2 2 2 2 3 4 2 2 2 3 4 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 3 2 2 2 4 2 2 2 2 4 2 2 2 2 2 3 2 2 2 2 2 2 2 2 3 2 2 3 2 2 2 2 2 2 4 2 2 3 2 2 4

AAAT.ATTT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AAAAG.CTTTT AAAC.GTTT AAAC.GTTT AAG.CTT AAG.CTT AATC.GATT AAAAC.GTTTT AC.GT AG.CT AAC.GTT AC.GT AC.GT AG.CT AAAC.GTTT AG.CT AAAC.GTTT AAAAC.GTTTT AAAT.ATTT AC.GT AAAT.ATTT ACG.CGT AAAG.CTTT AAAG.CTTT AG.CT AAAC.GTTT AAT.ATT AG.CT AAC.GTT AAC.GTT AG.CT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AAC.GTT AT.AT AG.CT AT.AT AC.GT AC.GT AAAC.GTTT AAAAC.GTTTT AG.CT AT.AT AC.GT AGGG.CCCT ACAG.CTGT ATC.GAT AG.CT AATT.AATT AAC.GTT AAAAC.GTTTT AG.CT AAAT.ATTT AC.GT AC.GT AG.CT AC.GT AC.GT AAAT.ATTT AAAAT.ATTTT AAAC.GTTT AC.GT AAAAC.GTTTT ATC.GAT AAAT.ATTT AAAAC.GTTTT AAAAT.ATTTT AG.CT AAAG.CTTT AT.AT ATCC.GGAT AAAT.ATTT AT.AT AAACC.GGTTT AG.CT ATC.GAT AT.AT AC.GT AG.CT

7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7

99635434 99747883 100191557 100581328 100630475 100954863 100964944 101256704 101565223 101614710 101716793 101902719 101959191 102006037 102151285 102293591 102293591 102376966 102485566 102867208 102933307 103039479 103059968 103343974 103488918 103731283 103912061 103912061 104105328 104132580 104171241 104238182 104351066 104485589 104536763 105160150 105223764 105286608 105438456 105510467 105921091 105927538 106061611 106128888 106441808 106486373 106948547 106966854 107264924 107335217 107491456 107497310 107524165 107648226 107687053 107761411 107953293 107982121 108444932 108512335 108570840 108648435 109085659 109101711 109126716 109196283 109239454 109262633 109271904 109485184 109648044 109827715 110421806 110492286 110506324 110527683 110552596 110670792 110980357 111398541 111413385 111635306 111885752 111983812

99635453 99747911 100191584 100581363 100630499 100954902 100964958 101256718 101565234 101614723 101716824 101902733 101959209 102006049 102151312 102293608 102293608 102376979 102485591 102867228 102933324 103039507 103059986 103343994 103488941 103731297 103912081 103912081 104105344 104132607 104171260 104238195 104351080 104485605 104536777 105160161 105223795 105286628 105438481 105510476 105921103 105927549 106061623 106128902 106441827 106486400 106948556 106966863 107264935 107335235 107491472 107497329 107524178 107648241 107687074 107761425 107953305 107982141 108444951 108512354 108570851 108648446 109085671 109101726 109126734 109196305 109239466 109262654 109271915 109485202 109648069 109827738 110421822 110492314 110506333 110527696 110552614 110670803 110980389 111398553 111413397 111635318 111885761 111983825

5 5.8 7 9 5 8 3.75 3.75 4 4.66667 8 3 9.5 6.5 9.33333 9 9 7 6.5 10.5 4.5 5.8 4.75 10.5 6 5 5.25 5.25 8.5 7 6.66667 7 5 5.66667 7.5 3 8 4.2 8.66667 5 6.5 6 6.5 7.5 5 5.6 5 5 6 4.75 4.25 6.66667 7 4 7.33333 3 6.5 5.25 10 10 6 6 6.5 4 3.8 5.75 6.5 4.4 4 4.75 5.2 4.8 8.5 7.25 5 3.5 4.75 6 6.6 6.5 4.33333 6.5 5 7

. . intergenic . . intergenic ENSSSCT00000002578 COX16 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000002596 . intron ENSSSCT00000002596 . intron ENSSSCT00000002596 . intron ENSSSCT00000002600 ZFYVE1 intron ENSSSCT00000035550 PSEN1 intron ENSSSCT00000002603 PSEN1 intron . . intergenic ENSSSCT00000031856 . intron . . intergenic ENSSSCT00000002615 . intron ENSSSCT00000002619 ENTPD5 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000002638 PROX2 intron ENSSSCT00000002637 PROX2 intron ENSSSCT00000002646 ACYP1 intron ENSSSCT00000002648 NEK9 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000024345 TTLL5 intron . . intergenic ENSSSCT00000002653 IFT43 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000002675 . intron ENSSSCT00000023660 NOXRED1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000025256 NRXN3 intron . . intergenic . . intergenic ENSSSCT00000031767 . intron ENSSSCT00000031767 . intron ENSSSCT00000031767 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000028622 . intron ENSSSCT00000002683 SEL1L intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

. 0.156 . 0.113 0.161 . . 0.046 -0.034 0.098 -0.07 -0.104 1.106 0.759 . . . -0.154 . 0.163 . 0.614 0.343 0.119 . 0.412 . . . 0.145 0.201 0.176 . . 0.336 . 0.24 . . 0.092 0.123 0.263 -0.228 0.06 -0.025 0.343 0.096 . 0.061 0.575 0.044 0.14 0.091 . 0.021 0.825 -0.027 0.304 1.251 0.354 0.043 0.051 -0.097 0.077 . . -0.033 0.138 0.299 0.231 0.061 . 0.243 0.208 0.34 0.239 0.093 0.298 0.241 -0.089 -0.053 -0.168 . -0.011

rs786767165 012799 rs7891 rs786746458 rs787689704 . rs790911189 rs787807528 rs793304430 rs792455858 rs786681387 869908 rs7872 rs787560337 rs788196086 rs793400304 . rs792497949 rs792497949 . rs788546391 rs792814502 rs789239466 . rs787052657 . rs788321385 442377 rs7893 rs789488458 rs789488458 rs793163244 rs790794499 rs787518222 . 835464 rs7863 186620 rs7880 rs793666281 rs788196704 rs787137915 055095 rs7872 272730 rs7878 753040 rs7879 . rs789807677 rs790311342 181249 rs7918 . rs792772094 . rs787796168 rs790224522 rs792404294 rs788871347 351029 rs7867 rs791814613 rs788839664 520170 rs7873 rs787396856 rs786391036 rs788851024 . 631932 rs7937 rs788032377 rs792963703 822303 rs7878 rs790636503 462148 rs7931 rs793538058 rs793578924 180063 rs7868 517632 rs7867 rs793658461 494039 rs7915 rs792905672 . rs792577578 rs787825149 rs789607714 rs789541216 rs793701691 rs791420423 . . 372690 rs7905 . .

2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 4 2 2 3 2 2 2 3 2 3 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 3 3 2 2 2 2 2 3 2 3 2 2 2 4 2 2 2 2 2 2 3 2 2 2 3

AAAAG.CTTTT AAAC.GTTT AAAT.ATTT AC.GT AAC.GTT AGG.CCT AT.AT AGAGAT.ATCTCT AAAG.CTTT AC.GT AT.AT ACAT.ATGT AC.GT AC.GT AG.CT AT.AT AC.GT AC.GT AAAC.GTTT AAC.GTT ATCC.GGAT AC.GT AT.AT AAAC.GTTT AAAC.GTTT ATC.GAT AAAC.GTTT ACT.AGT AAT.ATT AAAC.GTTT AAT.ATT AT.AT AC.GT AT.AT AG.CT AC.GT AATT.AATT AC.GT AAAC.GTTT AC.GT AAC.GTT AC.GT AC.GT AT.AT AAAC.GTTT AAAC.GTTT AG.CT AG.CT AAAC.GTTT AC.GT AC.GT AGG.CCT AAACC.GGTTT AAAAC.GTTTT AG.CT AC.GT AATG.CATT AATC.GATT AAAG.CTTT AGG.CCT AAT.ATT AC.GT AG.CT AAAG.CTTT AAAC.GTTT AAC.GTT AC.GT AAAT.ATTT AAAACT.AGTTTT AAAAT.ATTTT AG.CT AAAC.GTTT AAT.ATT AAT.ATT AAT.ATT AG.CT ATCC.GGAT AG.CT AC.GT AG.CT AAAAAC.GTTTTT AAAAT.ATTTT AAAGC.GCTTT AAAAC.GTTTT

7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7

112392545 112414758 112490695 112779082 112810611 112896847 112999679 113009721 113058920 113169654 113205023 113276446 113376520 113382670 113400021 113514496 113560755 113593443 113632201 113695692 113748721 113778208 113786683 113979561 114001440 114062616 114144290 114390552 114461852 114516062 114516217 114626474 114711531 114822722 114863853 114966101 115123899 115142849 115152852 115263773 115438971 115529049 115623626 115743575 115791411 115833559 115878903 115993296 116048588 116175804 116222792 116226125 116282641 116571023 116667021 116668501 116685255 116915865 117244598 117287343 117336684 117338904 117719086 117755683 117773459 117857363 118201819 118217558 118325546 118357534 118470902 118508614 118515285 118777397 118816640 118929457 118934781 119282846 119338904 119350502 119386867 119631316 119858385 119936516

112392563 112414784 112490711 112779091 112810624 112896858 112999688 113009758 113058943 113169665 113205033 113276476 113376534 113382698 113400032 113514505 113560765 113593455 113632215 113695713 113748741 113778230 113786697 113979580 114001458 114062634 114144312 114390563 114461869 114516092 114516228 114626486 114711555 114822733 114863873 114966110 115123920 115142859 115152866 115263782 115438983 115529064 115623653 115743586 115791422 115833573 115878915 115993308 116048607 116175813 116222807 116226141 116282664 116571055 116667031 116668514 116685279 116915877 117244615 117287356 117336704 117338920 117719107 117755697 117773473 117857384 118201829 118217574 118325566 118357557 118470911 118508636 118515302 118777416 118816654 118929471 118934819 119282860 119338915 119350511 119386887 119631343 119858415 119936550

3.8 6.75 4.25 5 4.66667 4 5 6.33333 6 6 5.5 7.75 7.5 14.5 6 5 5.5 6.5 3.75 7.33333 5.25 11.5 7.5 5 4.75 6.33333 5.75 4 6 7.75 4 6.5 12.5 6 10.5 5 5.5 5.5 3.75 5 4.33333 8 14 6 3 3.75 6.5 6.5 5 5 8 5.66667 4.8 6.6 5.5 7 6.25 3.25 4.5 4.66667 7 8.5 11 3.75 3.75 7.33333 5.5 4.25 3.5 4.8 5 5.75 6 6.66667 5 7.5 9.75 7.5 6 5 3.5 5.6 6.2 7

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000002692 ENSSSCT00000002692 ENSSSCT00000002692 ENSSSCT00000002694 ENSSSCT00000002697 . ENSSSCT00000022230 . ENSSSCT00000002698 ENSSSCT00000002698 ENSSSCT00000002698 ENSSSCT00000002698 ENSSSCT00000002700 ENSSSCT00000002700 ENSSSCT00000002700 ENSSSCT00000002701 ENSSSCT00000002702 ENSSSCT00000002702 ENSSSCT00000002702 . . ENSSSCT00000002706 ENSSSCT00000002706 . . . . . . .

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . KCNK10 KCNK10 KCNK10 PTPN21 TTC8 . U6 . FOXN3 FOXN3 FOXN3 FOXN3 EFCAB11 EFCAB11 EFCAB11 . KCNK13 KCNK13 KCNK13 . . . . . . . . . . .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intergenic promoter intergenic intron intron intron intron intron intron intron intron intron intron intron intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic

-0.102 . -0.008 0.046 0.427 -0.126 0.022 . -0.105 -0.119 -0.21 0.216 -0.217 -0.006 -0.171 0.382 -0.194 -0.124 0.116 -0.122 0.299 0.012 0.016 0.719 0.198 0.071 -0.258 0.308 -0.162 . . 0.01 -0.043 0.029 -0.25 -0.121 -0.124 -0.233 0.19 -0.028 -0.052 -0.189 -0.004 . -0.029 0.134 -0.047 1.763 0.07 -0.18 0.82 . 0.413 0.237 0.044 0.158 0.096 . 0.117 -0.081 . . 0.015 . -0.076 0.28 -0.184 . 0.566 -0.134 . . -0.089 -0.031 -0.017 0.256 -0.017 0.212 0.038 -0.163 . . . 0.194

636768 rs7877 rs791879394 987364 rs7924 . rs792157222 032066 rs7938 rs786480695 rs792753953 rs788154398 rs786503151 853156 rs7910 114678 rs7889 873812 rs7900 602407 rs7869 rs789204045 rs793804263 rs792277110 . rs786869494 rs791099855 490964 rs7871 . 621451 rs7903 rs792907056 rs791030091 014053 rs7875 rs790293758 rs791730855 rs792111292 rs787469654 . rs792054778 . rs698526009 rs709745074 rs787754338 783162 rs7889 rs792222358 rs787201727 . 861830 rs7864 rs791098103 504897 rs7877 700884 rs7873 . 173780 rs7901 139396 rs7914 rs793450837 rs786949644 rs787436239 rs791571865 . 709802 rs7884 418379 rs7862 872887 rs7890 . . rs789633884 rs787902370 . 471442 rs7873 rs791206783 rs793640726 rs791884789 533941 rs7897 rs789227671 rs786623831 rs791390270 rs787517863 rs788311059 . rs792697160 rs792715431 rs789508161 rs788860747 rs790085272 rs793377269 rs786430076 rs791587315 rs789806469 971690 rs7863 rs789839651 182649 rs7937 134658 rs7924

2 2 2 3 4 2 2 2 2 2 2 2 2 2 2 2 2 5 2 3 2 4 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 4 3 2 2 2 2 2

AG.CT AAAT.ATTT AAAC.GTTT AGC.GCT AT.AT AAAAT.ATTTT AAAC.GTTT AC.GT ATCC.GGAT AC.GT AC.GT AAAG.CTTT AG.CT AAAG.CTTT AC.GT AG.CT AAAG.CTTT AATG.CATT AAAGC.GCTTT AC.GT AC.GT AAC.GTT AC.GT AC.GT AAAG.CTTT AC.GT AT.AT AT.AT AAC.GTT AAAC.GTTT AAC.GTT AAT.ATT AAAAC.GTTTT AAAAT.ATTTT AC.GT AC.GT AC.GT AC.GT ATCC.GGAT AG.CT AGAT.ATCT AAAT.ATTT AC.GT AAAC.GTTT AC.GT AAC.GTT AAGG.CCTT AAAT.ATTT AAGG.CCTT AG.CT AAAC.GTTT AAAC.GTTT AC.GT AT.AT AC.GT AC.GT AAAAT.ATTTT AAAAAC.GTTTTT AAC.GTT AC.GT AGC.GCT AAAC.GTTT AAT.ATT AG.CT AAAAT.ATTTT AAAT.ATTT AG.CT AAGG.CCTT AC.GT AAAAAC.GTTTTT AC.GT AAAAT.ATTTT AAAAT.ATTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AC.GT AAAG.CTTT AAC.GTT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT

7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8

120112399 120194805 120209400 120224820 120225142 120284062 120381144 120490204 120649680 120778886 120781867 120861596 120938954 121445941 121508309 121602806 121643942 122917333 123009632 123202464 123615942 123686055 123748341 123993719 124052611 124053705 124063996 124385943 124488720 124796207 124814030 124938215 125013031 125071859 125130651 125172820 125647395 125670677 125677186 126139060 126208243 126544521 126774510 127299998 127559636 127741811 127929222 128030543 128052763 128272133 128447835 128888878 129025743 129066331 129072132 129118119 129178625 129368763 129992918 130495363 130796553 131042022 133000423 133514794 133564107 133969000 134204752 134364074 134431791 103716 162382 573418 573418 611273 611273 957403 1213801 1504872 2281887 2552390 2724824 2743168 4022811 4097828

120112408 120194821 120209422 120224840 120225158 120284078 120381161 120490214 120649697 120778903 120781878 120861614 120938976 121445953 121508319 121602821 121643956 122917349 123009661 123202482 123615952 123686071 123748353 123993734 124052634 124053716 124064005 124385952 124488731 124796231 124814049 124938227 125013051 125071877 125130660 125172830 125647406 125670691 125677199 126139084 126208259 126544542 126774526 127300012 127559649 127741830 127929237 128030556 128052782 128272145 128447849 128888900 129025752 129066341 129072142 129118133 129178654 129368785 129992933 130495372 130796565 131042048 133000443 133514827 133564132 133969017 134204766 134364091 134431813 103741 162404 573437 573437 611297 611297 957423 1213820 1504886 2281902 2552407 2724847 2743184 4022829 4097839

5 4.25 5.75 7 8.5 3.4 4.5 5.5 4.5 9 6 4.75 11.5 3.25 5.5 8 3.75 4.25 6 9.5 5.5 5.66667 6.5 8 6 6 5 5 4 6.25 6.66667 4.33333 4.2 3.8 5 5.5 6 7.5 3.5 12.5 4.25 5.5 8.5 3.75 7 6.66667 4 3.5 5 6.5 3.75 5.75 5 5.5 5.5 7.5 6 3.83333 5.33333 5 4.33333 6.75 7 17 5.2 4.5 7.5 4.5 11.5 4.33333 11.5 4 4 6.25 6.25 5.25 5 7.5 4 6 4.8 4.25 4.75 3

ENSSSCT00000002714 FBLN5 intron ENSSSCT00000002715 TRIP11 intron ENSSSCT00000002715 TRIP11 promoter ENSSSCT00000002716 ATXN3 cds ENSSSCT00000002716 ATXN3 intron . . intergenic . . intergenic ENSSSCT00000002720 SLC24A4 intron . . intergenic . . intergenic ENSSSCT00000002722 . intron ENSSSCT00000002725 GOLGA5 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000002757 SERPINA5 intron . . intergenic . . intergenic ENSSSCT00000022914 DICER1 intron . . intergenic ENSSSCT00000002772 CLMN intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000002780 ATG2B intron ENSSSCT00000002780 ATG2B intron ENSSSCT00000002783 PAPOLA intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000002786 SETD3 intron ENSSSCT00000002787 CCNK intron ENSSSCT00000002788 CYP46A1 intron . . intergenic ENSSSCT00000002802 CDC42BPB promoter . . intergenic . . intergenic ENSSSCT00000002805 RCOR1 intron ENSSSCT00000002805 RCOR1 intron ENSSSCT00000002805 RCOR1 intron . . intergenic ENSSSCT00000002821 PPP2R5C intron . . intergenic . . intergenic ENSSSCT00000002836 TDRD9 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000002907 EFHC1 intron . . intergenic ENSSSCT00000024099 . intron ENSSSCT00000002916 ICK intron ENSSSCT00000030851 PCGF3 intron ENSSSCT00000026976 MFSD7 intron ENSSSCT00000009498 NELFA intron ENSSSCT00000009501 POLN intron ENSSSCT00000009498 NELFA intron ENSSSCT00000009501 POLN intron . . intergenic ENSSSCT00000009510 ADD1 intron ENSSSCT00000009515HUNTINGTI intron . . intergenic ENSSSCT00000009528 C4orf50 intron . . intergenic . . intergenic . . intergenic . . intergenic

0.745 0.148 0.126 0.269 0.191 0.05 . . -0.046 -0.24 0.389 0.548 -0.174 . . . . -0.354 . -0.035 -0.022 0.116 -0.361 -0.423 . . . 0.002 . 1.67 0.311 -0.461 -0.176 . -0.145 -0.45 -0.633 . . -0.277 . -0.086 0.078 0.072 1.584 -0.215 -0.188 . 0.065 -0.237 0.217 -0.581 -0.094 2.489 2.111 . . . 0 . . -0.123 . . -0.003 . 0.165 0.146 0.1 . 0.623 -0.126 -0.126 . . -0.047 . 0.937 -0.254 -0.034 -0.21 . . -0.354

. rs786789505 rs792173378 rs790699493 rs789531793 rs792247595 354653 rs7872 rs788896225 651673 rs7885 rs790480972 rs792259932 777680 rs7867 rs787053616 624888 rs7925 rs707111398 rs788305062 rs792292088 rs793655442 rs791438123 . . rs791349693 rs790275812 rs793351392 rs791943235 rs788566625 . . rs789950489 638726 rs7913 rs792491171 rs792292858 433566 rs7932 rs786290760 rs789095348 rs788082700 . 195450 rs7901 . . rs792044989 094609 rs7908 rs786974274 rs789334067 799250 rs7893 rs786571678 . . rs789299568 rs790335550 rs786889822 rs791110180 rs790845321 . rs792203310 . rs788332471 rs792026412 127888 rs7873 rs789054591 rs786330619 rs697285782 rs788679408 686838 rs7937 rs791577872 855506 rs7906 320582 rs7883 . rs792987054 801085 rs7879 956902 rs7885 978410 rs7915 978410 rs7915 638194 rs7918 638194 rs7918 rs788408460 rs793745503 525245 rs7881 . rs789321351 235476 rs7883 rs792868142 . rs792038696

2 2 2 2 3 2 2 2 2 3 2 2 3 2 2 2 2 2 2 2 2 2 3 2 3 5 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 3 2 2 2 2 2 2 2 3 2 2 2 3 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 4 3 2 2

AC.GT AAAG.CTTT ACAT.ATGT AATG.CATT AG.CT AC.GT AAAC.GTTT AAAC.GTTT AC.GT AAC.GTT AT.AT AAAT.ATTT AG.CT AAAC.GTTT AC.GT AAACC.GGTTT AAAAT.ATTTT AC.GT AAC.GTT AT.AT AC.GT AC.GT AT.AT AAAAC.GTTTT ATC.GAT AAAAAT.ATTTTT AATG.CATT ATC.GAT AC.GT AATG.CATT AT.AT AAAAT.ATTTT AC.GT AT.AT AC.GT AAAC.GTTT AAAG.CTTT ATC.GAT AAAC.GTTT AG.CT AAAT.ATTT AT.AT AC.GT ATCC.GGAT AT.AT AAC.GTT AAAC.GTTT AG.CT AAAC.GTTT AG.CT AGAGG.CCTCT AC.GT AAAT.ATTT AAAAT.ATTTT AAAC.GTTT AAAC.GTTT AATG.CATT AAAC.GTTT AAG.CTT AT.AT AG.CT AC.GT AT.AT AAAG.CTTT AG.CT AG.CT AT.AT AC.GT AAAG.CTTT AG.CT AAG.CTT AAAAC.GTTTT AATG.CATT AT.AT AT.AT AAT.ATT AC.GT AC.GT AAC.GTT AAAT.ATTT AAAG.CTTT AAAC.GTTT AG.CT AG.CT

8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8

4258208 4727635 4821957 4899252 5168439 5366570 5392620 5458392 5566139 5566921 6000740 6011302 6080014 6227302 6560000 6605551 6627481 7073483 7330998 7520519 7635693 7783158 7897135 7910390 7978829 7984825 8077223 8125259 8131414 8356983 8809172 8852903 8857301 8861207 8901442 8920975 8935103 8962885 9257368 9278730 9285613 9469125 9640439 9786566 9867748 10538117 10548554 10574320 10616020 10657081 10739734 10959894 11142113 11242101 11279596 11477368 11519134 11520864 11819573 12278627 12365825 12548122 12568096 12777855 13073070 13136208 13300914 13418911 13435501 13559638 14112921 14125969 14286018 14332046 14412006 14549699 14662630 14792846 14894805 14980246 15018840 15194638 15407248 15481343

4258217 4727670 4821971 4899281 5168449 5366580 5392641 5458414 5566153 5566937 6000756 6011320 6080023 6227331 6560015 6605581 6627499 7073498 7331009 7520537 7635705 7783168 7897144 7910408 7978843 7984842 8077245 8125271 8131430 8357009 8809184 8852920 8857315 8861217 8901451 8920994 8935120 8962896 9257389 9278751 9285632 9469138 9640448 9786583 9867757 10538141 10548576 10574333 10616033 10657095 10739760 10959910 11142131 11242125 11279610 11477386 11519151 11520886 11819584 12278636 12365856 12548133 12568106 12777879 13073082 13136234 13300924 13418923 13435517 13559673 14112935 14125999 14286044 14332055 14412022 14549717 14662640 14792862 14894818 14980260 15018863 15194655 15407260 15481352

5 9 3.75 7.5 5.5 5.5 5.5 5.75 7.5 5.66667 8.5 4.75 5 7.5 8 6.2 3.8 8 4 9.5 6.5 5.5 5 3.8 5 3 5.75 4.33333 8.5 6.75 6.5 3.6 7.5 5.5 5 5 4.5 4 5.5 11 5 7 5 4.5 5 8.33333 5.75 7 3.5 7.5 5.4 8.5 4.75 5 3.75 4.75 4.5 5.75 4 5 16 6 5.5 6.25 6.5 13.5 5.5 6.5 4.25 18 5 6.2 6.75 5 8.5 6.33333 5.5 8.5 4.66667 3.75 6 4.5 6.5 5

ENSSSCT00000009541 ABLIM2 intron . . intergenic . . intergenic ENSSSCT00000023202 STK32B intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000031128 . intron ENSSSCT00000031128 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009556 CPEB2 intron ENSSSCT00000009559 CC2D2A intron . . intergenic ENSSSCT00000009562 FBXL5 intron . . intergenic . . intergenic ENSSSCT00000009565 CD38 intron ENSSSCT00000009568 PROM1 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000025105 LDB2 intron ENSSSCT00000025105 LDB2 intron ENSSSCT00000025105 LDB2 intron . . intergenic . . intergenic ENSSSCT00000024457 CLRN2 intron . . intergenic ENSSSCT00000009570 NCAPG intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009572 SLIT2 intron ENSSSCT00000030135 KCNIP4 intron

-1.261 . 0.022 -0.107 -0.377 -0.123 . -0.24 . . . . -0.33 . -0.012 0.148 -0.169 -0.384 -0.268 . 0.047 0.022 . . . -0.139 -0.06 -0.236 0.446 -0.129 -0.001 -0.338 -0.3 . 0.015 . -0.085 -0.067 -0.187 -0.121 0.128 0.081 -0.155 -0.021 -0.04 -0.038 . . 0.352 . -0.115 -0.069 . -0.403 . -0.16 -0.038 0.155 -0.24 . 0.062 0.794 0.083 -0.14 -0.033 0.223 -0.084 0.096 . 0.304 -0.27 . -0.281 -0.153 -0.002 -0.049 0.035 0.215 -0.008 . 1.185 0.861 -0.212 .

. rs792746792 . 770211 rs7936 144858 rs7878 . 731574 rs7900 rs793644552 . . . rs788046244 rs792649347 685884 rs7863 rs788437266 rs786246493 rs790674358 rs789145751 . 762279 rs7890 rs793072992 . rs793297160 933686 rs7868 . 284011 rs7890 rs790678444 . . 100683 rs7904 . rs790981685 rs791776419 . rs788436326 . 812308 rs7936 . rs786243889 rs790807686 rs790897552 rs786481795 rs790195973 . rs789586651 876686 rs7908 rs789722395 rs788624803 rs791014019 rs789562259 rs787578552 rs791637446 rs788538426 rs793725577 rs793720867 462292 rs7869 . rs792508393 377247 rs7913 . rs788705339 . rs791056354 694587 rs7926 rs792158817 rs792267914 rs790869032 rs790111261 290605 rs7901 rs791942511 . rs792783936 rs788597653 rs788325070 . rs791147045 570377 rs7932 . rs787181271 rs787451274 rs789204400 336823 rs7925 286562 rs7867 .

2 3 2 2 2 2 2 2 3 4 2 2 2 2 2 2 2 5 2 2 2 2 2 2 2 2 2 2 5 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 3 2 3 2 2 2 3 4 2 2 2 2 3 3 2 3 2 2 2 2 2 2 2 2 3 2 2 2 2 3 2 2 2 2 2

AG.CT AAAC.GTTT AAAC.GTTT AG.CT AAAAC.GTTTT AAAT.ATTT AAAAAC.GTTTTT AAC.GTT AT.AT AAT.ATT AAAAC.GTTTT AAAAAC.GTTTTT AC.GT AC.GT AAAT.ATTT AAAT.ATTT AT.AT AC.GT AG.CT AC.GT AC.GT AAC.GTT AT.AT AGATAT.ATATCT ATC.GAT AAT.ATT AAC.GTT AT.AT ATC.GAT AAAC.GTTT AAAT.ATTT AC.GT AC.GT AC.GT AAC.GTT AT.AT ACC.GGT AAT.ATT AT.AT AAAC.GTTT AGG.CCT AAG.CTT AG.CT AC.GT AAAAAC.GTTTTT AG.CT AAAAC.GTTTT AAT.ATT AT.AT AAGG.CCTT ACC.GGT AAAC.GTTT AAT.ATT AAC.GTT AT.AT AAAC.GTTT AT.AT AT.AT AGGG.CCCT AAC.GTT AAAAC.GTTTT ACAT.ATGT AAAC.GTTT AC.GT AT.AT AAT.ATT AT.AT AC.GT AAAC.GTTT AAAT.ATTT AAAC.GTTT AAAC.GTTT AC.GT AG.CT AAAT.ATTT AAG.CTT AC.GT AG.CT AGAT.ATCT AG.CT AAAC.GTTT AAC.GTT AAAAC.GTTTT AC.GT

8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8

15481343 15495103 15495103 15512533 15515348 15569492 15744933 16007359 16009913 16152778 16448889 16486685 16576985 16664700 16751030 16817119 17014834 17068274 17324914 17364014 17390595 17391399 17481785 17505744 17578811 17578906 17626645 17664634 17806984 17817029 17832309 17959664 18160846 18237884 18258098 18307235 18396171 18580959 18732503 18901808 18978151 19008672 19323602 19349382 19392159 19513361 20004343 20237194 20296437 20321129 20347052 20429002 20469968 20761461 20780429 20813320 20905891 21071268 21189686 21539138 21656833 21754505 21894215 22079162 22133785 22188500 22337656 22379794 22399964 22674705 22955070 23063662 23082991 23083688 23104894 23161014 23270478 23272861 23301252 23303803 23311129 23338330 23342321 23485109

15481352 15495117 15495117 15512544 15515366 15569510 15744954 16007373 16009926 16152790 16448914 16486707 16576999 16664715 16751045 16817139 17014845 17068300 17324928 17364028 17390613 17391414 17481800 17505776 17578825 17578918 17626658 17664643 17807009 17817043 17832323 17959676 18160864 18237895 18258110 18307250 18396186 18580983 18732519 18901822 18978165 19008696 19323614 19349396 19392196 19513370 20004366 20237210 20296448 20321154 20347065 20429020 20469980 20761474 20780440 20813342 20905901 21071278 21189711 21539156 21656854 21754517 21894227 22079203 22133794 22188515 22337665 22379803 22399985 22674727 22955094 23063678 23083007 23083698 23104916 23161030 23270488 23272873 23301278 23303817 23311152 23338346 23342339 23485125

5 3.75 3.75 6 3.8 4.75 3.66667 5 7 4.33333 5.2 3.83333 7.5 8 4 5.25 6 13.5 7.5 7.5 9.5 5.33333 8 5.5 5 4.33333 4.66667 5 8.66667 3.75 3.75 6.5 9.5 6 4.33333 8 5.33333 8.33333 8.5 3.75 5 8.33333 6.5 7.5 6.33333 5 4.8 5.66667 6 6.5 4.66667 4.75 4.33333 4.66667 6 5.75 5.5 5.5 6.5 6.33333 4.4 3.25 3.25 21 5 5.33333 5 5 5.5 5.75 6.25 4.25 8.5 5.5 5.75 5.66667 5.5 6.5 6.75 7.5 6 5.66667 3.8 8.5

ENSSSCT00000031079 ENSSSCT00000030135 ENSSSCT00000031079 ENSSSCT00000030135 ENSSSCT00000030135 ENSSSCT00000030135 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000009580 . . . ENSSSCT00000029731 . . . . . . . . ENSSSCT00000023054 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

KCNIP4 KCNIP4 KCNIP4 KCNIP4 KCNIP4 KCNIP4 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . DHX15 . . . . . . . . . . . . RBPJ . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

. . . 0.015 -0.17 . -0.045 . -0.191 -0.149 0.044 -0.255 . -0.165 -0.009 0.274 . -0.064 1.491 0.148 -0.012 0.53 0.107 -0.08 -0.071 -0.165 -0.243 -0.072 -0.046 -0.148 0.134 0.674 0.729 1.872 0.045 -0.184 -0.087 0.091 -0.043 -0.271 1.254 0.805 -0.269 0.095 . . . . -0.024 . 0.046 0.171 0.129 0.077 0.107 0.219 . -0.058 -0.155 -0.097 -0.228 0.099 -0.114 -0.091 . 0.068 0.015 0.043 -0.31 -0.139 . 0.074 0.301 -0.199 -0.066 . 0.02 . -0.223 -0.004 0.301 -0.212 0.025 .

. rs787261368 rs787261368 rs793019907 rs786981797 . . . rs791720466 960357 rs7872 rs788953206 rs790223651 . . rs791634499 rs789639713 rs792813563 rs691364496 rs793174631 996288 rs7869 . 941426 rs7907 rs788694877 . . . 250918 rs7866 . . 609814 rs7912 241872 rs7886 116669 rs7898 rs789859480 rs792177477 rs787417637 . rs702842129 rs790156901 . rs793479569 . rs791012265 rs791129488 rs786377930 rs792756504 rs790471182 rs788829420 rs790676517 rs786713885 . rs792307824 098077 rs7889 150810 rs6904 rs791846051 rs787684610 rs791568598 . rs789821039 353653 rs7881 640445 rs7870 rs790917211 rs789773229 rs786890984 970618 rs7927 . . . rs793753928 rs792277616 rs713493605 143056 rs7883 093149 rs7916 . rs708205747 396527 rs7882 055530 rs7927 . 159799 rs7893 609091 rs7899 rs793085390 095233 rs7909 853831 rs7930 627873 rs7926 150187 rs7891

2 2 2 3 2 2 2 4 2 2 2 2 3 3 3 2 2 3 3 2 4 2 2 2 2 2 2 2 2 2 2 3 2 2 2 3 2 2 2 2 2 2 3 2 3 2 2 2 2 2 2 2 3 2 2 2 4 2 2 2 2 2 4 3 3 2 2 2 3 4 2 2 3 2 2 2 2 3 2 2 2 2 2 2

AAAC.GTTT AAAT.ATTT AC.GT AC.GT AAAAC.GTTTT AAAT.ATTT AT.AT AAAT.ATTT AG.CT AG.CT AAAC.GTTT AAT.ATT AT.AT AAAC.GTTT AC.GT AC.GT AC.GT AT.AT AC.GT AAT.ATT AAG.CTT AT.AT AC.GT AAAG.CTTT AC.GT AT.AT AAAC.GTTT AG.CT AC.GT AAAC.GTTT AAAC.GTTT AAC.GTT AATG.CATT AAAAC.GTTTT AG.CT AAAAC.GTTTT AAT.ATT AT.AT AAC.GTT AAAT.ATTT AAAC.GTTT AAAT.ATTT AG.CT AAAT.ATTT AAC.GTT AC.GT AAAT.ATTT AC.GT AT.AT AAC.GTT AC.GT AT.AT AAAC.GTTT AC.GT AT.AT AAAAC.GTTTT AC.GT AG.CT AATG.CATT AC.GT AC.GT AC.GT AC.GT AAAC.GTTT AAG.CTT AC.GT AG.CT AAT.ATT AC.GT AATG.CATT AAC.GTT AT.AT AC.GT AG.CT AAC.GTT AC.GT AAGAGG.CCTCT AG.CT AAGG.CCTT ACAT.ATGT AAG.CTT AC.GT AAC.GTT AAC.GTT

8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8

23530389 23531315 23533563 23721038 23728779 23836080 24284282 24285174 24309288 24397961 24423738 24434067 24458867 24460720 24614928 24660213 25037044 25201314 25226314 25284207 25308246 25377397 26081711 26252523 26283491 26512327 26516911 26532775 26579419 26617082 26630224 26631069 26819972 26982051 26987922 26991507 27059365 27086197 27101102 27140914 27305404 27421998 27425782 27497564 27714066 27897672 28030790 28032165 28074785 28104872 28189373 28220015 28287514 28670727 28735653 28815887 28989998 29262424 29458152 29670551 29670551 29670551 29670551 29859855 29904521 30137629 30404161 30425136 30513717 30616182 30621743 30645871 30690255 30719326 30797202 31048391 31099761 31348231 31370576 31426974 31437919 31477779 31477904 31487971

23530419 23531330 23533575 23721051 23728816 23836098 24284292 24285198 24309297 24397973 24423760 24434084 24458876 24460737 24614959 24660222 25037058 25201331 25226323 25284235 25308262 25377406 26081723 26252536 26283505 26512336 26516942 26532789 26579435 26617111 26630250 26631082 26819983 26982074 26987932 26991535 27059378 27086206 27101124 27140927 27305423 27422011 27425792 27497577 27714083 27897684 28030811 28032174 28074800 28104895 28189387 28220026 28287531 28670741 28735662 28815910 28990009 29262433 29458169 29670565 29670565 29670565 29670565 29859875 29904534 30137642 30404171 30425170 30513730 30616193 30621756 30645882 30690265 30719338 30797219 31048404 31099778 31348243 31370610 31427002 31437938 31477794 31477917 31487984

7.75 4 6.5 7 7.6 4.75 5.5 6.25 5 6.5 5.75 6 5 4.5 16 5 7.5 9 5 9.66667 5.66667 5 6.5 3.5 7.5 5 8 7.5 8.5 7.5 6.75 4.66667 3 4.8 5.5 5.8 4.66667 5 7.66667 3.5 5 3.5 5.5 3.5 6 6.5 5.5 5 8 8 7.5 6 4.5 7.5 5 4.8 6 5 4.5 7.5 7.5 7.5 7.5 5.25 4.66667 7 5.5 11.6667 7 3 4.66667 6 5.5 6.5 6 7 3 6.5 8.75 7.25 6.66667 8 4.66667 4.66667

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009593 ARAP2 intron . . intergenic ENSSSCT00000009594H242-305H5 promoter ENSSSCT00000035368H242-305H5 promoter ENSSSCT00000034516H242-305H5 promoter ENSSSCT00000034680H242-305H5 promoter . . intergenic . . intergenic . . intergenic ENSSSCT00000009595 KIAA1239 intron . . intergenic ENSSSCT00000009596 C4orf19 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009598 PGM2 intron . . intergenic ENSSSCT00000009599 TBC1D1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

-0.262 0.729 . -0.22 -0.002 0.026 -0.141 0.045 -0.053 -0.057 0.472 -0.106 0.064 -0.088 0.281 0.72 0.557 -0.08 -0.07 0.036 0.426 0.161 . 0.035 -0.27 -0.072 . -0.016 -0.156 -0.126 . . . -0.054 -0.035 -0.051 -0.124 -0.162 -0.039 0.047 . -0.219 . -0.012 . . . . . . 0.045 . 0.176 -0.098 . -0.006 . -0.026 0.05 -0.058 -0.058 -0.058 -0.058 0.077 0.133 0.213 3.067 1.816 -0.036 . 0.165 0.066 0.228 -0.232 0.214 -0.01 -0.335 0.117 0.499 0.235 0.035 -0.007 -0.125 0.037

rs788232629 157759 rs7900 rs790756805 rs786453055 rs788537010 882235 rs7881 456301 rs7893 200550 rs7876 . 546995 rs7886 rs792785548 647135 rs7932 . 631541 rs7936 914137 rs7870 rs787476598 556209 rs7872 rs790811561 rs788683554 585941 rs7881 rs788333189 rs793755109 rs792789401 754489 rs7894 . rs701813559 rs793586506 rs789979221 . 470801 rs7906 rs786725408 rs792214389 rs793597849 503331 rs7875 . rs786595901 rs792864442 999843 rs7887 395958 rs7894 rs789346556 rs790881240 rs788753815 106438 rs7921 724855 rs7864 rs786228671 689677 rs7921 rs791065062 rs790670413 rs789546675 868925 rs7903 671928 rs7903 rs790355837 rs792119380 . 817601 rs7886 rs790311431 rs787911091 rs790734834 . 914255 rs7930 914255 rs7930 914255 rs7930 914255 rs7930 105527 rs7896 rs792788226 rs787466548 891296 rs7906 rs787320774 rs788478452 . 228804 rs7912 rs787801308 rs791042953 rs789935046 584179 rs7907 . rs787542011 148382 rs7900 663162 rs7879 011836 rs7868 rs791713743 rs788426590 rs793507078 rs692826570

5 2 2 2 2 2 3 2 2 4 2 2 2 2 2 2 2 2 2 2 2 4 2 2 3 2 2 2 2 3 2 2 3 2 3 2 3 2 4 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 3 2 2 2 2 3 2 3 2 3 2 2 2 4 2 4

AGG.CCT AT.AT AC.GT AATAT.ATATT AC.GT AC.GT AC.GT AAT.ATT AAAC.GTTT AT.AT AC.GT AAAC.GTTT AC.GT AG.CT AGG.CCT AC.GT AAAC.GTTT AC.GT AG.CT AG.CT AT.AT AT.AT AAAC.GTTT AAAC.GTTT AAAAG.CTTTT AG.CT AT.AT AAG.CTT AC.GT ACAT.ATGT AG.CT AAC.GTT AAAC.GTTT AT.AT AAAC.GTTT AG.CT AAAAC.GTTTT AC.GT AAAAC.GTTTT AAGG.CCTT AAAAT.ATTTT AT.AT AT.AT AG.CT AAAC.GTTT AC.GT AC.GT AG.CT AT.AT AAAAC.GTTTT AAAC.GTTT AG.CT AAAAT.ATTTT AC.GT AT.AT AT.AT AC.GT AAC.GTT AG.CT AT.AT ATC.GAT AATC.GATT AAAAAC.GTTTTT AT.AT AT.AT AC.GT AAAC.GTTT AT.AT AC.GT AAAG.CTTT AAAG.CTTT AAC.GTT AAAT.ATTT AT.AT AAG.CTT AC.GT AAAC.GTTT AG.CT AAAAAT.ATTTTT AC.GT AAAC.GTTT AAAC.GTTT AAAC.GTTT AC.GT

8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8

31554934 31715709 31870106 31995419 32082099 32082099 32212752 32320975 32526231 32638552 32646037 33002359 33046700 33101632 33129610 33165232 33209987 33247471 33291939 33291939 33454763 33717305 33743781 33824272 33966283 33967611 34043070 34136062 34166939 34198554 34262260 34263337 34352923 34647687 34731390 34908915 34966860 35394263 35533861 35778458 36297265 36833344 36993685 37010054 37187549 37318846 37358312 37405184 37422209 37569781 37727424 37757196 37844429 37874496 37875857 37999636 38003387 38025001 38259958 38274854 38313655 38325328 38432853 38440884 38545155 38635356 38659226 38801343 38941150 38953467 39007346 39213325 39331878 39522402 39566798 39571500 39650077 39667037 39711032 40004049 40113837 40113837 40113837 40299614

31554946 31715734 31870118 31995443 32082110 32082110 32212761 32320991 32526245 32638569 32646051 33002379 33046717 33101641 33129629 33165270 33210016 33247482 33291951 33291951 33454782 33717314 33743808 33824291 33966303 33967622 34043094 34136075 34166951 34198575 34262273 34263351 34352946 34647696 34731416 34908924 34966881 35394275 35533876 35778482 36297294 36833370 36993700 37010066 37187560 37318857 37358324 37405194 37422220 37569800 37727450 37757205 37844452 37874518 37875868 37999647 38003405 38025020 38259969 38274877 38313673 38325358 38432882 38440894 38545171 38635383 38659245 38801357 38941160 38953483 39007360 39213342 39331895 39522413 39566817 39571538 39650091 39667047 39711050 40004063 40113851 40113851 40113851 40299630

4.33333 13 6.5 5 6 6 5 5.66667 3.75 9 7.5 5.25 9 5 6.66667 19.5 7.5 6 6.5 6.5 10 5 7 5 4.2 6 12.5 4.66667 6.5 5.5 7 5 6 5 6.75 5 4.4 6.5 3.2 6.25 6 13.5 8 6.5 3 6 6.5 5.5 6 4 6.75 5 4.8 11.5 6 6 9.5 6.66667 6 12 6.33333 7.75 5 5.5 8.5 14 5 7.5 5.5 4.25 3.75 6 4.5 6 6.66667 19.5 3.75 5.5 3.16667 7.5 3.75 3.75 3.75 8.5

. . intergenic ENSSSCT00000009611 FAM114A1 intron ENSSSCT00000009613 . intron . . intergenic ENSSSCT00000009615 WDR19 intron ENSSSCT00000027462 WDR19 intron ENSSSCT00000009614 . intron ENSSSCT00000022874 LIAS intron . . intergenic ENSSSCT00000030457 UBE2K intron ENSSSCT00000030457 UBE2K intron ENSSSCT00000009621 RHOH intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000029046 APBB2 intron ENSSSCT00000029046 APBB2 intron ENSSSCT00000021654 SNORD113 promoter ENSSSCT00000027797 NSUN7 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009626 . intron ENSSSCT00000009626 . intron ENSSSCT00000009626 . intron ENSSSCT00000009626 . intron ENSSSCT00000009626 . intron ENSSSCT00000009626 . intron . . intergenic ENSSSCT00000009628 SLC30A9 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009639 GABRG1 intron ENSSSCT00000023000 GABRA2 intron ENSSSCT00000023000 GABRA2 intron ENSSSCT00000023000 GABRA2 intron ENSSSCT00000023000 GABRA2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000031430 GABRA4 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009643 CORIN intron ENSSSCT00000009643 CORIN intron ENSSSCT00000009643 CORIN intron ENSSSCT00000009643 CORIN intron ENSSSCT00000009643 CORIN intron ENSSSCT00000009643 CORIN intron ENSSSCT00000009647 . 5'utr ENSSSCT00000009650 TEC intron ENSSSCT00000034638 TEC intron ENSSSCT00000032911 TEC intron ENSSSCT00000009651 SLAIN2 intron

0.102 . 0.174 . 0.189 0.189 0.255 0.125 . 0.15 0.159 . 0.113 -0.12 0.05 -0.005 . . 0.128 0.128 . -0.176 -0.106 0.086 0.085 0.118 0.2 -0.092 0.105 -0.156 0.017 -0.141 -0.065 . . 0.067 0.214 -0.107 0.451 0.077 -0.191 0.004 . . . -0.363 0.095 0.034 0.356 . -0.074 -0.066 -0.131 -0.097 0.13 -0.262 0.078 0.053 -0.161 0.062 0.058 -0.017 . 0.415 -0.135 0.098 . 0.179 0.055 0.226 . 0.092 0.123 . . 0.564 . 0.215 . . . . . 0.169

rs791090893 rs793154833 942117 rs7932 rs793298239 rs792250336 rs792250336 . 336555 rs7908 rs787952444 rs788084415 724990 rs7891 291455 rs7862 176750 rs7894 rs786651508 rs787275632 rs791542617 . . 151716 rs7907 151716 rs7907 rs790423517 . rs790306378 rs792663288 . rs790574690 rs788111804 rs791656724 728622 rs7877 rs788626397 rs791132607 269980 rs7875 666624 rs7928 rs792295059 rs787596028 992400 rs7935 rs792201830 774794 rs7909 rs695568172 rs786693670 rs786491275 rs788479877 . rs792293909 rs786590782 . rs787948698 rs792420495 rs786874686 rs786645821 373158 rs7862 rs792407059 845338 rs7897 rs788459224 . rs788905739 rs791120518 rs790037569 . . . 140557 rs7927 787864 rs7924 rs790913325 rs786790150 rs786450046 247513 rs7901 981030 rs7927 416983 rs7867 rs793401290 rs788869750 392486 rs7919 rs787926822 678038 rs7929 868262 rs7928 107595 rs7912 . rs793042598 rs788764519 rs787891231 rs787738707 rs787738707 rs787738707 813417 rs7898

2 4 2 2 2 2 2 2 2 4 2 2 3 3 2 4 2 4 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 3 2 2 2 3 3 4 2 5 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 4 4 2 2 3 2 2 2 2 2 2 2 4

AAAG.CTTT AAAG.CTTT AATT.AATT AATT.AATT AATT.AATT AAAAT.ATTTT AC.GT ACCT.AGGT AAT.ATT AAAC.GTTT AG.CT AC.GT AAAC.GTTT AAAAC.GTTTT AC.GT AAAC.GTTT AGAT.ATCT AAAC.GTTT AG.CT AG.CT AC.GT AAAAAG.CTTTTT AC.GT AAC.GTT AT.AT AAAT.ATTT AC.GT AGC.GCT AGAT.ATCT AC.GT AC.GT ATC.GAT ACAT.ATGT AAAT.ATTT AG.CT AC.GT ACAG.CTGT AT.AT AAAG.CTTT AC.GT AG.CT AC.GT AAAAAT.ATTTTT AAAC.GTTT AT.AT AAAAC.GTTTT AAAAG.CTTTT AAAG.CTTT AAG.CTT AT.AT AAT.ATT AT.AT AT.AT AT.AT AG.CT AAAC.GTTT AG.CT ACAG.CTGT AG.CT AC.GT AAC.GTT AT.AT AG.CT AC.GT AC.GT AAC.GTT AAAC.GTTT AAAC.GTTT AAAG.CTTT AAAC.GTTT AAAC.GTTT AC.GT AAAC.GTTT AC.GT AG.CT AATG.CATT AAAC.GTTT AAC.GTT AC.GT AAG.CTT AT.AT AG.CT AAAC.GTTT AAG.CTT

8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8

40304801 40377412 40664143 40664143 40664143 40817679 41078009 41142287 41209492 41313461 41478949 41479686 41507953 41571645 41711513 41779688 41997816 42005708 42254432 42283657 42347517 42567825 42606499 42758195 42797523 42821463 42936250 43184403 43359612 43456336 43571669 43600998 43751297 43756893 43861747 44173301 44415305 44583718 44711347 44790654 44810410 45195809 45233188 45245155 45323120 45879863 45879966 46033898 46185199 46326414 46679337 46698160 46714320 47108919 47607888 47696141 47747886 47990166 48036276 48269967 48283207 48324057 48410232 48793442 48802149 48978726 49038798 49199019 49201555 49289902 49296999 49368631 49405200 49491226 49940941 49942920 50415079 50433122 50441924 50448077 50497456 50602985 50776954 50846585

40304821 40377434 40664166 40664166 40664166 40817698 41078021 41142317 41209505 41313477 41478965 41479707 41507979 41571672 41711526 41779703 41997830 42005726 42254442 42283673 42347527 42567849 42606508 42758211 42797546 42821477 42936263 43184419 43359627 43456350 43571683 43601015 43751319 43756913 43861776 44173315 44415319 44583728 44711365 44790673 44810420 45195823 45233206 45245171 45323147 45879892 45879984 46033925 46185218 46326423 46679355 46698172 46714344 47108930 47607912 47696168 47747922 47990184 48036285 48269976 48283223 48324067 48410248 48793461 48802159 48978741 49038813 49199043 49201567 49289925 49297037 49368647 49405225 49491240 49940952 49942949 50415103 50433147 50441933 50448094 50497466 50602999 50776968 50846604

5.25 5.75 6 6 6 4 6.5 7.75 4.66667 4.25 8.5 11 6.75 5.6 7 4 3.75 4.75 5.5 8.5 5.5 4.16667 5 5.66667 12 3.75 7 5.66667 4 7.5 7.5 6 5.75 5.25 15 7.5 3.75 5.5 4.75 10 5.5 7.5 3.16667 4.25 14 6 3.8 7 6.66667 5 6.33333 6.5 12.5 6 12.5 7 18.5 4.75 5 5 5.66667 5.5 8.5 10 5.5 5.33333 4 6.25 3.25 6 9.75 8.5 6.5 7.5 6 7.5 6.25 8.66667 5 6 5.5 7.5 3.75 6.66667

ENSSSCT00000009651 . ENSSSCT00000009661 ENSSSCT00000031947 ENSSSCT00000009658 . ENSSSCT00000009664 . ENSSSCT00000009666 ENSSSCT00000009669 . . . . . . . . ENSSSCT00000009672 . . . . . . . . . . . ENSSSCT00000009679 ENSSSCT00000009679 . . . . . . . . . . . . . . . . . . . . ENSSSCT00000009708 . . ENSSSCT00000024403 ENSSSCT00000024403 . . ENSSSCT00000022356 . . . . . . . . . ENSSSCT00000009714 ENSSSCT00000009714 ENSSSCT00000009715 ENSSSCT00000009715 . ENSSSCT00000009716 ENSSSCT00000009716 ENSSSCT00000009724 ENSSSCT00000009724 ENSSSCT00000009724 ENSSSCT00000009724 ENSSSCT00000009724 ENSSSCT00000009724 . .

SLAIN2 . . . . . CWH43 . DCUN1D4 SGCB . . . . . . . . . . . . . . . . . . . . KIT KIT . . . . . . . . . . . . . . . . . . . . TDO2 . . PDGFC PDGFC . . GRIA2 . . . . . . . . . FAM198B FAM198B TMEM144 TMEM144 . RXFP1 RXFP1 RAPGEF2 RAPGEF2 RAPGEF2 RAPGEF2 RAPGEF2 RAPGEF2 . .

intron intergenic intron intron intron intergenic intron intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron 3'utr intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intron intron intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intergenic intron intron intron intron intron intron intron intron intergenic intergenic

0.22 0.284 0.073 0.073 0.073 . 0.293 . 0.035 . -0.086 0.31 . . 0.119 . 0.397 0.151 . 0.513 0.141 . . 0.112 . 0.38 0.215 0.004 0.124 0.157 0.311 0.284 -0.037 -0.071 -0.077 . . . . . . . -0.003 -0.062 0.094 . . . . -0.274 . . -0.068 . -0.308 0.032 0.044 -0.052 0.064 . 0.064 . . 0.138 -0.149 -0.186 . 0.211 0.191 . 0.07 . 0.268 -0.08 -0.008 0.159 0.211 0.244 -0.021 0.109 -0.145 0.052 0.108 -0.035

rs789645700 rs792034078 653409 rs7862 653409 rs7862 653409 rs7862 rs793779590 . rs793454760 rs786252079 rs792319300 . rs788884059 422525 rs7913 rs786425298 . rs787332826 rs786238981 rs791676588 rs787270967 rs790591198 . rs791931395 rs788590117 rs786339186 rs791913163 . rs789387043 825193 rs7911 rs786297559 . 291962 rs7925 rs788115809 rs790076446 661952 rs7870 . 106291 rs7885 493438 rs7897 rs786674947 rs787124809 rs791837194 . 900950 rs7921 . 847394 rs7898 rs793874905 rs791407686 rs789636985 595770 rs7923 . . rs792287461 578636 rs7888 . 168555 rs7891 rs791882825 rs788914386 rs793636139 rs786950441 092168 rs7914 . 179032 rs7931 418410 rs7921 983417 rs7912 rs791550964 rs786395102 rs786282356 rs786835263 rs790737468 rs790049598 rs791258912 rs793214506 719365 rs7870 480486 rs7874 617473 rs7932 . 384637 rs7910 . rs789906347 rs791499977 rs787601230 . 928640 rs7884 rs791148525 rs692361014

2 2 2 2 2 2 3 2 3 2 2 3 2 2 4 2 2 2 3 2 3 2 2 3 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 4 3 3 2 2 2 2 2 2 2 2 4 2 4 2 3 2 3 2 2 2 2 2 2 2 5 2 2 2 2 2 2 2 2 2 2

AAAG.CTTT AT.AT AT.AT AT.AT AC.GT ACAT.ATGT AAAAAT.ATTTTT AG.CT AAAC.GTTT AAAC.GTTT AAAT.ATTT AT.AT AT.AT AT.AT AT.AT AT.AT AT.AT AAG.CTT AG.CT AAAC.GTTT AC.GT AAAG.CTTT AAT.ATT AC.GT AAT.ATT AAAC.GTTT AAAAT.ATTTT AAAC.GTTT AAAC.GTTT AG.CT AAAAC.GTTTT AAAT.ATTT AAT.ATT AGG.CCT AG.CT AAAAC.GTTTT AC.GT AG.CT AT.AT AC.GT AATAT.ATATT AC.GT AG.CT AC.GT AC.GT AAAAG.CTTTT AC.GT AAG.CTT AT.AT AC.GT AC.GT AAAC.GTTT AAT.ATT AT.AT AT.AT AC.GT AC.GT AAAAC.GTTTT AAC.GTT AT.AT AT.AT AAAT.ATTT AAAC.GTTT AC.GT AAG.CTT AG.CT AC.GT AAAT.ATTT AT.AT AAAAG.CTTTT AT.AT AT.AT AAAC.GTTT AAAC.GTTT AAGAG.CTCTT AAAC.GTTT AT.AT AAAT.ATTT AATAT.ATATT AAAT.ATTT AAAC.GTTT AAAC.GTTT AC.GT AC.GT

8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8

51045015 51476416 51582470 51754664 52270189 52663055 52911237 53036524 53471457 53592692 53854051 53905830 54107095 54196180 54239430 54253165 54445307 54494987 54751514 55129746 55443037 55487644 55707762 55806884 55938873 57478310 58250231 58364598 58364598 58384838 59417862 59554623 59557202 59827401 60008113 60040514 60041947 60280893 60447576 61028293 61036649 61078556 61154656 61180483 61224449 61267183 61804676 62910737 62915264 63452870 63569659 63945963 64732492 64790943 65113003 65575336 66068232 66128879 66689283 66695811 66894734 67082956 67308353 67570966 68164132 68635294 68691734 68726332 68729987 68731269 68751812 68797185 68878094 68879923 68906245 69050660 69110618 69171697 69176466 69570670 69608389 69826818 70011717 70042508

51045033 51476426 51582479 51754674 52270199 52663091 52911259 53036535 53471488 53592711 53854069 53905843 54107118 54196189 54239450 54253174 54445320 54495001 54751530 55129772 55443049 55487662 55707784 55806894 55938884 57478324 58250248 58364618 58364618 58384848 59417882 59554643 59557218 59827417 60008123 60040545 60041957 60280903 60447586 61028314 61036668 61078567 61154678 61180504 61224459 61267217 61804688 62910752 62915278 63452882 63569675 63945993 64732505 64790953 65113014 65575345 66068250 66128899 66689294 66695822 66894744 67082976 67308366 67570979 68164147 68635314 68691744 68726346 68729998 68731286 68751826 68797198 68878124 68879938 68906270 69050683 69110628 69171715 69176480 69570685 69608418 69826840 70011728 70042523

4.75 5.5 5 5.5 5.5 9.25 3.83333 6 8 5 4.75 7 12 5 10.5 5 7 5 8.5 6.75 6.5 4.75 7.66667 5.5 4 3.75 3.6 5.25 5.25 5.5 4.2 5.25 5.66667 5.66667 5.5 6.4 5.5 5.5 5.5 11 4 6 11.5 11 5.5 7 6.5 5.33333 7.5 6.5 8.5 7.75 4.66667 5.5 6 5 9.5 4.2 4 6 5.5 5.25 3.5 7 5.33333 10.5 5.5 3.75 6 3.6 7.5 7 7.75 4 5.2 6 5.5 4.75 3 4 7.5 5.75 6 8

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000031578 . intron ENSSSCT00000031578 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009730 NAF1 intron . . intergenic ENSSSCT00000009733 TMA16 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000031478 CEP135 intron ENSSSCT00000024124 EXOC1 intron ENSSSCT00000031053 EXOC1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009766 EPHA5 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009772 UBA6 intron ENSSSCT00000009774TMPRSS11D intron . . intergenic

. -0.255 . . . -0.196 . -0.007 -0.16 -0.059 -0.008 -0.067 -0.021 . . . . . -0.017 . 0.331 0.057 . -0.025 . . 0.213 . . . . -0.146 0.046 . -0.155 -0.062 . 0.061 0.046 -0.024 -0.073 . -0.03 -0.053 0.076 . -0.021 . -0.062 0.023 . . . . -0.008 0.042 . . 0.105 -0.251 -0.08 0.032 -0.058 0.009 0.352 -0.2 . . . . -0.042 0.167 0.071 0.164 0.054 0.243 0.339 0.041 0.125 . -0.142 . 0.123 0.073

816166 rs7934 . rs786400394 rs789838316 . rs787339990 rs791299875 rs791123957 765810 rs7900 rs788981500 rs789656641 772649 rs7929 . rs793236790 . rs793389893 913267 rs7878 rs712339377 . 597464 rs7887 rs791863805 594924 rs7863 749853 rs7888 rs789365908 rs790993968 rs791713968 . rs789916947 rs789916947 . 395923 rs7895 rs790788215 rs790304180 rs793360760 rs788836008 841506 rs7893 rs790964506 rs786739170 rs786908465 rs792438350 633785 rs7910 . 176603 rs7915 831109 rs7887 . 210466 rs7865 rs789556391 649029 rs7869 325458 rs7877 rs693017382 rs791043259 rs789917065 rs792571248 . rs792448791 . rs789776985 rs792031846 084391 rs7885 rs793584436 . rs793809298 803250 rs7925 . 356026 rs7885 . 229607 rs7885 967193 rs7897 rs787458737 rs787254727 rs793659346 064349 rs7898 260381 rs7890 rs789471982 rs787470268 884085 rs7938 rs791033739 658726 rs7881 rs787802345 rs786259550 117922 rs7897 . 336963 rs7907 .

3 2 2 2 3 2 2 2 2 2 2 3 2 2 3 2 2 3 3 2 3 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 4 2 3 4 2 2 2 2 4 2 2 3 2 2 2 2 4 2 3 2 2 3 2 2 2 2 2 2 2 2 2 2 2 3 2 2 4

AT.AT AATG.CATT AAAC.GTTT AAAT.ATTT AC.GT AAAC.GTTT AC.GT AT.AT AAAC.GTTT AG.CT ACC.GGT AGG.CCT AAC.GTT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AG.CT AT.AT AAAC.GTTT AT.AT AAC.GTT AAAC.GTTT AAAC.GTTT AC.GT AC.GT AG.CT AATG.CATT AATG.CATT AT.AT AC.GT AT.AT AAAT.ATTT AC.GT AAC.GTT AT.AT AAG.CTT AAAC.GTTT AAC.GTT AC.GT AAAT.ATTT AAAC.GTTT AGC.GCT AAC.GTT AAAC.GTTT AAAAC.GTTTT AAAAC.GTTTT AC.GT AAAC.GTTT AAAC.GTTT AT.AT AT.AT AAT.ATT AGAT.ATCT AATG.CATT AC.GT AG.CT AG.CT AGC.GCT AGC.GCT AAAT.ATTT AAAC.GTTT AAAT.ATTT AAAAC.GTTTT AAAAG.CTTTT AC.GT ACAT.ATGT AC.GT AT.AT AAC.GTT AC.GT AC.GT AC.GT AAAC.GTTT AC.GT AAAC.GTTT AAAAC.GTTTT AAAC.GTTT AAAAT.ATTTT AC.GT AT.AT AG.CT AG.CT AAAAC.GTTTT AG.CT

8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8

70082277 70217402 70333636 71010004 71066821 71435419 71465489 71479301 71626546 71675210 71756942 71932406 72175901 72198053 72547496 72615482 73349289 73401800 73645333 73665856 73856440 74085318 74085318 74287530 74345732 74669315 75003925 75067531 75117399 75176789 75402189 75633243 75685581 75807173 75999719 76038457 76271101 76283154 76552878 76622407 76760036 76760479 76799178 76841025 76886631 76940293 76976357 76978499 77208423 77281229 77475392 77575350 77936537 77945365 78013339 78177671 78177671 78192532 78192532 78417267 78675449 78744053 78786674 78817776 78823662 79250477 79294724 79500546 79570134 79869007 80272492 80595649 80937423 80993290 81072583 81429119 81582691 81730123 81864449 81885890 81968730 81968730 82013506 82631867

70082287 70217426 70333650 71010030 71066834 71435452 71465507 71479312 71626576 71675226 71756960 71932421 72175912 72198087 72547516 72615501 73349301 73401810 73645350 73665866 73856469 74085332 74085332 74287549 74345744 74669325 75003953 75067552 75117414 75176818 75402206 75633264 75685595 75807186 75999730 76038469 76271115 76283175 76552889 76622424 76760055 76760497 76799189 76841042 76886649 76940325 76976367 76978522 77208460 77281239 77475403 77575362 77936553 77945379 78013355 78177680 78177680 78192546 78192546 78417288 78675471 78744088 78786703 78817793 78823672 79250492 79294744 79500567 79570150 79869019 80272507 80595666 80937441 80993300 81072601 81429138 81582708 81730149 81864461 81885903 81968740 81968740 82013524 82631882

5.5 6.25 3.75 6.75 7 8.5 9.5 6 7.75 8.5 6.33333 5.33333 4 7 5.25 5 6.5 5.5 4.5 5.5 10 3.75 3.75 10 6.5 5.5 7.25 5.5 8 15 9 5.5 7.5 4.66667 6 4.33333 3.75 7.33333 6 4.5 5 6.33333 4 4.5 3.8 6.6 5.5 6 9.5 5.5 6 4.33333 4.25 3.75 8.5 5 5 5 5 5.5 5.75 9 6 3.6 5.5 4 10.5 11 5.66667 6.5 8 9 4.75 5.5 4.75 4 4.5 5.4 6.5 7 5.5 5.5 3.8 8

ENSSSCT00000009775TMPRSS11A intron ENSSSCT00000009778TMPRSS11F intron . . intergenic . . intergenic ENSSSCT00000022622 SULT1B1 intron ENSSSCT00000028087 RUFY3 intron ENSSSCT00000028087 RUFY3 intron . . intergenic ENSSSCT00000009795 DCK intron . . intergenic . . intergenic ENSSSCT00000009797 SLC4A4 intron . . intergenic . . intergenic ENSSSCT00000009798 NPFFR2 intron . . intergenic ENSSSCT00000009801 COX18 intron ENSSSCT00000028188 ANKRD17 intron . . intergenic . . intergenic ENSSSCT00000026155 . intron ENSSSCT00000034805 IL8 exon ENSSSCT00000009807 IL8 intron ENSSSCT00000009813 CXCL2 intron ENSSSCT00000009815 MTHFD2L intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009827 PPEF2 intron ENSSSCT00000023437 CXCL9 promoter ENSSSCT00000009834 . intron ENSSSCT00000009835 SCARB2 intron ENSSSCT00000009840 CCDC158 intron ENSSSCT00000009840 CCDC158 intron ENSSSCT00000009841 SHROOM3 intron ENSSSCT00000009841 SHROOM3 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000009843 11-Sep intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009848 FRAS1 intron ENSSSCT00000009848 FRAS1 intron ENSSSCT00000009848 FRAS1 intron ENSSSCT00000009848 FRAS1 intron ENSSSCT00000033980 FRAS1 intron ENSSSCT00000009848 FRAS1 intron ENSSSCT00000033980 FRAS1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009857 DCHS2 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000026657 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009874 . intron ENSSSCT00000009874 . intron ENSSSCT00000025424 . intron ENSSSCT00000026948 . intron . . intergenic . . intergenic

-0.073 -0.106 . -0.202 -0.033 0.11 0.209 0.472 . 0.005 0.006 -0.094 0.303 -0.011 -0.05 0.001 . 0.089 . 0.232 . 0.196 0.196 . 0.069 . 0.07 -0.058 0.173 0.112 0.141 . -0.141 0.252 0.277 0.148 0.178 0.433 0.235 -0.158 0.108 0.141 0.208 0.034 -0.13 0.207 . 0.355 0.11 . . 0.237 0.102 0.155 0.274 0.158 0.158 -0.104 -0.104 -0.149 0.266 . -0.085 0.038 . . . 0.107 0.215 0.086 0.266 -0.235 . 0.199 0.25 -0.299 -0.038 0.18 -0.238 . 0.004 0.004 0.165 .

rs793760924 570820 rs7916 rs789811992 rs792021702 . 003582 rs7868 rs790160040 970210 rs7879 rs697598100 rs709910177 . 876467 rs7928 rs791723288 783658 rs7915 rs792840995 rs790118981 . 417081 rs7916 rs789950904 rs786622707 rs789418853 rs787169444 rs787169444 rs788330415 846913 rs7869 . rs787853987 rs787880101 rs790883650 388673 rs7869 841467 rs7931 rs703889887 273105 rs7937 274640 rs7898 rs792507106 rs791490063 354887 rs7882 rs789528174 rs786629207 rs790495872 . rs787744147 344578 rs7898 351911 rs7878 rs789016495 376518 rs7872 . 509497 rs7867 rs792264292 . rs792092433 . rs792177883 rs793504321 rs793672627 . . rs793025269 rs793025269 rs791711702 rs789644404 091749 rs7880 rs790191916 rs787947846 167672 rs7928 rs792215963 . . rs791836760 350484 rs7929 rs787826674 rs792390679 rs789524571 rs789829086 . rs792236132 rs788773572 rs788081839 rs786425197 527299 rs7869 197022 rs7862 197022 rs7862 rs790437713 .

2 3 2 2 4 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 4 2 2 2 4 2 2 3 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 4 3 2 3 2 2 2 2 3 3 2 4

AG.CT AC.GT AC.GT AAC.GTT AAAAC.GTTTT AC.GT AT.AT AAG.CTT AAAT.ATTT AAAT.ATTT AT.AT AC.GT AAAC.GTTT AAC.GTT AAC.GTT AAAG.CTTT AAAAG.CTTTT AAC.GTT ATC.GAT AC.GT AAG.CTT AAAAT.ATTTT AAGG.CCTT AG.CT AAAC.GTTT AAAG.CTTT AG.CT AC.GT AC.GT ACACT.AGTGT AAT.ATT ATC.GAT AT.AT AT.AT AAAAC.GTTTT AT.AT AAAAT.ATTTT AG.CT AC.GT AAC.GTT AAC.GTT AAC.GTT AAC.GTT ACAT.ATGT ACAT.ATGT ACAT.ATGT ACAT.ATGT AC.GT AAAAAC.GTTTTT AT.AT AT.AT AC.GT AAAAG.CTTTT ACAT.ATGT AAAC.GTTT AAAAAG.CTTTTT AT.AT AT.AT AAAG.CTTT AC.GT AAT.ATT AT.AT AAAC.GTTT AG.CT AAAAAC.GTTTTT AT.AT AAAC.GTTT AC.GT AAAG.CTTT AAAAG.CTTTT AG.CT AAAC.GTTT AG.CT AAAT.ATTT AC.GT AAAT.ATTT AAAC.GTTT AGG.CCT AGAGGG.CCCTC AC.GT AAT.ATT AAAC.GTTT AG.CT AAAAAC.GTTTTT

8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8

83276796 83310175 83716839 83779582 83842194 83934926 84187809 84277153 84305658 84527843 84722179 84918852 84945004 85269813 85414360 85711930 85865503 85950160 86234778 86390457 86510398 86541751 86846923 87116246 87291578 87522887 87720708 87939074 88065599 88165874 88184186 88322671 88546363 88621518 88739397 88996470 89125837 89284309 89296098 89415374 89415374 89415374 89415374 89442988 89442988 89442988 89442988 89698438 89809327 89828034 89970000 90061360 90163843 90200161 90475084 90568094 91041190 91047381 91159653 91406975 91429833 91673450 91820233 91929226 91942921 92117882 92349182 92360455 92412029 92413018 92443487 92471131 92776289 92794722 92844092 93171338 93273732 93637680 93655286 93683940 93700622 93789494 93832230 93915894

83276818 83310189 83716853 83779594 83842213 83934936 84187819 84277167 84305676 84527865 84722193 84918864 84945018 85269839 85414391 85711954 85865520 85950173 86234805 86390469 86510411 86541765 86846941 87116256 87291599 87522928 87720718 87939086 88065612 88165904 88184200 88322691 88546375 88621534 88739417 88996489 89125854 89284319 89296120 89415390 89415390 89415390 89415390 89443003 89443003 89443003 89443003 89698455 89809350 89828043 89970011 90061372 90163870 90200184 90475104 90568121 91041200 91047390 91159676 91406985 91429859 91673461 91820254 91929239 91942946 92117898 92349209 92360469 92412060 92413036 92443503 92471154 92776313 92794742 92844103 93171359 93273743 93637711 93655304 93683958 93700641 93789509 93832246 93915921

11.5 7.5 7.5 4.33333 4 5.5 5.5 5 4.75 5.75 7.5 6.5 3.75 9 10.6667 6.25 3.6 4.66667 9.33333 6.5 4.66667 3 4.75 5.5 5.5 10.5 5.5 6.5 7 6.2 5 7 6.5 8.5 4.2 10 3.6 5.5 11.5 5.66667 5.66667 5.66667 5.66667 4 4 4 4 9 4 5 6 6.5 5.6 6 5.25 4.66667 5.5 5 6 5.5 9 6 5.5 7 4.33333 8.5 7 7.5 8 3.8 8.5 6 12.5 5.25 6 5.5 3 10.6667 3.16667 9.5 6.66667 4 8.5 4.66667

ENSSSCT00000009880 . intron ENSSSCT00000009880 . intron ENSSSCT00000009882 DCLK2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009887 . intron . . intergenic ENSSSCT00000009888 ARHGAP10 intron ENSSSCT00000024567 TMEM184C intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009895 SLC10A7 intron ENSSSCT00000009895 SLC10A7 intron ENSSSCT00000009896 LSM6 intron ENSSSCT00000009897 ZNF827 intron ENSSSCT00000009897 ZNF827 intron ENSSSCT00000009899 MMAA intron . . intergenic . . intergenic ENSSSCT00000009902 OTUD4 intron ENSSSCT00000009903 ABCE1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000035764 GAB1 intron ENSSSCT00000032897 GAB1 intron ENSSSCT00000009909 GAB1 intron ENSSSCT00000034785 GAB1 intron ENSSSCT00000035764 GAB1 intron ENSSSCT00000032897 GAB1 intron ENSSSCT00000009909 GAB1 intron ENSSSCT00000034785 GAB1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009917 RNF150 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000025519 CLGN intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000009924 MAML3 intron ENSSSCT00000009924 MAML3 intron ENSSSCT00000009924 MAML3 intron ENSSSCT00000023019 SETD7 promoter ENSSSCT00000009925 NAA15 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

0.592 0.103 -0.035 0.131 0.094 . 0.056 0.208 0.129 0.068 . -0.021 . 0.199 0.153 0.045 -0.086 -0.246 0.348 . -0.119 0.048 0.111 . . 0.138 0.096 0.236 -0.126 -0.095 0.031 0.148 0.019 0.196 . 0.328 0.134 0.059 -0.048 -0.011 -0.011 -0.011 -0.011 -0.058 -0.058 -0.058 -0.058 . . . . . -0.319 0.086 0.02 -0.027 -0.21 0.162 0.223 . . 0.082 0.005 0.909 4.676 . . -0.108 0.13 -0.118 1.363 0.05 0.234 0.014 -0.016 -0.012 0.302 -0.015 0.312 0.125 -0.114 0.89 0.32 .

070724 rs7912 rs793851378 rs787433440 926075 rs7931 277513 rs7931 . rs793253003 931580 rs7885 827282 rs7920 rs793842754 rs793070837 . rs788246631 rs791800333 789549 rs7895 . rs788365714 rs791978842 rs788579003 rs789663181 325773 rs7876 391942 rs7887 rs793300148 481012 rs7896 rs691279881 952842 rs7935 rs792747840 rs711022675 rs789759401 rs786278734 rs791654811 . . rs790966375 rs793582133 927356 rs7869 rs792161080 rs706713104 rs698405364 rs788670556 rs788670556 rs788670556 rs788670556 rs792609848 rs792609848 rs792609848 rs792609848 . rs786532742 rs791236800 rs791283052 . . rs701251270 rs789986005 rs788664084 . . 582107 rs7935 rs704900651 . rs793444097 133014 rs7881 rs788170884 394968 rs7932 145227 rs7912 rs692904740 rs792902566 610659 rs7913 303559 rs7921 . rs793575196 024362 rs7894 rs789976924 rs790696088 rs793676997 . rs789146764 502878 rs7891 244728 rs7921 rs793011633 rs788256051 rs792370359 020826 rs7882

2 2 2 2 2 2 2 2 2 2 2 5 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 4 2 2 3 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 3 2 2 2 2 3 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 4 2 2 2 4 2 2

AAAAT.ATTTT AC.GT AT.AT AAAAT.ATTTT AC.GT AT.AT AC.GT AAAT.ATTT AT.AT AAAT.ATTT AC.GT AC.GT AC.GT AT.AT AAC.GTT AAT.ATT AAT.ATT AT.AT AAT.ATT ACAT.ATGT AAAAC.GTTTT AT.AT AAAC.GTTT AC.GT AC.GT AAG.CTT AAT.ATT AAAATT.AATTTT AT.AT AAC.GTT AC.GT AAAC.GTTT AT.AT AAAC.GTTT AT.AT AG.CT AC.GT AAG.CTT AG.CT AAG.CTT AAT.ATT AAC.GTT AAATT.AATTT AAAG.CTTT AT.AT AT.AT AG.CT AT.AT AT.AT AG.CT AT.AT ACAT.ATGT AAAT.ATTT AAC.GTT AG.CT AC.GT AT.AT AC.GT AAAT.ATTT AT.AT AT.AT AT.AT AC.GT AAT.ATT AT.AT AAAC.GTTT AAAC.GTTT AAT.ATT AC.GT AAC.GTT AAC.GTT AAAC.GTTT AT.AT AG.CT AC.GT AAC.GTT AAC.GTT ACACAG.CTGTG AAAC.GTTT AAAAC.GTTTT AAT.ATT AC.GT AAAC.GTTT AT.AT

8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8

93933067 94000650 94721307 94742901 94977359 95017884 95067400 95614715 95621757 95952526 96173489 96650931 96744815 96756116 96864549 97207244 97450882 97593048 97594584 97960232 98473310 98667735 99048097 99729898 99817925 99846058 99918683 100234007 100275194 100401074 100444141 100645317 100836210 100837552 100856552 101080528 101333963 101415998 101495129 101700130 101701559 101746947 101834134 102181908 102185659 102285986 102347106 102521872 102970805 103259266 103326644 103452423 103551882 103588600 104156558 104174261 104487782 104614747 104830684 104873226 104892053 104982112 104995039 105201215 105208019 105296521 105302566 105382277 105801999 106293540 106575308 106678236 106853438 107110857 107256051 107263218 107439524 107541120 107545062 107760093 107951135 108092922 108143946 108262947

93933093 94000673 94721322 94742934 94977369 95017894 95067413 95614727 95621768 95952544 96173508 96650956 96744827 96756127 96864575 97207266 97450893 97593059 97594596 97960256 98473330 98667744 99048122 99729910 99817949 99846075 99918695 100234034 100275204 100401086 100444167 100645344 100836220 100837569 100856579 101080540 101333978 101416010 101495141 101700145 101701573 101746958 101834148 102181932 102185674 102285995 102347122 102521881 102970821 103259282 103326657 103452442 103551908 103588613 104156570 104174273 104487812 104614760 104830700 104873236 104892067 104982122 104995059 105201228 105208030 105296535 105302594 105382302 105802016 106293555 106575320 106678262 106853457 107110869 107256071 107263232 107439537 107541143 107545084 107760111 107951156 108092945 108143968 108262956

5.4 . 12 . 8 . 6.8 . 5.5 . 5.5 . 7 . 3.25 . 6 . 4.75 . 10 . 13 . 6.5 . 6 . 9 . 7.66667 . 4 . 6 . 4.33333 . 6.25 . 4.2 . 5 . 6.5 . 6.5 . 12.5 . 6 . 4.33333 . 4.66667 . 5.5 . 4.33333 . 13.5 . 7 . 5.5 . 4.5 . 14 . 6.5 . 8 . 4.33333 . 6.5 . 5.33333 . 5 . 4 . 3 . 6.25 . 8 . 5 . 8.5 . 5 . 8.5 . 8.5 . 7 . 5 . 6.75 . 4.66667 . 6.5 . 6.5 . 15.5 . 7 . 4.25 . 5.5 . 7.5 . 5.5 . 10.5 . 4.66667 . 6 . 3.75 . 7.25 . 8.66667 . 9 . 5.33333 . 4.33333 . 6.75 . 10 . 6.5 . 10.5 . 5 . 4.66667 . 4 . 5.75 . 3.8 . 7.33333 . 12 ENSSSCT00000009949 5.75 ENSSSCT00000009949 5 .

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . SPRY1 SPRY1 .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic

0.031 0.199 . 0.072 -0.1 0.068 -0.069 -0.37 . -0.218 0.026 -0.14 . . 0.11 . -0.077 -0.039 0.034 -0.136 0.136 -0.073 -0.133 -0.11 . 0.356 -0.101 . 0.443 0.057 0.094 . 0.095 . -0.158 0.347 -0.051 -0.271 0.143 . -0.044 0.09 -0.089 0.631 -0.024 . 0.86 . 0.31 -0.072 . 0.08 . 0.267 0.117 0.267 0.117 0.173 . 0.031 0.075 0.115 -0.088 0.06 0.173 0.164 0.138 0.09 -0.097 0.145 . 0.064 0.118 -0.051 . . 0.834 0.705 0.252 0.026 0.287 . 0.061 0.312

rs791942175 006451 rs7917 rs788303461 571436 rs7895 . . . rs792132135 rs789346333 rs793514596 . rs702409172 . rs793734143 676630 rs7880 . 922870 rs7910 rs793203853 512499 rs7871 rs793563877 762525 rs7928 rs790893134 rs789978003 rs792405928 . 951730 rs6964 267361 rs7894 . . . 949730 rs7866 rs791913849 148702 rs7932 rs787056481 . rs789979081 168895 rs7881 524760 rs7938 642192 rs7873 rs786424775 847959 rs7911 rs791926486 rs791137508 . rs710100018 rs787640464 969401 rs7863 rs790207742 rs790056631 rs786630660 547645 rs7926 rs787222517 . rs786235878 rs791212598 459430 rs7864 rs791965747 838966 rs7870 rs789251433 rs787418768 148484 rs7890 rs792059120 rs792114878 rs787373892 rs786486203 rs793715082 954657 rs7863 rs789047280 694229 rs7912 rs788424993 376083 rs7928 rs793088360 rs789312532 306728 rs7938 . . 272483 rs7932 rs702978370 rs793206206 rs789072172 . . rs791728360 rs788404786

2 2 2 2 4 3 3 2 2 2 4 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 4 2 2 4 3 2 2 2 4 4 2 3 2 2 2 2 4 2 3 2 4 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2

AAAG.CTTT AG.CT AT.AT AAAT.ATTT AG.CT AAAC.GTTT AT.AT AAG.CTT AC.GT AGAGAT.ATCTCT AAAC.GTTT AT.AT AT.AT AAAC.GTTT AC.GT AAT.ATT AG.CT AC.GT AAAT.ATTT AAAG.CTTT AC.GT AG.CT AAAG.CTTT AAAT.ATTT AAAAAG.CTTTTT AAAAG.CTTTT AAAAG.CTTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AT.AT ACACT.AGTGT AAAC.GTTT AT.AT AC.GT AAAAT.ATTTT AGC.GCT AAC.GTT AAAT.ATTT AC.GT AAGG.CCTT AC.GT AT.AT AC.GT AC.GT AC.GT AC.GT AG.CT AG.CT AG.CT AG.CT AC.GT AG.CT AG.CT AATG.CATT AAAAC.GTTTT AC.GT AAAC.GTTT AAAAC.GTTTT AAG.CTT AAAAT.ATTTT AAAG.CTTT AAC.GTT AAAT.ATTT AG.CT AAAT.ATTT AAT.ATT AC.GT AT.AT AAAT.ATTT AAAC.GTTT AG.CT AAAAAC.GTTTTT ATC.GAT AAAC.GTTT AT.AT AAAG.CTTT AAC.GTT AC.GT AAT.ATT AAAT.ATTT AAAG.CTTT AAAC.GTTT ACT.AGT

8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8

108381713 108388784 108485432 108495015 108609204 108995826 108999661 109681454 110097270 110513523 110558082 110765689 110765689 111071878 111106857 111195550 111288955 111303333 111378902 111403123 111495352 111591447 111636268 111994856 112041190 112122113 112122113 112135087 112603697 112809590 112820185 112900431 112903285 112996784 113257079 113270875 113289327 113318763 113606573 113688705 113699388 114045852 114292780 114553226 114973363 115438765 115442798 115597542 115645949 115845728 115880801 115972875 116233051 116368299 116830221 116948960 116956673 116976907 117095484 117167096 117451972 117541785 117778506 117911169 117969106 118281050 118376886 118414878 118517659 118709493 118846705 118914274 118937719 119088909 119274291 119277574 119376537 119497860 119715124 119753001 119841495 119842718 119939656 119981230

108381753 108388798 108485444 108495027 108609214 108995840 108999678 109681466 110097284 110513541 110558104 110765698 110765698 111071904 111106868 111195563 111288967 111303345 111378919 111403141 111495363 111591456 111636291 111994871 112041211 112122129 112122129 112135100 112603719 112809617 112820199 112900445 112903310 112996794 113257094 113270892 113289342 113318776 113606597 113688720 113699407 114045862 114292789 114553237 114973377 115438776 115442824 115597552 115645959 115845748 115880815 115972921 116233064 116368312 116830234 116948979 116956688 116976924 117095514 117167107 117451994 117541803 117778517 117911196 117969120 118281071 118376906 118414894 118517684 118709510 118846723 118914289 118937758 119088933 119274322 119277608 119376561 119497873 119715145 119753017 119841526 119842735 119939667 119981241

10.25 7.5 6.5 3.25 5.5 3.75 9 4.33333 7.5 3.16667 5.75 5 5 6.75 6 4.66667 6.5 6.5 4.5 4.75 6 5 6 4 3.66667 3.4 3.4 3.5 5.75 7 7.5 3 6.5 5.5 8 3.6 5.33333 4.66667 6.25 8 5 5.5 5 6 7.5 6 13.5 5.5 5.5 10.5 7.5 23.5 7 7 3.5 4 8 4.5 6.2 4 4.6 4.75 4 7 7.5 5.5 7 8.5 13 4.5 4.75 8 6.66667 8.33333 8 17.5 6.25 4.66667 11 5.66667 8 4.5 3 4

ENSSSCT00000009950 ENSSSCT00000009950 ENSSSCT00000009951 ENSSSCT00000009952 . ENSSSCT00000009956 ENSSSCT00000009956 . . ENSSSCT00000030696 . ENSSSCT00000009967 ENSSSCT00000021244 . . . . . . . ENSSSCT00000009971 . . ENSSSCT00000009973 ENSSSCT00000009973 ENSSSCT00000035856 ENSSSCT00000030658 . ENSSSCT00000009979 . . ENSSSCT00000009981 ENSSSCT00000009981 ENSSSCT00000009982 . . . . . . . . . . . . . . . . . ENSSSCT00000029398 ENSSSCT00000024625 . . . ENSSSCT00000009990 ENSSSCT00000009990 ENSSSCT00000009990 ENSSSCT00000009990 ENSSSCT00000009992 ENSSSCT00000009992 . . . . ENSSSCT00000009996 . . . . . . . . . . . . . . . . ENSSSCT00000036057

SPATA5 SPATA5 NUDT6 FGF2 . KIAA1109 KIAA1109 . . . . PRDM5 U6 . . . . . . . MAD2L1 . . PDE5A PDE5A FABP2 FABP2 . . . . PRSS12 PRSS12 NDST3 . . . . . . . . . . . . . . . . . UGT8 . . . . CAMK2D CAMK2D CAMK2D CAMK2D ANK2 ANK2 . . . . AP1AR . . . . . . . . . . . . . . . . ENPEP

intron intron intron intron intergenic intron intron intergenic intergenic intron intergenic intron promoter intergenic intergenic intergenic intergenic intergenic intergenic intergenic promoter intergenic intergenic intron intron intron intron intergenic intron intergenic intergenic intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic 3'utr intron intergenic intergenic intergenic intron intron intron intron intron intron intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron

0.232 . 0.167 0.157 0.972 . . . 0.121 -0.002 0.14 -0.002 -0.002 0.084 . 0.128 -0.146 -0.098 . 0.166 0.018 . 0.144 . 0.095 0.128 0.128 . -0.041 . 0.047 0.108 0.087 . 0.042 0.38 0.163 -0.019 . -0.015 . . -0.158 -0.077 . . . 0.033 -0.225 -0.037 . 1.228 -0.172 0.14 0.048 0.145 0.854 0.134 0.022 . 0.1 0.095 . . 0.135 0.015 0.268 . 0.328 0.019 . 0.07 -0.065 . 0.049 . 0.585 1.4 0.444 0.046 0.113 0.076 -0.247 0.154

210723 rs7903 214349 rs7880 . . . rs792396051 . rs788384789 . rs792516854 rs786901201 578097 rs7929 578097 rs7929 111202 rs7902 508491 rs7884 rs786430177 627598 rs7881 rs790480222 015065 rs7885 169556 rs7907 . rs690841189 089676 rs7863 . rs788113733 894632 rs7876 894632 rs7876 rs790237937 rs789549504 rs791407909 . rs786771795 673533 rs7880 . rs791835984 rs787778535 rs787003031 rs786861597 rs788957871 873231 rs7925 . rs792796016 rs786224148 rs786765022 rs793548375 . rs788483292 rs790638724 . 483552 rs7874 343722 rs7920 689545 rs7882 . . . rs787665149 855099 rs7891 rs789776342 rs788878118 589042 rs7923 rs791707787 480799 rs7928 rs791705206 . 019882 rs7923 438271 rs7932 940800 rs7862 . rs701802493 . 311913 rs7928 940658 rs7071 rs792488552 rs793541332 863414 rs7918 rs786908678 151872 rs7919 451216 rs7887 878112 rs7919 rs793214643 567433 rs7922 rs792461767 rs788918506 308348 rs7935

3 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 3 2 2 2 2 3 2 4 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 3 4 2 2 2 2 2 3 3 2 2 2 2 3 2 2 2 2 2

ACT.AGT AAAAG.CTTTT AGGG.CCCT ACATAT.ATATGT AT.AT AAAAC.GTTTT AAAG.CTTT AT.AT AAAAT.ATTTT AGG.CCT AC.GT AAAC.GTTT AAC.GTT AAAAC.GTTTT AAAC.GTTT AC.GT AAAAC.GTTTT AAC.GTT AC.GT AT.AT ACAT.ATGT AC.GT AG.CT AAT.ATT AAAGG.CCTTT AT.AT AG.CT AC.GT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AAAAT.ATTTT AAAC.GTTT AT.AT AAAC.GTTT AG.CT AAAT.ATTT ATC.GAT AAAAT.ATTTT AATG.CATT AAAC.GTTT AG.CT AG.CT AAAC.GTTT AC.GT AACCC.GGGTT AAAC.GTTT AAC.GTT AAAT.ATTT AG.CT AT.AT AAAT.ATTT AC.GT AC.GT AT.AT AAT.ATT AAAT.ATTT AAC.GTT AC.GT AC.GT AAAC.GTTT AAAC.GTTT AAC.GTT AG.CT AC.GT AAAG.CTTT AC.GT AG.CT AC.GT AAAC.GTTT AAAAG.CTTTT AC.GT AG.CT AAAAT.ATTTT AG.CT AAAAAC.GTTTTT AAAAC.GTTTT AC.GT AG.CT AAAAC.GTTTT AT.AT AG.CT AT.AT AAAC.GTTT

8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8

119981230 119992546 120160210 120174113 120202080 120227275 120483186 120607456 121247229 121335063 121411454 121434172 121637989 121782039 121957122 121988548 122207416 122312364 122318003 122552445 122560314 122570514 122665874 122872638 122876328 122950347 123029424 123219759 123263287 123291652 123343616 123347577 123475093 123528400 123551452 124052203 124070011 124120722 124124156 124217764 124345399 124666422 124730194 124837581 124903322 125134892 125280352 125503668 125846327 126121715 126147658 126212862 126246707 126310070 126348520 126570966 126681476 126705162 126715239 126718451 126731489 126734829 127083514 127366041 127810579 127815781 127838830 127843084 127897823 128259871 128275866 128313523 128524306 128598311 128607977 128638575 128842147 128982957 129054173 129138121 129213263 129223724 129300405 129501186

119981241 119992562 120160221 120174131 120202090 120227303 120483200 120607466 121247245 121335080 121411466 121434200 121638011 121782057 121957150 121988558 122207443 122312376 122318014 122552454 122560335 122570540 122665885 122872651 122876352 122950358 123029433 123219783 123263305 123291670 123343634 123347595 123475111 123528442 123551474 124052223 124070022 124120740 124124172 124217782 124345413 124666434 124730208 124837604 124903335 125134911 125280372 125503681 125846349 126121725 126147667 126212885 126246717 126310083 126348531 126570979 126681492 126705180 126715264 126718462 126731508 126734849 127083525 127366051 127810595 127815798 127838841 127843100 127897835 128259900 128275887 128313533 128524321 128598325 128607987 128638597 128842172 128982969 129054185 129138139 129213274 129223736 129300414 129501204

4 3.4 3 3.16667 5.5 5.8 3.75 5.5 3.4 6 6.5 7.25 7.66667 3.8 7.25 5.5 5.6 4.33333 6 5 5.5 13.5 6 4.66667 5 6 5 12.5 4.75 4.75 3.8 3.8 4.75 21.5 5.75 10.5 3 6.33333 3.4 4.75 3.75 6.5 7.5 6 7 4 5.25 4.66667 5.75 5.5 5 6 5.5 7 6 4.66667 4.25 6.33333 13 6 5 5.25 4 5.5 8.5 4.5 6 8.5 6.5 7.5 4.4 5.5 8 3 5.5 3.83333 5.2 6.5 6.5 3.8 6 6.5 5 4.75

ENSSSCT00000010000 ENSSSCT00000010000 ENSSSCT00000024189 ENSSSCT00000024189 ENSSSCT00000024189 . ENSSSCT00000010004 . . . ENSSSCT00000010011 ENSSSCT00000010011 . . . . . . ENSSSCT00000010022 . . . . . . . . . . . . . . . . ENSSSCT00000031175 . . . ENSSSCT00000030690 ENSSSCT00000010025 ENSSSCT00000010027 . ENSSSCT00000030394 ENSSSCT00000030394 ENSSSCT00000010028 . . . . . . . . . . . . . . . . ENSSSCT00000010034 ENSSSCT00000033438 ENSSSCT00000010041 ENSSSCT00000010041 . . . ENSSSCT00000010043 ENSSSCT00000010043 ENSSSCT00000010043 ENSSSCT00000010044 ENSSSCT00000010044 ENSSSCT00000010044 ENSSSCT00000010044 . . . . . . . .

ENPEP ENPEP ELOVL6 ELOVL6 ELOVL6 . RRH . . . . . . . . . . . SGMS2 . . . . . . . . . . . . . . . . . . . . . . . . PPA2 PPA2 TET2 . . . . . . . . . . . . . . . . . NFKB1 SLC39A8 SLC39A8 . . . . . . PPP3CA PPP3CA PPP3CA PPP3CA . . . . . . . .

intron intron intron intron intron intergenic promoter intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic 3'utr intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intron intron intron intergenic intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

0.154 1.055 0.023 . -0.058 . 0.124 . 0.127 . 0.031 . 0.002 0.012 . -0.032 0.128 0.202 -0.038 -0.043 -0.107 . 0.02 . . . -0.007 0.449 -0.091 0.152 . 1.074 0.141 0.102 -0.258 . 0.266 -0.28 0.225 . 0.148 -0.1 0.38 -0.139 0.167 0.643 -0.096 0.016 . . . . -0.11 0.251 -0.062 0.068 . -0.09 0.245 . 0.075 0.197 . . -0.005 0.35 0.027 0.053 . 0.129 0.331 . 0.051 0.2 -0.083 -0.275 . -0.044 . . -0.186 -0.069 . 0.098

308348 rs7935 rs786399137 . . . rs792340338 rs792431228 . rs790804683 rs787964174 699918 rs7914 444518 rs7881 rs787441065 502571 rs7920 rs789408800 rs793128255 rs791222352 rs787719870 . . . rs690951549 . rs788426830 907228 rs7897 rs789594708 323753 rs7928 rs791708142 rs786213351 397161 rs7881 rs790067518 rs792545743 rs787481693 . rs788928491 rs789490245 677350 rs7884 rs787939190 rs792455631 rs791886914 554906 rs7896 921245 rs7907 077409 rs7921 rs791613162 . rs792362005 rs791018284 770982 rs7902 rs702742457 rs787024596 746590 rs7882 183644 rs7900 . 560950 rs7905 rs793680475 rs792888887 732695 rs7905 rs788751601 rs789896356 rs790338014 rs789518099 702238 rs7869 . rs788752996 rs792371269 507703 rs7911 rs697337693 rs788271575 rs786365754 788974 rs7924 rs789185882 rs786460499 . rs792197841 . rs789124095 rs793412063 rs787556310 818737 rs7910 rs792745686 rs792896547 509494 rs7911 rs791111340 rs791977224

2 2 2 2 4 2 2 4 2 2 2 2 3 2 2 2 2 2 4 3 2 2 4 2 2 2 2 2 2 2 3 2 2 4 2 4 2 3 2 2 2 2 3 2 4 2 3 4 2 2 2 2 2 2 2 2 2 2 4 4 2 2 2 2 2 2 2 2 3 2 2 2 4 2 4 2 2 4 4 2 3 4 2 2

AAAAT.ATTTT AAAAG.CTTTT AATC.GATT AAAG.CTTT AAAG.CTTT AG.CT AG.CT AAAG.CTTT AC.GT AAAC.GTTT AAAC.GTTT AAAC.GTTT AT.AT AAC.GTT AC.GT AAAC.GTTT AAAAAC.GTTTTT AC.GT AAAC.GTTT AC.GT AAAAC.GTTTT AT.AT AT.AT AAAAAC.GTTTTT AAAT.ATTT AG.CT AT.AT AG.CT AC.GT AC.GT AG.CT AG.CT AAAAAG.CTTTTT AAAAAT.ATTTTT AT.AT AAAAC.GTTTT AAAAAC.GTTTTT AC.GT AAC.GTT AG.CT AC.GT AAAAC.GTTTT AG.CT AAAT.ATTT AC.GT AAATT.AATTT AAAC.GTTT AAC.GTT AC.GT AAAC.GTTT AC.GT AAAAC.GTTTT AT.AT AT.AT AATC.GATT AC.GT AAAG.CTTT AAT.ATT AG.CT AT.AT AG.CT AAAAT.ATTTT AAAAC.GTTTT AT.AT AAAC.GTTT AAACC.GGTTT AGATG.CATCT AAAT.ATTT AAC.GTT AAC.GTT AAC.GTT AAAC.GTTT ACC.GGT AAAC.GTTT AAAAC.GTTTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAC.GTTT ACAT.ATGT AC.GT AAAT.ATTT AT.AT

8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8

129573492 129728627 129742305 130071388 130122592 130425448 130425448 130481122 130598786 130661440 130713399 130796855 130811814 131119582 131229768 131246100 131319057 131453819 131545816 131632835 131677428 131782234 131868194 131874434 132070588 132110619 132432111 132446599 132450737 132456993 132470931 132500016 132617127 132688251 132714990 132760578 132764073 132792621 132962596 133076000 133162502 133354566 133391378 133441078 133584492 133691017 133758675 133903189 133931299 133939986 133954187 134018015 134067146 134207714 134217312 134247603 134276075 134292660 134303322 134538343 134620761 134630687 134818232 134890000 134947581 134973938 135091352 135117191 135335551 135360267 135448936 135494828 135506899 135523424 135526749 135620968 135639602 135732106 136000258 136079092 136143443 136145749 136232640 136247433

129573514 129728647 129742325 130071400 130122618 130425467 130425467 130481144 130598798 130661481 130713417 130796875 130811831 131119598 131229793 131246127 131319080 131453829 131545834 131632847 131677448 131782243 131868217 131874459 132070602 132110641 132432121 132446609 132450756 132457031 132470944 132500025 132617155 132688279 132714999 132760601 132764100 132792634 132962619 133076009 133162525 133354584 133391388 133441100 133584504 133691031 133758693 133903205 133931311 133940000 133954196 134018034 134067157 134207728 134217336 134247621 134276094 134292676 134303334 134538357 134620773 134630716 134818288 134890019 134947600 134973966 135091373 135117212 135335564 135360282 135448955 135494842 135506912 135523449 135526768 135620984 135639623 135732119 136000271 136079107 136143461 136145761 136232663 136247443

4.6 4.2 5.25 3.25 6.75 10 10 5.75 6.5 10.5 4.75 5.25 9 5.66667 13 7 4 5.5 4.75 6.5 4.2 5 12 4.33333 3.75 11.5 5.5 5.5 10 19.5 7 5 4.83333 4.83333 5 4.8 4.66667 7 8 5 12 3.8 5.5 5.75 6.5 3 4.75 5.66667 6.5 3.75 5 4 6 7.5 6.25 9.5 5 5.66667 6.5 7.5 6.5 6 11.4 10 5 5.8 4.4 5.5 4.66667 5.33333 6.66667 3.75 4.66667 6.5 4 4.25 5.5 3.5 3.5 4 4.75 6.5 6 5.5

. . ENSSSCT00000010051 ENSSSCT00000010052 ENSSSCT00000010053 ENSSSCT00000027188 ENSSSCT00000010057 ENSSSCT00000010059 ENSSSCT00000032198 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000028459 ENSSSCT00000034827 ENSSSCT00000034827 ENSSSCT00000034827 ENSSSCT00000034827 ENSSSCT00000034827 . . . . . . . ENSSSCT00000010065 . . . . . . . . . . ENSSSCT00000026735 ENSSSCT00000026735 ENSSSCT00000026735 ENSSSCT00000026735 ENSSSCT00000026735 . . . . . . . . .

. . H2AFZ . . ADH4 ADH4 METAP1 EIF4E . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . BMPR1B BMPR1B BMPR1B BMPR1B BMPR1B BMPR1B . . . . . . . PDLIM5 . . . . . . . . . . . . . . . . . . . . . . . .

intergenic intergenic promoter intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

0.243 . 0.163 0.128 . . . 2.43 0.241 0.111 . . -0.056 . . 0.234 0.396 0.205 0.125 . 0.345 0.073 0.388 -0.214 . -0.045 0.004 -0.023 0.074 -0.11 0.039 -0.045 -0.131 -0.128 0.281 0.149 0.091 -0.064 0.167 -0.235 -0.1 0.753 0.156 0.02 -0.034 0.054 . 0.145 0.213 0.044 . . . -0.092 . 0.085 0.227 0.133 0.224 0.239 0.111 -0.002 . . . . 0.101 . -0.288 0.157 0.152 0.13 -0.158 . 0.452 0.25 -0.113 -0.005 -0.062 . -0.128 . . -0.02

784192 rs7903 rs786226896 rs786565737 . 590964 rs7911 rs792145086 rs792145086 rs791881328 rs790624688 539036 rs7869 . 200065 rs7882 622110 rs7887 rs786900454 rs693393275 rs793021392 rs789776801 . 357029 rs7876 rs791754492 562512 rs7894 rs791079084 008596 rs7879 rs788152396 952424 rs7879 353624 rs7043 . . rs792078813 rs789089957 rs792143943 . rs791688841 rs789382846 rs791751981 rs791804922 172418 rs7869 rs787898179 rs792150334 rs787275305 rs790660216 rs788876985 rs786740838 rs786254344 rs789863045 rs790101000 rs793860508 310831 rs7884 rs788421242 101528 rs7871 rs792437659 426428 rs7913 rs790106764 . rs790442598 . rs790543115 rs787929999 . . 582613 rs7917 379802 rs7875 rs790587863 rs792751099 321052 rs7872 rs789009715 710285 rs7870 551254 rs7924 rs789754043 rs790472910 rs790778411 rs791663669 rs789642818 rs792473506 318035 rs7890 rs787594597 rs788492847 rs787347740 327060 rs7867 rs790191226 rs788406326 . . .

2 3 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 3 3 2 4 2 2 2 2 2 2 2 2 2 2 2 2 3 2 3 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2

AAG.CTT AAAC.GTTT AT.AT AAAG.CTTT AAAT.ATTT AAAC.GTTT AC.GT ATC.GAT AAAAC.GTTTT AC.GT AAAT.ATTT AC.GT AAAC.GTTT AG.CT AC.GT AAAC.GTTT AAAT.ATTT AAAC.GTTT ACAG.CTGT AAT.ATT AG.CT AAAAT.ATTTT AAAGG.CCTTT AAAAC.GTTTT AAAAC.GTTTT AAAC.GTTT AG.CT AC.GT AC.GT AC.GT AAT.ATT AC.GT AAAAC.GTTTT AAT.ATT AAAC.GTTT AAC.GTT AAC.GTT AAC.GTT AAG.CTT AACC.GGTT AG.CT AG.CT AAAC.GTTT AAC.GTT AAAT.ATTT AAAT.ATTT AC.GT AAC.GTT AAC.GTT AAC.GTT AAGG.CCTT AC.GT AAAT.ATTT AT.AT AAAAT.ATTTT AAG.CTT AAAT.ATTT AAC.GTT AC.GT AATG.CATT AAAC.GTTT AAAAC.GTTTT AAT.ATT AC.GT AAC.GTT AAAT.ATTT AT.AT ACAT.ATGT AG.CT AAAC.GTTT AAT.ATT AC.GT AAAAT.ATTTT AAAC.GTTT AT.AT AG.CT AAAC.GTTT AC.GT AAC.GTT AAT.ATT AT.AT AT.AT AAAT.ATTT AC.GT

8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8

136326450 136401759 136880133 136987542 137040327 137278190 137450795 137468176 137479958 137480758 137666567 137667262 137723194 137759491 137840938 137856724 138227573 138263949 138528956 138688062 138862754 138926985 139039117 139070763 139091756 139097517 139299019 139322497 139488712 139494901 139551433 139590204 139591565 139701408 139851574 139900485 140100877 140100877 140305320 140377642 140537628 140547591 140607149 140768798 141247647 141461072 141942458 142076573 142076573 142076573 142167628 142235119 142476329 142836952 142846620 143117909 143173278 143428066 143498788 143723466 143856601 144045929 144051603 144098427 144144579 144182011 144591216 144777080 145011346 145099808 145142060 145182291 145482655 145484539 145794180 145928478 145990266 146396283 146426484 146732490 146817392 146817392 147023103 147306470

136326464 136401779 136880143 136987555 137040341 137278208 137450811 137468193 137479980 137480768 137666593 137667272 137723212 137759504 137840949 137856748 138227594 138263966 138528970 138688077 138862765 138927001 139039133 139070797 139091795 139097538 139299028 139322508 139488724 139494919 139551446 139590215 139591592 139701430 139851586 139900498 140100903 140100903 140305333 140377653 140537639 140547602 140607170 140768825 141247665 141461097 141942467 142076597 142076597 142076597 142167644 142235131 142476346 142836961 142846638 143117924 143173298 143428083 143498806 143723491 143856619 144045952 144051618 144098437 144144592 144182024 144591227 144777093 145011358 145099830 145142073 145182303 145482675 145484562 145794199 145928491 145990284 146396299 146426496 146732510 146817406 146817406 147023133 147306486

5 5.25 5.5 3.5 3.75 4.75 8.5 6 4.6 5.5 6.75 5.5 4.75 7 6 6.25 5.5 4.5 3.75 5.33333 6 3.4 3.4 7 8 5.5 5 6 6.5 9.5 4.66667 6 5.6 7.66667 3.25 4.66667 9 9 4.66667 3 6 6 5.5 9.33333 4.75 6.5 5 8.33333 8.33333 8.33333 4.25 6.5 4.5 5 3.8 5.33333 5.25 6 9.5 6.5 4.75 4.8 5.33333 5.5 4.66667 3.5 6 3.5 6.5 5.75 4.66667 6.5 4.2 6 10 7 4.75 8.5 4.33333 7 7.5 7.5 7.75 8.5

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000031781 . intron ENSSSCT00000031781 . intron ENSSSCT00000031781 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000010075 MMRN1 intron ENSSSCT00000010077 SNCA intron . . intergenic . . intergenic . . intergenic ENSSSCT00000010079 . promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000022397 . intron ENSSSCT00000010082 HERC3 intron . . intergenic ENSSSCT00000036615 ABCG2 promoter ENSSSCT00000036669 ABCG2 promoter . . intergenic . . intergenic ENSSSCT00000010099 DSPP intron . . intergenic ENSSSCT00000010101 SPARCL1 intron ENSSSCT00000010104 HSD17B13 intron . . intergenic ENSSSCT00000029989 PTPN13 intron . . intergenic ENSSSCT00000036195 MAPK10 intron ENSSSCT00000033080 MAPK10 intron ENSSSCT00000010107 MAPK10 intron ENSSSCT00000010108 ARHGAP24 intron ENSSSCT00000010108 ARHGAP24 intron ENSSSCT00000010108 ARHGAP24 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000010110 CDS1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000010121 COPS4 intron ENSSSCT00000010124 SEC31A intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000022547 PRDM8 intron ENSSSCT00000010135 PRDM8 intron . . intergenic . . intergenic

0.013 0.389 . . -0.052 0.447 -0.107 . -0.017 0.027 -0.111 0.6 0.075 0.218 0.106 0.448 . -0.129 -0.011 . 0.046 0.032 0.084 0.209 . 0.083 0.115 0.024 -0.002 0.169 0.054 . 0.05 0.075 . 0.212 . . 0.129 0.324 -0.024 . 0.231 0.491 . 0.221 -0.014 0.037 0.037 0.037 -0.068 -0.009 . . 0.158 . 0.286 . 0.059 0.25 0.555 0.094 0.015 0.647 . 0.111 0.321 0.25 0.065 . 0.057 . 0.088 0.531 0.189 1.837 0.13 . -0.16 0.002 . . 0.113 0.153

736773 rs7867 rs789874095 761360 rs7886 630422 rs7059 272497 rs7890 519299 rs7899 . rs787774716 615499 rs7899 . rs790156220 rs788353302 rs696068555 190472 rs7927 rs792867535 700994 rs7886 rs791692403 584602 rs7893 302477 rs7897 611642 rs7926 . 839728 rs7869 rs790292379 rs786915821 rs787720917 rs787445639 . 101563 rs7904 226237 rs7896 rs793765403 541429 rs7864 904352 rs7923 929806 rs7862 557547 rs7904 932493 rs7892 rs790109048 575612 rs7865 575612 rs7865 rs786771185 rs791114600 rs790583342 . . rs792080054 . rs793781640 rs788147165 rs789549521 rs789549521 rs789549521 rs787763054 575468 rs7925 rs787028153 rs791855715 rs786365970 . . rs788495553 rs789107945 rs790159325 922500 rs7885 rs793297366 rs790785691 . 641935 rs7889 rs704868975 774307 rs7908 rs793165680 rs791082126 903142 rs7883 . 781747 rs7899 rs788453808 949092 rs7891 861014 rs7926 . rs787390905 rs786988531 . rs789683448 824627 rs7896 824627 rs7896 074334 rs7906 rs787242962

2 2 2 2 2 2 2 2 2 2 2 3 2 2 4 2 2 2 2 2 4 2 3 2 2 2 2 3 2 3 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 3 4 4 4 2 2 3 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 3 2 2 2 2

AC.GT AT.AT AAC.GTT AAAC.GTTT AT.AT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AAAAG.CTTTT AC.GT AAAC.GTTT AC.GT AAAT.ATTT AT.AT AC.GT AAAT.ATTT AAAC.GTTT AAC.GTT AC.GT AC.GT AAAC.GTTT AT.AT AAAAC.GTTTT AATT.AATT AT.AT ACAT.ATGT AC.GT AAAC.GTTT AT.AT AC.GT AG.CT AC.GT AAAAT.ATTTT AC.GT AC.GT AC.GT AT.AT AAAGC.GCTTT AAAT.ATTT AAAAC.GTTTT AAGG.CCTT AAAC.GTTT AAAC.GTTT ACC.GGT ACC.GGT ACC.GGT AT.AT AC.GT AAAC.GTTT AAAAC.GTTTT AC.GT AC.GT AAC.GTT AAAC.GTTT AAAAT.ATTTT AC.GT AC.GT AAC.GTT AAAGC.GCTTT AG.CT AAAAAC.GTTTTT AC.GT AGAT.ATCT AAAAAT.ATTTTT AAT.ATT AT.AT AAAC.GTTT AAC.GTT ACT.AGT AAAG.CTTT AC.GT AAC.GTT AT.AT AT.AT AC.GT AAAC.GTTT AC.GT AG.CT AG.CT AAAC.GTTT AC.GT AAAG.CTTT AAC.GTT AC.GT

8 8 8 8 8 8 8 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9

147371100 147395068 147486895 147682821 147787496 147957689 148213382 300698 2317987 2547460 2740055 2809285 2914966 2923026 2933906 2954688 3043984 3348271 3453243 4286814 5344642 5657795 5674091 5921161 5972417 6042573 6141694 6249758 6561161 6575896 6795076 6818212 6915060 7053879 7065708 7124760 7144142 7153308 7157918 7269515 8085892 8264503 8264503 8308020 8308020 8308020 8655157 8743881 8774688 8813701 9129489 9156131 9514098 9607579 9641780 10777516 11086909 11379554 11411967 11656368 11845595 12248858 12382919 12624520 12731506 12848247 12963737 13394131 13846859 14039798 14074989 14106368 14109433 14167652 14462973 14476013 14910807 15054050 15367511 15372465 15645702 15679706 15897197 15942921

147371113 147395078 147486914 147682845 147787514 147957704 148213400 300716 2318002 2547473 2740073 2809301 2914980 2923041 2933932 2954701 3044001 3348282 3453253 4286823 5344656 5657805 5674113 5921179 5972427 6042595 6141706 6249774 6561174 6575914 6795089 6818221 6915081 7053890 7065722 7124770 7144152 7153323 7157938 7269540 8085922 8264514 8264514 8308036 8308036 8308036 8655168 8743891 8774710 8813716 9129505 9156143 9514109 9607597 9641803 10777525 11086922 11379567 11411992 11656382 11845613 12248872 12382951 12624543 12731533 12848256 12963762 13394145 13846872 14039824 14075000 14106381 14109461 14167662 14462986 14476027 14910817 15054063 15367524 15372479 15645722 15679719 15897213 15942941

7 5.5 6.66667 6.25 9.5 4 4.75 3.8 3.2 7 4.75 8.5 3.75 8 13.5 3.5 4.5 4 5.5 5 3.75 5.5 4.6 4.75 5.5 5.75 6.5 4.25 7 9.5 7 5 4.4 6 7.5 5.5 5.5 3.2 5.25 5.2 7.75 3 3 5.66667 5.66667 5.66667 6 5.5 5.75 3.2 8.5 6.5 4 4.75 4.8 5 7 4.66667 5.2 7.5 3.16667 7.5 8.25 4 9.33333 5 6.5 5 4.66667 6.75 6 4.66667 14.5 5.5 7 3.75 5.5 7 7 3.75 10.5 3.5 5.66667 10.5

. . . . . . ENSSSCT00000010143 . ENSSSCT00000032189 . ENSSSCT00000015949 ENSSSCT00000015949 . . . . . . . . . . . . . . ENSSSCT00000016119 . . . . ENSSSCT00000016142 ENSSSCT00000016143 ENSSSCT00000016143 . ENSSSCT00000016145 ENSSSCT00000016145 ENSSSCT00000016145 ENSSSCT00000016145 . ENSSSCT00000016169 ENSSSCT00000016171 ENSSSCT00000016172 ENSSSCT00000016171 ENSSSCT00000016172 ENSSSCT00000020569 ENSSSCT00000016174 . . . . ENSSSCT00000016185 . . . . ENSSSCT00000016213 ENSSSCT00000025652 ENSSSCT00000025652 ENSSSCT00000016218 . ENSSSCT00000023312 ENSSSCT00000016229 ENSSSCT00000016230 ENSSSCT00000016231 . . . . ENSSSCT00000016246 ENSSSCT00000016246 ENSSSCT00000016246 ENSSSCT00000016246 ENSSSCT00000016248 ENSSSCT00000016249 ENSSSCT00000016249 . . . . . . . .

. . . . . . CSN1S1 . OVCH2 . SYT9 SYT9 . . . . . . . . . . . . . . TRIM68 . . . . . STIM1 STIM1 . NUP98 NUP98 NUP98 NUP98 . STARD10 FCHSD2 FCHSD2 FCHSD2 FCHSD2 U6 . . . . . UCP2 . . . . MAP6 UVRAG UVRAG PRKRIR . . MYO7A . . . . . . GAB2 GAB2 GAB2 GAB2 NARS2 . . . . . . . . . .

intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intron intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic 3'utr intron intron intergenic intron intron intron intron intergenic intron intron intron intron intron promoter intron intergenic intergenic intergenic intergenic promoter intergenic intergenic intergenic intergenic intron intron intron intron intergenic intron intron intron intron intergenic intergenic intergenic intergenic intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

0.034 . . 0.216 0.138 0.266 -0.07 0.32 0.135 -0.059 . 0.282 0.13 . 0.312 . 0.376 . . . . 0.007 -0.099 . -0.009 -0.074 0.391 0.049 -0.519 . . 0.207 0.481 0.243 0.284 . . -0.047 0.3 . 0.164 0.345 0.345 . . . 0.196 0.708 0.382 0.262 0.129 . . . . -0.358 0.097 -0.104 . 0.142 . . 0.046 . . . . 0.127 0.217 . 0.14 . . . 0.093 . 0.094 0.347 -0.001 -0.097 -0.1 -0.104 . -0.046

rs791028159 642026 rs7878 465691 rs7870 917046 rs7870 . rs788337022 rs790219149 rs791291749 rs791651133 458489 rs7866 rs791337645 620079 rs6961 rs791215351 rs789350881 033295 rs7871 . 286201 rs7866 592543 rs7922 . . rs790277652 rs789974413 517684 rs7892 . . 767949 rs7904 331730 rs7876 rs791993539 rs786726445 . rs694452350 rs788449837 rs787365479 rs793816607 rs793148982 rs791067197 rs788731116 rs789190428 rs791994375 rs792111651 rs791761170 rs787321263 rs787321263 rs790120607 rs790120607 rs790120607 rs789342938 . rs787227863 rs787154286 rs710761134 680769 rs7912 rs787153031 rs787677659 234679 rs7891 rs789445648 . rs789732243 rs788546334 rs786947500 893696 rs7925 . rs791257542 rs787307793 rs787882344 rs691967153 rs792029980 . . rs787535301 rs792638897 975109 rs7880 503613 rs7892 rs792842559 rs790457535 738849 rs7908 rs708830826 137703 rs7900 562535 rs7903 . rs793264184 . 526474 rs7877 rs789973187

5 2 2 2 4 2 2 2 2 2 2 7 2 3 2 2 2 2 2 3 4 3 2 2 5 2 2 2 2 2 2 3 2 2 2 2 3 2 2 3 2 2 2 2 2 2 2 2 2 2 4 4 2 2 2 2 4 4 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 4 3

AAC.GTT AAAAC.GTTTT AAAAT.ATTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AATT.AATT AT.AT AG.CT AAAT.ATTT AAAAT.ATTTT AC.GT AAAC.GTTT AC.GT AT.AT AAAAC.GTTTT AC.GT AAAAAC.GTTTTT AAG.CTT AAT.ATT AT.AT AC.GT AT.AT AAT.ATT AT.AT AGAT.ATCT AAT.ATT ACAG.CTGT AC.GT AAAT.ATTT AG.CT AC.GT AAATAT.ATATTT AC.GT AAT.ATT AAAT.ATTT AC.GT AC.GT AAT.ATT AT.AT AC.GT AGG.CCT AT.AT AAAG.CTTT AG.CT AAAC.GTTT AG.CT AC.GT AG.CT AAAC.GTTT AAC.GTT AAAC.GTTT AAC.GTT AT.AT AAAC.GTTT AAAT.ATTT AATG.CATT AC.GT AC.GT AAAT.ATTT AAAAG.CTTTT AGC.GCT AAAC.GTTT AG.CT AAAAC.GTTTT AAAT.ATTT AT.AT AAT.ATT AT.AT AAT.ATT AAC.GTT AAAAAC.GTTTTT AAAC.GTTT AAAC.GTTT AAG.CTT AG.CT AAAC.GTTT AAGAG.CTCTT AC.GT AAT.ATT AC.GT AT.AT AT.AT

9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9

16100769 16179071 16414481 16519206 16581117 16774642 16841095 16871993 16891732 16965862 16977593 17041154 17197722 17224074 17233545 17254194 17317134 17345180 17420122 17442721 17453106 17760784 17800933 17912458 17974204 18053116 18071795 18086626 18535514 18652858 18794021 18891430 19055311 19173757 19352645 19353649 19987927 20004158 20385667 20497885 20578802 20598449 20616601 20790986 20794357 20957929 20972178 21062424 21311578 21554830 21811940 21879793 21975380 22117538 22204434 22314175 22358142 22708034 23121517 23315753 23584999 23829317 23924122 24194356 24332048 24470844 24494387 24856785 25242353 25508087 25684852 25967453 26013910 26037758 26074035 26139168 26144544 26179547 26210481 26449223 26917237 26954556 26960612 27446775

16100790 16179094 16414500 16519233 16581140 16774654 16841121 16872009 16891743 16965887 16977611 17041184 17197740 17224097 17233572 17254204 17317151 17345191 17420143 17442748 17453125 17760794 17800964 17912471 17974215 18053131 18071806 18086655 18535527 18652867 18794043 18891440 19055325 19173775 19352655 19353663 19987947 20004177 20385676 20497896 20578814 20598464 20616619 20790995 20794370 20957940 20972196 21062434 21311588 21554839 21811953 21879807 21975406 22117554 22204443 22314200 22358163 22708054 23121529 23315773 23585025 23829341 23924138 24194378 24332062 24470873 24494402 24856806 25242367 25508098 25684871 25967469 26013932 26037781 26074056 26139190 26144555 26179563 26210510 26449257 26917250 26954566 26960623 27446784

7.33333 4.8 4 7 6 3.25 6.75 4.25 6 13 4.75 6.2 9.5 6 14 5.5 3.6 6 3.66667 9.33333 6.66667 5.5 16 7 4 8 3 10 3.5 5 5.75 5.5 7.5 3.16667 5.5 5 5.25 10 5 4 6.5 8 6.33333 5 3.5 6 4.75 5.5 5.5 5 3.5 5 6.75 5.66667 5 6.5 5.5 5.25 6.5 10.5 6.75 5 5.66667 5.75 7.5 6 4 11 5 6 6.66667 5.66667 3.83333 6 5.5 7.66667 6 4.25 6 17.5 4.66667 5.5 6 5

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000016253 . . ENSSSCT00000016258 ENSSSCT00000016258 . . . . . . . . . . . . . . . ENSSSCT00000016264 ENSSSCT00000016265 ENSSSCT00000016269 . . ENSSSCT00000030954 . ENSSSCT00000028393 . . ENSSSCT00000016279 . . ENSSSCT00000027396 ENSSSCT00000016281 ENSSSCT00000016281 . ENSSSCT00000016284 . ENSSSCT00000024828 . . . . . . . . . . . . .

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . C11orf82 . . CCDC90B CCDC90B . . . . . . . . . . . . . . . CCDC89 SYTL2 . . . . . . . . RAB38 . . . . . . NOX4 . FOLH1 . . . . . . . . . . . . .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic promoter intron intron intergenic intergenic intron intergenic intron intergenic intergenic intron intergenic intergenic intron intron intron intergenic intron intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

-0.145 0.574 . 0.323 0.514 -0.005 0.031 -0.114 -0.148 -0.343 . . -0.078 0.137 -0.077 -0.105 . . . 1.001 0.731 0.058 0.085 . 0.106 0.013 0.08 0.101 0.078 0.081 . 0.223 0.202 0.446 . . . 0.083 0.056 0.014 . . 0.041 . -0.053 -0.013 0.304 0.627 0.272 . 0.387 0.192 -0.01 0.6 0.027 0.114 0.369 0.071 . 0.336 . 0.072 -0.009 -0.002 0.049 . . 0.97 . 0.139 -0.178 1.391 . . 0.243 0.142 . 0.14 0.021 -0.071 0.033 . -0.172 0.127

rs791597400 rs788872213 rs791366873 560124 rs6907 rs793321828 653973 rs7927 rs790897883 rs791299309 rs793745863 rs789033905 . 526955 rs7922 130228 rs7936 rs788934179 rs789321240 968790 rs7892 rs788861149 066574 rs7937 rs791810169 rs791360309 rs792876857 rs787117180 rs789412245 rs792196535 . . rs787075615 774988 rs7902 rs786603253 . rs793788192 613607 rs7900 130434 rs7902 rs789925290 . rs787176367 rs792095226 rs788213430 . rs787111691 369630 rs7885 . rs791435816 rs787576344 . . rs789229351 . rs786683405 . 098396 rs7875 rs792012926 rs787418326 . . rs786210390 rs788355596 rs791267428 rs789296000 090084 rs7898 rs789112954 834696 rs7863 803036 rs7902 rs793871109 rs793727508 994195 rs7889 112578 rs7937 988239 rs7868 rs789364117 rs788043567 rs792162580 rs787361056 rs793144136 381703 rs7920 673725 rs7922 rs791226822 rs791723340 160744 rs7874 800759 rs7879 411179 rs7005 710599 rs7924 . rs793287660 rs787330328

2 2 2 2 2 2 2 2 3 4 3 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 3 3 2 2 3 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 3 2 2 2 2 2 2 2 2 3 2

AAAT.ATTT AAAC.GTTT AAAG.CTTT AAAT.ATTT AT.AT AG.CT AAAG.CTTT AC.GT AT.AT AAT.ATT AAC.GTT AC.GT AT.AT AAT.ATT AG.CT AG.CT AAAC.GTTT AT.AT AAAT.ATTT AAAG.CTTT AAAAAT.ATTTTT AAAC.GTTT AT.AT AAACC.GGTTT AC.GT AC.GT AC.GT AGC.GCT AG.CT AG.CT AAAC.GTTT AAAAC.GTTTT AAC.GTT AAGG.CCTT AC.GT AC.GT AAAC.GTTT AAAC.GTTT AT.AT AT.AT AAAC.GTTT AAAT.ATTT AAAC.GTTT AAC.GTT AAAC.GTTT ACAT.ATGT AAAAG.CTTTT AC.GT AAAC.GTTT AAAAG.CTTTT AAC.GTT AC.GT AAAC.GTTT AT.AT AT.AT AC.GT AAAT.ATTT AT.AT AAAG.CTTT AAT.ATT AC.GT AGAT.ATCT AAC.GTT AAC.GTT AAT.ATT AAAC.GTTT AAT.ATT AG.CT AG.CT AAAT.ATTT ATCC.GGAT AAG.CTT AAAG.CTTT AATT.AATT AT.AT AATG.CATT AC.GT AC.GT AT.AT AG.CT AAAC.GTTT AAAAC.GTTTT AAAAAT.ATTTTT AT.AT

9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9

27600543 28081753 28126273 28173043 28231737 28287939 28543496 28589697 28621062 28691376 28835976 29516294 29748599 29814619 30573920 30578801 30788859 31132775 31315984 31326747 31418484 31464012 31684352 31713641 31733711 31832001 31897034 31932707 32110505 32204333 32304442 32415772 32784395 32812607 32893375 32918657 32932318 32934107 32982753 32986429 32990760 33127317 33268160 33711766 33765602 33851682 33914344 33946095 33996883 34206128 34364052 34448076 34691063 34863998 34941134 34973412 35042103 35188415 35232074 35395557 35686227 35833309 35948596 36191021 36335030 36364895 37063588 37313644 37313644 37348659 37587476 37946907 38007898 38165449 38171419 38237962 38334488 38439746 38470468 38525151 38645506 38675975 38678323 38696614

27600564 28081777 28126289 28173059 28231769 28287948 28543511 28589726 28621073 28691395 28835999 29516306 29748609 29814642 30573929 30578812 30788880 31132789 31316007 31326758 31418501 31464030 31684362 31713671 31733725 31832011 31897044 31932723 32110517 32204342 32304465 32415794 32784411 32812630 32893388 32918669 32932339 32934126 32982775 32986439 32990787 33127332 33268171 33711779 33765616 33851711 33914360 33946107 33996905 34206147 34364074 34448096 34691089 34864011 34941147 34973455 35042124 35188426 35232093 35395581 35686243 35833334 35948613 36191056 36335054 36364909 37063610 37313654 37313654 37348675 37587498 37946920 38007910 38165473 38171428 38237983 38334497 38439755 38470481 38525188 38645521 38676008 38678344 38696623

5.5 6.25 4.25 4.25 16.5 5 4 15 6 6.66667 8 6.5 5.5 8 5 6 5.5 7.5 6 3 3 4.75 5.5 6.2 7.5 5.5 5.5 5.66667 6.5 5 6 4.6 5.66667 6 7 6.5 5.5 5 11.5 5.5 7 4 3 4.66667 3.75 7.5 3.4 6.5 5.75 4 7.66667 10.5 6.75 7 7 22 5.5 6 5 8.33333 8.5 6.5 6 12 8.33333 3.75 7.66667 5.5 5.5 4.25 5.75 4.66667 3.25 6.25 5 5.5 5 5 7 19 4 6.8 3.66667 5

. . intergenic . . intergenic . . intergenic ENSSSCT00000016292 FAT3 intron ENSSSCT00000016292 FAT3 intron ENSSSCT00000016292 FAT3 intron ENSSSCT00000016292 FAT3 intron ENSSSCT00000016292 FAT3 intron ENSSSCT00000016292 FAT3 intron ENSSSCT00000016292 FAT3 intron . . intergenic . . intergenic ENSSSCT00000016304 KIAA1731 intron ENSSSCT00000016307 C11orf54 intron . . intergenic . . intergenic ENSSSCT00000016322 CWC15 3'utr . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000016328 FAM76B intron . . intergenic . . intergenic ENSSSCT00000016332 MTMR2 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000016334 CCDC82 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000016337 CNTN5 intron ENSSSCT00000016337 CNTN5 intron ENSSSCT00000016337 CNTN5 intron . . intergenic . . intergenic ENSSSCT00000016338 ARHGAP42 intron . . intergenic ENSSSCT00000024893 TRPC6 intron ENSSSCT00000024893 TRPC6 promoter . . intergenic ENSSSCT00000022911 MMP27 intron ENSSSCT00000016346 MMP27 intron . . intergenic . . intergenic ENSSSCT00000016356 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000016357 PDGFD intron ENSSSCT00000016357 PDGFD intron . . intergenic . . intergenic . . intergenic . . intergenic

0.348 0.194 -0.037 . 0.47 0.265 0.07 0.037 0.375 -0.185 -0.2 0.281 . . 0.139 -0.125 -0.053 0.064 0.621 -0.056 0.11 0.267 -0.024 0.046 0.152 0.111 . 0.067 0.311 0.745 0.123 0.077 . -0.159 -0.108 -0.215 0.119 -0.042 . . -0.089 -0.039 . 0.376 -0.121 . . . . . -0.008 -0.165 0.098 -0.048 -0.135 -0.008 0.067 0.076 0.075 -0.212 -0.035 0.021 1.886 0.101 0.286 0.077 . 0.874 0.874 -0.095 0.186 0.118 . 0.381 . -0.103 . -0.006 0.151 -0.123 0.25 0.3 -0.13 .

rs788232719 387032 rs7876 rs791504563 . rs697186427 rs787201920 rs791046313 . rs787508368 150614 rs7903 356697 rs7900 061977 rs7934 rs791659121 rs787040952 095434 rs7932 447264 rs7921 rs792682550 693613 rs7864 rs793308749 rs789915844 . 578310 rs7938 . rs793452394 . . . . rs786831315 rs793874719 rs790671634 rs789526368 rs786381086 097729 rs6973 rs791212794 166524 rs7906 rs790349412 859049 rs7133 . . 381455 rs7876 rs788109172 rs792710642 081099 rs7879 rs786390217 rs787797767 . rs789751856 rs787562307 773905 rs7872 854386 rs7919 . rs787825136 rs789885388 923452 rs7894 rs699194832 rs789567435 rs793477795 rs793121449 rs791596313 . rs789023534 175691 rs7930 139444 rs7899 rs788330488 705019 rs7883 rs787411411 rs791186095 rs791186095 rs786279170 048471 rs7901 rs789903919 079518 rs7889 rs791868284 rs790725554 rs786465387 rs788778050 274802 rs7898 rs788353894 838827 rs7864 rs790709616 . rs789112714 rs786900713

4 2 2 2 2 2 2 2 4 2 2 4 2 2 2 2 2 2 4 2 2 2 3 2 2 2 3 2 2 2 2 2 4 2 2 2 4 4 3 3 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 3 2 2 2 2 4 2 2 2 3 3 2 3 2 2 2 2 3 2 2 2 2 2 2 2 2

AC.GT AG.CT AC.GT AT.AT AAC.GTT AAAATT.AATTTT AC.GT AT.AT AAAC.GTTT AAAG.CTTT AT.AT AGAT.ATCT AAAAC.GTTTT AT.AT AAAAG.CTTTT AAAAAC.GTTTTT AAC.GTT AAAC.GTTT AT.AT AG.CT AG.CT AT.AT AAAG.CTTT AG.CT AG.CT AAAAC.GTTTT AC.GT AG.CT AT.AT AG.CT AAAAT.ATTTT AC.GT AT.AT AAATT.AATTT AAG.CTT AC.GT AG.CT AC.GT AAAC.GTTT AAC.GTT AC.GT AT.AT AATC.GATT AATC.GATT AATC.GATT AATC.GATT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AC.GT AT.AT AAG.CTT AAG.CTT AGGG.CCCT AC.GT AT.AT AAAAC.GTTTT AAAAAC.GTTTTT AG.CT AAAC.GTTT AAG.CTT AAAGC.GCTTT AAC.GTT AC.GT AAC.GTT AG.CT AAAAAC.GTTTTT AAAAG.CTTTT AAC.GTT AAAT.ATTT AC.GT AG.CT AAAC.GTTT AAG.CTT AC.GT AAAAC.GTTTT AAAAC.GTTTT AAAAT.ATTTT AAAAT.ATTTT AAAAAT.ATTTTT AAAC.GTTT AAAC.GTTT AAAT.ATTT

9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9

38716101 38830290 38835362 39103255 39518012 39596985 39677192 39792654 40206974 40999085 41060062 41092555 41259476 41264211 41345409 41889937 41939585 42020323 42065186 42068985 42278783 42720761 42931395 43201317 43201317 43419295 43513844 43701735 43719487 43739553 43897016 44722375 44850667 45059706 45181283 45496104 45558262 45582812 45634803 45660504 45661402 45711050 45737446 45737446 45737446 45737446 45762119 45762119 45762119 45762119 45835273 45844491 45927228 45948403 45962279 46096770 46162039 46221331 46222566 46326058 46661067 46663174 46703314 46847196 46851575 46912979 46958237 47825145 48336468 48479279 48482670 48750827 48773253 48864350 48880189 49103047 49360027 49360027 49362663 49362663 49438394 49464458 49690922 49696807

38716111 38830299 38835397 39103265 39518025 39597017 39677227 39792664 40207000 40999111 41060078 41092582 41259492 41264222 41345427 41889963 41939606 42020345 42065195 42068998 42278794 42720793 42931413 43201328 43201328 43419313 43513879 43701744 43719497 43739575 43897042 44722384 44850695 45059723 45181309 45496122 45558273 45582823 45634823 45660521 45661415 45711060 45737462 45737462 45737462 45737462 45762133 45762133 45762133 45762133 45835283 45844505 45927240 45948420 45962297 46096782 46162050 46221351 46222588 46326068 46661086 46663185 46703331 46847218 46851587 46912997 46958246 47825164 48336497 48479292 48482686 48750847 48773263 48864388 48880200 49103059 49360065 49360065 49362700 49362700 49438421 49464481 49690944 49696822

5.5 5 18 5.5 4.66667 5.5 18 5.5 6.75 6.75 8.5 7 3.4 6 3.8 4.5 7.33333 5.75 5 7 6 16.5 4.75 6 6 3.8 18 5 5.5 11.5 5.4 5 14.5 3.6 9 9.5 6 6 5.25 6 7 5.5 4.25 4.25 4.25 4.25 3.75 3.75 3.75 3.75 5.5 7.5 4.33333 6 4.75 6.5 6 4.2 3.83333 5.5 5 4 3.6 7.66667 6.5 6.33333 5 3.33333 6 4.66667 4.25 10.5 5.5 9.75 4 6.5 7.8 7.8 7.6 7.6 4.66667 6 5.75 4

. . . . ENSSSCT00000027751 ENSSSCT00000027751 ENSSSCT00000027751 ENSSSCT00000027751 ENSSSCT00000016366 . ENSSSCT00000016373 ENSSSCT00000016374 . . . . . . . . . . . ENSSSCT00000029186 ENSSSCT00000016379 . . . . . . . . . . . . . . . . . ENSSSCT00000034031 ENSSSCT00000036483 ENSSSCT00000032935 ENSSSCT00000016411 ENSSSCT00000016411 ENSSSCT00000034031 ENSSSCT00000036483 ENSSSCT00000032935 ENSSSCT00000016413 ENSSSCT00000016413 . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000016437 ENSSSCT00000025641 ENSSSCT00000016437 ENSSSCT00000025641 . . ENSSSCT00000016443 ENSSSCT00000016443

. . . . GRIA4 GRIA4 GRIA4 GRIA4 ELMOD1 . KDELC2 EXPH5 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . NCAM1 NCAM1 NCAM1 NCAM1 NCAM1 NCAM1 NCAM1 NCAM1 TTC12 TTC12 . . . . . . . . . . . . . . . . . . . . . . . . SIK3 SIK3 SIK3 SIK3 . . RNF214 RNF214

intergenic intergenic intergenic intergenic intron intron intron intron intron intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intergenic intergenic intron intron

. 0.141 -0.212 . . . . 0.012 . . 0.511 -0.095 0.31 0.396 -0.036 0.131 . 0.346 . 0.098 . 0.039 0.14 . . 0.213 . -0.01 0.204 -0.022 . 0.261 . 0.274 0.029 . 0.152 0.671 . 0.25 0.165 -0.145 0.861 0.861 0.861 0.861 0.201 0.201 0.201 0.201 0.202 -0.044 . -0.104 -0.058 0.183 0.042 . 0.238 2.652 -0.234 -0.099 0.135 0.157 . 0.006 0.139 0.594 -0.022 0.355 -0.383 0.008 -0.123 0.087 . 0.267 . . . . 0.254 0.12 0.282 .

rs791478261 394301 rs7904 955807 rs7878 rs789143987 283823 rs7915 rs789205783 rs791829801 455645 rs7936 213442 rs7876 rs707461527 rs790261646 rs789193247 rs791931794 . rs787204774 rs791388179 201437 rs7897 945121 rs7873 rs790334887 . rs792992348 rs786873057 498833 rs7929 . . rs790498450 rs787061253 . rs693095242 311601 rs7897 rs704986473 rs791106788 . rs790464637 631386 rs7870 rs708122071 rs786589383 rs786746114 598560 rs7909 rs790449678 rs791450812 rs789990948 rs788095779 rs788095779 rs788095779 rs788095779 962320 rs7904 962320 rs7904 962320 rs7904 962320 rs7904 . 730478 rs7917 rs786990267 rs789892565 rs790440019 . 704739 rs7893 rs703922132 rs786886021 . rs791491049 . rs793194223 705520 rs7903 . rs787721099 . rs788848389 rs791392401 137452 rs7890 056211 rs7920 . rs789192530 rs789547256 rs786878253 . rs789012235 rs789012235 rs790846894 rs790846894 208691 rs7889 909462 rs7932 rs791410222 rs791005933

2 4 4 2 2 2 3 2 2 3 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 4 2 2 4 2 2 2 3 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 3 2 2 2 5 2 2 2 3 2 2 2 2 4 2 4 2 2 2 2 3 2 4 2 2 2 2 2 2 2 2 2 2

AAAT.ATTT AAC.GTT ATC.GAT AG.CT AG.CT AC.GT AAG.CTT AC.GT AC.GT AAAAC.GTTTT AT.AT AAAT.ATTT AAAT.ATTT AAAAT.ATTTT AG.CT AT.AT AAAC.GTTT AG.CT AC.GT AAAC.GTTT AT.AT AC.GT AG.CT AG.CT AAAC.GTTT ACAG.CTGT AACC.GGTT AAAAT.ATTTT AT.AT AAGC.GCTT ACAT.ATGT AC.GT AAAC.GTTT AC.GT AAAC.GTTT AG.CT AC.GT AAAT.ATTT AT.AT AC.GT AC.GT AAAT.ATTT AC.GT AAAAC.GTTTT AAG.CTT AAAAT.ATTTT AAAG.CTTT AAAG.CTTT AAAT.ATTT AAAAC.GTTTT AAAC.GTTT AAAAC.GTTTT AT.AT AT.AT AGG.CCT AC.GT AG.CT AT.AT AAAAG.CTTTT AC.GT AC.GT AC.GT AG.CT AAAAAC.GTTTTT AG.CT AAAC.GTTT AT.AT AC.GT AC.GT AC.GT AGAT.ATCT AC.GT ACC.GGT AC.GT AC.GT AC.GT AC.GT AAAAC.GTTTT AAAG.CTTT AAAG.CTTT AC.GT AC.GT AAAAT.ATTTT AAAC.GTTT

9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9

49766942 49784683 49833527 50169268 50200979 50238178 50282548 50448221 50579539 50582976 50613624 50843964 50843964 51148386 51220153 51293974 51348882 51381860 51476962 51564569 52944347 53117633 53218433 53222065 53421117 53500489 53566884 53807280 53821920 53975964 54147210 54174818 54218127 54222989 54366033 54507041 54775255 54812485 55146003 55187281 55187281 55229087 55251648 55608923 55720796 56000211 56541567 56541567 56595214 56725368 56746945 56780575 57340640 57418027 57422502 57582193 58171085 58400778 58445916 59043411 59348239 59389040 59489872 59537127 60281212 60368557 60463731 60760909 60846338 60894424 61067534 61104905 61399865 61401601 61656518 61983824 62800493 62981165 63122406 63122406 63403179 63907896 63920770 64121538

49766964 49784708 49833546 50169278 50200989 50238188 50282559 50448245 50579552 50582994 50613635 50843981 50843981 51148402 51220163 51293986 51348899 51381871 51476974 51564587 52944359 53117644 53218444 53222078 53421132 53500508 53566905 53807294 53821929 53975976 54147229 54174830 54218143 54223003 54366056 54507052 54775264 54812500 55146016 55187291 55187291 55229104 55251659 55608940 55720818 56000228 56541581 56541581 56595234 56725391 56746967 56780596 57340650 57418036 57422520 57582208 58171099 58400790 58445938 59043425 59348249 59389056 59489891 59537155 60281229 60368572 60463743 60760950 60846348 60894435 61067557 61104916 61399883 61401618 61656532 61983836 62800520 62981182 63122438 63122438 63403190 63907908 63920789 64121565

5.75 8.66667 6.66667 5.5 5.5 5.5 4 12.5 7 3.8 6 4.5 4.5 3.4 5.5 6.5 4.5 6 6.5 4.75 6.5 6 6 7 4 5 5.5 3 5 3.25 5 6.5 4.25 7.5 6 6 5 4 7 5.5 5.5 4.5 6 3.6 7.66667 3.6 3.75 3.75 5.25 4.8 5.75 4.4 5.5 5 6.33333 8 7.5 6.5 4.6 7.5 5.5 8.5 10 4.83333 9 4 6.5 21 5.5 6 6 6 6.33333 9 7.5 6.5 14 3.6 8.25 8.25 6 6.5 4 7

ENSSSCT00000016446 CEP164 intron ENSSSCT00000016446 CEP164 intron . . intergenic ENSSSCT00000016448 . intron ENSSSCT00000016448 . intron . . intergenic . . intergenic ENSSSCT00000016452 TMPRSS4 intron ENSSSCT00000016456 MPZL3 3'utr ENSSSCT00000016456 MPZL3 intron ENSSSCT00000016457 MPZL2 intron ENSSSCT00000027542 IFT46 5'utr ENSSSCT00000028599 ARCN1 promoter . . intergenic . . intergenic . . intergenic ENSSSCT00000016476 DPAGT1 intron ENSSSCT00000016478 HINFP intron ENSSSCT00000016481 CBL intron . . intergenic . . intergenic ENSSSCT00000016497 GRIK4 intron ENSSSCT00000016497 GRIK4 intron ENSSSCT00000016497 GRIK4 intron ENSSSCT00000032235 TECTA intron . . intergenic ENSSSCT00000026020 SC5D intron ENSSSCT00000031058 SORL1 intron ENSSSCT00000031058 SORL1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000016503 CRTAM intron ENSSSCT00000016504 C11orf63 intron ENSSSCT00000025784 C11orf63 intron ENSSSCT00000016504 C11orf63 intron ENSSSCT00000016505 BSX intron . . intergenic . . intergenic . . intergenic ENSSSCT00000016541 VWA5A intron ENSSSCT00000026868 VWA5A intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000016562 . intron ENSSSCT00000016562 . intron ENSSSCT00000016568 ROBO3 intron ENSSSCT00000016577 . intron ENSSSCT00000016580 STT3A intron . . intergenic . . intergenic ENSSSCT00000016600 KIRREL3 intron ENSSSCT00000016600 KIRREL3 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000016610 TMEM45B intron ENSSSCT00000016613 APLP2 intron ENSSSCT00000016616 ZBTB44 intron ENSSSCT00000032122 ZBTB44 intron ENSSSCT00000016619 ADAMTS15 intron . . intergenic . . intergenic . . intergenic

. . . -0.009 -0.113 -0.161 0.129 0.006 0.333 -0.053 0.247 0.519 0.519 . -0.189 . -0.044 -0.084 0.197 . -0.532 0.59 -0.156 1.747 0.048 0.157 0.025 . -0.434 0.558 . -0.04 . . . 0.142 -0.051 0.253 0.023 0.128 0.128 0.6 -0.286 0.132 -0.177 . 0.098 0.098 0.136 . . . . . 1.439 0.435 0.054 . . . . . . . . . . . . . . . . . . . . . . . . . . .

rs789563997 313853 rs7882 990937 rs7912 390363 rs7125 . . rs786614785 . 770427 rs7875 rs787700216 rs788906408 rs787906375 rs787906375 rs791592504 rs792336978 rs788704293 rs787777958 . rs789765203 rs789157038 . rs788885120 rs789939211 rs786290893 rs789070806 011506 rs7902 734646 rs7923 rs790693585 rs787021042 105074 rs7892 045688 rs7864 . rs788743789 rs793223508 rs788379187 rs791322766 066350 rs7876 rs792949313 958272 rs7935 rs787511183 rs787511183 rs788704935 rs793258178 rs787703101 312635 rs7891 rs791019650 rs793408245 rs793408245 546402 rs7871 rs787448823 rs787917629 764760 rs7936 . rs786429265 395489 rs7886 rs787830558 . 428896 rs7864 869280 rs7911 307064 rs7877 rs790437107 rs792300133 rs792969792 534788 rs7930 307621 rs7876 rs791817934 159688 rs7868 . 075319 rs7905 rs697083775 rs793482509 . 552817 rs7926 649152 rs7867 . . 901449 rs7935 657305 rs7928 631602 rs7865 631602 rs7865 . rs788166839 rs787244717 rs789888398

2 2 2 3 4 2 2 2 3 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 4 2 4 2 2 2 2 3 2 2 2 2 3 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 3 2 2 4 2 2 2 2 2 2 2 2 3 2 2 2

AAAC.GTTT AC.GT AGAT.ATCT AAAAC.GTTTT AG.CT AAAAAC.GTTTTT AAAT.ATTT AC.GT AT.AT AAGAGG.CCTCT AAAC.GTTT AC.GT AATC.GATT AAAAT.ATTTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AC.GT AC.GT AATG.CATT AG.CT AAAAT.ATTTT AC.GT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AAAT.ATTT AAAT.ATTT AC.GT AT.AT AAC.GTT ATC.GAT AAAT.ATTT AG.CT AG.CT AAAC.GTTT AC.GT AC.GT AAAAC.GTTTT AAAAAC.GTTTTT AC.GT AG.CT AAAAT.ATTTT AC.GT AC.GT AT.AT AC.GT AAAC.GTTT AAC.GTT AT.AT AAAT.ATTT AC.GT AAG.CTT AAAC.GTTT AAAC.GTTT AATC.GATT AC.GT AAAC.GTTT AC.GT AG.CT AT.AT AC.GT AT.AT AC.GT AAAC.GTTT AAC.GTT AAAC.GTTT AC.GT ATC.GAT AC.GT AAAAG.CTTTT AG.CT AAAC.GTTT AG.CT AAAT.ATTT AAAACT.AGTTTT AAC.GTT AAAG.CTTT AC.GT AAAC.GTTT AAT.ATT AAT.ATT AG.CT AC.GT

9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9

64580888 64637071 64782457 64843884 64987068 65027858 65034095 65111126 65237942 65263431 65278476 65743975 65822788 66213047 66328561 66552413 66584420 66654231 66925457 67139833 67457220 67607549 67826857 67982422 68038737 68765147 69093670 69093670 69969041 70405802 70436021 70470600 70908143 70966784 70993879 71149242 71472095 71489065 71709416 71778670 72281071 72410270 72574540 72665304 72875995 72902796 73000639 73005367 73068705 73073030 73078420 73228050 73288306 73305861 73637225 74112158 74464037 74488139 74523899 75038982 75051972 75230830 75258997 75274162 75310954 75484992 75546068 75607624 75639123 75710416 75853493 75978205 76008247 76091413 76170537 76261173 76464348 76574170 76682149 76742405 77273241 77341068 77368798 77771683

64580902 64637099 64782488 64843906 64987080 65027883 65034108 65111137 65237958 65263473 65278500 65743988 65822811 66213067 66328582 66552425 66584434 66654243 66925469 67139858 67457230 67607566 67826872 67982438 68038757 68765162 69093692 69093692 69969076 70405815 70436036 70470630 70908161 70966797 70993889 71149260 71472107 71489100 71709443 71778693 72281084 72410282 72574567 72665317 72876012 72902805 73000661 73005389 73068737 73073039 73078434 73228078 73288325 73305879 73637246 74112188 74464047 74488161 74523913 75038998 75051984 75230849 75259006 75274179 75310968 75485005 75546092 75607639 75639139 75710426 75853512 75978219 76008267 76091435 76170560 76261190 76464359 76574184 76682163 76742429 77273257 77341097 77368807 77771692

3.75 14.5 8 4.6 6.5 4.33333 3.5 6 8.5 7.16667 6.25 7 6 4.2 5.5 3.25 3.75 6.5 6.5 6.5 5.5 3.6 8 4.25 5.25 3.2 5.75 5.75 18 7 5.33333 10.3333 4.75 7 5.5 4.75 6.5 18 5.6 4 7 6.5 5.6 7 9 5 11.5 5.75 11 5 3.75 14.5 6.66667 4.75 5.5 7.75 5.5 5.75 7.5 8.5 6.5 10 5 9 3.75 4.66667 6.25 8 5.66667 5.5 4 7.5 5.25 11.5 6 3 4 3.75 7.5 6.25 5.66667 10 5 5

. . . . . . . . ENSSSCT00000016622 ENSSSCT00000016622 ENSSSCT00000016622 . . . . . . . . . ENSSSCT00000022758 ENSSSCT00000016627 . . . . ENSSSCT00000024361 ENSSSCT00000025938 . . . . ENSSSCT00000023057 . . . ENSSSCT00000016654 ENSSSCT00000016654 . . ENSSSCT00000016662 . ENSSSCT00000028838 . . . ENSSSCT00000017034 ENSSSCT00000017034 . . . ENSSSCT00000017041 ENSSSCT00000017041 ENSSSCT00000017041 . ENSSSCT00000017060 ENSSSCT00000028859 ENSSSCT00000028859 ENSSSCT00000033340 . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000016680 ENSSSCT00000016680 ENSSSCT00000016680

. . . . . . . . NTM NTM NTM . . . . . . . . . . GLB1L2 . . . . GUCY1A2 GUCY1A2 . . . . SNRPE . . . PIK3C2B PIK3C2B . . LEMD1 . ELK4 . . . C1orf186 C1orf186 . . . SRGAP2 SRGAP2 SRGAP2 . C4BPA CR2 CR2 CR1 . . . . . . . . . . . . . . . . . . . . . . CDK14 CDK14 CDK14

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic promoter intergenic intergenic intergenic intron intron intergenic intergenic intron intergenic intron intergenic intergenic intergenic intron intron intergenic intergenic intergenic intron intron intron intergenic intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron

. . . . . . . . . . . . . . . . . . . . . . . . . . 0.279 0.279 . 0.196 . 0.164 0.178 . . . 0.031 0.615 -0.01 -0.427 -0.067 -0.28 0.187 0.266 -0.093 . . -0.076 . -0.393 0.488 0.076 -0.192 0.16 -0.053 0.115 0.156 0.326 -0.14 0.048 0.624 0.556 -0.042 . 0.016 -0.092 -0.045 . 0.023 -0.13 0.004 . -0.067 -0.347 . . 0.371 . 0.298 0.215 0.04 0.246 . .

rs789974133 rs791013889 248176 rs7919 187378 rs7872 rs793509422 636364 rs7894 rs792129112 . . rs698251682 rs787033686 rs789651972 rs789367313 . 264193 rs7908 rs793546199 rs792632602 . rs706312379 rs792083896 . rs793804745 . rs787747200 rs790975004 rs788994551 901254 rs7901 901254 rs7901 . rs791525943 rs788953329 rs790068581 rs789287067 rs789012955 . rs793212952 rs788259913 rs786754553 . 243548 rs7873 rs793853417 rs692243873 rs792854051 . rs790371111 . rs791086610 rs791251087 411236 rs7867 rs793592742 rs793260342 290770 rs7890 rs790275853 rs788241238 rs788550820 442188 rs7901 rs787583275 037833 rs7896 rs786767276 rs791050818 rs788021079 . . rs708587834 rs793052814 rs789661865 rs791048013 . rs793517484 rs787156089 rs790689585 rs792697806 245423 rs7892 rs789926364 564816 rs7864 rs787310633 rs694693675 rs690021944 rs790581964 rs793315469 rs787119386 717069 rs7868 . rs791743949

2 2 3 2 2 2 2 2 2 2 2 2 3 2 3 2 2 4 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 3 2 2 3 2 2 2 3 2 3 2 2 2 2 2 2 2 2 2 2 2 2 3 3 4 2 3 2 2 5 2 2 2 2 2 2 2 2 3 2 2 2 3 2 2 2 2 2 4 3

AAAC.GTTT AT.AT AAGG.CCTT AT.AT AAG.CTT AT.AT AT.AT AG.CT AAGG.CCTT AC.GT AAAAG.CTTTT AAAAC.GTTTT AAAC.GTTT AGAT.ATCT AGAT.ATCT AAAAT.ATTTT AAAT.ATTT AAT.ATT AG.CT AAC.GTT AAAC.GTTT AAAAC.GTTTT AAC.GTT ATC.GAT ACAT.ATGT AAAAC.GTTTT AAC.GTT AG.CT AT.AT AC.GT AC.GT AAC.GTT ACAT.ATGT AC.GT AAAAC.GTTTT AT.AT AAAC.GTTT AAC.GTT AAAC.GTTT AAC.GTT ACAT.ATGT AAC.GTT AGAT.ATCT AAC.GTT AC.GT AT.AT AC.GT AGAT.ATCT AC.GT AAAAC.GTTTT AT.AT AG.CT AC.GT AAAC.GTTT AAAG.CTTT AT.AT AC.GT AAC.GTT AG.CT AT.AT AG.CT AG.CT AG.CT AG.CT AAG.CTT ATCC.GGAT ATCC.GGAT ATCC.GGAT AAAT.ATTT AAAT.ATTT AAAT.ATTT AC.GT AAT.ATT AAAC.GTTT AAAAC.GTTTT AT.AT AG.CT AAC.GTT AAAAT.ATTTT AC.GT AC.GT AAAC.GTTT AAAAAC.GTTTTT AATT.AATT

9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9

77867483 77931326 77944518 78374389 78443272 78539522 78559071 78863569 79211519 79297795 79300105 79303425 79702735 79813542 79813542 80079885 80084488 80084747 80532456 81514023 81537783 81719290 82277488 82558243 82588465 82752115 83113286 83139318 83367427 84022824 84133248 84317213 84387259 84671054 84787117 84822643 84872138 84879293 85053689 85269497 85471167 85513076 86176104 86178709 86454420 86672864 86674713 86974699 87184700 87228031 87257167 87763573 87825501 87855027 87974855 87979180 88159941 88479607 88479869 88544553 88580265 88642602 88642602 88642602 88843124 88940294 88940294 88940294 89107787 89107787 89107787 89579605 90032373 90197333 90333750 90408763 90471190 91103378 91174317 91418828 91492431 91539836 92220533 92297509

77867501 77931349 77944539 78374399 78443284 78539532 78559085 78863579 79211537 79297822 79300133 79303452 79702757 79813560 79813560 80079903 80084508 80084766 80532470 81514042 81537801 81719317 82277502 82558262 82588485 82752145 83113299 83139330 83367443 84022839 84133258 84317229 84387277 84671069 84787140 84822653 84872157 84879304 85053708 85269515 85471181 85513091 86176136 86178722 86454432 86672874 86674722 86974713 87184710 87228053 87257177 87763587 87825515 87855046 87974866 87979189 88159958 88479626 88479880 88544563 88580277 88642612 88642612 88642612 88843139 88940335 88940335 88940335 89107804 89107804 89107804 89579615 90032387 90197365 90333771 90408774 90471201 91103397 91174336 91418839 91492441 91539862 92220566 92297526

4.75 12 5.5 5.5 4.33333 5.5 7.5 5.5 4.75 14 5.8 5.6 5.75 4.75 4.75 3.8 5.25 6.66667 7.5 6.66667 4.75 5.6 5 6.66667 5.25 6.2 4.66667 6.5 8.5 8 5.5 5.66667 4.75 8 4.8 5.5 5 4 5 6.33333 3.75 5.33333 8.25 4.66667 6.5 5.5 5 3.75 5.5 4.6 5.5 7.5 7.5 5 3 5 9 6.66667 6 5.5 6.5 5.5 5.5 5.5 5.33333 10.5 10.5 10.5 4.5 4.5 4.5 5.5 5 8.25 4.4 6 6 6.66667 4 6 5.5 6.75 5.66667 4.5

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000016690 FAM133B intron ENSSSCT00000036613 CDK6 intron ENSSSCT00000036613 CDK6 intron ENSSSCT00000036613 CDK6 intron . . intergenic ENSSSCT00000024549 HEPACAM2 intron ENSSSCT00000028375 HEPACAM2 intron . . intergenic ENSSSCT00000032573 . promoter ENSSSCT00000032573 . intron . . intergenic ENSSSCT00000016700 CASD1 intron ENSSSCT00000016700 CASD1 intron . . intergenic . . intergenic ENSSSCT00000016706 ASB4 intron . . intergenic . . intergenic ENSSSCT00000016708 DYNC1I1 intron ENSSSCT00000016708 DYNC1I1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000016715 COL28A1 intron ENSSSCT00000016715 COL28A1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000030889 PHF14 cds ENSSSCT00000031171 PHF14 cds ENSSSCT00000032105 PHF14 cds . . intergenic ENSSSCT00000024928 THSD7A intron ENSSSCT00000025355 THSD7A intron ENSSSCT00000016724 THSD7A intron ENSSSCT00000024928 THSD7A intron ENSSSCT00000025355 THSD7A intron ENSSSCT00000016724 THSD7A intron . . intergenic . . intergenic . . intergenic ENSSSCT00000016727 SCIN intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000029225 ETV1 intron . . intergenic . . intergenic

0.216 0.575 0.212 . 0.249 0.316 0.256 . . 0.054 0.908 0.181 . 0.303 0.303 . 2.021 2.077 0.298 . 0.267 . 0.211 0.345 0.029 . . 0.19 0.238 -0.003 1.385 . 0.06 0.05 0.287 . . -0.501 0.28 0.059 . 0.186 0.14 0.069 0.032 0.02 . . . 0.379 0.185 0.742 -0.079 . . 0.092 0.101 . . 0.227 . 2.309 2.309 2.309 . 0.121 0.121 0.121 0.008 0.008 0.008 0.076 0.006 0.146 . 0.267 0.406 -0.094 0.096 . -0.225 0.087 . -0.121

rs789469730 rs789188889 745637 rs7938 . rs788404199 055769 rs7868 236153 rs7909 rs787751365 rs789513491 202735 rs7863 rs792838967 rs789694558 202827 rs7919 rs791948749 rs791948749 rs790622197 . . rs789878003 rs789961539 rs790141777 377614 rs7868 rs791170207 rs702251457 rs710374313 rs789624486 189078 rs7912 . rs790572509 . . rs792677837 rs790464505 . 734990 rs7933 rs789026999 523984 rs7937 . rs789673825 . rs791493941 rs694846967 353238 rs7930 rs792571638 rs788667026 rs789178435 rs790870834 363992 rs7938 rs786706727 rs790154592 762759 rs7883 rs791066314 . rs790894964 rs787297553 . 275569 rs7929 rs789119057 rs788446265 rs787581329 . . . . rs791915238 . . . rs786284705 rs786284705 rs786284705 . rs792405219 rs787398444 rs791288304 rs786498153 rs790059667 rs789121382 rs790488362 rs791779119 rs790945136 240149 rs7927 469294 rs7916 799856 rs7905

2 2 2 2 2 2 4 2 2 3 2 2 2 2 2 2 2 3 2 2 2 3 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 3 2 2 2 2 2 2 2 2 2

AAAC.GTTT AT.AT AAT.ATT ATC.GAT AAAC.GTTT AAAG.CTTT AAAC.GTTT AT.AT AT.AT AT.AT AAAAC.GTTTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAAC.GTTTT AT.AT AT.AT AG.CT AG.CT AT.AT AAAAAG.CTTTTT AT.AT AC.GT AAT.ATT AG.CT AAAC.GTTT AAAAAC.GTTTTT AC.GT AC.GT AG.CT AAAC.GTTT AG.CT AAT.ATT AGG.CCT AT.AT AT.AT AAAT.ATTT AT.AT AAAG.CTTT AC.GT AC.GT AAT.ATT AAAT.ATTT AAAAT.ATTTT AG.CT AC.GT AT.AT AT.AT AAAC.GTTT AAAC.GTTT AC.GT AAAAT.ATTTT AAAC.GTTT AAAC.GTTT AT.AT AC.GT AAAC.GTTT AAT.ATT AC.GT AAAAC.GTTTT AAAAG.CTTTT AAAAC.GTTTT AAAAG.CTTTT AAC.GTT AAC.GTT AAAC.GTTT AC.GT AAAC.GTTT AAAAC.GTTTT AC.GT ATC.GAT AAC.GTT AAC.GTT AAAAT.ATTTT AC.GT AC.GT AT.AT AT.AT AAAC.GTTT AAAAC.GTTTT AAAG.CTTT AAC.GTT AAC.GTT AAAAG.CTTTT

9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9

92491725 92551911 93223373 93249427 93376045 93868217 94127974 94153285 94238610 94239421 94334745 94389448 94576270 94858252 95141258 95172700 95311912 95392308 95392308 95744616 95807836 95876529 95939519 95972995 96012796 96018738 96100711 96202468 96236296 96520749 96561370 96584640 96616191 97075027 97093126 97152962 97292876 97471253 97564524 97798367 98069557 98116403 98177440 98190141 98229597 98314832 98328636 98335899 98456486 98925980 99190973 99234924 99625954 99843986 99880678 99905290 99915095 100003894 100052895 100058648 100059656 100154382 100238989 100280230 100399291 100419459 100434024 100461838 100651812 100859740 101192322 101254353 101254353 101500607 101555684 101717328 102088039 102088039 102170202 102405959 102513674 102618958 102618958 102749507

92491745 92551920 93223386 93249438 93376065 93868243 94127992 94153294 94238622 94239445 94334767 94389469 94576296 94858265 95141277 95172709 95311926 95392318 95392318 95744626 95807878 95876544 95939532 95973007 96012806 96018765 96100733 96202478 96236310 96520763 96561384 96584657 96616214 97075042 97093137 97152973 97292894 97471265 97564543 97798379 98069571 98116419 98177455 98190158 98229633 98314845 98328646 98335915 98456505 98925999 99191006 99234948 99625975 99844002 99880692 99905301 99915106 100003916 100052906 100058666 100059671 100154397 100239015 100280244 100399307 100419486 100434042 100461862 100651840 100859771 101192339 101254366 101254366 101500628 101555698 101717340 102088050 102088050 102170216 102405986 102513697 102618977 102618977 102749526

5.25 5 4.66667 4 5.25 6.75 4.75 5 6.5 12.5 4.6 5.5 6.75 3.5 4 5 7.5 5.5 5.5 5.5 7.16667 8 7 4.33333 5.5 7 3.83333 5.5 7.5 7.5 3.75 9 8 5.33333 6 6 4.75 6.5 5 6.5 7.5 5.66667 4 3.6 18.5 7 5.5 8.5 5 5 17 5 5.5 4.25 7.5 6 3 7.66667 6 3.8 3.2 3.2 5.4 5 5.66667 7 9.5 6.25 5.8 16 6 4.66667 4.66667 4.4 7.5 6.5 6 6 3.75 5.6 6 6.66667 6.66667 4

. . . ENSSSCT00000016731 . . . . . . ENSSSCT00000029064 ENSSSCT00000029064 . . . . . ENSSSCT00000027011 ENSSSCT00000016739 . . . . . ENSSSCT00000029645 ENSSSCT00000029645 ENSSSCT00000029645 . . . . . . . . . . . . . . . . . . . ENSSSCT00000025990 ENSSSCT00000025990 . ENSSSCT00000016752 . . . ENSSSCT00000016754 ENSSSCT00000016754 ENSSSCT00000016754 ENSSSCT00000016754 ENSSSCT00000016754 ENSSSCT00000016754 ENSSSCT00000016754 ENSSSCT00000016754 ENSSSCT00000016754 . . . ENSSSCT00000016758 ENSSSCT00000016758 ENSSSCT00000016758 . . . ENSSSCT00000022993 ENSSSCT00000016761 . ENSSSCT00000030773 ENSSSCT00000029993 ENSSSCT00000026738 ENSSSCT00000030941 . . . ENSSSCT00000016765 ENSSSCT00000034567 ENSSSCT00000016766

. . . . . . . . . . . . . . . . . . . . . . . . SNX13 SNX13 SNX13 . . . . . . . . . . . . . . . . . . . MACC1 MACC1 . ABCB5 . . . DNAH11 DNAH11 DNAH11 DNAH11 DNAH11 DNAH11 DNAH11 DNAH11 DNAH11 . . . RAPGEF5 RAPGEF5 RAPGEF5 . . . FAM126A FAM126A . . IGF2BP3 RUNDC3B RUNDC3B . . . PGP1A PGP1A CROT

intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic promoter promoter intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intron intergenic intergenic intergenic intron intron intron intron intron intron intron intron intron intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intron intron intergenic intron intron intron intron intergenic intergenic intergenic intron intron intron

. -0.172 -0.019 1.27 . -0.017 -0.04 0.059 -0.04 0.217 . 0.026 . -0.191 . 0.086 . . . 0.02 0.01 0.052 . 0.029 . 0.32 . 0.426 . 0.136 0.373 -0.113 . 1.745 . . 0.066 0.185 -0.273 . 0.26 . 0.059 -0.037 0.031 0.051 0.01 0.252 0.16 0.123 0.183 0.274 0.026 . . . 1.63 -0.024 . -0.321 -0.149 0.163 . 0.121 -0.221 0.571 -0.003 -0.044 0.079 . 0.241 0.253 0.253 -0.039 1.359 . . . . . 0.053 0.153 0.153 0.001

rs787689991 rs789683011 rs788235429 . 886044 rs7922 503720 rs7930 rs789282185 rs790581864 . rs790377964 rs789611584 555767 rs7873 . rs792051717 rs793549523 rs790689400 rs792993351 . . 733443 rs7899 145759 rs7934 rs790042417 . rs704451919 . 004535 rs7899 346110 rs7920 rs793395249 871429 rs7916 rs788396659 748442 rs7887 rs788747541 099828 rs7936 rs792427080 . rs789288586 . rs790788601 rs787339683 rs786771774 rs790106814 rs793044333 rs787218709 rs788688215 rs789373164 rs787733015 rs789932055 rs788330170 114895 rs7873 rs789121637 303552 rs7915 766312 rs7863 rs787704710 rs790662068 rs788166128 rs707623446 rs787981669 rs787827182 rs788598533 rs787320055 rs790415367 rs791760435 rs792009992 rs793683589 247264 rs7923 rs789154067 464050 rs7926 rs788295783 rs704208738 rs792884417 rs712173891 rs788169672 rs788169672 rs793106616 rs789712567 rs788299579 rs788349748 rs788349748 rs788164439 rs786208115 rs791834419 533088 rs7872 533088 rs7872 rs787977186

2 3 2 2 2 2 2 3 2 5 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2

AG.CT AAC.GTT AG.CT AAAT.ATTT AAAC.GTTT AT.AT AAAC.GTTT AT.AT AAAT.ATTT AC.GT AAAC.GTTT AAAATT.AATTTT ACAGC.GCTGT AT.AT AAAC.GTTT AAAAT.ATTTT AT.AT AAAC.GTTT AAAC.GTTT AAAT.ATTT AC.GT AAAT.ATTT AAAG.CTTT AAAT.ATTT AAAAC.GTTTT AAAAC.GTTTT AC.GT AAAT.ATTT AAAAC.GTTTT AAAAC.GTTTT AT.AT AGAT.ATCT AT.AT AC.GT AAAC.GTTT AAAC.GTTT AAAC.GTTT AATG.CATT AATG.CATT AATG.CATT AATC.GATT AATC.GATT AATC.GATT AAAT.ATTT AAAT.ATTT AAAT.ATTT AG.CT AG.CT AG.CT AAAC.GTTT AC.GT AT.AT AG.CT AC.GT AG.CT AAAC.GTTT AAT.ATT AAC.GTT AG.CT AAC.GTT AAAG.CTTT AC.GT AAC.GTT ACAT.ATGT AAAT.ATTT AAT.ATT AT.AT AAAAT.ATTTT AAAC.GTTT AAATC.GATTT AT.AT AC.GT AT.AT AGAT.ATCT AAC.GTT AAAT.ATTT AC.GT AAAG.CTTT AG.CT AC.GT AT.AT AAC.GTT AC.GT AAAT.ATTT

9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9

102776582 102807311 102840401 102872469 103136055 103162818 103240726 103322866 103339650 104239688 104270351 104724340 104776819 104787195 104973039 105174814 105249180 105414842 105415109 105476909 105519023 105948548 105961919 105964122 106104161 106345615 106787296 106848109 106862128 107026829 107105502 107149659 107214626 107295342 107378876 107378876 107378876 107466687 107466687 107466687 107478072 107478072 107478072 107638010 107638010 107638010 107724555 107724555 107724555 108001608 108121058 108348579 108355561 108461001 108465182 108634993 108671795 108675004 108753304 109037436 109244937 109248571 109320519 109496277 109554243 109556989 109574148 109606739 109674557 109768642 109808279 109872889 110022962 110280360 110317908 110391209 110461441 110805712 110829433 111029645 111056016 111081517 111196147 111366217

102776596 102807328 102840410 102872493 103136078 103162827 103240744 103322884 103339665 104239707 104270370 104724366 104776836 104787204 104973061 105174831 105249190 105414865 105415129 105476930 105519041 105948562 105961936 105964154 106104198 106345630 106787310 106848128 106862145 107026854 107105528 107149690 107214635 107295351 107378893 107378893 107378893 107466727 107466727 107466727 107478090 107478090 107478090 107638024 107638024 107638024 107724565 107724565 107724565 108001626 108121070 108348602 108355577 108461017 108465203 108635012 108671811 108675029 108753317 109037447 109244949 109248582 109320532 109496316 109554259 109557004 109574157 109606768 109674583 109768664 109808291 109872907 110022979 110280383 110317924 110391228 110461461 110805732 110829454 111029676 111056026 111081535 111196157 111366240

7.5 6 5 6.25 6 5 4.75 9.5 4 10 5 4.5 3.6 5 5.75 3.6 5.5 6 5.25 5.5 9.5 3.75 4.5 8.25 7.6 3.2 7.5 5 3.6 5.2 13.5 8 5 5 4.5 4.5 4.5 10.25 10.25 10.25 4.75 4.75 4.75 3.75 3.75 3.75 5.5 5.5 5.5 4.75 6.5 12 8.5 8.5 11 5 5.66667 8.66667 7 4 3.25 6 4.66667 10 4.25 5.33333 5 6 6.75 4.6 6.5 9.5 9 6 5.66667 5 10.5 5.25 11 16 5.5 6.33333 5.5 6

ENSSSCT00000016766 CROT intron . . intergenic . . intergenic ENSSSCT00000026505 TMEM243 promoter ENSSSCT00000016769 KIAA1324L intron ENSSSCT00000016769 KIAA1324L intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000016771 SEMA3D intron ENSSSCT00000016771 SEMA3D intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000016774 SEMA3E intron ENSSSCT00000016774 SEMA3E intron . . intergenic . . intergenic . . intergenic ENSSSCT00000016776 PCLO intron ENSSSCT00000025400 PCLO intron ENSSSCT00000027728 PCLO intron ENSSSCT00000016776 PCLO intron ENSSSCT00000025400 PCLO intron ENSSSCT00000027728 PCLO intron ENSSSCT00000025400 PCLO intron ENSSSCT00000027728 PCLO intron ENSSSCT00000016776 PCLO intron ENSSSCT00000016776 PCLO intron ENSSSCT00000025400 PCLO intron ENSSSCT00000027728 PCLO intron ENSSSCT00000016776 PCLO intron ENSSSCT00000025400 PCLO intron ENSSSCT00000027728 PCLO intron . . intergenic ENSSSCT00000016777 CACNA2D1 intron ENSSSCT00000016777 CACNA2D1 intron ENSSSCT00000016777 CACNA2D1 intron ENSSSCT00000016777 CACNA2D1 intron ENSSSCT00000016777 CACNA2D1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000016779 . intron ENSSSCT00000016779 . intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000016781 GNAT3 promoter ENSSSCT00000016781 GNAT3 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

. . . -0.005 0.044 0.042 . 0.163 0.147 . -0.079 . 0.613 . -0.118 -0.1 0.046 . . 0.071 0.556 . -0.198 -0.01 0.183 0.051 0.103 0.22 -0.16 0.161 -0.049 . -0.078 -0.061 -0.026 -0.026 -0.026 0.112 0.112 0.112 -0.077 -0.077 -0.077 0.984 0.984 0.984 -0.189 -0.189 -0.189 . -0.136 0.178 -0.117 -0.057 0.031 -0.12 0.036 0.062 -0.249 0.089 . 0.081 . -0.141 . 0.266 0.046 . -0.304 -0.107 0.021 . . 0.178 1.482 0.141 0.034 . . . -0.129 . 0.116 -0.057

rs787370890 500988 rs7898 rs793603397 rs787331612 rs790783040 . rs789227469 948654 rs7890 . 877315 rs7883 rs792914742 rs789990591 rs791546139 . rs788568658 rs793687633 rs793270941 rs792718110 060358 rs7907 rs792718382 rs786705328 . rs789802130 949601 rs7882 rs789247435 rs788809051 . rs787448756 253291 rs7884 rs792290526 rs789085396 651065 rs7880 rs790558264 rs712127363 rs787365383 rs787365383 rs787365383 775943 rs7907 775943 rs7907 775943 rs7907 rs791461415 rs791461415 rs791461415 rs790945519 rs790945519 rs790945519 . . . 182214 rs7898 rs789478293 871146 rs7889 011204 rs7906 rs793693753 . rs786668922 rs792301533 488294 rs7877 rs793533320 rs792993297 . . rs793511566 . rs792335298 rs787494556 . . rs787188557 rs792113163 rs791161182 rs788057266 rs789036241 694677 rs7872 rs790361978 751955 rs7913 . rs789836680 rs791054338 rs695270297 rs788158050 rs792045822 rs790128306 .

2 3 2 2 2 3 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 4 3 2 2 2 3 3 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 5 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 3 2 5 4 2 2 2 2 4 4 2 2 2

AT.AT AAAAC.GTTTT AT.AT AC.GT AT.AT AC.GT AAAC.GTTT AT.AT ATCC.GGAT AT.AT AT.AT AC.GT AAAAC.GTTTT ATC.GAT AAAAT.ATTTT AGG.CCT AAAAAC.GTTTTT AT.AT AAAT.ATTT AAAAT.ATTTT AC.GT AAC.GTT AATG.CATT AACAC.GTGTT AT.AT AAAAAC.GTTTTT AAC.GTT AAAAT.ATTTT AAC.GTT AC.GT AT.AT AAAT.ATTT AGGG.CCCT AC.GT AC.GT AAAAC.GTTTT AAAT.ATTT AATCTC.GAGATT AATT.AATT AAC.GTT AC.GT AAC.GTT AG.CT AC.GT AC.GT AAG.CTT AAG.CTT AC.GT ACAT.ATGT AAAAAG.CTTTTT AAAT.ATTT AG.CT AAC.GTT AC.GT AAC.GTT AC.GT AG.CT AG.CT AAAC.GTTT AAAG.CTTT AAAAAC.GTTTTT AAAT.ATTT AAC.GTT ACGC.GCGT AT.AT AAAAC.GTTTT AT.AT AT.AT AC.GT AT.AT AG.CT AC.GT AAAC.GTTT AG.CT AAAC.GTTT AC.GT AAAT.ATTT AC.GT AAAC.GTTT AAAG.CTTT AT.AT AG.CT AAG.CTT AAAG.CTTT

9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9

111551267 111603527 111852487 111993712 112139058 112331898 112527926 112618603 112629570 112800453 112934143 112948564 112984556 113254398 113279212 113963908 114042552 114139764 114475763 114484669 114652719 114737886 114793222 114870383 115084766 115130564 115213371 115360703 115738369 115939535 115954396 116382157 116611000 116627938 116731437 116761275 116785251 116966742 117049078 117065911 117075630 117280958 117293469 117361566 117446409 117761212 118184124 118273475 118587904 118639713 118671864 118672390 118698801 118711950 119125717 119399924 119560200 119560200 119756493 119931116 120148551 120161309 120188788 120210117 120362600 120428972 120482483 120891798 120915591 120925061 120975017 121114399 121317206 121337217 121369068 121499774 121519107 121533703 121713227 121756397 121785918 121828819 121879046 121894402

111551284 111603543 111852502 111993737 112139069 112331910 112527949 112618625 112629587 112800472 112934158 112948578 112984584 113254409 113279230 113963919 114042579 114139774 114475777 114484684 114652731 114737919 114793251 114870398 115084775 115130592 115213386 115360720 115738396 115939548 115954407 116382174 116611014 116627949 116731446 116761300 116785286 116966763 117049101 117065933 117075639 117280971 117293484 117361578 117446419 117761225 118184135 118273489 118587918 118639736 118671881 118672404 118698824 118711963 119125730 119399940 119560217 119560217 119756504 119931128 120148573 120161325 120188801 120210134 120362611 120429004 120482495 120891808 120915615 120925085 120975030 121114411 121317226 121337229 121369095 121499792 121519130 121533715 121713245 121756420 121785929 121828837 121879077 121894425

9 3.4 8 13 6 6.5 6 11.5 4.5 10 8 7.5 5.8 4 3.8 4 4.66667 5.5 3.75 3.2 6.5 11.3333 7.5 3.2 5 4.83333 5.33333 3.6 9.33333 7 6 4.5 3.75 6 5 5.2 9 3.66667 6 7.66667 5 4.66667 8 6.5 5.5 4.66667 4 7.5 3.75 4 4.5 7.5 8 7 4.66667 8.5 9 9 3 3.25 3.83333 4.25 4.66667 4.5 6 6.6 6.5 5.5 12.5 12.5 7 6.5 5.25 6.5 7 9.5 6 6.5 4.75 6 6 9.5 10.6667 6

. . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000023465 . intron ENSSSCT00000023465 . intron ENSSSCT00000016785 PHTF2 intron ENSSSCT00000016786 PTPN12 intron ENSSSCT00000016786 PTPN12 intron . . intergenic ENSSSCT00000021410 U6 promoter ENSSSCT00000016789 FAM185A intron ENSSSCT00000016801 DNAJC2 intron . . intergenic ENSSSCT00000016805 RELN intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000016806 ORC5 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000032237 SRPK2 intron . . intergenic . . intergenic ENSSSCT00000016812 ATXN7L1 intron . . intergenic ENSSSCT00000022799 . intron ENSSSCT00000016813 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000031097 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000016830 NME8 intron . . intergenic ENSSSCT00000029694 . intron ENSSSCT00000029130 STARD3NL intron . . intergenic . . intergenic . . intergenic ENSSSCT00000031790 ZNF425 intron . . intergenic ENSSSCT00000016835 PDIA4 intron ENSSSCT00000023706 EZH2 intron ENSSSCT00000016837 CUL1 intron ENSSSCT00000031913 . promoter ENSSSCT00000026150 CNTNAP2 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000016840 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000024740 . promoter . . intergenic . . intergenic . . intergenic

0.029 0.134 0.037 0.012 . 0.035 0.33 -0.048 0.026 0.232 . 0.259 . 0.168 0.796 -0.024 0.145 0.55 0.213 0.201 -0.022 . 0.177 -0.124 0.234 0.261 0.18 -0.009 . 0.146 . . -0.206 -0.298 -0.053 -0.175 . . 0.03 0.034 -0.064 0.202 -0.056 0.156 0.174 -0.077 0.186 0.116 0.197 0.039 0.046 0.07 -0.114 0.012 . 0.123 0.687 0.687 -0.007 . . 0.207 . -0.307 0.175 0.009 -0.073 -0.124 -0.087 -0.031 0.214 0.019 . 0.611 -0.068 0.061 -0.136 -0.15 -0.126 -0.162 -0.102 -0.131 . .

rs788081815 rs789760632 . rs790843149 rs789095120 970691 rs7880 974366 rs7930 rs789069308 591722 rs7913 rs787593832 . rs788364518 rs793686386 rs789410460 rs790606571 . rs790447274 . . rs786256585 rs709426894 rs788333118 . . 482433 rs7887 rs788514809 rs788985894 507382 rs7931 rs788424450 rs787128875 . 780155 rs7907 rs792500736 160218 rs7935 rs788102530 179530 rs7911 rs788385082 023735 rs7894 787444 rs7927 rs793702489 . rs790192950 rs787374223 rs793589464 . . 700367 rs7887 rs790559662 . rs791529141 rs790752147 . rs790392335 974415 rs7920 rs789641623 . 363699 rs7919 363699 rs7919 rs789934354 rs789802949 448403 rs7919 rs792769207 574570 rs7877 rs792631106 819465 rs7893 rs790429663 rs788074391 rs793714400 rs793388199 . . rs788682422 087137 rs7909 926691 rs7894 rs793876919 rs791322188 420364 rs7930 . rs792803802 rs791985956 rs788530476 rs787115525 rs788480384 rs789279615

2 2 3 3 2 2 2 2 2 2 2 2 2 2 2 3 2 3 4 2 2 2 2 2 3 2 2 2 2 4 4 2 2 2 2 2 2 2 2 3 4 2 2 4 4 3 2 2 2 2 2 2 5 3 2 3 2 2 2 2 2 2 2 2 2 2 3 2 2 2 4 2 2 2 2 6 2 4 2 2 2 3 2 2

AC.GT AC.GT AAAC.GTTT AG.CT AG.CT AAAC.GTTT AT.AT AAAC.GTTT AG.CT AG.CT AG.CT AAAG.CTTT AAAC.GTTT AG.CT AAGG.CCTT AAAC.GTTT AAAT.ATTT AT.AT AC.GT AAAC.GTTT AT.AT AC.GT AAAC.GTTT AAAG.CTTT AT.AT AAC.GTT AGG.CCT AC.GT AAAAAC.GTTTTT AAG.CTT AT.AT AAAG.CTTT AAAAC.GTTTT AG.CT AG.CT AAAC.GTTT AAAC.GTTT ATC.GAT AAAC.GTTT AAG.CTT AAAC.GTTT AG.CT AC.GT AAAC.GTTT AAC.GTT AAAAC.GTTTT AATG.CATT AAAC.GTTT AC.GT AAAT.ATTT AAAT.ATTT AC.GT AAATT.AATTT AAAG.CTTT AAAC.GTTT AG.CT AAAT.ATTT AG.CT AAGT.ACTT AAAAG.CTTTT ACAG.CTGT ATCG.CGAT AAAAC.GTTTT AC.GT ACAT.ATGT AATAT.ATATT AAAC.GTTT AAAAAC.GTTTTT AATG.CATT AC.GT AAAC.GTTT AAAAG.CTTTT AC.GT AT.AT AT.AT AT.AT ATC.GAT AGG.CCT AG.CT AAAAT.ATTTT AAC.GTT AAC.GTT AGG.CCT AC.GT

9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9

121898766 121954245 122169500 122191020 122282415 122373987 122552454 122652997 122676302 122834528 123050339 123073209 123117940 123279709 123298824 123517703 123542879 123553718 123602640 123695790 123746826 123971705 124222416 124229324 124248102 124594839 124640323 124823055 124872607 124876347 124922610 125043128 125059094 125100348 125100348 125346699 125346699 125365020 125594569 125623365 125688493 125849176 126082907 126088146 126209748 126270451 126455471 126581533 126672946 127104925 127136038 127426556 127480995 127495618 127517766 127624077 127700478 127757181 127895282 127965187 128032636 128128125 128406912 128413324 129172131 129263767 129406015 129533020 129589500 129692484 129761018 129971946 130141729 130214418 130569982 130594623 130618018 130721585 130787839 130892330 131092030 131390568 131503482 131662068

121898777 121954261 122169535 122191044 122282425 122374006 122552467 122653018 122676312 122834550 123050349 123073227 123117982 123279728 123298868 123517724 123542904 123553730 123602650 123695816 123746836 123971715 124222432 124229340 124248119 124594852 124640334 124823071 124872635 124876360 124922619 125043147 125059118 125100357 125100357 125346725 125346725 125365035 125594585 125623381 125688515 125849188 126082919 126088167 126209765 126270479 126455489 126581561 126672956 127104943 127136052 127426581 127481010 127495629 127517780 127624086 127700501 127757190 127895312 127965210 128032666 128128145 128406938 128413342 129172151 129263783 129406033 129533041 129589524 129692508 129761038 129971969 130141744 130214430 130570001 130594645 130618035 130721601 130787848 130892346 131092051 131390583 131503495 131662082

6 8.5 9 12.5 5.5 5 7 5.5 5.5 11.5 5.5 4.75 10.75 10 11.25 5.5 6.5 6.5 5.5 6.75 5.5 5.5 4.25 4.25 9 4.66667 4 8.5 4.83333 4.66667 5 5 5 5 5 6.75 6.75 5.33333 4.25 5.66667 5.75 6.5 6.5 5.5 6 5.8 4.75 7.25 5.5 4.75 3.75 13 3.2 3 3.75 5 6 5 7.75 4.8 7.75 5.25 5.4 9.5 5.25 3.4 4.75 3.66667 6.25 12.5 5.25 4.8 8 6.5 10 11.5 6 5.66667 5 3.4 7.33333 5.33333 4.66667 7.5

. . intergenic ENSSSCT00000016843 . promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000016844 TPK1 intron . . intergenic ENSSSCT00000022548 . promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000016855 . intron ENSSSCT00000016854 . intron ENSSSCT00000016859 CHI3L1 intron ENSSSCT00000036518 CHI3L1 intron . . intergenic . . intergenic ENSSSCT00000016865 VAMP4 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000028491 . intron . . intergenic ENSSSCT00000016869 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000028213 PRDX6 intron ENSSSCT00000016873 SLC9C2 intron . . intergenic ENSSSCT00000016882 KLHL20 intron ENSSSCT00000016876 DARS2 intron ENSSSCT00000016884 RC3H1 intron . . intergenic . . intergenic ENSSSCT00000016886 . intron . . intergenic . . intergenic ENSSSCT00000016895 TNR intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000016896 . intron ENSSSCT00000016896 . intron . . intergenic ENSSSCT00000016899 PAPPA2 intron ENSSSCT00000016899 PAPPA2 intron ENSSSCT00000026733 ASTN1 intron ENSSSCT00000026733 ASTN1 intron ENSSSCT00000026733 ASTN1 intron . . intergenic ENSSSCT00000016902 BRINP2 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000031105 . intron . . intergenic

0.015 -0.062 -0.327 -0.141 0.119 -0.293 -0.403 . -0.103 -0.122 -0.046 . 0 -0.287 -0.265 0.291 0.189 0.174 . -0.185 -0.051 -0.085 0.285 0.247 0.1 -0.119 . . . -0.564 . . . . . . . -0.003 . 0.5 -0.143 -0.206 . 0.17 0.885 -0.028 0.116 0.153 0.196 . -0.23 0.008 . 1.855 0.176 0.18 0.294 0.049 . 0.193 0.055 0.196 0.095 . 0.059 0.113 -0.303 . 0.08 0.129 0.252 . 0.101 0.09 -0.031 -0.044 0.01 -0.18 . 0.379 . 0.569 0.273 .

906042 rs7899 rs790176232 rs705930507 403164 rs7868 . rs789505205 555443 rs7911 rs790526818 rs787609783 . rs790663179 rs788642985 rs792722862 589647 rs7917 rs789178775 rs789920018 rs791610430 537701 rs7928 rs792840363 rs788386582 . . rs790764761 . rs790253409 783643 rs7922 rs792939018 . . rs789303023 rs787799576 rs790042659 rs791523956 rs792708238 rs792708238 020699 rs7896 020699 rs7896 rs791324870 rs789946925 722354 rs7865 rs787056589 rs790623506 rs791095952 rs791585137 rs694781134 rs788801237 . 987172 rs7907 . rs792316973 rs787048313 843482 rs7880 rs789967989 rs793088164 rs787564387 . rs788240629 . 939617 rs7922 rs793540457 . rs792938907 rs790212073 rs786432582 . rs787490616 rs793558438 382912 rs7916 838454 rs7912 327965 rs7906 rs788606098 rs793507808 rs789643509 rs710085081 rs792936491 rs790363249 rs791320565 . rs788410792 rs791896726 rs791290753 317671 rs7912 rs790986375 rs793777266

4 2 3 2 3 2 3 4 2 4 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 3 3 2 2 2 2 2 2 2 2 2 2 2 3 4 2 2 3 2 2 2 2 2 2 4 3 2 2 2 2 4 2 2 4 2 2 3 2 2 2 2 3 4 2 2 2 4 2 2 2 2 2 2 4 2 2 2

AC.GT AC.GT AGGG.CCCT AGGG.CCCT AAAAT.ATTTT AAAAT.ATTTT AG.CT AAAAT.ATTTT AAAC.GTTT AC.GT AAAC.GTTT AAAAC.GTTTT AG.CT AAG.CTT AAG.CTT AC.GT AAAAAC.GTTTTT AC.GT AAAC.GTTT AAAC.GTTT AC.GT AT.AT AAAT.ATTT AC.GT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AC.GT AAC.GTT AG.CT AG.CT AAAAC.GTTTT AC.GT AC.GT AC.GT AAAAC.GTTTT ACACT.AGTGT AAAT.ATTT AAAT.ATTT AAG.CTT AT.AT AG.CT AAAAAC.GTTTTT AG.CT AC.GT AAC.GTT AG.CT AC.GT AAAC.GTTT AG.CT AT.AT ATCC.GGAT AG.CT AG.CT AAC.GTT AGGGC.GCCCT AC.GT AC.GT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AT.AT AT.AT AT.AT AT.AT AT.AT AAT.ATT AAT.ATT AAT.ATT AAT.ATT AAT.ATT AAAC.GTTT AAT.ATT AG.CT AG.CT AAAT.ATTT AAAT.ATTT AT.AT AAC.GTT AAT.ATT AAG.CTT AC.GT

9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9

131710606 131710606 131888400 131888400 131993180 131993180 132269341 132341503 132376655 132655792 132742961 132860030 132950975 133134405 133134405 133171397 133311571 133388792 133493299 133894693 133911722 134030527 134062558 134122745 134321229 134667117 134809426 134826512 134918748 135129001 135157218 135168156 135202849 135301342 135325888 135467507 135590696 135650736 135662500 135727976 135744386 135789979 136644996 136761963 136868007 136876862 136928987 136970300 137390700 137545115 137591967 137665189 137709043 137796877 138086258 138150918 138178014 138433510 138594675 138594675 138594675 138594675 138594675 138598829 138598829 138598829 138598829 138598829 138606455 138606455 138606455 138606455 138606455 138623533 139089627 139139633 139186960 139304512 139379329 139738315 139834025 139964785 139975191 139977728

131710617 131710617 131888413 131888413 131993200 131993200 132269357 132341528 132376692 132655804 132742972 132860049 132950984 133134417 133134417 133171410 133311591 133388801 133493321 133894716 133911733 134030538 134062578 134122757 134321252 134667135 134809440 134826522 134918763 135129014 135157233 135168180 135202885 135301354 135325900 135467524 135590713 135650758 135662522 135727989 135744400 135789990 136645022 136761978 136868017 136876874 136928998 136970312 137390714 137545127 137591978 137665204 137709057 137796887 138086272 138150932 138178024 138433531 138594694 138594694 138594694 138594694 138594694 138598840 138598840 138598840 138598840 138598840 138606471 138606471 138606471 138606471 138606471 138623556 139089638 139139653 139186977 139304534 139379343 139738334 139834041 139964800 139975203 139977741

6 6 3.5 3.5 4.2 4.2 8.5 5.2 9.5 6.5 3 4 5 4.33333 4.33333 7 3.5 5 5.75 6 6 6 5.25 6.5 4.8 4.75 3.75 5.5 5.33333 7 8 5 18.5 6.5 6.5 3.6 3.6 5.75 5.75 4.66667 7.5 6 4.5 8 5.5 4.33333 6 6.5 3.75 6.5 6 4 7.5 5.5 5 3 5.5 11 5 5 5 5 5 6 6 6 6 6 5.66667 5.66667 5.66667 5.66667 5.66667 6 4 10.5 9 5.75 3.75 10 5.66667 5.33333 4.33333 7

ENSSSCT00000016906 RASAL2 intron ENSSSCT00000032575 RASAL2 intron ENSSSCT00000016906 RASAL2 intron ENSSSCT00000032575 RASAL2 intron ENSSSCT00000016906 RASAL2 intron ENSSSCT00000032575 RASAL2 intron ENSSSCT00000026955 RALGPS2 intron ENSSSCT00000016910 . intron ENSSSCT00000016910 . intron ENSSSCT00000016913 TOR3A intron ENSSSCT00000027500 ABL2 intron ENSSSCT00000016916 AXDND1 intron ENSSSCT00000023854 SOAT1 intron ENSSSCT00000016915 TDRD5 intron ENSSSCT00000028228 TDRD5 intron . . intergenic ENSSSCT00000030836 . intron ENSSSCT00000023749 . intron . . intergenic ENSSSCT00000016923 ACBD6 intron ENSSSCT00000016923 ACBD6 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000016926 XPR1 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000016932 CACNA1E intron ENSSSCT00000016932 CACNA1E intron ENSSSCT00000016932 CACNA1E intron ENSSSCT00000016932 CACNA1E intron ENSSSCT00000016932 CACNA1E intron ENSSSCT00000016932 CACNA1E intron ENSSSCT00000016932 CACNA1E intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000016945 LAMC1 intron . . intergenic ENSSSCT00000016947 NMNAT2 intron ENSSSCT00000016947 NMNAT2 intron ENSSSCT00000016947 NMNAT2 intron . . intergenic ENSSSCT00000016953 RGL1 intron ENSSSCT00000030440 COLGALT2 intron ENSSSCT00000030440 COLGALT2 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000016955 C1orf21 intron ENSSSCT00000016955 C1orf21 intron ENSSSCT00000016955 C1orf21 intron . . intergenic ENSSSCT00000035845 FAM129A intron ENSSSCT00000032989 FAM129A intron ENSSSCT00000016958 FAM129A intron ENSSSCT00000036674 FAM129A intron ENSSSCT00000034931 FAM129A intron ENSSSCT00000035845 FAM129A intron ENSSSCT00000032989 FAM129A intron ENSSSCT00000016958 FAM129A intron ENSSSCT00000036674 FAM129A intron ENSSSCT00000034931 FAM129A intron ENSSSCT00000035845 FAM129A intron ENSSSCT00000032989 FAM129A intron ENSSSCT00000016958 FAM129A intron ENSSSCT00000036674 FAM129A intron ENSSSCT00000034931 FAM129A intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000016969 TPR intron ENSSSCT00000016969 TPR intron ENSSSCT00000016969 TPR intron

. . . . 0.293 0.293 . . . -0.296 0.064 0.178 0.248 . . 0.508 0.412 0.259 . 0.103 0.445 . 0.095 . . 0.128 0.034 0.131 0.159 -0.06 0.06 . 0.274 0.004 0.074 -0.199 -0.095 -0.155 0.225 0.181 0.024 -0.016 0.449 0.025 0.013 -0.104 0.06 0.439 . -0.006 0.193 0.045 -0.056 0.074 0.062 0.133 0.036 0.077 0.045 0.045 0.045 0.045 0.045 0.407 0.407 0.407 0.407 0.407 0.346 0.346 0.346 0.346 0.346 . . 0.022 . 0.041 0.091 0.032 0.022 -0.003 -0.128 -0.293

rs792433811 rs792433811 . . rs792281163 rs792281163 rs694828370 . rs787546904 rs793602355 rs788220721 542617 rs7877 . 881760 rs7928 881760 rs7928 . rs788544348 rs790727157 132276 rs7903 528200 rs7927 rs791759072 . rs789011461 . 480824 rs7938 rs791720802 630741 rs7873 rs693101499 rs791230030 rs789282233 rs704600815 rs705395785 rs788260281 rs789862207 969386 rs7937 rs790689267 912195 rs7073 rs789863966 232079 rs7874 rs790799410 rs792866142 rs787274031 rs790902219 . . rs793473525 . rs787185843 436445 rs7915 750203 rs7917 rs786864030 rs787112246 387804 rs7920 rs793692290 rs791442412 . rs790664818 . rs789732288 rs789732288 rs789732288 rs789732288 rs789732288 . . . . . . . . . . rs786768326 . 541030 rs7887 rs791180569 363086 rs7894 rs788526101 . rs792592227 rs791991735 977169 rs7892 .

3 3 2 2 2 2 5 2 2 2 2 2 2 3 3 2 2 2 2 2 4 3 2 3 2 2 2 2 2 2 2 2 3 2 3 2 2 2 2 2 2 3 2 2 5 2 3 3 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2

AT.AT AAAT.ATTT AAAAG.CTTTT AC.GT AAAT.ATTT AAAAC.GTTTT AAT.ATT AAAAAC.GTTTTT AAAC.GTTT AC.GT AAAC.GTTT AT.AT AAAAAT.ATTTTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAG.CTT AAGAG.CTCTT AC.GT AAC.GTT AAC.GTT AAC.GTT AGAGGG.CCCTC AC.GT AAC.GTT AT.AT AAAT.ATTT AG.CT AG.CT AAAC.GTTT AAAAAC.GTTTTT AC.GT AC.GT AG.CT AAC.GTT AAC.GTT AC.GT AAAC.GTTT AAT.ATT AAGG.CCTT AC.GT AC.GT AAAG.CTTT AAAC.GTTT AT.AT AAAC.GTTT AAAC.GTTT AAAG.CTTT AAAAC.GTTTT AAC.GTT AAAC.GTTT AAGG.CCTT AG.CT AATT.AATT AG.CT AC.GT AT.AT AAAT.ATTT AAC.GTT AAC.GTT AAT.ATT AAAAC.GTTTT AACT.AGTT AAGG.CCTT AC.GT AAC.GTT AC.GT AAAT.ATTT AC.GT AC.GT AAAAAC.GTTTTT AG.CT AT.AT AAAC.GTTT AC.GT AC.GT AAAAC.GTTTT AC.GT AT.AT AG.CT AC.GT AC.GT AAAC.GTTT AAAAAT.ATTTTT

9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9

140078471 140136456 140416032 140484248 140487104 140551232 140559997 140642771 140786929 141140559 141140706 141434236 141478335 141497858 141607835 141614355 141626848 141761125 141788155 141869029 142185454 142292276 142539244 143080322 143144279 143327715 143396161 143551153 143551153 143566189 143756750 143776206 143881885 143991835 144008082 144008082 144019920 144074551 144101349 144243921 144300481 144436451 144454541 144479645 144496102 144596844 144723285 144795588 144993132 145018231 145188651 145210878 145313395 145350562 145389748 145456134 145584547 145728870 145820187 145836630 145858452 145982081 146224869 146230832 146287564 146496495 146496901 146743122 146947497 147020795 147076990 147093646 147123143 147132552 147142866 147407154 147428765 147581472 148364489 148412162 148551534 148551534 148858681 148863486

140078483 140136475 140416050 140484257 140487119 140551255 140560010 140642793 140786951 141140585 141140719 141434245 141478356 141497870 141607852 141614377 141626862 141761141 141788175 141869044 142185477 142292294 142539268 143080338 143144293 143327728 143396174 143551165 143551165 143566220 143756772 143776215 143881903 143991849 144008094 144008094 144019935 144074574 144101362 144243935 144300490 144436465 144454552 144479659 144496113 144596858 144723309 144795607 144993146 145018246 145188672 145210893 145313407 145350578 145389758 145456148 145584560 145728884 145820203 145836642 145858466 145982098 146224886 146230857 146287583 146496513 146496913 146743136 146947515 147020807 147077018 147093673 147123154 147132584 147142880 147407163 147428782 147581483 148364499 148412172 148551548 148551548 148858703 148863507

6.5 5 3.8 5 4 4.8 4.66667 3.83333 5.75 13.5 3.5 5 3.66667 3.25 4.5 5.75 5 3.4 10.5 5.33333 8 6.33333 4.16667 8.5 5 7 3.5 6.5 6.5 8 3.83333 5 9.5 7.5 4.33333 4.33333 8 6 4.66667 3.75 5 7.5 3 3.75 6 3.75 6.25 5 3 5.33333 5.5 4 6.5 4.25 5.5 7.5 7 3.75 5.66667 4.33333 5 3.6 4.5 6.5 10 6.33333 6.5 3.75 9.5 6.5 4.83333 14 6 8.25 7.5 5 3.6 6 5.5 5.5 7.5 7.5 5.75 3.66667

. . intergenic . . intergenic . . intergenic ENSSSCT00000022784 PLA2G4A intron ENSSSCT00000022784 PLA2G4A intron ENSSSCT00000022784 PLA2G4A intron ENSSSCT00000022784 PLA2G4A intron . . intergenic . . intergenic ENSSSCT00000031583 KCNK2 intron ENSSSCT00000031583 KCNK2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000016976 SMYD2 intron . . intergenic . . intergenic ENSSSCT00000016978 . promoter . . intergenic ENSSSCT00000016980 . intron ENSSSCT00000016981 ANGEL2 intron ENSSSCT00000016986 NSL1 intron ENSSSCT00000016985 TATDN3 promoter ENSSSCT00000016986 NSL1 intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000016990 NENF promoter ENSSSCT00000024915 NENF promoter ENSSSCT00000016991 TMEM206 intron ENSSSCT00000016992 PPP2R5A intron ENSSSCT00000016992 PPP2R5A intron . . intergenic ENSSSCT00000016993 DTL intron . . intergenic . . intergenic ENSSSCT00000016996 LPGAT1 intron ENSSSCT00000016996 LPGAT1 intron ENSSSCT00000016997 NEK2 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000017001 HHAT intron ENSSSCT00000017001 HHAT intron ENSSSCT00000017001 HHAT intron . . intergenic . . intergenic . . intergenic ENSSSCT00000017004 SYT14 intron ENSSSCT00000017004 SYT14 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000020629 sc-mir-29b- promoter ENSSSCT00000021258 ssc-mir-29c promoter ENSSSCT00000031404 ABCA13 intron ENSSSCT00000031404 ABCA13 intron

. . -0.029 . -0.082 -0.342 0.003 -0.178 . -0.015 -0.024 . -0.12 0.159 -0.098 . -0.016 0.033 -0.022 -0.075 -0.14 -0.008 . 0.385 0.445 0.401 1.513 0.163 0.163 0.275 -0.182 . -0.012 -0.07 -0.033 -0.033 0.443 0.254 . -0.072 0.732 0.129 0.047 . 0.315 -0.097 0.138 0.184 0.21 0.042 . 0.082 0.248 . -0.355 0.066 -0.322 . . . 1.179 . 0.057 0.102 . 0.04 0.014 -0.011 0.023 . -0.058 . . -0.075 -0.022 . . -0.072 -0.218 . 0.01 0.01 . -0.318

rs792594960 rs791443033 942485 rs7907 rs789244680 rs788301503 rs786208974 rs792570717 . rs787325721 rs705423429 rs787446109 rs786589715 rs788929234 . rs793537795 116220 rs7898 . . rs790578766 rs791060592 709583 rs7900 rs787171927 rs791639471 . rs787383243 rs792811327 rs786882826 . . 979706 rs7925 rs788744350 rs786796886 . 392084 rs7901 rs791697404 rs791697404 rs786631961 094943 rs7889 rs793203983 rs792749633 rs793467476 rs791491585 . 235677 rs7877 112013 rs7912 037492 rs7905 rs791698863 rs792512992 386668 rs7885 943808 rs7871 rs791276127 067600 rs7937 800509 rs7920 029704 rs7912 . 539024 rs7910 rs789032404 017791 rs7935 rs788209539 rs789585165 rs793383000 rs791800001 014875 rs7918 rs788503885 rs792309976 rs786521685 rs791432331 . 722556 rs7890 rs792578160 511048 rs7878 . 896089 rs7885 673832 rs7893 rs787458208 rs791367130 448635 rs7893 719520 rs7906 rs792443462 rs787523203 . . rs793245285 .

4 2 2 3 2 2 2 2 3 5 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 3 2 2 2 2 2 2 2 4 2 2 2 3 6 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 3 4 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2

AC.GT AT.AT AAAAC.GTTTT AG.CT AAC.GTT AT.AT AT.AT AAC.GTT AAAC.GTTT AAAT.ATTT AC.GT AC.GT AC.GT ATAT.ATAT AAAC.GTTT AC.GT AT.AT AAAG.CTTT AC.GT AG.CT AC.GT AAAC.GTTT AC.GT AAAC.GTTT AC.GT AAAAG.CTTTT AAAC.GTTT AG.CT AAT.ATT AT.AT AAAC.GTTT AC.GT AC.GT AG.CT AC.GT AC.GT AC.GT AAAC.GTTT AAG.CTT AAAAT.ATTTT AAT.ATT ACCT.AGGT AAAGG.CCTTT AT.AT AAAT.ATTT AAAG.CTTT AC.GT AG.CT AC.GT AAAC.GTTT AT.AT AACCC.GGGTT AT.AT AAC.GTT AAAAAC.GTTTTT AAAC.GTTT AT.AT AC.GT AAAT.ATTT AC.GT AACC.GGTT AC.GT AC.GT AT.AT AT.AT AAAT.ATTT AAC.GTT AAAC.GTTT AC.GT AG.CT AC.GT AC.GT AT.AT AC.GT AC.GT AG.CT AG.CT ACAG.CTGT ACAG.CTGT AAAC.GTTT AC.GT AAAT.ATTT AAAAC.GTTTT AAAC.GTTT

9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X

148897728 148900571 148967931 148992024 149022438 149062857 149216873 149313360 149480497 149879385 150286532 150286532 150766463 151014667 151367447 151418328 151428155 151699754 151756977 151886869 151914967 151926566 152161133 152161969 152235226 152281102 152429412 152434883 152561961 152614199 152834598 152990072 152997985 153063490 444037 819613 1129513 1289334 1467641 1522406 1541856 1639259 1685405 1704171 1876058 2210963 2257515 2351534 2362792 2736242 2796922 2802844 2826775 2912015 3058293 3164803 3386575 3463312 3512867 3747742 4116492 4202205 4202205 4231696 4231696 4445274 4447363 4487649 4704811 4770462 4929889 4929889 5244346 5470234 5470234 5534751 5534751 5552046 5552046 5624170 5716801 5839225 5868146 5873883

148897738 148900580 148967954 148992050 149022454 149062866 149216884 149313371 149480516 149879402 150286541 150286541 150766473 151014697 151367467 151418344 151428166 151699768 151756992 151886878 151914978 151926583 152161157 152161984 152235238 152281123 152429426 152434906 152561986 152614210 152834616 152990084 152997997 153063505 444070 819625 1129525 1289350 1467652 1522424 1541879 1639281 1685428 1704180 1876086 2210983 2257525 2351546 2362801 2736269 2796942 2802859 2826784 2912027 3058315 3164821 3386585 3463326 3512881 3747752 4116506 4202219 4202219 4231705 4231705 4445288 4447385 4487664 4704822 4770478 4929900 4929900 5244361 5470248 5470248 5534762 5534762 5552061 5552061 5624191 5716815 5839247 5868174 5873905

5.5 5 4.8 13.5 5.66667 5 6 4 5 4.5 5 5 5.5 7.75 5.25 8.5 6 3.75 8 5 6 4.5 12.5 4 6.5 4.4 3.75 12 8.66667 6 4.75 6.5 6.5 8 17 6.5 6.5 4.25 4 3.8 8 5.75 4.8 5 7.25 5.25 5.5 6.5 5 7 10.5 3.2 5 4.33333 3.83333 4.75 5.5 7.5 3.75 5.5 3.75 7.5 7.5 5 5 3.75 7.66667 4 6 8.5 6 6 8 7.5 7.5 6 6 4 4 5.5 7.5 5.75 5.8 5.75

ENSSSCT00000031404 ABCA13 intron ENSSSCT00000031404 ABCA13 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000031836 GRB10 intron ENSSSCT00000017025 GRB10 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000013231 NLGN4X intron ENSSSCT00000013231 NLGN4X intron ENSSSCT00000013231 NLGN4X intron ENSSSCT00000013231 NLGN4X intron ENSSSCT00000013231 NLGN4X intron ENSSSCT00000013231 NLGN4X intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000032160 STS intron ENSSSCT00000035627 STS intron ENSSSCT00000032160 STS intron ENSSSCT00000035627 STS intron ENSSSCT00000032160 STS intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000034295H242-236E1 intron ENSSSCT00000035815H242-236E1 intron ENSSSCT00000035815H242-236E1 intron ENSSSCT00000035619 KAL1 intron ENSSSCT00000013235 KAL1 intron ENSSSCT00000035619 KAL1 intron ENSSSCT00000013235 KAL1 intron ENSSSCT00000035619 KAL1 intron ENSSSCT00000013235 KAL1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

-0.303 0.419 0.035 -0.305 -0.244 0.022 . . . . -0.026 -0.026 . . . -0.178 -0.283 -0.295 . -0.144 . -0.113 . . . -0.066 . -0.307 -0.434 . -0.057 0.183 0.108 . -0.46 -0.066 . -0.169 . . -0.421 . -0.534 . . 0.09 -0.002 . . . -0.292 . -0.282 . . . -0.113 . . 0.07 . . . . . . -0.291 -0.526 -0.256 -0.214 -0.111 -0.111 0.084 0.052 0.052 . . -0.256 -0.256 -0.117 -0.018 . 0.065 0.095

rs787117636 rs788650583 rs792411458 rs786535082 rs788033088 . . rs789046986 rs787686379 rs788095348 rs791775782 rs791775782 rs786567765 624701 rs7884 . rs788934233 814226 rs7872 892608 rs7881 . 793196 rs7064 323057 rs7015 rs788495217 rs786980826 . . 208330 rs7937 098566 rs7906 084027 rs7936 rs789942763 . rs789968655 533918 rs7896 rs793708017 rs789055778 329075 rs7914 108129 rs7917 rs789524002 041192 rs7936 rs787427320 rs787500245 rs793083766 rs786272548 rs786842340 rs709120291 rs790687663 rs791672665 rs786587327 rs786812803 rs790758536 . rs788940848 rs790303695 rs786925596 rs791744762 rs790392878 rs791208215 rs703409209 rs790478183 727427 rs7896 . rs792136715 rs786933849 rs786933849 066110 rs7898 066110 rs7898 rs789908377 rs788770945 340671 rs7933 rs789499434 rs709407472 rs789409316 rs789409316 090917 rs6974 rs792609471 rs792609471 436011 rs7882 436011 rs7882 rs791173408 rs791173408 rs786376842 . rs789577959 813969 rs7922 584605 rs7921

2 2 2 2 3 2 3 2 2 2 2 2 2 4 2 3 2 2 2 3 2 2 2 3 2 2 4 2 2 2 2 2 2 2 4 2 3 2 3 2 2 2 3 2 2 2 2 2 2 2 2 2 3 2 2 2 3 7 2 3 2 2 2 2 2 2 2 2 2 2 3 3 4 3 3 2 2 2 2 2 2 4 2 2

AC.GT AC.GT AC.GT AC.GT AAC.GTT AAC.GTT AAAC.GTTT ACAT.ATGT AAG.CTT AAG.CTT AAAAT.ATTTT AT.AT AC.GT AAC.GTT AAAG.CTTT AAAC.GTTT AG.CT AAC.GTT AT.AT AAAAC.GTTTT AAAAAC.GTTTTT AAT.ATT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AG.CT AT.AT AAAAAC.GTTTTT AAAC.GTTT AG.CT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAT.ATTT AAAAT.ATTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AC.GT AC.GT AC.GT AC.GT AAAAG.CTTTT AC.GT AAG.CTT AG.CT AG.CT AG.CT AG.CT AG.CT AC.GT AATG.CATT AATG.CATT AAAAAC.GTTTTT AAT.ATT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAG.CTT AAG.CTT AAG.CTT AC.GT AAAT.ATTT AAAT.ATTT ACC.GGT ACC.GGT AT.AT AC.GT AAAC.GTTT AAAC.GTTT AG.CT AG.CT AC.GT AT.AT AAAC.GTTT AAAAG.CTTTT AAAAG.CTTTT AT.AT

X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X

6413272 7054349 7351388 7351388 7413661 7413661 8312285 8434275 8473400 8473400 8867390 8882856 9272068 9470380 9996528 10064586 10158556 10219237 10331375 10538650 10718558 10998450 11168688 11609926 11609926 11635521 11715821 11803988 11826470 11888005 12069720 12154582 12154582 12294886 12332588 12369150 12369150 12369150 13009154 13009154 13009154 13067229 13067229 13067229 13088154 13705813 13847579 14019281 14391053 14391053 14391053 14391053 14765960 14873910 15225740 15225740 15438238 16000228 16231586 16231586 16231586 16350441 16350441 16350441 16400734 16400734 16400734 16692006 17038275 17038275 17100361 17100361 17911140 17962087 19408511 19408511 19546508 19546508 20130106 20447048 20769242 20891858 20891858 20915904

6413283 7054359 7351402 7351402 7413676 7413676 8312312 8434291 8473411 8473411 8867409 8882867 9272080 9470396 9996544 10064600 10158577 10219259 10331392 10538668 10718581 10998469 11168717 11609949 11609949 11635533 11715831 11804013 11826489 11888015 12069740 12154594 12154594 12294905 12332610 12369165 12369165 12369165 13009174 13009174 13009174 13067239 13067239 13067239 13088169 13705833 13847598 14019294 14391067 14391067 14391067 14391067 14765971 14873929 15225764 15225764 15438260 16000258 16231606 16231606 16231606 16350459 16350459 16350459 16400750 16400750 16400750 16692016 17038292 17038292 17100380 17100380 17911149 17962099 19408531 19408531 19546519 19546519 20130120 20447068 20769263 20891881 20891881 20915915

6 5.5 7.5 7.5 5.33333 5.33333 7 4.25 4 4 4 6 6.5 5.66667 4.25 3.75 11 7.66667 9 3.8 4 6.66667 6 6 6 6.5 5.5 4.33333 5 5.5 5.25 3.25 3.25 5 4.6 4 4 4 5.25 5.25 5.25 5.5 5.5 5.5 8 4.2 10 4.66667 7.5 7.5 7.5 7.5 6 10 6.25 6.25 3.83333 10.3333 5.25 5.25 5.25 4.75 4.75 4.75 5.66667 5.66667 5.66667 5.5 4.5 4.5 6.66667 6.66667 5 6.5 5.25 5.25 6 6 7.5 10.5 5.5 4.8 4.8 6

. . ENSSSCT00000033365 ENSSSCT00000035935 ENSSSCT00000022263 ENSSSCT00000035935 . . ENSSSCT00000035835 ENSSSCT00000013247 ENSSSCT00000033647 ENSSSCT00000033647 . . . . . . ENSSSCT00000034697 . . ENSSSCT00000035913 ENSSSCT00000035913 ENSSSCT00000013266 ENSSSCT00000033507 . . . . . . ENSSSCT00000033189 ENSSSCT00000013268 . . ENSSSCT00000036081 ENSSSCT00000013270 ENSSSCT00000033995 ENSSSCT00000032788 ENSSSCT00000013276 ENSSSCT00000032899 ENSSSCT00000013277 ENSSSCT00000034032 ENSSSCT00000034745 ENSSSCT00000013277 . . ENSSSCT00000013285 ENSSSCT00000033396 ENSSSCT00000026314 ENSSSCT00000034223 ENSSSCT00000013289 . . ENSSSCT00000033095 ENSSSCT00000032786 . . ENSSSCT00000032659 ENSSSCT00000033642 ENSSSCT00000013297 ENSSSCT00000032792 ENSSSCT00000035020 ENSSSCT00000034554 ENSSSCT00000031758 ENSSSCT00000035020 ENSSSCT00000034554 . ENSSSCT00000036543 ENSSSCT00000024706 ENSSSCT00000036543 ENSSSCT00000024706 . . ENSSSCT00000034419 ENSSSCT00000013308 ENSSSCT00000034419 ENSSSCT00000013308 . . . ENSSSCT00000034582 ENSSSCT00000013312 .

. . CLCN4 CLCN4 CLCN4 CLCN4 . . ARHGAP6 ARHGAP6 ARHGAP6 ARHGAP6 . . . . . . FRMPD4 . . EGFL6 EGFL6 GEMIN8 GEMIN8 . . . . . . GLRA2 GLRA2 . . MOSPD2 MOSPD2 MOSPD2 BMX BMX BMX ACE2 ACE2 ACE2 ACE2 . . CTPS2 REPS2 REPS2 REPS2 REPS2 . . NHS NHS . . CDKL5 CDKL5 CDKL5 PPEF1 PPEF1 PPEF1 PPEF1 PPEF1 PPEF1 . MAP3K15 MAP3K15 MAP3K15 MAP3K15 . . PHEX PHEX PHEX PHEX . . . PTCHD1 PTCHD1 .

intergenic intergenic intron intron intron intron intergenic intergenic 3'utr 3'utr intron intron intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intron intron intron intron intron promoter intron intron promoter intron intergenic intergenic intron intron intron intron intron intergenic intergenic intron intron intergenic intergenic intron intron intron intron intron intron intron intron intron intergenic intron intron intron intron intergenic intergenic intron intron intron intron intergenic intergenic intergenic intron intron intergenic

-0.135 . -0.058 -0.058 -0.229 -0.229 0.07 . 1.552 1.552 . 0.19 . 0.243 -0.349 0.174 . 0.086 0.076 0.094 -0.021 0.117 0.129 0.199 0.199 0.486 -0.021 0.4 0.421 0.14 . 0.134 0.134 0.236 . 0.317 0.317 0.317 0.152 0.152 0.152 0.13 0.13 0.13 . 0.369 . 0.21 . . . . 0.503 0.269 0.195 0.195 . . 0.358 0.358 0.358 0.39 0.39 0.39 0.31 0.31 0.31 . . . 0.548 0.548 . 0.324 0.23 0.23 0.17 0.17 . -0.031 0.228 0.517 0.517 1.015

rs786732548 rs787964763 rs791752577 rs791752577 rs787765686 rs787765686 rs789020935 . rs791195052 rs791195052 rs786820460 . rs786647653 643119 rs7865 rs786301018 rs793795236 732419 rs7922 rs789657942 rs791476539 rs789328627 rs786546504 rs791838738 rs788768559 890522 rs7893 890522 rs7893 rs788300475 rs793590804 974458 rs7935 rs786596315 . rs786507618 rs788252665 rs788252665 646600 rs7888 195322 rs7893 963822 rs7909 963822 rs7909 963822 rs7909 rs787247646 rs787247646 rs787247646 rs788810847 rs788810847 rs788810847 rs792419619 rs788335952 rs789287321 rs790732654 . . . . rs793769259 rs792226537 rs788102735 rs788102735 rs791443818 rs791824693 rs792529452 rs792529452 rs792529452 rs791763448 rs791763448 rs791763448 rs792324460 rs792324460 rs792324460 . rs790081070 rs790081070 rs793334333 rs793334333 rs793560852 . rs793838836 rs793838836 rs787540011 rs787540011 847187 rs7909 rs792383454 rs789589154 rs791382418 rs791382418 rs789568474

2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 4 4 4 4 2 5 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2

AG.CT AAAC.GTTT AAT.ATT AAAG.CTTT AAACC.GGTTT AAAT.ATTT AAAT.ATTT AC.GT AAAC.GTTT AAAG.CTTT AAAT.ATTT AAATT.AATTT AAAAC.GTTTT AAT.ATT AAT.ATT AAAAG.CTTTT AAAT.ATTT AT.AT AAAAC.GTTTT AG.CT AC.GT AT.AT AT.AT AAAC.GTTT AATATG.CATATT AC.GT AAAC.GTTT AAAC.GTTT AC.GT AC.GT AAAT.ATTT AAC.GTT AATC.GATT AT.AT AC.GT AC.GT ACAT.ATGT AATG.CATT AAAT.ATTT AAATAC.GTATTT AG.CT AAAC.GTTT AC.GT AC.GT AAAT.ATTT AC.GT AC.GT AC.GT AC.GT AC.GT AAAC.GTTT AC.GT AAAT.ATTT AAAAAC.GTTTTT AAAC.GTTT AAAC.GTTT AG.CT AG.CT AT.AT AT.AT AAAC.GTTT AAAC.GTTT AT.AT AT.AT AAAC.GTTT AAAC.GTTT AC.GT AAT.ATT AAT.ATT AC.GT AT.AT ACAT.ATGT AC.GT AAAC.GTTT AAAT.ATTT AAT.ATT AAC.GTT AT.AT AG.CT AAAC.GTTT AC.GT AC.GT AC.GT AC.GT

X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X

21157234 22331548 22351133 22395699 22426208 22488261 22539939 22677879 22811269 22895788 23009506 23234475 23299237 23303109 23401877 23822154 24305338 24487702 24563571 24571632 24664275 24768644 25151129 25269977 25592448 26001291 26148597 26221486 26295726 26300140 26319267 26726654 26754543 26831808 26957814 27672549 27677955 27874529 27932768 27962946 27969973 27980554 28193683 28668684 28931920 28938922 29484329 29484329 29505452 29505452 29594018 29683392 29783843 31002914 31322893 31322893 31362918 31362918 31764118 31764118 31809224 31809224 31825580 31825580 31875864 31875864 32057928 32321319 32686731 34092317 34146088 34582621 34748953 34973092 34980131 35210614 35563234 35639983 35701844 35821033 35833975 36411268 36842334 36842334

21157250 22331574 22351144 22395718 22426235 22488279 22539966 22677889 22811283 22895812 23009518 23234500 23299255 23303135 23401890 23822184 24305355 24487712 24563589 24571643 24664284 24768661 25151156 25270002 25592469 26001303 26148612 26221506 26295750 26300150 26319287 26726680 26754570 26831826 26957829 27672570 27677970 27874557 27932792 27962966 27969983 27980568 28193705 28668694 28931935 28938932 29484340 29484340 29505462 29505462 29594053 29683413 29783862 31002943 31322904 31322904 31362929 31362929 31764127 31764127 31809267 31809267 31825589 31825589 31875888 31875888 32057968 32321336 32686744 34092346 34146098 34582646 34748977 34973119 34980151 35210635 35563251 35639995 35701858 35821047 35833990 36411299 36842345 36842345

8.5 6.75 4 5 5.6 4.75 7 5.5 3.75 6.25 3.25 5.2 3.8 9 4.66667 6.2 4.5 5.5 3.8 6 5 9 14 6.5 3.66667 6.5 4 5.25 12.5 5.5 5.25 9 7 9.5 8 11 4 7.25 6.25 3.5 5.5 3.75 11.5 5.5 4 5.5 6 6 5.5 5.5 9 11 5 5 3 3 6 6 5 5 11 11 5 5 6.25 6.25 20.5 6 4.66667 15 5.5 6.5 12.5 7 5.25 7.33333 6 6.5 7.5 3.75 8 16 6 6

. . . ENSSSCT00000033790 ENSSSCT00000033790 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000026433 . . . ENSSSCT00000029079 ENSSSCT00000013350 ENSSSCT00000029079 ENSSSCT00000013350 . . . . ENSSSCT00000034304 ENSSSCT00000026041 ENSSSCT00000034304 ENSSSCT00000026041 ENSSSCT00000034304 ENSSSCT00000026041 ENSSSCT00000026041 ENSSSCT00000034304 ENSSSCT00000026041 ENSSSCT00000034304 ENSSSCT00000034304 ENSSSCT00000026041 . . . . . . . . . . . ENSSSCT00000034859 ENSSSCT00000023277 . . . ENSSSCT00000028670 ENSSSCT00000036005

. . . POLA1 POLA1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . DMD DMD DMD DMD . . . . DMD DMD DMD DMD DMD DMD DMD DMD DMD DMD DMD DMD . . . . . . . . . . . CXorf30 CXorf30 . . . PRRG1 PRRG1

intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic exon intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intron intron intron intron intron intron intron intron intron intron intron promoter intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intron intron

-0.23 0.596 0.2 0.518 0.438 . . . 0.32 0.202 . 0.234 . 0.165 0.265 . 0.145 0.53 0.137 0.225 . . 0.247 . 0.256 . 0.298 . 0.267 0.386 0.599 0.021 . 0.206 -0.045 -0.054 0.024 0.196 0.012 0.501 0.03 0.473 0.729 . . . -0.027 -0.027 . . 0.092 0.264 0.389 0.107 0.016 0.016 -0.183 -0.183 0.067 0.067 . . 0.089 0.089 0.773 0.773 0.127 0.074 . 0.131 . 0.319 . . 0.072 . . 0.258 . . 0.055 0.144 . .

rs789902622 rs788801306 rs789490613 rs786684734 . . rs793757045 . rs793339842 rs790168826 rs791935652 rs788739561 . rs788784682 rs791622522 rs793482822 rs787083544 rs789895739 rs790636137 . . rs788583599 058160 rs7937 rs792342108 rs791283087 rs792970151 rs791909843 rs791306507 054083 rs7869 . 281781 rs7874 rs792264873 rs790036968 rs789252749 . rs788284359 rs787777193 rs789921955 rs788999321 rs788096655 rs791206836 rs792488458 . . rs786311944 . rs786867395 rs786867395 rs786592457 rs786592457 . . rs792058914 rs793277652 . . . . rs790032476 rs790032476 rs786660655 rs786660655 rs792469622 rs792469622 . . 461238 rs7933 rs790635253 rs787979627 rs790831853 . rs787650765 . rs793339151 . rs788500941 334297 rs7876 402498 rs7862 . rs790780328 . rs786376478 307532 rs7916 307532 rs7916

2 4 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 3 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 3 3 2 2 2 2 2 2 2 2 3 2 2 3 2 3 4 3 2 2 2 3 2 2 3 3 3 3

AC.GT AC.GT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AT.AT AGC.GCT AAAC.GTTT AAAT.ATTT ACG.CGT ACG.CGT ACG.CGT AG.CT AT.AT AT.AT AT.AT AT.AT AAC.GTT AAAC.GTTT AAG.CTT AG.CT AAAAC.GTTTT AAAC.GTTT AAAC.GTTT AC.GT AAC.GTT AAT.ATT AT.AT AC.GT AC.GT AC.GT AC.GT AAAG.CTTT AAAG.CTTT AAAG.CTTT AAAC.GTTT AT.AT AT.AT AATT.AATT AATT.AATT AATT.AATT AATT.AATT AATT.AATT AATT.AATT AATT.AATT AATT.AATT AATT.AATT AATT.AATT AAC.GTT AC.GT AC.GT AT.AT AAAT.ATTT AAAG.CTTT AG.CT AAAAC.GTTTT AC.GT AAAC.GTTT AAAC.GTTT AC.GT AAAC.GTTT AAAC.GTTT AAAT.ATTT AC.GT AAAC.GTTT AC.GT AAAAT.ATTTT AAT.ATT AAAAT.ATTTT AG.CT AAAAAC.GTTTTT AAAAAC.GTTTTT AAAAG.CTTTT AAC.GTT AT.AT AT.AT AG.CT AATG.CATT AT.AT AAT.ATT AAG.CTT AC.GT AG.CT

X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X

37274150 37882455 37905681 37905681 37905681 37905681 38273741 38280232 39415385 39541295 39904595 39904595 39904595 40059612 40362325 40433357 40433357 40433357 40662973 41061754 41097333 41263607 41267907 41628962 41628962 42212688 42339329 42672018 42817787 43105036 43180788 43180788 43180788 43182887 43182887 43182887 43688332 43794506 43794506 44651634 44651634 44651634 44651634 44651634 44651634 44651634 44651634 44651634 44651634 44822239 44958444 45156176 45168144 45272186 45342534 45393260 45542374 46315059 46427287 46427287 47111007 47345819 47345819 48214404 48460740 48517075 48537959 48624892 48740717 48799129 48801987 48889720 48889720 48920252 48957362 48994774 49054855 49127104 49214980 49353169 49597802 49653988 50006282 50389150

37274159 37882470 37905692 37905692 37905692 37905692 38273750 38280245 39415399 39541309 39904611 39904611 39904611 40059625 40362336 40433367 40433367 40433367 40662998 41061766 41097348 41263620 41267924 41628981 41628981 42212698 42339340 42672038 42817800 43105049 43180801 43180801 43180801 43182900 43182900 43182900 43688354 43794517 43794517 44651651 44651651 44651651 44651651 44651651 44651651 44651651 44651651 44651651 44651651 44822250 44958456 45156194 45168154 45272208 45342548 45393270 45542392 46315069 46427314 46427314 47111016 47345834 47345834 48214418 48460756 48517098 48537971 48624910 48740737 48799145 48802000 48889743 48889743 48920270 48957375 48994786 49054874 49127128 49215000 49353198 49597820 49654003 50006294 50389170

5 8 4 4 4 4 5 4.66667 3.75 3.75 5.66667 5.66667 5.66667 7 6 5.5 5.5 5.5 8.66667 3.25 5.33333 7 3.6 5 5 5.5 4 7 7 7 7 7 7 3.5 3.5 3.5 5.75 6 6 4.5 4.5 4.5 4.5 4.5 4.5 4.5 4.5 4.5 4.5 4 6.5 9.5 5.5 5.75 3.75 5.5 3.8 5.5 7 7 5 4 4 3.75 8.5 6 6.5 3.8 7 3.4 7 4 4 3.8 4.66667 6.5 10 12.5 5.25 15 6.33333 5.33333 6.5 10.5

. . intergenic . . intergenic ENSSSCT00000034622 SRPX intron ENSSSCT00000013380 SRPX intron ENSSSCT00000036512 SRPX intron ENSSSCT00000034428 SRPX intron . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000035677 BCOR intron ENSSSCT00000034818 BCOR intron ENSSSCT00000035361 BCOR intron . . intergenic . . intergenic ENSSSCT00000013395 CXorf38 intron ENSSSCT00000035325 CXorf38 intron ENSSSCT00000036189 CXorf38 intron . . intergenic ENSSSCT00000033052 H242-15C8 exon . . intergenic . . intergenic . . intergenic ENSSSCT00000035253 CASK intron ENSSSCT00000013399 CASK intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000033354 MAOA intron ENSSSCT00000013404 MAOA intron ENSSSCT00000032764 MAOA intron ENSSSCT00000033354 MAOA intron ENSSSCT00000013404 MAOA intron ENSSSCT00000032764 MAOA intron . . intergenic ENSSSCT00000029739 EFHC2 intron ENSSSCT00000035249 EFHC2 intron ENSSSCT00000034832 KDM6A intron ENSSSCT00000034861 KDM6A intron ENSSSCT00000035071 KDM6A intron ENSSSCT00000035936 KDM6A intron ENSSSCT00000013409 KDM6A intron ENSSSCT00000034919 KDM6A intron ENSSSCT00000033770 KDM6A intron ENSSSCT00000033265 KDM6A intron ENSSSCT00000035863 KDM6A intron ENSSSCT00000036305 KDM6A intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000013414 JADE3 intron ENSSSCT00000033102 JADE3 intron . . intergenic ENSSSCT00000033024 SYN1 intron ENSSSCT00000013425 SYN1 intron ENSSSCT00000029010 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000013457 CCNB3 intron ENSSSCT00000035730 CCNB3 intron . . intergenic ENSSSCT00000013458 . intron ENSSSCT00000013458 . intron ENSSSCT00000013458 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

-0.037 0.123 . . . . 0.361 0.236 -0.134 0.544 0.146 0.146 0.146 0.021 0.252 -0.156 -0.156 -0.156 . 1.399 . 0.177 -0.115 0.235 0.235 0.134 0.217 0.284 0.25 0.112 0.306 0.306 0.306 . . . 0.166 . . 0.305 0.305 0.305 0.305 0.305 0.305 0.305 0.305 0.305 0.305 . 0.19 0.202 -0.028 0.071 0.458 0.281 . 0.357 . . . 0.182 0.182 -0.672 0.207 . . 0.385 0.165 0.16 0.184 . . . . . 0.978 0.134 0.183 0.239 0.161 . 0.296 .

. . rs792105344 rs792105344 rs792105344 rs792105344 964543 rs7917 . rs788832010 rs788877296 rs790956970 rs790956970 rs790956970 . rs791381713 . . . rs790460649 839780 rs7869 rs789109384 rs793312528 rs790424528 rs789268222 rs789268222 rs793542398 rs788173813 rs788902643 476322 rs7866 rs787821952 rs789525502 rs789525502 rs789525502 rs788131584 rs788131584 rs788131584 rs787330094 rs790624497 rs790624497 rs791262832 rs791262832 rs791262832 rs791262832 rs791262832 rs791262832 rs791262832 rs791262832 rs791262832 rs791262832 . 614497 rs7930 rs792973283 . rs793305311 rs790881103 rs787783842 204260 rs7871 rs792373853 129070 rs7921 129070 rs7921 383659 rs7937 rs793225989 rs793225989 rs791215178 rs792956381 rs792616012 rs787260020 rs789937779 rs786988680 rs792340013 rs786224782 rs786973839 rs786973839 rs788661283 rs786784976 282497 rs7872 rs788960456 305087 rs7921 rs790786205 rs791524335 rs792412282 rs789461783 rs786760175 rs788426983

2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 3 3 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 4 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 3 4 2 2 2 2 3 2

AAAAT.ATTTT AT.AT AT.AT AAAAC.GTTTT AT.AT ACC.GGT AT.AT AT.AT AAAC.GTTT AC.GT AC.GT AAAAT.ATTTT AAAAT.ATTTT AAAAT.ATTTT AAAAT.ATTTT AAAAT.ATTTT AAAAT.ATTTT AAAAT.ATTTT AAC.GTT AAC.GTT AAC.GTT AAC.GTT ACC.GGT AC.GT AC.GT AG.CT AT.AT AC.GT AAAT.ATTT AG.CT AAAAC.GTTTT AAC.GTT AAAC.GTTT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AG.CT AAT.ATT AT.AT AG.CT AC.GT AC.GT AT.AT AG.CT AC.GT AAAAAT.ATTTTT AC.GT AC.GT AAGG.CCTT AG.CT AAAT.ATTT AAAT.ATTT AAAAT.ATTTT AT.AT AAC.GTT AAG.CTT AG.CT AAT.ATT AAAC.GTTT ACC.GGT AG.CT AAAC.GTTT AG.CT AAAC.GTTT AG.CT AATG.CATT AATG.CATT AG.CT AT.AT AC.GT AAAC.GTTT AAAAC.GTTTT AC.GT AAAG.CTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT ATC.GAT AAC.GTT AAC.GTT

X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X

50515676 50550137 50555730 50709174 50723851 50894362 50980195 51001066 51218405 51340559 51390452 51703606 51703606 51703606 51703606 51703606 51703606 51703606 51885038 51885038 51885038 51885038 51992675 52896611 52896611 52981915 53110969 53243802 54077231 55283934 55912666 56012734 56160831 56270907 56617365 56617365 56617365 56617365 56617365 56825471 56852785 57006481 57183539 57683687 57989487 58180293 58198170 58409470 58441694 58455381 58486018 58743506 58783062 58893252 58893252 59060033 59113771 59412727 60399370 60630427 60931187 61376249 61431865 61446124 62094883 62436155 62470960 62614845 63127059 63127059 63485430 63682597 63686551 64462753 64484995 64629900 64836696 64955365 64982299 64982299 64982299 65020663 65025130 65025130

50515697 50550152 50555739 50709203 50723869 50894375 50980210 51001075 51218431 51340574 51390465 51703637 51703637 51703637 51703637 51703637 51703637 51703637 51885060 51885060 51885060 51885060 51992686 52896626 52896626 52981933 53110980 53243816 54077251 55283948 55912687 56012753 56160853 56270934 56617387 56617387 56617387 56617387 56617387 56825511 56852802 57006494 57183551 57683705 57989499 58180321 58198184 58409483 58441715 58455403 58486051 58743524 58783075 58893263 58893263 59060052 59113783 59412743 60399384 60630443 60931200 61376264 61431878 61446135 62094902 62436184 62470996 62614855 63127076 63127076 63485444 63682608 63686564 64462772 64485014 64629910 64836709 64955386 64982317 64982317 64982317 65020681 65025142 65025142

4.4 8 5 6 9.5 4.66667 8 5 6.75 8 7 6.4 6.4 6.4 6.4 6.4 6.4 6.4 7.66667 7.66667 7.66667 7.66667 4 8 8 9.5 6 7.5 5.25 7.5 4.4 6.66667 5.75 9.33333 7.66667 7.66667 7.66667 7.66667 7.66667 20.5 6 7 6.5 9.5 6.5 14.5 7.5 7 3.66667 11.5 17 4.75 7 3 3 4 6.5 5.66667 5 8.5 4.66667 4 4.66667 6 5 15 9.25 5.5 4.5 4.5 7.5 6 7 5 4 5.5 3.5 5.5 4.75 4.75 4.75 6.33333 4.33333 4.33333

. . . . . . . . . . ENSSSCT00000033938 ENSSSCT00000034912 ENSSSCT00000033805 ENSSSCT00000033717 ENSSSCT00000033262 ENSSSCT00000035966 ENSSSCT00000028659 ENSSSCT00000013478 ENSSSCT00000034630 ENSSSCT00000035055 ENSSSCT00000013481 ENSSSCT00000032330 . ENSSSCT00000013486 ENSSSCT00000034044 . . . . . . . . . ENSSSCT00000033812 ENSSSCT00000033580 ENSSSCT00000013519 ENSSSCT00000033226 ENSSSCT00000035007 . . . . ENSSSCT00000032193 . ENSSSCT00000013524 ENSSSCT00000013524 . . . ENSSSCT00000034603 . . ENSSSCT00000013520 ENSSSCT00000034250 . . . ENSSSCT00000013528 . . . . . . . . . ENSSSCT00000034708 ENSSSCT00000033545 . ENSSSCT00000013532 ENSSSCT00000013532 . . . . . ENSSSCT00000013561 ENSSSCT00000035659 ENSSSCT00000032783 ENSSSCT00000034006 ENSSSCT00000034006 ENSSSCT00000013559

. . . . . . . . . . GPR173 SMC1A RIBC1 . . . . . HUWE1 HUWE1 HUWE1 HUWE1 . WNK3 WNK3 . . . . . . . . . ARHGEF9 ARHGEF9 ARHGEF9 ARHGEF9 ARHGEF9 . . . . ZC4H2 . ZC3H12B ZC3H12B . . . MSN . . HEPH HEPH . . . AR . . . . . . . . . EDA EDA . DLG3 DLG3 . . . . . OGT OGT OGT ACRC ACRC ACRC

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron promoter promoter promoter promoter promoter intron intron intron intron intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intergenic intergenic intergenic intergenic intron intergenic intron intron intergenic intergenic intergenic intron intergenic intergenic promoter promoter intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intron intron intergenic intergenic intergenic intergenic intergenic intron intron intron promoter intron promoter

. . 0.094 0.176 . 0.057 . . 0.088 0.337 0.184 0.415 0.415 0.415 0.415 0.415 0.415 0.415 0.782 0.782 0.782 0.782 . . . 0.236 . . . . . . . . . . . . . 0.212 . . . 0.214 . 0.192 . . 0.193 . 0.355 0.321 0.059 -0.042 -0.042 . . . . . . . . 0.16 0.105 . 0.158 0.095 0.091 0.091 0.167 0.365 0.48 0.332 . 0.539 0.139 0.432 3.039 3.039 3.039 -0.072 0.266 0.266

rs790591914 rs792178346 rs786766926 rs787692147 . rs788184220 rs786964156 rs793641251 rs787635637 rs788498102 rs791598326 rs792206716 rs792206716 rs792206716 rs792206716 rs792206716 rs792206716 rs792206716 rs790406966 rs790406966 rs790406966 rs790406966 rs792431099 rs790756884 rs790756884 rs786958891 rs790055442 rs788642381 rs787588125 rs793506657 rs788733873 rs787687596 rs791048923 rs789499714 rs789732194 rs789732194 rs789732194 rs789732194 rs789732194 rs787666160 rs791749371 482233 rs7911 . rs790965704 rs787253601 rs789544291 rs793608651 . rs790820786 rs792384781 rs792100215 rs787944163 rs788616054 086603 rs7870 086603 rs7870 . rs789239446 . rs793429697 rs788226555 rs791884275 rs787399676 rs790126169 rs791300667 rs787242792 rs787968075 195378 rs7916 rs787319455 rs788582524 rs788582524 . rs791792379 rs792217786 rs791644106 rs789214604 rs790505038 . 640622 rs7888 rs792757274 rs792757274 rs792757274 214314 rs7910 rs789634854 rs789634854

2 2 3 2 2 2 2 2 3 6 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 3 2 2 3 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 3 3

ACAT.ATGT AAAC.GTTT ATCC.GGAT AAAAC.GTTTT AATG.CATT AAAAC.GTTTT AG.CT AAC.GTT AC.GT AAAC.GTTT AT.AT AT.AT AT.AT AT.AT AT.AT AAAAC.GTTTT AAAT.ATTT AAAT.ATTT AT.AT AAT.ATT AAAT.ATTT AAAAC.GTTTT ACC.GGT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAAC.GTTTT AAAAC.GTTTT AAAAC.GTTTT AT.AT AAAT.ATTT ACAT.ATGT ACAT.ATGT ACAT.ATGT AC.GT AC.GT AC.GT AC.GT AC.GT AC.GT AC.GT AC.GT AAAAAC.GTTTTT AG.CT AC.GT AAAT.ATTT AAAT.ATTT AAAT.ATTT AC.GT AAT.ATT AT.AT AT.AT AAC.GTT AAAC.GTTT AAAAT.ATTTT AAT.ATT AAATG.CATTT AAAC.GTTT AAT.ATT AAAC.GTTT AT.AT AC.GT AAC.GTT AC.GT AC.GT AG.CT AT.AT AT.AT AT.AT AAT.ATT AAT.ATT AAAC.GTTT AAAAT.ATTTT AAT.ATT AC.GT AG.CT AAC.GTT AAC.GTT AAAAC.GTTTT AT.AT AT.AT AAAT.ATTT

X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X

65389689 65400053 65566986 65941713 66091912 66445214 66541199 66562845 66699179 66952756 66972899 66972899 67054811 67054811 67054811 67370573 67391494 67545239 67639602 67655991 68280378 68384436 68392676 68445285 68445285 68445285 68445285 68445285 68687380 68687380 68687380 69256911 70246369 70430505 70430505 70430505 70665103 70665103 70665103 70681287 70681287 70681287 70681287 70681287 70813006 71079040 71252168 71327075 71327075 71327075 71734736 71746209 71769157 71842458 72337387 72338356 72376884 72387554 72433095 72451133 72477193 72611180 72729237 72809015 72827991 73528807 73723153 73770849 73886236 73886236 73886236 73972617 73972617 74247486 74377712 74423790 74797907 74810517 75033179 75048010 75110632 75541614 75551020 75575793

65389704 65400074 65567021 65941736 66091933 66445232 66541214 66562858 66699191 66952777 66972909 66972909 67054824 67054824 67054824 67370591 67391508 67545253 67639629 67656017 68280407 68384452 68392691 68445300 68445300 68445300 68445300 68445300 68687397 68687397 68687397 69256929 70246387 70430521 70430521 70430521 70665119 70665119 70665119 70681296 70681296 70681296 70681296 70681296 70813031 71079064 71252177 71327103 71327103 71327103 71734753 71746223 71769168 71842469 72337399 72338370 72376898 72387566 72433122 72451147 72477211 72611204 72729246 72809024 72828011 73528825 73723163 73770865 73886245 73886245 73886245 73972630 73972630 74247500 74377728 74423809 74797923 74810529 75033196 75048040 75110660 75541627 75551031 75575811

4 5.5 9 4.8 5.5 3.8 8 4.66667 6.5 5.5 5.5 5.5 7 7 7 3.8 3.75 3.75 14 9 7.5 3.4 5.33333 4 4 4 4 4 3.6 3.6 3.6 9.5 4.75 4.25 4.25 4.25 8.5 8.5 8.5 5 5 5 5 5 4.33333 12.5 5 7.25 7.25 7.25 9 5 6 6 4.33333 3.75 3 4.33333 5.6 3.75 6.33333 6.25 5 5 7 9.5 5.5 8.5 5 5 5 4.66667 4.66667 3.75 3.4 6.66667 8.5 6.5 6 10.3333 5.8 7 6 4.75

. . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000013570 . intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000030959 CDX4 intron ENSSSCT00000034899 CDX4 intron ENSSSCT00000013576 CHIC1 intron ENSSSCT00000034312 CHIC1 intron ENSSSCT00000033759 CHIC1 intron . . intergenic ENSSSCT00000020222 . promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000036440 ABCB7 intron ENSSSCT00000036358 ABCB7 intron ENSSSCT00000032985 ABCB7 intron ENSSSCT00000013585 ABCB7 intron ENSSSCT00000033898 ABCB7 intron ENSSSCT00000013586 UPRT promoter ENSSSCT00000035125 UPRT promoter ENSSSCT00000033503 UPRT promoter . . intergenic . . intergenic ENSSSCT00000035999H242-77E21 intron ENSSSCT00000036604 ATRX intron ENSSSCT00000013595 ATRX intron ENSSSCT00000036604 ATRX intron ENSSSCT00000034791 ATRX intron ENSSSCT00000013595 ATRX intron ENSSSCT00000034747 ATRX intron ENSSSCT00000036604 ATRX intron ENSSSCT00000036526 ATRX intron ENSSSCT00000013596 ATRX intron ENSSSCT00000013595 ATRX promoter ENSSSCT00000035022 MAGT1 3'utr . . intergenic . . intergenic ENSSSCT00000029310 TAF9B intron ENSSSCT00000033907 TAF9B intron ENSSSCT00000023290 TAF9B intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000033871H242-123K1 intron ENSSSCT00000033174H242-123K1 intron ENSSSCT00000031239H242-123K1 intron ENSSSCT00000033174H242-123K1 intron ENSSSCT00000031239H242-123K1 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic

0.208 . 0.207 0.431 0.988 0.274 . . . . 0.243 0.243 0.388 0.388 0.388 . . . . . 0.278 0.335 0.098 0.475 0.475 0.475 0.475 0.475 0.236 0.236 0.236 -0.044 . 0.275 0.275 0.275 0.261 0.261 0.261 0.454 0.454 0.454 0.454 0.454 0.564 . . . . . . 0.17 . . . . . . . . 0.025 . . -0.229 . . . . 0.138 0.138 0.138 0.142 0.142 0.27 . . . . . . . . . .

. rs791620242 rs793148681 rs791773164 rs788916292 rs792978486 rs787998638 rs787662462 rs787300540 rs793349905 rs789920426 rs789920426 rs791738866 rs791738866 rs791738866 rs787565489 rs788278582 rs793600060 rs792412868 rs787611239 rs790307588 . . rs786326208 rs786326208 rs786326208 rs786326208 rs786326208 rs789434264 rs789434264 rs789434264 rs788079280 223895 rs7901 rs788575186 rs788575186 rs788575186 rs788883380 rs788883380 rs788883380 . . . . . rs791347800 rs792850813 . 347660 rs7886 347660 rs7886 347660 rs7886 rs791218449 rs792701856 rs788532882 rs792985978 rs787111826 rs790706996 rs789557316 rs791364033 rs787617817 . rs790657483 rs787830843 rs790516349 rs786603809 rs789357093 . . rs789773029 . . . . . 602431 rs7932 rs793428251 rs793010287 rs787158234 . rs789327056 rs792288922 rs789323168 rs792090473 rs790752513 .

2 2 2 2 2 2 2 3 2 2 2 2 3 3 3 2 2 2 5 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2

AAT.ATT AAAAT.ATTTT AG.CT AAAC.GTTT AG.CT AT.AT AT.AT AAAC.GTTT AAAC.GTTT AG.CT AT.AT AAAAC.GTTTT AAAG.CTTT AT.AT AGAT.ATCT AG.CT AT.AT AAAT.ATTT AG.CT AAAT.ATTT AT.AT AT.AT AG.CT AC.GT AAG.CTT AT.AT AAT.ATT AG.CT AGAT.ATCT AATG.CATT AT.AT AAAT.ATTT AAC.GTT AC.GT AAC.GTT AT.AT AAAT.ATTT AAC.GTT AC.GT AT.AT AC.GT AC.GT AT.AT AT.AT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAC.GTTT AC.GT AC.GT AAAAAC.GTTTTT AAAAC.GTTTT AC.GT AATC.GATT AG.CT AAAT.ATTT AAAC.GTTT AC.GT AT.AT AG.CT AC.GT AAAC.GTTT AC.GT ACT.AGT AGAT.ATCT AC.GT AC.GT AAAC.GTTT AT.AT AC.GT AAAAC.GTTTT AT.AT AAAC.GTTT AAAT.ATTT AGAT.ATCT AAAG.CTTT AAAT.ATTT AAAT.ATTT AAAC.GTTT AT.AT AAG.CTT AT.AT AT.AT AT.AT

X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X

76258124 76453880 76578223 76721441 76778848 77182594 77182594 77252488 77252488 77302879 77409737 77426728 77469995 77674789 77850649 77883085 77886868 77917804 77970396 78198920 78271280 78417726 78471671 78613889 78640813 78714289 79790981 80433727 80752189 80770513 80871968 80877211 80945255 80971422 81037779 81075568 81219804 81297953 81423436 81640264 82201715 82646963 82661958 82701367 83109358 84691923 84751574 84890326 84962729 85196155 85232036 85251358 85263535 85587348 85638738 85681234 85767148 85785075 85884987 85996454 86072902 86084158 86424582 86462304 86497780 86678395 86914676 86994934 87171089 87346134 87704040 87763440 87804721 87827744 87849896 87924537 88091977 88178346 88357937 88366850 88417897 88537354 88546575 88591540

76258141 76453903 76578243 76721471 76778858 77182605 77182605 77252514 77252514 77302899 77409752 77426760 77470021 77674808 77850668 77883104 77886877 77917819 77970408 78198937 78271301 78417737 78471693 78613898 78640824 78714301 79791006 80433741 80752222 80770539 80871978 80877232 80945270 80971432 81037790 81075578 81219824 81297969 81423457 81640284 82201725 82646977 82661968 82701376 83109377 84691938 84751597 84890358 84962741 85196168 85232060 85251375 85263561 85587371 85638749 85681248 85767179 85785084 85884998 85996463 86072923 86084178 86424594 86462325 86497806 86678409 86914688 86994948 87171102 87346145 87704073 87763458 87804734 87827759 87849914 87924549 88091997 88178360 88357952 88366860 88417912 88537365 88546587 88591552

6 4.8 10.5 7.75 5.5 6 6 6.75 6.75 10.5 8 6.6 6.75 10 5 10 5 4 6.5 4.5 11 6 11.5 5 4 6.5 8.66667 7.5 8.5 6.75 5.5 5.5 5.33333 5.5 4 5.5 5.25 5.66667 11 10.5 5.5 7.5 5.5 5 5 4 6 8.25 6.5 7 4.16667 3.6 13.5 6 6 3.75 8 5 6 5 11 5.25 6.5 7.33333 6.75 7.5 6.5 3.75 7 6 6.8 9.5 3.5 4 4.75 3.25 5.25 3.75 4 5.5 5.33333 6 6.5 6.5

. . . . . ENSSSCT00000032934 ENSSSCT00000013622 ENSSSCT00000013622 ENSSSCT00000032934 . . . . . . . . . . ENSSSCT00000029661 . . . . . . . . . . . . ENSSSCT00000013634 ENSSSCT00000013634 . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000013641 ENSSSCT00000013641 ENSSSCT00000013641 ENSSSCT00000028335 ENSSSCT00000028335 ENSSSCT00000028335 ENSSSCT00000028335 . . . . . . . . . . . . . . . . . .

. . . . . RPS6KA6 RPS6KA6 RPS6KA6 RPS6KA6 . . . . . . . . . . . . . . . . . . . . . . . KLHL4 KLHL4 . . . . . . . . . . . . . . . . . . . . . . . . . DIAPH2 DIAPH2 DIAPH2 . . . . . . . . . . . . . . . . . . . . . .

intergenic intergenic intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

. . . -0.036 . . . . . . 0.15 0.876 -0.029 . . . . 0.373 . . . . 0.24 . -0.031 0.259 -0.012 . . . . . . 3.287 . . . . . . . . . . . . 0.217 0.152 0.179 0.361 . . . 0.052 0.388 0.271 0.239 0.005 . 0.045 0.103 0.065 0.176 0.313 0.356 0.267 0.189 0.082 0.112 . 0.046 0.051 -0.081 . . 0.212 0.152 -0.256 0.197 . 0.059 -0.071 0.068 0.057

rs788566218 rs793462338 rs793429248 673506 rs7898 rs792010964 rs793318647 rs793318647 rs791505897 rs791505897 . rs793559558 . . rs791966059 rs789515026 rs786742640 rs789033272 rs791299010 rs791279021 . rs786582178 rs790941312 rs692863645 rs791690546 . rs787555762 rs793417337 . 735620 rs7937 rs787993169 . rs789982113 rs792596337 rs793375645 . rs789055204 rs791822041 rs791214461 . rs791138283 rs789087231 rs786596897 rs792221130 rs788521438 rs788760320 rs792454875 rs792293298 rs791625988 . . rs788091451 rs788832750 rs788312270 rs787067504 rs787667382 rs793746266 rs788303683 . rs787903219 rs788735007 rs791976114 . rs793010480 . . rs792746525 rs790822403 . . rs787904480 258841 rs7902 rs789563160 905683 rs7935 rs793566937 rs791133929 . . rs786433735 rs792416875 rs789203542 . rs791451474 258104 rs7872 .

4 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 4 2 2 5 2 2 2 2 2 2 2 2 2 2 2 2 2 4 2 3 2 2 2 2 2 2 2 2 2 3 2 2 2 2 3 2 2 2 2 2 2 3 2 2 2 2 2 2 2

AAAC.GTTT AAT.ATT AC.GT AAAAT.ATTTT AT.AT AG.CT AAC.GTT AAAT.ATTT AGAT.ATCT ATC.GAT AAAC.GTTT AC.GT AC.GT AAAT.ATTT AAAT.ATTT AAACC.GGTTT AAACC.GGTTT AAACC.GGTTT AAACC.GGTTT AAACC.GGTTT AAACC.GGTTT AAACC.GGTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAT.ATT AAAT.ATTT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AAC.GTT AAAAAC.GTTTTT AAAAAC.GTTTTT AC.GT AATT.AATT AT.AT AC.GT AC.GT ACAT.ATGT AT.AT AAT.ATT AT.AT AAAAG.CTTTT AG.CT AC.GT AT.AT AT.AT AC.GT AT.AT AAATT.AATTT AT.AT AT.AT AT.AT AT.AT AT.AT AAAT.ATTT AC.GT AAAAC.GTTTT AAAAT.ATTTT AGAGG.CCTCT AAAAAG.CTTTTT AT.AT AAAT.ATTT AC.GT AAAAT.ATTTT AAC.GTT AT.AT AAG.CTT AAAC.GTTT AATT.AATT AAAAC.GTTTT AT.AT AGAT.ATCT AC.GT AT.AT AT.AT AG.CT AG.CT AAAT.ATTT AC.GT AT.AT AAAC.GTTT ACT.AGT

X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X

88621593 88626441 88944350 88968854 89040476 89083959 89159435 89273313 89286220 89941478 90140448 90210338 90321507 90351663 90370413 90399818 90399818 90399818 90399818 90399818 90399818 90399818 90705802 90705802 90705802 90771894 90774615 90903174 90903174 90903174 90903174 90903174 90978438 90978438 91039664 91104403 91166172 91361386 91452428 91468249 91540863 91670013 91690894 91820080 91834159 91842449 91893787 91899312 91904327 92163159 92380684 92691872 93038534 93138674 93307451 93447199 93588385 93650191 93665578 93746242 93862216 93930709 93973448 93982840 94014315 94174496 94283897 94285592 94394594 95122360 95123003 95209585 95367674 95669006 96397935 96478413 96506326 96517114 96531396 96562034 96633657 96637405 96665561 96722582

88621608 88626462 88944366 88968871 89040487 89083979 89159463 89273331 89286243 89941494 90140474 90210367 90321518 90351683 90370431 90399837 90399837 90399837 90399837 90399837 90399837 90399837 90705825 90705825 90705825 90771912 90774638 90903188 90903188 90903188 90903188 90903188 90978459 90978459 91039696 91104428 91166183 91361408 91452447 91468274 91540874 91670027 91690909 91820097 91834173 91842458 91893798 91899322 91904337 92163180 92380700 92691881 93038544 93138690 93307461 93447222 93588399 93650204 93665596 93746261 93862230 93930737 93973461 93982861 94014327 94174518 94283910 94285602 94394621 95122387 95123024 95209603 95367687 95669044 96397947 96478436 96506336 96517138 96531407 96562052 96633689 96637416 96665584 96722594

4 7.33333 8.5 3.6 6 10.5 9.66667 4.75 6 5.66667 6.75 15 6 5.25 4.75 4 4 4 4 4 4 4 6 6 6 6.33333 6 5 5 5 5 5 3.66667 3.66667 16.5 6.5 6 11.5 10 6.5 6 5 8 3.6 7.5 5 6 5.5 5.5 11 3.4 5 5.5 8.5 5.5 12 3.75 7 3.8 4 3 4.83333 7 5.5 6.5 4.6 4.66667 5.5 9.33333 7 5.5 3.8 7 9.75 6.5 12 5.5 12.5 6 4.75 16.5 6 6 4.33333

. . . . . . . . . ENSSSCT00000013646 . . . . . ENSSSCT00000034722 ENSSSCT00000034276 ENSSSCT00000034376 ENSSSCT00000027214 ENSSSCT00000013653 ENSSSCT00000033718 ENSSSCT00000035264 ENSSSCT00000013658 ENSSSCT00000032805 ENSSSCT00000035785 . . ENSSSCT00000032924 ENSSSCT00000033286 ENSSSCT00000034812 ENSSSCT00000033320 ENSSSCT00000036590 ENSSSCT00000013660 ENSSSCT00000032946 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ENSSSCT00000023372 . . . . . . . . . . . . . . .

. . . . . . . . . . . . . . . CSTF2 CSTF2 CSTF2 CSTF2 CSTF2 CSTF2 CSTF2 CENPI CENPI CENPI . . DRP2 DRP2 DRP2 DRP2 DRP2 TAF7L TAF7L . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intron intron intron promoter intergenic intergenic promoter promoter promoter promoter promoter intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic cds intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

0.12 0.192 . 0.365 0.221 -0.04 -0.062 0.044 0.074 0.37 0.458 1.668 0.465 . . 0.238 0.238 0.238 0.238 0.238 0.238 0.238 . . . . 0.205 0.341 0.341 0.341 0.341 0.341 0.341 0.341 0.406 . 0.146 . . . 0.217 0.123 . . . . 0.087 -0.024 . 0.086 0.253 0.067 0.119 . 0.927 . 0.034 . . 0.761 . . . 0.021 -0.132 0.294 0.09 -1.291 . . . 0.188 -0.223 . . . -0.226 . . 0.169 . -0.018 . .

rs787942322 . rs789789067 rs791565972 rs793399678 rs792963307 rs787206193 rs791160654 rs788742084 rs792077542 rs787833304 rs792946364 566178 rs7913 rs786779991 rs792093689 rs789305427 rs789305427 rs789305427 rs789305427 rs789305427 rs789305427 rs789305427 . . . rs791382239 rs789060664 rs786762987 rs786762987 rs786762987 rs786762987 rs786762987 rs790382962 rs790382962 rs786583234 rs792729921 rs789592035 rs789888369 . 851302 rs7921 rs792753400 rs792253691 . rs790651578 rs789875055 rs786681627 rs793104776 rs792358222 . rs787267750 rs787459905 . . rs788205007 rs789926969 rs792490935 . rs791536584 rs792177801 rs787602762 rs793057812 rs787574849 rs790490206 rs793794887 . rs790791827 . rs788547646 rs788365930 rs790934583 rs793100888 rs787109511 . rs788569040 rs790419754 rs793256035 165407 rs7927 rs787902160 rs790360831 rs788339648 rs787575456 rs788056355 . rs790308767

2 2 2 2 2 2 4 2 2 2 4 4 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 3 2 2 2 2 3 2 3 4 2 2 3 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2

AAAC.GTTT AC.GT AT.AT AT.AT AC.GT AATC.GATT AAAAC.GTTTT ACC.GGT AAAAC.GTTTT AT.AT AATT.AATT AC.GT AAAC.GTTT AAAAC.GTTTT AAC.GTT AC.GT AG.CT AG.CT AAC.GTT AC.GT AC.GT AC.GT AC.GT AC.GT AC.GT AC.GT AG.CT AT.AT AAAAT.ATTTT AC.GT AC.GT AT.AT AAATT.AATTT AT.AT AT.AT AAC.GTT AT.AT AAAAAC.GTTTTT AC.GT AG.CT AAAAC.GTTTT AC.GT AT.AT AAAAT.ATTTT AC.GT AT.AT AG.CT AAAC.GTTT AAC.GTT AAC.GTT AC.GT AAAC.GTTT AAAC.GTTT AAAG.CTTT AG.CT AAAC.GTTT AC.GT AC.GT AT.AT AT.AT AAAC.GTTT AG.CT AT.AT AG.CT AG.CT AG.CT AG.CT AC.GT AAC.GTT AT.AT AG.CT ACCAGG.CCTGG AGG.CCT AT.AT AG.CT AG.CT GGGGC.GCCCC AC.GT AAAC.GTTT AAT.ATT AC.GT AGATAT.ATATCT AT.AT AC.GT

X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X

96794662 96823495 97011874 97131339 97383980 97437677 97483740 97660007 97702243 97734981 97782979 98013674 98116852 98201560 98217160 98236628 98319098 98373789 98485944 98653083 98653083 98653083 98653083 98653083 98653083 99003665 99278225 99554770 99620011 99666562 99835071 99840623 99859168 99883292 99900764 100093204 100493244 100502265 100510477 100519919 100753257 100885724 100908660 100982772 101041997 101124118 101191660 101397263 101664158 101664158 101933014 102222083 102497447 102545747 102766750 102900122 103654797 103808191 103961009 104660299 104718083 105890024 106594064 106833430 106833430 106833430 106882727 106894298 107146200 107222785 107289908 107433427 107482105 107889912 108735351 109462755 109464104 110035250 110480278 110551295 110555969 110826918 110878079 111083579

96794680 96823507 97011885 97131351 97383989 97437703 97483765 97660020 97702262 97734992 97783000 98013689 98116876 98201585 98217175 98236638 98319108 98373803 98485957 98653111 98653111 98653111 98653111 98653111 98653111 99003676 99278237 99554779 99620032 99666573 99835081 99840645 99859188 99883305 99900775 100093224 100493265 100502296 100510487 100519937 100753276 100885734 100908671 100982789 101042006 101124129 101191669 101397281 101664171 101664171 101933027 102222105 102497484 102545767 102766764 102900139 103654815 103808205 103961024 104660309 104718106 105890035 106594074 106833442 106833442 106833442 106882738 106894309 107146213 107222796 107289920 107433446 107482119 107889931 108735364 109462765 109464123 110035262 110480299 110551313 110555989 110826948 110878089 111083588

4.75 6.5 6 6.5 5 6.75 5.2 4.66667 4 6 5.5 8 6.25 5.2 5.33333 5.5 5.5 7.5 4.66667 14.5 14.5 14.5 14.5 14.5 14.5 6 6.5 5 4.4 6 5.5 11.5 4.2 7 6 7 11 5.33333 5.5 9.5 4 5.5 6 3.6 5 6 5 4.75 4.66667 4.66667 7 5.75 9.5 5.25 7.5 4.5 9.5 7.5 8 5.5 6 6 5.5 6.5 6.5 6.5 6 6 4.66667 6 6.5 3.33333 5 10 7 5.5 3.33333 6.5 5.5 6.33333 10.5 5.16667 5.5 5

. . . . . . . . . . . ENSSSCT00000013694 . . . . . . . ENSSSCT00000033539 ENSSSCT00000035182 ENSSSCT00000035493 ENSSSCT00000034814 ENSSSCT00000013705 ENSSSCT00000033433 . . ENSSSCT00000034930 ENSSSCT00000034930 ENSSSCT00000034930 ENSSSCT00000034930 ENSSSCT00000034930 ENSSSCT00000034930 ENSSSCT00000034930 ENSSSCT00000034930 ENSSSCT00000034930 ENSSSCT00000034930 ENSSSCT00000034930 ENSSSCT00000034930 ENSSSCT00000034930 ENSSSCT00000034930 . ENSSSCT00000035651 ENSSSCT00000013716 . . . ENSSSCT00000013721 ENSSSCT00000013724 ENSSSCT00000035728 ENSSSCT00000013728 . ENSSSCT00000013734 . ENSSSCT00000013739 . . . ENSSSCT00000013749 . . . . ENSSSCT00000033227 ENSSSCT00000036569 ENSSSCT00000013769 . . . . . . . . ENSSSCT00000035084 ENSSSCT00000013776 ENSSSCT00000013776 . . . . . . .

. intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . promoter . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic PLP1 intron PLP1 intron PLP1 intron PLP1 intron PLP1 intron PLP1 intron . intergenic . intergenic IL1RAPL2 intron IL1RAPL2 intron IL1RAPL2 intron IL1RAPL2 intron IL1RAPL2 intron IL1RAPL2 intron IL1RAPL2 intron IL1RAPL2 intron IL1RAPL2 intron IL1RAPL2 intron IL1RAPL2 intron IL1RAPL2 intron IL1RAPL2 intron IL1RAPL2 intron . intergenic NRK intron . intron . intergenic . intergenic . intergenic . intron TBC1D8B intron TBC1D8B intron RBM41 intron . intergenic FRMPD3 intron . intergenic MID2 intron . intergenic . intergenic . intergenic AMMECR1 intron . intergenic . intergenic . intergenic . intergenic LHFPL1 intron LHFPL1 intron LHFPL1 intron . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic HTR2C intron PLS3 intron PLS3 intron . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic . intergenic

. . . . . . . -0.148 . . . 0.185 0.139 -0.145 -0.081 0.111 . 0.461 0.229 1.589 1.589 1.589 1.589 1.589 1.589 0.189 0.327 . 0.025 0.103 0.215 . 0.071 0.214 0.393 . 0.18 0.232 0.358 0.18 0.618 . 0.19 0.299 0.148 . 0.186 0.329 . . . 0.308 0.28 0.214 0.219 0.231 0.086 0.283 0.468 . 0.282 0.155 0.235 -0.041 -0.041 -0.041 . . . . . 0.023 0.559 . 0.107 0.088 0.273 0.038 0.192 0.157 -0.053 0.337 0.245 .

rs789225210 rs789560253 rs793772649 rs786571001 rs790892118 856813 rs7885 rs788715285 . . rs793022127 rs786422323 rs791511199 rs789459856 rs791101592 rs793797775 rs789663279 rs789652629 rs786459861 rs791036096 . . . . . . rs792976538 rs786525179 . rs790231431 rs789982958 rs788891399 rs787663403 . rs790555507 rs791052868 rs793662628 rs789628846 . . . rs786915026 rs787786823 rs788173567 rs790355688 rs788474466 rs789218015 rs793413130 rs786890164 rs789047898 rs789047898 rs787824541 rs789788039 802214 rs7922 rs792386451 rs789004582 rs789469796 . 389872 rs7897 rs791113642 rs787730772 rs791114678 . rs787139034 . . . rs790053740 rs789236363 rs791741145 rs787145282 . . rs793428613 rs790872554 . rs790817181 rs793030958 rs789990293 rs788368961 rs792732897 rs788988815 rs793494037 . .

2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 3 3 3 3 3 3 2 2 4 2 2 3 2 2 2 2 2 2 2 4 2 2 3 3 2 2 2 2 2 2 2 3 2 4 2 2 2 2 2 2 2 2 2 2 3 3 3 2 2 2 2 2 2 2 2 4 2 2 2 2 2 2 2 2 4

AT.AT AT.AT AT.AT AAAAC.GTTTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAAC.GTTTT AAAT.ATTT AAAT.ATTT AAAAAC.GTTTTT AAAAAC.GTTTTT AAAAAC.GTTTTT AAAAAC.GTTTTT AT.AT AT.AT AAAC.GTTT AAAC.GTTT ATCC.GGAT AT.AT AT.AT AT.AT AAAC.GTTT AAG.CTT AG.CT AAC.GTT AG.CT AC.GT AAAC.GTTT AAAC.GTTT AT.AT AT.AT AAT.ATT AAAAC.GTTTT AAT.ATT AC.GT AAAAC.GTTTT AT.AT AC.GT AG.CT AAC.GTT AC.GT AG.CT AT.AT AT.AT AG.CT AAC.GTT AAAAC.GTTTT AG.CT AAAT.ATTT AAAT.ATTT AAAT.ATTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAT.ATTT AAAC.GTTT AAAC.GTTT AG.CT AG.CT AG.CT AG.CT AC.GT AAC.GTT AG.CT AAAC.GTTT AAC.GTT AGGGC.GCCCT AC.GT AAC.GTT AT.AT AC.GT AAC.GTT AATTAG.CTAATT

X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X

111157127 111217765 111388646 111816511 113122832 113610965 113610965 113610965 113610965 113610965 113610965 113610965 113610965 113610965 113648716 113648716 113648716 113720695 114461047 114461047 114485716 114485716 114485716 114485716 114498608 114498608 114547891 114547891 115024835 115718167 115718167 115718167 116374435 116489113 116534044 116723274 117092101 117116792 117258195 117258195 117579380 117581945 117611033 117687477 117719241 118109367 118163715 118662866 118702361 118911571 118914116 118968737 119390409 119473622 119652451 120886661 120939955 121311469 121324586 121935312 121935312 121935312 121998310 122133590 122217874 122286230 122561557 122561557 122940691 122940691 122940691 123652038 123868435 124018096 124033403 124033820 124134751 124407155 124413324 124466449 124474936 124558135 124998276 125201122

111157139 111217779 111388664 111816529 113122845 113610981 113610981 113610981 113610981 113610981 113610981 113610981 113610981 113610981 113648745 113648745 113648745 113720713 114461062 114461062 114485738 114485738 114485738 114485738 114498618 114498618 114547918 114547918 115024864 115718177 115718177 115718177 116374455 116489129 116534056 116723291 117092117 117116809 117258222 117258222 117579389 117581957 117611054 117687505 117719255 118109378 118163743 118662878 118702371 118911603 118914135 118968748 119390419 119473637 119652462 120886670 120939970 121311483 121324596 121935325 121935325 121935325 121998328 122133606 122217892 122286252 122561573 122561573 122940705 122940705 122940705 123652048 123868445 124018111 124033413 124033834 124134763 124407178 124413341 124466469 124474945 124558145 124998289 125201143

6.5 7.5 9.5 3.8 3.5 4.25 4.25 4.25 4.25 4.25 4.25 4.25 4.25 4.25 7.5 7.5 7.5 3.8 4 4 3.83333 3.83333 3.83333 3.83333 5.5 5.5 7 7 7.5 5.5 5.5 5.5 5.25 5.66667 6.5 6 8.5 9 7 7 5 6.5 7.33333 5.8 5 6 5.8 6.5 5.5 16.5 6.66667 6 5.5 8 6 5 5.33333 3 5.5 3.5 3.5 3.5 4.75 4.25 4.75 5.75 4.25 4.25 7.5 7.5 7.5 5.5 5.5 5.33333 5.5 3.75 4.33333 4.8 9 7 5 5.5 4.66667 3.66667

. . . . . ENSSSCT00000013798 ENSSSCT00000035968 ENSSSCT00000035573 ENSSSCT00000035644 ENSSSCT00000034429 ENSSSCT00000034508 ENSSSCT00000033202 ENSSSCT00000036221 ENSSSCT00000034740 ENSSSCT00000013799 ENSSSCT00000036344 ENSSSCT00000034398 . ENSSSCT00000013815 ENSSSCT00000035722 ENSSSCT00000013815 ENSSSCT00000013815 ENSSSCT00000035005 ENSSSCT00000035722 ENSSSCT00000013815 ENSSSCT00000035722 ENSSSCT00000013815 ENSSSCT00000035722 . ENSSSCT00000013819 ENSSSCT00000032933 ENSSSCT00000036560 ENSSSCT00000013823 . . . ENSSSCT00000033370 ENSSSCT00000033370 ENSSSCT00000033370 ENSSSCT00000030109 . . . . . . . . . . . . . . . . . . . ENSSSCT00000013831 ENSSSCT00000035468 ENSSSCT00000036143 . . . . ENSSSCT00000013840 ENSSSCT00000033263 ENSSSCT00000034092 ENSSSCT00000026646 ENSSSCT00000035630 . . . . . . . . . . . . .

. . . . . 6-Sep 6-Sep 6-Sep 6-Sep 6-Sep 6-Sep 6-Sep 6-Sep 6-Sep NKRF NKRF NKRF . . DOCK11 . . DOCK11 DOCK11 . DOCK11 . DOCK11 . GRIA3 GRIA3 GRIA3 STAG2 . . . TENM1 TENM1 TENM1 U2 . . . . . . . . . . . . . . . . . . . OCRL OCRL OCRL . . . . ZNF280C ZNF280C ENOX2 ENOX2 ENOX2 . . . . . . . . . . . . .

intergenic intergenic intergenic intergenic intergenic intron intron intron intron intron intron intron intron intron intron intron promoter intergenic intron intron cds intron intron intron intron intron intron intron intergenic intron intron intron intron intergenic intergenic intergenic intron intron intron promoter intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intergenic intergenic intergenic intergenic intron intron intron intron intron intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic intergenic

0.132 0.137 . 0.05 -0.546 -0.335 -0.335 -0.335 -0.335 -0.335 -0.335 -0.335 -0.335 -0.335 . . . . -0.063 -0.063 0.434 0.434 0.434 0.434 0.145 0.145 0.297 0.297 0.068 . . . 0.229 0.359 0.161 1.23 0.084 1.655 . . 0.219 0.282 0.513 0.437 0.496 0.063 0.477 0.218 0.006 0.083 0.171 -0.067 -0.144 . . 0.469 . 0.353 0.582 0.171 0.171 0.171 0.303 0.087 0.097 . 0.18 0.18 -1.025 -1.025 -1.025 0.262 0.108 . . . 0.056 0.159 . . 0.237 . 0.01 0.034

638402 rs7873 rs788589024 rs788868843 903347 rs7862 rs792888886 712620 rs7881 712620 rs7881 712620 rs7881 712620 rs7881 712620 rs7881 712620 rs7881 712620 rs7881 712620 rs7881 712620 rs7881 . . . rs792382169 828734 rs7887 828734 rs7887 rs792712529 rs792712529 rs792712529 rs792712529 . . rs792302123 rs792302123 rs787283372 rs789414883 rs789414883 rs789414883 rs792581610 rs787664252 rs790791408 rs786593162 . . . . rs792056007 . rs791836397 rs789538764 rs789519529 675609 rs6920 rs792046128 rs788554439 . rs789546047 rs793621895 rs792468071 . rs792127392 rs791754764 rs790407818 rs793605184 rs793469258 rs786227941 575467 rs7905 575467 rs7905 575467 rs7905 rs792123574 rs790202669 rs786317082 rs787625612 rs790173553 rs790173553 . . . rs790137626 rs698983496 823309 rs7926 . rs786808447 rs792426782 rs793177907 . 726606 rs7896 . rs789920078 rs787409280 rs792079171

2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 4 3 2 2 2 2 2 2 2 4 2 2 4 2 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 4 2 3 2 2 2 2 2 2 2

AC.GT AC.GT AG.CT AC.GT AAAT.ATTT AC.GT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AAAC.GTTT AG.CT AC.GT AC.GT AC.GT AC.GT AG.CT AAC.GTT AG.CT AT.AT AAAC.GTTT AAAAC.GTTTT AC.GT AT.AT AC.GT AG.CT AG.CT AAC.GTT AAAC.GTTT AT.AT ATCC.GGAT AT.AT AG.CT AAAAC.GTTTT ACAT.ATGT AAAAT.ATTTT AAAT.ATTT AAC.GTT AT.AT AC.GT AAT.ATT AAAC.GTTT AT.AT ACC.GGT AAAC.GTTT AC.GT AAC.GTT AC.GT AG.CT AC.GT AAGG.CCTT AAAG.CTTT AC.GT AT.AT AC.GT AAC.GTT AC.GT AAAC.GTTT AT.AT AAT.ATT AAAT.ATTT AG.CT AC.GT AT.AT AG.CT AC.GT AG.CT AAAG.CTTT AC.GT AT.AT AAAT.ATTT AAAG.CTTT AT.AT AAAT.ATTT AGGG.CCCT AAAAC.GTTTT AACC.GGTT AG.CT AAC.GTT AAG.CTT AC.GT AG.CT

X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X

125308237 125404334 125429690 125829394 126099425 126130088 126302697 126508867 126508867 126508867 126508867 126508867 126508867 126634361 126988477 126988477 126988477 126988477 127621880 128277283 128342746 128408989 128476471 128591545 128665953 128717118 129507081 129652604 129652604 129762391 129863552 129975811 130056644 130472870 130713960 130738543 130912916 130924703 131047687 131276456 131347239 131483414 131541219 132049655 132323268 132407414 132431782 132537838 132808238 132885164 132982207 133160879 133750323 133903733 134242320 134244773 134476434 134883691 135281010 135410416 135461249 135461707 135686088 135867673 136010747 136027366 136045151 136196560 136210862 136387615 136421407 136631517 136841904 136856894 137102925 137484926 137719051 137842009 137994785 138148198 138236855 138442987 138474113 138576943

125308249 125404346 125429700 125829403 126099440 126130106 126302714 126508895 126508895 126508895 126508895 126508895 126508895 126634382 126988486 126988486 126988486 126988486 127621890 128277295 128342763 128408999 128476489 128591568 128665987 128717129 129507107 129652614 129652614 129762409 129863578 129975822 130056665 130472879 130713971 130738562 130912934 130924719 131047709 131276471 131347276 131483425 131541232 132049679 132323280 132407428 132431797 132537855 132808255 132885176 132982217 133160898 133750344 133903746 134242330 134244782 134476446 134883704 135281024 135410434 135461260 135461723 135686101 135867691 136010773 136027379 136045162 136196587 136210871 136387645 136421419 136631534 136841925 136856913 137102936 137484938 137719063 137842032 137994813 138148213 138236883 138443001 138474123 138576952

6.5 6.5 5.5 5 4 9.5 4.5 7.25 7.25 7.25 7.25 7.25 7.25 11 5 5 5 5 5.5 4.33333 9 5.5 4.75 4.8 17.5 6 13.5 5.5 5.5 6.33333 6.75 6 5.5 5 6 4 4.75 3.4 5.75 5.33333 19 6 4.66667 6.25 6.5 5 4 9 6 6.5 5.5 10 5.5 3.5 5.5 5 6.5 4.66667 7.5 4.75 6 5.66667 3.5 9.5 13.5 7 6 14 5 7.75 6.5 9 5.5 5 6 3.25 3.25 4.8 7.25 8 9.66667 5 5.5 5

. . intergenic . . intergenic . . intergenic ENSSSCT00000013862 GPC3 intron . . intergenic . . intergenic . . intergenic ENSSSCT00000034119 FAM122C intron ENSSSCT00000033658 FAM122C intron ENSSSCT00000034247 FAM122C intron ENSSSCT00000035919 FAM122C intron ENSSSCT00000034857 FAM122C intron ENSSSCT00000034621 FAM122C intron . . intergenic ENSSSCT00000033983 DDX26B intron ENSSSCT00000033063 DDX26B intron ENSSSCT00000013878 DDX26B intron ENSSSCT00000033505 DDX26B promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000029012 FGF13 intron ENSSSCT00000021518 ssc-mir-504 promoter . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000013898 MCF2 intron ENSSSCT00000013899 ATP11C intron ENSSSCT00000013899 ATP11C intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000034891H242-176I15promoter . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000036202H242-522I21 intron ENSSSCT00000036202H242-522I21 intron ENSSSCT00000036202H242-522I21 intron ENSSSCT00000036202H242-522I21 intron . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic . . intergenic ENSSSCT00000013917 AFF2 intron ENSSSCT00000013917 AFF2 intron ENSSSCT00000013917 AFF2 intron

0.031 1.11 0.05 0.746 0.5 0.244 . 0.056 0.056 0.056 0.056 0.056 0.056 0.032 0.022 0.022 0.022 0.022 0.939 . . . 0.279 . 0.255 . . 0.195 0.195 -0.004 -0.314 0.134 . 0.207 0.184 0.191 0.392 0.167 0.547 . 0.19 0.115 0.623 0.083 0.01 . 0.056 0.088 . 0.009 . . -0.179 0.005 0.003 0.275 -0.413 -0.151 . . . . . -0.004 . . 0.042 -0.195 0.148 0.076 0.101 . 0.274 . . 0.098 -0.013 0.23 0.084 0.083 0.309 0.462 0.197 0.31

rs789089510 rs792394828 rs792101626 rs787985736 rs790147175 . rs792630423 rs793343825 rs793343825 rs793343825 rs793343825 rs793343825 rs793343825 346866 rs7929 rs786669414 rs786669414 rs786669414 rs786669414 rs701993104 655725 rs7891 rs789573567 rs789833648 rs790344260 rs790788706 . rs788806337 rs788354141 rs788796963 rs788796963 rs792550389 rs789351317 696972 rs7868 rs790413356 rs792392851 rs791997431 807460 rs7923 rs789742404 rs792711403 rs790750720 rs788948555 362047 rs7870 480564 rs7927 rs788520075 . rs788774980 rs792678511 800381 rs7929 . . rs790421315 . . rs792572226 rs787221756 rs789134361 rs786890758 . . rs706115978 rs790308569 rs788699685 rs786560260 rs787431963 rs786728112 rs790614937 . . rs792657051 . rs787025725 rs790521711 rs792199874 rs792133606 rs786662800 rs786215988 rs793724611 . rs786841233 rs792402999 rs787828470 rs790347507 rs786421766 rs790316203 rs790137645

2 2 2 2 2 2 2 2 2 2 2 2 2 4 3 3 3 3 2 2 3 2 2 2 2 2 5 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 2 2 2 4 2 2 3 2 2 2 2 3 3 2 2 2 2 2 2 2 2 3 2 2 2 2 2 2 2 2 2 3 2 2 3 3 2 2 2 2 2

AATG.CATT AC.GT AGAT.ATCT ACAT.ATGT AAC.GTT AT.AT AAAT.ATTT AC.GT AC.GT AC.GT AC.GT AT.AT AC.GT AAAAC.GTTTT AATT.AATT AC.GT AAG.CTT ATCC.GGAT

X X X X X X X X X X X X X X X X X X

138785931 139627871 140346886 140382144 140543095 140595675 140808537 141373574 141373574 141373574 141373574 141407326 142191018 143222896 143853116 143857650 144153854 144159488

138785962 8 . 139627881 5.5 . 140346901 4 . 140382166 5.75 . 140543114 6.66667 . 140595685 5.5 . 140808563 6.75 . 141373588 7.5 ENSSSCT00000034124 141373588 7.5 ENSSSCT00000032639 141373588 7.5 ENSSSCT00000013947 141373588 7.5 ENSSSCT00000033471 141407342 8.5 . 142191030 6.5 . 143222916 4.2 . 143853129 3.5 . 143857662 6.5 . 144153865 4 ENSSSCT00000014028 144159506 4.75 ENSSSCT00000014028

. . . . . . . CETN2 CETN2 CETN2 CETN2 . . . . . PRKX PRKX

intergenic intergenic intergenic intergenic intergenic intergenic intergenic intron intron intron intron intergenic intergenic intergenic intergenic intergenic intron intron

0.047 -0.185 0.184 0.219 . 0.099 0.278 1.202 1.202 1.202 1.202 -0.039 . -0.098 . . . .

876563 rs7930 rs788333674 rs787934905 905994 rs7870 rs788245836 rs793819929 rs790901175 rs788472291 rs788472291 rs788472291 rs788472291 rs793491580 rs791729025 rs790268045 . 383018 rs7911 . .

2 2 2 2 2 2 2 2 2 2 2 4 3 2 2 2 5 2

Supplementary Figure S1.

(b)

120

60

AC*/GT* AT*/AT* AG*/CT* CG*/CG*

Count( x 103 )

60

Count( x 103 )

Motif 90

(c)

AAC*/GTT* AAT*/ATT* AAG*/CTT* AGG*/CCT* AGC*/GCT* ACC*/GGT* ATC*/GAT* CCG*/CGG* ACT*/AGT* ACG*/CGT*

40

Motif AAAT*/ATTT* AAAC*/GTTT* AAAG*/CTTT* AATG*/CATT* AGGG*/CCCT* AAGG*/CCTT* ACAT*/ATGT* ACAG*/CTGT* AATT*/AATT* AATC*/GATT* others

150

100

20

30

50

0

0

0

5 6 7 8 9 10111213141516171819>=20

4

5

6

Repeat Number

7

8

9

3

10 11 >=12

Repeat Number

4

5 6

7

8 9 10 11 >=12

Repeat Number

(e)

(d)

150

150

Motif

Motif AAAAC*/GTTTT* AAAAT*/ATTTT* AAAAG*/CTTTT* ACCCC*/GGGGT* AGGGG*/CCCCT* AAATT*/AATTT* AAATG*/CATTT* AAAGG*/CCTTT* AATAT*/ATATT* CCCCG*CGGGG* others

100

50

Count( x 103 )

Count( x 103 )

200

Motif Count( x 103 )

(a)

AAAAC*/GTTTT* AAAAT*/ATTTT* AAAAG*/CTTTT* ACCCC*/GGGGT* AGGGG*/CCCCT* AAATT*/AATTT* AAATG*/CATTT* AAAGG*/CCTTT* AATAT*/ATATT* CCCCG*CGGGG* others

100

50

0

0 3

4

5

6

7

8

9 >=10

Repeat Number

3

4

5

6

7

8

9 >=10

Repeat Number

Frequency distribution of overall SSRs in reference genome. (a) Dinucleotide, (b) Trinucleotide, (c) Tetranucleotide, (d) Pentanucleotide, (e) Hexanucleotide. The count distribution of different SSRs is classified according to the repeat number of the motif.

Supplementary Figure S2. (b) Di− Tri− Tetra−

150

Penta− Hexa−

6

100

motif

2 0 Promoter 5'UTR CDS 3'UTR Non-coding exon

50

2000

4000

6000

Count( x 103 )

8000

4 AAC*/GTT* AAT*/ATT* AAG*/CTT* AGG*/CCT* AGC*/GCT* ACC*/GGT* ATC*/GAT* CCG*/CGG* ACT*/AGT* ACG*/CGT*

0

0

Density(bp/Mb)

10000 12000

(a)

Intergenic Intron Promotor 5'UTR

CDS 3'UTR

Non-coding exon

Intergenic Intron Promoter 5'UTR

CDS

3'UTR Non-coding exon

Overall SSRs distribution in different genomic region. (a) The distribution of each kind of SSR in different genomic regions. (b) The distribution of trinucleotide SSRs in different genomic regions.

Supplementary Figure S3. (a)

(b)

● ● ● ● ● ● ● ● ● ●

● ●

6

● ●

● ●

● ● ● ●

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● ●

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

●

●

● ●

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●

●

●

● ●

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● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

●

● ● ● ● ●

●

● ● ● ● ● ● ● ● ● ● ● ●

2

4

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

● ● ● ● ● ● ● ● ● ●

6

●

● ● ●

4

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

8

●

Average coverage

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

●

10

●

● ● ● ●

0

0

2

Average coverage

8

10

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

AC

AG

AT

AAC AAG AAT ACC ACG ACT AGC AGG ATC CCG

CG

(d) 1.0

1.0

(c)

●

0.8 0.6

Call rate

0.4

0.8 0.6

● ● ● ● ● ● ● ● ● ●

0.2

0.4

● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

0.0

0.0

0.2

AG

AT

● ● ● ● ● ● ● ●

● ● ● ● ● ● ●

AAC AAG AAT ACC ACG ACT AGC AGG ATC CCG

CG

●

6

●

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

● ●

4

Average coverage

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

● ●

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

●

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

●

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

●

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

0

0.0

0.2

0.4

0.6

0.8

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

8

10

(f) 1.0

(e)

2

Call rate

AC

Call rate

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

n_CG

6_No

G

6_C

n_CG

5_No

5_CG

n_CG

4_No

G

4_C

n_CG

3_No

G

3_C

n_CG

2_No

2_CG

n_CG

G

6_No

6_C

n_CG

5_No

5_CG

n_CG

G

4_No

4_C

n_CG

G

n_CG

3_No

3_C

2_No

2_CG

Motif type effect to Call rate and sequence coverage. (a) The average coverage of different motifs in dinucleotide SSRs. (b) The average coverage of different motifs in trinucleotide SSRs. (c) The call rate of different motifs in dinucleotide SSRs. (d) The call rate of different motifs in trinucleotide SSRs. (e) Comparison of the call rate between CG-containing motifs and non-CG containing motifs. (f) Comparison of the average coverage between CG-containing motifs and non-CG containing motifs. The numbers in (e) and (f) represent different SSR type.

Supplementary Figure S4. (b) 2

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

● ● ● ● ● ● ●

1

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

AC

−1 ●

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

● ● ● ● ● ● ● ●

● ●

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

●

−2

● ● ● ● ●

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

●

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

● ● ● ● ●

●

● ●

● ● ● ● ● ● ● ● ● ●

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

0

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

PhyloP

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

0 −1 −2

PhyloP

1

2

(a)

●

● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●

● ● ● ● ● ● ● ●

● ● ●

● ● ● ● ●

● ● ● ● ● ●

● ● ● ● ● ● ● ● ● ● ●

●

●

● ● ●

●

● ●

AG

AT

CG

AAC AAG AAT ACC ACG ACT AGC AGG ATC CCG

The PhyloP score comparisons among different motifs. (a) Comparison of the PhyloP score in all identified dinucleotide polymorphic SSRs. (b) Comparison of the PhyloP score in all identified trinucleotide polymorphic SSRs.