Chronic Granulomatous Disease with Disseminated

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Chronic Granulomatous Disease ร่วมกับการแพร่กระจายเชื้อ Trichosporonosis : รายงาน ... signs and symptoms of recurrent pyogenic and fungal .... Conjunctivitis.
Chronic GranulomatousDiseasewith : A CaseReport Thichosporonosis Disseminated SamonmaNKanngurn,M.D * PaisarParichariktnond,M.D.+ VisanuPootong,M.D.+* Pakit Vichyanond,M.D.++*

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DUn!{Jru INTRODUCTION choniccnidonriousdnede(ccD) i! rn errrcmelydrc iihdired immunodeficicncydisdile

No hnbry of had injury v6

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CASE REPORT

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pEsenrn b sirinj Hospnalvirh fevcr,h.p!rcpl.' mmeg.ly,picumoniamd dieh6. At tbd rmc, he alsolad r siaEepisode. Luftbd puicdE Evctrled oily nish prcteinin theCSFmd slish y lor susar meninsris H. ws ftded for prc.trdcdrub€rculous

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rob. ricmic with hemdocriiof r9%.Boie nmov pureredccll rplair. Ai uLrmsouidoi rhclbdomci

undormm*rclocicil inve*isationfor orhr c,u*s or h.plrGpl.mmegalyd rollowsvDRr, rnri HIV Hjs hd cMv Iite. all of whhh wercnegative. irlcdionsor childhoodmotuhy wA nored.He

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p,.bolqi. d'nd.arioi Pdtuotu fteautopsyes p.lfomed I d'v anerde{h rnd cvdled a hypodenicboyot 9,1s0Fam oi bodywight *nn miB aDeni, BilsEmllv3up.dichl wd ptrent Bo$ pleumlcavirics lymphtd.nop&n\y *.igh.n 30ostrd230c@q Bpecrivelt cut surfe. show.dnultiplDrbsc*sesor2 cr in harimal di,mch (Fisre l). MiciGcopic fiidins shov.-d Nmdus sm0llandlts. e*nuloEs *ih Nmercls sirn. c.Us,mdt ot vhich areor rorei$ bodvrvpe Somegnnllona .otuidcd sm,ll sPhe hvphre bv psudohtphsandy.an rdr ol runsiprcved (Figuc qp Arr 2). ?t r,'@., dsue cDuurcto bc lymph nodesrsketrtron p0ia*rche'1,hilor.

Fiqlz t. Both ltrdss rcv.il.d meked cois.sdoi

rlso showedmulripl.erhnloms wil\ theo*mjsm 1],e livr *.is[ed 950gEmsandnaltcdly cnla4.d .oi'aiiine multipl. c$eatins iodul.s (FisuE r). sd lords otrbidng thcorslii.m (Figurc4).The spled*6 |'gcd,w.jghilgl4ognn:.G6s'nd micd.opj. fiidings *.F tidils a in lneliv* Thc incritre sho*.d diedcd cmuloms in bothsiosa ,nd subnuco$(F'sre 5).Tle cuxurehln $c ruic lesioi yicldedno grcw|nof AFBrdd orhd brd.na Th. patholosical findiigs A describedabove

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F*d? t\,B rh. smll incsnea* of 473interionsrnd 16?sverciirar T'blc 1 Lo.alizdioiald ftequcn.v

pl.ud[s, lung Lms inrcdions(pncunonii brcnchiris,

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riked i!hfibicc (6096) maletorcnllchrioirrbouorT:rrft.dirsiosisis

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