A R T I C L E. Clinical Characteristics of IDDM in Hispanics and Non-Hispanic. Whites. Little evidence of heterogeneity by ethnicity. JILL N. KOSTRABA, PHD.
O
R
I
G
I
N
A
L
A R T I C L E
C
linical and metabolic studies of IDDM in the US black population have detected heterogeneity in the expression of diabetes, which has been attributed to the misclassification of early-onset NIDDM as IDDM in some cases (1). The increased prevalence of NIDDM in US blacks compared with US whites (2) may contribute to classification errors. Hispanic Americans also have an JILL N. KOSTRABA, PHD H. PETER CHASE, MD increased incidence (3) and prevalence KAREN J. CRUICKSHANKS, PHD GEORGEANNAJ. KLINGENSMITH, MD (4) of NIDDM compared with nonELIZABETH C. GAY, MA TERRI G. NEVILLE, BS Hispanic whites. However, because no RICHARD F. HAMMAN, MD, DRPH JANET LAWLER-HEAVNER, MSPH studies characterizing IDDM in the Hispanic population have been conducted, OBJECTIVE— To compare the clinical characteristics of IDDM in HD and NHWD it is unknown whether diabetes heterogeneity, similar to that seen in blacks, subjects in order to evaluate potential heterogeneity of IDDM by ethnicity. occurs in Hispanic Americans. Our iniRESEARCH DESIGN AND METHODS— HD subjects (n = 73) and NHWD tial report on ethnic differences in IDDM subjects (n = 97) were recruited from the Colorado IDDM Registry. The registry incidence in Colorado demonstrated that included individuals who were Colorado residents,
