Clinical Outcome and Predictive Factors in the ...
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Original Paper Received: June 25, 2015 Accepted after revision: November 22, 2015 Published online: January 16, 2016
Clinical Outcome and Predictive Factors in the Response to Splenectomy in Elderly Patients with Primary Immune Thrombocytopenia: A Multicenter Retrospective Study Young Hoon Park a Hyeon Gyu Yi a Chul Soo Kim a Junshik Hong b Jinny Park b Jae Hoon Lee b Ho Young Kim c Hyo Jung Kim c Dae Young Zang c Se Hyung Kim d Seong Kyu Park d Dae Sik Hong d Guk Jin Lee e Jong-Youl Jin e on behalf of Gyeonggi/Incheon Branch, The Korean Society of Hematology
Departments of Internal Medicine at a Inha University Hospital, Inha University School of Medicine, and b Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, c Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, and d Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Soonchunhyang University, and e Department of Internal Medicine, Bucheon St. Mary’s Hospital, The Catholic University of Korea, Bucheon, Korea
Abstract Background: Because many physicians seem reluctant to recommend splenectomy for elderly patients with immune thrombocytopenia (ITP), we investigated the safety and efficacy of splenectomy and the predictive factors for response in these patients. Methods: 184 patients with primary ITP were retrospectively analyzed based on age at splenectomy: an elderly group (≥60 years, n = 52) and a younger group (
