(1980b) using HeLa, FS4 (normal human fibroblasts) and SK-OS-10 (osteogenic sarcoma) cells reported human IFN-y to be a more potent antiproliferative agent ...
J. gen. ViroL (t983), 64,
1743
1743-1748. Printed in Great Britain
Key words: human IFNs/antiproliJerative effects~induced proteins~differential responsiveness
Comparative Antiproliferative Efficacies of Human ~ and ? Interferons By B E R I S H Y. R U B I N , * V A I T H I L I N G A M W I L L I A M A. M A R T I M U C C I
S E K A R AND
Memorial Sloan-Kettering Cancer Center, N e w York, N e w York 10021, U.S.A. (Accepted 25 February 1983)
SUMMARY
The cell growth inhibitory efficacies of preparations of human ct and 7 interferons (IFNs) have been tested on a variety of human cell lines. Human IFN-~ was found to be more effective at inhibiting the growth of HeLa and U-amnion cells than was human IFN
