1761 techwatch Creating A. High-Performance System. For Comparative Effectiveness. Research ... Harold C. Sox data &
at the intersection of he alth, he alth care, and polic y
October 2010
Vol. 29
No. 10
healthaffairs.org
Comparative Effectiveness Research from the editor-in-chief 1756
Comparative Effectiveness: Coherent Health Care At Last? Susan Dentzer
entry point 1757
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The Political Fight Over Comparative Effectiveness Research John K. Iglehart
shaping the national strategy 1761
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techwatch Creating A High-Performance System For Comparative Effectiveness Research Lynn M. Etheredge An Evaluation Of Recent Federal Spending On Comparative Effectiveness Research: Priorities, Gaps, And Next Steps Joshua S. Benner, Marisa R. Morrison, Erin K. Karnes, S. Lawrence Kocot, and Mark McClellan
Health Reform's Tortuous Route To The Patient-Centered Outcomes Research Institute Kavita Patel techwatch Comparative Effectiveness And Personalized Medicine: Evolving Together Or Apart? Robert Epstein and J. Russell Teagarden
data & methods 1812
A Flexible Approach To Evidentiary Standards For Comparative Effectiveness Research Louis P. Garrison, Peter J. Neumann, Paul Radensky, and Sheila D. Walcoff
1818
Why Observational Studies Should Be Among The Tools Used In Comparative Effectiveness Research Nancy A. Dreyer, Sean R. Tunis, Marc Berger, Dan Ollendorf, Pattra Mattox, and Richard Gliklich
costs & value 1788
Comparative Effectiveness Research: From Clinical Information To Economic Incentives James C. Robinson
1796
techwatch How Medicare Could Use Comparative Effectiveness Research In Deciding On New Coverage And Reimbursement Steven D. Pearson and Peter B. Bach
1826
The Critical Role Of Observational Evidence In Comparative Effectiveness Research Rachael L. Fleurence, Huseyin Naci, and Jeroen P. Jansen
1805
analysis & commentary The Role Of Costs In Comparative Effectiveness Research Alan M. Garber and Harold C. Sox
1834
How Best To Engage Patients, Doctors, And Other Stakeholders In Designing Comparative Effectiveness Studies Ari Hoffman, Russ Montgomery, Wade Aubry, and Sean R. Tunis Continued on page 1752
Health Affairs is a multidisciplinary, peer-reviewed journal dedicated to the serious exploration of domestic and international health policy issues. Health Affairs (ISSN: 0278-2715, electronic ISSN: 1544-5208) is published monthly by Project HOPE, 7500 Old Georgetown Road, Suite 600, Bethesda, MD 20814-6133. ©2010 by Project HOPE — The People-to-People Health Foundation, Inc. Periodicals-class postage paid at Bethesda, Maryland, and at additional mailing offices. online access Full online archives of all papers published in Health Affairs since 1981 appear at www.healthaffairs.org. Web First papers appear online ahead of print. Health Affairs’ website is produced in conjunction with Stanford University’s HighWire Press. postmaster Send Change of Address to Health Affairs, P.O. Box 148, Congers, NY 10920-1048.
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techwatch Designing Comparative Effectiveness Research On Prescription Drugs: Lessons From The Clinical Trial Literature Dave A. Chokshi, Jerry Avorn, and Aaron S. Kesselheim
entry point
tailoring research 1849
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Special Challenges In Comparative Effectiveness Research On Children’s And Adolescents’ Health Lisa A. Simpson, Laura Peterson, Carole M. Lannon, Sharon B. Murphy, Clifford Goodman, Zhaoxia Ren, and Anne Zajicek analysis & commentary Comparative Effectiveness Research In Mental Health: An Advocate's Perspective David L. Shern, Kirsten K. Beronio, Chin-Chin I. Minniear, and Sarah M. Steverman
patients & other stakeholders
Ellen Sigal, president of Friends of Cancer Research and a member of the PatientCentered Outcomes Research Institute’s governing board, says the cancer community supported comparative effectiveness research after advocates realized that it could increase understanding of which therapies work best for individual patients.
1901
analysis & commentary Moving Comparative Effectiveness Research Into Practice: Implementation Science And The Role Of Academic Medicine Ann C. Bonham and Mildred Z. Solomon
1906
The Veterans Affairs Experience: Comparative Effectiveness Research In A Large Health System David Atkins, Joel Kupersmith, and Seth Eisen
1913
people & places Veterans Health Administration: Three Decades Of Comparative Effectiveness Research
1914
analysis & commentary The Case For A National Patient Library Jeffrey C. Lerner, Daniel M. Fox, Sheryl B. Ruzek, and Gail E. Shearer
web first
1863
Adding The Patient Perspective To Comparative Effectiveness Research Albert W. Wu, Claire Snyder, Carolyn M. Clancy, and Donald M. Steinwachs
1872
The Public Wants Information, Not Board Mandates, From Comparative Effectiveness Research Alan S. Gerber, Eric M. Patashnik, David Doherty, and Conor Dowling
1882
A National Survey Reveals Public Skepticism About Research-Based Treatment Guidelines Alan S. Gerber, Eric M. Patashnik, David Doherty, and Conor Dowling
1885
analysis & commentary A Patient Advocate’s Perspective On PatientCentered Comparative Effectiveness Research Tony Coelho
translating the results 1891
1920
Who And Where Are The Children Yet To Enroll In Medicaid And The Children’s Health Insurance Program? Genevieve M. Kenney, Victoria Lynch, Allison Cook, and Samantha Phong
1930
analysis & commentary Rising To The Challenge: Tools For Enrolling Eligible Children In Health Coverage Kathleen Sebelius
‘Bench To Behavior’: Translating Comparative Effectiveness Research Into Improved Clinical Practice Jerry Avorn and Michael Fischer Continued on page 1753
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Vol. 29 No. 10 healthaffairs.org
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1933
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National Health Spending Projections: The Estimated Impact Of Reform Through 2019 Andrea M. Sisko, Christopher J. Truffer, Sean P. Keehan, John A. Poisal, M. Kent Clemens, and Andrew J. Madison Health Benefits In 2010: Premiums Rise Modestly, Workers Pay More Toward Coverage Gary Claxton, Bianca DiJulio, Heidi Whitmore, Jeremy D. Pickreign, Megan McHugh, Awo Osei-Anto, and Benjamin Finder A Progress Report On Electronic Health Records In U.S. Hospitals Ashish K. Jha, Catherine M. DesRoches, Peter D. Kralovec, and Maulik S. Joshi
1972
Why I Don't Get Mammograms Veneta Masson
Providers Of Anesthesia: Does Quality Vary? Alexander A. Hannenberg
1972
The Emotional Work Of Dealing With Patients Ann Sinclair and Donald Nease
1973
Communication Goes Two Ways Thomas P. Sellers
1973
Physicians’ Communication Skills: The Authors Respond Wendy Levinson, Cara Lesser, and Ronald Epstein
1973
1974
grantwatch 1961
Helping Nursing Homes Prepare For Disasters Kathryn Hyer, Lisa M. Brown, LuMarie Polivka-West, and Amy Berman
Anesthesia Training: Another View Rebecca Patchin
1972
narrative matters 1958
health policy briefs
letters
1975
Continued Education Needed As Reforms Are Implemented Philip Pollner and Nancy Wooten Reform Efforts Continue: The Author Replies Theda Skocpol
Health Policy Briefs provide clear, accessible overviews of timely and important health policy topics. The peer-reviewed briefs explore competing arguments and point out relevant research. Health Policy Briefs are available online and produced by Health Affairs through a grant from the Robert Wood Johnson Foundation. Sign up for free policy briefs at http://www.healthaffairs.org/ healthpolicybriefs.
‘Meaningful Use’ Of Electronic Health Records August 24, 2010 Patient-Centered Medical Homes September 14, 2010 Standards & Certification Of Electronic Health Records September 2010 Comparative Effectiveness Research October 2010
Instructions To Authors
Illustration by Brett Ryder
book reviews 1966
Is There A Lack Of Ethical Integrity In Drug Clinical Trials? Trudo Lemmens
1967
The Challenge Of Deriving Health Policy Lessons From Abroad Patricia Pittman
1969
BookMarks
Narrative Matters A nurse practitioner tells why she and many experts believe that most regular screening mammograms don’t save lives but instead give rise to false fears and unneeded biopsies.
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