Kashin-Beck disease, osteoarthritis and rheumatoid arthritis. Wenhong Wu#1, Awen He#1, Yan Wen1, Xiao Xiao1, Jingcan Hao1, Feng. Zhang1*, Xiong Guo1* ...
Comparison of microRNA expression profiles of Kashin-Beck disease, osteoarthritis and rheumatoid arthritis Wenhong Wu#1 , Awen He#1, Yan Wen1, Xiao Xiao1, Jingcan Hao1, Feng Zhang1*, Xiong Guo1*
Table S1. List of target genes of miRNAs differently expressed in KBD vs. Control Gene Name PDHA1 GUCA1A CYP1A1 RHO CD4 CD79B
Genebank_ID NM_000284 NM_000409 NM_000499 NM_000539 NM_000616 NM_000626
CACNA1C
NM_000719
CHRM1 CHRNB2 CYP4A11 C18ORF1
NM_000738 NM_000748 NM_000778 NM_001003674
BUB3
NM_001007793
C1ORF130 DCTD SORBS3 AP2M1 CBLN3 NRF1 LRRCC1 MED24 UNC13A HDGF LY6E SPRED2 GFI1B C8ORF40 RCC2
NM_001010980 NM_001012732 NM_001018003 NM_001025205 NM_001039771 NM_001040110 NM_001077501 NM_001079518 NM_001080421 NM_001126050 NM_001127213 NM_001128210 NM_001135031 NM_001135674 NM_001136204
SLCO2B1
NM_001145211
PFKFB3 SEMA7A LEPRE1 APAF1
NM_001145443 NM_001146029 NM_001146289 NM_001160
PLEKHA4
NM_001161354
CHAD INPPL1 BSG CUX1 EYA3 NTSR1 PIGR RBMS1 SELP
NM_001267 NM_001567 NM_001728 NM_001913 NM_001990 NM_002531 NM_002644 NM_002897 NM_003005
Gene Description pyruvate dehydrogenase (lipoamide) alpha 1 guanylate cyclase activator 1A (retina) cytochrome P450, family 1, subfamily A, polypeptide 1 rhodopsin CD4 molecule CD79b molecule, immunoglobulin-associated beta calcium channel, voltage-dependent, L type, alpha 1C subunit cholinergic receptor, muscarinic 1 cholinergic receptor, nicotinic, beta 2 (neuronal) cytochrome P450, family 4, subfamily A, polypeptide 11 chromosome 18 open reading frame 1 budding uninhibited by benzimidazoles 3 homolog (yeast) chromosome 1 open reading frame 130 dCMP deaminase sorbin and SH3 domain containing 3 adaptor-related protein complex 2, mu 1 subunit cerebellin 3 precursor nuclear respiratory factor 1 leucine rich repeat and coiled-coil domain containing 1 mediator complex subunit 24 unc-13 homolog A hepatoma-derived growth factor lymphocyte antigen 6 complex, locus E sprouty-related, EVH1 domain containing 2 growth factor independent 1B transcription repressor chromosome 8 open reading frame 40 regulator of chromosome condensation 2 solute carrier organic anion transporter family, member 2B1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 semaphorin 7A, GPI membrane anchor leucine proline-enriched proteoglycan (leprecan) 1 apoptotic peptidase activating factor 1 pleckstrin homology domain containing, family A, member 4 chondroadherin inositol polyphosphate phosphatase-like 1 basigin (Ok blood group) cut-like homeobox 1 eyes absent homolog 3 (Drosophila) neurotensin receptor 1 (high affinity) polymeric immunoglobulin receptor RNA binding motif, single stranded interacting protein 1 selectin P (granule membrane protein 140kDa, antigen
SYT5 VIPR2 CLIP2 WNT8B FZD5 PDXK RGS11 PHOX2B ORC1L SYT7
NM_003180 NM_003382 NM_003388 NM_003393 NM_003468 NM_003681 NM_003834 NM_003924 NM_004153 NM_004200
SLC22A13
NM_004256
ARL3 PTTG1IP FUT8 NEB SF1 AP3B2 PCSK7 RAB36 ACTN4 PRSS16 APC2 SLC1A7 LAPTM5 METAP2 C14ORF1 AKAP10 HNRNPH3
NM_004311 NM_004339 NM_004480 NM_004543 NM_004630 NM_004644 NM_004716 NM_004914 NM_004924 NM_005865 NM_005883 NM_006671 NM_006762 NM_006838 NM_007176 NM_007202 NM_012207
KIN
NM_012311
SPDEF C16ORF5 MEA1 LRRC14 SIPA1L3 NUP188 DCAF12 SOSTDC1 CHD5 LDLRAP1 ZNF589 SGK2 HOXC13 TMEM104 MKS1 PNPO
NM_012391 NM_013399 NM_014623 NM_014665 NM_015073 NM_015354 NM_015397 NM_015464 NM_015557 NM_015627 NM_016089 NM_016276 NM_017410 NM_017728 NM_017777 NM_018129
CD62) synaptotagmin V vasoactive intestinal peptide receptor 2 CAP-GLY domain containing linker protein 2 wingless-type MMTV integration site family, member 8B frizzled homolog 5 (Drosophila) pyridoxal (pyridoxine, vitamin B6) kinase regulator of G-protein signaling 11 paired-like homeobox 2b origin recognition complex, subunit 1-like (yeast) synaptotagmin XVII; synaptotagmin VII solute carrier family 22 (organic anion transporter), member 13 ADP-ribosylation factor-like 3 pituitary tumor-transforming 1 interacting protein fucosyltransferase 8 (alpha (1,6) fucosyltransferase) nebulin splicing factor 1 adaptor-related protein complex 3, beta 2 subunit proprotein convertase subtilisin/kexin type 7 RAB36, member RAS oncogene family actinin, alpha 4 protease, serine, 16 (thymus) adenomatosis polyposis coli 2 solute carrier family 1 (glutamate transporter), member 7 lysosomal multispanning membrane protein 5 methionyl aminopeptidase 2 chromosome 14 open reading frame 1 A kinase (PRKA) anchor protein 10 heterogeneous nuclear ribonucleoprotein H3 (2H9) KIN, antigenic determinant of recA protein homolog (mouse) SAM pointed domain containing ets transcription factor chromosome 16 open reading frame 5 male-enhanced antigen 1 leucine rich repeat containing 14 signal-induced proliferation-associated 1 like 3 nucleoporin 188kDa WD repeat domain 40A sclerostin domain containing 1 chromodomain helicase DNA binding protein 5 low density lipoprotein receptor adaptor protein 1 zinc finger protein 589 serum/glucocorticoid regulated kinase 2 homeobox C13 transmembrane protein 104 Meckel syndrome, type 1 pyridoxamine 5'-phosphate oxidase
USP40 SH3GLB2
NM_018218 NM_020145
PITPNM2
NM_020845
KAT2A ALOXE3 MS4A1 HIF3A KLHL25 FAM160B2 C8ORF33
NM_021078 NM_021628 NM_021950 NM_022462 NM_022480 NM_022749 NM_023080
GDAP1L1
NM_024034
CAMKV ABHD8 MAP7D3 FAM49A KLF16 FGFBP2 MXRA8 LZTS2 CAPS2 FHDC1 CCDC97 APOA5 SMC1B PAQR4 C19ORF25 GJB4 C19ORF21 C17ORF78 ZCCHC12 ARNT BCDIN3D SPATA12 BCL9L VSX2 P4HA3 UBL4B TEX19
NM_024046 NM_024527 NM_024597 NM_030797 NM_031918 NM_031950 NM_032348 NM_032429 NM_032606 NM_033393 NM_052848 NM_052968 NM_148674 NM_152341 NM_152482 NM_153212 NM_173481 NM_173625 NM_173798 NM_178427 NM_181708 NM_181727 NM_182557 NM_182894 NM_182904 NM_203412 NM_207459
ubiquitin specific peptidase 40 SH3-domain GRB2-like endophilin B2 phosphatidylinositol transfer protein, membrane-associated 2 K(lysine) acetyltransferase 2A arachidonate lipoxygenase 3 membrane-spanning 4-domains, subfamily A, member 1 hypoxia inducible factor 3, alpha subunit kelch-like 25 (Drosophila) family with sequence similarity 160, member B2 chromosome 8 open reading frame 33 ganglioside-induced differentiation-associated protein 1-like 1 CaM kinase-like vesicle-associated abhydrolase domain containing 8 MAP7 domain containing 3 family with sequence similarity 49, member A Kruppel-like factor 16 fibroblast growth factor binding protein 2 matrix-remodelling associated 8 leucine zipper, putative tumor suppressor 2 calcyphosine 2 FH2 domain containing 1 coiled-coil domain containing 97 apolipoprotein A-V structural maintenance of chromosomes 1B progestin and adipoQ receptor family member IV chromosome 19 open reading frame 25 gap junction protein, beta 4, 30.3kDa chromosome 19 open reading frame 21 chromosome 17 open reading frame 78 zinc finger, CCHC domain containing 12 aryl hydrocarbon receptor nuclear translocator BCDIN3 domain containing spermatogenesis associated 12 B-cell CLL/lymphoma 9-like visual system homeobox 2 prolyl 4-hydroxylase, alpha polypeptide III ubiquitin-like 4B testis expressed 19
