Active substances. AOEL mg/kg b.w./d. Content of active substance. Category. Type of crops. Pirimicarb. Thiram. Chlorpyrifos-methyl. Mancozeb. Chlorpyrifos.
!"#$%&'()*$+&,-$./0$1234567879:1;3?%@AB $?>CBDDEFG$HI$H$A>>D$J> $A.B$BK%>I@ B$ HIIBII?BFA$>J$>%B HA> I$@IEFG$JH@DAL$HG E=@DA@ HD$ %BIAE=ECB$I% HLEFG$BM@E%?BFA !"#$%&'()*!+,*-1*.&'!/#0(&1-(2$!+,*(1.&3($%40(&'#$#,-),*(1.&5(0&67&892+-:*-1 .&59,%40(& ;!+!$4%(!+(:*(1.&?$%9$&=!24)@.&=$A#B!$A&C!$9:D!+,*-@.& 4,A($2&E!>!+0-:*-@ 1
Department of Toxicology and Risk Assessment, National Institute of Public Health -National Institute of Hygiene, Warsaw, Poland 2 Research Institute of Pomology and Floriculture, Skierniewice, Poland
HNIA H=A N&",0O!P'QR$Faulty but still operating agricultural pesticide sprayers may pose an unacceptable health risk for operators. The computerized models designed to calculate exposure and risk for pesticide sprayers used as an aid in the evaluation and further authorisation of plant protection products may be applied also to assess a health risk for operators when faulty sprayers are used. >STU")/VUR$To evaluate the impact of different exposure scenarios on the health risk for the operators using faulty agricultural spraying equipment by means of computer modelling. ?&)UO/&-$&'Q$WU)X!Q(R$The exposure modelling was performed for 15 pesticides (5 insecticides, 7 fungicides and 3 herbicides). The critical parameter, -7#. toxicological end-point, on which the risk assessment was based was the no observable adverse effect level (NOAEL). This enabled risk to be estimated under various exposure conditions such as pesticide concentration in the plant protection product and type of the sprayed crop as well as the number of treatments. Computer modelling was based on the UK POEM model including determination of the acceptable operator exposure level (AOEL). Thus the degree of operator exposure could be defined during pesticide treatment whether or not personal protection equipment had been employed by individuals. Data used for computer modelling was obtained from simulated, pesticide substitute treatments using variously damaged knapsack sprayers. These substitute preparations consisted of markers that allowed computer simulations to be made, analogous to real-life exposure situations, in a dose dependent fashion. Exposures were estimated according to operator dosimetry exposure under ‘field’ conditions for low level, medium and high target field crops. U(P-)(R$The exposure modelling in the high target field crops demonstrated exceedance of the AOEL in all simulated treat2%3'!7)-%-!CDEEFG!?-.39!;)2)9%;!-1&):%&-!.&&%-1%7'.H%!#4!'B%!':1%!#4!;)2)9%!#&!.4!.3;.H.;?)8!1&#'%7'.H%!2%)-?&%-!B);!$%%3! );#1'%;!#&!3#'I!J#&!8#,!8%H%8!)3;!2%;.?2!4.%8;!7-!%67%%;)37%-!&)39%;!$%',%%3!KE!L!MEF!7)-%-I =!'"-P(/!'(R$The computer modelling may be considered as an practical tool for the hazard assessment when the faulty agricultural sprayers are used. It also may be applied for programming the quality checks and maintenance systems of this equipment. Key words:&#FG!,9$#&H!2#I,.&!G#$(%!$.&#FG!,9$#&%!&G#,%-:-2#,.&,G$(4#$,.&:!HG9%#$&H!2#II-0B.&!::9G(%-!0(I&#FG!,9$#
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perator exposure assessment conducted for sprayers in three different technical states. The Research Institute of Pomology, Skierniewice, Poland 2010 (in Polish).
276
!"#$%&'()&*+"#!",*$-.'()&$+"/!"#0.0)*%)&$"01"$2!
7. Guidance for the setting and application of acceptable operator exposure levels (AOEL). SANCO 7531 - rev. 10, 7 July 2006, App 1. 8.& =U$(I:A4*&67.&6!,%*(&=7.&892+-:*-&5767.&P%$9:-),*-&J7: Guide in terminology: Toxicology, Food Safety, Public Health, Risk Assessment. Ed. 892+-:*-& 5767, National Institute of Public Health-National Institute of Hygiene, Warsaw 2013 (in Polish). 9.& E(42#0& 637.& ;!$%!0& 37S7.& C($:#4& C7.& V,%"4#& M7.& W(02-&J7J7.&'$#-%0#$&57P7S7.&1#I,D
