The 3rd International Conference of the Arab Society for Medical Research Under the theme of
Medical Research in the Arab World "Modes of Collaboration and Development" Under the Patronage of H. E.
Mr. Amr Moussa Secretary General of the League of Arab States
Prof. Dr. Abduelkabir El-Fakhri Secretary General of People's Committee for Higher Education and Scientific Research - Libya
Conference Chairmen Prof. Dr. Ashraf Shaalan President of the Arab Society for Medical Research President of the NRC-Egypt
Dr. Abdul-Fatah Gbaj President of National Medical Research Center - Libya
Conference Co-Chairman Prof. Dr. Karam Mahdy General Secretary Prof. Dr. Azza Abd El-Shaheed October, 12 - 14th, 2010 National Medical Research Center Al-Zawia - Libya
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Contents Welcome message Organizing Committee Main Topics Invited Gusts General Information (Conference Venue, Halls, Badges) Conference At Glance Conference Program October 12th 2010 October 13th 2010 October 14th 2010
Conference Abstracts Plenary I Pediatrics I Biophysics Microbiology and Parasitology Plenary II Reproductive and Fetal Medicine Pediatric Nutrition Natural Products Biochemistry Pediatrics II Public Health I Pharmacology Internal Medicine Child Health Surgery & Stem cell Clinical Pathology and Molecular Genetics Public Health II Hospital Acquired Infection Environmental & Occupational Medicine Posters
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5 6 7 8 9 10 11 13 19 27 39 41 45 51 57 63 67 73 79 85 91 97 103 109 115 121 127 133 139 145 151
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Welcome Message
Dear colleagues It is the greatest pleasure to welcome you to the 3rd International Conference of the Arab Society for Medical Research that held in Al-Zawia City - Libya at the National Medical Research Center. The main theme of the meeting this year is Modes of Collaboration and Development; the scopes of interest have been extended to include the most recent advances in the different domains of the medical sciences. The Arab society is aiming at faster cooperation and networking of medical schools of Arab countries in order to advance medical research globally. The conference program includes different recent research in most of medical fields in Arab World, in addition to some advanced countries such as Germany and Japan. We hope all participants will enjoy the pleasure of warm Libyan hospitality and culture. We assure you that this meeting will represent a memorable addition to our scientific knowledge. Chairman of the Arab Society for Medical Research Chairman of National Research Centre Conference Chairman Prof. Dr. Ashraf Shaalan
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Organizing Committee General Co-ordinators Prof. Abdel Razik Farrag Prof. Adel Ashour
Members
Mr. Waled Alshatte
Mr. Ali Mahjobe
Mr. Adel Abosora
Mr. Abdulrazak Kamar
Mr. Ashour Fazane
Eng. Imen Kelani
Eng. Hamza Alaswad
Eng. Hitem Algariani
Mrs. Mariam Kenz
Mr. Moataz Hassan
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Main Topics • • • • • • • • • • • • • • • • • • • • • •
Pediatrics and Child Health Endemic Diseases Microbiology and Parasitology Gynacology, Obstetrics and Fetal Medicine Reproductive Medicine Bilogical Anthropology Pharmacology Bioactive Natural Products Surgery & Stem cell Oncology Internal Medicine Public Health Clinical Pathology and Molecular Genetics Biophysics Medical Biochemistry Environmental and Occupational Medicine Physiotherapy Nursing Zonotic and Parasitic Diseases Complementary Medicine Dermatology Nutritional Disorders
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Invited Gusts Prof. Dr. Thomas Simmet (Germany) University of Ulm Institute of Pharmacology, Toxicology & Natural Products Department of Pharmacology of Natural Products & Clinical Pharmacology Helmholtzstr, 20 D-89081 Ulm, Germany Prof. Dr. Masanori Yoshioka (Japan) Faculty of Pharmaceutical Sciences Setsunan University 45-1, Nagaotogecho, Hirakata Osaka, 573-0101, Japan Prof. Dr. Nasr Eldin Ahmed Eltantawy World Health Organization (WHO)
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General Information Date: October 12 - 14, 2010 Country: Libya City: Al-Zawia Venue: National Medical Research Center Conference Halls: Main Hall, Halls (1, 2, 3) Registration: At the registration desk from 9:00 AM till 10:00 AM on Tuesday Language: Scientific activities will be in English & Arabic Data Show & Slides: Please submit your CD/slides to the slide delivery Hall at least one hour before the presentation time. Posters: The posters should be placed in the Hall in which session will be hold Badges: Red Green Yellow Blue
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Chairpersons Organizing Committee Speakers/Posters Attendants
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Time 09:00 - 10:00
October 12th 2010
Conference at Glance Date
10:00 - 11:00 11:00 - 12:00 12:00 - 01:00
October 13th2010
Hall 1
Pediatrics I
02:30 - 03:30
10:00 - 11:30 11:30-12:30 12:30 - 02:00 02:00 – 03:00 09:00 - 10:30 10:30 - 12:00 12:00 – 01:00 01:00 - 02:30 02:30 – 03:00 03:00 – 04:00
Hall 2
Hall 3
Coffee Break
01:00 - 02:30
09:00 - 10:00
October 14th2010
Main Hall Registration Opening Ceremony Plenary 1
Biophysics
Microbiology and Parasitology
Lunch Social Events Plenary II Reproductive & Fetal Medicine
Pediatric Nutrition
Coffee Break Pediatrics II Lunch Social Events Pharmacology Internal Medicine Clinical Pathology and Surgery & Stem cell Molecular Genetics Coffee Break Hospital Acquired Environmental & Infection Occupational Medicine Closing Ceremony Lunch Biochemistry
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Natural Products Public Health I
Child Health Public Health II
Posters
Conference Program
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October 12th 2010 09:00 - 10:00
09:00-11:00 Main Hall Registration Opening Ceremony Welcome Addresses و ﺱ/• آ ﻝ اﻝ ا ا م ا ول ا H.E. Mr. Amr Moussa Secretary General of the League of Arab State
10:00 – 11:00
اﻝ اﻝ ى/• ﻝ اﺱ ذ اﻝآر ا ا ا ا وا ا هی ا Prof. Dr. Abduelkabir El-Fakhri Secretary General of People's Committee for Higher Education and Scientific Research – Libya اﻝ"ى اﻝ ﺏ اﻝ/• اﻝاء ﺝ ! ا اوی# (' ! م ا& دات ا ا Brigade. Almahde Alarabe Abdulhafed General Coordinator of the Social Popular Leadership in Al – Zawia City زى$ د اﻝ/ • ﻝ اﺱ ذ ا ا ا ا * وا) هی ا Sir. Mohamed Alhegaze Secretary General of Health and Environment – Libya أ'ف ' *ن/• اﺱ ذ اﻝآر +& اآ ا- ورﺉ0ث ا+ ا ا-رﺉ (ﺕ5 ا-ث – * )رﺉ+ Prof. Dr. Ashraf Saalan President of the Arab Society for Medical Research, President of National Research Centre, Cairo, Egypt (Conference Chairman)
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October 12th
11:00 - 12:00 Plenary I The Main Hall
Chairs: Prof.
Ashraf Shaalan Abdul-Fatah Gbaj Karam Mahdy Azza Abdel Shaheed
11:00 – 11:25
Pandemic Influenza: Global and Regional Update Nasr Eldin Ahmed Eltantawy
11:25 – 11:50
Influenza Viruses: The 21th Century Threat Mohamed Ahmed Ahmed Ali
11:50– 12:00
Discussion
12:00 – 01:00
Coffee Break
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October 12th
01:00 - 02:30 Pediatrics I
Chairs: Prof.
01:00 - 01:15
Hall 1 Enas Abdel Hameed Nayera Hassan Aamir Jalal Bone Metabolism Alteration in Children with Type 1 Diabetes Mellitus Enas R Abdel Hameed
01:15 - 01:30
Pulmonary Function Changes after a Rehabilitation Program to Asthmatic Children Hala Goda Elnady
01:30 - 01:45
Differential Elevation of Matrix Metalloproteinases 1 and 2 in Pediatrics Chronic Liver Diseases Azza Abd El-Shaheed
01:45 - 02:00
A Study of the Etiology, Risk Factors, Clinical Features and Pitfalls in Management of Newly Diagnosed Diabetic Children and Adolescents Hala M. Koura
02:00 - 02:15
Anticipating Mechanical Ventilation in Children with Guillain–Barre Syndrome and Improving Outcome of the Illness Muhi K. Al - janabi
02:15 - 02:30
Discussion
02:30 - 03:30
Lunch Social Events
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October 12th
01:00 - 02:30 Biophysics
Chairs: Prof.
01:00 - 01:15
Hall 2 Masanori Yoshioka Safaa Khalil Riad Ababneh Use of the FT-IR spectroscopy in Determination of the Mucopoly-saccharidoses Types Safaa K. H. Khalil
01:15 - 01:30
Platform by Mass Spectrometry of Transthyretin as a Real Model Protein for Elucidation for Amyloidoses Masanori Yoshioka
01:30 - 01:45
Use of Fe3O4 Nanoparticles as Contrast Agent in Magnetic Resonance Imaging Marwa Yousef Al-Nakow Freski
01:45 - 02:00
193 Nm Arf Excimer Laser Induced Aqueous Humor Changes In Rabbit´S Eyes Abdelkawi, S. A
02:00 - 02:15
Fat-Water Separation in Dynamic Objects Using a Temporal Domain Approach Riad Ababneh
02:15 - 02:30
Discussion
02:30 - 03:30
Lunch Social Events
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October 12th
01:00 - 02:30 Microbiology and Parasitology Hall 3
Chairs: Prof.
Ahmad Shaban Elmeya Safar Salam Al-Garsade
01:00 - 01:15
Involvement of the Eye by Acanthamoeba: Review Article Elmeya H Safar
01:15 - 01:30
Synthesis and Evaluation of Antimicrobial Activity of Some New Schiff Base Derivatives Salah B. Mohamed
01:30 - 01:45
Prevalence of Intestinal Microsporidiosis in Citizens of Greater Cairo, Egypt Ahmad Z. Al-Herrawy
01:45 - 02:00
Comparison between Membrane Filter and PCR Methods for Detection of Coliform, E. coli and Salmonella in Drinking Water Shaban A. M
02:00 - 02:15
The Effect of Sodium Dichloroisocyanurate on Toxocara Canis Eggs Sonia Allam
02:15 - 02:30
Discussion
02:30 - 03:30
Lunch Social Events
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October 13th
09:00 - 10:00 Plenary II
Chairs: Prof.
09:00 - 09:25
Main Hall Ashraf Shaalan Abdul-Fatah Gbaj Karam Mahdy Azza Abdel Shaheed Initial Trauma Management Mahsoub M. Amin
09:25 - 09:50
Towards a Strategy in the Arab World for Better Maternal-Fetal Health Care Khaled R Gaber
09:50 - 10:00
Discussion
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October 13th
10:00 - 11:30 Reproductive and Fetal Medicine
Chairs: Prof.
10:00- 10:15
Hall 1 Khaled Gaber Osama Azmy Hayat Gommaa Maternal Vitamin B12 and the Risk of Fetal Neural Tube Defects in Egyptian Patients Khaled R. Gaber
10:15- 10:30
A Novel Endometriosis Inducing Factor in Women with Endometriosis Osama Azmy
10:30- 10:45
Prevelance of Cesarean Section and it’s Related Factors in Subrata Hospital Libya Mawia Mohamed M. Besht
10:45- 11:00
Assessment of Common Types of Vaginal Infections among Women Attending Gynecology Clinics at El-Manial University Hospital: A proposed Plan of Action Amel Dawod Kamel
11:00- 11:15
The Effect of Pelvic Floor Muscle Training on Improving its Strength among Women with Stress Urinary Incontinence Hayat I. Gommaa
11:15 - 11:30 11:30 - 12:30
Discussion Coffee Break
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October 13th
10:00 - 11:30 Pediatric Nutrition
Chairs: Prof.
10:00- 10:15
Hall 2 Azza Abd El-Shaheed Muhi Al - janabi Belgasem Algerbe Prevalence of Metabolic Syndrome among Obese Egyptian Children and Adolescents Nayera E. Hassan
10:15- 10:30
Nutritional Assessment of Egyptian Children Sahar A. El Masry
10:30- 10:45
Micronutrient Status Cerebral Palsy
in
Children
with
Suzette Ibrahim Helal
10:45- 11:00
Nutritional and Health Status of a Random Sample of Benghazi Adolescents -Global School Health Survey (GSHS) Suneetha Epuru
11:00- 11:15
Osteoporosis Knowledge, Beliefs, and Behaviors among Egyptian Female Students S.A.Wahba
11:15 - 11:30
Discussion
11:30 - 12:30
Coffee Break
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October 13th
10:00 - 11:30 Natural Products Hall 3
Chairs: Prof.
Fathe Alsharef Hanaa H. Ahmed Thomas Simmet
10:00 - 10:20
The Lipid Lowering and Antioxidant Effect of Dates (Phoenix Dactylifera-L) from Libya, on Hypercholesterolemic Induced Rabbit Nawal Salem Ab. Hasan
10:20 - 10:40
Herbal Product's Antibacterial Effect: A Comparative Study Saleh A. Mursi
10:40 - 11:00
Urea Lowering Effect of Acacia Gum Supplementation of Low Protein Diet in Patients with Symptomatic Uremia Aamir Jalal Al Mosawi
11:00 - 10:20
Antihepatotoxic Activity of Fennel (Foeniculum Vulgare Mill.) Essential Oil against Chlorpyrifos-Induced Liver Injury in Rats Amal A. Refaie
11:20 - 11:30 11:30 –12:30
Discussion Coffee Break
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October 13th
12:30 - 02:00 Biochemistry Hall 1
Chairs: Prof.
Karam Mahdy Abdel Razik Farrag Mohamed Ahmed Ali
12:30 - 12:50
Prevalence of HBsAg in Population of Northwestern Libya Maisoun Omar Ferjani
12:50 - 01:10
Synthesis and Biological Evaluation of Anticancer Compounds Using DNA, Thymidine Phosphorylase Enzyme and Cell Line as Targets Sami G. Alsabri
01:10 - 01:30
Plasma Adrenomedullin among Patients with Chronic Liver Diseases Enas Abdel Rasheed
01:30 - 01:50
Role of Uric acid in carcinoma of Breast Samah Elbusaifi
01:50 - 02:00
Discussion
02:00 – 03:00
Lunch Social Events
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October 13th
12:30 - 02:00 Pediatrics II Hall 2
Chairs: Prof.
Soah Abd El Dayem Sahar A. El Masry Soliman Albargati
12:30 - 12:45
Detection of Virulent Strains of Helicobacter Pylori and its Relation to Symptoms and Signs in Children Abd El Dayem S.
12:45- 01:00
Zero Prevalence of Intestinal Cryptosporidiosis among Children with Different Types of Malignancies in a Tertiary Hospital in Malaysia Lubna M. Elbishti
01:00 - 01:15
Developmental, Behavioral and Genetic Factors in Correlation with Attention Deficit Hyperactivity Disorder in Egyptian Children Khaled AL.Menabbawy
01:15 - 01:30
Genotype-Phenotype Correlations in Limb Reduction Defects: Review Article Adel Mohamed Ashour
01:30 - 01:45
Breastfeeding in some Maternal Problems Howayda Mahmoud Abd El Dayem
01:45 - 02:00
Discussion
02:00-03:00
Lunch Social Events
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October 13th
12:30 - 02:00 Public Health I Hall 3
Chairs: Prof.
Ahmed Yahia Mahmoud Al-Hussami Nasr Eldin Eltantawy
12:30 - 12:45
Patient Satisfaction from Quality of Primary Health Care in Benghazi, Libya Asharaf Abdul Salam
12:45 - 01:00
An Assesment of Geriatric Care Needs in Benghazi, Libya Mailud ElAmari
01:00 - 01:15
Health Status and Health Seeking Behavior of Adolescents and Youths in Benghazi Hajer Abd AlLatif Mohammed
01:15 - 01:30
Organizational and Occupational Risk Factors Associated with Work Related Injuries among Public Hospital Employees in Benghazi Omar Gnieber
01:30 - 01:45
Predictors of Nursing Faculty Members' Organizational Commitment in Governmental Universities Mahmoud Al-Hussami
01:45 - 02:00
Discussion
02:00 - 03:00
Lunch Social Events
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October 14th
09:00 - 10:30 Pharmacology Hall 1
Chairs: Prof.
Thomas Simmet Abdulla Alhawage Zamzam Elmahdi Burkan
09:00 - 09:15
Targeting NF-κ κB with the Natural Iκ κB Kinase Inhibitor Acetyl-11-keto-β-boswellic Acid in Macrophages Alleviates Skin Inflammation in a Transgenic Mouse Model of Psoriasis Thomas Simmet
09:15 - 09:30
Assessing the in vitro Antibacterial Activity of Methanolic Extract for some Plants Used in Libya as Traditional Medicine against Methicillin-Resistant Staphylococcus aureus Elfahem A.
09:30 - 09:45
Computational Design, Molecular Modeling and Synthesis of New 1,2,4-Triazole Analogs with Potential Antifungal Activities Laila A. Abou-zeid
09:45- 10:00
Drug Prescribing Trends in Three Polyclinics in Benghazi–Libya Salma A Bukhatwa
10:00 - 10:15
Possible Therapeutic Role of DehydroEpiandrosterone against GlucocorticoidInduced Secondary Osteoporosis in Female Rats Hanaa H. Ahmed
10:15 - 10:30
Discussion
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October 14th
09:00 - 10:30 Internal Medicine Hall 2
Chairs: Prof.
Adel A Nossier Taher Alshafah Soliman Aboserwail
09:00 - 09:15
Physical Therapy Exercise Approaches for Patients with Renal Transplantation Adel A. Nossier
09:15 - 09:30
Common MFV Mutations Analysis In Egyptian Patients With Familial Mediterranean Fever Tarik I. Zaher
09:30 - 09:45
Factors Associated with Pulmonary Tuberculosis in Misratah City- Libya Abubaker Elrotob
09:45 - 01:00
Risk Factors of Coronary Artery Disease in Benghazi Ekram A. Barakat
10:00 - 10:15
Antimicrobial Susceptibility and Virulence Genes Analysis of Helicobacter pylori Clinical Isolates Abdurrazag Nami
10:15 – 10:30
Discussion
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October 14th
09:00 - 10:30 Child Health Hall 3
Chairs: Prof.
Gamal Abdel Naser Yamamah Hala Goda Sanya Wahba
09:00 - 09:15
Evaluation of Health Status of South Sinai Children Using Simple Health Indicators Gamal Abdel Naser Yamamah
09:15 - 09:30
Thyroid Volumes in Egyptian South Sinai Schoolchildren: Compared to WHO/ International Council for the Control of Iodine Deficiency Disorders Normative Thyroid Volume Criteria Ashraf Fawzy Kamel
09:30 - 09:45
Television Watching Habits Associated with Obesity Risk Factors: A Survey of Benghazi Schoolchildren Saleh Elfadi
09:45 - 10:00
Work- Related Injuries among Child StreetLaborers in Benghazi: Prevalence and Predictors Jehan elbusaifi
10:00 - 10:15
Profile of Poisning in Children at Ibn Sinah Teaching Hospital, Sirt, Libya Soliman M. ELagha
10:15 – 10:30
Discussion
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October 14th
10:30 - 12:00 Surgery & Stem cell Hall 1
Chairs: Prof.
10:30 - 10:50
Hassan Abd El-Salam Mahsoub Mourd Amin Mostafa Alzaide Inferior Vena Cava Filter: Prophylaxis and Treatment of Pulmonary Embolism Mahsoub Mourd Amin
10:50 - 11:10
Stem Cell Therapy in Spinal Cord Injury with Paraplegia Ahmed Yahia Rizk
11:10 - 11:30
Estrogen Neuroprotection in Model Animals of Ischemic Brain Injury: A Look Into Gene Ragulation and Neural Stem Cell Proliferation Mohammad M. Khan
11:30 - 11:50
Fifteen Years Experience with Anterior Plating of the Lower Cervical Spine Fractures/Dislocation Hassan Abd El-Salam
11:50 - 12:00
Discussion
12:00 – 01:00
Coffee Break
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October 14th
10:30 - 12:00
Clinical Pathology and Molecular Genetics Hall 2 Chairs: Prof.
Abdul-Fatah Gbaj Adel Ashour Masanori Yoshioka
10:30 - 10:50
Detection of Mutation in the Breast Cancer Gene (BRCA1) Using Flourescence Technques Safa R. fitouri
10:50 - 11:10
Laboratory Diagnostics for the Study of Molecular Genetics and its Clinical Relevance Eman Hamza Thabet
11:10 - 11:30
Tumor Necrosis Factor Receptor II gene polymorphism in Rheumatoid Arthritis Dalia El Lebedy
11:30 - 11:50
Hypothermia Effect on Blood Coagulation: A New Rheometrical Approach for In-Vitro Haemostasis Monitoring A.M. Sowedan
11:50 - 12:00
Discussion
12:00 - 01:00
Coffee Break
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October 14th
10:30 - 12:00 Public Health II Hall 3
Chairs: Prof.
Khaled AL.Menabbawy Ahmed M. Byomi Fathia M. A. El Refaei
10:30 – 10:45
Epidemiological Studies on Some Zoonotic Enteric Protozoa in Different Areas of Nile Delta Ahmed M. Byomi
10:45 - 11:00
Assessing Malnutrition among Chemotherapy and/or Radiotherapy Benghazi Outpatients Using the Patient Generated–Subjective Global Assessment Diwa Pandey
11:00 - 11: 15
Study of Liquid Toxic Chemical Compound Poisoning in Benghazi Marim elglaly
11:15 - 11: 30
The Present Situation of Enteral & Parenteral Nutrition for Critically Ill Patients in Benghazi Public Hospitals Safaa AE Badr
11:30 - 11: 45
Eye Disease Current Events and News: Review article Fathia M. A. El Refaei
11:45 - 12:00
Discussion
12:00 – 01:00
Coffee Break
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October 14th
01:00 - 02:30 Hospital Acquired Infection Hall 1
Chairs: Prof.
Fatma Ziuo Emad Ezzat Ibrahim Abd El – Gwee
01:00 - 01:15
Epidemiology of Hospital Acquired Infection (HAI) at Benghazi Hospitals: 2006 -2007 Fatma Ziuo
01:15- 01:30
Economics of Hospital-Acquired (HAI) Control Program
Infections
Fatma Ziuo
01:30 - 01:45
Awareness of Hospital Infection Control Precautions among Health Care Workers at Benghazi 2007: A KAP Study Viny Rao
01:45 - 02:00
Hospital Hygiene And Precautions Hospital Acquired Infection Control
For
Ibrahim ABD El – Gwee
02:00 - 02:15
Quality of the Management System at Benghazi Performance and Environmental Assessment Fatma Ziuo
02:15 - 02:30
Discussion
02:30 – 03:30
Lunch
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October 14th
01:00 - 02:30
Environmental & Occupational Medicine Hall 2 Chairs: Prof.
Najib Mrizek Ahmed Shaban Gamal Abdel Naser Yamamah
01:00 - 021:15
Squamous Cell Carcinoma and Occupation: Results of a Case-Control Study in Sousse, Tunisia Maoua Maher
01:15- 01:30
Occupational Zoonotic Hazards within at Risk Employees in Contact with Wastages Racing Egyptian Sswines Concerning Brucellosis, Leptospirosis and Toxoplasmosis Ashraf M. Barakat
01:30 - 01:45
Occupational Risk Factors for Colorectal Cancer: Report of a Case-Control Study Rhif Houssem
01:45 - 02:00
Study of Cardiovascular Risk Factors Among Railway Traffic Controllers in the Railways Company of Tunisia Rhif Houssem
02:00 - 02:15
Occupational Asthma in the Tunisian Central Region: Etiologies and Professional Status Maoua Maher
02:15 - 02:30
Dissection
02:30 – 03:30
Lunch
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October 14th
01:00 - 02:30 Posters Hall 3
Chairs: Prof.
Ahmad Z. Al-Herrawy Sonia Allam Wafa Mossa Ramadan Adele Katiny Ashraf Fawzy Kamel The Glucosinolate Constituents Of Diplotaxis Acris and Their Biological Activity Radwan H. M.
Protective Action of Cuminum Cyminum against Cisplatin Induced Nephrotoxicity in Rats Zamzam Elmahdi Burkan
Pharmaceutical Role of Iron Formulations in Iron Deficiency Anemia
01:00 - 02:30
Wafa Ramadan
Kinetic Spectrophotometric Method For Hyoscine Butylbromide Determination In Pharmacetical Formulations Nagwa H. S. Ahmida
Synthesis, Characterization and Antibacterial activity of Some Schiff Base S.H.El-Garoshi
Modulation of Gene Expression in the Liver of Mice 48-H Post-Treatment with CCl4 Karam Mahdy
Toxicological Potential of Thiamethoxam Insecticide on Albino Rats and Determination its Residues in Some Organs Shehata E. M. Shalaby
Antioxidant Activity and Hypoglycemic Effect of the Egyptian Guava Leaves Volatiles Abdel Razik H. Farrag
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Fecal examination for occult blood: Evaluation of the present situation and forward looking for better standard Gashout .A
Study of Low Birth Weight (Lbw) and its Associated Factors in Derna City, Libya Nagah S.F. Mohamad
Role of Cytokines in Cancer Medicine Irshad AH
02:30 – 03:30
Lunch
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October 14th
03:30 - 04:00
Closing Ceremony & Recommendations Main Hall Chairs: Prof.
Ashraf Shaalan (Conference Chairman) Abdul-Fatah Gbaj (Conference Chairman) Karam Mahdy (Conference Co-Chairman) Azza Abdel shaheed (Conference Secretary General)
03:30 – 04:00
Lunch
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Conference Abstracts
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Plenary I
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Pandemic Influenza: Global and Regional Update Nasr Eldin Ahmed Eltantawy WHO – Egypt E-mail:
[email protected] Influenza pandemics are un-predictable but recurring events that can have severe consequences on societies worldwide. Historically, three major influenza pandemics with varying severity were recognized during the 20th century (1918, 1957, and 1968) where it was estimated to kill millions of people around the world. For any influenza pandemic, timing and impact remain unknown and could not be predicted. In April 2009, WHO received reports of sustained person to person transmission of a novel influenza A sub-type (H1N1 2009) from Mexico and USA, which spreaded very fast across the globe. As of 13th of June 2010, more than 214 countries and overseas territories or communities have reported 18,172 deaths, where AMRO region reported the highest number of deaths, followed by EURO, SEARO and EMRO regions. Overall, case fatality rate was just over 1% worldwide. As of 2nd of January 2010, EMRO region reported 58,478 laboratory confirmed cases of pandemic influenza A (H1N1) 2009 to WHO by all Member States. Out of this number, 708 deaths occurred. Iran reported the highest number of deaths (140) followed by Syria and Saudi Arabia which reported 110 and 97 consequently. This pandemic is classified as mild in nature compared to past pandemics, and the virus remains of low virulence. In EMRO region the high-risk groups were similar as anywhere else, however, almost one third of patients admitted to Intensive Care Units were previously healthy persons. Data compiled by EMRO show that almost 80% of cases have occurred among the age group 5-49 years with no gender difference. Only 1% of cases occurred in patients aged over 65 years. 285 cases showed H275Y mutations and other variants, however almost all resistant cases were sensitive to zanamivir. EMRO has conducted a series of consultative and inter-country workshops to support Member States in managing and responding to the pandemic. The region was faced by multiple challenges particularly with surveillance, capacity of health care systems and access to vaccines. This pandemic raised the importance of research to fill the gaps in our understanding of influenza disease and identify priority areas for immediate attention. WHO has identified 5 important streams of research, namely: reducing the risk of emergence of pandemic influenza; limiting the spread of pandemic, zoonotic and seasonal epidemic influenza; minimizing the impact of influenza; optimizing the treatment of patients; prompting the development and application of modern public health tools.
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Influenza Viruses: The 21th Century Threat Mohamed Ahmed Ahmed Ali Department of Water Pollution Res.Virology Lab. Division of Environmental Sciences, National Research Centre E-mail:
[email protected] Vaccination is considered the most-effective preventive measure to control influenza infection. Currently, inactivated vaccines are the main stream of influenza prophylaxis. They are usually prepared from a virus that is grown in chicken embryonated eggs and inactivated using formaldehyde or β-propiolactone for whole-virus vaccine formulation. However, the high pathogenicity of the circulating H5N1 viruses presents difficulties for vaccine preparation. HPAI H5N1 virus cannot be used as a seed virus for inactivated vaccine production because not only its virulence threatens the lives of vaccine producers, but also it complicates efforts to obtain high-quality allantoic fluid with acceptable virus titers from embryonated eggs. Seed viruses for inactivated vaccines must be antigenically similar to the circulating viruses and grow efficiently in eggs. New vaccines that exploit reverse genetics technology are being developed, and the knowledge that the pathogenicity of avian influenza viruses is primarily determined by HA cleavability. The original reverse genetics system, which was developed by Palese and colleagues, enabled the generation of influenza viruses possessing a single-gene segment from cloned cDNA. However, this method was technically demanding and was subsequently replaced by plasmid-based reverse genetics systems developed by Hoffmann and others which enable the production of infectious influenza virus entirely from cloned copies of its genome. In Egypt, we succeeded to produce a low pathogenic H5N1 from our currently circulated high pathogenic avian influenza viruses using the reverse genetic technology. The presence of this technology will help us to produce vaccine strains of H5N1and H1N1 to be used for vaccine design and production.
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Pediatrics I
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Bone Metabolism Alteration in Children with Type 1 Diabetes Mellitus *Enas R Abdel Hameed 1; Maysa T Saleh 1; Lobna S Sherif 1; Noura A Badawy 2 ; Maha Rasheed 2; Gamila S El-Saeed 3 Departments of Child Health 1, Chemical & Clinical Pathology 2 and Medical Biochemistry 3, National Research Centre, Cairo, Egypt *Presenting author e-mail:
[email protected] Objectives: To study the potential effects of diabetes on bone metabolism. Methods: This case control study was conducted on 40 children with type 1 diabetes mellitus (DM1), between 4 and 12 years old, who had been followed at the endocrinology, clinic, pediatric hospital, Cairo University. Twenty healthy children (5 girls), with similar economic and culture status, were recruited as controls. Serum level of osteocalcin was measured as bone formation marker by host ELISA- kit and urinary levels of deoxpyridinoline (DPD) were measured as bone resorption marker by highperformance liquid chromatography (HPLC). Results: Serum concentration of osteocalcin was significantly decreased in children with DM1 versus control. Meanwhile, a significant increase in the urinary DPD level in diabetic children compared to control was observed. A highly significant positive correlation between serum osteocalcin and duration, as well as severity was observed (p< 0.001). On the other hand, urinary DPD showed an insignificant negative correlation with severity and duration of the disease. No correlation was found between serum osteocalcin and urinary DPD (p>0.05). Conclusion: Altered mineral metabolism exists as one of the chronic complications of diabetes mellitus in children. Further efforts should be necessary to clarify the detailed mechanism and to establish appropriate preventive measures. Keywords: Diabetes mellitus type1, osteoporosis, bone markers, osteocalcin, deoxypyridinoline.
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Pulmonary Function Changes after a Rehabilitation Program to Asthmatic Children Zeinab Mohamed Radwan1; Hala Goda Elnady2; Dalia Ismail Attia3; Eman Yassin Salem3; Maysa Samir Mohamed2 Pediatric Department1 Cairo University, Department of Child Health 2, National Research Center, Cairo, Fitness and Rehabilitation Unit 3, Institute of Industrial Medicine and Occupational Diseases, Cairo University, Egypt. *Presenting e-mail:
[email protected] Background/Aim: Asthma is a chronic inflammatory disease with an underlying inflammatory component. Its prevalence has recently increased dramatically. A new guideline in the treatment of asthma is the pulmonary rehabilitation program in the form of exercise training, in addition to drug therapy. The aim of the work of this study was to show the clinical and functional improvement in asthmatic children after a schedualized training program, and to evaluate the efficacy of physical activity on both symptoms and pulmonary functions, aiming to modify the asthmatic children's life style. Subjects & Methods: Forty asthmatic children after with moderate persistent asthma, aged from 6 to 12 years, were categorized into two groups. Group A: comprised 20 asthmatic children with mean age of (7.95) years, who received drug therapy in the form of inhaled corticosteroids and oral Montelukast, and had undergone a rehabilitation program. Group B: comprised 20 asthmatic children, who received drug therapy alone with mean age of (8.32) years. The ventilatory function tests were done to both groups before and after treatment. Results: There was a highly significant improvement in the ventilatory function variables (FVC%, FEV1%, FEV1/FVC%, FEF25%, FEF50% and FEF25-75% and MVV %) in group A as compared with group B (P= 3 & ≤ 22 CFU, as determined by analysis of proteinase K-phenol- chloroform treated pure strains of E. coli. Also a PCR assay with tow nested pairs of primers selected from conserved sequences within a 2.3 kb randomly cloned DNA fragment from the S. typhimurium chromosome and gel electrophoresis detection of PCR target was used for detection of Salmonella, without prior enrichment step for the purpose of determining water quality. The sensitivity of the nested PCR assay was > 6 & ≤ 17 CFU, as determined by analysis of proteinase K-phenol- chloroform treated pure strains of S. Typiymurium. Results: Testing of 120 drinking water samples collected from different water treatment plants at Great Cairo, revealed that the multiplex PCR method was less sensitive for detection of total coliform and E. coli than MF. On the other hand, no obvious differences were observed between nested PCR and MF methods used for detection of Salmonella, as all 120 drinking water samples tested showed negative results with both of them. Conclusion: In conclusion, the study showed that instead of PCR disadvantages these tools are rapid and possesses the ability to detect several bacterial indicators or pathogens in one reaction and in the same time within 24 hours, with high specificity and therefore could replace or augment cumbersome, inaccurate and often misleading fecal indicator tests, hence no need for confirmation. This investigation suggests the persistence of inhibition phenomena and proves the necessity of developing internal controls in order to interpret the negative results. This investigation recommends that PCR technique must consequently be associated with a viability test. Yet this viability concept is fundamental for interpreting the result in terms of public health.
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The Effect of Sodium Dichloroisocyanurate on Toxocara Canis Eggs Muftah Younis and Sonia Allam* Parasitology Department, Faculty of Medicine, Garyounis University, Benghazi, Libya *Presenting author e-mail:
[email protected] Background/Aim: Visceral larva migrans infection is considered a public health problem in many countries. A simple and cheap method to control infection is by decontamination of raw vegetables from the infective eggs. Chemical disinfectants can be used. These act in different modes; some are oxidizants as Potassium permanganate (KMnO4). It kills eggs by destroying the cell wall via oxidation. Sodium dichloroisocyanurate (NaDCC) is a chlorinated cleaner. Hydrochlorous acid is the active agent, which have a microbicidal activity. The present study aimed to investigate the effects of KMnO4 and NaDCC on eggs of Toxocara canis. In addition, their safety when used in washing green vegetables was studied. Material and methods: Eggs of Toxocara canis were obtained from the uterus of the adult worms. Disinfectants used were: KMnO4 purple solution in a concentration of 24 mg/liter water, or NaDCC colorless solution. One tablet / L water (Coreline Chemicals U.K). Green vegetables: Leaves of lettuce, parsley and Celery were used. Results and Conclusion: NaDCC had more powerful destructive effect on infective eggs. It was more acceptable than KMnO4 as its solution was colorless and tasteless, so it was easily rinsed in water in comparison to the purple astringent solution of KMnO4. Moreover, KMnO4 being an oxidizant, may alter the vegetable cells, which may lead to loss of their vitamins.
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Plenary II
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Initial Trauma Management Mahsoub M. Amin Vascular Surgery, Faculty of Medicine, Al Azhar University, Cairo, Egypt E-mail:
[email protected] Trauma happens worldwide and it strikes without warning. Its debilitating and devastating characteristics takes its toll on victims, families, friends, and even the family of healthcare professionals committed to serve their communities. As a professional health care provider, you are faced with an array of situations and decisions that directly influences the quality and success of overall trauma care. Over the past 50 years, assessment of trauma patients has evolved because of an improved understanding of the distribution of mortality and the mechanisms that contribute to morbidity and mortality in trauma. Mortality can be grouped into immediate, early, and late deaths. Immediate deaths are caused by a fatal disruption of the great vessels, heart, and lungs or a major disruption of body cavities. Immediate mortality occurs at the scene of injury. Early deaths may occur any time from minutes to hours after the injury. These patients frequently arrive at a hospital before death, which usually occurs because of a cardiovascular and/or pulmonary collapse. Late trauma mortality peaks from days to weeks after the injury and is primarily due to sepsis and multiple organ failure. Organized systems for trauma care are focused on the salvage of a patient from early trauma mortality, whereas critical care is designed to avert late trauma mortality. Objectives are: to provide basic knowledge necessary to identify and treat those traumatized patients who require rapid assessment, resuscitation and stabilization of their injuries; and to highlight the need for early recognition and timely intervention in specific life-threatening conditions.
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Towards A Strategy in the Arab World for Better Maternal-Fetal Health Care Khaled R Gaber Prenatal Diagnosis and Fetal Medicine Department National Research Centre, Cairo – Egypt E-mail:
[email protected] Background: The future strategy of maternal-fetal health care and research in the Arab World should mainly focus on solving pregnancy-related problems. This can be done through different approaches; increasing the training and education level of the next generation of young researchers, to focus research on understanding and early prevention of diseases that may affect the mother and the fetus. Pregnancy related disorders (preeclampsia, overweight, preterm labor), and genetic disorders (Hb disorders, neurogenetic disorders, birth defects) are responsible for a significantly high proportion of perinatal morbidity and mortality, in addition to infant deaths and handicapping mainly mental retardation. In conclusion, this strategy should have a base consisting of: public awareness and education of genetic disorders and pregnancy related problems, pre-pregnancy and early prenatal screening and diagnosis protocols, in addition to establishment of general and specific genetic services.
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Reproductive and Fetal Medicine
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Maternal Vitamin B12 and the Risk of Fetal Neural Tube Defects in Egyptian Patients Khaled R. Gaber*1, Mona K. Farag1, Somaya E.T Soliman2, Hala. EL-Bassyouni 3, Ghada El-Kamah3 1
Prenatal Diagnosis and Fetal Medicine Department, 3Clinical Genetics Department, National Research Centre, 2 Radioisotope Department, Nuclear Research Centre, Cairo, Egypt * Presenting author e-mail:
[email protected] Objective: Folic acid insufficiency is a known risk factor for neural tube defects (NTDs), while the role of vitamin B12 is questionable. Thus, our purpose was to investigate whether low maternal serum vitamin B12 is associated with an increased risk of NTDs. Materials and Methods: The study groups included 36 women who were, or had been, pregnant with a NTD-affected fetus. The control groups comprised 35 healthy women with normal prior or current pregnancy and uncomplicated obstetric histories. Fasting plasma homocysteine, serum folate and cobalamin (vitamin B12) were performed. Odds ratio (OR) and 95% confidence intervals were calculated. Results: The fasting homocysteine was significantly higher in the study groups as compared to the controls. The median serum folate concentrations were similar in cases and controls, while the median vitamin B12 concentrations were significantly lower in the study groups compared to the controls. Low vitamin B12 concentration was associated with an approximately 2- to 3-fold increased risk for NTDs. Conclusion: Low maternal serum values of vitamin B12 can be considered an important etiologic factor for the development of neural tube defects in our population. This may help in both genetic counseling for families with a history of NTD malformation, and as a pre-conceptional prophylactic measure by maternal supplementation of vitamin B12 and folic acid.
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A Novel Endometriosis Inducing Factor in Women with Endometriosis Khaled Rasheed, 2 Hazem Atta, 3 Tamer Taha,* 3 Osama Azmy2, Dina Sabry, Mourad Selim, 1Ahmed El-Sawaf, 3Mamdouh Bibars, 2 Mohammed Talaat Abd ElAziz, 1Abd El-Meguid Ramzy 4Wael El-Garf 1
3
Departments of 1 Obstetrics and Gynecology; 2 Unit of Biochemistry and Molecular Biology, Medical Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University; and Departments of 3Reproductive Health and 4 Department of Biomedical Technology, National Research Centre *Presenting author e-mail:
[email protected] Aim: To confirm the hypothesis of the presence of a possible endometriosis inducing factor(s) (EIF) in the blood of women with endometriosis. Patients and Methods: Forty infertile women were studied. They were classified into a study group comprised of 20 women that have different degrees of endometriosis and a control group consisted of twenty women without endometriosis. The women sera were co-cultured with Mesenchymal stem cells (MSCs) which were followed up weekly to look for changes in their morphology and to detect Annexin 1 marker and β-actin gene by reverse transcriptase polymerase chain reaction. Results: MSCs cultured with sera of cases with minimal, mild, moderate and severe endometriosis, showed morphological changes to be columnar and cuboidal shaped cells -resembling endometrial cells and glands- by the 4th week in 40%, 60%, 60% & 100% of cases respectively. These cells were detected as early as the first week in women with moderate and severe types (20% for each group). The percentage of the change into endometrial like cells did increase among the four groups where it was 25±19.1%, 30±25.8%, 45±29.9% and 75±37.9% respectively. Moreover, increasing number of cases are detected weekly, the more severe the disease is. None of the cultures of serum of the control group had made such changes all around the entire duration of the study. Furthermore, with more differentiation there was a considerable decrease in number of stem cells. These differentiated cells expressed markers of endometriotic changes; expression of proliferative marker (Annexin-1) and house keeping gene (β-actin). Conclusion: It was suggested that sera of women with endometriosis posses a factor(s) that enables the MSCs to be transformed into endometrial like cells and glands in vitro. This finding supports a new theory for the etiology of endometriosis. This observation may have a tremendous effect on the therapeutic implications of this debilitating condition. Further research with large randomized control studies are urgently needed to confirm this finding and clarify the nature of this substance and its molecular composition.
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Prevalence of Cesarean Section and It’s Related Factors In Subrata Hospital Libya Mawia Mohamed M. Besht Medical Faculty, Universiti Kebangsaan Malaysia E-mail:
[email protected] Background/Aim: Caesarean section (c-section) is the surgical delivery of a baby through an incision (a cut) in the mother’s abdomen and the uterus to deliver one or more babies It is usually performed when a vaginal delivery would put the baby's or mother's life or health at risk, although in recent times it has been also performed upon request for childbirth that could otherwise have been natural. The world health organization (WHO) recommends that the rate of Caesarean sections should not exceed 15% in any country. The purpose of this study is to determine the related factors and association such as age of mother, height of mother, breech presentation and fetal distress with caesarean section deliveries. Methods: Cross sectional study. The population in this study is all mothers who deliver by cesarean section and vaginal deliveries admitted to gynecological and obstetric word in Subrata hospital during the period of January 2010 to June 2010. Results: Variables data will be traced from the medical records and will be recorded in a preplanned data sheet. Conclusion: Cesarean section rates have been increasing worldwide, and are a growing concern in many countries. High rates of cesarean deliveries are now an international phenomenon, reflecting, in part, increased hospital-based delivery and access to healthcare
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Assessment of Common Types of Vaginal Infections among Women Attending Gynecology Clinics at El-manial University Hospital: A proposed Plan of Action *Amel Dawod Kamel, Shadia Abd El kader, Soumaya Mohamed Hassan, and Nada Nabil Nawar Maternal and Newborn Health Nursing Department, Faculty of Nursing, Obstetrics and Gynecology, and Clinical Pathology Department, Faculty of Medicine, Cairo University *Presenting author e-mail:
[email protected] Background/Aim: Infectious vaginitis is most common among women of reproductiveage and is usually from bacterial vaginosis, trichomoniasis or vulvovaginal candidiasis. Some vaginal infections are transmitted through sexual contact, but others such as candidiasis (yeast infections) are not. This study aims to assess the prevalence of the most common types of vaginal infection among women attending gynecology clinics at El-manial University Hospital as well as to explore the effect of nursing health education on relieving vaginitis. Methods: Exploratory design was adopted to achieve the required aims. A total of 400 women had abnormal vaginal discharge were recruited. Three tools were designed to collect the data: Interviewing questionnaire sheet, -laboratory investigations and health education progress record. Data were collected through four steps. Step one was an interview to collect the socio-demographic data. Step two for physical, vaginal examinations and take the laboratory investigation, step three for applying the health education for 10% of the total sample and follow. Step four was analyzing the data. Results: The study results showed that the mean age of the sample was 31.44 ± 6.14 years old. The prevalence of vaginal infection among total sample was 244 women (58.8 %). Vaginal Candidacies affecting 156 women (40.9%), Bacterial Vaginosis were identified in 39 women (10.2%), twenty three women (6%) had Trichomonas vaginalis, and six women (1.6%) had mixed infection. Also, the results indicated that nursing health education eliminate the women complains by more than 50 % and reduce the prevalence of vaginal infection by 65 %with highly statistical significance. Conclusion: The symptoms of vaginal infections and their incidence can be reduced by proper laboratory investigation, correct diagnosis and well constructed nursing health education. Keyword: Prevalence Vaginal Infections – Nursing Health education-lab investigation
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The Effect of Pelvic Floor Muscle Training on Improving its Strength among Women with Stress Urinary Incontinence Hayat I. Gommaa Chairman of Maternal and Newborn Health Nursing Department, Faculty of Nursing, Cairo University E-mail:
[email protected] Background/Aim: Pelvic floor muscle training (PFMT) is the most commonly used physical therapy treatment for women with stress urinary incontinence. This study aims to examine the effect of pelvic floor muscles training on improving its strength among woman with stress urinary incontinence. It is hypothesized that women who perform pelvic floor muscles training for at least twelve weeks will show improvement in the strength of pelvic floor muscles by Perinometer reading. Methods: A Convince sample of 60 women with stress urinary incontinence was recruited from urodynamic unit at the obstetrics and gynecology hospital were undergoing three education sessions. Three tools were used, structure interview questionnaire, Perinometer and follow up sheet. Data were collected through four phases, assessment, intervention, follow up and evaluation. Results: The study results showed that: the mean age was 38.91 ± 8.14. Sixty six percent of women were 2-5 gravida. Eighty three point three percent were had daily leaking which interfere with daily activities VS zero% after PFMT. Nocturia took place among 50%VS zero% after PFMT. The initial mean value of Perinometer reading was 26.96 ±6.27 while after 6 weeks of training it was 32.18±7.33 and 52.0167±12.7545 after 12 weeks. Conclusion: Continued pelvic floor muscles training improves its strength as well as prevents the urine leakage. Applying training for at least 12 weeks is recommended. Keywords: Pelvic floor muscle training – Perinometer- Stress urinary incontinence
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Pediatric Nutrition
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Prevalence of Metabolic Syndrome among Obese Egyptian Children and Adolescents Nayera E. Hassan*1, Lobna Shreif2, Sahar A. El-Masry1,Walaa Fouade2, Amany Elwakade3, Mona Anwar4, Safaa T. Zaki 2and Azza AbdElshahid2 1
Biological Anthropology Dept., 2Child Health Dept,3Medical Biochemistry, Children with special needs, Medical Research Division,National Research Centre, Dokki, Giza, Egyp *Presenting author e-mail:
[email protected]
4
Objective: The aim of this study was to assess the prevalence of metabolic syndrome and the other metabolic features in obese Egyptian children and adolescents. Methods: The study included 462 obese children and adolescents (body mass index > 95th percentile), 122 prepubertal and 340 pubertal, aged between 7 and 18 years. Each subject was submitted to clinical, anthropometric and laboratory assessment. The diagnosis of hypertension, impaired fasting glucose, hyperinsulinieamia, insulin resistance, dyslipideamia and metabolic syndrome were defined according to modified WHO criteria adapted for children (1998) and Grundy (2004). Results: Metabolic syndrome was found in 39.7%, with a significantly higher rate among prepubertal children aged 7–11 years (45.5%) than among pubertal adolescents aged 12–18 years (37%) ( p < 0.001). The prevalence of metabolic syndrome was higher in girls than boys in the pubertal age groups and total sample, while boys have the higher prevalence in the prepubertal age. Hypertension was significantly more common in adolescents (22.3%) than children (14.8%) with obesity, as expected (p
