Postoperative histopathological examination revealed multiple ulcers containing ... regular basis. He was positive for HLA B5 and pathergy test was negative.
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The Saudi Journal of Gastroenterology Volume 14, No. 2, Rabi’ al-Awwal 1429 H; April 2008
CONTENTS Editorial Hepatitis C Treatment: Trial by Design Khalid I. Bzeizi
51
Original Articles Correlation of Gastroesophageal Reflux Disease Symptoms with Body Mass Index Shamail Zafar, Israr U. Haque, Ghias U. N. Tayyab, Ameed U. Rehman, Adeel U. Rehman, Nusrat U. Chaudhry
53
Sustained Virologic Response to Peginterferon α-2a and Ribavirin in 335 Patients with Chronic Hepatitis C: A Tertiary Care Center Experience Hamad Al Ashgar, Mohammed Q. Khan, Ahmed Helmy, Khalid Al Swat, Abdullah Al Shehri, Abdalla Al Kalbani, Musthafa Peedikayel, Khalid Al Kahtani, Mohammed Al Quaiz, Mohammed Rezeig, Ingvar Kagevi, Mohammed Al Fadda
58
Laparoscopic Cholecystectomy in Cirrhotic Patients: Feasibility in a Developing Country Mohammad Tayeb, Muhammad R. Khan, Nazia Riaz
66
Hepatitis B Virus Sero-Prevalence Among Pregnant Females in Saudi Arabia Mohammed A. Alrowaily, Mostafa A. Abolfotouh, Mazen S. Ferwanah
70
Male Gender is not a Risk Factor for the Outcome of Laparoscopic Cholecystectomy: A Single Surgeon Experience Abdulmohsen A. Al-Mulhim
73
Case Reports Intra-Abdominal Manifestations of von Recklinghausen’s Neurofibromatosis Rajul Rastogi
80
Ectopic Sebaceous Glands in the Esophagus: A Case Report and Review of Literature Ramachandra V. Bhat, Rupnarayan R. Ramaswamy, Lakshmana Kumar C. Yelagondahally
83
Multiple Perforations along the Entire Colon as a Complication of Intestinal Behcet’s Disease: A Rare Case Umit Sekmen, Tolga Muftuoglu, Julide Sagiroglu, Ozgun Gungor
85
Hemangiopericytoma of Greater Omentum Presenting as a Huge Abdominal Lump Damodar Chatterjee, Pradip Sarkar, Niladri Sengupta, W. Gopimohan Singh
88
New Horizon Y-90 Microshperes in the Treatment of Unresectable Hepatocellular Carcinoma Abdullah Al-Kalbani, Yasser Kamel
90
Debate Helicobacter pylori Eradication in Nonulcer Dyspepsia: Does It Really Matter? Ahmad S. AlMalki
106 Volume 14, Number 2 Rabi’ al-Awwal 1429 H April 2008 106 CMYK
93 The Saudi Journal of Gastroenterology
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Helicobacter pylori Eradication Therapy in Nonulcer Dyspepsia is Beneficial Mohammed Q. Khan
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Letters to the Editor Tuberculosis of Gall Bladder Presenting as Empyema Leo F. Tauro, John JS Martis, Hejmadi D. Shenoy
101
Presumed Acute Pancreatitis During Chickenpox Infection in an Otherwise Healthy Male Roberto Manfredi
102
Unusual Presentation of Esophageal Tuberculosis Mimicking Malignancy Rashmi Patnayak, Mandyam K. Reddy, Sriram Parthasarathy, Mutheeswaraiah Yootla, Venkatarami Reddy, Amitabh Jena
The Saudi Journal of Gastroenterology
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107 Volume 14, Number 2 Rabi’ al-Awwal 1429 H April 2008 CMYK 107
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Case Report
Multiple Perforations along the Entire Colon as a Complication of Intestinal Behcet’s Disease: A Rare Case Umit Sekmen, Tolga Muftuoglu, Julide Sagiroglu, Ozgun Gungor
Department of General Surgery, Haydarpasa Numune Education and Training Hospital, Istanbul, Turkey Address: Dr. Umit Sekmen, Haydarpasa Numune Egt. Ve Aras. Hast., Genel Cerrahi Klinigi, Istanbul, Turkey. E-mail: usekmen@yahoo. com
ABSTRACT Colonic complications of Behcet’s disease due to intestinal involvement are rarely reported in the literature. Ulcers are the most frequently seen intestinal complications that cause bleeding and perforation predominantly in the ileocecal region. In this article, we report a patient with Behcet’s disease who presented with multiple perforations along the entire colon. Postoperative histopathological examination revealed multiple ulcers containing lymphocytic inÞltrations in the small peripheral and submucosal venules. Intimal thickening and fresh intraluminal Þbrin thrombosis were also seen in these venules. Key Words: Colonic perforation, intestinal Behcet’s disease, ulcer Received 29.06.2007, Accepted 09.01.2008 The Saudi Journal of Gastroenterology 2008 14(2): 85-7
Behcet’s disease (BD) is a rare, chronic, and lifelong disorder presenting with inflammation of blood vessels throughout the body. This disorder may also cause various types of skin lesions, arthritis, bowel inflammation, and meningitis. Additionally, intestinal, hepatic, splenic, and pancreatic involvement rarely occur during the course of the disease.[1,2] Intestinal ulcerative changes are seen in
