Correlations of Serum Hormones and Bone Mineral Density with

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Oct 13, 2018 - This study of the effect of GLP-1 on high-fat-induced bone loss and its ... fracture and balance ability of postmenopausal patients and effects of ...
CLINICAL RESEARCH e-ISSN 1643-3750 © Med Sci Monit, 2018; 24: 7309-7315 DOI: 10.12659/MSM.910792

Correlations of Serum Hormones and Bone Mineral Density with Fracture and Balance Ability of Postmenopausal Patients and Effects of Calcitriol

Received: 2018.04.25 Accepted: 2018.05.16 Published: 2018.10.13

Authors’ Contribution: Study Design  A Data Collection  B Analysis  C Statistical Data Interpretation  D Manuscript Preparation  E Literature Search  F Collection  G Funds



AE 1 AE 2 B 1 C 3 D 4 F 5 EG 1

Lili Xu* Bing Liu* Peng Li Juanjuan Li Jun Wang Jialin Han Nailong Yang

1 Department of Endocrinology and Metabolism, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, P.R. China 2 Department of Vascular Surgery, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, P.R. China 3 Department of Endocrinology, Qilu Hospital of Shandong University, Qingdao, Shandong, P.R. China 4 Department of Endocrinology, The 401 Hospital of PLA, Qingdao, Shandong, P.R. China 5 Department of Endocrinology, Weifang Hospital of Traditional Chinese Medicine, Weifang, Shandong, P.R. China

Corresponding Author: Source of support:

* Lili Xu and Bing Liu are co-first authors Nailong Yang, e-mail: [email protected] This study of the effect of GLP-1 on high-fat-induced bone loss and its mechanism of action was supported by the Affiliated Hospital of Qingdao University Hospital 2014 Youth Fund Project (grant no. 2202)



Background:



Material/Methods:



Results:



Conclusions:

The aim of this study was to analyze the correlations of serum hormones and bone mineral density (BMD) with fracture and balance ability of postmenopausal patients and effects of calcitriol on them. The clinical data of 164 postmenopausal female patients with osteoporosis (OP) treated in our hospital were retrospectively analyzed. The incidence rates of OVCF, balance index score (BIS), front-back ratio (FBR), and right-left ratio (RLR) in the normal BMD group, reduced BMD group, and OP group showed increasing trends, and there were statistically significant differences in comparisons among groups (p