Course Specification pharmaceutical organic chemistry 1

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1. Course Specification pharmaceutical organic chemistry 1. Programme(s) on which the course is given: B. Sc. in pharmaceutical science. Major or Minor ...
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Assiut University Faculty of Pharmacy

Department of Pharmaceutical organic chemistry

Course Specification pharmaceutical organic chemistry 1 Programme(s) on which the course is given: B. Sc. in pharmaceutical science Major or Minor element of programmes: Major Department offering the programme: Faculty of Pharmacy Department offering the course: Pharm. Org. Chem. Academic year / Level: 2011/2012, First year-1st semester Date of specification last approval: 15/11/2011 1-Basic Information Title: pharmaceutical organic chemistry 1 Code: PHC-215 Level: First year-1st semester

Department: Pharm. Org. Chem.

Unit: N.A Lecture: 3 hours /week

Tutorial/Practical: 3 hours /week

Total: 6 hours /week 2- Aims of Course The aims of this course include: Providing students with knowledge needed in the area of pharm. organic Chem. and to prepare them for related subjects in the design and synthesis of simple organic molecules. Also providing students with skills related to chemistry so they can complete in the higher years. Students are also taught the necessary knowledge needed to practice the pharmacy profession in academic institutions and research centers.

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3- Intended Learning Outcomes of Course(ILOs) By the end of this course, the student should be able to: a- Knowledge and Understanding: al- Define basic principles in pharm. org. chem. especially aliphatic organic compounds such as alcohols, carbonyl and dicarbonyl compounds. a6- Define chemical reaction mechanisms and their application in the synthesis of simple medicinal agents. In addition to illustrate different potential interactions between organic molecules. b- Intellectual Skills: b3- Apply the gained basic informations to formulate and suggest the methods of synthesis and conclude properties of medicinal agents. c- Professional and practical Skills: c7-Perform safety Handling measures for chemicals in the lab. and be aware of the rules of good laboratory practice (GLP) and to diagnose elements in organic compounds and determine their functional groups. d- General and Transferable Skills: d1-Written essays skills through applying information technology skills, including word processing, database use, archiving data and information retrieval on important name reactions through online computer searches ability to perform and internet communications. d9- Team working skills and ability to perform oral presentations and seminars to small group of students. d12- Manage time effectively. d13- Social and cultural activities through, problem solving and decision making abilities in a variety of theoretical and practical situations.

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4- Course Contents: Topic

No. of hours

Introduction to alkyl halides/ laboratory safety Alkyl halides: prep. & reactions/ qualitative and quantitative elemental analysis Unsaturated halogen derivatives/ Problems Alcohols, ethers: prep. & reactions/ Lassaigne’s test, test for nitrogen Amine: prep. & reactions/ test for sulfur Introduction to carbonyl compounds/ test for sulfur Aldehydes, ketones: prep. & reactions/ test for halogen in absence of nitrogen and sulfur Carboxylic acid/ test for halogen in absence of nitrogen and sulfur Carboxylic acid derivatives/ test for halogen in presence of nitrogen and sulfur Dicarbonyl and dicarboxylic acid derivatives/ Revision -Organometallic compounds/ practical exam Total hours

5- Teaching and Learning Methods 5.1-Lectures 5.2- Practical training (Laboratory) 5.3- Tutorials and class activity 5.4- Discussion and net research 6- Teaching and learning methods for disables Not applicable 7- student Assessment a- Student Assessment methods

7.1-Written exam to assess ILOs: a,b,c 7.2- oral to assess ILOs: a,b and d 7.3- Practical exam to assess ILOs: a,b,c and d 3

Lecture (3 hr)

3

1

Tutorial / Practical (3 hr) -

9

1

2

3

1

-

12

2

2

9

1

2

3

1

-

12

2

2

9

1

2

9

1

2

9

1

1

9

2

1

87

14

14

7.4- Quiz to assess student follow up of lessons; ILOs: a and b. b- Student Assessment Schedule

No. 1. 2. 3. 4.

Assessment Quiz Practical Exam Oral Exam Final written Exam

week 10th week 14th week At the end of semester At the end of semester

c- Weighting of Assessments

No. 1. 2. 3. 4.

Exam. Quiz Final-Term Examination Oral Examination Practical Examination Total

Mark 15 70 20 45

% 10 46.66 13.33 30 100%

8- List of References a-Course Notes

An introduction to Pharm. Organic Chemistry Vol. I b- Essential Books (Text Books) ٠T.W.Graham Solomons, Organic chemistry, 9th ed., John Wiley and Sons, INC, New York, 2008. ٠Furniss, Hanna Ford, Smith, Tutchell, Vogel's textbook of Practical Organic Chemistry, 5th ed, Longman Group UK Ltd, England, 1989. c-Recommended Books ٠Jerry March, Advanced Organic Chemistry, Reactions, Mechanisms, and structures, 4 th ed. John Wiley and Sons, New York, 1992. d- Periodicals, Web Sites, …. etc Journal of organic chemistry, biomed.net 9- Facilities Required for Teaching and Learning: Computer modeling and computational chemistry programs. Course Coordinator: Dr. Samia Galal Ahmed Abdel-Moty Head of Department: Dr. Mostafa A. Hussein

Date: 15/11/2011

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University of Assiut

Course Title : Pharm. Org. Chem.

Faculty of Pharmacy

Course Code. PHC-222

Department: Pharm. Org. Chem.

Matrix of the Intended Learning Outcomes (ILOs) of the Course Topic

Week

Knowledge and Understanding

Introduction to alkyl halides

1st

Alkyl halides: prep. & reactions

2nd

Unsaturated halogen derivatives

3th

a1,a6

4th - 5th

a1,a6

Alcohols, ethers: prep. & reactions Amine: prep. & reactions

General and Transferable Skills

b3

c7

d1,d9,d12,d13

c7

d1,d9,d12,d13

C7

d1,d9,d12,d13

a1,a6

6th

b3

7th 8th 9-10th

a1,a6 a1,a6 a1,a6

Carboxylic acid

11h

a1,a6

Carboxylic acid derivatives. Dicarbonyl and dicarboxylic acid derivatives. Organometallic compounds

12th 13th

a1,a6 a1,a6

14-15 th

a1,a6

Introduction to carbonyl compounds Quiz Aldehydes, ketones: prep. & reactions

Intellectu al Skills

Professional and practical Skills

Course Coordinator: Dr. Samia Galal Ahmed Abdel-Moty Head of Department: Dr. Mostafa A. Hussein

Date: 15/11/2011 5

d1,d9,d12,d13 b3 b3

d1,d9,d12,d13 c7

b3

c7

d1,d9,d12,d13

d1,d9,d12,d13