Jun 7, 2013 - Johnny Ho-Yin Wong & Ralph Jasper Mobbs. Received: 12 February 2012 /Revised: 11 December 2012 /Accepted: 10 March 2013 /Published ...
Neurosurg Rev (2014) 37:23–37 DOI 10.1007/s10143-013-0483-9
REVIEW
Current status of bone graft options for anterior interbody fusion of the cervical and lumbar spine Anthony Minh Tien Chau & Lileane Liang Xu & Johnny Ho-Yin Wong & Ralph Jasper Mobbs
Received: 12 February 2012 / Revised: 11 December 2012 / Accepted: 10 March 2013 / Published online: 7 June 2013 # Springer-Verlag Berlin Heidelberg 2013
Abstract Anterior cervical discectomy and fusion (ACDF) and anterior lumbar interbody fusion (ALIF) are common surgical procedures for degenerative disc disease of the cervical and lumbar spine. Over the years, many bone graft options have been developed and investigated aimed at complimenting or substituting autograft bone, the traditional fusion substrate. Here, we summarise the historical context, biological basis and current best evidence for these bone graft options in ACDF and ALIF. Keywords Spinal fusion . Anterior cervical discectomy and fusion . Anterior lumbar interbody fusion . Bone graft
Introduction ACDF, ALIF and the use of autograft By the fifth decade of life, approximately 10 % of intervertebral discs are severely degenerated [69]. Anterior cervical discectomy with fusion (ACDF) and anterior lumbar interbody fusion (ALIF) are common surgical procedures used to treat severe degenerative disc disease (DDD) and other indications in the cervical and lumbar spines. These anterior column procedures have many benefits, such as the ability to restore disc height and lordosis, support load A. M. T. Chau : J. H.
