Developing customised, procedure-specific predictive risk met
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Developing customised, procedure-specific predictive risk met
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Methods: The research was conducted among studies published in the Medline database until December 2014. We selected all clinical trials applying ERAS programme in colorectal surgery and reporting outcomes according to clinical and demographic features, BMI and ASA-PS score. Features defining a high-risk subject were advanced age (>80 years), obesity (BMI>30 kg/m2) and elevated ASA-PS scores (III and IV). Outcomes were length of stay (LOS), global postoperative complications, anastomotic leaks, readmission and reoperation rates within 30 postoperative days, and mortality. Results: 6,446 patients from 11 clinical trials were selected and divided into three groups, clustered by advanced age, BMI>30 and ASA III-IV. Highrisk patients responded differently to the application of ERAS protocol in colorectal surgery: age and ASA III-IV had a medium effect on LOS (SMD respectively of 0.464 e p
