Diffusion-weighted and Dynamic Contrast ... - KoreaMed Synapse
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Diffusion-weighted and Dynamic Contrast ... - KoreaMed Synapse
Ji Hyun Koo, Young Cheol Yoon, Jae Hoon Kim. Department of Radiology, Samsung Medical Center, Sungkyunkwan University, College of Medicine, Seoul, ...
www.ksmrm.org
JKSMRM 18(1) : 25-33, 2014
pISSN 1226-9751 / eISSN 2288-3800
http://dx.doi.org/10.13104/jksmrm.2014.18.1.25
Original Article
Diffusion-weighted and Dynamic Contrast-enhanced MRI of Metastatic Bone Tumors: Correlation of the Apparent Diffusion Coefficient, Ktrans and ve values Ji Hyun Koo, Young Cheol Yoon, Jae Hoon Kim Department of Radiology, Samsung Medical Center, Sungkyunkwan University, College of Medicine, Seoul, Korea
Purpose : To investigate whether quantitative parameters derived from Diffusion-weighted magnetic resonance imaging (DW-MRI) correlate with those of Dynamic contrast-enhanced MRI (DCE-MRI). Materials and Methods: Thirteen patients with pathologically or clinically proven bony metastasis who had undergone MRI prior to treatment were included. The voxel size was 1.367×1.367×5 mm. A dominant tumor was selected and the apparent diffusion coefficient (ADC) value and DCE-MRI parameters were obtained by matching voxels. DCE-MRI data were analyzed yielding estimates of Ktrans (volume transfer constant) and ve. (extravascular extracellular volume fraction). Statistical analysis of ADC, Ktrans, and ve value was conducted using Pearson correlation analyses. Results: Fifteen lesions in pelvic bones were evaluated. Of these, 11 showed a statistically significant correlation (P
