PageArticles 1 of 39 in PresS. Am J Physiol Regul Integr Comp Physiol (April 16, 2008). doi:10.1152/ajpregu.00875.2007
Effect of interval versus continuous training on cardiorespiratory and mitochondrial functions: relationship to aerobic performance improvements in sedentary
Frédéric N. Daussin1, Joffrey Zoll1, Stéphane P. Dufour1, Elodie Ponsot1, Evelyne LonsdorferWolf1, Stéphane Doutreleau1, Bertrand Mettauer1,2, François Piquard1, Bernard Geny1, Ruddy Richard1
1
CHRU of Strasbourg, Physiology and Functional Explorations Department, Civil Hospital,
F67091 Strasbourg, France and University Louis Pasteur, Faculty of Medicine, Physiology Department, UPRES E.A. 3072, Strasbourg, France. 2
Cardiology Department, Civil Hospital, F68024 Colmar, France
Address for reprint requests and other correspondence: Frédéric N. Daussin, Service de Physiologie et d’Explorations Fonctionnelles, Hôpital Civil, 1, Place de l’Hôpital, BP 426, F-67091 Strasbourg Cedex, France. Phone : 0033 (0)3 88 11 61 22 Fax : 0033 (0)3 88 11 64 67 E-mail :
[email protected]
Running title: mitochondria adaptations and performance improvement
Copyright © 2008 by the American Physiological Society.
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1 ABSTRACT
The goal of the study was to determine the effects of continuous (CT) vs. intermittent (IT) training yielding identical mechanical work and training duration on skeletal muscle and cardiorespiratory adaptations in sedentary subjects. Eleven subjects (6 men and 5 women, 45±3 years) were randomly assigned to either of the two 8 weeks training programs in a cross-over design, separated by 12 weeks of detraining. Maximal oxygen uptake (VO2max) increased after both trainings (9% with CT vs. 15% with IT), whereas only IT was associated with faster VO2 kinetics (H: 68.0±1.6 vs. 54.9±0.7 sec, p
