Effect of peppermint on pediatrics' pain under endoscopic examination ...

J HerbMed Pharmacol. 2013; 2(2): 41-44.

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Effect of peppermint on pediatrics’ pain under endoscopic examination of the large bowel Mohammad-Ali Kiani1, Ahmad Khodadad2, Shabnam Mohammadi3,*, Majid Ghayour Mobarhan4, Masumeh Saeidi5, Seyed Ali Jafari1, Ebrahim Kiani6, Hamid Ahanchian7 Department of Pediatrics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Department of Pediatrics, School of Medicine, Tehran University of Medical Science, Tehran, Iran 3 Department of Basic Sciences, Faculty of Medicine, Gonabad University of Medical Science, Gonabad, Iran; and Neurogenic Inflammation Research Centre, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 4 Biochemistry of Nutritional Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran 5 Students Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 6 Department of Pediatric, Islamic Azad University, Mashhad, Iran 7 Department of Pediatric, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 1 2

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Introduction: Colonoscopy is a painful and invasive technique for patients especially for pediatrics. Peppermint has analgesic effect. Therefore, we wish to look at the effect of peppermint essence on the patients’ satisfaction and pain after colonoscopy. Methods: This clinical trial study was performed on 100 patient’s candidate for colonoscopy. Patients were randomly divided into two groups. Control group received no drug. Case group was administrated supermint essence thirty minutes before colonoscopy. A valid questionnaire was filled during the colonoscopy for patient’s satisfaction and pain evaluation. Results: The mean value of abdominal pain was 0.527±2.500 in control group and 1.625±0.491 in case group after treatment (p