and Eisai Co, and a research grant from Chugai Pharmaceutical Co. ... 10 Anders HJ, Vielhauer V. Renal co-morbidity in patients with rheumatic diseases.
Letters
Figure 1 Comparisons of (A) serum alanine aminotransferase (ALT) and (B) hepatitis C virus (HCV) viral load before and after biological therapy by Wilcoxon signed-rank test. Biological treatments were categorised by (C) individual biologics and (D) mechanism of action. Data are mean±1 SEM. HCV viral loads were expressed as log10 of the detected values. *p=0.003 by generalised estimating equation.
Acknowledgements The authors are grateful to the Biostatistics Task Force of Taichung Veterans General Hospital, Taiwan, for assistance with statistical analysis. Contributors All authors made substantial intellectual contributions to the conception of the work, analysis and interpretation of the data, and drafting and revising the manuscript.
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Funding None. Competing interests None.
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Patient consent Obtained.
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Ethics approval The Ethics Committee of Taichung Veterans General Hospital. Provenance and peer review Not commissioned; externally peer reviewed.
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To cite Chen Y-M, Chen H-H, Chen Y-H, et al. Ann Rheum Dis 2015;74:626–627.
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Published Online First 1 December 2014 Ann Rheum Dis 2015;74:626–627. doi:10.1136/annrheumdis-2014-206711
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Ann Rheum Dis March 2015 Vol 74 No 3
Effectiveness and safety of tocilizumab therapy for patients with rheumatoid arthritis and renal insufficiency: a real-life registry study in Japan (the ACTRA-RI study) Renal involvement is frequently present in patients with rheumatoid arthritis (RA). Approximately 15–25% of patients with RA have renal insufficiency, defined as a glomerular filtration rate (GFR)