Epidemiology and Antibiotic Resistance Patterns of Bacterial ...
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Epidemiology and Antibiotic Resistance Patterns of Bacterial ...
Conclusion: FQ prophylaxis post-HCT reduces incidence of bacteremia without increasing ... received 86 HCT. Of the group, 41 patients (50%) had a single.
With regard to susceptibility to FQ, 2/19 (10.5%) microbiologically identified organisms in overall FQ cohort were susceptible versus 12/24 (50%) organisms in overall non-FQ cohort (p¼.05). The microbiologically identified organisms were gram negative in 16% of FQ cohort versus 33% of non-FQ cohort (p>.05). Conclusion: FQ prophylaxis post-HCT reduces incidence of bacteremia without increasing CDAD. FQ prophylaxis may lead to higher rates of gram positive and FQ-resistant organisms.
751 Epidemiology and Antibiotic Resistance Patterns of Bacterial Bloodstream Infection Post Allogeneic Hematopoietic Progenitor Cell Transplant e Single Pediatric Center Experience Meghan Hayes 1, William T. Tse 2, Jennifer Schneiderman 3, Reggie E. Duerst 3, Morris Kletzel 4, Sonali Chaudhury 3. 1 Pharmacy, Ann & H Lurie Children’s Hospital of Chicago, Chicago, IL; 2 Hem-Onc-Transplant Division, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, IL; 3 Division of Hematology, Oncology and Stem Cell Transplantation, Ann & Robert H. Lurie Children’s Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL; 4 Northwestern University Feinberg School of Medicine, Chicago, IL Bacterial bloodstream infection (BSI) remains a frequent complication post allogeneic hematopoietic progenitor cell transplant (HCT). The incidence and characteristics of infection are affected by a number of factors. We sought to retrospectively analyze the occurrence of BSI, patterns of antibiotic resistance, and impact on outcomes in pediatric allogeneic HCT recipients. Electronic medical records of 167 consecutive pediatric allogeneic HCT recipients (
