Estimated glomerular filtration rate in patients with type 2 diabetes ...

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Keywords: type 2 diabetes mellitus, kidney function tests, kidney failure, chronic, public health. INTRODUCTION. Assessment of renal function in individuals with ...
ORIGINAL ARTICLE

Estimated glomerular filtration rate in patients with type 2 diabetes mellitus

Estimated glomerular filtration rate in patients with type 2 diabetes mellitus Paula Caitano Fontela1, Eliane Roseli Winkelmann2*, Joice Nedel Ott3, Douglas Prestes Uggeri4 Physiotherapy undergraduate student, Regional University of the Northwest of Rio Grande dos Sul State (Unijuí), PIBIC/CNPq grant recipient, Ijuí, RS, Brazil

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PhD - lecturer at the Regional University of the Northwest of Rio Grande do Sul State (Unijuí), Ijuí, RS, Brazil

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Pharmaceutical biochemist - responsible for the Clinical Analysis Laboratory at UNIJUÍ (UNILAB), Ijuí, RS, Brazil

Physician specialized in nephrology - physician at the Ijuí Charity Hospital (HCI), Ijuí, RS, Brazil

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Summary

Study conducted at the Regional University of the Northwest of the State of Rio Grande do Sul, Ijuí, RS.  Article received: 4/1/2013 Accepted for publication: 3/31/2014 *Correspondence: Address: RS 155, Km 06, Vila Santana, Mail Box: 383 Postal Code: 98700-000 Ijuí – RS [email protected] http://dx.doi.org/10.1590/1806-9282.60.06.010

Conflict of interest: none

Objective: to estimate the glomerular filtration using the Cockcroft-Gault (CG), Modification of Diet in Renal Disease (MDRD), and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations, and serum creatinine in the screening of reduced renal function in patients with type two diabetes (T2DM) enrolled in the Family Health Strategy (ESF, Brazilian federal healthcare program). Methods: a cross-sectional descriptive and analytical study was conducted. The protocol consisted of sociodemographics, physical examination and biochemical tests. Renal function was analyzed through serum creatinine and glomerular filtration rate (GFR) estimated according to the CG, MDRD and CKD-EPI equations, available on the websites of the Brazilian Nephrology Society (SBN) and the (NKF). Results: 146 patients aged 60.9±8.9 years were evaluated; 64.4% were women. The prevalence of serum creatinine >1.2 mg/dL was 18.5% and GFR