Faculty of Allied Health ... Kotelawala Defence University, ... traditional and folk medicine in the treatment of abscesses, wounds and ... Peradeniya, Sri Lanka.
Journal of Pharmacognosy and Phytochemistry 2018; 7(3): 639-642
E-ISSN: 2278-4136 P-ISSN: 2349-8234 JPP 2018; 7(3): 639-642 Received: 08-05-2018 Accepted: 13-06-2018 R Wijerathna Department of Pharmacy, Faculty of Allied Health Sciences, General Sir John Kotelawala Defence University, Werahera, Sri Lanka NAV Asanthi Department of Pharmacy, Faculty of Allied Health Sciences, General Sir John Kotelawala Defence University, Werahera, Sri Lanka WD Ratnasooriya Department of Basic Sciences, Faculty of Allied Health Sciences, General Sir John Kotelawala Defence University, Werahera, Sri Lanka RN Pathirana Department of Basic Sciences, Faculty of Allied Health Sciences, General Sir John Kotelawala Defence University, Werahera, Sri Lanka NRM Nelumdeniya Department of Pharmacy, Faculty of Allied Health Sciences, General Sir John Kotelawala Defence University, Werahera, Sri Lanka
Correspondence R Wijerathna Department of Pharmacy, Faculty of Allied Health Sciences, General Sir John Kotelawala Defence University, Werahera, Sri Lanka
Evaluation of in vitro antibacterial activity and phytochemical profile of aqueous leaf extract of Asystasia variabilis R Wijerathna, NAV Asanthi, WD Ratnasooriya, RN Pathirana and NRM Nelumdeniya Abstract This study evaluated the in vitro antibacterial effect and the phytochemical profile of aqueous extract of fresh mature leaves of Asystasia variabilis, a Sri Lankan indigenous plant, against four common wound infective bacteria (Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa and Escherichia coli) using Kirby-Bauer disk diffusion test. Gentamicin 10 μg/ disk and distilled water was used as positive and negative controls respectively The study revealed, for the first time, that the extract possessed significant antibacterial activity against all four test organisms in a concentration dependent manner (r values ranging from 0.921-0.992, P
