CLINICAL RESEARCH e-ISSN 1643-3750 © Med Sci Monit, 2017; 23: 4715-4722 DOI: 10.12659/MSM.904087
Evaluation of MIh Scoring System in Diagnosis of Obstructive Sleep Apnea Syndrome
Received: 2017.02.28 Accepted: 2017.04.12 Published: 2017.10.02
Authors’ ACEG Contribution: Qinxing Xu Study Design A ABCD Junwei Du Data Collection B BDEF Xiaobo Ling Statistical Analysis C Data Interpretation CEF D Yangfei Lu Manuscript Preparation E Literature Search F Funds Collection G
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Department of Respiratory Medicine, Hangzhou Fuyang First People’s Hospital, Hangzhou, Zhejiang, P.R. China
Qinxing Xu, e-mail:
[email protected] This study was supported by the Science and Technology Bureau of Fuyang District, Hangzhou (2013SF023)
The objective of the present study was to investigate whether the analysis of magnesium (Mg), high-sensitivity C-reactive protein (hsCRP), and ischemia-modified albumin (IMA) concentrations can be used as a non-invasive and convenient method for diagnosing obstructive sleep apnea syndrome (OSAS). After polysomnography, venous blood was collected from 33 patients with OSAS and 30 control individuals. Serum levels of Mg, hsCRP, and IMA were investigated. The relationship between these factors and apnea–hypopnea index (AHI) was analyzed using the Pearson correlation coefficient. The role of the factors was determined using a receiver operating characteristic (ROC) curve and multivariate logistic regression analysis. The levels of hsCRP and IMA were significantly higher in patients with OSAS than in control subjects, while the levels of Mg were lower (P
