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Ibnosina J Med BS
ARTICLE
Evaluation of the Antidiarrheal Activity of Methanol Leaf Extract of Bombax Buonopozense in Rats G. C. Akuodor*1 , I. Muazzam2 , M. Usman-Idris1, U. A. Megwas3, J. L. Akpan4, K. C. Chilaka5, D. O. Okoroafor5, U. A. Osunkwo1
Department of Pharmacology and Toxicology, National Institute for Pharmaceutical Research and Development (NIPRD). 2 Department of Medicinal Plant and Traditional Medicine, National Institute for Pharmaceutical Research and Development (NIPRD), Idu, P.M.B. 21Garki, Abuja, Nigeria. 3 Department of Pharmacology and Therapeutics, Abia State University, Uturu, Nigeria. 4 Department of Pharmacology and Therapeutics, Faculty of Clinical Medicine, Ebonyi State University, Abakiliki, Nigeria. 5 Department of Pharmacology and Therapeutics, Nnamdi Azikiwe University, Awka, Nigeria. 1
*Corresponding author: Akuodor GC Email:
[email protected] Published: 01 January 2011 Ibnosina J Med BS 2011, 3(1):15-20 Received: 25 January 2010 Accepted: 03 December 2010 This article is available from: http://www.ijmbs.org This is an Open Access article distributed under the terms of the Creative Commons Attribution 3.0 License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Objectives: The methanolic extract of the leaves of Bombax buonopozense was screened for antidiarrheal effects. Materials and methods: The extract was evaluated for castor oil- induced diarrhoea and enteropooling as well as intestinal transit in rats. Results: Bombax buonopozense significantly (p
