Evaluation of visual evoked potentials in chronic renal ...

4 downloads 0 Views 188KB Size Report
The renal replacement therapies were standardized ac- cording to Kt/V levels after dialysis according to guidelines to achieve efficient functional renal ...
JNEPHROL 2010 ; 23 ( 06 ) : 705 - 710

ORIGINAL ARTICLE

www.sin-italy.org/jnonline – www.jnephrol.com

Evaluation of visual evoked potentials in chronic renal failure patients with different treatment modalities Pınar Seymen1, Umut Selamet2, Erman Aytac3, Sinan Trabulus4, Hakkı Oktay Seymen5

Abstract Background: Uremia causes central nervous system (CNS) dysfunction. Modern diagnostic methods are useful for the recognition of CNS complications in uremic patients. Data concerning visual evoked potentials (VEPs) of chronic renal failure (CRF) patients is limited. Objective: In this study, we aimed to assess and compare VEPs abnormalities in CRF patients managed by only medical therapy (pre-dialysis) or medical therapy plus renal replacement therapy (continuous ambulatory peritoneal dialysis (CAPD) or hemodialysis (HD)). Materials and methods: Fifty-nine patients diagnosed with CRF of various etiologies were divided into 3 groups according to the treatment modalities used to manage CRF; pre-dialysis group, HD group and CAPD group. For the comparison of VEPs parameters, an age matched control group was formed with 10 healthy subjects. Results: Bilateral N2 latency (p3 months with 706

3-4 exchanges per day, 2000 ml each, over a 24 hour period, adopting a double bag system. Physical examinations were normal in our patients. All subjects gave their consent for inclusion in the study. The investigation conformed to the principles outlined in the Declaration of Helsinki. The patients were divided into 3 groups according to the treatment modalities used to manage CRF; pre-dialysis group, HD group and CAPD group. The renal replacement therapies were standardized according to Kt/V levels after dialysis according to guidelines to achieve efficient functional renal replacement. Kt/V level should not be