Examining and interpreting responsiveness of the ... - CiteSeerX
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Journal of Medical Economics, 2009; 12(4): 309â316. ORIGINAL ARTICLE. Examining and interpreting responsiveness of the. Diabetes Medication Satisfaction ...
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Journal of Medical Economics, 2009; 12(4): 309–316
ORIGINAL ARTICLE
Examining and interpreting responsiveness of the Diabetes Medication Satisfaction measure Meryl Brod1, Torsten Christensen2, Jens Harald Kongsø2, Donald M. Bushnell3 The Brod Group, Mill Valley, CA, USA; 2Novo Nordisk A/S, Bagsværd, Denmark; 3Health Research Associates, Mountlake Terrace, WA, USA Abstract Objective: Treatment satisfaction (TS) is an important patient reported outcome (PRO) in diabetes as it is correlated with outcomes necessary for optimal treatment (e.g., compliance, self-management behaviour). The objective of this study was to examine the responsiveness of the DiabMedSat, a diseasespecific PRO measure, assessing Overall, Burden, Efficacy and Symptom TS. Methods: The DiabMedSat was included in an open label, observational study of the safety and efficacy of biphasic insulin aspart 30 (NovoMix 30*) in routine practice with type 2 diabetes. Responsiveness analyses, examining both internal and external responsiveness, were conducted and minimally important differences (MID) assessed. Results: In 18,817 patients, all TS scores significantly improved after 26 weeks of treatment (p
