Fall 2008 Sample Midterm

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Section 1 Multiple Choice and Matching (40 marks). 1. For the set below ... raised , the virology behind the story and your own conclusions. 2. Describe in detail ...
Sample Mid term Questions: Note, we might not yet have taken some of these, but it should give you a good idea of the kinds of questions to expect. Section 1 Multiple Choice and Matching (40 marks). 1. For the set below match the numbered items with the corresponding letter, a to e to the right. Enter the letter (a to e) next to the question number in the appropriate box on the computer card. please note any item a to e might be correct more than once. SET I 1. Egyptian bas relief (1500 BC) 2. Cervical cancer 3. Louis Pasteur and Joseph Meister 4. Dimitri Ivanovski (1892) 5. Lady Mary Wortley Montague

a. smallpox b. poliovirus c. rabies virus d. Human papilloma virus e. tobacco mosaic virus

In the multiple choice questions below, only one answer is correct, enter the letter corresponding to the correct choice on the computer card on the same row number as the question number. 6. The first virus which was shown to be filterable is the one that causes a) tobacco mosaic disease. b) diphtheria. c) foot and mouth disease d) rabies. e) anthrax. 7. An infectious circular RNA which does not use a protein coat would be considered a a) viroid. b) virusoid. c) prion. d) Hepatitis delta agent. e) satellite virus. 8. The largest dsDNA virus has a genome size of around a) 50 kb. b) less than 50 kb. c) about 100 kb. d) about 300 kb. e) greater than 1,000 kb. Short answer Questions (10 marks each) 1. Describe the nature of one of the main news stories involving a virus, any controversies it raised, the virology behind the story and your own conclusions. 2. Describe in detail the genome of HIV, labelling all parts. Long Answer Question (30 marks) 1. Describe in detail the replication cycle of X, Y or Z virus.