fusion targeted biopsy and concurrent systematic - BMC Urology
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fusion targeted biopsy and concurrent systematic - BMC Urology
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Hakozaki et al. BMC Urology (2017) 17:117 DOI 10.1186/s12894-017-0310-7
RESEARCH ARTICLE
Open Access
A prospective study of magnetic resonance imaging and ultrasonography (MRI/US)fusion targeted biopsy and concurrent systematic transperineal biopsy with the average of 18-cores to detect clinically significant prostate cancer Yuji Hakozaki1* , Hisashi Matsushima1, Jimpei Kumagai4, Taro Murata1, Tomoko Masuda1, Yoko Hirai1, Mai Oda2, Nobuo Kawauchi2, Munehiro Yokoyama3 and Yukio Homma4
Abstract Background: This study compared the detection rates for clinically significant prostate cancer (CSPC) between magnetic resonance imaging and ultrasonography (MRI/US)-fusion-targeted biopsy (TB), systematic biopsy (SB) and combination of TB and SB. Methods: This prospective study evaluated simultaneous TB and SB for consecutive patients with suspicious lesions that were detected using pre-biopsy multiparametric MRI. A commercially available real-time virtual sonography system was used to perform the MRI/US-fusion TB with the transperineal technique. The prostate imaging reporting and data system version 2 (PI-RADS v2) was assigned to categorize the suspicious lesions. Results: A total of 177 patients were included in this study. The detection rate for CSPC was higher using SB, compared to TB (57.1% vs 48.0%, p = 0.0886). The detection rate for CSPC was higher using the combination of TB and SB, compared to only SB (63.3% vs 57.1%, p = 0.2324). Multivariate analysis revealed that PIRADS v2 category 4 and an age of
