Genetic Variation in the TAS2R38 Bitter Taste Receptor and Gastric Cancer Risk in Koreans Jeong-Hwa Choi1, Jeonghee Lee1, Il Ju Choi2, Young-Woo Kim2, Keun Won Ryu2 and Jeongseon Kim1* 1
Molecular Epidemiology Branch, Division of Cancer Epidemiology and Prevention, 2Center for Gastric Cancer, National Cancer Center 323 Ilsan-ro, Ilsandong-gu, Goyang-si, Gyonggi-do, 410-769, Korea. *
Corresponding Author: Jeongseon Kim,
[email protected]
Supplemental Table S1. The results of the power analysis for each dietary variable Variables Energy Fibre Vegetables Cruciferous Dark green Non-starchy Fruits Citrus Sweets Fat-food Alcohol Tobacco
Power 0.277 0.113 0.228 0.344 0.184 0.334 0.234 0.305 0.091 0.208 0.409 0.131
Supplemental Table S2. The effect of potential confounders in logistic regression models for association between the TAS2R38 diplotype and gastric cancer risk
Gender Age Smoking status
Drinking status
Regular exercise Helicobacter pylori infection Body mass index
Effect Male Female Year Never Former Current Never Former Current Yes No Negative Positive Kg/m2
Odds Ratio (95% Confidence Interval) Reference (1.000) 0.715 (0.484 - 1.055) 1.044 (1.029 - 1.059) Reference (1.000) 1.140 (0.761 - 1.708) 2.129 (1.405 - 3.227) Reference (1.000) 1.406 (0.902 - 2.192) 1.094 (0.810 - 1.478) Reference (1.000) 2.184 (1.694 - 2.815) Reference (1.000) 6.651 (4.605 - 9.605) 0.961 (0.921 - 1.002)
p-value 0.091
