ACI (Acta Cardiologia Indonesiana) (Vol.4 No.2): 95-102
Correlation between Triglyceride/HDL Ratio with Severity of Coronary Artery Lesion in Non-Diabetic Stable Angina Pectoris Patients Pramon Aditya Sudjana*, Chaerul Achmad, Achmad Fauzi Yahya, Januar W. Martha, M. Rizki Akbar Department of Cardiology and Vascular Medicine, Hasan Sadikin Hospital, Bandung, Indonesia
*Corresponding author: Pramon Aditya Sudjana MD., - email:
[email protected] Address: Cardiac Center 7th floor, Hasan Sadikin Hospital, Jalan Pasteur No. 38, Bandung, West Java 40161, Phone: +6222-2551111, Indonesia Manuscript submitted: August 24, 2018; Revised and accepted: October 4, 2018
ABSTRACT Background: Triglycerides (TG) as a risk factor for coronary artery disease (CAD) is still a matter of controversy but when used as a single ratio with high density lipoprotein (HDL) the predictive value for CAD is better. The TG/HDL ratio is also associated with the presence of small dense LDL (sdLDL) in the body. SdLDL is a more atherogenic LDL subfraction and has been proven to be associated with CAD progression. Aims: This study aims to find the correlation between the TG/HDL ratio and the degree of coronary lesion severity based on the Gensini score in stable non diabetic angina pectoris patients. Methods: This study was a cross sectional study conducted at Dr. Hasan Sadikin Hospital and Hasna Medika Palimanan Hospital. Subjects were non diabetic stable angina pectoris patients ≥18 years old who underwent elective coronary angiography. Blood collection for TG and HDL examination was performed after coronary angiography. Gensini scoring system was used to assess the severity of coronary lesions. The relationship between the TG/HDL ratio and the Gensini score was analyzed using multiple linear regression tests against confounding variables. Results: This study involved 60 patients with stable angina pectoris with a mean age of 60±8 years. The mean TG/HDL ratio is 2.56 ± 1.04. The average Gensini score was 51 ± 36. The TG/HDL ratio was significantly associated with the Gensini score (R = 0.637; p
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