CONCLUSION: A s ignificant im prove m e nt in ph ys ical and m e ntal H RQOL w as obs e rve d in patie nts s uffe ring from H CC unde rgoing TACE.
ORIGINAL ARTICLE
HEALTH RELATED QUALITY OF LIFE IN PATIENTS UNDERGOING TRANSARTERIAL CHEMOEMBOLIZATION FOR UNRESECTABLE HEPATOCELLULAR CARCINOMA Nauman Al-Qamari, Amjad Sattar, Hatem Adel Dow Ins titute ofRadiol ogy, Dow Unive rs ity ofH e al th Scie nce s , K arach i, Pak is tan PJR April - June 2018; 28(2): 104-108
ABSTRACT O BJECTIVE: To de te rm ine th e h e al th re l ate d q ual ity of l ife (H RQO L) in patie nts unde rgoing trans arte rial ch e m oe m bol iz ation (TACE) for h e patoce l l ul ar carcinom a (H CC). M ETH O DS: A be fore and afte r s urve y w as conducte d from Fe bruary 2014 til lDe ce m be r 2015 and al lpatie nts w h o unde rw e ntTACE irre s pe ctive ofage and ge nde r w ith at l e as t one fol l ow up afte r 06 w e e k s ofTACE w e re incl ude d. Patie nts w h o l os t to fol l ow up w e re e xcl ude d. Sh ort form 12 (SF-12) q ue s tionnaire s w e re us e d to as s e s s H RQO L be fore and afte r TACE. Th e s e inform ation al ong w ith de m ograph ic of th e patie nts l ik e age , ge nde r, duration offol l ow -up, bil irubin l e ve l , tum or s iz e , and ch il d s core w as cal cul ate d. RESULTS: O ut of total53 patie nts , m al e pre ponde rance w as found to be h igh e r 42 (79 .2% ) th an th at of fe m al e s 11 (20.8% ). M ajority of th e patie nts pre s e nte d w ith h e patitis C (n=47, 88.7% ) w h e re as h e patitis B infe ction w as found in 6 (11.3% ) patie nts . Ch il d-Pugh Score “B” w as found in m ajority (n=34, 64.2% ) of th e patie nts , fol l ow e d by Ch il d-Pugh Score “A” in 17 (32.1% ) w h e re as onl y 2 (3.8% ) patie nts w e re pre s e nte d w ith Ch il d-Pugh Score “C”. A s ignificant diffe re nce w as obs e rve d in th e ph ys icaland m e ntal q ual ity of l ife (QO L) be fore and afte r TACE, i.e . 45.3 (42.2-47) vs . 46.2 (44.2-47.2), p-val ue