HEPATOPROTECTIVE ACTIVITY OF LIGNAN ...

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Nov 23, 2013 - Key words: Lignan, flaxseed, paracetamol, induced hepato- ... Twenty four (24) adult male rabbits belonging to the New Zealand White species ...
WORLD JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Essam et al.

World Journal of Pharmacy and Pharmaceutical Sciences

Volume 3, Issue 1, 56-72.

Research Article

ISSN 2278 – 4357

HEPATOPROTECTIVE ACTIVITY OF LIGNAN COMPOUND FROM FLAXSEED (Linumusitatissimum L.) AGAINST ACETAMINOPHENINDUCED HEPATOTOXICITY IN RABBITS *Essam F. Al-Jumaily and Ahmed H. AL-Azawi

Biotechnology Dept. ;Genetic Engineering and Biotechnology Institute for post graduate studies. Baghdad University, Baghdad, Iraq. Article Received on 25 October 2013, Revised on 23 November 2013, Accepted on 16 December 2013

ABSTRACT The hepato-nephroprotective effect of the flaxseed lignan was evaluated in paracetamol-induced hepato-nephrotoxicity in rabbits. Biochemical studies show that there is an significantly increased (p