*Department of Paediatrics and Child Health, Desmond Tutu TB Centre, Stellenbosch University and Tygerberg. Children's Hospital, Cape Town, â Department ...
INT J TUBERC LUNG DIS 13(7):868–874 © 2009 The Union
High prevalence of Mycobacterium tuberculosis infection and disease in children and adolescents with type 1 diabetes mellitus E. A. Webb,*† A. C. Hesseling,* H. S. Schaaf,* R. P. Gie,* C. J. Lombard,‡ A. Spitaels,† S. Delport,† B. J. Marais,* K. Donald,† P. Hindmarsh,§ N. Beyers* * Department of Paediatrics and Child Health, Desmond Tutu TB Centre, Stellenbosch University and Tygerberg Children’s Hospital, Cape Town, † Department of Paediatric and Adolescent Endocrinology, Groote Schuur and Red Cross Children’s Hospitals, University of Cape Town, Cape Town, ‡ Biostatistics Unit, Medical Research Council, Tygerberg, South Africa; § Department of Paediatric and Adolescent Endocrinology, Great Ormond Street Children’s Hospital, London, United Kingdom SUMMARY
Western Cape Province, South Africa. To describe the prevalence of tuberculosis (TB) infection and disease in children with type 1 diabetes and to investigate the association between glycaemic control and prevalence of TB infection and disease. D E S I G N : Cross-sectional hospital-based study conducted at two public referral hospitals. All children and adolescents (aged 20 mm). All patients with prevalent and ever TB disease tested negative for HIV. Clinical characteristics of participants with tuberculosis disease Table 2 compares the characteristics of patients with no previous TB, prevalent and ever TB disease. Four of the 16 children with previous TB were diagnosed prior to developing diabetes; these four were all aged
