Higher order multiple pregnancy outcomes in the Maltese islands 2000-2004 Charles Savona-Ventura, Miriam Gatt, Katya Vella, Stephen Grima Abstract Higher order multiple births have increased significantly in the last decades throughout the developed world. In spite of advances in obstetric care seen throughout the second half of the twentieth century, the perinatal outcomes associated with a multiple pregnancy remain associated with increased morbidity and mortality for the mother and the infants. This study attempts to assess the characteristics and outcomes of these maternities in the Maltese population. The National maternity data for 2000-2004 was analysed (19,935 maternities; 20,215 births) and various outcome parameters were statistically compared between higher order births to singleton births using the chi square test. While the twin maternity rate during the period stood at 1.26%, the triplet maternity rate stood at 0.06% and quadruplet maternities 0.01%. Artificial reproductive technology was used in 27.8% of triplets and 50.0% in quadruplets; in contrast to 0.7% in singleton maternities (p
