in the Killing of Ramos Burkitt's Lymphoma B Cell Line ... single treatments, the percentage of cell death ranged from 23% (Rituximab) to 36% (hydroxyurea).
Jan 5, 2017 - 2Department of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
May 20, 2017 - Cutaneous vasculitis is a reported side effect ... Purcell PM. Cutaneous vasculitis induced by ... induced cutaneous leuko cytoclastic vasculitis.
Supplementary Material. Valproic acid induces antimicrobial compound production in. Doratomyces microsporus. Christoph Zutz. 1,2. , Markus Bacher. 6.
VPA is a short-chain fatty acid possessing anticon- vulsant activity, although ...
patients who did not respond to primary therapies, usu- ... Academy of Neurology.
Small cell lung cancer (SCLC) accounts for
Apr 12, 2012 - Temozolomide (TMZ) has become a key therapeutic agent in patients with malignant gliomas; however, its survival benefit remains.
Valproic acid ameliorates coxsackievirus-B3- induced viral myocarditis by modulating. Th17/Treg imbalance. Haibin Jin* and Xiaoming Guo. Abstract.
Hydroxyurea synergizes with valproic acid in wild-type p53 acute myeloid leukaemia. Supplementary Materials. Supplementary Figure S1: (A) OCI-AML3 cells ...
www.impactjournals.com/oncotarget/
Oncotarget, Supplementary Materials 2016
Hydroxyurea synergizes with valproic acid in wild-type p53 acute myeloid leukaemia Supplementary Materials
Supplementary Figure S1: (A) OCI-AML3 cells were treated for 48 hrs with HU (100 µM), VPA (1 mM) or in combination, before cytospun, fixed and immunostained for Nsb-1. Representative image of three independent experiments is shown (N = 2).
the 5 day combiation treatment regime administered in leukeamia mouse models. Arrows indiate dosing days. Dotted line represents 10% weight loss and would be considered toxic.
Supplementary Figure S3: (A) Survival data presented in Kaplan-Meyer curve illustrating the efficacy of HU and VPA and increased
survival of combination therapy for the primary PDX model of AML (log-rank P = 0.0019 vs controls, P = 0.2475 vs HU, P = 0.0057 vs VPA). Arrows indicate days on which animals were dosed with both compounds.
